

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | axonemal dynein complex assembly (GO:0070286) | 9.41869561 |
| 2 | sperm-egg recognition (GO:0035036) | 9.31172858 |
| 3 | male meiosis (GO:0007140) | 9.07654111 |
| 4 | binding of sperm to zona pellucida (GO:0007339) | 8.93296783 |
| 5 | multicellular organism reproduction (GO:0032504) | 8.86280141 |
| 6 | synaptonemal complex organization (GO:0070193) | 8.85250645 |
| 7 | acrosome reaction (GO:0007340) | 8.79150729 |
| 8 | acrosome assembly (GO:0001675) | 8.66959977 |
| 9 | synaptonemal complex assembly (GO:0007130) | 8.58028173 |
| 10 | spermatid development (GO:0007286) | 8.45527731 |
| 11 | epithelial cilium movement (GO:0003351) | 8.41359189 |
| 12 | cell-cell recognition (GO:0009988) | 8.29938824 |
| 13 | motile cilium assembly (GO:0044458) | 8.19464131 |
| 14 | plasma membrane fusion (GO:0045026) | 8.00566511 |
| 15 | cell wall macromolecule metabolic process (GO:0044036) | 7.82832029 |
| 16 | cell wall macromolecule catabolic process (GO:0016998) | 7.82832029 |
| 17 | DNA methylation involved in gamete generation (GO:0043046) | 7.51027093 |
| 18 | cilium movement (GO:0003341) | 7.38512548 |
| 19 | reproduction (GO:0000003) | 7.34207020 |
| 20 | regulation of cilium movement (GO:0003352) | 7.16257287 |
| 21 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 7.05368226 |
| 22 | tachykinin receptor signaling pathway (GO:0007217) | 6.92041837 |
| 23 | male meiosis I (GO:0007141) | 6.69602329 |
| 24 | DNA synthesis involved in DNA repair (GO:0000731) | 6.62273392 |
| 25 | negative regulation of inclusion body assembly (GO:0090084) | 6.15932406 |
| 26 | single fertilization (GO:0007338) | 6.10881022 |
| 27 | chromosome organization involved in meiosis (GO:0070192) | 5.96115348 |
| 28 | meiotic nuclear division (GO:0007126) | 5.85001792 |
| 29 | spermatogenesis (GO:0007283) | 5.72358823 |
| 30 | fertilization (GO:0009566) | 5.70737590 |
| 31 | male gamete generation (GO:0048232) | 5.70601804 |
| 32 | meiosis I (GO:0007127) | 5.62049337 |
| 33 | microtubule depolymerization (GO:0007019) | 5.61052824 |
| 34 | meiotic chromosome segregation (GO:0045132) | 5.44393233 |
| 35 | gamete generation (GO:0007276) | 5.30065336 |
| 36 | regulation of inclusion body assembly (GO:0090083) | 5.29603530 |
| 37 | germ cell development (GO:0007281) | 5.26449034 |
| 38 | sperm capacitation (GO:0048240) | 5.00068961 |
| 39 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 4.99534208 |
| 40 | regulation of meiosis I (GO:0060631) | 4.93828399 |
| 41 | resolution of meiotic recombination intermediates (GO:0000712) | 4.79710005 |
| 42 | meiotic cell cycle (GO:0051321) | 4.77585311 |
| 43 | positive regulation of digestive system process (GO:0060456) | 4.65829831 |
| 44 | ventricular system development (GO:0021591) | 4.61394282 |
| 45 | microtubule severing (GO:0051013) | 4.48489203 |
| 46 | positive regulation of meiosis (GO:0045836) | 4.42226576 |
| 47 | gene silencing by RNA (GO:0031047) | 4.40385182 |
| 48 | regulation of microtubule-based movement (GO:0060632) | 4.33998068 |
| 49 | seminiferous tubule development (GO:0072520) | 4.30837526 |
| 50 | multicellular organismal reproductive process (GO:0048609) | 4.15417404 |
| 51 | meiotic cell cycle process (GO:1903046) | 4.15382444 |
| 52 | organic cation transport (GO:0015695) | 4.15023783 |
| 53 | positive regulation of meiotic cell cycle (GO:0051446) | 4.12147706 |
| 54 | calcium ion-dependent exocytosis (GO:0017156) | 4.11535363 |
| 55 | cell recognition (GO:0008037) | 4.01554244 |
| 56 | chromosome condensation (GO:0030261) | 3.95023447 |
| 57 | DNA packaging (GO:0006323) | 3.94105210 |
| 58 | left/right pattern formation (GO:0060972) | 3.83674615 |
| 59 | chaperone-mediated protein complex assembly (GO:0051131) | 3.77036804 |
| 60 | protein localization to cilium (GO:0061512) | 3.70460663 |
| 61 | female gamete generation (GO:0007292) | 3.66153763 |
| 62 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.64668083 |
| 63 | protein polyglutamylation (GO:0018095) | 3.61778808 |
| 64 | response to pheromone (GO:0019236) | 3.59690602 |
| 65 | genitalia morphogenesis (GO:0035112) | 3.58678915 |
| 66 | spermatid nucleus differentiation (GO:0007289) | 3.55327364 |
| 67 | regulation of spindle checkpoint (GO:0090231) | 3.43013281 |
| 68 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.42986244 |
| 69 | detection of light stimulus involved in visual perception (GO:0050908) | 3.42986244 |
| 70 | axoneme assembly (GO:0035082) | 3.41419976 |
| 71 | histone H3-K9 demethylation (GO:0033169) | 3.40902303 |
| 72 | regulation of centriole replication (GO:0046599) | 3.39899525 |
| 73 | DNA alkylation (GO:0006305) | 3.36890043 |
| 74 | DNA methylation (GO:0006306) | 3.36890043 |
| 75 | mitotic sister chromatid cohesion (GO:0007064) | 3.35127420 |
| 76 | synapsis (GO:0007129) | 3.32641797 |
| 77 | regulation of meiotic cell cycle (GO:0051445) | 3.32381159 |
| 78 | negative regulation of organelle assembly (GO:1902116) | 3.31361821 |
| 79 | multicellular organismal development (GO:0007275) | 3.29085249 |
| 80 | gene silencing (GO:0016458) | 3.26868041 |
| 81 | intraciliary transport (GO:0042073) | 3.25771767 |
| 82 | cochlea development (GO:0090102) | 3.24580398 |
| 83 | nuclear pore complex assembly (GO:0051292) | 3.20312780 |
| 84 | centriole replication (GO:0007099) | 3.19964649 |
| 85 | histone exchange (GO:0043486) | 3.15981290 |
| 86 | regulation of DNA endoreduplication (GO:0032875) | 3.13422976 |
| 87 | response to histamine (GO:0034776) | 3.13227755 |
| 88 | nucleus organization (GO:0006997) | 3.09238352 |
| 89 | establishment of protein localization to Golgi (GO:0072600) | 3.05024960 |
| 90 | single strand break repair (GO:0000012) | 3.03608206 |
| 91 | protein refolding (GO:0042026) | 2.99920231 |
| 92 | sister chromatid cohesion (GO:0007062) | 2.99678918 |
| 93 | brain morphogenesis (GO:0048854) | 2.96147948 |
| 94 | microtubule-based movement (GO:0007018) | 2.95189617 |
| 95 | protein localization to chromosome, centromeric region (GO:0071459) | 2.95106173 |
| 96 | auditory receptor cell stereocilium organization (GO:0060088) | 2.94485965 |
| 97 | proteasome assembly (GO:0043248) | 2.94292570 |
| 98 | glycerol ether metabolic process (GO:0006662) | 2.93957168 |
| 99 | protein targeting to Golgi (GO:0000042) | 2.92389950 |
| 100 | photoreceptor cell maintenance (GO:0045494) | 2.91344984 |
| 101 | histone H2A acetylation (GO:0043968) | 2.89307236 |
| 102 | regulation of histone H3-K9 methylation (GO:0051570) | 2.88716090 |
| 103 | microtubule polymerization or depolymerization (GO:0031109) | 2.88439916 |
| 104 | fucose catabolic process (GO:0019317) | 2.86774759 |
| 105 | L-fucose metabolic process (GO:0042354) | 2.86774759 |
| 106 | L-fucose catabolic process (GO:0042355) | 2.86774759 |
| 107 | nuclear pore organization (GO:0006999) | 2.85392073 |
| 108 | histone H3-K36 demethylation (GO:0070544) | 2.82888185 |
| 109 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.81310204 |
| 110 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.81310204 |
| 111 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.79154746 |
| 112 | cilium organization (GO:0044782) | 2.78616597 |
| 113 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.75637118 |
| 114 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.72577439 |
| 115 | cellular ketone body metabolic process (GO:0046950) | 2.72503742 |
| 116 | ether metabolic process (GO:0018904) | 2.70238244 |
| 117 | sex differentiation (GO:0007548) | 2.70160058 |
| 118 | coenzyme catabolic process (GO:0009109) | 2.68199874 |
| 119 | polyol catabolic process (GO:0046174) | 2.67200588 |
| 120 | oogenesis (GO:0048477) | 2.64498464 |
| 121 | negative regulation of gene silencing (GO:0060969) | 2.64024447 |
| 122 | cilium morphogenesis (GO:0060271) | 2.63729504 |
| 123 | protein K11-linked deubiquitination (GO:0035871) | 2.63678692 |
| 124 | cilium assembly (GO:0042384) | 2.63628883 |
| 125 | DNA methylation or demethylation (GO:0044728) | 2.62740418 |
| 126 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.60890594 |
| 127 | limb development (GO:0060173) | 2.60387171 |
| 128 | appendage development (GO:0048736) | 2.60387171 |
| 129 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.59747137 |
| 130 | regulation of meiosis (GO:0040020) | 2.59100974 |
| 131 | reciprocal meiotic recombination (GO:0007131) | 2.58189979 |
| 132 | reciprocal DNA recombination (GO:0035825) | 2.58189979 |
| 133 | oocyte development (GO:0048599) | 2.57441970 |
| 134 | protein K6-linked ubiquitination (GO:0085020) | 2.56903346 |
| 135 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.56450535 |
| 136 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.56321786 |
| 137 | centriole assembly (GO:0098534) | 2.51021312 |
| 138 | protein localization to Golgi apparatus (GO:0034067) | 2.50411997 |
| 139 | indolalkylamine catabolic process (GO:0046218) | 2.49764905 |
| 140 | piRNA metabolic process (GO:0034587) | 11.1614998 |
| 141 | cilium or flagellum-dependent cell motility (GO:0001539) | 10.7981685 |
| 142 | fusion of sperm to egg plasma membrane (GO:0007342) | 10.4718244 |
| 143 | sperm motility (GO:0030317) | 10.4131107 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.35803005 |
| 2 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.24260583 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.09315295 |
| 4 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.06971647 |
| 5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.99078229 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.79568419 |
| 7 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 2.64257531 |
| 8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.36936631 |
| 9 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.29858504 |
| 10 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 2.29607528 |
| 11 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.29069324 |
| 12 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.20658659 |
| 13 | BCAT_22108803_ChIP-Seq_LS180_Human | 2.17165606 |
| 14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.17073278 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.12761643 |
| 16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.09049701 |
| 17 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.05600976 |
| 18 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.01627179 |
| 19 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 11.3586546 |
| 20 | P300_19829295_ChIP-Seq_ESCs_Human | 1.98851173 |
| 21 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.98605160 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.95833634 |
| 23 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.89210614 |
| 24 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.86491639 |
| 25 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.85149462 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.82367587 |
| 27 | STAT3_23295773_ChIP-Seq_U87_Human | 1.81289670 |
| 28 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.81167623 |
| 29 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.78592656 |
| 30 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.77553536 |
| 31 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.75349418 |
| 32 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.74647501 |
| 33 | TCF4_23295773_ChIP-Seq_U87_Human | 1.70949748 |
| 34 | VDR_22108803_ChIP-Seq_LS180_Human | 1.67924137 |
| 35 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.63482605 |
| 36 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.63234161 |
| 37 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.59453890 |
| 38 | EWS_26573619_Chip-Seq_HEK293_Human | 1.57235969 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.56236254 |
| 40 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.55171233 |
| 41 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.54646983 |
| 42 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.51065288 |
| 43 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.49536782 |
| 44 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.49431875 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.47683996 |
| 46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.47415662 |
| 47 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.47176155 |
| 48 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.47176155 |
| 49 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.46824098 |
| 50 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.46529199 |
| 51 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.46152473 |
| 52 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.45505388 |
| 53 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.44892647 |
| 54 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.42564131 |
| 55 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.42385086 |
| 56 | * FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.42005110 |
| 57 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.41666366 |
| 58 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.39207669 |
| 59 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.38544057 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.36943794 |
| 61 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.36729315 |
| 62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.36254653 |
| 63 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33918251 |
| 64 | * ERA_21632823_ChIP-Seq_H3396_Human | 1.31877337 |
| 65 | FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.31256631 |
| 66 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.31058475 |
| 67 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.29978966 |
| 68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.29608173 |
| 69 | * FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.29142833 |
| 70 | * FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.29142833 |
| 71 | GATA3_21867929_ChIP-Seq_CD8_Mouse | 1.28664257 |
| 72 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.28196548 |
| 73 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.27736423 |
| 74 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.26878513 |
| 75 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.26460880 |
| 76 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.25108878 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.24514452 |
| 78 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.23233635 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.21253048 |
| 80 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.20917859 |
| 81 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.20605254 |
| 82 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20258732 |
| 83 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.20200724 |
| 84 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.19228692 |
| 85 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.18230279 |
| 86 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.17480412 |
| 87 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.17033825 |
| 88 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.16469177 |
| 89 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.16066078 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14541540 |
| 91 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.13125691 |
| 92 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.11871958 |
| 93 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11342234 |
| 94 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08684342 |
| 95 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.08628214 |
| 96 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.08087602 |
| 97 | GATA3_26560356_Chip-Seq_TH1_Human | 1.07665835 |
| 98 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.07260391 |
| 99 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.05412856 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05405243 |
| 101 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.03010927 |
| 102 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02707843 |
| 103 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02456350 |
| 104 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02365469 |
| 105 | * P53_21459846_ChIP-Seq_SAOS-2_Human | 1.02299392 |
| 106 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.01850067 |
| 107 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.01848451 |
| 108 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.01231929 |
| 109 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.99667970 |
| 110 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.99506835 |
| 111 | * AR_20517297_ChIP-Seq_VCAP_Human | 0.99253235 |
| 112 | LUZP1_20508642_ChIP-Seq_ESCs_Mouse | 0.98916389 |
| 113 | RUNX1_26923725_Chip-Seq_HPCs_Mouse | 0.98651079 |
| 114 | SPI1_26923725_Chip-Seq_HPCs_Mouse | 0.98620863 |
| 115 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.97528298 |
| 116 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96398398 |
| 117 | * CDX2_22108803_ChIP-Seq_LS180_Human | 0.96150959 |
| 118 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95358693 |
| 119 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.95358693 |
| 120 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.95071088 |
| 121 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.94349464 |
| 122 | KDM2B_26808549_Chip-Seq_REH_Human | 0.93887506 |
| 123 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.93742018 |
| 124 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93742018 |
| 125 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.93537888 |
| 126 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.93038397 |
| 127 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92570234 |
| 128 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.92524856 |
| 129 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.92351603 |
| 130 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.92183410 |
| 131 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.91946073 |
| 132 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.91344812 |
| 133 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.90090546 |
| 134 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.89411658 |
| 135 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.89340657 |
| 136 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.87381073 |
| 137 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.86259155 |
| 138 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.86007447 |
| 139 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.85798819 |
| 140 | GF1_26923725_Chip-Seq_HPCs_Mouse | 0.85304260 |
| 141 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.85167808 |
| 142 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.84818919 |
| 143 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.84629848 |
| 144 | LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.84543200 |
| 145 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.83319105 |
| 146 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.83118890 |
| 147 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.82200089 |
| 148 | TBL1_22424771_ChIP-Seq_293T_Human | 0.81700407 |
| 149 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.81502365 |
| 150 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.80619251 |
| 151 | NFYB_21822215_ChIP-Seq_K562_Human | 0.80539662 |
| 152 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.80433344 |
| 153 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.80100441 |
| 154 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.79485157 |
| 155 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.79449848 |
| 156 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.78328094 |
| 157 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.78159978 |
| 158 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.77905545 |
| 159 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.77091488 |
| 160 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.75800690 |
| 161 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.75758992 |
| 162 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.75694026 |
| 163 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.75423848 |
| 164 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.75266491 |
| 165 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.75200459 |
| 166 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.75141631 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 6.22224812 |
| 2 | MP0003698_abnormal_male_reproductive | 5.42833116 |
| 3 | MP0001929_abnormal_gametogenesis | 5.40355282 |
| 4 | MP0002210_abnormal_sex_determination | 4.04039394 |
| 5 | MP0001145_abnormal_male_reproductive | 3.34402245 |
| 6 | MP0002161_abnormal_fertility/fecundity | 3.16345290 |
| 7 | MP0000653_abnormal_sex_gland | 3.01297725 |
| 8 | MP0001501_abnormal_sleep_pattern | 2.97945332 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.88094344 |
| 10 | MP0010094_abnormal_chromosome_stability | 2.38513515 |
| 11 | MP0002160_abnormal_reproductive_system | 2.34592905 |
| 12 | MP0003195_calcinosis | 2.24970471 |
| 13 | MP0003646_muscle_fatigue | 2.12069535 |
| 14 | MP0008057_abnormal_DNA_replication | 2.06324581 |
| 15 | MP0008995_early_reproductive_senescence | 2.03069997 |
| 16 | MP0003111_abnormal_nucleus_morphology | 2.01789628 |
| 17 | MP0006276_abnormal_autonomic_nervous | 2.01748844 |
| 18 | MP0005410_abnormal_fertilization | 12.3819028 |
| 19 | MP0008058_abnormal_DNA_repair | 1.88014757 |
| 20 | MP0005645_abnormal_hypothalamus_physiol | 1.86640036 |
| 21 | MP0000569_abnormal_digit_pigmentation | 1.81379310 |
| 22 | MP0003786_premature_aging | 1.61387762 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.61060808 |
| 24 | MP0001486_abnormal_startle_reflex | 1.55033218 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.51725651 |
| 26 | MP0009745_abnormal_behavioral_response | 1.50574612 |
| 27 | MP0000383_abnormal_hair_follicle | 1.49158563 |
| 28 | MP0003878_abnormal_ear_physiology | 1.46787961 |
| 29 | MP0005377_hearing/vestibular/ear_phenot | 1.46787961 |
| 30 | MP0005646_abnormal_pituitary_gland | 1.43708955 |
| 31 | MP0005389_reproductive_system_phenotype | 1.42074497 |
| 32 | MP0005623_abnormal_meninges_morphology | 1.41891716 |
| 33 | MP0005670_abnormal_white_adipose | 1.40730928 |
| 34 | MP0002735_abnormal_chemical_nociception | 1.40682212 |
| 35 | MP0003077_abnormal_cell_cycle | 1.39988459 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.38773000 |
| 37 | MP0004043_abnormal_pH_regulation | 1.35526958 |
| 38 | MP0000678_abnormal_parathyroid_gland | 1.35359038 |
| 39 | MP0008007_abnormal_cellular_replicative | 1.20840469 |
| 40 | MP0009046_muscle_twitch | 1.19844370 |
| 41 | MP0004233_abnormal_muscle_weight | 1.18709862 |
| 42 | MP0010386_abnormal_urinary_bladder | 1.13705968 |
| 43 | MP0004147_increased_porphyrin_level | 1.10996850 |
| 44 | MP0004957_abnormal_blastocyst_morpholog | 1.10377342 |
| 45 | MP0003718_maternal_effect | 1.10352749 |
| 46 | MP0000631_abnormal_neuroendocrine_gland | 1.09359486 |
| 47 | MP0003879_abnormal_hair_cell | 1.09018307 |
| 48 | MP0005423_abnormal_somatic_nervous | 1.03950866 |
| 49 | MP0001963_abnormal_hearing_physiology | 1.03033894 |
| 50 | MP0010307_abnormal_tumor_latency | 1.01642643 |
| 51 | MP0002067_abnormal_sensory_capabilities | 1.01190788 |
| 52 | MP0002138_abnormal_hepatobiliary_system | 1.00873997 |
| 53 | MP0003699_abnormal_female_reproductive | 1.00779815 |
| 54 | MP0001485_abnormal_pinna_reflex | 1.00474183 |
| 55 | MP0001730_embryonic_growth_arrest | 1.00463629 |
| 56 | MP0008872_abnormal_physiological_respon | 1.00110710 |
| 57 | MP0002234_abnormal_pharynx_morphology | 0.96688312 |
| 58 | MP0002282_abnormal_trachea_morphology | 0.96439958 |
| 59 | MP0002184_abnormal_innervation | 0.93340597 |
| 60 | MP0001970_abnormal_pain_threshold | 0.92772247 |
| 61 | MP0005167_abnormal_blood-brain_barrier | 0.92019343 |
| 62 | MP0002733_abnormal_thermal_nociception | 0.89880493 |
| 63 | MP0001119_abnormal_female_reproductive | 0.89473569 |
| 64 | MP0002638_abnormal_pupillary_reflex | 0.88580766 |
| 65 | MP0002909_abnormal_adrenal_gland | 0.88009216 |
| 66 | MP0001764_abnormal_homeostasis | 0.87956224 |
| 67 | MP0008789_abnormal_olfactory_epithelium | 0.87898600 |
| 68 | MP0001984_abnormal_olfaction | 0.87380697 |
| 69 | MP0003123_paternal_imprinting | 0.87062557 |
| 70 | MP0004019_abnormal_vitamin_homeostasis | 0.85363161 |
| 71 | MP0005647_abnormal_sex_gland | 0.85299313 |
| 72 | MP0002876_abnormal_thyroid_physiology | 0.82866779 |
| 73 | MP0003315_abnormal_perineum_morphology | 0.82277381 |
| 74 | MP0000026_abnormal_inner_ear | 0.81246922 |
| 75 | MP0009780_abnormal_chondrocyte_physiolo | 0.81089079 |
| 76 | MP0002229_neurodegeneration | 0.79133021 |
| 77 | MP0001664_abnormal_digestion | 0.77757984 |
| 78 | MP0002557_abnormal_social/conspecific_i | 0.77166194 |
| 79 | MP0001727_abnormal_embryo_implantation | 0.76609821 |
| 80 | MP0004742_abnormal_vestibular_system | 0.76575859 |
| 81 | MP0008932_abnormal_embryonic_tissue | 0.76332370 |
| 82 | MP0005174_abnormal_tail_pigmentation | 0.76177441 |
| 83 | MP0002734_abnormal_mechanical_nocicepti | 0.76106282 |
| 84 | MP0005310_abnormal_salivary_gland | 0.75361672 |
| 85 | MP0003115_abnormal_respiratory_system | 0.74925420 |
| 86 | MP0006072_abnormal_retinal_apoptosis | 0.74864597 |
| 87 | MP0001529_abnormal_vocalization | 0.74488972 |
| 88 | MP0003937_abnormal_limbs/digits/tail_de | 0.74366182 |
| 89 | MP0003943_abnormal_hepatobiliary_system | 0.74353870 |
| 90 | MP0010678_abnormal_skin_adnexa | 0.74182631 |
| 91 | MP0004859_abnormal_synaptic_plasticity | 0.73947409 |
| 92 | MP0002095_abnormal_skin_pigmentation | 0.72948827 |
| 93 | MP0003183_abnormal_peptide_metabolism | 0.72044220 |
| 94 | MP0001324_abnormal_eye_pigmentation | 0.71186644 |
| 95 | MP0002064_seizures | 0.69027419 |
| 96 | MP0000015_abnormal_ear_pigmentation | 0.67522524 |
| 97 | MP0000358_abnormal_cell_content/ | 0.66453029 |
| 98 | MP0002102_abnormal_ear_morphology | 0.65986613 |
| 99 | MP0000647_abnormal_sebaceous_gland | 0.65977411 |
| 100 | MP0003136_yellow_coat_color | 0.65051560 |
| 101 | MP0001765_abnormal_ion_homeostasis | 0.64099618 |
| 102 | MP0000778_abnormal_nervous_system | 0.63615800 |
| 103 | MP0002084_abnormal_developmental_patter | 0.63333974 |
| 104 | MP0001672_abnormal_embryogenesis/_devel | 0.62806678 |
| 105 | MP0005380_embryogenesis_phenotype | 0.62806678 |
| 106 | MP0002928_abnormal_bile_duct | 0.61100267 |
| 107 | MP0002736_abnormal_nociception_after | 0.60414704 |
| 108 | MP0000350_abnormal_cell_proliferation | 0.59196586 |
| 109 | MP0002085_abnormal_embryonic_tissue | 0.57370883 |
| 110 | MP0003861_abnormal_nervous_system | 0.57262477 |
| 111 | MP0000639_abnormal_adrenal_gland | 0.56883228 |
| 112 | MP0004808_abnormal_hematopoietic_stem | 0.56435970 |
| 113 | MP0001440_abnormal_grooming_behavior | 0.55958132 |
| 114 | MP0001919_abnormal_reproductive_system | 0.55873786 |
| 115 | MP0001293_anophthalmia | 0.55596082 |
| 116 | MP0001697_abnormal_embryo_size | 0.54886199 |
| 117 | MP0001968_abnormal_touch/_nociception | 0.52451024 |
| 118 | MP0001545_abnormal_hematopoietic_system | 0.51394579 |
| 119 | MP0005397_hematopoietic_system_phenotyp | 0.51394579 |
| 120 | MP0002080_prenatal_lethality | 0.51393790 |
| 121 | MP0000313_abnormal_cell_death | 0.51145710 |
| 122 | MP0004133_heterotaxia | 0.50640506 |
| 123 | MP0003635_abnormal_synaptic_transmissio | 0.48221772 |
| 124 | MP0003329_amyloid_beta_deposits | 0.47459844 |
| 125 | MP0005551_abnormal_eye_electrophysiolog | 0.47274655 |
| 126 | MP0003936_abnormal_reproductive_system | 0.46371635 |
| 127 | MP0001661_extended_life_span | 0.46248581 |
| 128 | MP0002269_muscular_atrophy | 0.45957545 |
| 129 | MP0003787_abnormal_imprinting | 0.45957218 |
| 130 | MP0002572_abnormal_emotion/affect_behav | 0.44739520 |
| 131 | MP0005253_abnormal_eye_physiology | 0.44648824 |
| 132 | MP0000427_abnormal_hair_cycle | 0.44586839 |
| 133 | MP0002152_abnormal_brain_morphology | 0.44430559 |
| 134 | MP0003984_embryonic_growth_retardation | 0.43753405 |
| 135 | MP0008260_abnormal_autophagy | 0.43364452 |
| 136 | MP0002063_abnormal_learning/memory/cond | 0.43099718 |
| 137 | MP0003880_abnormal_central_pattern | 0.42277869 |
| 138 | MP0004197_abnormal_fetal_growth/weight/ | 0.41085734 |
| 139 | MP0003942_abnormal_urinary_system | 0.40931245 |
| 140 | MP0003121_genomic_imprinting | 0.40921608 |
| 141 | MP0002088_abnormal_embryonic_growth/wei | 0.40851829 |
| 142 | MP0009672_abnormal_birth_weight | 0.40796115 |
| 143 | MP0004036_abnormal_muscle_relaxation | 0.39179334 |
| 144 | MP0004270_analgesia | 0.38936037 |
| 145 | MP0004811_abnormal_neuron_physiology | 0.38935217 |
| 146 | MP0005391_vision/eye_phenotype | 0.37473873 |
| 147 | MP0009278_abnormal_bone_marrow | 0.35555165 |
| 148 | MP0003119_abnormal_digestive_system | 0.35440468 |
| 149 | MP0005395_other_phenotype | 0.34311417 |
| 150 | MP0002272_abnormal_nervous_system | 0.32260528 |
| 151 | MP0001849_ear_inflammation | 0.31648399 |
| 152 | MP0002169_no_abnormal_phenotype | 0.31442688 |
| 153 | MP0002873_normal_phenotype | 0.31057726 |
| 154 | MP0004084_abnormal_cardiac_muscle | 0.28558766 |
| 155 | MP0006035_abnormal_mitochondrial_morpho | 0.28093891 |
| 156 | MP0002086_abnormal_extraembryonic_tissu | 0.27701017 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal respiratory motile cilium physiology (HP:0012261) | 8.74810308 |
| 2 | Abnormal respiratory epithelium morphology (HP:0012253) | 8.32242322 |
| 3 | Abnormal respiratory motile cilium morphology (HP:0005938) | 8.32242322 |
| 4 | Rhinitis (HP:0012384) | 7.47529729 |
| 5 | Abnormal ciliary motility (HP:0012262) | 7.03169475 |
| 6 | Chronic bronchitis (HP:0004469) | 6.77397574 |
| 7 | Infertility (HP:0000789) | 6.68597361 |
| 8 | Nasal polyposis (HP:0100582) | 5.36478408 |
| 9 | Nephronophthisis (HP:0000090) | 4.49206820 |
| 10 | Bronchiectasis (HP:0002110) | 4.36878450 |
| 11 | Abnormality of macular pigmentation (HP:0008002) | 4.31548803 |
| 12 | Abnormality of the nasal mucosa (HP:0000433) | 4.30862872 |
| 13 | Male infertility (HP:0003251) | 4.28481524 |
| 14 | Bronchitis (HP:0012387) | 3.88306408 |
| 15 | Type II lissencephaly (HP:0007260) | 3.82693906 |
| 16 | Attenuation of retinal blood vessels (HP:0007843) | 3.79200825 |
| 17 | Oligodactyly (hands) (HP:0001180) | 3.77461885 |
| 18 | Abnormality of the lower motor neuron (HP:0002366) | 3.76743701 |
| 19 | Abnormal spermatogenesis (HP:0008669) | 3.67079617 |
| 20 | Volvulus (HP:0002580) | 3.60231402 |
| 21 | Gonadotropin excess (HP:0000837) | 3.49927193 |
| 22 | Decreased central vision (HP:0007663) | 3.46760063 |
| 23 | Abnormality of the renal medulla (HP:0100957) | 3.28381201 |
| 24 | Spontaneous abortion (HP:0005268) | 3.18566268 |
| 25 | Impulsivity (HP:0100710) | 3.14673398 |
| 26 | Pancreatic cysts (HP:0001737) | 3.11174074 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.97740679 |
| 28 | Molar tooth sign on MRI (HP:0002419) | 2.97740679 |
| 29 | Congenital stationary night blindness (HP:0007642) | 2.92786790 |
| 30 | Azoospermia (HP:0000027) | 2.87586170 |
| 31 | Recurrent otitis media (HP:0000403) | 2.86517742 |
| 32 | Amyotrophic lateral sclerosis (HP:0007354) | 2.79150997 |
| 33 | Chronic hepatic failure (HP:0100626) | 2.76437013 |
| 34 | Progressive inability to walk (HP:0002505) | 2.72655550 |
| 35 | Recurrent sinusitis (HP:0011108) | 2.72248582 |
| 36 | Retinal dysplasia (HP:0007973) | 2.72159561 |
| 37 | Tubulointerstitial nephritis (HP:0001970) | 2.71904345 |
| 38 | Severe visual impairment (HP:0001141) | 2.64799135 |
| 39 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.59123748 |
| 40 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.59123748 |
| 41 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.54145554 |
| 42 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.51989386 |
| 43 | Abnormality of alanine metabolism (HP:0010916) | 2.51989386 |
| 44 | Hyperalaninemia (HP:0003348) | 2.51989386 |
| 45 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.51465315 |
| 46 | Inability to walk (HP:0002540) | 2.50978681 |
| 47 | Poikiloderma (HP:0001029) | 2.47947800 |
| 48 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.45211732 |
| 49 | Horizontal nystagmus (HP:0000666) | 2.43169141 |
| 50 | Hypoplastic iliac wings (HP:0002866) | 2.40792316 |
| 51 | Medial flaring of the eyebrow (HP:0010747) | 2.39895026 |
| 52 | Tubular atrophy (HP:0000092) | 2.39328219 |
| 53 | Oligodactyly (HP:0012165) | 2.38156071 |
| 54 | Cerebellar dysplasia (HP:0007033) | 2.38095113 |
| 55 | Nephrogenic diabetes insipidus (HP:0009806) | 2.37286178 |
| 56 | Genital tract atresia (HP:0001827) | 2.35770062 |
| 57 | Macular degeneration (HP:0000608) | 2.29894374 |
| 58 | Supernumerary spleens (HP:0009799) | 2.28142414 |
| 59 | Vaginal atresia (HP:0000148) | 2.27145760 |
| 60 | Fibular hypoplasia (HP:0003038) | 2.23742891 |
| 61 | Chorioretinal atrophy (HP:0000533) | 2.23263747 |
| 62 | Postaxial foot polydactyly (HP:0001830) | 2.15786941 |
| 63 | Abnormality of DNA repair (HP:0003254) | 2.14078500 |
| 64 | Polyuria (HP:0000103) | 2.13199693 |
| 65 | Bicornuate uterus (HP:0000813) | 2.12566030 |
| 66 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.10109925 |
| 67 | Duodenal stenosis (HP:0100867) | 2.08165076 |
| 68 | Small intestinal stenosis (HP:0012848) | 2.08165076 |
| 69 | Tubulointerstitial abnormality (HP:0001969) | 2.07417102 |
| 70 | Fair hair (HP:0002286) | 2.07304723 |
| 71 | Multicystic kidney dysplasia (HP:0000003) | 2.06241555 |
| 72 | Abolished electroretinogram (ERG) (HP:0000550) | 2.06114106 |
| 73 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.03492598 |
| 74 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.03492598 |
| 75 | Abnormal protein glycosylation (HP:0012346) | 2.03492598 |
| 76 | Abnormal glycosylation (HP:0012345) | 2.03492598 |
| 77 | Decreased circulating renin level (HP:0003351) | 2.03251185 |
| 78 | Hyperventilation (HP:0002883) | 2.02873647 |
| 79 | Widely spaced teeth (HP:0000687) | 2.01141797 |
| 80 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 12.0664369 |
| 81 | Absent/shortened dynein arms (HP:0200106) | 11.4652116 |
| 82 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 11.4652116 |
| 83 | Abnormal lung lobation (HP:0002101) | 1.98482972 |
| 84 | Poor coordination (HP:0002370) | 1.97532671 |
| 85 | Type I transferrin isoform profile (HP:0003642) | 1.97381524 |
| 86 | Astigmatism (HP:0000483) | 1.97378965 |
| 87 | Degeneration of anterior horn cells (HP:0002398) | 1.97372084 |
| 88 | Abnormality of the anterior horn cell (HP:0006802) | 1.97372084 |
| 89 | Oculomotor apraxia (HP:0000657) | 1.96905932 |
| 90 | Absent speech (HP:0001344) | 1.96666871 |
| 91 | Recurrent bronchitis (HP:0002837) | 1.95578964 |
| 92 | Lissencephaly (HP:0001339) | 1.95549062 |
| 93 | Stage 5 chronic kidney disease (HP:0003774) | 1.95301967 |
| 94 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.90453697 |
| 95 | Absent epiphyses (HP:0010577) | 1.90453697 |
| 96 | Progressive cerebellar ataxia (HP:0002073) | 1.89551454 |
| 97 | 11 pairs of ribs (HP:0000878) | 1.89001204 |
| 98 | Febrile seizures (HP:0002373) | 1.88054324 |
| 99 | Short ribs (HP:0000773) | 1.87305733 |
| 100 | Retinitis pigmentosa (HP:0000510) | 1.86404591 |
| 101 | Potter facies (HP:0002009) | 1.84267954 |
| 102 | Facial shape deformation (HP:0011334) | 1.84267954 |
| 103 | Upper motor neuron abnormality (HP:0002127) | 1.83883666 |
| 104 | Facial cleft (HP:0002006) | 1.83570659 |
| 105 | Pancreatic fibrosis (HP:0100732) | 1.82548679 |
| 106 | Abnormality of the corticospinal tract (HP:0002492) | 1.80717824 |
| 107 | Congenital hepatic fibrosis (HP:0002612) | 1.79161773 |
| 108 | Ectopic kidney (HP:0000086) | 1.78993795 |
| 109 | Atonic seizures (HP:0010819) | 1.78267154 |
| 110 | Hyperkalemia (HP:0002153) | 1.77979762 |
| 111 | Abnormal urine output (HP:0012590) | 1.77920271 |
| 112 | Hypophosphatemic rickets (HP:0004912) | 1.77193844 |
| 113 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.76213649 |
| 114 | Bell-shaped thorax (HP:0001591) | 1.75912648 |
| 115 | Non-midline cleft lip (HP:0100335) | 1.75453451 |
| 116 | Selective tooth agenesis (HP:0001592) | 1.69573430 |
| 117 | Impaired proprioception (HP:0010831) | 1.67799018 |
| 118 | Postaxial hand polydactyly (HP:0001162) | 1.66463745 |
| 119 | Broad distal phalanx of finger (HP:0009836) | 1.64932893 |
| 120 | Spastic tetraparesis (HP:0001285) | 1.63131810 |
| 121 | Abnormality of the dental root (HP:0006486) | 1.60945021 |
| 122 | Taurodontia (HP:0000679) | 1.60945021 |
| 123 | Abnormality of permanent molar morphology (HP:0011071) | 1.60945021 |
| 124 | Median cleft lip (HP:0000161) | 1.60114686 |
| 125 | Renal dysplasia (HP:0000110) | 1.59524500 |
| 126 | Cholecystitis (HP:0001082) | 1.57604053 |
| 127 | Abnormal gallbladder physiology (HP:0012438) | 1.57604053 |
| 128 | True hermaphroditism (HP:0010459) | 1.56938464 |
| 129 | Abnormality of molar morphology (HP:0011070) | 1.56799108 |
| 130 | Abnormality of molar (HP:0011077) | 1.56799108 |
| 131 | Abnormality of dentin (HP:0010299) | 1.54191820 |
| 132 | Abnormal drinking behavior (HP:0030082) | 1.53099362 |
| 133 | Polydipsia (HP:0001959) | 1.53099362 |
| 134 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.52681530 |
| 135 | Heterotopia (HP:0002282) | 1.52633143 |
| 136 | Sloping forehead (HP:0000340) | 1.51399430 |
| 137 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.49292365 |
| 138 | Microglossia (HP:0000171) | 1.48496784 |
| 139 | Meckel diverticulum (HP:0002245) | 1.46524496 |
| 140 | Tubulointerstitial fibrosis (HP:0005576) | 1.44825960 |
| 141 | Cystic liver disease (HP:0006706) | 1.43707131 |
| 142 | Abnormality of the ileum (HP:0001549) | 1.43204287 |
| 143 | Absent frontal sinuses (HP:0002688) | 1.42875153 |
| 144 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.41819753 |
| 145 | Abnormality of the dental pulp (HP:0006479) | 1.41750256 |
| 146 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.40150290 |
| 147 | Congenital primary aphakia (HP:0007707) | 1.38781705 |
| 148 | Choroideremia (HP:0001139) | 1.38417465 |
| 149 | Gait imbalance (HP:0002141) | 1.37639778 |
| 150 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.33237019 |
| 151 | Short thorax (HP:0010306) | 1.32758152 |
| 152 | Abnormality of the renal cortex (HP:0011035) | 1.31794242 |
| 153 | Gaze-evoked nystagmus (HP:0000640) | 1.31212955 |
| 154 | Occipital encephalocele (HP:0002085) | 1.30565501 |
| 155 | Abnormality of the preputium (HP:0100587) | 1.29780700 |
| 156 | Bundle branch block (HP:0011710) | 1.28745207 |
| 157 | Premature ovarian failure (HP:0008209) | 1.27993451 |
| 158 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.27472209 |
| 159 | Abnormal biliary tract physiology (HP:0012439) | 1.27124797 |
| 160 | Bile duct proliferation (HP:0001408) | 1.27124797 |
| 161 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.26238148 |
| 162 | Congenital malformation of the right heart (HP:0011723) | 1.25790840 |
| 163 | Double outlet right ventricle (HP:0001719) | 1.25790840 |
| 164 | Chronic sinusitis (HP:0011109) | 1.25700711 |
| 165 | Global brain atrophy (HP:0002283) | 1.25691422 |
| 166 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.25266624 |
| 167 | Personality changes (HP:0000751) | 1.22638222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PDK4 | 8.21071640 |
| 2 | PDK3 | 8.21071640 |
| 3 | PDK2 | 5.26217012 |
| 4 | TESK1 | 4.56026237 |
| 5 | PRKD3 | 4.14813922 |
| 6 | FRK | 4.03318050 |
| 7 | ICK | 3.35196849 |
| 8 | PNCK | 2.65038130 |
| 9 | ADRBK2 | 2.56261674 |
| 10 | NEK2 | 2.53720883 |
| 11 | NEK6 | 2.49980140 |
| 12 | PTK2B | 2.22547810 |
| 13 | MAP4K2 | 2.20122469 |
| 14 | MET | 2.15200706 |
| 15 | OXSR1 | 2.15000730 |
| 16 | BMPR1B | 2.02899551 |
| 17 | INSRR | 1.82575757 |
| 18 | TTK | 1.64464794 |
| 19 | WEE1 | 1.63680733 |
| 20 | MAPK13 | 1.61993370 |
| 21 | CDC7 | 1.58324054 |
| 22 | STK38 | 1.58266304 |
| 23 | WNK4 | 1.47266775 |
| 24 | TRIM28 | 1.41597367 |
| 25 | CSF1R | 1.32859039 |
| 26 | NEK9 | 1.30966660 |
| 27 | ZAK | 1.29700488 |
| 28 | GRK1 | 1.28060452 |
| 29 | STK39 | 1.27410680 |
| 30 | CCNB1 | 1.26941239 |
| 31 | BUB1 | 1.17504166 |
| 32 | DYRK3 | 1.08735531 |
| 33 | PLK4 | 1.07954624 |
| 34 | BRAF | 1.05028601 |
| 35 | CHEK2 | 1.05024559 |
| 36 | TYRO3 | 1.03557439 |
| 37 | FGR | 1.01473217 |
| 38 | TIE1 | 0.92869064 |
| 39 | CSNK1A1L | 0.92574720 |
| 40 | TNK2 | 0.91902133 |
| 41 | MAPK15 | 0.89213246 |
| 42 | PDK1 | 0.88505670 |
| 43 | PRKCE | 0.86298607 |
| 44 | PLK1 | 0.86285879 |
| 45 | STK3 | 0.85337519 |
| 46 | VRK1 | 0.84935667 |
| 47 | MAP3K2 | 0.84510000 |
| 48 | CASK | 0.83846765 |
| 49 | PASK | 0.82721898 |
| 50 | PRKCI | 0.80932609 |
| 51 | NUAK1 | 0.80003020 |
| 52 | EEF2K | 0.75892166 |
| 53 | ADRBK1 | 0.75789127 |
| 54 | CHEK1 | 0.74793686 |
| 55 | BCR | 0.73970531 |
| 56 | TLK1 | 0.73912411 |
| 57 | ATR | 0.73689051 |
| 58 | DYRK1B | 0.72982733 |
| 59 | EIF2AK3 | 0.71194280 |
| 60 | WNK1 | 0.68737120 |
| 61 | AKT3 | 0.68722815 |
| 62 | CSNK1G2 | 0.68124157 |
| 63 | BMX | 0.67867907 |
| 64 | PINK1 | 0.65325950 |
| 65 | STK38L | 0.65232641 |
| 66 | CAMK1 | 0.60650443 |
| 67 | MAP3K4 | 0.60552127 |
| 68 | ERBB3 | 0.59315768 |
| 69 | MST1R | 0.57979589 |
| 70 | MATK | 0.57811082 |
| 71 | PIK3CG | 0.57431357 |
| 72 | MAP3K10 | 0.57416823 |
| 73 | TAOK1 | 0.55986051 |
| 74 | EGFR | 0.55528530 |
| 75 | PKN1 | 0.54037197 |
| 76 | EIF2AK1 | 0.53776220 |
| 77 | MAPKAPK3 | 0.53347623 |
| 78 | ATM | 0.51931047 |
| 79 | RPS6KA4 | 0.51749632 |
| 80 | CAMK2A | 0.50505012 |
| 81 | EPHA4 | 0.50464098 |
| 82 | DDR2 | 0.50303828 |
| 83 | CSNK1G3 | 0.49232073 |
| 84 | KIT | 0.48903880 |
| 85 | RIPK4 | 0.48625593 |
| 86 | MAP2K2 | 0.47794828 |
| 87 | WNK3 | 0.46987693 |
| 88 | CDK12 | 0.46646503 |
| 89 | SRPK1 | 0.44018770 |
| 90 | BRSK2 | 0.43686187 |
| 91 | MAP3K9 | 0.42299640 |
| 92 | TXK | 0.41838055 |
| 93 | AURKA | 0.41605141 |
| 94 | PAK1 | 0.41512724 |
| 95 | PRKCG | 0.40345177 |
| 96 | PLK3 | 0.40015169 |
| 97 | PRKG1 | 0.39609161 |
| 98 | TESK2 | 0.37928426 |
| 99 | IGF1R | 0.37741349 |
| 100 | CSNK1G1 | 0.37337914 |
| 101 | PAK6 | 0.36265933 |
| 102 | NTRK2 | 0.36026376 |
| 103 | BCKDK | 0.35748843 |
| 104 | PDPK1 | 0.34879821 |
| 105 | PRKCZ | 0.34829154 |
| 106 | DAPK1 | 0.34578673 |
| 107 | CDK4 | 0.34564867 |
| 108 | BRSK1 | 0.34425503 |
| 109 | MAP2K6 | 0.34164090 |
| 110 | IRAK1 | 0.32739043 |
| 111 | MTOR | 0.32380062 |
| 112 | CDK3 | 0.32121639 |
| 113 | MAP2K7 | 0.31668527 |
| 114 | TAOK3 | 0.31592870 |
| 115 | MAP2K4 | 0.31280481 |
| 116 | MARK3 | 0.30913534 |
| 117 | RPS6KA5 | 0.30422888 |
| 118 | CAMK1G | 0.29757451 |
| 119 | CDK2 | 0.28786218 |
| 120 | CDK7 | 0.28219946 |
| 121 | PAK4 | 0.27962179 |
| 122 | PRKCQ | 0.27332780 |
| 123 | MKNK2 | 0.27220417 |
| 124 | LATS2 | 0.26976744 |
| 125 | MUSK | 0.26442369 |
| 126 | MINK1 | 0.26409472 |
| 127 | AURKB | 0.26004155 |
| 128 | PLK2 | 0.24771660 |
| 129 | MKNK1 | 0.24128060 |
| 130 | CDK1 | 0.23349594 |
| 131 | BRD4 | 0.22363512 |
| 132 | CAMKK1 | 0.22251884 |
| 133 | STK16 | 0.21647427 |
| 134 | PRKAA1 | 0.20365603 |
| 135 | CDK11A | 0.15454061 |
| 136 | GSK3B | 0.15359400 |
| 137 | CDK18 | 0.15209884 |
| 138 | NTRK3 | 0.15005403 |
| 139 | CDK15 | 0.14984343 |
| 140 | CSNK2A1 | 0.14174101 |
| 141 | PAK2 | 0.12800367 |
| 142 | MAPKAPK5 | 0.12122432 |
| 143 | CSNK1E | 0.11896106 |
| 144 | DAPK2 | 0.11867588 |
| 145 | STK10 | 0.11417476 |
| 146 | MAP3K8 | 0.11201598 |
| 147 | CSNK2A2 | 0.10935988 |
| 148 | PRKDC | 0.10931209 |
| 149 | RPS6KB1 | 0.10535338 |
| 150 | STK11 | 0.09766110 |
| 151 | CDK19 | 0.09367564 |
| 152 | ARAF | 0.09270966 |
| 153 | RPS6KA1 | 0.08591083 |
| 154 | MARK1 | 0.08267161 |
| 155 | ACVR1B | 0.07014289 |
| 156 | MAPK10 | 0.06755024 |
| 157 | NEK1 | 0.06525142 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 4.65595287 |
| 2 | Basal transcription factors_Homo sapiens_hsa03022 | 3.43186948 |
| 3 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.13656975 |
| 4 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 3.10875179 |
| 5 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.75241119 |
| 6 | Oocyte meiosis_Homo sapiens_hsa04114 | 2.68719831 |
| 7 | RNA transport_Homo sapiens_hsa03013 | 2.60868206 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.58882070 |
| 9 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.50569417 |
| 10 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.35354243 |
| 11 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 2.19989664 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.11038051 |
| 13 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.10516550 |
| 14 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.08264476 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.05227824 |
| 16 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.05201037 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 2.01845002 |
| 18 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.01550540 |
| 19 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.01543222 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.87916292 |
| 21 | Morphine addiction_Homo sapiens_hsa05032 | 1.84012709 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.77192000 |
| 23 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.72411671 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.71486534 |
| 25 | Cell cycle_Homo sapiens_hsa04110 | 1.69952376 |
| 26 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.60915604 |
| 27 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.60532162 |
| 28 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.59651657 |
| 29 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.59171912 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.55908707 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.55020611 |
| 32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.52033222 |
| 33 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.51986672 |
| 34 | ABC transporters_Homo sapiens_hsa02010 | 1.50788465 |
| 35 | Long-term potentiation_Homo sapiens_hsa04720 | 1.49023691 |
| 36 | Mismatch repair_Homo sapiens_hsa03430 | 1.47587376 |
| 37 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.47090932 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.45830655 |
| 39 | GABAergic synapse_Homo sapiens_hsa04727 | 1.43048206 |
| 40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.39510161 |
| 41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.38508250 |
| 42 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.36088335 |
| 43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.33875914 |
| 44 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.33671284 |
| 45 | Sulfur relay system_Homo sapiens_hsa04122 | 1.32747098 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31217338 |
| 47 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.30449163 |
| 48 | RNA degradation_Homo sapiens_hsa03018 | 1.27947195 |
| 49 | Spliceosome_Homo sapiens_hsa03040 | 1.27930919 |
| 50 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.24520522 |
| 51 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.20851729 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 1.19064237 |
| 53 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.16762792 |
| 54 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.16070559 |
| 55 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.15510182 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.14926169 |
| 57 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.14485695 |
| 58 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.13502718 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.13314419 |
| 60 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.11586587 |
| 61 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.09994244 |
| 62 | Renin secretion_Homo sapiens_hsa04924 | 1.09490561 |
| 63 | Allograft rejection_Homo sapiens_hsa05330 | 1.08247898 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.07651972 |
| 65 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.07486102 |
| 66 | Lysine degradation_Homo sapiens_hsa00310 | 1.06714304 |
| 67 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.05772967 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 1.01705559 |
| 69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.01249063 |
| 70 | Proteasome_Homo sapiens_hsa03050 | 1.01045103 |
| 71 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.98864038 |
| 72 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.98056455 |
| 73 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.97055368 |
| 74 | Nicotine addiction_Homo sapiens_hsa05033 | 0.95872169 |
| 75 | Circadian rhythm_Homo sapiens_hsa04710 | 0.95118531 |
| 76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94966986 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.94412250 |
| 78 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.92777016 |
| 79 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.92211572 |
| 80 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.91071704 |
| 81 | RNA polymerase_Homo sapiens_hsa03020 | 0.88794728 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87722251 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.87006564 |
| 84 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.86930572 |
| 85 | Carbon metabolism_Homo sapiens_hsa01200 | 0.86360178 |
| 86 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.85375715 |
| 87 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.85341156 |
| 88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.85117414 |
| 89 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.82395203 |
| 90 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.75575264 |
| 91 | Histidine metabolism_Homo sapiens_hsa00340 | 0.73256778 |
| 92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72977469 |
| 93 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.69217452 |
| 94 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.68746961 |
| 95 | Peroxisome_Homo sapiens_hsa04146 | 0.68530691 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.68054057 |
| 97 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.66045285 |
| 98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.65189145 |
| 99 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.64669155 |
| 100 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.64192316 |
| 101 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.64087255 |
| 102 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.61395312 |
| 103 | Protein export_Homo sapiens_hsa03060 | 0.60872879 |
| 104 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.59143328 |
| 105 | Taste transduction_Homo sapiens_hsa04742 | 0.58936268 |
| 106 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58643820 |
| 107 | Circadian entrainment_Homo sapiens_hsa04713 | 0.58349052 |
| 108 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.58332453 |
| 109 | Insulin secretion_Homo sapiens_hsa04911 | 0.56206585 |
| 110 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.55023212 |
| 111 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.54893542 |
| 112 | Salivary secretion_Homo sapiens_hsa04970 | 0.53517859 |
| 113 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51952664 |
| 114 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51549368 |
| 115 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.50696016 |
| 116 | Phototransduction_Homo sapiens_hsa04744 | 0.49684298 |
| 117 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48576895 |
| 118 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47333454 |
| 119 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.46497414 |
| 120 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.46332514 |
| 121 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.46214486 |
| 122 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.45834081 |
| 123 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45799844 |
| 124 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42962649 |
| 125 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.42889666 |
| 126 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42695294 |
| 127 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.42225839 |
| 128 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.41294294 |
| 129 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40535972 |
| 130 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.39617372 |
| 131 | Alcoholism_Homo sapiens_hsa05034 | 0.39178041 |
| 132 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.38286287 |
| 133 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.37723909 |
| 134 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37681166 |
| 135 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.36449060 |
| 136 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.35802519 |
| 137 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.35390924 |
| 138 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.35318619 |
| 139 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.32860356 |
| 140 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.32800573 |
| 141 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.32770487 |
| 142 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.31816474 |
| 143 | Metabolic pathways_Homo sapiens_hsa01100 | 0.31345437 |
| 144 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.31084317 |
| 145 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.30826749 |
| 146 | Long-term depression_Homo sapiens_hsa04730 | 0.29703145 |
| 147 | HTLV-I infection_Homo sapiens_hsa05166 | 0.29431866 |
| 148 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.28884597 |
| 149 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.28224404 |
| 150 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.26363112 |
| 151 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.26120921 |
| 152 | Endocytosis_Homo sapiens_hsa04144 | 0.25549800 |
| 153 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.25547397 |
| 154 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.25512769 |
| 155 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.23641507 |
| 156 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23247448 |

