CCDC150P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1detection of chemical stimulus involved in sensory perception of smell (GO:0050911)8.84345690
2tooth mineralization (GO:0034505)7.87794244
3protein K11-linked deubiquitination (GO:0035871)7.26669209
4seminiferous tubule development (GO:0072520)6.83389120
5positive regulation of RNA splicing (GO:0033120)6.24045571
6positive regulation of protein sumoylation (GO:0033235)6.13713640
7detection of chemical stimulus involved in sensory perception (GO:0050907)5.79356500
8negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)5.36864430
9negative regulation of T-helper cell differentiation (GO:0045623)5.36864430
10cAMP biosynthetic process (GO:0006171)5.29237411
11pre-miRNA processing (GO:0031054)5.03659538
12attachment of spindle microtubules to kinetochore (GO:0008608)4.77310527
13cilium or flagellum-dependent cell motility (GO:0001539)4.73519096
14activation of protein kinase A activity (GO:0034199)4.73027938
15enteric nervous system development (GO:0048484)4.63470122
16regulation of T-helper 2 cell differentiation (GO:0045628)4.53020946
17regulation of protein sumoylation (GO:0033233)4.50926549
18righting reflex (GO:0060013)4.48359151
19negative regulation of alpha-beta T cell differentiation (GO:0046639)4.36313995
20dendritic spine morphogenesis (GO:0060997)4.17672469
21regulation of T-helper 1 cell differentiation (GO:0045625)4.06697014
22detection of chemical stimulus (GO:0009593)4.03297881
23negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.89875440
24retina layer formation (GO:0010842)3.87948757
25embryonic digestive tract morphogenesis (GO:0048557)3.77236736
26neural tube formation (GO:0001841)3.60270456
27single fertilization (GO:0007338)3.57575914
28male meiosis (GO:0007140)3.56356984
29multicellular organism reproduction (GO:0032504)3.49594497
30negative regulation of type 2 immune response (GO:0002829)3.46573856
31axonemal dynein complex assembly (GO:0070286)3.46000665
32chemosensory behavior (GO:0007635)3.43476801
33synaptic transmission, dopaminergic (GO:0001963)3.36363040
34regulation of centriole replication (GO:0046599)3.35892997
35anterior/posterior axis specification, embryo (GO:0008595)3.29932361
36hippo signaling (GO:0035329)3.29850450
37DNA replication-dependent nucleosome assembly (GO:0006335)3.25952176
38DNA replication-dependent nucleosome organization (GO:0034723)3.25952176
39drug transmembrane transport (GO:0006855)3.25399126
40regulation of relaxation of muscle (GO:1901077)3.19399417
41positive regulation of mitochondrial fission (GO:0090141)3.15724071
42regulation of meiosis I (GO:0060631)3.07202513
43centriole replication (GO:0007099)3.06591420
44mitotic metaphase plate congression (GO:0007080)3.00484424
45arachidonic acid secretion (GO:0050482)3.00241555
46icosanoid secretion (GO:0032309)3.00241555
47protein localization to kinetochore (GO:0034501)2.98287636
48endothelial cell differentiation (GO:0045446)2.95123110
49negative regulation of cytosolic calcium ion concentration (GO:0051481)2.93180232
50regulation of DNA methylation (GO:0044030)2.92201920
51hindbrain development (GO:0030902)2.89973372
52histone exchange (GO:0043486)2.87864101
53positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.87422003
54mitotic chromosome condensation (GO:0007076)2.84965476
55negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.83043691
56negative regulation of translation, ncRNA-mediated (GO:0040033)2.83043691
57regulation of translation, ncRNA-mediated (GO:0045974)2.83043691
58negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.82978018
59metaphase plate congression (GO:0051310)2.81604491
60regulation of histone H3-K9 methylation (GO:0051570)2.81331283
61neuronal ion channel clustering (GO:0045161)2.80649050
62left/right axis specification (GO:0070986)2.77152582
63cyclic purine nucleotide metabolic process (GO:0052652)2.75664528
64nephron epithelium morphogenesis (GO:0072088)2.75058337
65nephron tubule morphogenesis (GO:0072078)2.75058337
66single strand break repair (GO:0000012)2.74119014
67microtubule anchoring (GO:0034453)2.73523340
68phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.73480593
69exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.72914177
70ncRNA catabolic process (GO:0034661)2.71127979
71somite rostral/caudal axis specification (GO:0032525)2.70542185
72sister chromatid cohesion (GO:0007062)2.70393390
73positive regulation of T-helper 1 type immune response (GO:0002827)2.69845005
74negative regulation of astrocyte differentiation (GO:0048712)2.69745474
75microtubule depolymerization (GO:0007019)2.69508306
76regulation of acrosome reaction (GO:0060046)2.69142807
77fertilization (GO:0009566)2.68616007
78cilium movement (GO:0003341)2.67964535
79regulation of DNA endoreduplication (GO:0032875)2.66594235
80spindle checkpoint (GO:0031577)2.66112117
81retinal cone cell development (GO:0046549)2.65296679
82cAMP metabolic process (GO:0046058)2.63988711
83phosphatidylserine acyl-chain remodeling (GO:0036150)2.63460101
84nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.63458563
85chromatin remodeling at centromere (GO:0031055)2.60425430
86phosphatidylinositol acyl-chain remodeling (GO:0036149)2.60340211
87protein localization to synapse (GO:0035418)2.59964217
88centrosome duplication (GO:0051298)2.59581496
89cyclic nucleotide biosynthetic process (GO:0009190)2.59162669
90regulation of cAMP-mediated signaling (GO:0043949)2.57943907
91binding of sperm to zona pellucida (GO:0007339)2.57240371
92hepatocyte apoptotic process (GO:0097284)2.57025068
93vocalization behavior (GO:0071625)2.52824166
94negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.52540980
95CENP-A containing nucleosome assembly (GO:0034080)2.52302611
96regulation of centrosome cycle (GO:0046605)2.51107943
97regulation of retinoic acid receptor signaling pathway (GO:0048385)2.50779713
98nuclear pore complex assembly (GO:0051292)2.50252436
99dendritic spine organization (GO:0097061)2.50174481
100embryonic axis specification (GO:0000578)2.48499270

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse6.87663680
2IGF1R_20145208_ChIP-Seq_DFB_Human3.75167238
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.58171440
4VDR_22108803_ChIP-Seq_LS180_Human3.47079131
5EZH2_22144423_ChIP-Seq_EOC_Human3.34686989
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse3.09426155
7AR_21572438_ChIP-Seq_LNCaP_Human3.01066211
8GBX2_23144817_ChIP-Seq_PC3_Human2.68680146
9E2F7_22180533_ChIP-Seq_HELA_Human2.67328449
10POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.30773704
11TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.30773704
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.29295978
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.19519458
14SALL1_21062744_ChIP-ChIP_HESCs_Human2.10502505
15ZNF274_21170338_ChIP-Seq_K562_Hela2.08912295
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.07356868
17AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.05858137
18PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human2.02443883
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.98530215
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.93993086
21SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.90553183
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89801537
23FUS_26573619_Chip-Seq_HEK293_Human1.84392047
24TP53_16413492_ChIP-PET_HCT116_Human1.83249161
25SMAD3_21741376_ChIP-Seq_EPCs_Human1.81688174
26CBP_20019798_ChIP-Seq_JUKART_Human1.79094973
27IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.79094973
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.77155923
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.76746236
30P300_19829295_ChIP-Seq_ESCs_Human1.75440346
31SMAD4_21799915_ChIP-Seq_A2780_Human1.71247450
32UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.69744833
33ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.66212790
34STAT3_23295773_ChIP-Seq_U87_Human1.63131856
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.58216844
36ARNT_22903824_ChIP-Seq_MCF-7_Human1.56546875
37ER_23166858_ChIP-Seq_MCF-7_Human1.49634925
38RXR_22108803_ChIP-Seq_LS180_Human1.47918538
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45925213
40TAF15_26573619_Chip-Seq_HEK293_Human1.44685191
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.44135835
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42844846
43BCAT_22108803_ChIP-Seq_LS180_Human1.41712909
44TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39266637
45SMAD3_21741376_ChIP-Seq_HESCs_Human1.38155461
46BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37174042
47TBL1_22424771_ChIP-Seq_293T_Human1.34967510
48EWS_26573619_Chip-Seq_HEK293_Human1.34587386
49KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.33479128
50KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.33479128
51KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.33479128
52TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.33046161
53AR_25329375_ChIP-Seq_VCAP_Human1.32681451
54FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30955284
55E2F4_17652178_ChIP-ChIP_JURKAT_Human1.29708975
56SMAD4_21741376_ChIP-Seq_EPCs_Human1.28382537
57KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25889956
58AHR_22903824_ChIP-Seq_MCF-7_Human1.24565654
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.24074112
60NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23758034
61TCF4_22108803_ChIP-Seq_LS180_Human1.19783772
62PRDM14_20953172_ChIP-Seq_ESCs_Human1.18613594
63ESR1_20079471_ChIP-ChIP_T-47D_Human1.16933573
64SMAD4_21741376_ChIP-Seq_HESCs_Human1.16220990
65ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15449468
66RNF2_27304074_Chip-Seq_NSC_Mouse1.13668779
67TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.11584183
68TCF4_23295773_ChIP-Seq_U87_Human1.10804316
69IRF1_19129219_ChIP-ChIP_H3396_Human1.10577405
70KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.10551163
71KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.10220143
72CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.09379351
73RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09274263
74EP300_21415370_ChIP-Seq_HL-1_Mouse1.08580761
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08378010
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.07922868
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05094694
78PIAS1_25552417_ChIP-Seq_VCAP_Human1.04477924
79TBX3_20139965_ChIP-Seq_ESCs_Mouse1.03632860
80GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.03539249
81CJUN_26792858_Chip-Seq_BT549_Human1.03424395
82HNFA_21074721_ChIP-Seq_CACO-2_Human1.03254030
83CBX2_27304074_Chip-Seq_ESCs_Mouse1.03246127
84TBX3_20139965_ChIP-Seq_MESCs_Mouse1.02966429
85PHF8_20622853_ChIP-Seq_HELA_Human1.01057321
86RUNX2_22187159_ChIP-Seq_PCA_Human1.00882319
87BMI1_23680149_ChIP-Seq_NPCS_Mouse0.99750885
88EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99501099
89CDX2_22108803_ChIP-Seq_LS180_Human0.98762058
90NFYB_21822215_ChIP-Seq_K562_Human0.97917379
91FLI1_27457419_Chip-Seq_LIVER_Mouse0.97830498
92PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.97172946
93EZH2_27304074_Chip-Seq_ESCs_Mouse0.96030133
94HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95643671
95GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.94735551
96CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.93880679
97ISL1_27105846_Chip-Seq_CPCs_Mouse0.93525950
98TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92588413
99STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.91225866
100SMAD3_21741376_ChIP-Seq_ESCs_Human0.90360337

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005084_abnormal_gallbladder_morpholo5.77219476
2MP0008961_abnormal_basal_metabolism5.21509464
3MP0003718_maternal_effect3.61332035
4MP0003136_yellow_coat_color2.80047112
5MP0008057_abnormal_DNA_replication2.68849387
6MP0004264_abnormal_extraembryonic_tissu2.63173122
7MP0003890_abnormal_embryonic-extraembry2.29749024
8MP0010094_abnormal_chromosome_stability2.20895433
9MP0006072_abnormal_retinal_apoptosis2.11474913
10MP0006292_abnormal_olfactory_placode2.07156985
11MP0004130_abnormal_muscle_cell1.99341836
12MP0003693_abnormal_embryo_hatching1.91801456
13MP0002102_abnormal_ear_morphology1.81248486
14MP0008058_abnormal_DNA_repair1.75896319
15MP0005646_abnormal_pituitary_gland1.73402860
16MP0003315_abnormal_perineum_morphology1.71765520
17MP0004133_heterotaxia1.70126470
18MP0003646_muscle_fatigue1.68351337
19MP0005410_abnormal_fertilization1.68318453
20MP0002751_abnormal_autonomic_nervous1.68128431
21MP0003937_abnormal_limbs/digits/tail_de1.67730495
22MP0003252_abnormal_bile_duct1.61388232
23MP0001293_anophthalmia1.60276480
24MP0009697_abnormal_copulation1.60156038
25MP0001929_abnormal_gametogenesis1.56505924
26MP0005394_taste/olfaction_phenotype1.55825906
27MP0005499_abnormal_olfactory_system1.55825906
28MP0008789_abnormal_olfactory_epithelium1.54071894
29MP0000749_muscle_degeneration1.51524775
30MP0003941_abnormal_skin_development1.48269764
31MP0008877_abnormal_DNA_methylation1.47534802
32MP0004272_abnormal_basement_membrane1.47042103
33MP0002837_dystrophic_cardiac_calcinosis1.39924555
34MP0005395_other_phenotype1.38014360
35MP0003077_abnormal_cell_cycle1.36256650
36MP0010030_abnormal_orbit_morphology1.34351920
37MP0008932_abnormal_embryonic_tissue1.32399571
38MP0005187_abnormal_penis_morphology1.31723007
39MP0002160_abnormal_reproductive_system1.29946376
40MP0003121_genomic_imprinting1.28458752
41MP0002233_abnormal_nose_morphology1.26266332
42MP0001986_abnormal_taste_sensitivity1.25330311
43MP0003943_abnormal_hepatobiliary_system1.23739432
44MP0002210_abnormal_sex_determination1.23268618
45MP0003698_abnormal_male_reproductive1.22652933
46MP0008995_early_reproductive_senescence1.22508921
47MP0000383_abnormal_hair_follicle1.21216384
48MP0003111_abnormal_nucleus_morphology1.18705017
49MP0002084_abnormal_developmental_patter1.17019885
50MP0001529_abnormal_vocalization1.16405326
51MP0000579_abnormal_nail_morphology1.14647146
52MP0002127_abnormal_cardiovascular_syste1.12489723
53MP0001299_abnormal_eye_distance/1.09400775
54MP0003119_abnormal_digestive_system1.08015958
55MP0005253_abnormal_eye_physiology1.07276716
56MP0001984_abnormal_olfaction1.06177188
57MP0000049_abnormal_middle_ear1.05795388
58MP0000566_synostosis1.04731673
59MP0004084_abnormal_cardiac_muscle1.03685027
60MP0000427_abnormal_hair_cycle1.02497631
61MP0002697_abnormal_eye_size1.02449709
62MP0003935_abnormal_craniofacial_develop1.01594209
63MP0002161_abnormal_fertility/fecundity1.00806428
64MP0004197_abnormal_fetal_growth/weight/1.00173534
65MP0009703_decreased_birth_body0.97607140
66MP0002928_abnormal_bile_duct0.97188360
67MP0000631_abnormal_neuroendocrine_gland0.95279873
68MP0000653_abnormal_sex_gland0.94169986
69MP0003938_abnormal_ear_development0.93376886
70MP0005379_endocrine/exocrine_gland_phen0.92482671
71MP0003699_abnormal_female_reproductive0.90036607
72MP0001270_distended_abdomen0.89246768
73MP0010678_abnormal_skin_adnexa0.89217254
74MP0005391_vision/eye_phenotype0.88695375
75MP0005248_abnormal_Harderian_gland0.88539359
76MP0004957_abnormal_blastocyst_morpholog0.86796494
77MP0005551_abnormal_eye_electrophysiolog0.85239370
78MP0002269_muscular_atrophy0.82495851
79MP0001145_abnormal_male_reproductive0.82056557
80MP0000470_abnormal_stomach_morphology0.80777897
81MP0005448_abnormal_energy_balance0.80570252
82MP0003755_abnormal_palate_morphology0.80060990
83MP0002085_abnormal_embryonic_tissue0.79244892
84MP0003950_abnormal_plasma_membrane0.78865425
85MP0005408_hypopigmentation0.78066418
86MP0010307_abnormal_tumor_latency0.76977120
87MP0010368_abnormal_lymphatic_system0.76459434
88MP0003283_abnormal_digestive_organ0.76403621
89MP0003861_abnormal_nervous_system0.76012042
90MP0004215_abnormal_myocardial_fiber0.75422375
91MP0001119_abnormal_female_reproductive0.75089603
92MP0001286_abnormal_eye_development0.75028654
93MP0005380_embryogenesis_phenotype0.73728510
94MP0001672_abnormal_embryogenesis/_devel0.73728510
95MP0005220_abnormal_exocrine_pancreas0.73344570
96MP0002098_abnormal_vibrissa_morphology0.72003451
97MP0003936_abnormal_reproductive_system0.71425126
98MP0000762_abnormal_tongue_morphology0.70901237
99MP0005389_reproductive_system_phenotype0.70504457
100MP0003567_abnormal_fetal_cardiomyocyte0.70383638

Predicted human phenotypes

RankGene SetZ-score
1Amelogenesis imperfecta (HP:0000705)5.15015677
2Osteomalacia (HP:0002749)4.76052802
3Overgrowth (HP:0001548)4.63479806
4Volvulus (HP:0002580)4.61651550
5Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.87093113
6Chromosomal breakage induced by crosslinking agents (HP:0003221)3.81552756
7Abnormality of the dental pulp (HP:0006479)3.74806545
8Chromsome breakage (HP:0040012)3.68772562
9Abnormality of calcium-phosphate metabolism (HP:0100530)3.54401463
10Polyuria (HP:0000103)3.53913004
11Abnormality of renal resorption (HP:0011038)3.35565959
12Abnormality of dental color (HP:0011073)3.27798630
13Ectopic kidney (HP:0000086)3.24277139
14Cerebellar dysplasia (HP:0007033)3.02110460
15Abnormal urine output (HP:0012590)2.87083707
16Tubulointerstitial nephritis (HP:0001970)2.77454445
17Chronic bronchitis (HP:0004469)2.75923735
18Abnormality of the ileum (HP:0001549)2.73538413
19Aplasia/Hypoplasia of the uvula (HP:0010293)2.70150738
20Septo-optic dysplasia (HP:0100842)2.64795420
21Abnormality of midbrain morphology (HP:0002418)2.62512477
22Molar tooth sign on MRI (HP:0002419)2.62512477
23Meckel diverticulum (HP:0002245)2.61191913
24Lip pit (HP:0100267)2.60790114
25Abnormal respiratory motile cilium physiology (HP:0012261)2.58242863
26Nephronophthisis (HP:0000090)2.56943694
27Intestinal atresia (HP:0011100)2.53842821
28Rhinitis (HP:0012384)2.41700305
29Optic nerve hypoplasia (HP:0000609)2.41369877
30Abnormality of chromosome stability (HP:0003220)2.41357673
31Abnormality of renal excretion (HP:0011036)2.35689161
32Supernumerary spleens (HP:0009799)2.32094629
33Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.28422077
34Drooling (HP:0002307)2.27870663
35Absent radius (HP:0003974)2.26930384
36Depressed nasal tip (HP:0000437)2.21209062
37Small hand (HP:0200055)2.21110343
38Small intestinal stenosis (HP:0012848)2.16957768
39Duodenal stenosis (HP:0100867)2.16957768
40Aplasia involving forearm bones (HP:0009822)2.13312960
41Absent forearm bone (HP:0003953)2.13312960
42Dynein arm defect of respiratory motile cilia (HP:0012255)2.11382767
43Absent/shortened dynein arms (HP:0200106)2.11382767
44Aplasia/Hypoplasia of the earlobes (HP:0009906)2.09711834
45Abnormal lung lobation (HP:0002101)2.08911257
46Abnormality of the preputium (HP:0100587)2.07782613
47Abnormality of the renal medulla (HP:0100957)2.07424866
48Truncal obesity (HP:0001956)2.06122523
49Nephroblastoma (Wilms tumor) (HP:0002667)2.05788119
50Oligodactyly (hands) (HP:0001180)2.05727632
51Gastrointestinal atresia (HP:0002589)2.02621927
52Abnormality of DNA repair (HP:0003254)2.02461238
53Embryonal renal neoplasm (HP:0011794)2.02351064
54Abnormality of the duodenum (HP:0002246)2.01166943
55Excessive salivation (HP:0003781)1.99134096
56Gonadotropin excess (HP:0000837)1.90302986
57Intestinal fistula (HP:0100819)1.88306817
58Chronic hepatic failure (HP:0100626)1.87614231
59High anterior hairline (HP:0009890)1.84726540
60Facial hemangioma (HP:0000329)1.84234451
61Bifid tongue (HP:0010297)1.81047058
62Sloping forehead (HP:0000340)1.80490131
63Preauricular skin tag (HP:0000384)1.79082084
64Lipoatrophy (HP:0100578)1.78962016
65Absent septum pellucidum (HP:0001331)1.78196225
66Preaxial foot polydactyly (HP:0001841)1.78118491
67Clubbing of toes (HP:0100760)1.78111294
68Anophthalmia (HP:0000528)1.77699538
69Rhabdomyosarcoma (HP:0002859)1.77586986
70Oculomotor apraxia (HP:0000657)1.76749124
71Abnormal ciliary motility (HP:0012262)1.76429204
72Esophageal atresia (HP:0002032)1.76272104
73Cutaneous finger syndactyly (HP:0010554)1.75381539
74Renal hypoplasia (HP:0000089)1.74000789
75Inability to walk (HP:0002540)1.73541178
76Right ventricular cardiomyopathy (HP:0011663)1.72742689
77Thick eyebrow (HP:0000574)1.71859845
78Abnormality of the septum pellucidum (HP:0007375)1.71727240
79Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.71636751
80Preauricular pit (HP:0004467)1.71319290
81Periauricular skin pits (HP:0100277)1.71319290
82Abnormality of the labia minora (HP:0012880)1.69662411
83Chorioretinal coloboma (HP:0000567)1.69240356
84Impulsivity (HP:0100710)1.68649828
85Duplicated collecting system (HP:0000081)1.68201519
86Wide intermamillary distance (HP:0006610)1.65270070
87Absent rod-and cone-mediated responses on ERG (HP:0007688)1.64307283
88Growth hormone deficiency (HP:0000824)1.63110093
89Calf muscle hypertrophy (HP:0008981)1.62015621
90Tubulointerstitial abnormality (HP:0001969)1.61136681
91Dilated cardiomyopathy (HP:0001644)1.60909162
92Male infertility (HP:0003251)1.60125253
93Pancreatic fibrosis (HP:0100732)1.59704021
94Abnormal respiratory motile cilium morphology (HP:0005938)1.59402640
95Abnormal respiratory epithelium morphology (HP:0012253)1.59402640
96Gaze-evoked nystagmus (HP:0000640)1.59365685
97Highly arched eyebrow (HP:0002553)1.59243067
98Aplasia/Hypoplasia of the tongue (HP:0010295)1.59029914
99Cutaneous syndactyly (HP:0012725)1.58159939
100Abnormality of the calf musculature (HP:0001430)1.58085419

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK26.97942274
2PINK13.57662054
3ZAK3.53389537
4STK33.08154334
5PLK43.05717680
6OBSCN2.83757200
7CASK2.38752873
8STK38L2.13636062
9LATS12.13233589
10PBK1.85829836
11FRK1.85029198
12TNIK1.84698293
13ACVR1B1.84091115
14TTK1.83671828
15NEK21.78575266
16MAP3K91.77758229
17MARK31.75211134
18BMPR1B1.66926384
19AKT31.64171599
20PLK11.61960829
21CDC71.56473715
22SRPK11.50083116
23MAP3K41.39697507
24NUAK11.39658580
25BRSK21.30115632
26PLK31.26593212
27BRD41.23431062
28BLK1.20603619
29MAP4K21.18888704
30MKNK21.08946036
31MELK1.07753746
32PNCK1.05998671
33STK391.02624468
34WNK30.99928904
35WEE10.98717943
36TLK10.98234198
37PLK20.95521495
38AURKB0.92560989
39TGFBR10.91748448
40LATS20.91211890
41MAP2K70.87074544
42BRAF0.85572491
43DMPK0.81813886
44CHEK20.74891702
45ATM0.74271908
46CDK30.71008648
47INSRR0.70146448
48TRIM280.69821755
49EIF2AK30.68106703
50NEK60.67988507
51MAP4K10.67702705
52OXSR10.67013974
53CHEK10.65588791
54STK160.64806841
55PRKD30.64710131
56CAMK1G0.63273155
57EPHA40.63210439
58CDK120.62667465
59ATR0.62249610
60STK380.61078947
61NLK0.59944710
62MKNK10.59880501
63PKN10.59745480
64BUB10.59742511
65CDC42BPA0.59667631
66TSSK60.59442069
67GRK10.56880110
68TAF10.56578368
69FGFR10.55939068
70SGK20.55707242
71CDK10.55638186
72MAP3K130.55280819
73PRKACB0.51152739
74AURKA0.50583157
75ROCK10.49078182
76PIK3CA0.47154659
77MET0.46831408
78VRK10.45917858
79PRKCQ0.44982213
80FGFR20.44210927
81BCR0.44061860
82SGK2230.43604493
83SGK4940.43604493
84CSNK1E0.43195393
85RAF10.41930342
86MST1R0.41690428
87STK40.39206134
88KSR10.37792217
89TIE10.37651564
90MOS0.37412177
91GSK3B0.36018433
92CDK20.35484335
93PRKCE0.34313750
94WNK40.33903381
95CDK70.33550756
96PRKAA10.33074974
97ERBB40.33007194
98ROCK20.32767159
99DYRK30.30858171
100PRKG10.30296679

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047404.73387067
2Ovarian steroidogenesis_Homo sapiens_hsa049132.95654883
3Fanconi anemia pathway_Homo sapiens_hsa034602.13938570
4Longevity regulating pathway - multiple species_Homo sapiens_hsa042132.10464802
5Circadian rhythm_Homo sapiens_hsa047102.07138101
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.01137611
7Hedgehog signaling pathway_Homo sapiens_hsa043402.00084766
8Oocyte meiosis_Homo sapiens_hsa041141.98995221
9Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.95130116
10Basal transcription factors_Homo sapiens_hsa030221.92946609
11Linoleic acid metabolism_Homo sapiens_hsa005911.89478769
12Taste transduction_Homo sapiens_hsa047421.88484732
13Gap junction_Homo sapiens_hsa045401.83399171
14RNA degradation_Homo sapiens_hsa030181.82506474
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.73277984
16Sulfur relay system_Homo sapiens_hsa041221.70547764
17Mismatch repair_Homo sapiens_hsa034301.66795943
18Thyroid hormone synthesis_Homo sapiens_hsa049181.58491690
19Vascular smooth muscle contraction_Homo sapiens_hsa042701.56333517
20Melanogenesis_Homo sapiens_hsa049161.53687484
21Dilated cardiomyopathy_Homo sapiens_hsa054141.51202559
22Salivary secretion_Homo sapiens_hsa049701.50666453
23Longevity regulating pathway - mammal_Homo sapiens_hsa042111.50192948
24Circadian entrainment_Homo sapiens_hsa047131.46148960
25Gastric acid secretion_Homo sapiens_hsa049711.45933361
26Bile secretion_Homo sapiens_hsa049761.43601396
27Cell cycle_Homo sapiens_hsa041101.39094018
28Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.38783048
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.38381483
30Fat digestion and absorption_Homo sapiens_hsa049751.25338181
31Insulin secretion_Homo sapiens_hsa049111.24793258
32Hippo signaling pathway_Homo sapiens_hsa043901.22754664
33DNA replication_Homo sapiens_hsa030301.22378843
34Ether lipid metabolism_Homo sapiens_hsa005651.22149743
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.21581396
36Pancreatic secretion_Homo sapiens_hsa049721.21068424
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.19579217
38Sulfur metabolism_Homo sapiens_hsa009201.17689856
39GABAergic synapse_Homo sapiens_hsa047271.17162761
40Non-homologous end-joining_Homo sapiens_hsa034501.16417581
41Basal cell carcinoma_Homo sapiens_hsa052171.15062329
42Morphine addiction_Homo sapiens_hsa050321.13191981
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12033350
44RNA transport_Homo sapiens_hsa030131.11275489
45Calcium signaling pathway_Homo sapiens_hsa040201.10389708
46Homologous recombination_Homo sapiens_hsa034401.08021153
47Oxytocin signaling pathway_Homo sapiens_hsa049211.05985255
48Dorso-ventral axis formation_Homo sapiens_hsa043201.05836979
49Cocaine addiction_Homo sapiens_hsa050301.05116107
50Glutamatergic synapse_Homo sapiens_hsa047241.00637771
51Collecting duct acid secretion_Homo sapiens_hsa049660.95079498
52Wnt signaling pathway_Homo sapiens_hsa043100.93840026
53Purine metabolism_Homo sapiens_hsa002300.93244885
54Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.91114029
55Nitrogen metabolism_Homo sapiens_hsa009100.91026023
56p53 signaling pathway_Homo sapiens_hsa041150.90531323
57TGF-beta signaling pathway_Homo sapiens_hsa043500.86467798
58Synaptic vesicle cycle_Homo sapiens_hsa047210.86355418
59Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.86095257
60Alcoholism_Homo sapiens_hsa050340.82823399
61RNA polymerase_Homo sapiens_hsa030200.81224899
62Amphetamine addiction_Homo sapiens_hsa050310.81130842
63Nucleotide excision repair_Homo sapiens_hsa034200.79291182
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.77520740
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75802381
66Phototransduction_Homo sapiens_hsa047440.74741632
67cGMP-PKG signaling pathway_Homo sapiens_hsa040220.74554735
68mRNA surveillance pathway_Homo sapiens_hsa030150.73508692
69ECM-receptor interaction_Homo sapiens_hsa045120.69425765
70Lysine degradation_Homo sapiens_hsa003100.68660335
71Steroid hormone biosynthesis_Homo sapiens_hsa001400.68175267
72Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.68116739
73Estrogen signaling pathway_Homo sapiens_hsa049150.67282486
74Pyruvate metabolism_Homo sapiens_hsa006200.64924315
75Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.63263797
76Cholinergic synapse_Homo sapiens_hsa047250.63244660
77Adherens junction_Homo sapiens_hsa045200.62957479
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62886150
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62727004
80GnRH signaling pathway_Homo sapiens_hsa049120.62613634
81Nicotine addiction_Homo sapiens_hsa050330.61831435
82Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.60095462
83Retinol metabolism_Homo sapiens_hsa008300.59240585
84Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.59121528
85Base excision repair_Homo sapiens_hsa034100.57336191
86cAMP signaling pathway_Homo sapiens_hsa040240.56995302
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.55739064
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55706574
89Butanoate metabolism_Homo sapiens_hsa006500.55637123
90Serotonergic synapse_Homo sapiens_hsa047260.54962096
91Vibrio cholerae infection_Homo sapiens_hsa051100.51728562
92Arachidonic acid metabolism_Homo sapiens_hsa005900.50847943
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50178318
94Glucagon signaling pathway_Homo sapiens_hsa049220.49101637
95Systemic lupus erythematosus_Homo sapiens_hsa053220.48573753
96Tight junction_Homo sapiens_hsa045300.47850365
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.44696670
98Steroid biosynthesis_Homo sapiens_hsa001000.40457778
99FoxO signaling pathway_Homo sapiens_hsa040680.38890284
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.33898368

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »