CCDC24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fatty acid elongation (GO:0030497)7.20964968
2regulation of rhodopsin mediated signaling pathway (GO:0022400)7.12648093
3rhodopsin mediated signaling pathway (GO:0016056)7.00470597
4eye photoreceptor cell differentiation (GO:0001754)6.32680409
5photoreceptor cell differentiation (GO:0046530)6.32680409
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.30415706
7behavioral response to nicotine (GO:0035095)6.24421921
8photoreceptor cell maintenance (GO:0045494)5.49771946
9ensheathment of neurons (GO:0007272)5.27568355
10axon ensheathment (GO:0008366)5.27568355
11myelination (GO:0042552)5.25750910
12response to methylmercury (GO:0051597)5.13911143
13detection of light stimulus involved in sensory perception (GO:0050962)4.84141625
14detection of light stimulus involved in visual perception (GO:0050908)4.84141625
15motile cilium assembly (GO:0044458)4.82558077
16regulation of cilium movement (GO:0003352)4.71462105
17long-chain fatty acid biosynthetic process (GO:0042759)4.66698935
18retinal cone cell development (GO:0046549)4.42319119
19photoreceptor cell development (GO:0042461)4.08024795
20negative regulation of neurotransmitter transport (GO:0051589)3.96170478
21eye photoreceptor cell development (GO:0042462)3.94675983
22negative regulation of neurotransmitter secretion (GO:0046929)3.90913967
23establishment of mitochondrion localization (GO:0051654)3.86875626
24nonmotile primary cilium assembly (GO:0035058)3.77780484
25presynaptic membrane organization (GO:0097090)3.77074798
26oligodendrocyte differentiation (GO:0048709)3.76357354
27detection of visible light (GO:0009584)3.75647540
28phototransduction (GO:0007602)3.75163870
29phototransduction, visible light (GO:0007603)3.74958146
30respiratory chain complex IV assembly (GO:0008535)3.74846010
31protein localization to cilium (GO:0061512)3.74216536
32cellular response to ATP (GO:0071318)3.73170962
33detection of light stimulus (GO:0009583)3.72810069
34cholesterol biosynthetic process (GO:0006695)3.65937568
35GMP metabolic process (GO:0046037)3.62483491
36presynaptic membrane assembly (GO:0097105)3.60823856
37myelin maintenance (GO:0043217)3.57363781
38protein complex biogenesis (GO:0070271)3.56234151
39apical protein localization (GO:0045176)3.56014037
40cilium organization (GO:0044782)3.55633002
41water-soluble vitamin biosynthetic process (GO:0042364)3.51489292
42regulation of microtubule-based movement (GO:0060632)3.50922136
43L-fucose catabolic process (GO:0042355)3.50902834
44fucose catabolic process (GO:0019317)3.50902834
45L-fucose metabolic process (GO:0042354)3.50902834
46positive regulation of guanylate cyclase activity (GO:0031284)3.50549824
47visual perception (GO:0007601)3.46896927
48negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.46013699
49long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.45511272
50asymmetric protein localization (GO:0008105)3.45134967
51cilium assembly (GO:0042384)3.45096062
52sensory perception of light stimulus (GO:0050953)3.45088785
53import into cell (GO:0098657)3.43497087
54cytochrome complex assembly (GO:0017004)3.42915958
55short-term memory (GO:0007614)3.42107503
56glycerophospholipid catabolic process (GO:0046475)3.39653820
57left/right pattern formation (GO:0060972)3.38137346
58cilium morphogenesis (GO:0060271)3.36050166
59L-amino acid import (GO:0043092)3.32006194
60cornea development in camera-type eye (GO:0061303)3.31320100
61mitochondrial respiratory chain complex I assembly (GO:0032981)3.29614082
62NADH dehydrogenase complex assembly (GO:0010257)3.29614082
63mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.29614082
64negative regulation of execution phase of apoptosis (GO:1900118)3.29589497
65sterol biosynthetic process (GO:0016126)3.28999963
66intraciliary transport (GO:0042073)3.28619069
67mitochondrial respiratory chain complex assembly (GO:0033108)3.27107088
68negative regulation of telomere maintenance (GO:0032205)3.26703716
69negative regulation of protein localization to cell surface (GO:2000009)3.26494754
70retinal rod cell development (GO:0046548)3.24383849
71regulation of guanylate cyclase activity (GO:0031282)3.24092504
72regulation of collateral sprouting (GO:0048670)3.23670740
73long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.21439394
74GPI anchor biosynthetic process (GO:0006506)3.15215360
75amyloid precursor protein metabolic process (GO:0042982)3.13641039
76response to redox state (GO:0051775)3.09803599
77cellular ketone body metabolic process (GO:0046950)3.09406595
78regulation of lipoprotein metabolic process (GO:0050746)3.07514798
79GPI anchor metabolic process (GO:0006505)3.07477101
80ubiquinone biosynthetic process (GO:0006744)3.07062908
81vitamin transmembrane transport (GO:0035461)3.06772853
82energy coupled proton transport, down electrochemical gradient (GO:0015985)3.06575074
83ATP synthesis coupled proton transport (GO:0015986)3.06575074
84piRNA metabolic process (GO:0034587)3.05537587
85limb bud formation (GO:0060174)3.05116899
86retina layer formation (GO:0010842)3.04667164
87negative regulation of T cell differentiation in thymus (GO:0033085)3.03818699
88very long-chain fatty acid metabolic process (GO:0000038)3.00959482
89regulation of catecholamine metabolic process (GO:0042069)3.00093414
90regulation of dopamine metabolic process (GO:0042053)3.00093414
91nephron tubule morphogenesis (GO:0072078)2.99203301
92nephron epithelium morphogenesis (GO:0072088)2.99203301
93fatty-acyl-CoA biosynthetic process (GO:0046949)2.97708278
94response to pheromone (GO:0019236)2.97206576
95positive regulation of oligodendrocyte differentiation (GO:0048714)2.95177886
96detection of external stimulus (GO:0009581)2.93861828
97negative regulation of cell aging (GO:0090344)2.92253053
98detection of abiotic stimulus (GO:0009582)2.91306134
99acrosome reaction (GO:0007340)2.90832770
100regulation of nuclear cell cycle DNA replication (GO:0033262)2.89097714
101preassembly of GPI anchor in ER membrane (GO:0016254)2.88461499
102isoprenoid biosynthetic process (GO:0008299)2.85641996
103protein import into peroxisome matrix (GO:0016558)2.84789815
104protein-chromophore linkage (GO:0018298)2.83746837
105mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.83446307
106cerebral cortex radially oriented cell migration (GO:0021799)2.82937074
107microtubule bundle formation (GO:0001578)2.82225868
108axoneme assembly (GO:0035082)2.82196431
109ubiquinone metabolic process (GO:0006743)2.81529167
110fatty-acyl-CoA metabolic process (GO:0035337)2.81289572
111microtubule polymerization or depolymerization (GO:0031109)2.80534746
112retina development in camera-type eye (GO:0060041)2.79319241
113mannosylation (GO:0097502)2.79243779
114neurotransmitter uptake (GO:0001504)2.78809539
115epithelial cilium movement (GO:0003351)2.77249709
116spinal cord motor neuron differentiation (GO:0021522)2.76584921
117protein polyglutamylation (GO:0018095)2.76352284
118cilium or flagellum-dependent cell motility (GO:0001539)2.75316494
119positive regulation of cellular amine metabolic process (GO:0033240)2.75290629
120protein palmitoylation (GO:0018345)2.73600273
121mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.73128720
122astrocyte development (GO:0014002)2.72629612
123neuron remodeling (GO:0016322)2.71699428
124multicellular organism reproduction (GO:0032504)2.71202136
125ketone body metabolic process (GO:1902224)2.70521165
126positive regulation of action potential (GO:0045760)2.70140271
127response to lead ion (GO:0010288)2.70068328
128base-excision repair, AP site formation (GO:0006285)2.68009570
129synaptic transmission, cholinergic (GO:0007271)2.65194965
130indolalkylamine metabolic process (GO:0006586)2.64491702
131detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.64374734
132DNA methylation involved in gamete generation (GO:0043046)2.63909120
133kynurenine metabolic process (GO:0070189)2.62521257
134creatine metabolic process (GO:0006600)2.61694411
135cilium movement (GO:0003341)2.61685234
136amino acid import (GO:0043090)2.60806009
137left/right axis specification (GO:0070986)2.59168050
138rRNA modification (GO:0000154)2.58625440
139axonemal dynein complex assembly (GO:0070286)2.57956932
140rRNA methylation (GO:0031167)2.57642430
141substantia nigra development (GO:0021762)2.56734023
142electron transport chain (GO:0022900)2.55223091
143cellular component assembly involved in morphogenesis (GO:0010927)2.55067416
144negative regulation of inclusion body assembly (GO:0090084)2.55058018
145rRNA catabolic process (GO:0016075)2.52956559
146DNA deamination (GO:0045006)2.52668961
147estrogen biosynthetic process (GO:0006703)2.52399396
148heme transport (GO:0015886)2.51981336
149establishment of protein localization to mitochondrial membrane (GO:0090151)2.50275567
150peristalsis (GO:0030432)2.49914947
151regulation of cGMP metabolic process (GO:0030823)2.49336890
152axon development (GO:0061564)2.48743481
153enteric nervous system development (GO:0048484)2.48712966
154tryptophan catabolic process (GO:0006569)2.47822800
155indole-containing compound catabolic process (GO:0042436)2.47822800
156indolalkylamine catabolic process (GO:0046218)2.47822800
157cell morphogenesis involved in neuron differentiation (GO:0048667)2.46236506
158neuronal action potential (GO:0019228)2.44341355
159quinone biosynthetic process (GO:1901663)2.43499326
160iron coordination entity transport (GO:1901678)2.43435048
161nucleotide transmembrane transport (GO:1901679)2.42743339
162protoporphyrinogen IX metabolic process (GO:0046501)2.41640797
163positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.41349207
164reciprocal meiotic recombination (GO:0007131)2.41100020
165reciprocal DNA recombination (GO:0035825)2.41100020
166phosphatidylglycerol biosynthetic process (GO:0006655)2.40418558
167sperm motility (GO:0030317)2.40332344
168cranial nerve development (GO:0021545)2.39724498
169nucleoside diphosphate phosphorylation (GO:0006165)2.37882459
170neuromuscular synaptic transmission (GO:0007274)2.37577872
171respiratory electron transport chain (GO:0022904)2.37319341
172purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.36770219
1733-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.36770219
174neurotransmitter metabolic process (GO:0042133)2.36534537
175protein-cofactor linkage (GO:0018065)2.35533116
176regulation of synapse structural plasticity (GO:0051823)2.35478516
177regulation of action potential (GO:0098900)2.34716036
178smoothened signaling pathway (GO:0007224)2.33177104
179intracellular protein transmembrane import (GO:0044743)2.32639415
180determination of left/right symmetry (GO:0007368)2.30187332
181startle response (GO:0001964)2.30134044
182fucosylation (GO:0036065)2.29630226
183central nervous system myelination (GO:0022010)10.0011803
184axon ensheathment in central nervous system (GO:0032291)10.0011803

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.49223118
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.09266228
3GBX2_23144817_ChIP-Seq_PC3_Human3.01984941
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.94368758
5EZH2_22144423_ChIP-Seq_EOC_Human2.68274495
6CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.53597569
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.43216335
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.39420783
9NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.38344542
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.15584214
11SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.10852977
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08583803
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.08544661
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.03328132
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.01228646
16EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.00951845
17JARID2_20064375_ChIP-Seq_MESCs_Mouse2.00260136
18TAF15_26573619_Chip-Seq_HEK293_Human1.97981714
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.97488047
20VDR_22108803_ChIP-Seq_LS180_Human1.95460125
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.88435979
22SUZ12_27294783_Chip-Seq_ESCs_Mouse1.86640222
23SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.86186046
24EZH2_27294783_Chip-Seq_ESCs_Mouse1.85960177
25ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84356056
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.83384304
27MTF2_20144788_ChIP-Seq_MESCs_Mouse1.82092079
28GABP_17652178_ChIP-ChIP_JURKAT_Human1.81992003
29RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.80948196
30ERA_21632823_ChIP-Seq_H3396_Human1.76540850
31EWS_26573619_Chip-Seq_HEK293_Human1.75963036
32EZH2_18974828_ChIP-Seq_MESCs_Mouse1.75038807
33RNF2_18974828_ChIP-Seq_MESCs_Mouse1.75038807
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.74536947
35JARID2_20075857_ChIP-Seq_MESCs_Mouse1.70726392
36JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.69854963
37TP53_22573176_ChIP-Seq_HFKS_Human1.69446148
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.68992968
39* E2F1_20622854_ChIP-Seq_HELA_Human1.67614084
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.66456188
41* CTCF_27219007_Chip-Seq_Bcells_Human1.65486069
42AR_21572438_ChIP-Seq_LNCaP_Human1.65433243
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.62992114
44MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62399756
45EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.62091285
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.61633208
47OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.59881653
48TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59767435
49RNF2_27304074_Chip-Seq_ESCs_Mouse1.58988106
50PHF8_20622854_ChIP-Seq_HELA_Human1.57502180
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55019079
52ER_23166858_ChIP-Seq_MCF-7_Human1.54935271
53* P68_20966046_ChIP-Seq_HELA_Human1.52981636
54* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.51261721
55CTBP2_25329375_ChIP-Seq_LNCAP_Human1.48818089
56BCL6_27268052_Chip-Seq_Bcells_Human1.46973199
57MYC_19829295_ChIP-Seq_ESCs_Human1.46052085
58PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43270934
59SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.42980738
60GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.41657581
61NANOG_20526341_ChIP-Seq_ESCs_Human1.40904184
62REST_18959480_ChIP-ChIP_MESCs_Mouse1.40840637
63MYC_18940864_ChIP-ChIP_HL60_Human1.39653220
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39521610
65* TAF2_19829295_ChIP-Seq_ESCs_Human1.39161405
66SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.38827396
67FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38172218
68FOXA1_25329375_ChIP-Seq_VCAP_Human1.38172218
69SMAD3_21741376_ChIP-Seq_EPCs_Human1.37024827
70KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36322221
71P53_21459846_ChIP-Seq_SAOS-2_Human1.36100637
72OCT4_20526341_ChIP-Seq_ESCs_Human1.35226455
73GATA3_21878914_ChIP-Seq_MCF-7_Human1.35076719
74* CTCF_20526341_ChIP-Seq_ESCs_Human1.33922957
75FUS_26573619_Chip-Seq_HEK293_Human1.32611902
76P300_19829295_ChIP-Seq_ESCs_Human1.32544396
77TAL1_26923725_Chip-Seq_HPCs_Mouse1.32061352
78YY1_22570637_ChIP-Seq_MALME-3M_Human1.31890500
79EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.29822689
80TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29709952
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.28285462
82CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.28166997
83TDRD3_21172665_ChIP-Seq_MCF-7_Human1.27770201
84PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27692470
85NCOR_22424771_ChIP-Seq_293T_Human1.27370434
86NANOG_18555785_Chip-Seq_ESCs_Mouse1.27213489
87MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.26661410
88ETV2_25802403_ChIP-Seq_MESCs_Mouse1.24703212
89EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.23901813
90TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.22182460
91AR_20517297_ChIP-Seq_VCAP_Human1.20551252
92FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.19198797
93HOXB7_26014856_ChIP-Seq_BT474_Human1.18337135
94RNF2_27304074_Chip-Seq_NSC_Mouse1.18187671
95RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.18154380
96IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17454838
97BCOR_27268052_Chip-Seq_Bcells_Human1.17219514
98P300_27268052_Chip-Seq_Bcells_Human1.16584335
99IGF1R_20145208_ChIP-Seq_DFB_Human1.15921307
100SRF_21415370_ChIP-Seq_HL-1_Mouse1.15758121
101DROSHA_22980978_ChIP-Seq_HELA_Human1.15450512
102CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.14335742
103ETS1_20019798_ChIP-Seq_JURKAT_Human1.14120348
104VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.13881240
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13690260
106RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.13067928
107TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12906558
108MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.12891281
109ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.10734215
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10097554
111SUZ12_18555785_Chip-Seq_ESCs_Mouse1.09910352
112IRF1_19129219_ChIP-ChIP_H3396_Human1.09684732
113CMYC_18555785_Chip-Seq_ESCs_Mouse1.09529947
114* RARB_24833708_ChIP-Seq_LIVER_Mouse1.09312177
115EST1_17652178_ChIP-ChIP_JURKAT_Human1.09174197
116REST_21632747_ChIP-Seq_MESCs_Mouse1.08988589
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08120039
118GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06766112
119PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.06641962
120MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05613438
121P300_18555785_Chip-Seq_ESCs_Mouse1.04960330
122STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.04768227
123CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.04625279
124ELF1_20517297_ChIP-Seq_JURKAT_Human1.04618556
125SMAD4_21799915_ChIP-Seq_A2780_Human1.03691064
126TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03475965
127POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03475965
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03352034
129KDM2B_26808549_Chip-Seq_REH_Human1.03010297
130* FOXP1_21924763_ChIP-Seq_HESCs_Human1.02919316
131CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.02819293
132UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02508204
133* SOX2_21211035_ChIP-Seq_LN229_Human1.01978412
134PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01732438
135STAT3_23295773_ChIP-Seq_U87_Human1.01359324
136EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.01332541
137* LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00772198
138SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00139821
139* TBL1_22424771_ChIP-Seq_293T_Human1.00032919
140P53_22387025_ChIP-Seq_ESCs_Mouse0.99782726
141* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.98819191
142SALL1_21062744_ChIP-ChIP_HESCs_Human0.98720620
143RING1B_27294783_Chip-Seq_NPCs_Mouse0.98174415
144LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98171659
145TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97501142
146* SA1_27219007_Chip-Seq_Bcells_Human0.97405053
147P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97081183
148SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.96839698
149E2F1_18555785_Chip-Seq_ESCs_Mouse0.96607206
150GATA1_26923725_Chip-Seq_HPCs_Mouse0.96353982
151POU5F1_16153702_ChIP-ChIP_HESCs_Human0.95815562
152PRDM14_20953172_ChIP-Seq_ESCs_Human0.94892865
153RING1B_27294783_Chip-Seq_ESCs_Mouse0.94649086
154FLI1_27457419_Chip-Seq_LIVER_Mouse0.94583329
155ERG_21242973_ChIP-ChIP_JURKAT_Human0.94473965
156NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.93473098
157VDR_23849224_ChIP-Seq_CD4+_Human0.92695833
158FOXH1_21741376_ChIP-Seq_ESCs_Human0.92499641
159RAC3_21632823_ChIP-Seq_H3396_Human0.92446072
160SOX2_19829295_ChIP-Seq_ESCs_Human0.92204058
161NANOG_19829295_ChIP-Seq_ESCs_Human0.92204058
162CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.92066586
163NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91706283
164PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91692413
165SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.91656163
166STAT3_18555785_Chip-Seq_ESCs_Mouse0.91382690
167SOX2_18555785_Chip-Seq_ESCs_Mouse0.91003070
168RUNX1_27457419_Chip-Seq_LIVER_Mouse0.90751430
169ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.89062969
170KLF4_18555785_Chip-Seq_ESCs_Mouse0.88995981

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005551_abnormal_eye_electrophysiolog5.23232820
2MP0003011_delayed_dark_adaptation4.95556508
3MP0003950_abnormal_plasma_membrane4.46712651
4MP0008875_abnormal_xenobiotic_pharmacok3.65206117
5MP0003136_yellow_coat_color3.57225061
6MP0006072_abnormal_retinal_apoptosis3.55865742
7MP0005253_abnormal_eye_physiology3.50033799
8MP0000920_abnormal_myelination3.33672341
9MP0005410_abnormal_fertilization3.07071686
10MP0005423_abnormal_somatic_nervous2.82777602
11MP0003880_abnormal_central_pattern2.78001411
12MP0004270_analgesia2.52711096
13MP0005195_abnormal_posterior_eye2.46539815
14MP0004133_heterotaxia2.40523318
15MP0002229_neurodegeneration2.30653525
16MP0004885_abnormal_endolymph2.26367823
17MP0005174_abnormal_tail_pigmentation2.11287701
18MP0008877_abnormal_DNA_methylation2.10733755
19MP0004742_abnormal_vestibular_system2.09644425
20MP0005377_hearing/vestibular/ear_phenot2.02558962
21MP0003878_abnormal_ear_physiology2.02558962
22MP0004381_abnormal_hair_follicle2.00160068
23MP0001486_abnormal_startle_reflex1.91228595
24MP0002272_abnormal_nervous_system1.90523393
25MP0001905_abnormal_dopamine_level1.88252684
26MP0005171_absent_coat_pigmentation1.85096583
27MP0003634_abnormal_glial_cell1.81198435
28MP0005391_vision/eye_phenotype1.79943570
29MP0002638_abnormal_pupillary_reflex1.72466504
30MP0002752_abnormal_somatic_nervous1.70247794
31MP0004043_abnormal_pH_regulation1.69113091
32MP0001529_abnormal_vocalization1.68396333
33MP0002653_abnormal_ependyma_morphology1.67564770
34MP0003690_abnormal_glial_cell1.67354101
35MP0008872_abnormal_physiological_respon1.66826221
36MP0002909_abnormal_adrenal_gland1.63642661
37MP0005409_darkened_coat_color1.63424129
38MP0003329_amyloid_beta_deposits1.63150225
39MP0001324_abnormal_eye_pigmentation1.61481169
40MP0002102_abnormal_ear_morphology1.58619702
41MP0004142_abnormal_muscle_tone1.58260079
42MP0002160_abnormal_reproductive_system1.57837406
43MP0000566_synostosis1.57172304
44MP0000778_abnormal_nervous_system1.52922221
45MP0002876_abnormal_thyroid_physiology1.49935959
46MP0010386_abnormal_urinary_bladder1.47863659
47MP0006292_abnormal_olfactory_placode1.47594187
48MP0002734_abnormal_mechanical_nocicepti1.47307826
49MP0001485_abnormal_pinna_reflex1.46107777
50MP0002882_abnormal_neuron_morphology1.45788901
51MP0002064_seizures1.44981956
52MP0000427_abnormal_hair_cycle1.43116399
53MP0002090_abnormal_vision1.42952324
54MP0001986_abnormal_taste_sensitivity1.40082552
55MP0003787_abnormal_imprinting1.39444756
56MP0002837_dystrophic_cardiac_calcinosis1.38538485
57MP0000372_irregular_coat_pigmentation1.32324288
58MP0002928_abnormal_bile_duct1.31380428
59MP0005084_abnormal_gallbladder_morpholo1.28587615
60MP0001963_abnormal_hearing_physiology1.28213536
61MP0009046_muscle_twitch1.26665016
62MP0004147_increased_porphyrin_level1.25673923
63MP0004019_abnormal_vitamin_homeostasis1.24979218
64MP0002557_abnormal_social/conspecific_i1.19282403
65MP0005646_abnormal_pituitary_gland1.17203744
66MP0005389_reproductive_system_phenotype1.15843303
67MP0005332_abnormal_amino_acid1.15349919
68MP0001188_hyperpigmentation1.15147614
69MP0000538_abnormal_urinary_bladder1.13446234
70MP0003656_abnormal_erythrocyte_physiolo1.12742824
71MP0001502_abnormal_circadian_rhythm1.12643662
72MP0000026_abnormal_inner_ear1.11747824
73MP0002277_abnormal_respiratory_mucosa1.11646818
74MP0001756_abnormal_urination1.10248618
75MP0008995_early_reproductive_senescence1.07569361
76MP0001765_abnormal_ion_homeostasis1.07027982
77MP0003698_abnormal_male_reproductive1.05764308
78MP0003632_abnormal_nervous_system1.05680505
79MP0009745_abnormal_behavioral_response1.05050451
80MP0000647_abnormal_sebaceous_gland1.04790277
81MP0005083_abnormal_biliary_tract1.03493812
82MP0003635_abnormal_synaptic_transmissio1.03040537
83MP0003195_calcinosis1.02649755
84MP0002067_abnormal_sensory_capabilities1.01999305
85MP0002572_abnormal_emotion/affect_behav1.00680417
86MP0005645_abnormal_hypothalamus_physiol1.00127434
87MP0005499_abnormal_olfactory_system0.99541704
88MP0005394_taste/olfaction_phenotype0.99541704
89MP0001346_abnormal_lacrimal_gland0.99297630
90MP0001661_extended_life_span0.97768732
91MP0003119_abnormal_digestive_system0.96680546
92MP0004134_abnormal_chest_morphology0.95955682
93MP0000462_abnormal_digestive_system0.95228713
94MP0005365_abnormal_bile_salt0.94238228
95MP0001968_abnormal_touch/_nociception0.93389980
96MP0001919_abnormal_reproductive_system0.93327484
97MP0002822_catalepsy0.91512621
98MP0000762_abnormal_tongue_morphology0.88632077
99MP0002163_abnormal_gland_morphology0.88569792
100MP0003631_nervous_system_phenotype0.88293946
101MP0003938_abnormal_ear_development0.87191647
102MP0001501_abnormal_sleep_pattern0.86815122
103MP0000955_abnormal_spinal_cord0.85993897
104MP0001970_abnormal_pain_threshold0.84896882
105MP0002210_abnormal_sex_determination0.84797187
106MP0001440_abnormal_grooming_behavior0.83521202
107MP0001944_abnormal_pancreas_morphology0.83069383
108MP0001984_abnormal_olfaction0.83065190
109MP0004145_abnormal_muscle_electrophysio0.83055745
110MP0000467_abnormal_esophagus_morphology0.82691052
111MP0003137_abnormal_impulse_conducting0.82015909
112MP0009250_abnormal_appendicular_skeleto0.81952266
113MP0003937_abnormal_limbs/digits/tail_de0.81636674
114MP0002066_abnormal_motor_capabilities/c0.81122828
115MP0002736_abnormal_nociception_after0.80690988
116MP0003283_abnormal_digestive_organ0.80674053
117MP0002938_white_spotting0.79836479
118MP0003633_abnormal_nervous_system0.79408878
119MP0008569_lethality_at_weaning0.79254512
120MP0005451_abnormal_body_composition0.79021843
121MP0002063_abnormal_learning/memory/cond0.78975001
122MP0001299_abnormal_eye_distance/0.78595294
123MP0009379_abnormal_foot_pigmentation0.76057581
124MP0008260_abnormal_autophagy0.75664115
125MP0000631_abnormal_neuroendocrine_gland0.72533378
126MP0000579_abnormal_nail_morphology0.70168637
127MP0004859_abnormal_synaptic_plasticity0.67060661
128MP0010678_abnormal_skin_adnexa0.66714190
129MP0005386_behavior/neurological_phenoty0.65115045
130MP0004924_abnormal_behavior0.65115045
131MP0002152_abnormal_brain_morphology0.64643877
132MP0001340_abnormal_eyelid_morphology0.63943652
133MP0008789_abnormal_olfactory_epithelium0.63607388
134MP0001764_abnormal_homeostasis0.63601263
135MP0000383_abnormal_hair_follicle0.62694061
136MP0001929_abnormal_gametogenesis0.62177766
137MP0006276_abnormal_autonomic_nervous0.61927119
138MP0005623_abnormal_meninges_morphology0.58988880
139MP0003806_abnormal_nucleotide_metabolis0.58806638
140MP0002735_abnormal_chemical_nociception0.58669161
141MP0000749_muscle_degeneration0.57944818
142MP0002733_abnormal_thermal_nociception0.57559962
143MP0001851_eye_inflammation0.56681093
144MP0002295_abnormal_pulmonary_circulatio0.56636589

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)7.23256053
2Bony spicule pigmentary retinopathy (HP:0007737)6.33381730
3Abnormal rod and cone electroretinograms (HP:0008323)5.32537958
4Absent rod-and cone-mediated responses on ERG (HP:0007688)5.05125678
5Attenuation of retinal blood vessels (HP:0007843)4.67626489
6Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.56543359
7Degeneration of the lateral corticospinal tracts (HP:0002314)4.56543359
8Chorioretinal atrophy (HP:0000533)4.45296050
9Abnormality of midbrain morphology (HP:0002418)4.29954591
10Molar tooth sign on MRI (HP:0002419)4.29954591
11Abolished electroretinogram (ERG) (HP:0000550)4.25248526
12Pancreatic fibrosis (HP:0100732)4.18341523
13Decreased central vision (HP:0007663)4.13656370
14Pancreatic cysts (HP:0001737)4.12171647
15Neurofibrillary tangles (HP:0002185)4.08777749
16Dyschromatopsia (HP:0007641)4.03180651
17Abnormality of macular pigmentation (HP:0008002)3.93156391
18Keratoconus (HP:0000563)3.70781690
19Increased corneal curvature (HP:0100692)3.70781690
20Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.64417641
21Parakeratosis (HP:0001036)3.59822225
22Pigmentary retinal degeneration (HP:0001146)3.55569599
23Central scotoma (HP:0000603)3.51735582
24Chronic bronchitis (HP:0004469)3.42716270
25Dynein arm defect of respiratory motile cilia (HP:0012255)3.32498996
26Absent/shortened dynein arms (HP:0200106)3.32498996
27Scotoma (HP:0000575)3.27326889
28Peripheral hypomyelination (HP:0007182)3.19719540
29Retinitis pigmentosa (HP:0000510)3.19551948
30Cone-rod dystrophy (HP:0000548)3.18028085
31Abnormality of the corticospinal tract (HP:0002492)3.17857393
32Abnormality of the renal medulla (HP:0100957)3.17078361
33Sensory axonal neuropathy (HP:0003390)3.16731528
34Pendular nystagmus (HP:0012043)3.15129781
35Choroideremia (HP:0001139)3.12786290
36Cystic liver disease (HP:0006706)3.08599196
37Tubular atrophy (HP:0000092)3.05465702
38Chronic hepatic failure (HP:0100626)3.03424553
39Bronchiectasis (HP:0002110)2.99995010
40Rib fusion (HP:0000902)2.97152824
41Type II lissencephaly (HP:0007260)2.92194877
42Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.89072755
43Gait imbalance (HP:0002141)2.78667760
44Medial flaring of the eyebrow (HP:0010747)2.75462881
45Congenital sensorineural hearing impairment (HP:0008527)2.75318916
46Abnormal respiratory motile cilium physiology (HP:0012261)2.75005819
47Cerebral inclusion bodies (HP:0100314)2.74258766
48Photophobia (HP:0000613)2.72939650
49Occipital encephalocele (HP:0002085)2.67482576
50Type II diabetes mellitus (HP:0005978)2.67364754
51Optic disc pallor (HP:0000543)2.67141120
52Cerebral hypomyelination (HP:0006808)2.67032238
53Vaginal atresia (HP:0000148)2.66071721
54Congenital primary aphakia (HP:0007707)2.65903282
55Onion bulb formation (HP:0003383)2.65161139
56Polydipsia (HP:0001959)2.63173408
57Abnormal drinking behavior (HP:0030082)2.63173408
58Abnormal ciliary motility (HP:0012262)2.63104836
59Decreased circulating renin level (HP:0003351)2.62309002
60Genital tract atresia (HP:0001827)2.56990750
61Testicular atrophy (HP:0000029)2.52692533
62Congenital hepatic fibrosis (HP:0002612)2.41364592
63Sclerocornea (HP:0000647)2.37431265
64Abnormality of the renal cortex (HP:0011035)2.37300605
65Abnormal respiratory epithelium morphology (HP:0012253)2.36334015
66Abnormal respiratory motile cilium morphology (HP:0005938)2.36334015
67Male pseudohermaphroditism (HP:0000037)2.33979300
68Retinal dysplasia (HP:0007973)2.31911843
69Mitochondrial inheritance (HP:0001427)2.29698434
70Macular degeneration (HP:0000608)2.29630056
71Anencephaly (HP:0002323)2.28534495
72Nephrogenic diabetes insipidus (HP:0009806)2.27259858
73Hypoplastic pelvis (HP:0008839)2.25468874
74Concave nail (HP:0001598)2.25039391
75Infertility (HP:0000789)2.23581781
76Hypoplasia of the pons (HP:0012110)2.21349175
77Thickened helices (HP:0000391)2.20634358
78Vitreoretinal degeneration (HP:0000655)2.19978107
79Intention tremor (HP:0002080)2.18237379
80Hepatocellular necrosis (HP:0001404)2.16739354
81Abnormal auditory evoked potentials (HP:0006958)2.15436388
82Alacrima (HP:0000522)2.13781978
83Decreased electroretinogram (ERG) amplitude (HP:0000654)2.13491629
84Absent septum pellucidum (HP:0001331)2.12127152
85Aplasia/Hypoplasia of the tongue (HP:0010295)2.11520941
86Abnormality of the pons (HP:0007361)2.09876944
87Congenital ichthyosiform erythroderma (HP:0007431)2.09341690
88Severe visual impairment (HP:0001141)2.08902894
89Aplasia/Hypoplasia of the lens (HP:0008063)2.08612004
90Increased CSF lactate (HP:0002490)2.07507727
91Postaxial foot polydactyly (HP:0001830)2.06797842
92Cerebellar dysplasia (HP:0007033)2.06572419
93Spastic gait (HP:0002064)2.03176772
94Polyuria (HP:0000103)2.02626671
95Bile duct proliferation (HP:0001408)2.02363501
96Abnormal biliary tract physiology (HP:0012439)2.02363501
97Dysmetria (HP:0001310)2.01259717
98Split foot (HP:0001839)2.00696753
99Patellar aplasia (HP:0006443)1.99919205
100Furrowed tongue (HP:0000221)1.99203491
101Confusion (HP:0001289)1.99033765
102Supranuclear gaze palsy (HP:0000605)1.97762172
103Aplasia/Hypoplasia of the patella (HP:0006498)1.97395620
104Congenital, generalized hypertrichosis (HP:0004540)1.97215384
105Aplasia involving bones of the upper limbs (HP:0009823)1.97128129
106Aplasia of the phalanges of the hand (HP:0009802)1.97128129
107Aplasia involving bones of the extremities (HP:0009825)1.97128129
108Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.96032100
109Abnormality of alanine metabolism (HP:0010916)1.96032100
110Hyperalaninemia (HP:0003348)1.96032100
111Acute necrotizing encephalopathy (HP:0006965)1.95497260
112Nasal polyposis (HP:0100582)1.95177926
113Hepatic necrosis (HP:0002605)1.94731344
114Aplasia/Hypoplasia of the spleen (HP:0010451)1.94152065
115Lipid accumulation in hepatocytes (HP:0006561)1.93972672
116Retinal atrophy (HP:0001105)1.93812558
117Chronic sinusitis (HP:0011109)1.93729327
118Abnormal albumin level (HP:0012116)1.93012967
119Hypoalbuminemia (HP:0003073)1.93012967
120Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.91084964
121Leukodystrophy (HP:0002415)1.90051119
122Increased hepatocellular lipid droplets (HP:0006565)1.89509064
123Delusions (HP:0000746)1.88663422
124Absent thumb (HP:0009777)1.84765292
125Mesangial abnormality (HP:0001966)1.84514561
126Poor coordination (HP:0002370)1.84303096
127Rhinitis (HP:0012384)1.82480514
128Methylmalonic acidemia (HP:0002912)1.80509025
129Clumsiness (HP:0002312)1.80403378
130Renal Fanconi syndrome (HP:0001994)1.79342128
131Asplenia (HP:0001746)1.78907406
132Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.78160935
133Scanning speech (HP:0002168)1.77249344
134Abnormal mitochondria in muscle tissue (HP:0008316)1.77003833
135Abnormality of the septum pellucidum (HP:0007375)1.76715531
136Abnormal number of erythroid precursors (HP:0012131)1.76521100
137Abnormality of renin-angiotensin system (HP:0000847)1.76117861
138Humeroradial synostosis (HP:0003041)1.75006390
139Synostosis involving the elbow (HP:0003938)1.75006390
140Ketoacidosis (HP:0001993)1.73977150
141Large for gestational age (HP:0001520)1.73289597
142Male infertility (HP:0003251)1.72565324
1433-Methylglutaconic aciduria (HP:0003535)1.71957617
144True hermaphroditism (HP:0010459)1.71468697
145Acute encephalopathy (HP:0006846)1.70240162
146Hyperventilation (HP:0002883)1.68227246
147Preaxial hand polydactyly (HP:0001177)1.68167847
148Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.67770713
149Nephronophthisis (HP:0000090)1.67494669
150Progressive macrocephaly (HP:0004481)1.66715286
151Inability to walk (HP:0002540)1.66607203
152Septo-optic dysplasia (HP:0100842)1.65678532
153Abnormal urine output (HP:0012590)1.65222690
154Stage 5 chronic kidney disease (HP:0003774)1.65219319
155Anteriorly placed anus (HP:0001545)1.65032181
156Hypophosphatemic rickets (HP:0004912)1.64778844
157Abnormality of the middle phalanges of the toes (HP:0010183)1.64511501
158Abnormality of renal excretion (HP:0011036)1.64301575
159Aplasia/hypoplasia of the uterus (HP:0008684)1.64186761
160Decreased motor nerve conduction velocity (HP:0003431)1.63931605
161Decreased lacrimation (HP:0000633)1.63328947
162Ankle clonus (HP:0011448)1.60934786
163Spastic paraparesis (HP:0002313)1.60341795
164Coronal craniosynostosis (HP:0004440)1.59810645
165Slow saccadic eye movements (HP:0000514)1.59285212
166Specific learning disability (HP:0001328)1.58809928
167Hemiparesis (HP:0001269)1.58038073
168Megalencephaly (HP:0001355)1.57995753
169Epileptic encephalopathy (HP:0200134)1.57138110
170CNS hypomyelination (HP:0003429)1.56889906
171Increased serum pyruvate (HP:0003542)1.55804487
172Abnormality of glycolysis (HP:0004366)1.55804487

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.36928975
2PBK4.02163850
3FRK3.78341141
4OXSR13.33090314
5CASK2.90533755
6ZAK2.88160045
7EPHB12.82694910
8GRK12.70647327
9PKN12.70403601
10MAPKAPK52.62901788
11MAP4K22.40453517
12WNK42.32598930
13MAPK152.31320284
14TLK12.06829165
15PNCK1.96585161
16BCR1.90099080
17MET1.71954671
18WNK11.65924907
19TESK21.64868486
20IRAK21.63466620
21UHMK11.62803140
22MST41.61393542
23ACVR1B1.60806090
24DAPK21.58581516
25MAPKAPK31.49785078
26TNIK1.49199747
27TAOK31.48839775
28MUSK1.48106222
29NEK61.42366709
30CAMK2B1.41252517
31ICK1.38617528
32FGFR21.35782627
33CSNK1G31.35681502
34MAP2K61.34060838
35EPHA21.33901679
36CAMK2D1.32470440
37SIK21.27895699
38MAP3K41.26998399
39CSNK1A1L1.26573642
40VRK21.25845604
41SGK4941.25139002
42SGK2231.25139002
43ROCK21.19848726
44LIMK11.18670154
45FGR1.17714066
46CSNK1G11.17085832
47PRKCI1.14429868
48TRIM281.12808941
49NTRK11.08895260
50DYRK21.08037041
51NTRK31.07275565
52STK161.07176273
53CDK191.04102138
54MARK11.02466205
55MAP2K71.01049214
56BMPR1B1.00419935
57PRKCG0.98133003
58CSNK1G20.97018189
59PRPF4B0.95671948
60NUAK10.91925797
61RPS6KA50.90645408
62CAMK2A0.90037269
63CLK10.86527034
64CAMK2G0.84044784
65EPHA40.83215370
66TGFBR10.82842495
67PRKD30.81985101
68MKNK10.79834183
69PINK10.79441365
70MAP2K20.77743259
71IRAK10.76803005
72STK110.73637683
73TYRO30.71286433
74PRKCE0.70636586
75CDK50.70117732
76MARK20.69038114
77GRK60.68892322
78DYRK1A0.67952970
79NEK20.67442417
80MKNK20.66971511
81PAK60.65609719
82CDK30.64178125
83MAPK130.63158914
84PRKCQ0.62653523
85PTK2B0.61748983
86PHKG20.60523220
87PHKG10.60523220
88PRKG10.58262179
89CDK140.58083239
90AKT30.57981755
91NTRK20.57891654
92PRKD20.56166002
93PRKD10.56112519
94CSNK1D0.55922305
95IKBKB0.55568851
96HIPK20.54425754
97BCKDK0.53514822
98ERBB40.52564417
99CDK150.51617277
100MAP2K40.51185698
101PIK3CA0.50985307
102ADRBK10.50823156
103CAMK1G0.49077635
104FES0.49055258
105TAF10.47306461
106TRPM70.47243942
107CDK11A0.46988082
108STK38L0.46751332
109PRKACA0.45922488
110CDK180.45805611
111PLK20.45609932
112CHEK20.45409136
113GRK70.44951228
114INSRR0.44767303
115PRKCZ0.44202769
116PDPK10.44027259
117CSNK1A10.43991020
118ADRBK20.43349099
119MAPK120.42796840
120RPS6KA20.42435283
121PASK0.42361685
122GSK3A0.42097428
123RPS6KA60.41270897
124ERBB20.40386121
125PDK20.39821045
126TIE10.39397306
127BRAF0.39117156
128NME10.38693421
129PRKACB0.38290590
130PRKCA0.38255898
131PLK10.38056068
132BMPR20.37710130
133PAK30.36873775
134WNK30.35853451
135VRK10.35633860
136CAMK10.34600365
137TXK0.34547258
138DDR20.33783293
139EPHB20.33062014
140FYN0.31640411
141CHUK0.30766448
142PRKAA10.28913203
143DAPK10.27063823
144CAMKK10.27007490
145AURKA0.24176824
146TNK20.23525285
147GRK50.22886124
148BLK0.22323340
149ATR0.20290505

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047447.92674911
2Fatty acid elongation_Homo sapiens_hsa000623.80734491
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.51926442
4Steroid biosynthesis_Homo sapiens_hsa001003.24029043
5Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.02603959
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.69693743
7Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.50002664
8Ether lipid metabolism_Homo sapiens_hsa005652.48209076
9Sulfur metabolism_Homo sapiens_hsa009202.26178863
10Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.25768915
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.20107364
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.15894027
13Sulfur relay system_Homo sapiens_hsa041222.07066339
14Linoleic acid metabolism_Homo sapiens_hsa005911.90525560
15Oxidative phosphorylation_Homo sapiens_hsa001901.90210407
16Caffeine metabolism_Homo sapiens_hsa002321.83096943
17Protein export_Homo sapiens_hsa030601.74869279
18Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.73843920
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.72653364
20Vitamin B6 metabolism_Homo sapiens_hsa007501.59492555
21Histidine metabolism_Homo sapiens_hsa003401.59438592
22Sphingolipid metabolism_Homo sapiens_hsa006001.58668117
23Selenocompound metabolism_Homo sapiens_hsa004501.53656551
24Homologous recombination_Homo sapiens_hsa034401.49335358
25Nitrogen metabolism_Homo sapiens_hsa009101.46060877
26RNA polymerase_Homo sapiens_hsa030201.45632912
27Fanconi anemia pathway_Homo sapiens_hsa034601.43609857
28GABAergic synapse_Homo sapiens_hsa047271.36277601
29Parkinsons disease_Homo sapiens_hsa050121.32688630
30Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.31377526
31Tryptophan metabolism_Homo sapiens_hsa003801.29724545
32Alzheimers disease_Homo sapiens_hsa050101.24017084
33Ribosome_Homo sapiens_hsa030101.23846117
34Serotonergic synapse_Homo sapiens_hsa047261.23070382
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.19723683
36Retinol metabolism_Homo sapiens_hsa008301.18677232
37Glutamatergic synapse_Homo sapiens_hsa047241.13590745
38Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.13299749
39Arachidonic acid metabolism_Homo sapiens_hsa005901.05627320
40Axon guidance_Homo sapiens_hsa043601.02426970
41Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.01197466
42Butanoate metabolism_Homo sapiens_hsa006500.99959350
43Huntingtons disease_Homo sapiens_hsa050160.98490920
44beta-Alanine metabolism_Homo sapiens_hsa004100.97430540
45Cardiac muscle contraction_Homo sapiens_hsa042600.97185255
46Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.91678533
47Primary bile acid biosynthesis_Homo sapiens_hsa001200.86434326
48Morphine addiction_Homo sapiens_hsa050320.85105931
49Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84244737
50Arginine and proline metabolism_Homo sapiens_hsa003300.83532174
51Cocaine addiction_Homo sapiens_hsa050300.80579247
52SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78926207
53ABC transporters_Homo sapiens_hsa020100.78674238
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77186153
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.74427047
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.74037454
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73820469
58Glycerophospholipid metabolism_Homo sapiens_hsa005640.73284353
59Collecting duct acid secretion_Homo sapiens_hsa049660.73193114
60Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.72738510
61Glutathione metabolism_Homo sapiens_hsa004800.72513408
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.71153307
63Chemical carcinogenesis_Homo sapiens_hsa052040.69771308
64Fatty acid biosynthesis_Homo sapiens_hsa000610.69319183
65Circadian entrainment_Homo sapiens_hsa047130.68577752
66Hedgehog signaling pathway_Homo sapiens_hsa043400.68258672
67Mineral absorption_Homo sapiens_hsa049780.68148813
68RNA degradation_Homo sapiens_hsa030180.67641956
69Fatty acid metabolism_Homo sapiens_hsa012120.67025971
70Long-term depression_Homo sapiens_hsa047300.66994544
71Alcoholism_Homo sapiens_hsa050340.65426105
72Purine metabolism_Homo sapiens_hsa002300.64073499
73Phenylalanine metabolism_Homo sapiens_hsa003600.62925662
74Nicotine addiction_Homo sapiens_hsa050330.62672452
75Salivary secretion_Homo sapiens_hsa049700.62048550
76Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61534301
77Calcium signaling pathway_Homo sapiens_hsa040200.59813146
78Folate biosynthesis_Homo sapiens_hsa007900.57074096
79Dopaminergic synapse_Homo sapiens_hsa047280.56903105
80Pancreatic secretion_Homo sapiens_hsa049720.56882517
81Regulation of autophagy_Homo sapiens_hsa041400.56430092
82Synaptic vesicle cycle_Homo sapiens_hsa047210.56328409
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56208696
84Renin secretion_Homo sapiens_hsa049240.56084756
85Vascular smooth muscle contraction_Homo sapiens_hsa042700.56063084
86Insulin secretion_Homo sapiens_hsa049110.55294812
87Fatty acid degradation_Homo sapiens_hsa000710.54536751
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54357631
89Pyrimidine metabolism_Homo sapiens_hsa002400.54200189
90Vitamin digestion and absorption_Homo sapiens_hsa049770.54168725
91Ovarian steroidogenesis_Homo sapiens_hsa049130.53915396
92Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53163332
93Metabolic pathways_Homo sapiens_hsa011000.52884452
94Propanoate metabolism_Homo sapiens_hsa006400.51753005
95Cholinergic synapse_Homo sapiens_hsa047250.51368789
96Taste transduction_Homo sapiens_hsa047420.50409449
97Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.49238699
98Tight junction_Homo sapiens_hsa045300.47631609
99Peroxisome_Homo sapiens_hsa041460.46699795
100Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46062930
101Basal transcription factors_Homo sapiens_hsa030220.45270785
102Renal cell carcinoma_Homo sapiens_hsa052110.45209009
103Glycerolipid metabolism_Homo sapiens_hsa005610.44771979
104Tyrosine metabolism_Homo sapiens_hsa003500.44184047
105One carbon pool by folate_Homo sapiens_hsa006700.43465293
106Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.43430794
107Ras signaling pathway_Homo sapiens_hsa040140.43425728
108Proteasome_Homo sapiens_hsa030500.43021800
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.41038909
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.40933341
111Vibrio cholerae infection_Homo sapiens_hsa051100.40476667
112Olfactory transduction_Homo sapiens_hsa047400.40146999
113Dorso-ventral axis formation_Homo sapiens_hsa043200.39409768
114Pyruvate metabolism_Homo sapiens_hsa006200.39364105
115Amphetamine addiction_Homo sapiens_hsa050310.37558621
116Gastric acid secretion_Homo sapiens_hsa049710.36324455
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36128564
118Basal cell carcinoma_Homo sapiens_hsa052170.34880395
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34680455
120Systemic lupus erythematosus_Homo sapiens_hsa053220.33920504
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33576833
122Base excision repair_Homo sapiens_hsa034100.32973172
123Fructose and mannose metabolism_Homo sapiens_hsa000510.32557522
124Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32536221
125Cyanoamino acid metabolism_Homo sapiens_hsa004600.32269670
126Circadian rhythm_Homo sapiens_hsa047100.29927632
127Fat digestion and absorption_Homo sapiens_hsa049750.28071369
128Wnt signaling pathway_Homo sapiens_hsa043100.26260579
129Autoimmune thyroid disease_Homo sapiens_hsa053200.25852876
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25751119
131cAMP signaling pathway_Homo sapiens_hsa040240.25654933

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