CCDC153

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleoside diphosphate phosphorylation (GO:0006165)9.85307450
2ventricular system development (GO:0021591)9.07756600
3left/right axis specification (GO:0070986)8.38418366
4CTP metabolic process (GO:0046036)8.27143125
5CTP biosynthetic process (GO:0006241)8.27143125
6guanosine-containing compound biosynthetic process (GO:1901070)8.23380627
7pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)7.57581363
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.39824054
9pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)7.23800496
10microtubule bundle formation (GO:0001578)6.53225043
11pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)6.14636775
12regulation of glucose import in response to insulin stimulus (GO:2001273)5.89317829
13intraciliary transport (GO:0042073)5.77657199
14regulation of macrophage chemotaxis (GO:0010758)5.57332157
15pyrimidine nucleoside triphosphate metabolic process (GO:0009147)5.57181147
16nucleotide phosphorylation (GO:0046939)5.52227511
17left/right pattern formation (GO:0060972)5.40300545
18cilium organization (GO:0044782)5.33506434
19regulation of mononuclear cell migration (GO:0071675)5.15014545
20motile cilium assembly (GO:0044458)5.04347542
21one-carbon compound transport (GO:0019755)5.02257889
22brain morphogenesis (GO:0048854)5.01138564
23pyrimidine ribonucleoside biosynthetic process (GO:0046132)4.85011714
24nucleoside diphosphate metabolic process (GO:0009132)4.83260962
25multicellular organismal aging (GO:0010259)4.82182553
26cilium assembly (GO:0042384)4.78289064
27pyrimidine ribonucleotide biosynthetic process (GO:0009220)4.63142489
28protein localization to cilium (GO:0061512)4.58792690
29otic vesicle formation (GO:0030916)4.45726478
30cellular component assembly involved in morphogenesis (GO:0010927)4.30738316
31cilium morphogenesis (GO:0060271)4.23820042
32pyrimidine ribonucleotide metabolic process (GO:0009218)4.20418859
33centriole assembly (GO:0098534)4.15825905
34regulation of microtubule-based movement (GO:0060632)4.15480430
35response to xenobiotic stimulus (GO:0009410)4.13448696
36oxygen transport (GO:0015671)4.08257745
37primary alcohol catabolic process (GO:0034310)4.01100467
38positive regulation of cellular response to insulin stimulus (GO:1900078)3.96823845
39microtubule-based movement (GO:0007018)3.94765535
40axon ensheathment in central nervous system (GO:0032291)3.87418611
41central nervous system myelination (GO:0022010)3.87418611
42vitamin transmembrane transport (GO:0035461)3.80982609
43gas transport (GO:0015669)3.79584320
44diterpenoid biosynthetic process (GO:0016102)3.77632780
45pyrimidine-containing compound transmembrane transport (GO:0072531)3.76894753
46cell projection assembly (GO:0030031)3.76244020
47negative regulation of T cell differentiation in thymus (GO:0033085)3.73597405
48pyrimidine ribonucleoside metabolic process (GO:0046131)3.72066244
49regulation of pigment cell differentiation (GO:0050932)3.71784807
50embryonic digestive tract development (GO:0048566)3.64455707
51heart valve formation (GO:0003188)3.61351220
52nonmotile primary cilium assembly (GO:0035058)3.57000306
53respiratory chain complex IV assembly (GO:0008535)3.56895161
54purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.56136747
55pyrimidine nucleotide biosynthetic process (GO:0006221)3.54980087
56cellular ketone body metabolic process (GO:0046950)3.52899435
57sperm motility (GO:0030317)3.52522404
58ethanol metabolic process (GO:0006067)3.48441037
59centriole replication (GO:0007099)3.46928134
60photoreceptor cell maintenance (GO:0045494)3.46574213
61purine nucleoside triphosphate biosynthetic process (GO:0009145)3.45708602
62photoreceptor cell differentiation (GO:0046530)3.42308295
63eye photoreceptor cell differentiation (GO:0001754)3.42308295
64exogenous drug catabolic process (GO:0042738)3.40871057
65glutathione derivative metabolic process (GO:1901685)3.40219663
66glutathione derivative biosynthetic process (GO:1901687)3.40219663
67negative regulation of inclusion body assembly (GO:0090084)3.39559293
68terpenoid biosynthetic process (GO:0016114)3.38556397
69response to histamine (GO:0034776)3.36967489
70ketone body metabolic process (GO:1902224)3.29543997
71pyrimidine nucleoside biosynthetic process (GO:0046134)3.28447008
72regulation of mesenchymal cell apoptotic process (GO:2001053)3.23146789
73establishment of protein localization to mitochondrial membrane (GO:0090151)3.20566040
74response to pheromone (GO:0019236)3.20562956
75cornea development in camera-type eye (GO:0061303)3.17985040
76platelet dense granule organization (GO:0060155)3.14335431
77endocardial cushion morphogenesis (GO:0003203)3.11254806
78retinal cone cell development (GO:0046549)3.10556255
79retinoic acid metabolic process (GO:0042573)3.09521115
80regulation of male gonad development (GO:2000018)3.08321669
81cytochrome complex assembly (GO:0017004)3.07338061
82positive regulation of meiosis (GO:0045836)3.04906979
83retinol metabolic process (GO:0042572)3.02945051
84ribonucleoside triphosphate biosynthetic process (GO:0009201)3.02654126
85water-soluble vitamin biosynthetic process (GO:0042364)2.99492466
86tolerance induction (GO:0002507)2.99324823
87aldehyde catabolic process (GO:0046185)2.96471770
88positive regulation of extracellular matrix organization (GO:1903055)2.96470108
89negative regulation of humoral immune response (GO:0002921)2.95732936
90hydrogen peroxide biosynthetic process (GO:0050665)2.94600063
91limb bud formation (GO:0060174)2.94055976
92lateral ventricle development (GO:0021670)2.92313931
93cerebral cortex neuron differentiation (GO:0021895)2.91603698
94nucleoside triphosphate biosynthetic process (GO:0009142)2.89708496
95organic cation transport (GO:0015695)2.87169061
96hair follicle development (GO:0001942)2.85400793
97regulation of inclusion body assembly (GO:0090083)2.83180819
98nephron tubule formation (GO:0072079)2.82758684
99negative regulation of B cell mediated immunity (GO:0002713)2.79513337
100negative regulation of immunoglobulin mediated immune response (GO:0002890)2.79513337
101positive regulation of developmental pigmentation (GO:0048087)2.78988517
102drug catabolic process (GO:0042737)2.78575849
103positive regulation of meiotic cell cycle (GO:0051446)2.77304671
104retinal rod cell development (GO:0046548)2.76762774
105inositol phosphate catabolic process (GO:0071545)2.75123519
106epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.73606564
107L-fucose catabolic process (GO:0042355)2.71111966
108fucose catabolic process (GO:0019317)2.71111966
109L-fucose metabolic process (GO:0042354)2.71111966
110cytoplasmic microtubule organization (GO:0031122)2.70607740
111DNA deamination (GO:0045006)2.69462284
112polyol catabolic process (GO:0046174)2.66412491
113positive regulation of male gonad development (GO:2000020)2.64641320
114regulation of autophagic vacuole assembly (GO:2000785)2.64102086
115pyrimidine-containing compound biosynthetic process (GO:0072528)2.64090941
116regulation of germinal center formation (GO:0002634)2.63739260
117oligodendrocyte differentiation (GO:0048709)2.63495252
118C-terminal protein amino acid modification (GO:0018410)2.62707616
119preassembly of GPI anchor in ER membrane (GO:0016254)2.61466056
120embryonic camera-type eye development (GO:0031076)2.61067938
121regulation of collateral sprouting (GO:0048670)2.60925416
122C-terminal protein lipidation (GO:0006501)2.60724019
123reactive oxygen species biosynthetic process (GO:1903409)2.60690030
124regulation of interleukin-6 biosynthetic process (GO:0045408)2.59404013
125multicellular organism reproduction (GO:0032504)2.57799717
126phenol-containing compound catabolic process (GO:0019336)2.56622545
127L-ascorbic acid metabolic process (GO:0019852)2.56391966
128sperm capacitation (GO:0048240)2.55998052
129protein complex biogenesis (GO:0070271)2.55295952
130developmental induction (GO:0031128)2.54398959
131inositol phosphate dephosphorylation (GO:0046855)2.53826784
132phosphorylated carbohydrate dephosphorylation (GO:0046838)2.53826784
133pyrimidine nucleotide metabolic process (GO:0006220)2.52972475
134benzene-containing compound metabolic process (GO:0042537)2.52457803
135positive regulation of respiratory burst (GO:0060267)2.52352968
136cell-cell signaling involved in cell fate commitment (GO:0045168)2.51727627
137signal peptide processing (GO:0006465)2.50975215
138regulation of cilium movement (GO:0003352)2.50358079
139ethanol oxidation (GO:0006069)2.50105898
140phosphatidylcholine biosynthetic process (GO:0006656)2.49919542
141regulation of granulocyte chemotaxis (GO:0071622)2.49616079
142mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.45942866
143primary alcohol metabolic process (GO:0034308)2.45618502
144negative regulation of cytosolic calcium ion concentration (GO:0051481)2.43129438
145negative regulation of astrocyte differentiation (GO:0048712)2.41750571
146microtubule depolymerization (GO:0007019)2.40457760
147behavioral response to nicotine (GO:0035095)2.40038883
148regulation of vacuole organization (GO:0044088)2.39744393
149negative regulation of myoblast differentiation (GO:0045662)2.38868806
150spinal cord motor neuron differentiation (GO:0021522)2.38298135
151negative regulation of oligodendrocyte differentiation (GO:0048715)2.36216335
152mesenchyme morphogenesis (GO:0072132)2.34375387
153determination of left/right symmetry (GO:0007368)2.34221913
154smoothened signaling pathway (GO:0007224)2.32714838
155protein palmitoylation (GO:0018345)2.31117868
156determination of bilateral symmetry (GO:0009855)2.22311212
157pyrimidine nucleoside metabolic process (GO:0006213)2.18679925
158specification of symmetry (GO:0009799)2.18374534
159mitotic cell cycle arrest (GO:0071850)2.18310106
160negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.17469315
161ADP metabolic process (GO:0046031)2.16310851
162cellular response to nicotine (GO:0071316)2.15583575
163phosphatidylcholine acyl-chain remodeling (GO:0036151)2.15455673
164regulation of hippo signaling (GO:0035330)2.14486578
165cilium movement (GO:0003341)15.3729510
166axoneme assembly (GO:0035082)15.2751431
167GTP biosynthetic process (GO:0006183)12.2571677
168axonemal dynein complex assembly (GO:0070286)11.7871327
169UTP biosynthetic process (GO:0006228)10.9462586
170epithelial cilium movement (GO:0003351)10.6223036
171cilium or flagellum-dependent cell motility (GO:0001539)10.2507558
172UTP metabolic process (GO:0046051)10.2149766

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human5.07183718
2RBPJ_22232070_ChIP-Seq_NCS_Mouse4.62597123
3CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.84371785
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.18373263
5VDR_22108803_ChIP-Seq_LS180_Human3.02539559
6ZNF274_21170338_ChIP-Seq_K562_Hela2.90601858
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.58910421
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.32282394
9TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.28188625
10PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.09622166
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.07187273
12IGF1R_20145208_ChIP-Seq_DFB_Human2.03368289
13AR_21572438_ChIP-Seq_LNCaP_Human2.01251766
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.88176727
15FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.86650508
16EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.86359046
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.86129565
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.85189173
19GATA1_22025678_ChIP-Seq_K562_Human1.81716875
20GATA1_26923725_Chip-Seq_HPCs_Mouse1.81665812
21P300_19829295_ChIP-Seq_ESCs_Human1.80955873
22SMAD4_21799915_ChIP-Seq_A2780_Human1.79281148
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.78751210
24SUZ12_27294783_Chip-Seq_NPCs_Mouse1.74016448
25SALL1_21062744_ChIP-ChIP_HESCs_Human1.71378521
26JARID2_20075857_ChIP-Seq_MESCs_Mouse1.71298406
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.68309048
28FOXA1_25329375_ChIP-Seq_VCAP_Human1.68111965
29FOXA1_27270436_Chip-Seq_PROSTATE_Human1.68111965
30PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.65332918
31SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.65332863
32BMI1_23680149_ChIP-Seq_NPCS_Mouse1.65151611
33SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.65015784
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.63505694
35CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62736338
36CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.62633665
37JARID2_20064375_ChIP-Seq_MESCs_Mouse1.60912398
38HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.56921219
39BCAT_22108803_ChIP-Seq_LS180_Human1.56622341
40SUZ12_27294783_Chip-Seq_ESCs_Mouse1.56324074
41EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.55281852
42EZH2_27304074_Chip-Seq_ESCs_Mouse1.53671158
43DROSHA_22980978_ChIP-Seq_HELA_Human1.52874422
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.50324958
45AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.49673096
46TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.49577111
47AR_20517297_ChIP-Seq_VCAP_Human1.49025522
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.47835555
49E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.45276273
50NFE2_27457419_Chip-Seq_LIVER_Mouse1.45094623
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44483788
52STAT3_23295773_ChIP-Seq_U87_Human1.44348885
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43916349
54RNF2_27304074_Chip-Seq_NSC_Mouse1.43838732
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.43828565
56NANOG_19829295_ChIP-Seq_ESCs_Human1.43706681
57SOX2_19829295_ChIP-Seq_ESCs_Human1.43706681
58ZFP57_27257070_Chip-Seq_ESCs_Mouse1.43517095
59RNF2_18974828_ChIP-Seq_MESCs_Mouse1.42572117
60EZH2_18974828_ChIP-Seq_MESCs_Mouse1.42572117
61EED_16625203_ChIP-ChIP_MESCs_Mouse1.41732115
62MTF2_20144788_ChIP-Seq_MESCs_Mouse1.40179324
63FOXA1_21572438_ChIP-Seq_LNCaP_Human1.40085716
64ER_23166858_ChIP-Seq_MCF-7_Human1.38849487
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37327828
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36192722
67SMAD3_21741376_ChIP-Seq_EPCs_Human1.34796536
68FOXM1_26456572_ChIP-Seq_MCF-7_Human1.34138721
69EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.34037422
70CBP_20019798_ChIP-Seq_JUKART_Human1.33785072
71IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33785072
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.33784582
73WT1_19549856_ChIP-ChIP_CCG9911_Human1.32637959
74LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31190183
75GABP_17652178_ChIP-ChIP_JURKAT_Human1.29611357
76SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.29464169
77EZH2_22144423_ChIP-Seq_EOC_Human1.28358185
78TCF4_23295773_ChIP-Seq_U87_Human1.27500458
79FLI1_27457419_Chip-Seq_LIVER_Mouse1.27163964
80NCOR_22424771_ChIP-Seq_293T_Human1.27066460
81TP53_22573176_ChIP-Seq_HFKS_Human1.26910944
82CDX2_22108803_ChIP-Seq_LS180_Human1.26866741
83TP53_18474530_ChIP-ChIP_U2OS_Human1.26692032
84PHF8_20622853_ChIP-Seq_HELA_Human1.26065015
85ETV1_20927104_ChIP-Seq_GIST48_Human1.25997704
86NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.25624927
87SMAD4_21741376_ChIP-Seq_EPCs_Human1.24996532
88PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24729065
89GATA3_21878914_ChIP-Seq_MCF-7_Human1.23042363
90P53_22127205_ChIP-Seq_FIBROBLAST_Human1.22666860
91TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22073587
92EZH2_27294783_Chip-Seq_NPCs_Mouse1.21533803
93GBX2_23144817_ChIP-Seq_PC3_Human1.21358391
94SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20531930
95RBPJ_21746931_ChIP-Seq_IB4_Human1.20493997
96STAT3_18555785_Chip-Seq_ESCs_Mouse1.20456979
97LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20116958
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19838542
99NANOG_18555785_Chip-Seq_ESCs_Mouse1.19755350
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19749684
101FUS_26573619_Chip-Seq_HEK293_Human1.19604796
102SMRT_27268052_Chip-Seq_Bcells_Human1.19440698
103ZFX_18555785_Chip-Seq_ESCs_Mouse1.19248305
104HOXB7_26014856_ChIP-Seq_BT474_Human1.19238891
105OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18541849
106* RUNX2_22187159_ChIP-Seq_PCA_Human1.18536741
107ARNT_22903824_ChIP-Seq_MCF-7_Human1.17907657
108STAT1_20625510_ChIP-Seq_HELA_Human1.17840124
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.17733920
110RNF2_27304074_Chip-Seq_ESCs_Mouse1.17233557
111MYC_19829295_ChIP-Seq_ESCs_Human1.16740546
112TCF4_22108803_ChIP-Seq_LS180_Human1.16440300
113AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.15997909
114EGR1_23403033_ChIP-Seq_LIVER_Mouse1.15703395
115KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.14316545
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12820246
117RING1B_27294783_Chip-Seq_ESCs_Mouse1.12603529
118PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.11760500
119* TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11573477
120KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11464883
121CRX_20693478_ChIP-Seq_RETINA_Mouse1.11186754
122SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.11026518
123E2F1_18555785_Chip-Seq_ESCs_Mouse1.10884648
124CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.10858481
125AHR_22903824_ChIP-Seq_MCF-7_Human1.10648400
126HNFA_21074721_ChIP-Seq_CACO-2_Human1.10596844
127FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.09919579
128SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09076798
129EWS_26573619_Chip-Seq_HEK293_Human1.08044348
130CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.07920032
131TAF15_26573619_Chip-Seq_HEK293_Human1.07910685
132SMAD_19615063_ChIP-ChIP_OVARY_Human1.07853838
133ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.07452280
134SOX2_18555785_Chip-Seq_ESCs_Mouse1.07316859
135TP53_20018659_ChIP-ChIP_R1E_Mouse1.06723714
136POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06129784
137CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.05525822
138SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05414242
139NFYA_21822215_ChIP-Seq_K562_Human1.05401535
140SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05363717
141EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.05306969
142TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05274466
143POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05274466
144P300_18555785_Chip-Seq_ESCs_Mouse1.05226604
145SRF_21415370_ChIP-Seq_HL-1_Mouse1.05078085
146STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04997939
147RXR_22108803_ChIP-Seq_LS180_Human1.04690996
148AR_25329375_ChIP-Seq_VCAP_Human1.04523124
149GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.04236256
150UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03961285
151CJUN_26792858_Chip-Seq_BT549_Human1.03867644
152ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03644508
153OCT4_18555785_Chip-Seq_ESCs_Mouse1.03548684
154P53_22387025_ChIP-Seq_ESCs_Mouse1.03281308
155NFYB_21822215_ChIP-Seq_K562_Human1.02740043
156* PRDM14_20953172_ChIP-Seq_ESCs_Human1.01482602
157FOXH1_21741376_ChIP-Seq_EPCs_Human1.01478811
158CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.01435024
159RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01209574
160PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.01039715
161TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00763812
162MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.00536866
163TBL1_22424771_ChIP-Seq_293T_Human0.99978148
164OCT4_21477851_ChIP-Seq_ESCs_Mouse0.99777644

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color9.14099506
2MP0002653_abnormal_ependyma_morphology4.01725451
3MP0008004_abnormal_stomach_pH3.81512117
4MP0005623_abnormal_meninges_morphology3.46718977
5MP0005646_abnormal_pituitary_gland3.42658597
6MP0004381_abnormal_hair_follicle3.04861857
7MP0004043_abnormal_pH_regulation3.03689398
8MP0003724_increased_susceptibility_to2.64278284
9MP0004133_heterotaxia2.47376632
10MP0000372_irregular_coat_pigmentation2.40558079
11MP0002837_dystrophic_cardiac_calcinosis2.37062079
12MP0002249_abnormal_larynx_morphology2.34699564
13MP0009780_abnormal_chondrocyte_physiolo2.31682207
14MP0001440_abnormal_grooming_behavior2.20430303
15MP0001501_abnormal_sleep_pattern2.18094185
16MP0008877_abnormal_DNA_methylation2.14247398
17MP0003195_calcinosis2.10061632
18MP0004019_abnormal_vitamin_homeostasis1.99688754
19MP0002163_abnormal_gland_morphology1.97262001
20MP0006292_abnormal_olfactory_placode1.94270148
21MP0002909_abnormal_adrenal_gland1.91166230
22MP0002254_reproductive_system_inflammat1.83121893
23MP0002282_abnormal_trachea_morphology1.79506073
24MP0008995_early_reproductive_senescence1.77797815
25MP0005377_hearing/vestibular/ear_phenot1.77762869
26MP0003878_abnormal_ear_physiology1.77762869
27MP0001851_eye_inflammation1.77474388
28MP0009046_muscle_twitch1.76796131
29MP0005084_abnormal_gallbladder_morpholo1.73208950
30MP0000015_abnormal_ear_pigmentation1.71478159
31MP0002160_abnormal_reproductive_system1.69501013
32MP0005083_abnormal_biliary_tract1.68732317
33MP0003937_abnormal_limbs/digits/tail_de1.61960406
34MP0008789_abnormal_olfactory_epithelium1.61877977
35MP0003690_abnormal_glial_cell1.61156990
36MP0001958_emphysema1.58205370
37MP0000049_abnormal_middle_ear1.57752202
38MP0004142_abnormal_muscle_tone1.55937226
39MP0005174_abnormal_tail_pigmentation1.55803790
40MP0003303_peritoneal_inflammation1.55591871
41MP0004858_abnormal_nervous_system1.53391856
42MP0001270_distended_abdomen1.50997503
43MP0002938_white_spotting1.46107670
44MP0005388_respiratory_system_phenotype1.45667541
45MP0002133_abnormal_respiratory_system1.45667541
46MP0003806_abnormal_nucleotide_metabolis1.44640576
47MP0000428_abnormal_craniofacial_morphol1.44407818
48MP0002928_abnormal_bile_duct1.44227209
49MP0003938_abnormal_ear_development1.44000908
50MP0002102_abnormal_ear_morphology1.42802399
51MP0003279_aneurysm1.41928930
52MP0005645_abnormal_hypothalamus_physiol1.36518585
53MP0005636_abnormal_mineral_homeostasis1.35216064
54MP0005408_hypopigmentation1.34882076
55MP0001764_abnormal_homeostasis1.32227851
56MP0000383_abnormal_hair_follicle1.31012302
57MP0003950_abnormal_plasma_membrane1.29229926
58MP0001765_abnormal_ion_homeostasis1.27556554
59MP0004885_abnormal_endolymph1.26615653
60MP0006036_abnormal_mitochondrial_physio1.26277182
61MP0009745_abnormal_behavioral_response1.25460045
62MP0002557_abnormal_social/conspecific_i1.24322582
63MP0002693_abnormal_pancreas_physiology1.22391411
64MP0009250_abnormal_appendicular_skeleto1.21116209
65MP0002405_respiratory_system_inflammati1.19924546
66MP0001944_abnormal_pancreas_morphology1.19520341
67MP0002064_seizures1.18646363
68MP0002736_abnormal_nociception_after1.17901415
69MP0002638_abnormal_pupillary_reflex1.17842504
70MP0000427_abnormal_hair_cycle1.13270282
71MP0005075_abnormal_melanosome_morpholog1.12742474
72MP0000569_abnormal_digit_pigmentation1.12444089
73MP0003122_maternal_imprinting1.11484534
74MP0001929_abnormal_gametogenesis1.10498840
75MP0005551_abnormal_eye_electrophysiolog1.10154895
76MP0010678_abnormal_skin_adnexa1.09659567
77MP0005365_abnormal_bile_salt1.09363836
78MP0005310_abnormal_salivary_gland1.09029786
79MP0000778_abnormal_nervous_system1.07950143
80MP0001919_abnormal_reproductive_system1.07761101
81MP0001970_abnormal_pain_threshold1.07194601
82MP0002132_abnormal_respiratory_system1.06440599
83MP0002139_abnormal_hepatobiliary_system1.05873074
84MP0000470_abnormal_stomach_morphology1.05721035
85MP0001968_abnormal_touch/_nociception1.05078151
86MP0003075_altered_response_to1.02018872
87MP0000613_abnormal_salivary_gland1.00382990
88MP0005389_reproductive_system_phenotype1.00151560
89MP0003698_abnormal_male_reproductive0.99498879
90MP0002277_abnormal_respiratory_mucosa0.99253413
91MP0002735_abnormal_chemical_nociception0.99019990
92MP0003787_abnormal_imprinting0.98980879
93MP0003634_abnormal_glial_cell0.98721693
94MP0002734_abnormal_mechanical_nocicepti0.98643654
95MP0002572_abnormal_emotion/affect_behav0.97825904
96MP0001663_abnormal_digestive_system0.97230545
97MP0004859_abnormal_synaptic_plasticity0.97078613
98MP0001324_abnormal_eye_pigmentation0.96001492
99MP0001177_atelectasis0.95420968
100MP0001485_abnormal_pinna_reflex0.95386718
101MP0002168_other_aberrant_phenotype0.95020524
102MP0005379_endocrine/exocrine_gland_phen0.94762297
103MP0003172_abnormal_lysosome_physiology0.94514845
104MP0009384_cardiac_valve_regurgitation0.94331580
105MP0003635_abnormal_synaptic_transmissio0.94169815
106MP0001986_abnormal_taste_sensitivity0.92259884
107MP0006082_CNS_inflammation0.91919114
108MP0004782_abnormal_surfactant_physiolog0.90284523
109MP0008875_abnormal_xenobiotic_pharmacok0.90159805
110MP0000631_abnormal_neuroendocrine_gland0.88778351
111MP0005332_abnormal_amino_acid0.88735229
112MP0001984_abnormal_olfaction0.87927045
113MP0002272_abnormal_nervous_system0.87560796
114MP0001756_abnormal_urination0.87264989
115MP0001486_abnormal_startle_reflex0.83967235
116MP0003646_muscle_fatigue0.83765777
117MP0005085_abnormal_gallbladder_physiolo0.83356461
118MP0002876_abnormal_thyroid_physiology0.82787938
119MP0000026_abnormal_inner_ear0.82661942
120MP0004742_abnormal_vestibular_system0.82389886
121MP0005167_abnormal_blood-brain_barrier0.82171255
122MP0005395_other_phenotype0.81081244
123MP0002229_neurodegeneration0.79503119
124MP0003828_pulmonary_edema0.79272884
125MP0005195_abnormal_posterior_eye0.78572580
126MP0005220_abnormal_exocrine_pancreas0.77048241
127MP0006276_abnormal_autonomic_nervous0.76571328
128MP0001502_abnormal_circadian_rhythm0.76064636
129MP0005595_abnormal_vascular_smooth0.75683821
130MP0003718_maternal_effect0.75420250
131MP0003011_delayed_dark_adaptation0.74945730
132MP0005381_digestive/alimentary_phenotyp0.74603407
133MP0002116_abnormal_craniofacial_bone0.74218264
134MP0002210_abnormal_sex_determination0.73484899
135MP0000762_abnormal_tongue_morphology0.72959556
136MP0005410_abnormal_fertilization0.72568359
137MP0002233_abnormal_nose_morphology0.72419828
138MP0009643_abnormal_urine_homeostasis0.71241970
139MP0001529_abnormal_vocalization0.71052055
140MP0004145_abnormal_muscle_electrophysio0.70787810
141MP0001188_hyperpigmentation0.70320167
142MP0001873_stomach_inflammation0.70238984
143MP0010329_abnormal_lipoprotein_level0.70014204
144MP0002063_abnormal_learning/memory/cond0.69022526
145MP0000653_abnormal_sex_gland0.68449223
146MP0002733_abnormal_thermal_nociception0.67465003
147MP0005394_taste/olfaction_phenotype0.67031790
148MP0002896_abnormal_bone_mineralization0.65809119
149MP0003186_abnormal_redox_activity0.65569414
150MP0005164_abnormal_response_to0.64979915
151MP0008872_abnormal_physiological_respon0.64720803
152MP0005253_abnormal_eye_physiology0.64690561
153MP0000749_muscle_degeneration0.63739779
154MP0001286_abnormal_eye_development0.63151818
155MP0005391_vision/eye_phenotype0.62570749
156MP0001905_abnormal_dopamine_level0.62174590
157MP0002095_abnormal_skin_pigmentation0.61276434
158MP0006072_abnormal_retinal_apoptosis0.60560130
159MP0002067_abnormal_sensory_capabilities0.59494513
160MP0009115_abnormal_fat_cell0.58217941
161MP0001340_abnormal_eyelid_morphology0.56360623
162MP0001879_abnormal_lymphatic_vessel0.55985299

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.41655990
2Abnormal respiratory epithelium morphology (HP:0012253)9.41655990
3Absent/shortened dynein arms (HP:0200106)6.66162313
4Dynein arm defect of respiratory motile cilia (HP:0012255)6.66162313
5Chronic bronchitis (HP:0004469)6.40587552
6Bronchiectasis (HP:0002110)5.67975143
7True hermaphroditism (HP:0010459)5.29095936
8Pancreatic fibrosis (HP:0100732)5.22525251
9Recurrent sinusitis (HP:0011108)4.28337648
10Nasal polyposis (HP:0100582)4.18384935
11Chronic sinusitis (HP:0011109)4.07538167
12Median cleft lip (HP:0000161)3.60495304
13Abnormality of the nasal mucosa (HP:0000433)3.53298237
14Pancreatic cysts (HP:0001737)3.53192629
15Neoplasm of head and neck (HP:0012288)3.48716339
16Esophageal neoplasm (HP:0100751)3.48716339
17Bronchitis (HP:0012387)3.38493797
18Occipital encephalocele (HP:0002085)3.35983624
19Nephronophthisis (HP:0000090)3.15450369
20Bile duct proliferation (HP:0001408)3.05568993
21Abnormal biliary tract physiology (HP:0012439)3.05568993
22Supernumerary spleens (HP:0009799)2.92072706
23Congenital hepatic fibrosis (HP:0002612)2.89080053
24Cystic liver disease (HP:0006706)2.85469470
25Postaxial foot polydactyly (HP:0001830)2.84906140
26Tubulointerstitial nephritis (HP:0001970)2.84071023
27Abnormality of midbrain morphology (HP:0002418)2.83333926
28Molar tooth sign on MRI (HP:0002419)2.83333926
29Abnormality of dentin (HP:0010299)2.78347397
30Chronic hepatic failure (HP:0100626)2.75790975
31Sex reversal (HP:0012245)2.74605224
32Abnormal sex determination (HP:0012244)2.74605224
33Aplasia/Hypoplasia of the tongue (HP:0010295)2.70729254
34Neonatal short-limb short stature (HP:0008921)2.65043228
35Male pseudohermaphroditism (HP:0000037)2.46448035
36Recurrent otitis media (HP:0000403)2.41166584
37Gait imbalance (HP:0002141)2.40974594
38Medial flaring of the eyebrow (HP:0010747)2.39334374
39Abnormality of the renal medulla (HP:0100957)2.38668234
40Congenital primary aphakia (HP:0007707)2.37791296
41Fibular hypoplasia (HP:0003038)2.34947867
42Preaxial hand polydactyly (HP:0001177)2.28333652
43Anencephaly (HP:0002323)2.24250656
44Facial cleft (HP:0002006)2.23127274
45Abnormal rod and cone electroretinograms (HP:0008323)2.18294523
46Chronic otitis media (HP:0000389)2.16808331
47Tubular atrophy (HP:0000092)2.16522952
48Hyperactive renin-angiotensin system (HP:0000841)2.15693759
49Absent rod-and cone-mediated responses on ERG (HP:0007688)2.14787635
50Nephrogenic diabetes insipidus (HP:0009806)2.09955579
51Sclerocornea (HP:0000647)2.09173166
52Atelectasis (HP:0100750)2.08902908
53Abnormality of abdominal situs (HP:0011620)2.04640065
54Abdominal situs inversus (HP:0003363)2.04640065
55Concave nail (HP:0001598)2.01487169
56Abnormality of permanent molar morphology (HP:0011071)2.00624408
57Abnormality of the dental root (HP:0006486)2.00624408
58Taurodontia (HP:0000679)2.00624408
59Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.2188216
60Abnormal respiratory motile cilium physiology (HP:0012261)12.1415887
61Abnormal ciliary motility (HP:0012262)12.0243543
62Rhinitis (HP:0012384)10.6295491
63Decreased circulating renin level (HP:0003351)1.97972892
64Genital tract atresia (HP:0001827)1.96897994
65Stage 5 chronic kidney disease (HP:0003774)1.96520004
66Infertility (HP:0000789)1.92845723
67Asplenia (HP:0001746)1.88715398
68Abnormality of molar (HP:0011077)1.85400189
69Abnormality of molar morphology (HP:0011070)1.85400189
70Bronchomalacia (HP:0002780)1.83417810
71Abnormality of macular pigmentation (HP:0008002)1.82689948
72Abnormality of the dental pulp (HP:0006479)1.82472876
73Postaxial hand polydactyly (HP:0001162)1.78737630
7411 pairs of ribs (HP:0000878)1.78340113
75Tubulointerstitial abnormality (HP:0001969)1.74204823
76Renal salt wasting (HP:0000127)1.73139769
77Polyuria (HP:0000103)1.72388987
78Aplasia/Hypoplasia of the spleen (HP:0010451)1.71603738
79Hypotelorism (HP:0000601)1.71482735
80Vaginal atresia (HP:0000148)1.69522246
81Acute necrotizing encephalopathy (HP:0006965)1.64615617
82Congenital stationary night blindness (HP:0007642)1.64199992
83Decreased central vision (HP:0007663)1.63563944
84Poor coordination (HP:0002370)1.62917102
85Furrowed tongue (HP:0000221)1.62515403
86Abnormality of secondary sexual hair (HP:0009888)1.61422512
87Abnormality of the axillary hair (HP:0100134)1.61422512
88Hypokalemic alkalosis (HP:0001949)1.60813244
89Retinitis pigmentosa (HP:0000510)1.60233464
90Ketoacidosis (HP:0001993)1.59542196
91Mitochondrial inheritance (HP:0001427)1.59514313
92Type II lissencephaly (HP:0007260)1.58410454
93Polydipsia (HP:0001959)1.58287859
94Abnormal drinking behavior (HP:0030082)1.58287859
95Hyperventilation (HP:0002883)1.57596094
96Abolished electroretinogram (ERG) (HP:0000550)1.55967617
97Progressive macrocephaly (HP:0004481)1.55399628
98Narrow forehead (HP:0000341)1.55014876
99Hyperaldosteronism (HP:0000859)1.52147906
100Bony spicule pigmentary retinopathy (HP:0007737)1.51394125
101Tubulointerstitial fibrosis (HP:0005576)1.51319685
102Abnormality of the fetal cardiovascular system (HP:0010948)1.50308206
103Abnormal umbilical cord blood vessels (HP:0011403)1.50308206
104Single umbilical artery (HP:0001195)1.50308206
105Stomatitis (HP:0010280)1.49564413
106Increased CSF lactate (HP:0002490)1.48502527
107Large for gestational age (HP:0001520)1.47581174
108Ectopic anus (HP:0004397)1.47407841
109Back pain (HP:0003418)1.47230643
110Methylmalonic acidemia (HP:0002912)1.46121538
111Ketosis (HP:0001946)1.44489657
112Abnormality of renin-angiotensin system (HP:0000847)1.43259054
113Prominent nasal bridge (HP:0000426)1.42323292
114Oculomotor apraxia (HP:0000657)1.42305047
115Adrenal hypoplasia (HP:0000835)1.41992789
116Aplasia/Hypoplasia of the fibula (HP:0006492)1.41306246
117Aganglionic megacolon (HP:0002251)1.40932273
118Absent speech (HP:0001344)1.40163242
119Abnormality of renal excretion (HP:0011036)1.39205066
120Methylmalonic aciduria (HP:0012120)1.38527762
1213-Methylglutaconic aciduria (HP:0003535)1.38340182
122Multicystic kidney dysplasia (HP:0000003)1.37733277
123Recurrent bronchitis (HP:0002837)1.37097961
124Broad distal phalanx of finger (HP:0009836)1.36939091
125Missing ribs (HP:0000921)1.36140860
126Acute encephalopathy (HP:0006846)1.36103570
127Hypoplastic scapulae (HP:0000882)1.35723047
128Aplasia/Hypoplasia of the scapulae (HP:0006713)1.35723047
129Aplasia/Hypoplasia of the lens (HP:0008063)1.35235855
130Disproportionate short-trunk short stature (HP:0003521)1.34837028
131Attenuation of retinal blood vessels (HP:0007843)1.33859357
132Short nail (HP:0001799)1.33766112
133Nephropathy (HP:0000112)1.32725085
134Abnormality of the renal cortex (HP:0011035)1.31219629
135Omphalocele (HP:0001539)1.27132886
136Polycystic kidney dysplasia (HP:0000113)1.25285360
137Abnormal connection of the cardiac segments (HP:0011545)1.24766342
138Abnormal ventriculo-arterial connection (HP:0011563)1.24766342
139Transposition of the great arteries (HP:0001669)1.24766342
140Male infertility (HP:0003251)1.20698773

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK159.06413405
2PNCK6.84542700
3FRK5.50456181
4MST44.39547918
5MAP2K22.63013154
6WNK32.33420660
7GRK12.32422833
8VRK12.25671810
9MAP4K22.20472107
10WEE12.08758093
11NLK2.00214553
12PINK11.96101477
13ACVR1B1.95100612
14WNK41.88793599
15TRIM281.85683343
16MAPKAPK31.81565268
17BMPR1B1.79686199
18TLK11.73103328
19CASK1.70927674
20NUAK11.65986206
21CAMKK21.61788992
22ADRBK21.57271352
23CDK31.55337245
24DAPK21.55298941
25EPHA21.54322243
26INSRR1.51327674
27STK391.39968270
28STK38L1.39265443
29NTRK21.30865489
30RPS6KA21.30670653
31PAK21.28716270
32BRSK21.20543643
33MKNK21.18058237
34GSK3A1.16451455
35PRKCI1.15391731
36OXSR11.14985277
37TEC1.14755428
38SIK11.12557571
39STK101.11730177
40MAPK131.08607737
41MAPKAPK51.07206938
42ERBB31.06436278
43DYRK31.06223329
44FER1.05880138
45NME11.02965060
46CSNK1G11.01694806
47ROCK20.99013767
48FES0.97054050
49SGK20.95330641
50CDK80.92614398
51DYRK20.92301264
52DYRK1A0.89367395
53STK30.88973509
54STK240.88924593
55MYLK0.88449793
56FGFR20.88341208
57ITK0.87704209
58TNIK0.87333458
59AURKA0.86634672
60MUSK0.86457628
61VRK20.85011149
62ROCK10.84697143
63BCR0.84138538
64SGK2230.83975446
65SGK4940.83975446
66BCKDK0.83260188
67RPS6KC10.81865067
68RPS6KL10.81865067
69TNK20.80571950
70PRKCG0.73231828
71MAP3K40.72513657
72RIPK40.72260233
73CAMKK10.70736058
74RPS6KA60.67366803
75IRAK10.65768964
76MAP2K60.64049500
77MAP3K30.63767818
78TTK0.63538450
79PLK20.62649975
80MAPK120.62563965
81IRAK30.62531412
82LRRK20.60772786
83CSNK1G20.60465264
84MARK10.55355734
85RPS6KA50.55300631
86LATS10.53977590
87CAMK2B0.53227230
88ERBB20.52508456
89MAPKAPK20.52483575
90PRKCE0.52284268
91PDK20.52218479
92TIE10.51704697
93EIF2AK30.51487767
94MAP2K70.51228592
95CCNB10.50558022
96ADRBK10.48711788
97MKNK10.47270085
98PLK30.46801015
99PAK30.46325262
100MAPK40.46309309
101MAPK70.45469451
102TXK0.44967161
103SGK30.44602961
104PTK2B0.43729828
105PRKACA0.43452959
106PKN10.42414538
107MAP2K10.40777087
108NEK60.40523615
109NTRK30.40513532
110PLK10.40318099
111IKBKB0.39666719
112BRSK10.39351669
113CSNK1G30.39270779
114GRK50.38946772
115PIM20.38801652
116LMTK20.38279130
117STK380.37791937
118PRKCZ0.37449501
119BTK0.36783597
120CAMK2A0.36728887
121PRKG10.35428978
122CSNK1A1L0.34440059
123EPHB10.34386003
124PBK0.33536571
125TRPM70.33146757
126MAP3K120.32824100
127EPHA30.32812867
128STK110.32736505
129MAPK30.31481740
130PHKG10.31433743
131PHKG20.31433743
132DAPK10.31151749
133TAOK10.30607533
134HIPK20.30162884
135ABL10.28850846
136GRK70.28415398
137CSNK1A10.27616567
138CSNK1E0.27579819
139PRKACG0.27523439
140MAP3K20.27349418
141MAPK90.27263936
142PRKAA20.26815895
143STK160.26649813
144YES10.26514067
145LATS20.25956327
146ZAK0.25530252
147CSK0.25511368
148MINK10.25275688
149PRKCA0.24736317
150PRKCQ0.23975082
151RPS6KA40.23207619
152BMPR20.22815462

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.39583353
2Huntingtons disease_Homo sapiens_hsa050163.52857432
3Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.91298173
4Histidine metabolism_Homo sapiens_hsa003402.90175134
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.88543612
6Caffeine metabolism_Homo sapiens_hsa002322.82466534
7Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.52105503
8Circadian rhythm_Homo sapiens_hsa047102.40083851
9Linoleic acid metabolism_Homo sapiens_hsa005912.35129011
10beta-Alanine metabolism_Homo sapiens_hsa004102.23855349
11Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.21664840
12Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.13367604
13Maturity onset diabetes of the young_Homo sapiens_hsa049502.10637844
14Oxidative phosphorylation_Homo sapiens_hsa001902.01289308
15Vitamin B6 metabolism_Homo sapiens_hsa007501.97759817
16Butanoate metabolism_Homo sapiens_hsa006501.88786802
17Gastric acid secretion_Homo sapiens_hsa049711.79910723
18Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.78386683
19Nicotine addiction_Homo sapiens_hsa050331.77838455
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.73110446
21GABAergic synapse_Homo sapiens_hsa047271.67039444
22PPAR signaling pathway_Homo sapiens_hsa033201.66483865
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.57467448
24Propanoate metabolism_Homo sapiens_hsa006401.55311521
25Tryptophan metabolism_Homo sapiens_hsa003801.52431094
26Tyrosine metabolism_Homo sapiens_hsa003501.50261159
27Alzheimers disease_Homo sapiens_hsa050101.49417086
28Fatty acid elongation_Homo sapiens_hsa000621.49265914
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.49175676
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.47864763
31Retinol metabolism_Homo sapiens_hsa008301.46397663
32Amphetamine addiction_Homo sapiens_hsa050311.45781576
33Parkinsons disease_Homo sapiens_hsa050121.44708027
34Chemical carcinogenesis_Homo sapiens_hsa052041.44129867
35Phototransduction_Homo sapiens_hsa047441.40862544
36Glutathione metabolism_Homo sapiens_hsa004801.33618147
37Olfactory transduction_Homo sapiens_hsa047401.32355151
38Phenylalanine metabolism_Homo sapiens_hsa003601.30664428
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.29325865
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.26709361
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.23264204
42Insulin secretion_Homo sapiens_hsa049111.22629856
43Cocaine addiction_Homo sapiens_hsa050301.20752847
44Regulation of autophagy_Homo sapiens_hsa041401.19895746
45Homologous recombination_Homo sapiens_hsa034401.18877701
46Taste transduction_Homo sapiens_hsa047421.18790826
47Circadian entrainment_Homo sapiens_hsa047131.15974061
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.14384687
49Fatty acid degradation_Homo sapiens_hsa000711.12140664
50Glutamatergic synapse_Homo sapiens_hsa047241.11236352
51RNA polymerase_Homo sapiens_hsa030201.10420438
52Cardiac muscle contraction_Homo sapiens_hsa042601.07707284
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.07109197
54Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.06803359
55Selenocompound metabolism_Homo sapiens_hsa004501.04314269
56Sulfur metabolism_Homo sapiens_hsa009201.03731618
57Arginine and proline metabolism_Homo sapiens_hsa003301.01355024
58Protein export_Homo sapiens_hsa030600.99155008
59Serotonergic synapse_Homo sapiens_hsa047260.97215848
60Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.96764185
61Prion diseases_Homo sapiens_hsa050200.96509757
62Fanconi anemia pathway_Homo sapiens_hsa034600.94895067
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.94644584
64Calcium signaling pathway_Homo sapiens_hsa040200.93820386
65Basal transcription factors_Homo sapiens_hsa030220.93691948
66Estrogen signaling pathway_Homo sapiens_hsa049150.91574560
67Ovarian steroidogenesis_Homo sapiens_hsa049130.90707323
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.90265557
69Morphine addiction_Homo sapiens_hsa050320.88930272
70Rheumatoid arthritis_Homo sapiens_hsa053230.88827817
71Thyroid hormone synthesis_Homo sapiens_hsa049180.88675985
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88479596
73Ether lipid metabolism_Homo sapiens_hsa005650.88206069
74Proteasome_Homo sapiens_hsa030500.87000008
75Type I diabetes mellitus_Homo sapiens_hsa049400.86993693
76Salivary secretion_Homo sapiens_hsa049700.84142628
77Renin secretion_Homo sapiens_hsa049240.83470465
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.81303520
79cAMP signaling pathway_Homo sapiens_hsa040240.79018583
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.78017429
81Folate biosynthesis_Homo sapiens_hsa007900.75877785
82Wnt signaling pathway_Homo sapiens_hsa043100.75445081
83Purine metabolism_Homo sapiens_hsa002300.73635272
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.73485678
85Arachidonic acid metabolism_Homo sapiens_hsa005900.70216876
86Glycerolipid metabolism_Homo sapiens_hsa005610.69650091
87Hedgehog signaling pathway_Homo sapiens_hsa043400.69297082
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.69197521
89Dilated cardiomyopathy_Homo sapiens_hsa054140.69189932
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.68883703
91Non-homologous end-joining_Homo sapiens_hsa034500.68574876
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.67872139
93Collecting duct acid secretion_Homo sapiens_hsa049660.67531833
94Mineral absorption_Homo sapiens_hsa049780.67228388
95Basal cell carcinoma_Homo sapiens_hsa052170.65645787
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.62840864
97Autoimmune thyroid disease_Homo sapiens_hsa053200.62319389
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61398605
99Sphingolipid metabolism_Homo sapiens_hsa006000.60919244
100Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60913312
101Phagosome_Homo sapiens_hsa041450.59622066
102Vascular smooth muscle contraction_Homo sapiens_hsa042700.59611033
103Antigen processing and presentation_Homo sapiens_hsa046120.58538687
104Primary bile acid biosynthesis_Homo sapiens_hsa001200.57951640
105Lysosome_Homo sapiens_hsa041420.57119655
106Steroid biosynthesis_Homo sapiens_hsa001000.57086642
107Drug metabolism - other enzymes_Homo sapiens_hsa009830.55860412
108Aldosterone synthesis and secretion_Homo sapiens_hsa049250.54680839
109Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53956454
110Peroxisome_Homo sapiens_hsa041460.53651127
111Oxytocin signaling pathway_Homo sapiens_hsa049210.53393196
112Allograft rejection_Homo sapiens_hsa053300.53042970
113Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.52460272
114Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48013847
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47977906
116Bile secretion_Homo sapiens_hsa049760.47458175
117Hematopoietic cell lineage_Homo sapiens_hsa046400.46688648
118Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.45953153
119Hippo signaling pathway_Homo sapiens_hsa043900.45029252
120GnRH signaling pathway_Homo sapiens_hsa049120.44710726
121Melanogenesis_Homo sapiens_hsa049160.43935251
122cGMP-PKG signaling pathway_Homo sapiens_hsa040220.43912603
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41601591
124Starch and sucrose metabolism_Homo sapiens_hsa005000.41451988
125Fatty acid metabolism_Homo sapiens_hsa012120.41360006
126ABC transporters_Homo sapiens_hsa020100.40027081
127RNA degradation_Homo sapiens_hsa030180.38813873
128Pyrimidine metabolism_Homo sapiens_hsa002400.38425210
129Nucleotide excision repair_Homo sapiens_hsa034200.38142391
130Asthma_Homo sapiens_hsa053100.37868133
131Malaria_Homo sapiens_hsa051440.37744236
132ECM-receptor interaction_Homo sapiens_hsa045120.37062860
133Gap junction_Homo sapiens_hsa045400.36705398
134Metabolic pathways_Homo sapiens_hsa011000.36190063
135Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36101912
136Nitrogen metabolism_Homo sapiens_hsa009100.35679219
137Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35381834
138Complement and coagulation cascades_Homo sapiens_hsa046100.34312865
139Dopaminergic synapse_Homo sapiens_hsa047280.32863908
140Vitamin digestion and absorption_Homo sapiens_hsa049770.31725914
141Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.31509183
142Dorso-ventral axis formation_Homo sapiens_hsa043200.31308734
143N-Glycan biosynthesis_Homo sapiens_hsa005100.30395956
144Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.28256977
145Tight junction_Homo sapiens_hsa045300.27960376
146Intestinal immune network for IgA production_Homo sapiens_hsa046720.26307832

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