CCDC173

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.31396950
2cilium movement (GO:0003341)8.94553956
3multicellular organism reproduction (GO:0032504)8.61641569
4cell wall macromolecule metabolic process (GO:0044036)8.44778539
5cell wall macromolecule catabolic process (GO:0016998)8.44778539
6acrosome assembly (GO:0001675)8.37424375
7epithelial cilium movement (GO:0003351)8.24905808
8fusion of sperm to egg plasma membrane (GO:0007342)7.76800742
9sperm-egg recognition (GO:0035036)7.13291256
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.84587428
11sperm motility (GO:0030317)6.80504214
12reproduction (GO:0000003)6.47290031
13motile cilium assembly (GO:0044458)6.38851176
14cell-cell recognition (GO:0009988)6.33456134
15acrosome reaction (GO:0007340)6.18099797
16plasma membrane fusion (GO:0045026)5.93138005
17male meiosis (GO:0007140)5.91384839
18ventricular system development (GO:0021591)5.71407362
19binding of sperm to zona pellucida (GO:0007339)5.55920732
20intraciliary transport (GO:0042073)5.50866913
21regulation of cilium movement (GO:0003352)5.49732248
22axoneme assembly (GO:0035082)5.39551865
23spermatid development (GO:0007286)5.30227117
24sperm capacitation (GO:0048240)5.28786721
25single fertilization (GO:0007338)5.28643864
26piRNA metabolic process (GO:0034587)4.84847649
27neuron fate determination (GO:0048664)4.79808505
28cilium organization (GO:0044782)4.61836372
29cilium assembly (GO:0042384)4.50565609
30somite development (GO:0061053)4.48396720
31spermatid nucleus differentiation (GO:0007289)4.39598624
32synaptonemal complex organization (GO:0070193)4.16100993
33protein localization to cilium (GO:0061512)4.08823442
34fertilization (GO:0009566)4.04464337
35left/right axis specification (GO:0070986)4.00556479
36centriole assembly (GO:0098534)3.98839084
37male meiosis I (GO:0007141)3.97356891
38microtubule depolymerization (GO:0007019)3.96328787
39forebrain neuron differentiation (GO:0021879)3.94021776
40synaptonemal complex assembly (GO:0007130)3.89546577
41DNA methylation involved in gamete generation (GO:0043046)3.83098869
42protein polyglutamylation (GO:0018095)3.82893262
43cellular component assembly involved in morphogenesis (GO:0010927)3.82403358
44cilium morphogenesis (GO:0060271)3.75641957
45GTP biosynthetic process (GO:0006183)3.70966467
46microtubule severing (GO:0051013)3.68714582
47centriole replication (GO:0007099)3.66219047
48neuronal stem cell maintenance (GO:0097150)3.64252694
49positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.62137663
50microtubule polymerization or depolymerization (GO:0031109)3.59053263
51cell recognition (GO:0008037)3.54051195
52retinal rod cell development (GO:0046548)3.49659906
53determination of bilateral symmetry (GO:0009855)3.47337287
54pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.44206216
55specification of symmetry (GO:0009799)3.39136077
56chromosome organization involved in meiosis (GO:0070192)3.31153820
57positive regulation of neuroblast proliferation (GO:0002052)3.30933211
58base-excision repair, AP site formation (GO:0006285)3.29769980
59calcium ion-dependent exocytosis (GO:0017156)3.27155039
60spermatogenesis (GO:0007283)3.23659666
61male gamete generation (GO:0048232)3.22535417
62axon ensheathment in central nervous system (GO:0032291)3.21444643
63central nervous system myelination (GO:0022010)3.21444643
64cell proliferation in forebrain (GO:0021846)3.20044955
65regulation of DNA endoreduplication (GO:0032875)3.18668932
66synapsis (GO:0007129)3.14122911
67nonmotile primary cilium assembly (GO:0035058)3.13660199
68tongue development (GO:0043586)3.07434991
69nucleoside diphosphate phosphorylation (GO:0006165)3.06551186
70meiotic nuclear division (GO:0007126)3.05806165
71gamete generation (GO:0007276)3.02554155
72cellular process involved in reproduction in multicellular organism (GO:0022412)3.02545178
73meiosis I (GO:0007127)2.96000967
74protein K11-linked deubiquitination (GO:0035871)2.95724466
75protein K6-linked ubiquitination (GO:0085020)2.94597739
76calcium ion import (GO:0070509)2.94244386
77behavioral response to nicotine (GO:0035095)2.90733394
78regulation of inositol phosphate biosynthetic process (GO:0010919)2.89886191
79UTP biosynthetic process (GO:0006228)2.89193883
80cellular response to gamma radiation (GO:0071480)2.88827485
81germ cell development (GO:0007281)2.87683250
82pyrimidine nucleotide catabolic process (GO:0006244)2.84696842
83histone H3-K9 methylation (GO:0051567)2.83931647
84nephron tubule morphogenesis (GO:0072078)2.80707780
85nephron epithelium morphogenesis (GO:0072088)2.80707780
86pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.77001159
87negative regulation of transcription regulatory region DNA binding (GO:2000678)2.76687555
88negative regulation of oligodendrocyte differentiation (GO:0048715)2.76604288
89dorsal/ventral pattern formation (GO:0009953)2.76451363
90lateral sprouting from an epithelium (GO:0060601)2.75262328
91substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.74430222
92substrate-independent telencephalic tangential migration (GO:0021826)2.74430222
93guanosine-containing compound biosynthetic process (GO:1901070)2.73496795
94microtubule-based movement (GO:0007018)2.72582602
95retinal cone cell development (GO:0046549)2.72318111
96left/right pattern formation (GO:0060972)2.71547070
97cell projection assembly (GO:0030031)2.69838421
98telencephalon development (GO:0021537)2.66930602
99negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.56025980
100regulation of microtubule-based movement (GO:0060632)2.55585984
101histone H3-K9 modification (GO:0061647)2.53424987
102retinal ganglion cell axon guidance (GO:0031290)2.53193146
103negative regulation of inclusion body assembly (GO:0090084)2.53104313
104heart looping (GO:0001947)2.49900389
105positive regulation of gastrulation (GO:2000543)2.43786664
106cochlea development (GO:0090102)2.43700097
107transmission of nerve impulse (GO:0019226)2.43006455
108hindbrain development (GO:0030902)2.40621187
109negative regulation of astrocyte differentiation (GO:0048712)2.40525412
110establishment of protein localization to mitochondrial membrane (GO:0090151)2.39181455
111regulation of development, heterochronic (GO:0040034)2.38044772
112CTP metabolic process (GO:0046036)2.37964705
113CTP biosynthetic process (GO:0006241)2.37964705
114microtubule-based process (GO:0007017)2.37706734
115photoreceptor cell maintenance (GO:0045494)2.37689571
116organic cation transport (GO:0015695)2.36984939
117poly(A)+ mRNA export from nucleus (GO:0016973)2.36497833
118regulation of mesenchymal cell apoptotic process (GO:2001053)2.36396155
119organelle assembly (GO:0070925)2.36226356
120embryonic heart tube morphogenesis (GO:0003143)2.33411816
121cell-cell signaling involved in cell fate commitment (GO:0045168)2.33006739
122microtubule bundle formation (GO:0001578)2.31532186
123keratinocyte development (GO:0003334)2.31281835
124multicellular organismal reproductive process (GO:0048609)2.30811548
125female gonad development (GO:0008585)2.30127543
126regulation of timing of cell differentiation (GO:0048505)2.29501907
127pyrimidine nucleobase catabolic process (GO:0006208)2.29188352
128smoothened signaling pathway (GO:0007224)2.28788270
129cerebral cortex radially oriented cell migration (GO:0021799)2.27927751
130limb bud formation (GO:0060174)2.26454355
131meiotic cell cycle (GO:0051321)2.26245981
132UTP metabolic process (GO:0046051)2.26032161
133single strand break repair (GO:0000012)2.25879043
134presynaptic membrane assembly (GO:0097105)2.25874183
135regulation of neuroblast proliferation (GO:1902692)2.25534882
136regulation of collateral sprouting (GO:0048670)2.25504760
137eye photoreceptor cell development (GO:0042462)2.24621283
138otic vesicle formation (GO:0030916)2.23502674
139radial glial cell differentiation (GO:0060019)2.22670510
140retina layer formation (GO:0010842)2.22215971
141inner ear morphogenesis (GO:0042472)2.20032658
142spinal cord motor neuron differentiation (GO:0021522)2.19116128
143detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.18896541
144startle response (GO:0001964)2.18533054
145determination of left/right symmetry (GO:0007368)2.18177971
146pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.17189063
147limb development (GO:0060173)2.17163413
148appendage development (GO:0048736)2.17163413
149mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.16710811
150activated T cell proliferation (GO:0050798)2.16678059
151spinal cord development (GO:0021510)2.16015251
152spinal cord association neuron differentiation (GO:0021527)2.15615784
153photoreceptor cell development (GO:0042461)2.14704105
154cilium or flagellum-dependent cell motility (GO:0001539)11.0113775

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.99729068
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.43304939
3PCGF2_27294783_Chip-Seq_ESCs_Mouse3.22559837
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.07534575
5FLI1_27457419_Chip-Seq_LIVER_Mouse3.05924348
6EZH2_22144423_ChIP-Seq_EOC_Human3.01714334
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.87952403
8GBX2_23144817_ChIP-Seq_PC3_Human2.85989844
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.73832560
10CBX2_27304074_Chip-Seq_ESCs_Mouse2.72842079
11PCGF2_27294783_Chip-Seq_NPCs_Mouse2.51068327
12SUZ12_27294783_Chip-Seq_NPCs_Mouse2.47918231
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44203126
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.41310466
15NFE2_27457419_Chip-Seq_LIVER_Mouse2.32458037
16RNF2_27304074_Chip-Seq_NSC_Mouse2.20985328
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.16440198
18NANOG_18555785_Chip-Seq_ESCs_Mouse2.11491203
19TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse2.09171434
20EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse2.09162437
21POU3F2_20337985_ChIP-ChIP_501MEL_Human2.01663850
22EZH2_27294783_Chip-Seq_NPCs_Mouse2.00754708
23P53_22387025_ChIP-Seq_ESCs_Mouse1.97795010
24VDR_22108803_ChIP-Seq_LS180_Human1.96528626
25SUZ12_18555785_Chip-Seq_ESCs_Mouse1.96483780
26BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.96300819
27STAT3_18555785_Chip-Seq_ESCs_Mouse1.95369165
28EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.92641908
29TAF15_26573619_Chip-Seq_HEK293_Human1.90278584
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89321338
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89233957
32E2F1_18555785_Chip-Seq_ESCs_Mouse1.87844042
33CMYC_18555785_Chip-Seq_ESCs_Mouse1.86795627
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.86063709
35P300_18555785_Chip-Seq_ESCs_Mouse1.85847594
36OCT4_18555785_Chip-Seq_ESCs_Mouse1.82142882
37RUNX1_27457419_Chip-Seq_LIVER_Mouse1.79837347
38KLF4_18555785_Chip-Seq_ESCs_Mouse1.75117093
39SOX2_18555785_Chip-Seq_ESCs_Mouse1.74541674
40NMYC_18555785_Chip-Seq_ESCs_Mouse1.71943601
41ESRRB_18555785_Chip-Seq_ESCs_Mouse1.71672181
42ZFX_18555785_Chip-Seq_ESCs_Mouse1.67904565
43P300_19829295_ChIP-Seq_ESCs_Human1.66555165
44CTCF_18555785_Chip-Seq_ESCs_Mouse1.65122058
45EED_16625203_ChIP-ChIP_MESCs_Mouse1.63672051
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.62979499
47RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.61549426
48TAL1_26923725_Chip-Seq_HPCs_Mouse1.56457194
49CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56330299
50HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.56185655
51SMAD1_18555785_Chip-Seq_ESCs_Mouse1.55726047
52KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.55277236
53FUS_26573619_Chip-Seq_HEK293_Human1.55186190
54CRX_20693478_ChIP-Seq_RETINA_Mouse1.54954924
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.52980234
56AR_21572438_ChIP-Seq_LNCaP_Human1.51107038
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.50687147
58PU1_27457419_Chip-Seq_LIVER_Mouse1.49859868
59TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48281022
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.48220032
61ER_23166858_ChIP-Seq_MCF-7_Human1.48171296
62SUZ12_27294783_Chip-Seq_ESCs_Mouse1.46327486
63POU5F1_16153702_ChIP-ChIP_HESCs_Human1.45627448
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45298690
65OCT4_21477851_ChIP-Seq_ESCs_Mouse1.44950649
66MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43307146
67CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43280482
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.42432531
69KAP1_22055183_ChIP-Seq_ESCs_Mouse1.41362279
70KDM2B_26808549_Chip-Seq_REH_Human1.40046053
71EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.38777396
72RNF2_27304074_Chip-Seq_ESCs_Mouse1.36892011
73JARID2_20075857_ChIP-Seq_MESCs_Mouse1.35582271
74NR3C1_21868756_ChIP-Seq_MCF10A_Human1.35580503
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.32395488
76CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.31942426
77DROSHA_22980978_ChIP-Seq_HELA_Human1.30853009
78SMAD4_21799915_ChIP-Seq_A2780_Human1.30687650
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.29057926
80GABP_17652178_ChIP-ChIP_JURKAT_Human1.28754153
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27715223
82TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27715223
83SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.27184345
84SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.25288430
85SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.23607694
86TCF4_22108803_ChIP-Seq_LS180_Human1.23184911
87IGF1R_20145208_ChIP-Seq_DFB_Human1.22807535
88CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.22153352
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.22097901
90MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.21617184
91WDR5_24793694_ChIP-Seq_LNCAP_Human1.20150510
92EWS_26573619_Chip-Seq_HEK293_Human1.19709489
93SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.19394893
94TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19374607
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19247888
96RUNX2_22187159_ChIP-Seq_PCA_Human1.17358415
97PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.16918826
98CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.15728555
99ZNF274_21170338_ChIP-Seq_K562_Hela1.13442436
100SMAD3_21741376_ChIP-Seq_EPCs_Human1.13217877
101PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.12976879
102BCAT_22108803_ChIP-Seq_LS180_Human1.11532003
103CDX2_19796622_ChIP-Seq_MESCs_Mouse1.10835152
104REST_21632747_ChIP-Seq_MESCs_Mouse1.10570200
105TCF4_23295773_ChIP-Seq_U87_Human1.10040877
106TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09234772
107PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.09107867
108BP1_19119308_ChIP-ChIP_Hs578T_Human1.09075498
109STAT1_17558387_ChIP-Seq_HELA_Human1.07886069
110EZH2_27304074_Chip-Seq_ESCs_Mouse1.07496423
111TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.07465485
112STAT3_23295773_ChIP-Seq_U87_Human1.06207109
113FLI1_21867929_ChIP-Seq_TH2_Mouse1.05960096
114KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05687304
115CBP_20019798_ChIP-Seq_JUKART_Human1.04590775
116IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04590775
117NANOG_19829295_ChIP-Seq_ESCs_Human1.03475833
118SOX2_19829295_ChIP-Seq_ESCs_Human1.03475833
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03292642
120AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.02283765
121EZH2_18974828_ChIP-Seq_MESCs_Mouse1.01929402
122RNF2_18974828_ChIP-Seq_MESCs_Mouse1.01929402
123SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.00372121
124JUN_21703547_ChIP-Seq_K562_Human0.99554697
125EZH2_27294783_Chip-Seq_ESCs_Mouse0.98208902
126SOX2_18555785_ChIP-Seq_MESCs_Mouse0.98079709
127FOXM1_26456572_ChIP-Seq_MCF-7_Human0.97342819
128FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97119160
129FOXA1_25329375_ChIP-Seq_VCAP_Human0.97119160
130AR_20517297_ChIP-Seq_VCAP_Human0.96770985
131LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96430101
132RING1B_27294783_Chip-Seq_ESCs_Mouse0.95956117
133SMAD4_21741376_ChIP-Seq_EPCs_Human0.95787755
134HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94587278
135GATA3_21878914_ChIP-Seq_MCF-7_Human0.94313209
136GATA1_26923725_Chip-Seq_HPCs_Mouse0.94205023
137SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.93849913
138TP53_22573176_ChIP-Seq_HFKS_Human0.93268729
139FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92950723
140OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92306051
141PHF8_20622853_ChIP-Seq_HELA_Human0.92020290
142ETV1_20927104_ChIP-Seq_GIST48_Human0.91950113
143SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91517734
144MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91217784
145GF1_26923725_Chip-Seq_HPCs_Mouse0.89747995
146SALL1_21062744_ChIP-ChIP_HESCs_Human0.89121964
147AR_25329375_ChIP-Seq_VCAP_Human0.89067477
148JARID2_20064375_ChIP-Seq_MESCs_Mouse0.88984979

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization6.17250078
2MP0003136_yellow_coat_color3.32349839
3MP0006292_abnormal_olfactory_placode3.02120326
4MP0003698_abnormal_male_reproductive2.94948331
5MP0008877_abnormal_DNA_methylation2.91584471
6MP0001188_hyperpigmentation2.60879394
7MP0002234_abnormal_pharynx_morphology2.60644854
8MP0000566_synostosis2.55953706
9MP0001929_abnormal_gametogenesis2.54649992
10MP0009379_abnormal_foot_pigmentation2.51815470
11MP0002653_abnormal_ependyma_morphology2.51685018
12MP0005646_abnormal_pituitary_gland2.39742911
13MP0008058_abnormal_DNA_repair2.33642562
14MP0005379_endocrine/exocrine_gland_phen2.32532029
15MP0001986_abnormal_taste_sensitivity2.25843798
16MP0002282_abnormal_trachea_morphology2.11917261
17MP0002102_abnormal_ear_morphology2.09690073
18MP0001984_abnormal_olfaction2.08780671
19MP0009046_muscle_twitch2.08763690
20MP0002210_abnormal_sex_determination2.05828176
21MP0005645_abnormal_hypothalamus_physiol2.04567187
22MP0002638_abnormal_pupillary_reflex2.03994441
23MP0004885_abnormal_endolymph2.01908298
24MP0003787_abnormal_imprinting1.98837850
25MP0009697_abnormal_copulation1.90484275
26MP0010030_abnormal_orbit_morphology1.89582166
27MP0008057_abnormal_DNA_replication1.89151484
28MP0005171_absent_coat_pigmentation1.88321644
29MP0003941_abnormal_skin_development1.86327361
30MP0003122_maternal_imprinting1.83997925
31MP0002277_abnormal_respiratory_mucosa1.83296939
32MP0003880_abnormal_central_pattern1.80839630
33MP0006276_abnormal_autonomic_nervous1.70122486
34MP0008875_abnormal_xenobiotic_pharmacok1.65788907
35MP0002163_abnormal_gland_morphology1.62705492
36MP0002928_abnormal_bile_duct1.61077780
37MP0001145_abnormal_male_reproductive1.55642318
38MP0002876_abnormal_thyroid_physiology1.52748435
39MP0000015_abnormal_ear_pigmentation1.49078509
40MP0005551_abnormal_eye_electrophysiolog1.47323569
41MP0000383_abnormal_hair_follicle1.46886197
42MP0005409_darkened_coat_color1.45099841
43MP0000653_abnormal_sex_gland1.44369371
44MP0005423_abnormal_somatic_nervous1.42261438
45MP0002161_abnormal_fertility/fecundity1.39896711
46MP0005623_abnormal_meninges_morphology1.37611754
47MP0002132_abnormal_respiratory_system1.37529547
48MP0010386_abnormal_urinary_bladder1.36024416
49MP0005253_abnormal_eye_physiology1.33227595
50MP0005174_abnormal_tail_pigmentation1.31213478
51MP0004742_abnormal_vestibular_system1.27421255
52MP0004381_abnormal_hair_follicle1.24052850
53MP0002736_abnormal_nociception_after1.22452944
54MP0006072_abnormal_retinal_apoptosis1.21827807
55MP0002822_catalepsy1.21420652
56MP0000631_abnormal_neuroendocrine_gland1.20836939
57MP0003890_abnormal_embryonic-extraembry1.20419163
58MP0000026_abnormal_inner_ear1.19499146
59MP0000049_abnormal_middle_ear1.17039964
60MP0008995_early_reproductive_senescence1.15413343
61MP0001486_abnormal_startle_reflex1.12832371
62MP0000778_abnormal_nervous_system1.12500996
63MP0009780_abnormal_chondrocyte_physiolo1.09685835
64MP0005195_abnormal_posterior_eye1.09258711
65MP0008789_abnormal_olfactory_epithelium1.08942048
66MP0000955_abnormal_spinal_cord1.06366985
67MP0004043_abnormal_pH_regulation1.04532461
68MP0003938_abnormal_ear_development1.04358765
69MP0002095_abnormal_skin_pigmentation1.03044247
70MP0002557_abnormal_social/conspecific_i1.03016209
71MP0001963_abnormal_hearing_physiology1.00540073
72MP0001968_abnormal_touch/_nociception1.00160931
73MP0002572_abnormal_emotion/affect_behav0.98893605
74MP0002735_abnormal_chemical_nociception0.98865816
75MP0005084_abnormal_gallbladder_morpholo0.98533298
76MP0001346_abnormal_lacrimal_gland0.97458142
77MP0001286_abnormal_eye_development0.97341357
78MP0001485_abnormal_pinna_reflex0.95606239
79MP0009745_abnormal_behavioral_response0.94220017
80MP0005499_abnormal_olfactory_system0.94213705
81MP0005394_taste/olfaction_phenotype0.94213705
82MP0001905_abnormal_dopamine_level0.93903744
83MP0001502_abnormal_circadian_rhythm0.93607412
84MP0001501_abnormal_sleep_pattern0.93231008
85MP0009250_abnormal_appendicular_skeleto0.92844462
86MP0001324_abnormal_eye_pigmentation0.92205845
87MP0002249_abnormal_larynx_morphology0.91927931
88MP0005389_reproductive_system_phenotype0.90411661
89MP0003861_abnormal_nervous_system0.90112521
90MP0005075_abnormal_melanosome_morpholog0.89890740
91MP0000678_abnormal_parathyroid_gland0.88832838
92MP0002160_abnormal_reproductive_system0.87933552
93MP0002938_white_spotting0.87884919
94MP0003183_abnormal_peptide_metabolism0.87102921
95MP0000681_abnormal_thyroid_gland0.86608454
96MP0005647_abnormal_sex_gland0.85434990
97MP0004133_heterotaxia0.84942760
98MP0001293_anophthalmia0.84809997
99MP0001119_abnormal_female_reproductive0.83100656
100MP0000428_abnormal_craniofacial_morphol0.83003823
101MP0001919_abnormal_reproductive_system0.82680766
102MP0002064_seizures0.82543195
103MP0001440_abnormal_grooming_behavior0.82457428
104MP0001299_abnormal_eye_distance/0.81902957
105MP0003755_abnormal_palate_morphology0.81550826
106MP0002152_abnormal_brain_morphology0.80618501
107MP0004019_abnormal_vitamin_homeostasis0.80579966
108MP0002272_abnormal_nervous_system0.79052841
109MP0000372_irregular_coat_pigmentation0.78918371
110MP0000647_abnormal_sebaceous_gland0.78448297
111MP0002882_abnormal_neuron_morphology0.78261054
112MP0002067_abnormal_sensory_capabilities0.78005267
113MP0009053_abnormal_anal_canal0.77857136
114MP0004134_abnormal_chest_morphology0.77312024
115MP0001529_abnormal_vocalization0.76792783
116MP0003121_genomic_imprinting0.76302189
117MP0003786_premature_aging0.74568719
118MP0003718_maternal_effect0.74540507
119MP0005187_abnormal_penis_morphology0.74422293
120MP0002734_abnormal_mechanical_nocicepti0.74252777
121MP0002752_abnormal_somatic_nervous0.74144953
122MP0003878_abnormal_ear_physiology0.73913324
123MP0005377_hearing/vestibular/ear_phenot0.73913324
124MP0003119_abnormal_digestive_system0.73284817
125MP0005391_vision/eye_phenotype0.73024645
126MP0010678_abnormal_skin_adnexa0.71395479
127MP0003635_abnormal_synaptic_transmissio0.69106811
128MP0003879_abnormal_hair_cell0.68482151
129MP0002116_abnormal_craniofacial_bone0.68409043
130MP0002063_abnormal_learning/memory/cond0.68003929
131MP0004142_abnormal_muscle_tone0.67350036
132MP0002177_abnormal_outer_ear0.66758139
133MP0003937_abnormal_limbs/digits/tail_de0.66287356
134MP0002233_abnormal_nose_morphology0.66038873

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.06676601
2Abnormal ciliary motility (HP:0012262)7.70289014
3Dynein arm defect of respiratory motile cilia (HP:0012255)7.24249014
4Absent/shortened dynein arms (HP:0200106)7.24249014
5Rhinitis (HP:0012384)6.34883351
6Abnormal respiratory motile cilium morphology (HP:0005938)6.23425214
7Abnormal respiratory epithelium morphology (HP:0012253)6.23425214
8Chronic bronchitis (HP:0004469)4.68695212
9Pancreatic fibrosis (HP:0100732)4.65881210
10True hermaphroditism (HP:0010459)4.05478533
11Nephronophthisis (HP:0000090)4.02286062
12Molar tooth sign on MRI (HP:0002419)3.93360431
13Abnormality of midbrain morphology (HP:0002418)3.93360431
14Medial flaring of the eyebrow (HP:0010747)3.82295910
15Bronchiectasis (HP:0002110)3.80747880
16Chronic hepatic failure (HP:0100626)3.57245440
17Pancreatic cysts (HP:0001737)3.25352936
18Abnormality of the renal medulla (HP:0100957)3.22422640
19Postaxial foot polydactyly (HP:0001830)3.11937240
20Nasal polyposis (HP:0100582)3.05168874
21Tubulointerstitial nephritis (HP:0001970)3.02436177
22Recurrent sinusitis (HP:0011108)2.98613948
23Congenital hepatic fibrosis (HP:0002612)2.97228220
24Median cleft lip (HP:0000161)2.93682124
25Congenital primary aphakia (HP:0007707)2.93564258
26Gait imbalance (HP:0002141)2.91269056
27Nephrogenic diabetes insipidus (HP:0009806)2.83290095
28Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82458336
29Bronchitis (HP:0012387)2.77942558
30Aplasia/Hypoplasia of the tongue (HP:0010295)2.75438003
31Infertility (HP:0000789)2.69482279
32Cystic liver disease (HP:0006706)2.62742236
33Occipital encephalocele (HP:0002085)2.60198715
34Preaxial hand polydactyly (HP:0001177)2.49960672
35Optic nerve hypoplasia (HP:0000609)2.49928804
36Chromsome breakage (HP:0040012)2.44168150
37Oligodactyly (hands) (HP:0001180)2.43961072
38Genital tract atresia (HP:0001827)2.39250050
39Bile duct proliferation (HP:0001408)2.37001179
40Abnormal biliary tract physiology (HP:0012439)2.37001179
41Abnormal spermatogenesis (HP:0008669)2.32295813
42Facial cleft (HP:0002006)2.30211889
43Postaxial hand polydactyly (HP:0001162)2.29450108
44Poor coordination (HP:0002370)2.28525080
45Abnormality of the nasal mucosa (HP:0000433)2.24062914
46Decreased central vision (HP:0007663)2.23230539
47Esophageal atresia (HP:0002032)2.22569340
48Aplasia/Hypoplasia of the lens (HP:0008063)2.22462108
49Vaginal atresia (HP:0000148)2.16616361
50Anophthalmia (HP:0000528)2.13675731
51Fibular hypoplasia (HP:0003038)2.10790355
52Chronic sinusitis (HP:0011109)2.10224340
53Male pseudohermaphroditism (HP:0000037)2.04867231
54Abnormality of the renal cortex (HP:0011035)2.03445953
55Duplicated collecting system (HP:0000081)2.03171180
56Supernumerary spleens (HP:0009799)2.01686880
57Furrowed tongue (HP:0000221)2.01056578
58Azoospermia (HP:0000027)2.01046402
59Anencephaly (HP:0002323)2.00031967
60Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.6662754
61Abnormal drinking behavior (HP:0030082)1.98189073
62Polydipsia (HP:0001959)1.98189073
63Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97826262
64Recurrent otitis media (HP:0000403)1.93889286
65Tubulointerstitial abnormality (HP:0001969)1.92031967
66Abnormality of molar morphology (HP:0011070)1.91496621
67Abnormality of molar (HP:0011077)1.91496621
68Metaphyseal dysplasia (HP:0100255)1.91058076
69Renal dysplasia (HP:0000110)1.90972803
70Abnormal hair whorl (HP:0010721)1.90815981
71Tubular atrophy (HP:0000092)1.90601278
72Abnormality of the renal collecting system (HP:0004742)1.90394942
73Aplasia/Hypoplasia of the spleen (HP:0010451)1.87717113
74Atonic seizures (HP:0010819)1.87299103
75Tongue fasciculations (HP:0001308)1.87185387
76Abnormality of the dental root (HP:0006486)1.85844374
77Taurodontia (HP:0000679)1.85844374
78Abnormality of permanent molar morphology (HP:0011071)1.85844374
79Nephropathy (HP:0000112)1.85394055
80Rib fusion (HP:0000902)1.85128410
81Chronic otitis media (HP:0000389)1.84569152
82Asplenia (HP:0001746)1.82445068
83Oligodactyly (HP:0012165)1.81232858
84Aplasia/Hypoplasia of the fibula (HP:0006492)1.80282822
85Male infertility (HP:0003251)1.77466611
86Sclerocornea (HP:0000647)1.72335194
87Aganglionic megacolon (HP:0002251)1.71933932
88Nephroblastoma (Wilms tumor) (HP:0002667)1.71500769
89Maternal diabetes (HP:0009800)1.70931725
90Astigmatism (HP:0000483)1.70015690
91Abnormality of the dental pulp (HP:0006479)1.69231123
92Stage 5 chronic kidney disease (HP:0003774)1.69182671
93Holoprosencephaly (HP:0001360)1.66444883
94Aplasia/Hypoplasia of the tibia (HP:0005772)1.66091104
95Abnormality of incisor morphology (HP:0011063)1.64771430
96Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.64331717
97Abnormality of lateral ventricle (HP:0030047)1.64014401
98Congenital, generalized hypertrichosis (HP:0004540)1.63858714
99Polyuria (HP:0000103)1.63356731
100Abnormal rod and cone electroretinograms (HP:0008323)1.63138433
101Atelectasis (HP:0100750)1.62708829
102Gastrointestinal atresia (HP:0002589)1.62268547
103Absent rod-and cone-mediated responses on ERG (HP:0007688)1.61386685
104White forelock (HP:0002211)1.59285681
105Embryonal renal neoplasm (HP:0011794)1.58836256
106Febrile seizures (HP:0002373)1.57833698
107Oculomotor apraxia (HP:0000657)1.56685404
108Broad distal phalanx of finger (HP:0009836)1.54012600
109Short tibia (HP:0005736)1.53591059
110Specific learning disability (HP:0001328)1.53409722
111Microglossia (HP:0000171)1.51994829
112Narrow forehead (HP:0000341)1.51386232
113Duplication of thumb phalanx (HP:0009942)1.51206003
114Retrobulbar optic neuritis (HP:0100654)1.51013782
115Optic neuritis (HP:0100653)1.51013782
116Patchy hypopigmentation of hair (HP:0011365)1.50864312
117Recurrent bronchitis (HP:0002837)1.50774122
118Septo-optic dysplasia (HP:0100842)1.48999850
119Multicystic kidney dysplasia (HP:0000003)1.48118592
120Absent septum pellucidum (HP:0001331)1.46700213
121Dyschromatopsia (HP:0007641)1.46100525
122Abnormality of renal resorption (HP:0011038)1.46018870
123Prominent nasal bridge (HP:0000426)1.45229516
124Bifid scrotum (HP:0000048)1.44632893
125Hyperactive renin-angiotensin system (HP:0000841)1.43194854
126Abdominal situs inversus (HP:0003363)1.42785774
127Abnormality of abdominal situs (HP:0011620)1.42785774
128Dyskinesia (HP:0100660)1.41183325
129Congenital stationary night blindness (HP:0007642)1.39028875
130Broad foot (HP:0001769)1.38949255
131Retinitis pigmentosa (HP:0000510)1.38420773
132Concave nail (HP:0001598)1.37962703
133Focal motor seizures (HP:0011153)1.37416258
134Bony spicule pigmentary retinopathy (HP:0007737)1.36212782
135Morphological abnormality of the inner ear (HP:0011390)1.32747912
136Abnormal urine output (HP:0012590)1.32271074
137Abnormality of renal excretion (HP:0011036)1.27203180

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK195.87432128
2CASK3.88315375
3MAP2K72.79570467
4STK162.76630032
5TNIK2.71767281
6PDK42.58677468
7PDK32.58677468
8MAP4K22.45601661
9MAPK152.36988320
10PNCK2.26018885
11MUSK2.19110918
12EPHB22.14430153
13SRPK12.13641912
14ADRBK22.02526585
15ZAK2.01127029
16BMPR21.98844074
17PDK21.89421021
18TSSK61.87450975
19GRK11.81748193
20TXK1.77710249
21SIK31.68494353
22STK38L1.66975892
23IRAK41.59255005
24AKT31.50153319
25INSRR1.49733561
26CCNB11.49007217
27YES11.48363970
28CDK31.43610149
29MKNK21.42997889
30MAPK131.36369862
31NEK61.36282781
32PLK41.34982372
33NME11.34563644
34VRK11.34530222
35IRAK11.21809550
36PRPF4B1.21380977
37ERBB31.21113219
38TLK11.17491943
39BMPR1B1.17177130
40IRAK31.15957315
41PTK2B1.15387637
42EIF2AK21.12548747
43MAP3K141.11980376
44WNK41.11132648
45TEC1.07553770
46EPHA31.06593441
47CAMKK21.06564910
48IRAK21.05579250
49SGK21.03946431
50DYRK31.03852513
51STK391.02429524
52CDC70.93515262
53NUAK10.91390762
54FRK0.88324678
55MKNK10.86645904
56STK240.81427790
57MARK20.78941635
58WEE10.78921620
59MAP3K120.78121167
60BRSK10.76124184
61CHEK20.75144677
62NTRK30.74668594
63ATR0.73772349
64PRKCE0.73759394
65CAMK1G0.73214957
66BCR0.72910943
67NTRK20.72789227
68BRD40.71749056
69BRSK20.71042918
70PKN10.69461572
71LMTK20.69278862
72GRK70.69244487
73EPHA40.67821594
74PLK10.67704911
75TTK0.65741660
76PRKCG0.65332105
77BRAF0.64666911
78TNK20.63198756
79PRKCI0.62957630
80MINK10.62523792
81FGFR20.61302409
82PRKD30.61284255
83EPHB10.60974819
84MARK10.60196716
85PASK0.58222709
86DYRK1B0.57908034
87DMPK0.56978821
88ACVR1B0.56600210
89PLK20.56054898
90SGK2230.55979999
91SGK4940.55979999
92DYRK20.54747562
93BTK0.54738029
94OXSR10.53755648
95MAP3K40.53721875
96CLK10.53388545
97MAP2K40.52311321
98CAMK10.52134542
99TIE10.51430947
100EPHA20.50034343
101AURKA0.49948646
102DYRK1A0.48937647
103UHMK10.48457685
104CDK80.48224910
105PRKG10.48095803
106PAK30.47110736
107NLK0.46990237
108ERBB20.46879746
109CAMKK10.45798165
110RPS6KA50.45036955
111RPS6KB10.44627343
112PINK10.44381854
113LYN0.44222338
114MST40.44183038
115MET0.43899333
116ATM0.43662567
117PRKCQ0.42343786
118MAPKAPK50.41391652
119BLK0.41162191
120PLK30.41080899
121CAMK2A0.40124466
122TYRO30.40001499
123SYK0.39609527
124RIPK40.38733446
125CAMK1D0.35872300
126ADRBK10.35804907
127MARK30.34922729
128MAPKAPK30.34643811
129MAP2K20.34321358
130ROCK10.33380019
131SGK10.33085330
132STK110.32475184
133PBK0.31980090
134PIK3CA0.31664134
135LRRK20.31507493
136PRKACA0.31334926
137WNK30.29826382
138TAOK30.28892722
139CSNK1A10.26895539
140TGFBR10.26199516
141VRK20.25968565
142MAP3K70.25807719

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.20096138
2Basal transcription factors_Homo sapiens_hsa030222.95371730
3Phototransduction_Homo sapiens_hsa047442.56614725
4Homologous recombination_Homo sapiens_hsa034402.42752215
5Parkinsons disease_Homo sapiens_hsa050122.37862377
6Ribosome_Homo sapiens_hsa030102.34754064
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.33316331
8Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.33238079
9Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.20825639
10Nicotine addiction_Homo sapiens_hsa050332.15660622
11Protein export_Homo sapiens_hsa030602.15427220
12Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.09555964
13Taste transduction_Homo sapiens_hsa047422.06299416
14Chemical carcinogenesis_Homo sapiens_hsa052042.06210903
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.87888894
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.80109567
17Huntingtons disease_Homo sapiens_hsa050161.66399230
18SNARE interactions in vesicular transport_Homo sapiens_hsa041301.65144884
19Ether lipid metabolism_Homo sapiens_hsa005651.65114881
20Sphingolipid metabolism_Homo sapiens_hsa006001.64781027
21Linoleic acid metabolism_Homo sapiens_hsa005911.61883960
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.53513057
23Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.47940194
24Steroid biosynthesis_Homo sapiens_hsa001001.45750100
25Graft-versus-host disease_Homo sapiens_hsa053321.45373525
26Purine metabolism_Homo sapiens_hsa002301.40751420
27Vitamin B6 metabolism_Homo sapiens_hsa007501.39651809
28Autoimmune thyroid disease_Homo sapiens_hsa053201.39449806
29Arachidonic acid metabolism_Homo sapiens_hsa005901.38913031
30Non-homologous end-joining_Homo sapiens_hsa034501.38833625
31Morphine addiction_Homo sapiens_hsa050321.36162987
32Olfactory transduction_Homo sapiens_hsa047401.34206690
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32398152
34Phenylalanine metabolism_Homo sapiens_hsa003601.31773043
35Allograft rejection_Homo sapiens_hsa053301.30333221
36Butanoate metabolism_Homo sapiens_hsa006501.28600824
37Nitrogen metabolism_Homo sapiens_hsa009101.28533304
38Caffeine metabolism_Homo sapiens_hsa002321.28464521
39Peroxisome_Homo sapiens_hsa041461.28315075
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27370114
41Retinol metabolism_Homo sapiens_hsa008301.27056366
42Rheumatoid arthritis_Homo sapiens_hsa053231.26696864
43Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.25298809
44beta-Alanine metabolism_Homo sapiens_hsa004101.24389345
45Histidine metabolism_Homo sapiens_hsa003401.22650370
46Serotonergic synapse_Homo sapiens_hsa047261.21319335
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.20846307
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.18070690
49Type I diabetes mellitus_Homo sapiens_hsa049401.15612672
50Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.15134995
51RNA polymerase_Homo sapiens_hsa030201.13196295
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.12313229
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.11839230
54Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.10997153
55ABC transporters_Homo sapiens_hsa020101.09613366
56Primary bile acid biosynthesis_Homo sapiens_hsa001201.05856365
57Tyrosine metabolism_Homo sapiens_hsa003501.05022689
58Glycosaminoglycan degradation_Homo sapiens_hsa005311.04456347
59Nucleotide excision repair_Homo sapiens_hsa034201.04120529
60Intestinal immune network for IgA production_Homo sapiens_hsa046721.03776164
61Collecting duct acid secretion_Homo sapiens_hsa049661.03647894
62Glutamatergic synapse_Homo sapiens_hsa047241.02360079
63RNA degradation_Homo sapiens_hsa030181.01780655
64Amphetamine addiction_Homo sapiens_hsa050311.01295105
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.00504246
66Propanoate metabolism_Homo sapiens_hsa006400.99251775
67Pyrimidine metabolism_Homo sapiens_hsa002400.97745100
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97662324
69Tryptophan metabolism_Homo sapiens_hsa003800.96792028
70Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.95392373
71Calcium signaling pathway_Homo sapiens_hsa040200.94912789
72Oxidative phosphorylation_Homo sapiens_hsa001900.94540432
73Insulin secretion_Homo sapiens_hsa049110.93621908
74Renin-angiotensin system_Homo sapiens_hsa046140.92815196
75Axon guidance_Homo sapiens_hsa043600.90563737
76Primary immunodeficiency_Homo sapiens_hsa053400.89203606
77Hematopoietic cell lineage_Homo sapiens_hsa046400.84888184
78Hippo signaling pathway_Homo sapiens_hsa043900.84721475
79Notch signaling pathway_Homo sapiens_hsa043300.84554294
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.84137242
81Asthma_Homo sapiens_hsa053100.81776553
82Circadian entrainment_Homo sapiens_hsa047130.81764018
83Base excision repair_Homo sapiens_hsa034100.81605223
84Other glycan degradation_Homo sapiens_hsa005110.79588713
85mRNA surveillance pathway_Homo sapiens_hsa030150.78468608
86Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.76716473
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74174476
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.73307479
89Mismatch repair_Homo sapiens_hsa034300.72534300
90Alcoholism_Homo sapiens_hsa050340.71688213
91Spliceosome_Homo sapiens_hsa030400.70093078
92Measles_Homo sapiens_hsa051620.67780824
93TGF-beta signaling pathway_Homo sapiens_hsa043500.67663830
94Glutathione metabolism_Homo sapiens_hsa004800.67591193
95Cocaine addiction_Homo sapiens_hsa050300.66147916
96Circadian rhythm_Homo sapiens_hsa047100.65295777
97GABAergic synapse_Homo sapiens_hsa047270.65256098
98Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.65069126
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.65001777
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62773487
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62639096
102Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61700083
103Ovarian steroidogenesis_Homo sapiens_hsa049130.61692244
104Wnt signaling pathway_Homo sapiens_hsa043100.61549364
105Hedgehog signaling pathway_Homo sapiens_hsa043400.59430636
106African trypanosomiasis_Homo sapiens_hsa051430.58265009
107Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.56924680
108Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55118701
109Renin secretion_Homo sapiens_hsa049240.52635792
110Jak-STAT signaling pathway_Homo sapiens_hsa046300.51356852
111Vitamin digestion and absorption_Homo sapiens_hsa049770.51191315
112Glycerolipid metabolism_Homo sapiens_hsa005610.50967666
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.50630547
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49191602
115Phagosome_Homo sapiens_hsa041450.49049240
116Synaptic vesicle cycle_Homo sapiens_hsa047210.48405948
117Cell cycle_Homo sapiens_hsa041100.46950166
118Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46834684
119Melanogenesis_Homo sapiens_hsa049160.46662371
120Selenocompound metabolism_Homo sapiens_hsa004500.46209498
121cAMP signaling pathway_Homo sapiens_hsa040240.46100217
122Tight junction_Homo sapiens_hsa045300.45693071
123Herpes simplex infection_Homo sapiens_hsa051680.44884768
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44607703
125Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44350865
126Alzheimers disease_Homo sapiens_hsa050100.43970340
127Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43082457
128Regulation of autophagy_Homo sapiens_hsa041400.42995842
129Bile secretion_Homo sapiens_hsa049760.42858367
130Dopaminergic synapse_Homo sapiens_hsa047280.42679636
131Mineral absorption_Homo sapiens_hsa049780.42289001
132Inositol phosphate metabolism_Homo sapiens_hsa005620.42052123
133Oocyte meiosis_Homo sapiens_hsa041140.41956365
134Fat digestion and absorption_Homo sapiens_hsa049750.41821179
135Pentose phosphate pathway_Homo sapiens_hsa000300.40456107
136Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.39596537
137Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38898335
138Basal cell carcinoma_Homo sapiens_hsa052170.38326986
139Cholinergic synapse_Homo sapiens_hsa047250.36347807
140Vibrio cholerae infection_Homo sapiens_hsa051100.35548873
141Cardiac muscle contraction_Homo sapiens_hsa042600.35448546
142Steroid hormone biosynthesis_Homo sapiens_hsa001400.35191861
143Metabolic pathways_Homo sapiens_hsa011000.34604421
144Salivary secretion_Homo sapiens_hsa049700.31884656
145Fatty acid biosynthesis_Homo sapiens_hsa000610.31660478
146Ras signaling pathway_Homo sapiens_hsa040140.31159615
147Influenza A_Homo sapiens_hsa051640.27771997

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