CCDC17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1left/right pattern formation (GO:0060972)9.15836296
2regulation of cilium movement (GO:0003352)7.96163321
3glycoside metabolic process (GO:0016137)7.26984494
4vitamin transmembrane transport (GO:0035461)6.98051712
5left/right axis specification (GO:0070986)6.92526960
6ventricular system development (GO:0021591)6.65479983
7microtubule bundle formation (GO:0001578)6.36213916
8diterpenoid biosynthetic process (GO:0016102)6.14636311
9tolerance induction (GO:0002507)5.73176945
10cilium organization (GO:0044782)5.68067002
11signal peptide processing (GO:0006465)5.54104394
12response to xenobiotic stimulus (GO:0009410)5.50506667
13cilium assembly (GO:0042384)5.50493075
14pyrimidine-containing compound transmembrane transport (GO:0072531)5.48205792
15one-carbon compound transport (GO:0019755)5.09897609
16lung epithelium development (GO:0060428)5.07010068
17centriole assembly (GO:0098534)5.06507862
18negative regulation of immunoglobulin mediated immune response (GO:0002890)4.94767088
19negative regulation of B cell mediated immunity (GO:0002713)4.94767088
20ethanol oxidation (GO:0006069)4.77605245
21establishment of apical/basal cell polarity (GO:0035089)4.73842639
22negative regulation of T cell differentiation in thymus (GO:0033085)4.71199616
23protein localization to cilium (GO:0061512)4.71129639
24cytidine deamination (GO:0009972)4.68560537
25cytidine metabolic process (GO:0046087)4.68560537
26cytidine catabolic process (GO:0006216)4.68560537
27regulation of interleukin-5 production (GO:0032674)4.64663611
28regulation of germinal center formation (GO:0002634)4.60750129
29regulation of microtubule-based movement (GO:0060632)4.60397663
30positive regulation of tolerance induction (GO:0002645)4.58655233
31sperm capacitation (GO:0048240)4.55728091
32glomerular epithelial cell development (GO:0072310)4.54065339
33antigen processing and presentation of endogenous antigen (GO:0019883)4.51071339
34microtubule-based movement (GO:0007018)4.50606493
35cellular component assembly involved in morphogenesis (GO:0010927)4.34785452
36natural killer cell activation involved in immune response (GO:0002323)4.24621413
37terpenoid biosynthetic process (GO:0016114)4.21053184
38retinoic acid metabolic process (GO:0042573)4.11262480
39pyrimidine ribonucleoside catabolic process (GO:0046133)4.09985041
40cell projection assembly (GO:0030031)4.05407197
41antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.04213164
42antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.04213164
43establishment of monopolar cell polarity (GO:0061162)4.04195419
44establishment or maintenance of monopolar cell polarity (GO:0061339)4.04195419
45cilium morphogenesis (GO:0060271)3.92616449
46cytoplasmic microtubule organization (GO:0031122)3.80736935
47negative regulation of inclusion body assembly (GO:0090084)3.66687440
48nucleoside diphosphate phosphorylation (GO:0006165)3.65999835
49exogenous drug catabolic process (GO:0042738)3.61453629
50regulation of tolerance induction (GO:0002643)3.60682383
51microtubule depolymerization (GO:0007019)3.53365169
52ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)3.48792227
53lateral ventricle development (GO:0021670)3.40268196
54hydrogen peroxide biosynthetic process (GO:0050665)3.40267821
55antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.39449956
56cilium movement (GO:0003341)3.37115935
57microtubule polymerization or depolymerization (GO:0031109)3.35822926
58primary alcohol metabolic process (GO:0034308)3.34930335
59O-glycan processing (GO:0016266)3.28858435
60NIK/NF-kappaB signaling (GO:0038061)3.28619413
61axoneme assembly (GO:0035082)3.27617628
62negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.27029818
63primary alcohol catabolic process (GO:0034310)3.25227921
64complement activation, classical pathway (GO:0006958)3.22215893
65retinol metabolic process (GO:0042572)3.21537402
66establishment of tissue polarity (GO:0007164)3.18238674
67establishment of planar polarity (GO:0001736)3.18238674
68axonemal dynein complex assembly (GO:0070286)3.14847015
69nucleoside diphosphate catabolic process (GO:0009134)3.10950490
70cellular response to interferon-beta (GO:0035458)3.05160088
71reactive oxygen species biosynthetic process (GO:1903409)3.03670554
72positive regulation of smoothened signaling pathway (GO:0045880)3.02803623
73regulation of microtubule depolymerization (GO:0031114)3.02034216
74glutathione derivative biosynthetic process (GO:1901687)2.99841171
75glutathione derivative metabolic process (GO:1901685)2.99841171
76sequestering of metal ion (GO:0051238)2.96772772
77hypotonic response (GO:0006971)2.96760912
78multicellular organismal water homeostasis (GO:0050891)2.94521903
79phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.92232500
80response to interferon-beta (GO:0035456)2.91963097
81cellular response to antibiotic (GO:0071236)2.91389837
82maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.91156176
83exocrine pancreas development (GO:0031017)2.84707763
84progesterone metabolic process (GO:0042448)2.83014238
85regulation of response to osmotic stress (GO:0047484)2.82953449
86regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.80716824
87COPI coating of Golgi vesicle (GO:0048205)2.80086027
88Golgi transport vesicle coating (GO:0048200)2.80086027
89drug catabolic process (GO:0042737)2.79624249
90carnitine metabolic process (GO:0009437)2.79270375
91ethanol metabolic process (GO:0006067)2.77981791
92iron ion import (GO:0097286)2.72565894
93muscle organ morphogenesis (GO:0048644)2.71258523
94melanosome transport (GO:0032402)2.69825619
95phosphatidylcholine biosynthetic process (GO:0006656)2.67310377
96response to type I interferon (GO:0034340)2.66550944
97multicellular organismal aging (GO:0010259)2.65687208
98microtubule-based process (GO:0007017)2.64703659
99melanocyte differentiation (GO:0030318)2.64343636
100complement activation (GO:0006956)2.64307156
101cellular response to type I interferon (GO:0071357)2.63908043
102type I interferon signaling pathway (GO:0060337)2.63908043
103hydrogen peroxide catabolic process (GO:0042744)2.63593874
104positive regulation of B cell differentiation (GO:0045579)2.61831410
105regulation of apoptotic cell clearance (GO:2000425)2.61466930
106sperm motility (GO:0030317)2.60816530
107determination of left/right symmetry (GO:0007368)2.59884723
108pyrimidine nucleoside catabolic process (GO:0046135)2.59297250
109nucleotide transmembrane transport (GO:1901679)2.58902074
110regulation of B cell receptor signaling pathway (GO:0050855)2.58804100
111excretion (GO:0007588)2.58099596
112protein retention in ER lumen (GO:0006621)2.57603979
113establishment of melanosome localization (GO:0032401)2.56571909
114calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.55802881
115regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.55261154
116regulation of autophagic vacuole assembly (GO:2000785)2.54844889
117dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.54303325
118lateral sprouting from an epithelium (GO:0060601)2.53054840
119ER overload response (GO:0006983)2.52250126
120retinal rod cell development (GO:0046548)2.52025808
121L-phenylalanine catabolic process (GO:0006559)2.51827166
122erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.51827166
123pigment granule transport (GO:0051904)2.51494128
124apical protein localization (GO:0045176)2.51146869
125UDP-N-acetylglucosamine metabolic process (GO:0006047)2.51141870
126regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.51086683
127water homeostasis (GO:0030104)2.50744232
128polyol transport (GO:0015791)2.50427273
129determination of bilateral symmetry (GO:0009855)2.49499355
130pigment cell differentiation (GO:0050931)2.47861022
131N-acetylneuraminate metabolic process (GO:0006054)2.47638578
132regulation of interleukin-6 biosynthetic process (GO:0045408)2.47272164
133regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.47168416
134negative regulation of stress fiber assembly (GO:0051497)2.45823932
135negative regulation of adaptive immune response (GO:0002820)2.45646712
136oligosaccharide biosynthetic process (GO:0009312)2.45619805
137surfactant homeostasis (GO:0043129)2.45483045
138negative regulation of glucose import (GO:0046325)2.45295993
139organelle assembly (GO:0070925)2.44509657
140negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.44211070
141regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.42184883
142glucosamine-containing compound catabolic process (GO:1901072)2.42058210
143negative regulation of humoral immune response (GO:0002921)2.41694028
144glycolipid catabolic process (GO:0019377)2.41597221
145negative regulation of glucose transport (GO:0010829)2.41380164
146glycosphingolipid catabolic process (GO:0046479)2.40071260
147establishment of pigment granule localization (GO:0051905)2.39676109
148melanosome localization (GO:0032400)2.39178547
149regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.38433461
150endocrine pancreas development (GO:0031018)2.38371353
151ribosomal small subunit assembly (GO:0000028)2.36182745
152positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.36152885
153autophagic vacuole fusion (GO:0000046)2.35775363
154leukocyte degranulation (GO:0043299)2.35329199
155phospholipid scrambling (GO:0017121)2.33980076
156regulation of B cell differentiation (GO:0045577)2.33329205
157presynaptic membrane assembly (GO:0097105)2.33132525
158L-phenylalanine metabolic process (GO:0006558)2.32833136
159erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.32833136
160negative regulation of glycoprotein biosynthetic process (GO:0010561)2.32020502
161aldehyde catabolic process (GO:0046185)2.31502488
162serine transport (GO:0032329)2.29754313
163intraciliary transport (GO:0042073)2.29483453
164fatty acid elongation (GO:0030497)2.29069078
165negative regulation of transcription by competitive promoter binding (GO:0010944)2.27091798
166GTP biosynthetic process (GO:0006183)2.26993801
167purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.26047281
1683-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.26047281
169ceramide catabolic process (GO:0046514)2.25073509
170cellular response to exogenous dsRNA (GO:0071360)2.25056219
171nucleotide transport (GO:0006862)2.24809587
172pigment granule localization (GO:0051875)2.24415454
173nucleotide-sugar metabolic process (GO:0009225)2.24188161
174regulation of glucose import in response to insulin stimulus (GO:2001273)2.23666038
175aromatic amino acid family catabolic process (GO:0009074)2.22317113
176regulation of interleukin-13 production (GO:0032656)2.22237222
177neuroepithelial cell differentiation (GO:0060563)2.21279295
178intracellular pH reduction (GO:0051452)2.21192262
179SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.21180569
180protein activation cascade (GO:0072376)2.20656559
181organelle membrane fusion (GO:0090174)2.20481736
182cotranslational protein targeting to membrane (GO:0006613)2.20084885
183positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.19285624
184toxin metabolic process (GO:0009404)2.17792940
185mature B cell differentiation involved in immune response (GO:0002313)2.17510376
186cilium or flagellum-dependent cell motility (GO:0001539)18.5115801
187motile cilium assembly (GO:0044458)15.1383709
188epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)14.3845761
189epithelial cilium movement (GO:0003351)13.2811961

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.59996578
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.71151103
3IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.76932433
4NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.68174542
5DROSHA_22980978_ChIP-Seq_HELA_Human3.36464862
6GATA1_22025678_ChIP-Seq_K562_Human2.78228544
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.77866247
8CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.70952841
9FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.63224354
10ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.57751203
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.53828382
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.50515085
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.41514140
14CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.35338704
15TRIM28_21343339_ChIP-Seq_HEK293_Human2.35309706
16PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.29401742
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.19554098
18RXR_22158963_ChIP-Seq_LIVER_Mouse2.16442019
19SMC4_20622854_ChIP-Seq_HELA_Human2.13060993
20PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.11269619
21RUNX1_27514584_Chip-Seq_MCF-7_Human2.10850948
22RUNX_20019798_ChIP-Seq_JUKART_Human2.03960063
23SOX2_27498859_Chip-Seq_STOMACH_Mouse2.03322941
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.98668023
25SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.98373953
26LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.92529842
27TP63_17297297_ChIP-ChIP_HaCaT_Human1.91984073
28MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.86546168
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.84778925
30IRF8_27001747_Chip-Seq_BMDM_Mouse1.82094318
31RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.82078146
32STAT1_20625510_ChIP-Seq_HELA_Human1.81901901
33PPARA_22158963_ChIP-Seq_LIVER_Mouse1.80777432
34FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.79804328
35EGR1_23403033_ChIP-Seq_LIVER_Mouse1.78074155
36CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.76530528
37ESR1_21235772_ChIP-Seq_MCF-7_Human1.73382972
38LXR_22158963_ChIP-Seq_LIVER_Mouse1.73358312
39AHR_22903824_ChIP-Seq_MCF-7_Human1.72145968
40STAT4_19710469_ChIP-ChIP_TH1__Mouse1.70717672
41ELF1_20517297_ChIP-Seq_JURKAT_Human1.70283346
42KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.70139962
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.64456933
44* TP63_22573176_ChIP-Seq_HFKS_Human1.63869366
45SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.63799271
46SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.61256959
47PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.59504339
48ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.59393111
49FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.59298945
50P68_20966046_ChIP-Seq_HELA_Human1.57886871
51RACK7_27058665_Chip-Seq_MCF-7_Human1.57386082
52KLF5_25053715_ChIP-Seq_YYC3_Human1.57188908
53NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.53078671
54IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.51667497
55SCL_19346495_ChIP-Seq_HPC-7_Human1.50839935
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.48125521
57LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.47215486
58STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.45980810
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.44758709
60BP1_19119308_ChIP-ChIP_Hs578T_Human1.44323503
61TDRD3_21172665_ChIP-Seq_MCF-7_Human1.44214901
62ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.43871958
63* TP63_23658742_ChIP-Seq_EP156T_Human1.43801038
64SRF_21415370_ChIP-Seq_HL-1_Mouse1.42857033
65RAD21_21589869_ChIP-Seq_MESCs_Mouse1.42706357
66FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.40847143
67TAF15_26573619_Chip-Seq_HEK293_Human1.40200809
68IKZF1_21737484_ChIP-ChIP_HCT116_Human1.39870597
69CREB1_26743006_Chip-Seq_LNCaP_Human1.37351825
70ARNT_22903824_ChIP-Seq_MCF-7_Human1.37201800
71FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.35885606
72NOTCH1_21737748_ChIP-Seq_TLL_Human1.34959156
73PHF8_20622854_ChIP-Seq_HELA_Human1.34573809
74GATA3_27048872_Chip-Seq_THYMUS_Human1.33150842
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.33058515
76* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.32645793
77FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.32475584
78YY1_22570637_ChIP-Seq_MALME-3M_Human1.32173784
79MYB_26560356_Chip-Seq_TH2_Human1.31460506
80SOX2_20726797_ChIP-Seq_SW620_Human1.31286193
81ELF1_17652178_ChIP-ChIP_JURKAT_Human1.30083949
82KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.28708815
83FOXM1_26456572_ChIP-Seq_MCF-7_Human1.28687525
84CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.28360174
85FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.28265327
86GATA2_21666600_ChIP-Seq_HMVEC_Human1.28141232
87CTCF_20526341_ChIP-Seq_ESCs_Human1.26399581
88FOXA1_25552417_ChIP-Seq_VCAP_Human1.26074572
89* CTCF_27219007_Chip-Seq_Bcells_Human1.23219646
90Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.21829920
91HOXB4_20404135_ChIP-ChIP_EML_Mouse1.20406484
92FOXO3_23340844_ChIP-Seq_DLD1_Human1.19887580
93GATA2_19941826_ChIP-Seq_K562_Human1.18016865
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17760934
95PIAS1_25552417_ChIP-Seq_VCAP_Human1.17197436
96GATA1_22383799_ChIP-Seq_G1ME_Mouse1.16981600
97CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.15727673
98ERG_20517297_ChIP-Seq_VCAP_Human1.15125201
99ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14827283
100* SMRT_27268052_Chip-Seq_Bcells_Human1.14471778
101BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.14430714
102TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13731043
103BCOR_27268052_Chip-Seq_Bcells_Human1.13676241
104E2F1_20622854_ChIP-Seq_HELA_Human1.13028521
105* ETV1_20927104_ChIP-Seq_GIST48_Human1.10702926
106GATA4_25053715_ChIP-Seq_YYC3_Human1.10346002
107ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.10204242
108SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.07817038
109GATA3_24758297_ChIP-Seq_MCF-7_Human1.07677534
110FOXA2_19822575_ChIP-Seq_HepG2_Human1.07345705
111GATA3_26560356_Chip-Seq_TH2_Human1.06236313
112PPAR_26484153_Chip-Seq_NCI-H1993_Human1.06076176
113GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.06046822
114ESR1_20079471_ChIP-ChIP_T-47D_Human1.05105486
115PU.1_20513432_ChIP-Seq_Bcells_Mouse1.03230578
116NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03143226
117RUNX1_22412390_ChIP-Seq_EML_Mouse1.02993933
118RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.02448078
119P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01273309
120BCL6_27268052_Chip-Seq_Bcells_Human1.00768263
121* HNFA_21074721_ChIP-Seq_CACO-2_Human1.00278851
122VDR_24763502_ChIP-Seq_THP-1_Human1.00257879
123* PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.00228690
124SPI1_23547873_ChIP-Seq_NB4_Human0.99987591
125* CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.99701138
126TP53_18474530_ChIP-ChIP_U2OS_Human0.99236926
127DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99090894
128FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.98890056
129* SA1_27219007_Chip-Seq_ERYTHROID_Human0.98364756
130FLI1_21867929_ChIP-Seq_CD8_Mouse0.98037093
131SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98026545
132NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97314752
133CDX2_20551321_ChIP-Seq_CACO-2_Human0.96996774
134ZNF263_19887448_ChIP-Seq_K562_Human0.96937461
135CEBPB_22108803_ChIP-Seq_LS180_Human0.96767333
136* PHF8_20622853_ChIP-Seq_HELA_Human0.96700552
137HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95167435
138GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94455484
139RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.94412597
140VDR_22108803_ChIP-Seq_LS180_Human0.94247959
141PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.93986304
142VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.93714112
143SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92899118
144SOX2_21211035_ChIP-Seq_LN229_Human0.92573811
145MYB_26560356_Chip-Seq_TH1_Human0.91292364
146GATA1_19941826_ChIP-Seq_K562_Human0.90923951
147TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89802778
148* RBPJ_21746931_ChIP-Seq_IB4_Human0.89661188
149VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.89070506
150KDM2B_26808549_Chip-Seq_SUP-B15_Human0.88770371
151CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88563523
152SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.87932692
153P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.87850580
154PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.87314520
155TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.86883546
156* GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.86598395
157BRD4_27068464_Chip-Seq_AML-cells_Mouse0.85669519
158P300_27268052_Chip-Seq_Bcells_Human0.85542728
159HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.82037924
160TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.80505878
161TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.80390961
162* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.80302582
163THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.80146121
164GATA1_19941827_ChIP-Seq_MEL_Mouse0.78177000
165MYB_21317192_ChIP-Seq_ERMYB_Mouse0.77672158
166PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.77579201
167* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.77123889
168* MAF_26560356_Chip-Seq_TH1_Human0.76952663
169LXR_22292898_ChIP-Seq_THP-1_Human0.76379101
170SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.76217726
171PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.75369539
172POU3F2_20337985_ChIP-ChIP_501MEL_Human0.73828312
173CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.72657209
174TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.72447153
175GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.72436640
176ESR2_21235772_ChIP-Seq_MCF-7_Human0.72238980

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002653_abnormal_ependyma_morphology6.31199623
2MP0002877_abnormal_melanocyte_morpholog4.59984335
3MP0001984_abnormal_olfaction3.58694478
4MP0005623_abnormal_meninges_morphology3.27442075
5MP0003183_abnormal_peptide_metabolism3.19471756
6MP0004133_heterotaxia3.17271221
7MP0009780_abnormal_chondrocyte_physiolo3.16139925
8MP0001835_abnormal_antigen_presentation3.11209189
9MP0008789_abnormal_olfactory_epithelium2.96839050
10MP0005365_abnormal_bile_salt2.56238271
11MP0001879_abnormal_lymphatic_vessel2.45235996
12MP0005084_abnormal_gallbladder_morpholo2.44531517
13MP0003136_yellow_coat_color2.43929620
14MP0005408_hypopigmentation2.32026110
15MP0008875_abnormal_xenobiotic_pharmacok2.28621791
16MP0001790_abnormal_immune_system2.22845140
17MP0005387_immune_system_phenotype2.22845140
18MP0003878_abnormal_ear_physiology2.16144573
19MP0005377_hearing/vestibular/ear_phenot2.16144573
20MP0000383_abnormal_hair_follicle2.11418045
21MP0004019_abnormal_vitamin_homeostasis2.09817430
22MP0002168_other_aberrant_phenotype2.06123888
23MP0002132_abnormal_respiratory_system1.98185483
24MP0002933_joint_inflammation1.95227643
25MP0001800_abnormal_humoral_immune1.94963135
26MP0005671_abnormal_response_to1.94034587
27MP0010678_abnormal_skin_adnexa1.93174517
28MP0005499_abnormal_olfactory_system1.87968987
29MP0005394_taste/olfaction_phenotype1.87968987
30MP0002693_abnormal_pancreas_physiology1.87110992
31MP0002095_abnormal_skin_pigmentation1.86987693
32MP0003724_increased_susceptibility_to1.84842296
33MP0003303_peritoneal_inflammation1.84716571
34MP0002282_abnormal_trachea_morphology1.81448473
35MP0005085_abnormal_gallbladder_physiolo1.81307041
36MP0000678_abnormal_parathyroid_gland1.74263818
37MP0002909_abnormal_adrenal_gland1.74003052
38MP0001944_abnormal_pancreas_morphology1.72606554
39MP0000685_abnormal_immune_system1.64595888
40MP0002160_abnormal_reproductive_system1.64009866
41MP0010329_abnormal_lipoprotein_level1.61829110
42MP0002148_abnormal_hypersensitivity_rea1.61633476
43MP0003436_decreased_susceptibility_to1.60925101
44MP0005025_abnormal_response_to1.60700345
45MP0005000_abnormal_immune_tolerance1.60100798
46MP0009785_altered_susceptibility_to1.59664887
47MP0005310_abnormal_salivary_gland1.59441398
48MP0002452_abnormal_antigen_presenting1.57949001
49MP0005083_abnormal_biliary_tract1.56412205
50MP0002928_abnormal_bile_duct1.53807720
51MP0004264_abnormal_extraembryonic_tissu1.53777715
52MP0005464_abnormal_platelet_physiology1.53580533
53MP0002254_reproductive_system_inflammat1.53552005
54MP0001666_abnormal_nutrient_absorption1.53274842
55MP0005174_abnormal_tail_pigmentation1.53233574
56MP0002723_abnormal_immune_serum1.53059653
57MP0003868_abnormal_feces_composition1.51187231
58MP0000372_irregular_coat_pigmentation1.49361795
59MP0004782_abnormal_surfactant_physiolog1.48303731
60MP0002419_abnormal_innate_immunity1.47404680
61MP0003656_abnormal_erythrocyte_physiolo1.46357137
62MP0001919_abnormal_reproductive_system1.45592990
63MP0001346_abnormal_lacrimal_gland1.43462767
64MP0002420_abnormal_adaptive_immunity1.40792892
65MP0005220_abnormal_exocrine_pancreas1.39970619
66MP0002138_abnormal_hepatobiliary_system1.38729671
67MP0001819_abnormal_immune_cell1.36918420
68MP0002139_abnormal_hepatobiliary_system1.34574827
69MP0001270_distended_abdomen1.34481661
70MP0005165_increased_susceptibility_to1.33539793
71MP0001873_stomach_inflammation1.31266812
72MP0004043_abnormal_pH_regulation1.29108851
73MP0003879_abnormal_hair_cell1.29096525
74MP0010368_abnormal_lymphatic_system1.26122517
75MP0010234_abnormal_vibrissa_follicle1.25302195
76MP0005395_other_phenotype1.24941349
77MP0005379_endocrine/exocrine_gland_phen1.20456099
78MP0005248_abnormal_Harderian_gland1.19769286
79MP0002876_abnormal_thyroid_physiology1.18464017
80MP0003453_abnormal_keratinocyte_physiol1.14720195
81MP0009643_abnormal_urine_homeostasis1.14183819
82MP0002249_abnormal_larynx_morphology1.12843007
83MP0005584_abnormal_enzyme/coenzyme_acti1.09764698
84MP0005164_abnormal_response_to1.07211597
85MP0001845_abnormal_inflammatory_respons1.07044601
86MP0002166_altered_tumor_susceptibility1.06519624
87MP0004381_abnormal_hair_follicle1.06435071
88MP0001986_abnormal_taste_sensitivity1.06183764
89MP0009764_decreased_sensitivity_to1.05277637
90MP0006082_CNS_inflammation1.04701082
91MP0005409_darkened_coat_color1.03667736
92MP0005389_reproductive_system_phenotype1.03539863
93MP0001533_abnormal_skeleton_physiology1.02848827
94MP0000716_abnormal_immune_system1.02733220
95MP0003075_altered_response_to1.01898925
96MP0000681_abnormal_thyroid_gland1.01231153
97MP0002405_respiratory_system_inflammati1.00723863
98MP0003191_abnormal_cellular_cholesterol0.99264363
99MP0008469_abnormal_protein_level0.98982601
100MP0005360_urolithiasis0.98708457
101MP0000015_abnormal_ear_pigmentation0.98235464
102MP0002277_abnormal_respiratory_mucosa0.97543967
103MP0001849_ear_inflammation0.96925350
104MP0002118_abnormal_lipid_homeostasis0.96175198
105MP0004883_abnormal_blood_vessel0.95062432
106MP0003186_abnormal_redox_activity0.93838339
107MP0000566_synostosis0.92788224
108MP0002078_abnormal_glucose_homeostasis0.92630532
109MP0000465_gastrointestinal_hemorrhage0.92537950
110MP0009379_abnormal_foot_pigmentation0.92513711
111MP0000858_altered_metastatic_potential0.92164960
112MP0002098_abnormal_vibrissa_morphology0.92095949
113MP0002398_abnormal_bone_marrow0.91826333
114MP0010155_abnormal_intestine_physiology0.91159754
115MP0000609_abnormal_liver_physiology0.89722139
116MP0003787_abnormal_imprinting0.87966786
117MP0004947_skin_inflammation0.86999699
118MP0001851_eye_inflammation0.86949036
119MP0005058_abnormal_lysosome_morphology0.86501191
120MP0002429_abnormal_blood_cell0.82091074
121MP0001853_heart_inflammation0.80097799
122MP0005636_abnormal_mineral_homeostasis0.79885790
123MP0003195_calcinosis0.79741591
124MP0000579_abnormal_nail_morphology0.78992317
125MP0002638_abnormal_pupillary_reflex0.78944659
126MP0000013_abnormal_adipose_tissue0.78719608
127MP0001765_abnormal_ion_homeostasis0.78084912
128MP0010386_abnormal_urinary_bladder0.75943796
129MP0009765_abnormal_xenobiotic_induced0.75860730
130MP0001764_abnormal_homeostasis0.74594847
131MP0002735_abnormal_chemical_nociception0.73898210
132MP0002136_abnormal_kidney_physiology0.73485061
133MP0009763_increased_sensitivity_to0.73040297
134MP0002734_abnormal_mechanical_nocicepti0.72486776
135MP0003866_abnormal_defecation0.71218049
136MP0002233_abnormal_nose_morphology0.68660303
137MP0010030_abnormal_orbit_morphology0.66626448
138MP0001663_abnormal_digestive_system0.62642413
139MP0001929_abnormal_gametogenesis0.61514443
140MP0005388_respiratory_system_phenotype0.56552629
141MP0002133_abnormal_respiratory_system0.56552629
142MP0005023_abnormal_wound_healing0.55736099
143MP0005166_decreased_susceptibility_to0.55443175
144MP0003806_abnormal_nucleotide_metabolis0.54273536
145MP0003698_abnormal_male_reproductive0.54124705
146MP0001188_hyperpigmentation0.52560822
147MP0000467_abnormal_esophagus_morphology0.51855383
148MP0001664_abnormal_digestion0.48784710
149MP0001502_abnormal_circadian_rhythm0.48664529
150MP0001324_abnormal_eye_pigmentation0.46201172
151MP0001485_abnormal_pinna_reflex0.46063113
152MP0008004_abnormal_stomach_pH0.45441270
153MP0009703_decreased_birth_body0.42621293
154MP0002896_abnormal_bone_mineralization0.42541058
155MP0005076_abnormal_cell_differentiation0.41154290
156MP0002135_abnormal_kidney_morphology0.41131545
157MP0000249_abnormal_blood_vessel0.39875296
158MP0008873_increased_physiological_sensi0.38947499
159MP0006036_abnormal_mitochondrial_physio0.37735051

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)4.87336671
2Abnormal delayed hypersensitivity skin test (HP:0002963)4.64835514
3Recurrent sinusitis (HP:0011108)4.55486235
4Interstitial pulmonary disease (HP:0006530)4.55481483
5Chronic bronchitis (HP:0004469)4.38237094
6Infertility (HP:0000789)4.30751236
7Abnormal respiratory motile cilium physiology (HP:0012261)4.19358963
8Male infertility (HP:0003251)4.17529954
9Onycholysis (HP:0001806)3.88186039
10Hypothermia (HP:0002045)3.79403964
11Chronic sinusitis (HP:0011109)3.73420180
12Rhinitis (HP:0012384)3.64785696
13Bronchitis (HP:0012387)3.62504463
14Abnormal respiratory epithelium morphology (HP:0012253)3.58768154
15Abnormal respiratory motile cilium morphology (HP:0005938)3.58768154
16Bronchiectasis (HP:0002110)3.51830566
17Agammaglobulinemia (HP:0004432)3.45761863
18Nasal polyposis (HP:0100582)3.45528563
19Occipital encephalocele (HP:0002085)3.40689956
20Abnormality of the nasal mucosa (HP:0000433)3.40109497
21Dry hair (HP:0011359)3.36568254
22Elevated erythrocyte sedimentation rate (HP:0003565)3.35759312
23Pancreatic fibrosis (HP:0100732)3.13714300
24Recurrent bronchitis (HP:0002837)3.12016042
25Atelectasis (HP:0100750)3.11718341
26Progressive neurologic deterioration (HP:0002344)3.08428126
27True hermaphroditism (HP:0010459)3.06325151
28Abnormality of T cell physiology (HP:0011840)3.06324800
29Decreased circulating renin level (HP:0003351)3.00958673
30Abnormality of incisor morphology (HP:0011063)2.94243160
31Protuberant abdomen (HP:0001538)2.93139607
32Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.91204268
33Dynein arm defect of respiratory motile cilia (HP:0012255)2.85251391
34Absent/shortened dynein arms (HP:0200106)2.85251391
35Hyperactive renin-angiotensin system (HP:0000841)2.80564822
36Abnormality of aromatic amino acid family metabolism (HP:0004338)2.69590643
37Cystic liver disease (HP:0006706)2.62163145
38Abnormality of midbrain morphology (HP:0002418)2.54576477
39Molar tooth sign on MRI (HP:0002419)2.54576477
40Spastic paraparesis (HP:0002313)2.50379171
41Abnormal hair whorl (HP:0010721)2.49995098
42Dysostosis multiplex (HP:0000943)2.49783647
43Myositis (HP:0100614)2.48518957
44Nephronophthisis (HP:0000090)2.46285502
45Pancreatic cysts (HP:0001737)2.46145315
46Meningitis (HP:0001287)2.44425676
47Flat capital femoral epiphysis (HP:0003370)2.40195069
48Erythema (HP:0010783)2.38322472
49Recurrent otitis media (HP:0000403)2.37900469
50Chronic hepatic failure (HP:0100626)2.30449247
51Pulmonary infiltrates (HP:0002113)2.24177642
52Postaxial foot polydactyly (HP:0001830)2.22163525
53Gastrointestinal stroma tumor (HP:0100723)2.22029714
54Generalized aminoaciduria (HP:0002909)2.21150496
55Thrombocytosis (HP:0001894)2.16921076
56Chronic otitis media (HP:0000389)2.14927879
57Episodic fever (HP:0001954)2.13912057
58Death in childhood (HP:0003819)2.13335360
59Abnormality of glycolipid metabolism (HP:0010969)2.11184272
60Abnormality of liposaccharide metabolism (HP:0010968)2.11184272
61Abnormality of glycosphingolipid metabolism (HP:0004343)2.11184272
62Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.10865868
63IgM deficiency (HP:0002850)2.10416244
64Cerebral palsy (HP:0100021)2.10031345
65Type I transferrin isoform profile (HP:0003642)2.09229494
66Abnormality of the intrinsic pathway (HP:0010989)2.09006353
67Abnormality of renin-angiotensin system (HP:0000847)2.05488837
68Conical tooth (HP:0000698)2.03028706
69Bell-shaped thorax (HP:0001591)2.01918509
70Skin rash (HP:0000988)2.00909009
71Tubulointerstitial nephritis (HP:0001970)1.98387555
72Abdominal distention (HP:0003270)1.97935887
73Absent frontal sinuses (HP:0002688)1.94802555
74Prolonged partial thromboplastin time (HP:0003645)1.93198303
75Epiphyseal dysplasia (HP:0002656)1.92179051
76B lymphocytopenia (HP:0010976)1.92151928
77Abnormality of B cell number (HP:0010975)1.92151928
78Congenital hepatic fibrosis (HP:0002612)1.90281497
79Abnormality of the renal medulla (HP:0100957)1.89840791
80Abnormal protein glycosylation (HP:0012346)1.88797199
81Abnormal glycosylation (HP:0012345)1.88797199
82Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.88797199
83Abnormal protein N-linked glycosylation (HP:0012347)1.88797199
84Medial flaring of the eyebrow (HP:0010747)1.84362474
85Petechiae (HP:0000967)1.83414850
86Colitis (HP:0002583)1.83075559
87Urinary glycosaminoglycan excretion (HP:0003541)1.80433364
88Mucopolysacchariduria (HP:0008155)1.80433364
89Renal salt wasting (HP:0000127)1.79450416
90Anencephaly (HP:0002323)1.79417009
91Inflammation of the large intestine (HP:0002037)1.79308388
92Purpura (HP:0000979)1.77188691
93Cortical visual impairment (HP:0100704)1.74985873
94Congenital primary aphakia (HP:0007707)1.73703572
95Dehydration (HP:0001944)1.73339098
96Male pseudohermaphroditism (HP:0000037)1.72754528
97Recurrent pneumonia (HP:0006532)1.72516731
98Opisthotonus (HP:0002179)1.72407361
99Aplasia/Hypoplasia of the tongue (HP:0010295)1.71162209
100Asplenia (HP:0001746)1.70802481
101Gait imbalance (HP:0002141)1.70378798
102Ketoacidosis (HP:0001993)1.70179441
103Reduced antithrombin III activity (HP:0001976)1.70071560
104Joint stiffness (HP:0001387)1.69104459
105Abnormality of fatty-acid metabolism (HP:0004359)1.69015319
106Increased IgE level (HP:0003212)1.68348383
107Aplasia/Hypoplasia of the spleen (HP:0010451)1.68161249
108Periodontitis (HP:0000704)1.67628864
109Abnormality of T cells (HP:0002843)1.67521975
110Nephrogenic diabetes insipidus (HP:0009806)1.67260403
111Hepatocellular necrosis (HP:0001404)1.67052722
112Papilloma (HP:0012740)1.66257707
113Verrucae (HP:0200043)1.66257707
114Epiphyseal stippling (HP:0010655)1.66057466
115Hepatic necrosis (HP:0002605)1.66041333
116Restrictive lung disease (HP:0002091)1.65873740
117Hyperaldosteronism (HP:0000859)1.65532149
118Paraparesis (HP:0002385)1.65117150
119Cellulitis (HP:0100658)1.64733204
120Prolonged bleeding time (HP:0003010)1.63997273
121Generalized hypopigmentation of hair (HP:0011358)1.63285039
122Nephropathy (HP:0000112)1.62850309
123Hyperkalemia (HP:0002153)1.62641426
124Hypergammaglobulinemia (HP:0010702)1.62602947
125Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.62595555
126Lymphopenia (HP:0001888)1.62132626
127Oculomotor apraxia (HP:0000657)1.54391484
128Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.51733711
129Tubular atrophy (HP:0000092)1.50184479
130Furrowed tongue (HP:0000221)1.48105566
131Sclerocornea (HP:0000647)1.40094437
132Abnormality of chloride homeostasis (HP:0011422)1.38600369
133Hand muscle atrophy (HP:0009130)1.33836200
134Postaxial hand polydactyly (HP:0001162)1.33452180
135Abnormality of the distal phalanges of the toes (HP:0010182)1.28331768
136Fetal akinesia sequence (HP:0001989)1.27747144
137Absent rod-and cone-mediated responses on ERG (HP:0007688)1.27644845
138Short thorax (HP:0010306)1.26379340
139Glucose intolerance (HP:0000833)1.26100666
140Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.23133287
141Hypokalemic alkalosis (HP:0001949)1.21837606
142Hyponatremia (HP:0002902)1.21227245
143Abnormality of the frontal sinuses (HP:0002687)1.20680308
144Obstructive sleep apnea (HP:0002870)1.19773436
145Decreased central vision (HP:0007663)1.17542594
146Cone-rod dystrophy (HP:0000548)1.17495144
147Aplasia of the musculature (HP:0100854)1.17027915
148Popliteal pterygium (HP:0009756)1.16984114
149Abnormality of monocarboxylic acid metabolism (HP:0010996)1.15341324
150Median cleft lip (HP:0000161)1.13896313
151Short nail (HP:0001799)1.12488528
152Abnormality of permanent molar morphology (HP:0011071)1.11819709
153Abnormality of the dental root (HP:0006486)1.11819709
154Taurodontia (HP:0000679)1.11819709
155Muscle fiber splitting (HP:0003555)1.11061734
156Flat acetabular roof (HP:0003180)1.10151424
157Preaxial hand polydactyly (HP:0001177)1.09918293
158Bifid scrotum (HP:0000048)1.09049377
159Lip pit (HP:0100267)1.08849674
160Short femoral neck (HP:0100864)1.06894079
161Stage 5 chronic kidney disease (HP:0003774)1.06088100
162Tubulointerstitial abnormality (HP:0001969)1.05701970
163Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.03678660
164Abnormality of molar (HP:0011077)1.01857747
165Abnormality of molar morphology (HP:0011070)1.01857747
166Abnormality of the dental pulp (HP:0006479)0.99501520
167Upper limb amyotrophy (HP:0009129)0.99015718
168Distal upper limb amyotrophy (HP:0007149)0.99015718
169Poor coordination (HP:0002370)0.98915067
170Stridor (HP:0010307)0.97644152
171Self-mutilation (HP:0000742)0.97088084
172Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)0.96972493
173Spinal muscular atrophy (HP:0007269)0.96956044
174Carpal bone hypoplasia (HP:0001498)0.93372237

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA24.70796153
2MAPK154.57793295
3ERN14.06850487
4INSRR3.53382045
5ARAF3.36741125
6MST42.97864931
7IKBKE2.71940975
8MAP4K12.63623841
9MAP3K132.61923750
10SMG12.48491726
11PIM22.44776610
12MAP3K122.44624377
13MAP3K142.34339957
14MAPKAPK32.05591179
15TAOK32.01554353
16EEF2K1.85293059
17BCKDK1.65601356
18TGFBR21.56202673
19TTK1.55951147
20CSF1R1.55044402
21TESK11.54059228
22NME21.52184272
23TNIK1.50498380
24TBK11.50430089
25KIT1.49017229
26TEC1.38674430
27EPHB11.36763595
28CASK1.36231663
29CDK191.35752017
30TYK21.31397264
31PTK2B1.29569754
32BRAF1.27172763
33CAMKK21.25719208
34SRPK11.25690595
35IRAK31.24944123
36STK101.24919722
37SYK1.23127956
38DAPK21.20460394
39BCR1.16791480
40RPS6KA21.15379734
41PIK3CA1.13446684
42PRKCH1.12849208
43MARK21.11710609
44MST1R1.11036110
45BMPR21.09021680
46IKBKB1.08784762
47MAP3K31.05795647
48PIK3CG1.04524786
49TRIB31.04319449
50FGFR41.01674994
51EPHA31.00892785
52LIMK10.99784424
53IRAK40.98780459
54TRPM70.95841229
55GRK10.93496150
56ZAP700.92033829
57MAPKAPK50.90788343
58ICK0.90727212
59PRKCI0.89609705
60MAP3K20.87108622
61BTK0.87045107
62BLK0.86702677
63GRK60.84326120
64GRK70.83366720
65MAP2K70.80657385
66ERBB30.80468636
67ITK0.80334260
68RPS6KL10.79630963
69RPS6KC10.79630963
70HIPK20.78957602
71MYLK0.78526663
72JAK10.78524079
73MAPK70.74850292
74FLT30.74108690
75STK380.73336613
76CAMKK10.72247631
77RAF10.72203150
78MAP3K10.70396649
79NME10.70378072
80MUSK0.70107495
81TXK0.69215961
82LYN0.68342246
83MAPK40.68144845
84FRK0.67976990
85RPS6KA60.67770425
86BRD40.67723065
87RIPK10.65085629
88STK160.62636917
89FES0.62497681
90PRKCQ0.61812234
91TAOK10.61512986
92ERBB20.60651151
93PNCK0.57171798
94NEK60.55839606
95PDPK10.54391169
96RIPK40.53525589
97LRRK20.53398059
98AKT30.53317692
99FGFR30.53306505
100MAPK130.52821855
101CAMK40.49807099
102LCK0.49593396
103CHUK0.49467179
104BRSK20.49368660
105DYRK1B0.49160008
106CDC42BPA0.49061664
107SGK20.48085825
108IRAK10.46908340
109PRKCE0.46733740
110STK240.45695752
111PRKAA20.43986236
112MAP2K20.43842321
113PRKCD0.43739539
114CSK0.42248964
115TLK10.41484758
116DYRK1A0.41086994
117CDK60.40450293
118MAPK120.40300975
119MAP3K110.40075056
120SGK10.39838462
121MAP3K70.39636143
122PTK60.38183083
123NLK0.37537939
124GRK50.37363401
125YES10.36929982
126PAK40.36114005
127CAMK2G0.35045366
128AURKA0.34748376
129RPS6KB20.34395482
130NTRK30.34119500
131MAPK30.33907825
132PDK10.32271155
133EIF2AK20.32237210
134MAP2K40.26058546
135MATK0.23771622
136PBK0.23624761
137MAP2K30.23602065
138PRKD20.22126498
139ABL10.21420630
140FYN0.21128529
141CDK120.17788599
142RET0.17637624
143AKT20.17446297
144ROCK20.17337514
145MAP3K60.16116363
146NEK90.16049784
147ADRBK10.14874619
148MET0.14665328
149PRKCA0.13777886
150SRC0.13530015
151FER0.12945301
152PAK10.12651651
153PRKACA0.12306275
154ROCK10.11792940
155EGFR0.11767270
156MAP3K80.11389465
157MELK0.10894296
158MAP3K40.08970410
159STK110.08863959
160KSR20.08102331

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030605.53986506
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.54432889
3SNARE interactions in vesicular transport_Homo sapiens_hsa041302.73239858
4Sulfur metabolism_Homo sapiens_hsa009202.42556490
5Huntingtons disease_Homo sapiens_hsa050162.37249551
6Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.25532137
7Folate biosynthesis_Homo sapiens_hsa007902.22033973
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.03634910
9Primary immunodeficiency_Homo sapiens_hsa053402.03170488
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.85961576
11Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.78206635
12Histidine metabolism_Homo sapiens_hsa003401.74876664
13Primary bile acid biosynthesis_Homo sapiens_hsa001201.74786519
14Other glycan degradation_Homo sapiens_hsa005111.73674460
15Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.71481647
16beta-Alanine metabolism_Homo sapiens_hsa004101.69887432
17Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.68566668
18Linoleic acid metabolism_Homo sapiens_hsa005911.67544117
19Fatty acid degradation_Homo sapiens_hsa000711.65095795
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64168891
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.60204866
22Vibrio cholerae infection_Homo sapiens_hsa051101.59461975
23Tryptophan metabolism_Homo sapiens_hsa003801.56654858
24Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.55180340
25N-Glycan biosynthesis_Homo sapiens_hsa005101.48769297
26Collecting duct acid secretion_Homo sapiens_hsa049661.40580871
27Fatty acid elongation_Homo sapiens_hsa000621.40499136
28Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.37679755
29Lysosome_Homo sapiens_hsa041421.37020725
30Hematopoietic cell lineage_Homo sapiens_hsa046401.36378804
31Peroxisome_Homo sapiens_hsa041461.33242018
32Pentose and glucuronate interconversions_Homo sapiens_hsa000401.32814564
33Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.26247520
34Steroid hormone biosynthesis_Homo sapiens_hsa001401.25890795
35Tight junction_Homo sapiens_hsa045301.25492199
36Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.24321670
37Phenylalanine metabolism_Homo sapiens_hsa003601.21594234
38B cell receptor signaling pathway_Homo sapiens_hsa046621.20509842
39RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.20483013
40Carbohydrate digestion and absorption_Homo sapiens_hsa049731.19673162
41Rheumatoid arthritis_Homo sapiens_hsa053231.11122105
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.10324991
43Tyrosine metabolism_Homo sapiens_hsa003501.09542337
44Chemical carcinogenesis_Homo sapiens_hsa052041.06479594
45Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02133717
46Proteasome_Homo sapiens_hsa030501.01711816
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.01656898
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.00450429
49Circadian rhythm_Homo sapiens_hsa047100.96058109
50Oxidative phosphorylation_Homo sapiens_hsa001900.95238520
51Selenocompound metabolism_Homo sapiens_hsa004500.94320980
52Leukocyte transendothelial migration_Homo sapiens_hsa046700.94302904
53Arachidonic acid metabolism_Homo sapiens_hsa005900.93542446
54Ribosome_Homo sapiens_hsa030100.93296090
55Sphingolipid metabolism_Homo sapiens_hsa006000.92541313
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91629157
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.90077527
58Notch signaling pathway_Homo sapiens_hsa043300.89657373
59Galactose metabolism_Homo sapiens_hsa000520.89446938
60Propanoate metabolism_Homo sapiens_hsa006400.87780580
61Fatty acid metabolism_Homo sapiens_hsa012120.86006995
62Pyruvate metabolism_Homo sapiens_hsa006200.85722785
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.84155147
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84111747
65Glycosaminoglycan degradation_Homo sapiens_hsa005310.80824515
66Complement and coagulation cascades_Homo sapiens_hsa046100.80299628
67Salivary secretion_Homo sapiens_hsa049700.79707499
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79494704
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.79351353
70Hepatitis C_Homo sapiens_hsa051600.79210276
71Choline metabolism in cancer_Homo sapiens_hsa052310.78289936
72Phagosome_Homo sapiens_hsa041450.75708510
73Phototransduction_Homo sapiens_hsa047440.74575699
74Osteoclast differentiation_Homo sapiens_hsa043800.73270485
75Pertussis_Homo sapiens_hsa051330.72890237
76ABC transporters_Homo sapiens_hsa020100.72794140
77Butanoate metabolism_Homo sapiens_hsa006500.71135999
78Taste transduction_Homo sapiens_hsa047420.70924311
79Steroid biosynthesis_Homo sapiens_hsa001000.69351427
80Toll-like receptor signaling pathway_Homo sapiens_hsa046200.67685962
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64441552
82Retinol metabolism_Homo sapiens_hsa008300.64164358
83Glycerophospholipid metabolism_Homo sapiens_hsa005640.63828081
84Glutathione metabolism_Homo sapiens_hsa004800.63621214
85Insulin secretion_Homo sapiens_hsa049110.62444314
86Antigen processing and presentation_Homo sapiens_hsa046120.62233752
87Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.62074515
88Starch and sucrose metabolism_Homo sapiens_hsa005000.61183907
89Staphylococcus aureus infection_Homo sapiens_hsa051500.57536375
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57104343
91Adherens junction_Homo sapiens_hsa045200.57021454
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.56421865
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.55283903
94Allograft rejection_Homo sapiens_hsa053300.54922919
95Leishmaniasis_Homo sapiens_hsa051400.54563427
96Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54050633
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53901376
98Influenza A_Homo sapiens_hsa051640.53574250
99Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.53071733
100Alzheimers disease_Homo sapiens_hsa050100.51606801
101Autoimmune thyroid disease_Homo sapiens_hsa053200.48393283
102Renin secretion_Homo sapiens_hsa049240.48252075
103Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47956175
104Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47187397
105Type I diabetes mellitus_Homo sapiens_hsa049400.47077785
106Graft-versus-host disease_Homo sapiens_hsa053320.47035502
107Amoebiasis_Homo sapiens_hsa051460.46295714
108Amphetamine addiction_Homo sapiens_hsa050310.46254476
109PPAR signaling pathway_Homo sapiens_hsa033200.46244558
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46005629
111Measles_Homo sapiens_hsa051620.45757247
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41993255
113Drug metabolism - other enzymes_Homo sapiens_hsa009830.40943053
114Metabolic pathways_Homo sapiens_hsa011000.39909605
115Caffeine metabolism_Homo sapiens_hsa002320.39638361
116Insulin resistance_Homo sapiens_hsa049310.38324490
117Hedgehog signaling pathway_Homo sapiens_hsa043400.38222096
118Acute myeloid leukemia_Homo sapiens_hsa052210.37673308
119Olfactory transduction_Homo sapiens_hsa047400.36915170
120Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.35955062
121Aldosterone synthesis and secretion_Homo sapiens_hsa049250.35222288
122Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.34711018
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.33864846
124Phosphatidylinositol signaling system_Homo sapiens_hsa040700.31653875
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.31501433
126Asthma_Homo sapiens_hsa053100.31355206
127Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31271903
128Legionellosis_Homo sapiens_hsa051340.30850415
129Cocaine addiction_Homo sapiens_hsa050300.30229743
130Vitamin digestion and absorption_Homo sapiens_hsa049770.29922870
131Fructose and mannose metabolism_Homo sapiens_hsa000510.27346358
132Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25269004
133Cyanoamino acid metabolism_Homo sapiens_hsa004600.24641569
134Endocytosis_Homo sapiens_hsa041440.24282580
135Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.23908801
136Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.22394861
137cAMP signaling pathway_Homo sapiens_hsa040240.20940776
138Basal cell carcinoma_Homo sapiens_hsa052170.19090331
139Apoptosis_Homo sapiens_hsa042100.19023528
140Tuberculosis_Homo sapiens_hsa051520.18451113
141Prostate cancer_Homo sapiens_hsa052150.16752542
142Pancreatic cancer_Homo sapiens_hsa052120.16161259
143TNF signaling pathway_Homo sapiens_hsa046680.14752711
144Glycerolipid metabolism_Homo sapiens_hsa005610.14617452
145Fatty acid biosynthesis_Homo sapiens_hsa000610.09338749
146Salmonella infection_Homo sapiens_hsa051320.09185723
147Arginine and proline metabolism_Homo sapiens_hsa003300.08375966
148Toxoplasmosis_Homo sapiens_hsa051450.07702873
149Bile secretion_Homo sapiens_hsa049760.06544989

Most similar genes based on co-expression Upload to Enrichr

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