CCDC175

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.97589864
2cell-cell recognition (GO:0009988)9.87947502
3acrosome reaction (GO:0007340)9.58059217
4binding of sperm to zona pellucida (GO:0007339)9.51370874
5motile cilium assembly (GO:0044458)8.99191820
6cilium movement (GO:0003341)8.70657087
7spermatid development (GO:0007286)8.23973210
8epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.16450420
9piRNA metabolic process (GO:0034587)7.94365869
10male meiosis (GO:0007140)7.78839927
11protein neddylation (GO:0045116)7.77231956
12single fertilization (GO:0007338)7.58903124
13regulation of cilium movement (GO:0003352)7.35601622
14sperm capacitation (GO:0048240)7.13597342
15synaptonemal complex organization (GO:0070193)6.85197297
16synaptonemal complex assembly (GO:0007130)6.69187731
17fertilization (GO:0009566)6.11419283
18spermatid nucleus differentiation (GO:0007289)5.76362061
19microtubule depolymerization (GO:0007019)5.67357983
20ventricular system development (GO:0021591)5.54348630
21DNA methylation involved in gamete generation (GO:0043046)5.23462296
22spermatogenesis (GO:0007283)5.20966760
23male gamete generation (GO:0048232)5.19028501
24cell recognition (GO:0008037)5.07982552
25calcium ion-dependent exocytosis (GO:0017156)5.03813572
26negative regulation of inclusion body assembly (GO:0090084)4.82716526
27cellular process involved in reproduction in multicellular organism (GO:0022412)4.82315500
28gamete generation (GO:0007276)4.80141101
29chromosome organization involved in meiosis (GO:0070192)4.80040356
30germ cell development (GO:0007281)4.67387358
31thrombin receptor signaling pathway (GO:0070493)4.65841668
32male meiosis I (GO:0007141)4.59676892
33platelet dense granule organization (GO:0060155)4.53212519
34meiotic nuclear division (GO:0007126)4.41986945
35regulation of microtubule-based movement (GO:0060632)4.35753447
36organic cation transport (GO:0015695)4.34695499
37negative regulation of response to food (GO:0032096)4.28716122
38negative regulation of appetite (GO:0032099)4.28716122
39microtubule severing (GO:0051013)4.26525833
40protein localization to cilium (GO:0061512)4.15043458
41regulation of inclusion body assembly (GO:0090083)4.05784152
42aggressive behavior (GO:0002118)4.04829881
43negative regulation of heart rate (GO:0010459)3.94980239
44intraciliary transport (GO:0042073)3.92350213
45monoubiquitinated protein deubiquitination (GO:0035520)3.90957830
46left/right pattern formation (GO:0060972)3.82681722
47multicellular organismal reproductive process (GO:0048609)3.76634205
48meiosis I (GO:0007127)3.69913173
49regulation of female receptivity (GO:0045924)3.65762130
50negative regulation of norepinephrine secretion (GO:0010700)3.61209451
51GTP biosynthetic process (GO:0006183)3.54883283
52protein polyglutamylation (GO:0018095)3.54505013
53centriole assembly (GO:0098534)3.54340597
54glycerol ether metabolic process (GO:0006662)3.50983050
55single strand break repair (GO:0000012)3.46998569
56dopamine transport (GO:0015872)3.45812001
57negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.42497735
58negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.42033754
59seminiferous tubule development (GO:0072520)3.41652282
60cilium morphogenesis (GO:0060271)3.41099878
61mitochondrial respiratory chain complex I assembly (GO:0032981)3.40968686
62NADH dehydrogenase complex assembly (GO:0010257)3.40968686
63mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.40968686
64protein complex biogenesis (GO:0070271)3.39853154
65centriole replication (GO:0007099)3.39083329
66cilium organization (GO:0044782)3.38545625
67behavioral response to nicotine (GO:0035095)3.37338247
68microtubule-based movement (GO:0007018)3.35988465
69microtubule polymerization or depolymerization (GO:0031109)3.31047716
70cilium assembly (GO:0042384)3.30587795
71nucleoside diphosphate phosphorylation (GO:0006165)3.27430672
72axoneme assembly (GO:0035082)3.27006454
73ether metabolic process (GO:0018904)3.26937605
74protein K11-linked deubiquitination (GO:0035871)3.24847092
75meiotic cell cycle (GO:0051321)3.22281668
76activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)3.19826383
77relaxation of smooth muscle (GO:0044557)3.18469415
78chaperone-mediated protein complex assembly (GO:0051131)3.15858427
79rRNA modification (GO:0000154)3.15143458
80cellular component assembly involved in morphogenesis (GO:0010927)3.14049355
81rRNA methylation (GO:0031167)3.13914174
82synapsis (GO:0007129)3.08973861
83parturition (GO:0007567)3.08674969
84lactate metabolic process (GO:0006089)3.08192972
85genitalia morphogenesis (GO:0035112)3.07040321
86UTP biosynthetic process (GO:0006228)3.04901677
87mitochondrial respiratory chain complex assembly (GO:0033108)3.01471649
88female mating behavior (GO:0060180)3.01213592
89multicellular organismal development (GO:0007275)3.00822882
90negative regulation of neurotransmitter transport (GO:0051589)3.00414207
91mannosylation (GO:0097502)2.99703777
92gene silencing by RNA (GO:0031047)2.99144880
93preassembly of GPI anchor in ER membrane (GO:0016254)2.98591123
94sleep (GO:0030431)2.98455865
95mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.96874453
96alditol metabolic process (GO:0019400)2.93451583
97cellular ketone body metabolic process (GO:0046950)2.90811787
98negative regulation of organelle assembly (GO:1902116)2.89438726
99mitochondrial calcium ion transport (GO:0006851)2.87626665
100adaptation of signaling pathway (GO:0023058)2.87350310
101blood coagulation, intrinsic pathway (GO:0007597)2.87131937
102polyol catabolic process (GO:0046174)2.86193280
103positive regulation of cAMP-mediated signaling (GO:0043950)2.83024927
104regulation of hexokinase activity (GO:1903299)2.82746099
105regulation of glucokinase activity (GO:0033131)2.82746099
106regulation of centriole replication (GO:0046599)2.82526980
107protein-cofactor linkage (GO:0018065)2.82298690
108negative regulation of catecholamine secretion (GO:0033604)2.80854766
109negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.80569230
110phosphatidylinositol acyl-chain remodeling (GO:0036149)2.80494033
111DNA deamination (GO:0045006)2.78537255
112glycerol metabolic process (GO:0006071)2.77569020
113behavioral response to ethanol (GO:0048149)2.76132631
114pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.75393767
115meiotic cell cycle process (GO:1903046)2.71294264
116nitric oxide mediated signal transduction (GO:0007263)2.71140857
117regulation of response to food (GO:0032095)2.69590133
118respiratory chain complex IV assembly (GO:0008535)2.68385880
119UTP metabolic process (GO:0046051)2.68061385
120purinergic nucleotide receptor signaling pathway (GO:0035590)2.65959902
121water-soluble vitamin biosynthetic process (GO:0042364)2.65249380
122positive regulation of steroid hormone secretion (GO:2000833)2.65222454
123left/right axis specification (GO:0070986)2.65018154
124amine catabolic process (GO:0009310)2.64858231
125cellular biogenic amine catabolic process (GO:0042402)2.64858231
126neutrophil activation involved in immune response (GO:0002283)2.63028768
127photoreceptor cell maintenance (GO:0045494)2.62059339
128mitochondrial calcium ion homeostasis (GO:0051560)2.61960767
129monoamine transport (GO:0015844)2.61288276
130regulation of meiosis I (GO:0060631)2.61183900
131regulation of appetite (GO:0032098)2.60690516
132regulation of platelet activation (GO:0010543)2.58905921
133ether lipid metabolic process (GO:0046485)2.58375426
134regulation of spindle checkpoint (GO:0090231)2.58292495
135positive regulation of endothelial cell differentiation (GO:0045603)2.57698083
136guanosine-containing compound biosynthetic process (GO:1901070)2.56169948
137ATP synthesis coupled proton transport (GO:0015986)2.53854650
138energy coupled proton transport, down electrochemical gradient (GO:0015985)2.53854650
139positive regulation of mitochondrial fission (GO:0090141)2.51918140
140ketone body metabolic process (GO:1902224)2.51701167
141regulation of norepinephrine secretion (GO:0014061)2.51498941
142regulation of lipoprotein metabolic process (GO:0050746)2.51326668
143nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.51297369
144regulation of rhodopsin mediated signaling pathway (GO:0022400)2.50697340
145exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.50348203
146sexual reproduction (GO:0019953)2.50219563
147adenosine metabolic process (GO:0046085)2.49356348
148maternal behavior (GO:0042711)2.47940339
149detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.46234011
150nucleus organization (GO:0006997)2.45381248
151GPI anchor metabolic process (GO:0006505)2.44607757
152membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.44254164
153protein refolding (GO:0042026)2.42983896
154calcium ion import (GO:0070509)2.42718965
155glycerophospholipid catabolic process (GO:0046475)2.42706982
156mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.42545635
157DNA double-strand break processing (GO:0000729)2.41528331
158parental behavior (GO:0060746)2.40127236
159nonmotile primary cilium assembly (GO:0035058)2.39815979
160pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.39713865
161regulation of sensory perception of pain (GO:0051930)2.39462790
162regulation of sensory perception (GO:0051931)2.39462790
163phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.39225175
164regulation of penile erection (GO:0060405)2.38692084
165glycolytic process (GO:0006096)2.35523982
166single-organism membrane fusion (GO:0044801)2.35497969
167regulation of cytokine production involved in inflammatory response (GO:1900015)2.31505584
168amino-acid betaine transport (GO:0015838)2.30527475
169carnitine transport (GO:0015879)2.30527475
170CTP metabolic process (GO:0046036)2.27911685
171fusion of sperm to egg plasma membrane (GO:0007342)14.5219662
172cilium or flagellum-dependent cell motility (GO:0001539)14.0204141
173cell wall macromolecule metabolic process (GO:0044036)13.9971936
174cell wall macromolecule catabolic process (GO:0016998)13.9971936
175multicellular organism reproduction (GO:0032504)12.2288349
176acrosome assembly (GO:0001675)11.8974606
177sperm motility (GO:0030317)11.2840346
178plasma membrane fusion (GO:0045026)11.1637943
179sperm-egg recognition (GO:0035036)11.0818665
180epithelial cilium movement (GO:0003351)10.1598421
181reproduction (GO:0000003)10.0673595

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.44999022
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.84790223
3EZH2_22144423_ChIP-Seq_EOC_Human4.63035143
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.62378925
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.58165625
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.13720540
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.93867832
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.67479721
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.63771253
10CBX2_27304074_Chip-Seq_ESCs_Mouse2.58104674
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.45566500
12VDR_22108803_ChIP-Seq_LS180_Human2.40038327
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.36187366
14ZFP57_27257070_Chip-Seq_ESCs_Mouse2.32571912
15PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.28776706
16IGF1R_20145208_ChIP-Seq_DFB_Human2.20334016
17EWS_26573619_Chip-Seq_HEK293_Human2.19039088
18IRF1_19129219_ChIP-ChIP_H3396_Human2.17212446
19LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.05867975
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.01168767
21RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.99007628
22KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.98068139
23ZNF274_21170338_ChIP-Seq_K562_Hela1.94488883
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.90773480
25TAF15_26573619_Chip-Seq_HEK293_Human1.84671805
26SCL_19346495_ChIP-Seq_HPC-7_Human1.83246324
27KAP1_22055183_ChIP-Seq_ESCs_Mouse1.80049719
28EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.77802119
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.77736448
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.77331039
31TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.75235459
32TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.73943517
33TAL1_26923725_Chip-Seq_HPCs_Mouse1.72998062
34SUZ12_27294783_Chip-Seq_NPCs_Mouse1.72077925
35KDM2B_26808549_Chip-Seq_REH_Human1.71518655
36STAT6_21828071_ChIP-Seq_BEAS2B_Human1.71222663
37HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.68501249
38NFE2_27457419_Chip-Seq_LIVER_Mouse1.68366479
39RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65638286
40EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.62000818
41TP53_22573176_ChIP-Seq_HFKS_Human1.59697235
42SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.59263598
43NANOG_18555785_Chip-Seq_ESCs_Mouse1.58512945
44RNF2_27304074_Chip-Seq_NSC_Mouse1.57450092
45CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.56654415
46AR_25329375_ChIP-Seq_VCAP_Human1.53713599
47REST_21632747_ChIP-Seq_MESCs_Mouse1.52045023
48BCAT_22108803_ChIP-Seq_LS180_Human1.51780198
49CMYC_18555785_Chip-Seq_ESCs_Mouse1.48109696
50GATA1_26923725_Chip-Seq_HPCs_Mouse1.46796462
51MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45756144
52P53_22387025_ChIP-Seq_ESCs_Mouse1.45672953
53GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.45663484
54SOX2_19829295_ChIP-Seq_ESCs_Human1.45340989
55NANOG_19829295_ChIP-Seq_ESCs_Human1.45340989
56EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.43438914
57P300_18555785_Chip-Seq_ESCs_Mouse1.42745989
58STAT1_17558387_ChIP-Seq_HELA_Human1.42584697
59FLI1_21867929_ChIP-Seq_TH2_Mouse1.42254236
60HTT_18923047_ChIP-ChIP_STHdh_Human1.41748512
61GATA3_21878914_ChIP-Seq_MCF-7_Human1.41744690
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.41653627
63CRX_20693478_ChIP-Seq_RETINA_Mouse1.41399143
64OCT4_18555785_Chip-Seq_ESCs_Mouse1.41352920
65MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.41160181
66SUZ12_18555785_Chip-Seq_ESCs_Mouse1.39162203
67FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38472818
68FOXA1_25329375_ChIP-Seq_VCAP_Human1.38472818
69ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.37823893
70ELK4_26923725_Chip-Seq_MESODERM_Mouse1.37714283
71KLF4_18555785_Chip-Seq_ESCs_Mouse1.37535715
72MYC_18940864_ChIP-ChIP_HL60_Human1.37248400
73TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37089179
74CBP_20019798_ChIP-Seq_JUKART_Human1.36533350
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36533350
76FUS_26573619_Chip-Seq_HEK293_Human1.33881134
77STAT3_18555785_Chip-Seq_ESCs_Mouse1.33477830
78AR_20517297_ChIP-Seq_VCAP_Human1.31080259
79WDR5_24793694_ChIP-Seq_LNCAP_Human1.31021766
80BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30914993
81PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29004489
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28179033
83SOX2_18555785_Chip-Seq_ESCs_Mouse1.27274992
84ESRRB_18555785_Chip-Seq_ESCs_Mouse1.26642034
85PIAS1_25552417_ChIP-Seq_VCAP_Human1.25450530
86SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25446177
87MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24616916
88CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.23820918
89TOP2B_26459242_ChIP-Seq_MCF-7_Human1.23751705
90RUNX1_27457419_Chip-Seq_LIVER_Mouse1.23492008
91EST1_17652178_ChIP-ChIP_JURKAT_Human1.22925639
92STAT3_23295773_ChIP-Seq_U87_Human1.22463950
93ER_23166858_ChIP-Seq_MCF-7_Human1.22380139
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.21648888
95OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20762350
96FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20722337
97NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.20220651
98CTCF_18555785_Chip-Seq_ESCs_Mouse1.19133300
99ERG_20517297_ChIP-Seq_VCAP_Human1.18993401
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17207159
101CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17041136
102GATA3_21867929_ChIP-Seq_CD8_Mouse1.16993044
103SMAD1_18555785_Chip-Seq_ESCs_Mouse1.16832042
104OCT4_21477851_ChIP-Seq_ESCs_Mouse1.16717058
105POU3F2_20337985_ChIP-ChIP_501MEL_Human1.15952554
106GATA3_21867929_ChIP-Seq_TH1_Mouse1.15483984
107ELF1_17652178_ChIP-ChIP_JURKAT_Human1.15369152
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14711091
109POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14711091
110NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14030477
111TCF4_22108803_ChIP-Seq_LS180_Human1.13573783
112NMYC_18555785_Chip-Seq_ESCs_Mouse1.13435115
113ZFX_18555785_Chip-Seq_ESCs_Mouse1.12967415
114PU1_27457419_Chip-Seq_LIVER_Mouse1.12452920
115MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11931134
116GABP_17652178_ChIP-ChIP_JURKAT_Human1.09994662
117ETV2_25802403_ChIP-Seq_MESCs_Mouse1.09239504
118SOX2_22085726_ChIP-Seq_NPCs_Mouse1.08923770
119SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08860670
120GBX2_23144817_ChIP-Seq_PC3_Human1.08527085
121TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08303818
122GF1_26923725_Chip-Seq_HPCs_Mouse1.07417377
123FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06611793
124SOX9_26525672_Chip-Seq_HEART_Mouse1.06043552
125KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.05559868
126LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.05382152
127RUNX1_26923725_Chip-Seq_HPCs_Mouse1.04614680
128CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03898726
129RUNX2_22187159_ChIP-Seq_PCA_Human1.03371333
130PRDM14_20953172_ChIP-Seq_ESCs_Human1.02476893
131UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02194806
132GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01776559
133NCOR_22424771_ChIP-Seq_293T_Human1.01771726
134NANOG_20526341_ChIP-Seq_ESCs_Human0.99117421
135JUN_21703547_ChIP-Seq_K562_Human0.99020911
136E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.98468129
137AUTS2_25519132_ChIP-Seq_293T-REX_Human0.97374947
138TCF4_23295773_ChIP-Seq_U87_Human0.97353868
139GF1B_26923725_Chip-Seq_HPCs_Mouse0.96750625
140ELK1_19687146_ChIP-ChIP_HELA_Human0.96695456
141SMAD4_21799915_ChIP-Seq_A2780_Human0.96189495
142EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95063048
143SMAD4_21741376_ChIP-Seq_EPCs_Human0.94738427
144LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94628451
145CDX2_22108803_ChIP-Seq_LS180_Human0.94197393
146AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.92097052
147FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91770135
148PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.91587125
149SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91498384
150SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.90474299
151P300_19829295_ChIP-Seq_ESCs_Human0.89567077
152SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.89469248
153P53_21459846_ChIP-Seq_SAOS-2_Human0.89274055
154SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88666270
155CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88446397

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.49774661
2MP0001929_abnormal_gametogenesis4.93152900
3MP0008877_abnormal_DNA_methylation4.67890117
4MP0005464_abnormal_platelet_physiology4.19155206
5MP0002653_abnormal_ependyma_morphology3.73688028
6MP0006292_abnormal_olfactory_placode3.37852206
7MP0002210_abnormal_sex_determination3.34083425
8MP0002161_abnormal_fertility/fecundity2.93669953
9MP0005646_abnormal_pituitary_gland2.92732272
10MP0001145_abnormal_male_reproductive2.83158670
11MP0005084_abnormal_gallbladder_morpholo2.56768252
12MP0000653_abnormal_sex_gland2.48311020
13MP0003787_abnormal_imprinting2.43382240
14MP0008004_abnormal_stomach_pH2.35312218
15MP0009046_muscle_twitch2.31021182
16MP0005623_abnormal_meninges_morphology2.25556924
17MP0003724_increased_susceptibility_to2.07215307
18MP0003880_abnormal_central_pattern2.06513942
19MP0000465_gastrointestinal_hemorrhage2.06400375
20MP0005410_abnormal_fertilization13.4107303
21MP0008789_abnormal_olfactory_epithelium1.88036145
22MP0003718_maternal_effect1.86224722
23MP0005551_abnormal_eye_electrophysiolog1.78821560
24MP0000230_abnormal_systemic_arterial1.73322425
25MP0004147_increased_porphyrin_level1.73264356
26MP0004142_abnormal_muscle_tone1.69597442
27MP0005394_taste/olfaction_phenotype1.61416675
28MP0005499_abnormal_olfactory_system1.61416675
29MP0002160_abnormal_reproductive_system1.61348086
30MP0004885_abnormal_endolymph1.59727692
31MP0004233_abnormal_muscle_weight1.59692708
32MP0002102_abnormal_ear_morphology1.59345628
33MP0008775_abnormal_heart_ventricle1.54787180
34MP0001984_abnormal_olfaction1.54230300
35MP0008058_abnormal_DNA_repair1.49457464
36MP0002282_abnormal_trachea_morphology1.46590919
37MP0005423_abnormal_somatic_nervous1.44501695
38MP0002733_abnormal_thermal_nociception1.41543024
39MP0000566_synostosis1.39994769
40MP0002132_abnormal_respiratory_system1.33392453
41MP0006036_abnormal_mitochondrial_physio1.28957498
42MP0006072_abnormal_retinal_apoptosis1.28765989
43MP0003011_delayed_dark_adaptation1.26583926
44MP0006276_abnormal_autonomic_nervous1.24967504
45MP0002876_abnormal_thyroid_physiology1.23372264
46MP0001485_abnormal_pinna_reflex1.21154321
47MP0003806_abnormal_nucleotide_metabolis1.20259281
48MP0005253_abnormal_eye_physiology1.20117522
49MP0005167_abnormal_blood-brain_barrier1.19857857
50MP0001970_abnormal_pain_threshold1.19423822
51MP0002928_abnormal_bile_duct1.15050536
52MP0003195_calcinosis1.14682923
53MP0001529_abnormal_vocalization1.13978093
54MP0003303_peritoneal_inflammation1.13935802
55MP0009697_abnormal_copulation1.09956762
56MP0004270_analgesia1.04088714
57MP0005670_abnormal_white_adipose1.01835157
58MP0005174_abnormal_tail_pigmentation1.00775455
59MP0002736_abnormal_nociception_after1.00746382
60MP0003122_maternal_imprinting0.97033675
61MP0004084_abnormal_cardiac_muscle0.96890675
62MP0001765_abnormal_ion_homeostasis0.96342557
63MP0005647_abnormal_sex_gland0.96040900
64MP0001919_abnormal_reproductive_system0.95535042
65MP0002234_abnormal_pharynx_morphology0.94641372
66MP0008995_early_reproductive_senescence0.94366894
67MP0003638_abnormal_response/metabolism_0.92986726
68MP0001968_abnormal_touch/_nociception0.92805432
69MP0008057_abnormal_DNA_replication0.91796011
70MP0002572_abnormal_emotion/affect_behav0.90660532
71MP0003121_genomic_imprinting0.87685911
72MP0009745_abnormal_behavioral_response0.87409773
73MP0003635_abnormal_synaptic_transmissio0.86016915
74MP0005389_reproductive_system_phenotype0.85109981
75MP0001663_abnormal_digestive_system0.84938735
76MP0003646_muscle_fatigue0.84465035
77MP0003950_abnormal_plasma_membrane0.83722630
78MP0002064_seizures0.83522688
79MP0010329_abnormal_lipoprotein_level0.83241500
80MP0008875_abnormal_xenobiotic_pharmacok0.83016519
81MP0004742_abnormal_vestibular_system0.82282079
82MP0004085_abnormal_heartbeat0.81731386
83MP0004130_abnormal_muscle_cell0.81088797
84MP0002837_dystrophic_cardiac_calcinosis0.80550655
85MP0004215_abnormal_myocardial_fiber0.80073266
86MP0001440_abnormal_grooming_behavior0.78561972
87MP0009379_abnormal_foot_pigmentation0.78083278
88MP0003828_pulmonary_edema0.77345826
89MP0002272_abnormal_nervous_system0.76217745
90MP0002822_catalepsy0.75397249
91MP0001851_eye_inflammation0.74277557
92MP0010386_abnormal_urinary_bladder0.73212697
93MP0000015_abnormal_ear_pigmentation0.73078990
94MP0005535_abnormal_body_temperature0.72749164
95MP0003879_abnormal_hair_cell0.72464738
96MP0000569_abnormal_digit_pigmentation0.71863846
97MP0002063_abnormal_learning/memory/cond0.71601838
98MP0002938_white_spotting0.71562436
99MP0002229_neurodegeneration0.70531189
100MP0002734_abnormal_mechanical_nocicepti0.70174119
101MP0009780_abnormal_chondrocyte_physiolo0.70140134
102MP0000778_abnormal_nervous_system0.69744190
103MP0010094_abnormal_chromosome_stability0.69494811
104MP0000343_altered_response_to0.68609888
105MP0002067_abnormal_sensory_capabilities0.68212115
106MP0005195_abnormal_posterior_eye0.67945037
107MP0002752_abnormal_somatic_nervous0.67026447
108MP0004134_abnormal_chest_morphology0.66773099
109MP0002557_abnormal_social/conspecific_i0.66728493
110MP0002638_abnormal_pupillary_reflex0.66173281
111MP0005391_vision/eye_phenotype0.65496293
112MP0001486_abnormal_startle_reflex0.63044138
113MP0003786_premature_aging0.61678287
114MP0001324_abnormal_eye_pigmentation0.60203043
115MP0002882_abnormal_neuron_morphology0.59957194
116MP0001905_abnormal_dopamine_level0.59927060
117MP0000955_abnormal_spinal_cord0.56816146
118MP0002152_abnormal_brain_morphology0.55764166
119MP0005645_abnormal_hypothalamus_physiol0.55278051
120MP0001963_abnormal_hearing_physiology0.55076233
121MP0004043_abnormal_pH_regulation0.52843908
122MP0005409_darkened_coat_color0.51587725
123MP0004145_abnormal_muscle_electrophysio0.50081486
124MP0004133_heterotaxia0.49793855
125MP0000358_abnormal_cell_content/0.49467754
126MP0003699_abnormal_female_reproductive0.48246520
127MP0004036_abnormal_muscle_relaxation0.47961119
128MP0000026_abnormal_inner_ear0.47571899
129MP0008569_lethality_at_weaning0.47015861
130MP0004811_abnormal_neuron_physiology0.46994637
131MP0003633_abnormal_nervous_system0.46049520
132MP0002184_abnormal_innervation0.45683666
133MP0003183_abnormal_peptide_metabolism0.45660203
134MP0003861_abnormal_nervous_system0.45393478
135MP0002735_abnormal_chemical_nociception0.45001355
136MP0002163_abnormal_gland_morphology0.44868631
137MP0005636_abnormal_mineral_homeostasis0.44222531
138MP0002066_abnormal_motor_capabilities/c0.42388918
139MP0001501_abnormal_sleep_pattern0.42253521
140MP0001986_abnormal_taste_sensitivity0.41798308
141MP0003329_amyloid_beta_deposits0.41409694
142MP0004859_abnormal_synaptic_plasticity0.40905188
143MP0008872_abnormal_physiological_respon0.40814463
144MP0000631_abnormal_neuroendocrine_gland0.40739119
145MP0001293_anophthalmia0.40702502
146MP0003634_abnormal_glial_cell0.39953001
147MP0001664_abnormal_digestion0.39104500
148MP0003631_nervous_system_phenotype0.38608230
149MP0000647_abnormal_sebaceous_gland0.38109974
150MP0001188_hyperpigmentation0.37944828

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.14440834
2Abnormal respiratory epithelium morphology (HP:0012253)8.69487402
3Abnormal respiratory motile cilium morphology (HP:0005938)8.69487402
4Abnormal ciliary motility (HP:0012262)7.86619975
5Rhinitis (HP:0012384)7.56928440
6Chronic bronchitis (HP:0004469)6.96045596
7Nasal polyposis (HP:0100582)5.51444736
8Infertility (HP:0000789)5.43491619
9Prolonged bleeding time (HP:0003010)5.01040869
10Abnormality of the nasal mucosa (HP:0000433)4.37718409
11Bronchiectasis (HP:0002110)4.35082657
12Nephronophthisis (HP:0000090)4.11847605
13Bronchitis (HP:0012387)4.11671745
14Medial flaring of the eyebrow (HP:0010747)4.00431979
15Increased mean platelet volume (HP:0011877)3.80890847
16Petechiae (HP:0000967)3.79540744
17Menorrhagia (HP:0000132)3.73344127
183-Methylglutaconic aciduria (HP:0003535)3.58276711
19Recurrent sinusitis (HP:0011108)3.45728946
20Abnormal platelet volume (HP:0011876)3.43765144
21Acute necrotizing encephalopathy (HP:0006965)3.42040236
22Recurrent otitis media (HP:0000403)3.14692943
23Gait imbalance (HP:0002141)3.13987171
24Abnormality of the renal medulla (HP:0100957)3.13003693
25Renal cortical cysts (HP:0000803)3.12411548
26Congenital primary aphakia (HP:0007707)3.10517705
27Renal Fanconi syndrome (HP:0001994)3.09764226
28Purpura (HP:0000979)3.07362940
29Lipid accumulation in hepatocytes (HP:0006561)3.06584185
30Progressive macrocephaly (HP:0004481)2.96880937
31Abnormal mitochondria in muscle tissue (HP:0008316)2.96804323
32Mitochondrial inheritance (HP:0001427)2.96523711
33Acute encephalopathy (HP:0006846)2.96366919
34Congenital stationary night blindness (HP:0007642)2.96274388
35Abnormality of midbrain morphology (HP:0002418)2.91156817
36Molar tooth sign on MRI (HP:0002419)2.91156817
37Abnormal spermatogenesis (HP:0008669)2.88715093
38Male infertility (HP:0003251)2.86471613
39Tubulointerstitial nephritis (HP:0001970)2.83356974
40Nephrogenic diabetes insipidus (HP:0009806)2.72427037
41Increased hepatocellular lipid droplets (HP:0006565)2.64215893
42Epistaxis (HP:0000421)2.63595802
43Hepatic necrosis (HP:0002605)2.58001213
44Increased CSF lactate (HP:0002490)2.52798816
45Exertional dyspnea (HP:0002875)2.40927830
46Abnormal rod and cone electroretinograms (HP:0008323)2.40436420
47Genital tract atresia (HP:0001827)2.40078009
48Dyschromatopsia (HP:0007641)2.38750043
49Asplenia (HP:0001746)2.38128529
50Abnormality of alanine metabolism (HP:0010916)2.36724582
51Hyperalaninemia (HP:0003348)2.36724582
52Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36724582
53Vaginal atresia (HP:0000148)2.35274147
54Azoospermia (HP:0000027)2.34791595
55Aplasia/Hypoplasia of the spleen (HP:0010451)2.34725383
56Poor coordination (HP:0002370)2.34379666
57Hepatocellular necrosis (HP:0001404)2.33160979
58Stomatitis (HP:0010280)2.31866899
59Hyperthyroidism (HP:0000836)2.24252718
60Gonadotropin excess (HP:0000837)2.22715634
61Recurrent bronchitis (HP:0002837)2.22089177
62Abolished electroretinogram (ERG) (HP:0000550)2.21479964
63Abnormal biliary tract physiology (HP:0012439)2.19376209
64Bile duct proliferation (HP:0001408)2.19376209
65Hyperlipoproteinemia (HP:0010980)2.18997625
66Thyroid-stimulating hormone excess (HP:0002925)2.18093260
67Generalized aminoaciduria (HP:0002909)2.18048197
68Glycosuria (HP:0003076)2.17068508
69Abnormality of urine glucose concentration (HP:0011016)2.17068508
70Cerebral edema (HP:0002181)2.15827175
71Decreased central vision (HP:0007663)2.14191766
72Febrile seizures (HP:0002373)2.13704435
73Postaxial foot polydactyly (HP:0001830)2.11678996
74Gingival bleeding (HP:0000225)2.10148278
75Polyuria (HP:0000103)2.08707459
76Tongue fasciculations (HP:0001308)2.08224823
77Pancreatic fibrosis (HP:0100732)2.07596992
78Aplasia/Hypoplasia of the lens (HP:0008063)2.06715292
79Abnormal platelet function (HP:0011869)2.01348734
80Impaired platelet aggregation (HP:0003540)2.01348734
81Tubulointerstitial abnormality (HP:0001969)2.00863332
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2330019
83Dynein arm defect of respiratory motile cilia (HP:0012255)12.2149882
84Absent/shortened dynein arms (HP:0200106)12.2149882
85Chronic sinusitis (HP:0011109)1.99609058
86Abnormal pupillary function (HP:0007686)1.99175608
87Microglossia (HP:0000171)1.96658570
88Impulsivity (HP:0100710)1.96289944
89Congenital, generalized hypertrichosis (HP:0004540)1.95486764
90Male pseudohermaphroditism (HP:0000037)1.94374408
91Abnormality of permanent molar morphology (HP:0011071)1.93744007
92Abnormality of the dental root (HP:0006486)1.93744007
93Taurodontia (HP:0000679)1.93744007
94Tubular atrophy (HP:0000092)1.93623530
95Postaxial hand polydactyly (HP:0001162)1.93498496
96Methylmalonic acidemia (HP:0002912)1.92723624
97Increased intramyocellular lipid droplets (HP:0012240)1.91440691
98Atonic seizures (HP:0010819)1.90167937
99Increased muscle lipid content (HP:0009058)1.90120702
100Fibular hypoplasia (HP:0003038)1.87072277
101Optic nerve hypoplasia (HP:0000609)1.86023619
102Aplasia/Hypoplasia of the tongue (HP:0010295)1.85617189
103Congenital hepatic fibrosis (HP:0002612)1.85363626
104Muscle fibrillation (HP:0010546)1.85160884
105Sclerocornea (HP:0000647)1.84462846
106Tinnitus (HP:0000360)1.84157231
107Enlarged kidneys (HP:0000105)1.82475195
108Polyphagia (HP:0002591)1.82197150
109Abnormality of molar (HP:0011077)1.82125352
110Abnormality of molar morphology (HP:0011070)1.82125352
111Aplasia/Hypoplasia of the fovea (HP:0008060)1.81840968
112Hypoplasia of the fovea (HP:0007750)1.81840968
113Amyotrophic lateral sclerosis (HP:0007354)1.79507697
114J-shaped sella turcica (HP:0002680)1.77922062
115Anencephaly (HP:0002323)1.77608307
116Pachygyria (HP:0001302)1.77584005
117Abnormal number of erythroid precursors (HP:0012131)1.77393055
118Hypomagnesemia (HP:0002917)1.77148580
119Optic disc pallor (HP:0000543)1.76899041
120Abnormality of the dental pulp (HP:0006479)1.74205261
121Supernumerary spleens (HP:0009799)1.73471994
122True hermaphroditism (HP:0010459)1.73052855
123Poikilocytosis (HP:0004447)1.71803327
124Hypoplasia of the capital femoral epiphysis (HP:0003090)1.71071484
125Abnormality of the lower motor neuron (HP:0002366)1.70563118
126Oculomotor apraxia (HP:0000657)1.68782145
127Lethargy (HP:0001254)1.68464943
128Stage 5 chronic kidney disease (HP:0003774)1.67941938
129Abnormality of cells of the erythroid lineage (HP:0012130)1.67516130
130Heterotopia (HP:0002282)1.64547754
131Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.61400692
132Short ribs (HP:0000773)1.61315535
133Abnormality of macular pigmentation (HP:0008002)1.54640624
134Median cleft lip (HP:0000161)1.53764761
135Abnormality of saccadic eye movements (HP:0000570)1.53373624
136Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.51381419
137Facial cleft (HP:0002006)1.51277465
138Cerebellar dysplasia (HP:0007033)1.49729260
139Abnormality of renal resorption (HP:0011038)1.49275102
140Retinitis pigmentosa (HP:0000510)1.47758262
141Renal dysplasia (HP:0000110)1.47702923
142Retinal dysplasia (HP:0007973)1.46880887
143Absent rod-and cone-mediated responses on ERG (HP:0007688)1.44756290
144Abnormality of ocular smooth pursuit (HP:0000617)1.40606983
145Specific learning disability (HP:0001328)1.39442586
146Astigmatism (HP:0000483)1.38163532
147Severe visual impairment (HP:0001141)1.38008763
148Abnormal drinking behavior (HP:0030082)1.37977641
149Polydipsia (HP:0001959)1.37977641
150Abnormality of the renal cortex (HP:0011035)1.37972807
151Pancreatic cysts (HP:0001737)1.37571847
152Cystic liver disease (HP:0006706)1.36901340
153Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.36686802
154Absent epiphyses (HP:0010577)1.36686802
155Attenuation of retinal blood vessels (HP:0007843)1.35315271
156Broad foot (HP:0001769)1.35286118
157Dental crowding (HP:0000678)1.34948763
158Sensory axonal neuropathy (HP:0003390)1.33996872
159Abnormality of renal excretion (HP:0011036)1.32643192
160Type II lissencephaly (HP:0007260)1.31946305
161Choroideremia (HP:0001139)1.31853879
162Spastic tetraparesis (HP:0001285)1.30926750
163Impaired proprioception (HP:0010831)1.30417099
164Preaxial hand polydactyly (HP:0001177)1.27741984
165Constricted visual fields (HP:0001133)1.26483400

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.97391470
2PDK38.97391470
3PDK25.86181515
4STK393.02477832
5TESK12.95945179
6FRK2.94392195
7TAOK32.92705603
8ADRBK22.82920564
9WNK42.78462625
10PNCK2.76861958
11PRKD32.53799972
12NUAK12.51768791
13MAP4K22.40729819
14MST42.22987876
15ZAK2.22286118
16TXK2.20603951
17PTK2B2.09316888
18ICK1.99274063
19TEC1.82255557
20DAPK21.55681980
21TIE11.53770977
22DYRK21.48528754
23MYLK1.40564105
24BTK1.22655651
25VRK11.22275926
26IRAK11.17382045
27BUB11.14077264
28PBK1.10897400
29ACVR1B1.07447155
30WNK11.07299184
31NEK21.07169459
32PHKG21.06985431
33PHKG11.06985431
34BMPR1B1.05145408
35CSNK1G21.03270287
36SYK1.00057971
37ADRBK10.98669408
38STK380.98123708
39IKBKB0.96533018
40PLK40.95706144
41LMTK20.95329139
42INSRR0.93890106
43MAP2K70.91815748
44CSNK1G30.91453423
45BCKDK0.90888079
46FLT30.90586156
47FES0.90128493
48GRK60.86771279
49MAPK150.85735363
50CASK0.85717803
51MAP3K40.81473948
52IRAK20.81471458
53PIK3CG0.81120938
54RPS6KA50.80641637
55CCNB10.79803977
56TYRO30.79663231
57CSNK1G10.79379057
58BMX0.78072559
59TTK0.78053266
60DYRK30.77828542
61WEE10.74668119
62PDK10.74589192
63ITK0.74558751
64PRKCE0.73471446
65TNK20.72881146
66CHEK20.67461547
67STK38L0.67345664
68MARK30.67245251
69MKNK10.67031314
70OXSR10.66268121
71KIT0.66106258
72NEK60.65594814
73CAMKK20.64347672
74MAPKAPK30.64014752
75VRK20.63271176
76CSF1R0.62148529
77MAPKAPK50.61946106
78MUSK0.59572146
79MAP2K20.56808210
80DYRK1B0.55175057
81CDC70.52268967
82BRAF0.52248835
83SGK20.51693741
84PAK30.51473476
85PLK30.51090534
86CHEK10.48483089
87STK160.48177014
88LYN0.48145229
89SGK4940.46014917
90SGK2230.46014917
91PASK0.45974156
92PIK3CA0.45618531
93HIPK20.45017781
94CDK190.43222741
95PKN10.43205940
96EIF2AK10.42946880
97YES10.41617677
98NTRK20.40825804
99CAMK10.39743281
100PRKCA0.39422885
101PRKACG0.39047551
102STK240.38548694
103CSNK1A10.37596989
104RIPK40.37483576
105ARAF0.37182249
106TAF10.37120008
107CAMK1G0.37023551
108ATR0.36616078
109PRKCG0.36008167
110PLK10.35969492
111WNK30.35843962
112NME10.34882614
113ATM0.33822386
114EPHA40.33312503
115AKT30.33190519
116TLK10.30610777
117MINK10.30600041
118MARK10.30328154
119CAMK2A0.29484602
120BRSK20.29156580
121PLK20.28700421
122PRKCQ0.28456315
123STK30.28392703
124PAK10.26988640
125TESK20.26781555
126NTRK30.25401253
127CDK30.24947730
128CDK120.22948630
129CDK150.21834761
130GRK50.21675798
131PDPK10.21523814
132CDK180.21417911
133CDK140.20068895
134MAP2K40.19909789
135PRKG10.19854500
136PRKCZ0.19803026
137MAP2K60.18582217
138TNIK0.18178011
139CDK11A0.17819245
140GRK10.17521856
141CSNK2A20.17075425
142AURKA0.16750205
143PAK60.15856409
144CAMK2D0.15667724
145BCR0.15539600
146GRK70.15260173
147MAPK130.12914794
148CSNK1E0.12782805
149UHMK10.12229239
150CSNK2A10.12160598
151CDK50.11859608
152CDK10.11849986
153PRKACA0.10952511
154RPS6KB10.10952256
155PINK10.10538002
156MAPK100.10465398
157CAMK2B0.10161486
158CSNK1D0.09701897
159GSK3B0.08425924
160PRKG20.08355776

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.06089946
2Pyruvate metabolism_Homo sapiens_hsa006203.22401844
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.21546981
4Basal transcription factors_Homo sapiens_hsa030223.08183387
5Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.98064423
6Huntingtons disease_Homo sapiens_hsa050162.86758438
7Propanoate metabolism_Homo sapiens_hsa006402.37946655
8Phototransduction_Homo sapiens_hsa047442.35142919
9Nitrogen metabolism_Homo sapiens_hsa009102.31931986
10Platelet activation_Homo sapiens_hsa046112.31247518
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.30663962
12Pentose phosphate pathway_Homo sapiens_hsa000302.30323395
13Fanconi anemia pathway_Homo sapiens_hsa034602.21204872
14Ribosome_Homo sapiens_hsa030102.17547515
15Glucagon signaling pathway_Homo sapiens_hsa049222.16159265
16Linoleic acid metabolism_Homo sapiens_hsa005912.14394778
17Amphetamine addiction_Homo sapiens_hsa050312.07937529
18Oocyte meiosis_Homo sapiens_hsa041142.06942256
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.01528425
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.99466019
21Glycosaminoglycan degradation_Homo sapiens_hsa005311.95938794
22Cardiac muscle contraction_Homo sapiens_hsa042601.87266365
23Dorso-ventral axis formation_Homo sapiens_hsa043201.87048853
24Fatty acid biosynthesis_Homo sapiens_hsa000611.74330024
25Collecting duct acid secretion_Homo sapiens_hsa049661.71495148
26Oxidative phosphorylation_Homo sapiens_hsa001901.71470329
27Butanoate metabolism_Homo sapiens_hsa006501.65132063
28Synaptic vesicle cycle_Homo sapiens_hsa047211.63021358
29Ether lipid metabolism_Homo sapiens_hsa005651.61509926
30Renin secretion_Homo sapiens_hsa049241.50403905
31Maturity onset diabetes of the young_Homo sapiens_hsa049501.49701196
32Nicotine addiction_Homo sapiens_hsa050331.45216752
33Steroid hormone biosynthesis_Homo sapiens_hsa001401.43674368
34SNARE interactions in vesicular transport_Homo sapiens_hsa041301.43326061
35Purine metabolism_Homo sapiens_hsa002301.38436237
36Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.37992847
37Selenocompound metabolism_Homo sapiens_hsa004501.35529178
38Glycerolipid metabolism_Homo sapiens_hsa005611.33368862
39Taste transduction_Homo sapiens_hsa047421.32736330
40Regulation of autophagy_Homo sapiens_hsa041401.32631701
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.30860605
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.24776993
43Insulin secretion_Homo sapiens_hsa049111.22140296
44Long-term potentiation_Homo sapiens_hsa047201.21398227
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.21210090
46Parkinsons disease_Homo sapiens_hsa050121.20623741
47Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.19743895
48Alzheimers disease_Homo sapiens_hsa050101.17831420
49mRNA surveillance pathway_Homo sapiens_hsa030151.16033370
50Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.15985519
51Peroxisome_Homo sapiens_hsa041461.12715686
52Chemical carcinogenesis_Homo sapiens_hsa052041.11778564
53Carbohydrate digestion and absorption_Homo sapiens_hsa049731.11099359
54Glycerophospholipid metabolism_Homo sapiens_hsa005641.10623686
55Circadian entrainment_Homo sapiens_hsa047131.10236193
56Mineral absorption_Homo sapiens_hsa049781.08974331
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.07508707
58Retinol metabolism_Homo sapiens_hsa008301.06563709
59RNA transport_Homo sapiens_hsa030131.05502452
60Calcium signaling pathway_Homo sapiens_hsa040201.03244622
61Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.01894583
62Ovarian steroidogenesis_Homo sapiens_hsa049130.99195767
63Dopaminergic synapse_Homo sapiens_hsa047280.95592236
64Cocaine addiction_Homo sapiens_hsa050300.95496124
65Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.94919750
66Carbon metabolism_Homo sapiens_hsa012000.94193587
67Intestinal immune network for IgA production_Homo sapiens_hsa046720.94148436
68Tryptophan metabolism_Homo sapiens_hsa003800.92610367
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.92043441
70Asthma_Homo sapiens_hsa053100.90584839
71Homologous recombination_Homo sapiens_hsa034400.90299677
72Glutamatergic synapse_Homo sapiens_hsa047240.90266146
73Long-term depression_Homo sapiens_hsa047300.88750421
74Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.86638986
75Nucleotide excision repair_Homo sapiens_hsa034200.84147522
76Fructose and mannose metabolism_Homo sapiens_hsa000510.81412146
77Systemic lupus erythematosus_Homo sapiens_hsa053220.79348720
78Morphine addiction_Homo sapiens_hsa050320.79233020
79Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.78485586
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78427464
81Gap junction_Homo sapiens_hsa045400.78051274
82Vibrio cholerae infection_Homo sapiens_hsa051100.77848959
83Salivary secretion_Homo sapiens_hsa049700.76619632
84Hematopoietic cell lineage_Homo sapiens_hsa046400.76565877
85Mismatch repair_Homo sapiens_hsa034300.76431044
86Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.76073818
87RNA polymerase_Homo sapiens_hsa030200.74038430
88Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73914513
89Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72700140
90beta-Alanine metabolism_Homo sapiens_hsa004100.71473609
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.71268042
92Proteasome_Homo sapiens_hsa030500.67765020
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67155882
94Rheumatoid arthritis_Homo sapiens_hsa053230.65764473
95Inositol phosphate metabolism_Homo sapiens_hsa005620.65384503
96ABC transporters_Homo sapiens_hsa020100.65339652
97Olfactory transduction_Homo sapiens_hsa047400.65134372
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.64117020
99Type I diabetes mellitus_Homo sapiens_hsa049400.62729656
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62340026
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.62258417
102Metabolic pathways_Homo sapiens_hsa011000.61884744
103Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61185658
104Oxytocin signaling pathway_Homo sapiens_hsa049210.60835514
105Biosynthesis of amino acids_Homo sapiens_hsa012300.59426791
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59412259
107Caffeine metabolism_Homo sapiens_hsa002320.58235356
108Renin-angiotensin system_Homo sapiens_hsa046140.58002506
109RNA degradation_Homo sapiens_hsa030180.57561178
110cGMP-PKG signaling pathway_Homo sapiens_hsa040220.55274573
111Protein export_Homo sapiens_hsa030600.55223310
112One carbon pool by folate_Homo sapiens_hsa006700.55154404
113Pancreatic secretion_Homo sapiens_hsa049720.55008030
114N-Glycan biosynthesis_Homo sapiens_hsa005100.54487290
115PPAR signaling pathway_Homo sapiens_hsa033200.54305266
116Gastric acid secretion_Homo sapiens_hsa049710.53337152
117Estrogen signaling pathway_Homo sapiens_hsa049150.53048060
118Serotonergic synapse_Homo sapiens_hsa047260.52501638
119Thyroid hormone synthesis_Homo sapiens_hsa049180.52030981
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50492048
121cAMP signaling pathway_Homo sapiens_hsa040240.50417309
122GABAergic synapse_Homo sapiens_hsa047270.50405924
123Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49626418
124Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49421282
125Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.48287308
126Arachidonic acid metabolism_Homo sapiens_hsa005900.46926607
127Pyrimidine metabolism_Homo sapiens_hsa002400.46077802
128Hedgehog signaling pathway_Homo sapiens_hsa043400.44243540
129Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.43756803
130Sphingolipid metabolism_Homo sapiens_hsa006000.41793794
131Vascular smooth muscle contraction_Homo sapiens_hsa042700.38967961
132Glutathione metabolism_Homo sapiens_hsa004800.38134679
133Fatty acid elongation_Homo sapiens_hsa000620.37191007
134Fatty acid degradation_Homo sapiens_hsa000710.37106518
135Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36235870
136Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35905017
137Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35558356
138Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.33571561
139Sulfur metabolism_Homo sapiens_hsa009200.33324684
140Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32736646
141Alcoholism_Homo sapiens_hsa050340.31323264
142Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.31271394
143Aldosterone synthesis and secretion_Homo sapiens_hsa049250.30177379
144Fat digestion and absorption_Homo sapiens_hsa049750.28660417
145Spliceosome_Homo sapiens_hsa030400.27086427

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