CCDC25

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.13660723
2negative regulation of cell killing (GO:0031342)6.13660723
3regulation of activation of Janus kinase activity (GO:0010533)5.20289387
4eosinophil chemotaxis (GO:0048245)4.36708895
5protein neddylation (GO:0045116)4.10330327
6regulation of chronic inflammatory response (GO:0002676)4.02534327
7CENP-A containing nucleosome assembly (GO:0034080)4.01050879
8viral transcription (GO:0019083)4.00925161
9chromatin remodeling at centromere (GO:0031055)3.99323798
10translational termination (GO:0006415)3.98571673
11ribosomal small subunit assembly (GO:0000028)3.85920473
12eosinophil migration (GO:0072677)3.81180085
13proteasome assembly (GO:0043248)3.80398793
14mitotic metaphase plate congression (GO:0007080)3.74819827
15positive regulation of translational initiation (GO:0045948)3.72776683
16SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.66724716
17cotranslational protein targeting to membrane (GO:0006613)3.66293623
18cellular response to exogenous dsRNA (GO:0071360)3.63561731
19protein targeting to ER (GO:0045047)3.60079910
20positive regulation of monocyte chemotaxis (GO:0090026)3.59889944
21indolalkylamine catabolic process (GO:0046218)3.56727615
22tryptophan catabolic process (GO:0006569)3.56727615
23indole-containing compound catabolic process (GO:0042436)3.56727615
24positive regulation of T cell cytokine production (GO:0002726)3.54990165
25natural killer cell activation involved in immune response (GO:0002323)3.53121739
26establishment of protein localization to endoplasmic reticulum (GO:0072599)3.49340437
27protein localization to kinetochore (GO:0034501)3.45614080
28positive regulation of histone H3-K4 methylation (GO:0051571)3.43447088
29protein localization to endoplasmic reticulum (GO:0070972)3.39162957
30histone exchange (GO:0043486)3.38770912
31deoxyribose phosphate biosynthetic process (GO:0046385)3.37134380
322-deoxyribonucleotide biosynthetic process (GO:0009265)3.37134380
33ribosomal small subunit biogenesis (GO:0042274)3.37014504
34establishment of integrated proviral latency (GO:0075713)3.36934394
35mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.36740097
36translational elongation (GO:0006414)3.31577833
37translational initiation (GO:0006413)3.28328388
38glycoside metabolic process (GO:0016137)3.27878155
39deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.27642639
40metaphase plate congression (GO:0051310)3.24467911
41ribosomal large subunit biogenesis (GO:0042273)3.23377844
42termination of RNA polymerase III transcription (GO:0006386)3.22509449
43transcription elongation from RNA polymerase III promoter (GO:0006385)3.22509449
44protein deneddylation (GO:0000338)3.22363083
45centriole replication (GO:0007099)3.22267947
46maturation of SSU-rRNA (GO:0030490)3.22016808
47cullin deneddylation (GO:0010388)3.18470178
48tryptophan metabolic process (GO:0006568)3.17429183
49regulation of cellular amino acid metabolic process (GO:0006521)3.16231816
50mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.15480973
51cellular protein complex disassembly (GO:0043624)3.15175831
52positive regulation of viral genome replication (GO:0045070)3.14384004
53organelle disassembly (GO:1903008)3.13465496
54DNA replication-independent nucleosome organization (GO:0034724)3.11147583
55DNA replication-independent nucleosome assembly (GO:0006336)3.11147583
56deoxyribonucleotide biosynthetic process (GO:0009263)3.10878030
57nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.08988420
58viral life cycle (GO:0019058)3.06242505
59regulation of meiosis I (GO:0060631)3.04118536
60protein complex biogenesis (GO:0070271)3.04104403
61aromatic amino acid family catabolic process (GO:0009074)3.03531966
62kinetochore organization (GO:0051383)3.03256408
637-methylguanosine mRNA capping (GO:0006370)2.99706478
64neutrophil activation involved in immune response (GO:0002283)2.98643321
65purine nucleobase biosynthetic process (GO:0009113)2.97237223
66mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.97079457
67mitochondrial respiratory chain complex I assembly (GO:0032981)2.97079457
68NADH dehydrogenase complex assembly (GO:0010257)2.97079457
697-methylguanosine RNA capping (GO:0009452)2.95820334
70RNA capping (GO:0036260)2.95820334
71antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.95680052
72DNA replication checkpoint (GO:0000076)2.95667594
73regulation of DNA methylation (GO:0044030)2.95177967
74protein-cofactor linkage (GO:0018065)2.94496037
75antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.94297272
76establishment of protein localization to mitochondrial membrane (GO:0090151)2.93905807
77mitochondrial respiratory chain complex assembly (GO:0033108)2.93656239
78energy coupled proton transport, down electrochemical gradient (GO:0015985)2.91822860
79ATP synthesis coupled proton transport (GO:0015986)2.91822860
80ribonucleoprotein complex disassembly (GO:0032988)2.90887374
81positive regulation of mast cell activation (GO:0033005)2.90055508
82protein localization to chromosome, centromeric region (GO:0071459)2.89264389
83aldehyde catabolic process (GO:0046185)2.87948029
84telomere maintenance via semi-conservative replication (GO:0032201)2.87870546
85regulation of mononuclear cell migration (GO:0071675)2.87663496
86DNA strand elongation involved in DNA replication (GO:0006271)2.84993444
87regulation of response to tumor cell (GO:0002834)2.84770992
88positive regulation of response to tumor cell (GO:0002836)2.84770992
89positive regulation of immune response to tumor cell (GO:0002839)2.84770992
90regulation of immune response to tumor cell (GO:0002837)2.84770992
91nucleotide-excision repair, DNA gap filling (GO:0006297)2.84603586
92kinetochore assembly (GO:0051382)2.84123334
93translation (GO:0006412)2.83995693
94meiotic cell cycle (GO:0051321)2.82702999
95amine catabolic process (GO:0009310)2.82634802
96cellular biogenic amine catabolic process (GO:0042402)2.82634802
97synapsis (GO:0007129)2.82106829
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.79877113
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.79877113
100signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.79877113
101DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.79121937
102chaperone-mediated protein transport (GO:0072321)2.78905744
103intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.78623912
104signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.78623912
105negative regulation by host of viral transcription (GO:0043922)2.78599294
106negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.78036829
107inner mitochondrial membrane organization (GO:0007007)2.75983834
108NAD biosynthetic process (GO:0009435)2.75978452
109indolalkylamine metabolic process (GO:0006586)2.75659319
110positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.74395063
111DNA ligation (GO:0006266)2.73963091
112positive regulation of T cell chemotaxis (GO:0010820)2.73662028
113regulation of T cell chemotaxis (GO:0010819)2.73662028
114regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.73401057
115DNA strand elongation (GO:0022616)2.72542250
116establishment of chromosome localization (GO:0051303)2.72404815
117neutrophil activation (GO:0042119)2.71077018
118respiratory electron transport chain (GO:0022904)2.70849865
119antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.70106477
120signal transduction involved in DNA integrity checkpoint (GO:0072401)2.69799361
121signal transduction involved in DNA damage checkpoint (GO:0072422)2.69799361
122transcription elongation from RNA polymerase I promoter (GO:0006362)2.69219942
123protein complex disassembly (GO:0043241)2.68688798
124signal transduction involved in cell cycle checkpoint (GO:0072395)2.68563016
125replication fork processing (GO:0031297)2.67801725
126mitotic chromosome condensation (GO:0007076)2.65757798
127retinal cone cell development (GO:0046549)2.65310452
128positive regulation of mitochondrial fission (GO:0090141)2.64283070
129water-soluble vitamin biosynthetic process (GO:0042364)2.64043616
130positive regulation of T cell apoptotic process (GO:0070234)2.63918919
131nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.62979533
132regulation of mitotic spindle checkpoint (GO:1903504)2.62960279
133regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.62960279
134exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.62076363
135macromolecular complex disassembly (GO:0032984)2.61803977
136electron transport chain (GO:0022900)2.60903093
137positive regulation of chromosome segregation (GO:0051984)2.60525191
138resolution of meiotic recombination intermediates (GO:0000712)2.60281842
139negative regulation of DNA-dependent DNA replication (GO:2000104)2.60189456
140production of molecular mediator involved in inflammatory response (GO:0002532)2.60155396
141granulocyte activation (GO:0036230)2.59508420
142positive regulation of gastrulation (GO:2000543)2.58553734
143positive regulation of cAMP-mediated signaling (GO:0043950)2.58030806
144termination of RNA polymerase I transcription (GO:0006363)2.57300191
145regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.55713361
146pteridine-containing compound biosynthetic process (GO:0042559)2.55400638
147rRNA modification (GO:0000154)2.55022049
148positive regulation of interferon-alpha production (GO:0032727)2.54928561
149positive regulation of mitotic sister chromatid separation (GO:1901970)2.54257860
150positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.54257860
151positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.54257860
152interferon-gamma production (GO:0032609)2.53992760
153negative regulation of T cell mediated immunity (GO:0002710)2.53889448
154mitotic recombination (GO:0006312)2.53455012
155regulation of cellular amine metabolic process (GO:0033238)2.53260605
156cellular component biogenesis (GO:0044085)2.52035517
157regulation of spindle organization (GO:0090224)2.51795612
158maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.51435718
159cellular response to interleukin-15 (GO:0071350)2.51270820
160transcription-coupled nucleotide-excision repair (GO:0006283)2.50622727
161telomere maintenance via recombination (GO:0000722)2.50114928
162nuclear-transcribed mRNA catabolic process (GO:0000956)2.50098140
163T cell migration (GO:0072678)2.49820306
164negative regulation of viral genome replication (GO:0045071)2.48633706
165respiratory chain complex IV assembly (GO:0008535)2.48114550
166DNA-dependent DNA replication (GO:0006261)2.47925841
167positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.46316662
168peptidyl-histidine modification (GO:0018202)2.45029109
169regulation of mitochondrial translation (GO:0070129)2.44458211
170oxidative phosphorylation (GO:0006119)2.43843362
171ribonucleoprotein complex biogenesis (GO:0022613)2.43758749
172positive regulation of T cell migration (GO:2000406)2.43705415
173DNA catabolic process, exonucleolytic (GO:0000738)2.43480459
174anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.43219819
175positive regulation of lymphocyte migration (GO:2000403)2.42834958
176DNA double-strand break processing (GO:0000729)2.42692065

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.71385407
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.54696781
3EZH2_22144423_ChIP-Seq_EOC_Human4.08023719
4* GABP_17652178_ChIP-ChIP_JURKAT_Human3.62070845
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.21465829
6* EST1_17652178_ChIP-ChIP_JURKAT_Human3.07247866
7BP1_19119308_ChIP-ChIP_Hs578T_Human3.06475830
8E2F7_22180533_ChIP-Seq_HELA_Human3.04105734
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.95682679
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.86095332
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.78412426
12IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.74916200
13EGR1_23403033_ChIP-Seq_LIVER_Mouse2.74887576
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.70522367
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.68025760
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.51353576
17IRF8_22096565_ChIP-ChIP_GC-B_Human2.38779917
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.36444206
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.34988382
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.33765309
21PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.31862067
22CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.27765923
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.22614616
24ETS1_20019798_ChIP-Seq_JURKAT_Human2.22078097
25FOXM1_23109430_ChIP-Seq_U2OS_Human2.12089821
26ELK1_19687146_ChIP-ChIP_HELA_Human2.10367105
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.07211518
28* VDR_23849224_ChIP-Seq_CD4+_Human2.06673822
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.06124361
30FLI1_27457419_Chip-Seq_LIVER_Mouse2.01328436
31CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.88080269
32* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.83955346
33MYC_18555785_ChIP-Seq_MESCs_Mouse1.82753103
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.82436837
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.77272902
36CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75310113
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.73558809
38IRF1_19129219_ChIP-ChIP_H3396_Human1.72219448
39DCP1A_22483619_ChIP-Seq_HELA_Human1.71455175
40TAF15_26573619_Chip-Seq_HEK293_Human1.71126689
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.66715282
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.66346964
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65763357
44ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.64287689
45PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60940653
46ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59838987
47* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56557481
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.54121892
49STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.53717421
50* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.53275806
51* FOXP3_21729870_ChIP-Seq_TREG_Human1.51684650
52E2F1_18555785_ChIP-Seq_MESCs_Mouse1.48690796
53FUS_26573619_Chip-Seq_HEK293_Human1.47301874
54HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.45612200
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.40725787
56MYC_18358816_ChIP-ChIP_MESCs_Mouse1.39578456
57VDR_22108803_ChIP-Seq_LS180_Human1.39425659
58NELFA_20434984_ChIP-Seq_ESCs_Mouse1.38508648
59SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35685724
60* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.35639323
61THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35565126
62ELF1_17652178_ChIP-ChIP_JURKAT_Human1.34164997
63KAP1_22055183_ChIP-Seq_ESCs_Mouse1.33687368
64HTT_18923047_ChIP-ChIP_STHdh_Human1.33259519
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.32357880
66SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31758111
67STAT4_19710469_ChIP-ChIP_TH1__Mouse1.25810959
68POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.25730876
69AR_21909140_ChIP-Seq_LNCAP_Human1.25224423
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20548831
71GATA1_22025678_ChIP-Seq_K562_Human1.20048567
72FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.18182990
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.16723759
74HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.13333502
75E2F1_21310950_ChIP-Seq_MCF-7_Human1.13125442
76MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13103435
77* GABP_19822575_ChIP-Seq_HepG2_Human1.12529012
78* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11490005
79RUNX1_27457419_Chip-Seq_LIVER_Mouse1.10887058
80HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10185869
81MYC_18940864_ChIP-ChIP_HL60_Human1.10124321
82XRN2_22483619_ChIP-Seq_HELA_Human1.09161115
83SUZ12_18555785_Chip-Seq_ESCs_Mouse1.08969332
84P300_19829295_ChIP-Seq_ESCs_Human1.08445742
85EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07848456
86STAT3_18555785_Chip-Seq_ESCs_Mouse1.06705943
87GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06626240
88MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.06412376
89RXR_22158963_ChIP-Seq_LIVER_Mouse1.06058496
90EZH2_27294783_Chip-Seq_NPCs_Mouse1.06023877
91GBX2_23144817_ChIP-Seq_PC3_Human1.05928100
92SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.03435083
93NMYC_18555785_Chip-Seq_ESCs_Mouse1.03167570
94NOTCH1_21737748_ChIP-Seq_TLL_Human1.02741446
95* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02618218
96SOX2_18555785_Chip-Seq_ESCs_Mouse1.02262153
97EWS_26573619_Chip-Seq_HEK293_Human1.02021514
98SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.01317595
99IRF8_27001747_Chip-Seq_BMDM_Mouse1.00655205
100CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99646516
101MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99205933
102P53_22387025_ChIP-Seq_ESCs_Mouse0.98469889
103TP53_22573176_ChIP-Seq_HFKS_Human0.98033363
104NANOG_18555785_Chip-Seq_ESCs_Mouse0.97897676
105IGF1R_20145208_ChIP-Seq_DFB_Human0.97556505
106SMAD1_18555785_Chip-Seq_ESCs_Mouse0.97201498
107ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.96750940
108CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96280525
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96147130
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.96004311
111* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94830360
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.94761619
113NANOG_18555785_ChIP-Seq_MESCs_Mouse0.94519734
114SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94112885
115* YY1_21170310_ChIP-Seq_MESCs_Mouse0.93916872
116EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.93858496
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.93572303
118PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92644919
119TTF2_22483619_ChIP-Seq_HELA_Human0.92637614
120ZNF274_21170338_ChIP-Seq_K562_Hela0.91998506
121OCT4_18555785_Chip-Seq_ESCs_Mouse0.91827460
122EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.91697670
123CMYC_18555785_Chip-Seq_ESCs_Mouse0.91050308
124LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91016011
125MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91013952
126GATA1_26923725_Chip-Seq_HPCs_Mouse0.90542717
127RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89842653
128BMI1_23680149_ChIP-Seq_NPCS_Mouse0.89221079
129* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89101928
130SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88419398
131SOX17_20123909_ChIP-Seq_XEN_Mouse0.88045071
132SOX2_16153702_ChIP-ChIP_HESCs_Human0.87764350
133FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.87477998
134P300_18555785_Chip-Seq_ESCs_Mouse0.86868976
135TOP2B_26459242_ChIP-Seq_MCF-7_Human0.86115453
136NANOG_19829295_ChIP-Seq_ESCs_Human0.85460576
137SOX2_19829295_ChIP-Seq_ESCs_Human0.85460576
138CBP_20019798_ChIP-Seq_JUKART_Human0.84661372
139IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.84661372
140TP63_19390658_ChIP-ChIP_HaCaT_Human0.83634394
141UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.83038561
142ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.81950317

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system3.50770761
2MP0009697_abnormal_copulation3.40934338
3MP0005085_abnormal_gallbladder_physiolo3.33886971
4MP0003806_abnormal_nucleotide_metabolis3.28311448
5MP0008875_abnormal_xenobiotic_pharmacok3.05305091
6MP0009785_altered_susceptibility_to2.77636199
7MP0002148_abnormal_hypersensitivity_rea2.73959420
8MP0005365_abnormal_bile_salt2.68951486
9MP0003693_abnormal_embryo_hatching2.62748702
10MP0005671_abnormal_response_to2.48221300
11MP0002876_abnormal_thyroid_physiology2.44792822
12MP0005360_urolithiasis2.41610508
13MP0010030_abnormal_orbit_morphology2.41531836
14MP0008789_abnormal_olfactory_epithelium2.41379968
15MP0003186_abnormal_redox_activity2.30003346
16MP0010386_abnormal_urinary_bladder2.26813027
17MP0006072_abnormal_retinal_apoptosis2.14465151
18MP0005408_hypopigmentation2.12031115
19MP0003436_decreased_susceptibility_to2.05863474
20MP0001293_anophthalmia2.05444756
21MP0003195_calcinosis1.99436845
22MP0005394_taste/olfaction_phenotype1.99197249
23MP0005499_abnormal_olfactory_system1.99197249
24MP0008057_abnormal_DNA_replication1.97592458
25MP0003724_increased_susceptibility_to1.97035632
26MP0002163_abnormal_gland_morphology1.95499881
27MP0003890_abnormal_embryonic-extraembry1.89697580
28MP0004782_abnormal_surfactant_physiolog1.85646389
29MP0002938_white_spotting1.84038795
30MP0005379_endocrine/exocrine_gland_phen1.79853427
31MP0006292_abnormal_olfactory_placode1.79051162
32MP0003718_maternal_effect1.74754234
33MP0001764_abnormal_homeostasis1.72918159
34MP0003121_genomic_imprinting1.70700802
35MP0001835_abnormal_antigen_presentation1.69574129
36MP0002160_abnormal_reproductive_system1.69357535
37MP0005000_abnormal_immune_tolerance1.69041647
38MP0006082_CNS_inflammation1.64854503
39MP0010329_abnormal_lipoprotein_level1.60004286
40MP0005084_abnormal_gallbladder_morpholo1.56331322
41MP0005310_abnormal_salivary_gland1.56200021
42MP0002277_abnormal_respiratory_mucosa1.55588722
43MP0008877_abnormal_DNA_methylation1.52845250
44MP0009764_decreased_sensitivity_to1.52459489
45MP0001984_abnormal_olfaction1.52041017
46MP0008058_abnormal_DNA_repair1.49184822
47MP0005025_abnormal_response_to1.48956633
48MP0003011_delayed_dark_adaptation1.47246423
49MP0002234_abnormal_pharynx_morphology1.46884057
50MP0001529_abnormal_vocalization1.46316211
51MP0008932_abnormal_embryonic_tissue1.46225510
52MP0003787_abnormal_imprinting1.45680860
53MP0006035_abnormal_mitochondrial_morpho1.41960813
54MP0006276_abnormal_autonomic_nervous1.39201401
55MP0002638_abnormal_pupillary_reflex1.38984665
56MP0000631_abnormal_neuroendocrine_gland1.35849358
57MP0003123_paternal_imprinting1.35823054
58MP0003122_maternal_imprinting1.35461411
59MP0002877_abnormal_melanocyte_morpholog1.35357976
60MP0001188_hyperpigmentation1.33872311
61MP0002723_abnormal_immune_serum1.33196619
62MP0003136_yellow_coat_color1.31907090
63MP0005083_abnormal_biliary_tract1.30216416
64MP0005332_abnormal_amino_acid1.29963128
65MP0002210_abnormal_sex_determination1.29573453
66MP0004957_abnormal_blastocyst_morpholog1.28782134
67MP0005395_other_phenotype1.27872742
68MP0002419_abnormal_innate_immunity1.26928930
69MP0002233_abnormal_nose_morphology1.23656115
70MP0002132_abnormal_respiratory_system1.23374969
71MP0003941_abnormal_skin_development1.23068789
72MP0000569_abnormal_digit_pigmentation1.19313628
73MP0001919_abnormal_reproductive_system1.19265430
74MP0008469_abnormal_protein_level1.18377066
75MP0002693_abnormal_pancreas_physiology1.18113370
76MP0003880_abnormal_central_pattern1.17740130
77MP0005389_reproductive_system_phenotype1.17607808
78MP0001800_abnormal_humoral_immune1.16789076
79MP0002102_abnormal_ear_morphology1.16534423
80MP0004019_abnormal_vitamin_homeostasis1.15505394
81MP0005551_abnormal_eye_electrophysiolog1.14752590
82MP0001929_abnormal_gametogenesis1.14018652
83MP0001661_extended_life_span1.13944457
84MP0002272_abnormal_nervous_system1.13548539
85MP0005253_abnormal_eye_physiology1.10200901
86MP0000566_synostosis1.08884559
87MP0010094_abnormal_chromosome_stability1.08344301
88MP0000049_abnormal_middle_ear1.08199675
89MP0004381_abnormal_hair_follicle1.06998062
90MP0000653_abnormal_sex_gland1.05472796
91MP0001845_abnormal_inflammatory_respons1.04508649
92MP0001853_heart_inflammation1.04314323
93MP0001819_abnormal_immune_cell1.03794451
94MP0002452_abnormal_antigen_presenting1.03582438
95MP0003937_abnormal_limbs/digits/tail_de1.02887246
96MP0009333_abnormal_splenocyte_physiolog1.02322861
97MP0006036_abnormal_mitochondrial_physio0.99657179
98MP0000778_abnormal_nervous_system0.99310927
99MP0001145_abnormal_male_reproductive0.98933622
100MP0001286_abnormal_eye_development0.98887198
101MP0004270_analgesia0.98644542
102MP0002420_abnormal_adaptive_immunity0.98618292
103MP0009780_abnormal_chondrocyte_physiolo0.97928002
104MP0003252_abnormal_bile_duct0.97735428
105MP0003315_abnormal_perineum_morphology0.94957604
106MP0001501_abnormal_sleep_pattern0.93991307
107MP0005171_absent_coat_pigmentation0.93770333
108MP0001440_abnormal_grooming_behavior0.93592867
109MP0002736_abnormal_nociception_after0.93330797
110MP0003183_abnormal_peptide_metabolism0.92790470
111MP0003656_abnormal_erythrocyte_physiolo0.92060932
112MP0004043_abnormal_pH_regulation0.91098768
113MP0004133_heterotaxia0.90785232
114MP0003119_abnormal_digestive_system0.90320675
115MP0001542_abnormal_bone_strength0.90312508
116MP0009763_increased_sensitivity_to0.90121591
117MP0001533_abnormal_skeleton_physiology0.89750851
118MP0004147_increased_porphyrin_level0.89531228
119MP0001790_abnormal_immune_system0.87905925
120MP0005387_immune_system_phenotype0.87905925
121MP0000609_abnormal_liver_physiology0.87031080
122MP0004142_abnormal_muscle_tone0.86292328
123MP0009379_abnormal_foot_pigmentation0.85660169
124MP0000427_abnormal_hair_cycle0.85551005
125MP0003567_abnormal_fetal_cardiomyocyte0.84766825
126MP0002735_abnormal_chemical_nociception0.84526113
127MP0001485_abnormal_pinna_reflex0.84362501
128MP0003646_muscle_fatigue0.84131061
129MP0001666_abnormal_nutrient_absorption0.83383068
130MP0005376_homeostasis/metabolism_phenot0.82980155
131MP0002734_abnormal_mechanical_nocicepti0.82762216
132MP0003111_abnormal_nucleus_morphology0.82741524
133MP0005535_abnormal_body_temperature0.81901189
134MP0005636_abnormal_mineral_homeostasis0.81711530
135MP0002084_abnormal_developmental_patter0.81149633
136MP0005646_abnormal_pituitary_gland0.81059768
137MP0000372_irregular_coat_pigmentation0.80464047
138MP0005391_vision/eye_phenotype0.80082377
139MP0002118_abnormal_lipid_homeostasis0.79096988
140MP0003938_abnormal_ear_development0.78758606
141MP0001905_abnormal_dopamine_level0.78062498
142MP0003077_abnormal_cell_cycle0.78036975
143MP0003698_abnormal_male_reproductive0.77414639
144MP0002697_abnormal_eye_size0.77063107
145MP0001177_atelectasis0.77055895
146MP0004215_abnormal_myocardial_fiber0.76980850
147MP0002161_abnormal_fertility/fecundity0.75614680
148MP0002138_abnormal_hepatobiliary_system0.75282642
149MP0005319_abnormal_enzyme/_coenzyme0.74625625
150MP0002837_dystrophic_cardiac_calcinosis0.72962468
151MP0001968_abnormal_touch/_nociception0.72594208
152MP0003786_premature_aging0.72130868
153MP0005464_abnormal_platelet_physiology0.71893831
154MP0002398_abnormal_bone_marrow0.71650614
155MP0003699_abnormal_female_reproductive0.70904102
156MP0001730_embryonic_growth_arrest0.70751226
157MP0002085_abnormal_embryonic_tissue0.70333283
158MP0005451_abnormal_body_composition0.69696655
159MP0001346_abnormal_lacrimal_gland0.69629835
160MP0009046_muscle_twitch0.68637062
161MP0003755_abnormal_palate_morphology0.67891310
162MP0003868_abnormal_feces_composition0.67874524
163MP0005195_abnormal_posterior_eye0.67563511

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.29784228
2Acute encephalopathy (HP:0006846)3.89225913
3Supernumerary spleens (HP:0009799)3.88837030
4Prolonged partial thromboplastin time (HP:0003645)3.71418238
5Abnormal mitochondria in muscle tissue (HP:0008316)3.63450953
6Progressive macrocephaly (HP:0004481)3.51911280
7Reticulocytopenia (HP:0001896)3.49853744
8Mitochondrial inheritance (HP:0001427)3.46493619
9Abnormality of the labia minora (HP:0012880)3.45515517
10Increased hepatocellular lipid droplets (HP:0006565)3.44423418
11Increased CSF lactate (HP:0002490)3.20216752
12Lipid accumulation in hepatocytes (HP:0006561)3.18506958
13Macrocytic anemia (HP:0001972)3.11922049
14Cerebral edema (HP:0002181)3.06158191
153-Methylglutaconic aciduria (HP:0003535)3.01808943
16Hypobetalipoproteinemia (HP:0003563)2.94393724
17Septo-optic dysplasia (HP:0100842)2.93088120
18Renal Fanconi syndrome (HP:0001994)2.92995229
19Birth length less than 3rd percentile (HP:0003561)2.81244178
20Colon cancer (HP:0003003)2.71399880
21Abnormality of T cell number (HP:0011839)2.68333267
22Conjugated hyperbilirubinemia (HP:0002908)2.62121790
23Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.61062066
24T lymphocytopenia (HP:0005403)2.60722882
25Volvulus (HP:0002580)2.60225112
26Abnormal lung lobation (HP:0002101)2.59995559
27Poor head control (HP:0002421)2.59732300
28Abnormality of pyrimidine metabolism (HP:0004353)2.58633125
29Exertional dyspnea (HP:0002875)2.55877161
30Oligodactyly (hands) (HP:0001180)2.55529000
31Prolonged neonatal jaundice (HP:0006579)2.52669041
32Increased IgM level (HP:0003496)2.50066537
33Abnormality of cells of the erythroid lineage (HP:0012130)2.49831623
34Abnormality of aromatic amino acid family metabolism (HP:0004338)2.48690813
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.46658714
36Parakeratosis (HP:0001036)2.41002061
37Abdominal situs inversus (HP:0003363)2.40049846
38Abnormality of abdominal situs (HP:0011620)2.40049846
39Generalized hypopigmentation of hair (HP:0011358)2.34724964
40Joint hemorrhage (HP:0005261)2.34295580
41Optic disc pallor (HP:0000543)2.33973759
42Increased serum pyruvate (HP:0003542)2.31825547
43Abnormality of glycolysis (HP:0004366)2.31825547
44Median cleft lip (HP:0000161)2.30315082
45Absent septum pellucidum (HP:0001331)2.29882647
46Meckel diverticulum (HP:0002245)2.29392594
47Increased serum lactate (HP:0002151)2.27882935
48Methylmalonic acidemia (HP:0002912)2.27446939
49Abnormality of aspartate family amino acid metabolism (HP:0010899)2.25436747
50Lethargy (HP:0001254)2.25217752
51Recurrent gram-negative bacterial infections (HP:0005420)2.24913195
52Abnormality of chromosome stability (HP:0003220)2.24621981
53Abnormality of the ileum (HP:0001549)2.24011316
54Severe combined immunodeficiency (HP:0004430)2.23700644
55Spastic paraparesis (HP:0002313)2.23534742
56Proximal tubulopathy (HP:0000114)2.22792668
57Spontaneous abortion (HP:0005268)2.22766299
58Medial flaring of the eyebrow (HP:0010747)2.22646790
59Myokymia (HP:0002411)2.21205492
60Lactic acidosis (HP:0003128)2.20417610
61Respiratory difficulties (HP:0002880)2.19538675
62Hypoglycemic coma (HP:0001325)2.18234731
63Fat malabsorption (HP:0002630)2.18187011
64Combined immunodeficiency (HP:0005387)2.17980599
65Abnormality of monocarboxylic acid metabolism (HP:0010996)2.17480157
66Molar tooth sign on MRI (HP:0002419)2.17325956
67Abnormality of midbrain morphology (HP:0002418)2.17325956
68Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.16544246
69Abnormality of the anterior horn cell (HP:0006802)2.16083955
70Degeneration of anterior horn cells (HP:0002398)2.16083955
71Intestinal atresia (HP:0011100)2.15800605
72Abnormal number of erythroid precursors (HP:0012131)2.14906980
73Aplasia/Hypoplasia of the tongue (HP:0010295)2.14661446
74Abnormality of renal resorption (HP:0011038)2.14332037
75Vacuolated lymphocytes (HP:0001922)2.14129369
76Retrobulbar optic neuritis (HP:0100654)2.13900238
77Optic neuritis (HP:0100653)2.13900238
78Oligodactyly (HP:0012165)2.09377962
79Pancreatic fibrosis (HP:0100732)2.07984867
80Premature graying of hair (HP:0002216)2.06891992
81Hyperglycinemia (HP:0002154)2.06820185
82Chromosomal breakage induced by crosslinking agents (HP:0003221)2.06401740
83Intrahepatic cholestasis (HP:0001406)2.06138062
84Anorexia (HP:0002039)2.05941670
85Megaloblastic anemia (HP:0001889)2.05641204
86Systemic lupus erythematosus (HP:0002725)2.05559775
87Hepatocellular necrosis (HP:0001404)2.05382505
88Hepatic necrosis (HP:0002605)2.04636318
89Abnormality of methionine metabolism (HP:0010901)2.03351703
90Exercise intolerance (HP:0003546)2.02901661
91Steatorrhea (HP:0002570)2.01203660
92Aplasia/Hypoplasia of the uvula (HP:0010293)1.99698350
93Increased intramyocellular lipid droplets (HP:0012240)1.99647146
94Leukodystrophy (HP:0002415)1.98236392
95Sensory axonal neuropathy (HP:0003390)1.96900725
96Optic nerve hypoplasia (HP:0000609)1.96203013
97Keratoconjunctivitis sicca (HP:0001097)1.95729933
98Chromsome breakage (HP:0040012)1.95532479
99Absent thumb (HP:0009777)1.95337486
100Congenital ichthyosiform erythroderma (HP:0007431)1.94718882
101Elevated erythrocyte sedimentation rate (HP:0003565)1.94460815
102Glycosuria (HP:0003076)1.93795490
103Abnormality of urine glucose concentration (HP:0011016)1.93795490
104Pancreatic cysts (HP:0001737)1.93475435
105Purpura (HP:0000979)1.93102478
106Abnormality of T cells (HP:0002843)1.92787305
107Triphalangeal thumb (HP:0001199)1.92674487
108Short tibia (HP:0005736)1.91093164
109Hyperventilation (HP:0002883)1.90129582
110Abnormality of the preputium (HP:0100587)1.90071156
111Facial hemangioma (HP:0000329)1.89842276
112Abnormality of the septum pellucidum (HP:0007375)1.88681538
113Nephronophthisis (HP:0000090)1.87836603
114Gait imbalance (HP:0002141)1.85715311
115Congenital primary aphakia (HP:0007707)1.84779032
116Irregular epiphyses (HP:0010582)1.83831156
117Orchitis (HP:0100796)1.83700226
118Abnormality of serum amino acid levels (HP:0003112)1.82691699
119Renal cortical cysts (HP:0000803)1.82274737
120Hyperphosphaturia (HP:0003109)1.81450834
121Cleft eyelid (HP:0000625)1.81219073
122Prostate neoplasm (HP:0100787)1.81097146
123Fair hair (HP:0002286)1.79771611
124Hypothermia (HP:0002045)1.79395211
125Keratoconjunctivitis (HP:0001096)1.78936908
126Pulmonary infiltrates (HP:0002113)1.78743912
127Abnormal hair whorl (HP:0010721)1.78560379
128Impulsivity (HP:0100710)1.78397032
129Microvesicular hepatic steatosis (HP:0001414)1.78175322
130True hermaphroditism (HP:0010459)1.76894823
131Oral leukoplakia (HP:0002745)1.76338516
132Adrenal hypoplasia (HP:0000835)1.75891513
133Bone marrow hypocellularity (HP:0005528)1.74897944
134Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.74717937
135Hypochromic microcytic anemia (HP:0004840)1.73811919
136Methylmalonic aciduria (HP:0012120)1.73266363
137Respiratory failure (HP:0002878)1.72457959
138Pustule (HP:0200039)1.72396838
139Osteomalacia (HP:0002749)1.70813361
140Thyroiditis (HP:0100646)1.70580763
141Abnormal urine phosphate concentration (HP:0012599)1.70397187
142Stenosis of the external auditory canal (HP:0000402)1.69171218
143Acute hepatic failure (HP:0006554)1.69015220
144Lower limb hyperreflexia (HP:0002395)1.68435640
145Nephrogenic diabetes insipidus (HP:0009806)1.68385765
146Flat capital femoral epiphysis (HP:0003370)1.68276965
147Microglossia (HP:0000171)1.67952957
148Stomatitis (HP:0010280)1.67946888
149Maternal diabetes (HP:0009800)1.67740739
150Gangrene (HP:0100758)1.67740657
151Genital tract atresia (HP:0001827)1.67670716
152Aplasia/Hypoplasia of the tibia (HP:0005772)1.66185927
153Azoospermia (HP:0000027)1.66084286
154Abnormality of vitamin B metabolism (HP:0004340)1.65506795
155Tubulointerstitial nephritis (HP:0001970)1.64812073
156Abnormality of the duodenum (HP:0002246)1.64551391
157Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.64274793
158Decreased activity of mitochondrial respiratory chain (HP:0008972)1.64274793
159Pallor (HP:0000980)1.63930285
160Horseshoe kidney (HP:0000085)1.63554082
161Recurrent bacterial skin infections (HP:0005406)1.63186459
162Duodenal stenosis (HP:0100867)1.62621661
163Small intestinal stenosis (HP:0012848)1.62621661
164Gastrointestinal atresia (HP:0002589)1.62391131
165Abnormal spermatogenesis (HP:0008669)1.61723917
166Nephroblastoma (Wilms tumor) (HP:0002667)1.61401364
167Increased circulating renin level (HP:0000848)1.61223259
168Duplication of thumb phalanx (HP:0009942)1.60967417

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK3.69265616
2MST43.69039157
3SRPK13.18397401
4MAP3K122.99505326
5SIK32.80781900
6VRK22.74036497
7TTK2.57889650
8BMPR22.52746158
9NEK12.51573877
10EIF2AK12.46916133
11MAP3K142.41162493
12MAP3K92.37808924
13TSSK61.96653597
14CASK1.93604222
15RIPK41.92851794
16TXK1.91583769
17ARAF1.89281136
18PLK21.88004294
19TRIM281.84352217
20NME11.83897111
21PLK41.81583591
22CDK191.80110827
23NME21.78329473
24STK161.71967759
25PIM21.69330194
26AKT31.64739481
27WNK31.62666707
28TNIK1.61408622
29BUB11.59982375
30NEK91.59696364
31EIF2AK31.51565002
32ERBB31.48300913
33VRK11.45456954
34MKNK21.45146572
35PLK31.45072475
36MAP2K71.41439717
37IRAK41.37628249
38TAF11.37575519
39NEK21.34902351
40PASK1.33229483
41NUAK11.25161040
42BRAF1.24462042
43WEE11.23829455
44GRK11.23227042
45EIF2AK21.23060528
46STK31.22048013
47INSRR1.21510203
48BCR1.19067068
49STK391.16011486
50PINK11.15537348
51ADRBK21.12576589
52BRSK21.11950673
53IKBKE1.11595901
54MAP4K21.10100287
55IRAK31.08474673
56MAP3K41.08142371
57GRK61.06134603
58CDC70.98983119
59PIK3CG0.97757761
60TBK10.94863942
61MARK30.90242498
62EPHA40.87356062
63ZAK0.87204895
64ABL20.86716584
65ERBB40.85950400
66PRKCI0.83871985
67JAK10.81910747
68CHEK20.81276050
69PHKG10.81229760
70PHKG20.81229760
71DYRK20.81065850
72OXSR10.79398698
73CHUK0.79280245
74ATR0.79075355
75TESK20.75074592
76MAP3K130.74782470
77OBSCN0.72992778
78PLK10.72768850
79NTRK20.71419828
80LIMK10.71242397
81JAK30.71046088
82CSNK1E0.70682721
83NLK0.70512327
84ATM0.70166178
85MAP3K50.70148967
86GRK70.70082063
87CDK90.69853235
88PRKCQ0.68344011
89CSNK1G10.68252858
90GRK50.67193321
91ACVR1B0.66765455
92NEK60.66687753
93MKNK10.65779444
94STK40.65731431
95TEC0.64434528
96CHEK10.64056054
97IKBKB0.62412543
98NTRK30.60872722
99PNCK0.60651872
100CDK80.58415020
101RAF10.57637177
102CSNK1G30.55522038
103DMPK0.54525414
104EPHB20.54224147
105CSNK2A10.53975832
106TGFBR10.52854187
107TIE10.52287514
108CDK70.52239923
109WNK40.51867516
110FGFR20.51705998
111ITK0.51251525
112STK38L0.49954693
113MET0.49039133
114BRSK10.48282005
115BLK0.48161282
116SYK0.47679618
117PRKCG0.47587955
118TESK10.46580831
119AURKA0.46407492
120PIM10.46277383
121MAPK130.45342306
122DYRK1A0.44571221
123CDK10.42620918
124BMPR1B0.42281771
125PIK3CA0.42250045
126RPS6KB10.42168566
127STK240.41371093
128CDK11A0.40940659
129CDK20.40782016
130CDK30.40370586
131MAP2K40.39906722
132MINK10.39388122
133CCNB10.38779408
134PRKCE0.38491956
135FRK0.36424992
136CSNK2A20.36421836
137PRKG10.36111087
138MST1R0.36019998
139PRKACA0.35573699
140AURKB0.35000658
141YES10.34754058
142CSNK1G20.34159125
143TYK20.34009144
144PRKCD0.33885362
145LYN0.32570675
146PAK30.32241386
147CAMK2A0.31527965

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.08347990
2Ribosome_Homo sapiens_hsa030103.51036672
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.98097222
4Oxidative phosphorylation_Homo sapiens_hsa001902.94565282
5RNA polymerase_Homo sapiens_hsa030202.92180462
6Graft-versus-host disease_Homo sapiens_hsa053322.90533795
7Protein export_Homo sapiens_hsa030602.87056474
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.12985308
9Parkinsons disease_Homo sapiens_hsa050122.07042067
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.97448011
11Allograft rejection_Homo sapiens_hsa053301.74696366
12Vitamin B6 metabolism_Homo sapiens_hsa007501.73937679
13Pyrimidine metabolism_Homo sapiens_hsa002401.72309916
14Non-homologous end-joining_Homo sapiens_hsa034501.72162649
15Alzheimers disease_Homo sapiens_hsa050101.71052215
16Type I diabetes mellitus_Homo sapiens_hsa049401.68884564
17Primary bile acid biosynthesis_Homo sapiens_hsa001201.67386370
18Steroid biosynthesis_Homo sapiens_hsa001001.64862958
19Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.64134324
20Huntingtons disease_Homo sapiens_hsa050161.62727032
21Propanoate metabolism_Homo sapiens_hsa006401.62536166
22Sulfur metabolism_Homo sapiens_hsa009201.61630499
23Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.58902816
24Folate biosynthesis_Homo sapiens_hsa007901.54713245
25Homologous recombination_Homo sapiens_hsa034401.53549741
26Rheumatoid arthritis_Homo sapiens_hsa053231.52667186
27Cell cycle_Homo sapiens_hsa041101.50008118
28Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.49706581
29Collecting duct acid secretion_Homo sapiens_hsa049661.48431455
30Cardiac muscle contraction_Homo sapiens_hsa042601.46839245
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.45774018
32Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.44085800
33Pyruvate metabolism_Homo sapiens_hsa006201.34694087
34Staphylococcus aureus infection_Homo sapiens_hsa051501.31178740
35Tryptophan metabolism_Homo sapiens_hsa003801.27450574
36Basal transcription factors_Homo sapiens_hsa030221.27009147
37Maturity onset diabetes of the young_Homo sapiens_hsa049501.24854910
38Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.23122575
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.22108274
40Peroxisome_Homo sapiens_hsa041461.21714178
41Histidine metabolism_Homo sapiens_hsa003401.21077522
42Oocyte meiosis_Homo sapiens_hsa041141.18523269
43Complement and coagulation cascades_Homo sapiens_hsa046101.18128311
44Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.17339267
45SNARE interactions in vesicular transport_Homo sapiens_hsa041301.14095659
46Intestinal immune network for IgA production_Homo sapiens_hsa046721.12874660
47Drug metabolism - other enzymes_Homo sapiens_hsa009831.12640380
48RNA degradation_Homo sapiens_hsa030181.09919154
49Autoimmune thyroid disease_Homo sapiens_hsa053201.08427788
50Pentose and glucuronate interconversions_Homo sapiens_hsa000401.07347245
51Phenylalanine metabolism_Homo sapiens_hsa003601.01975319
52Chemical carcinogenesis_Homo sapiens_hsa052041.01179278
53Tyrosine metabolism_Homo sapiens_hsa003500.98764479
54Sulfur relay system_Homo sapiens_hsa041220.97592432
55DNA replication_Homo sapiens_hsa030300.96958215
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96127804
57Spliceosome_Homo sapiens_hsa030400.95940010
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95762883
59Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.95618254
60Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.94929696
61Retinol metabolism_Homo sapiens_hsa008300.94202714
62Purine metabolism_Homo sapiens_hsa002300.93860802
63RNA transport_Homo sapiens_hsa030130.93530421
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.93066280
65Mismatch repair_Homo sapiens_hsa034300.92600662
66Vibrio cholerae infection_Homo sapiens_hsa051100.91193666
672-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90013547
68Phototransduction_Homo sapiens_hsa047440.87053543
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.86884262
70Nucleotide excision repair_Homo sapiens_hsa034200.85910476
71Fanconi anemia pathway_Homo sapiens_hsa034600.83022279
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.81694979
73Glutathione metabolism_Homo sapiens_hsa004800.80044455
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.79131234
75Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.78267439
76beta-Alanine metabolism_Homo sapiens_hsa004100.77953549
77Biosynthesis of amino acids_Homo sapiens_hsa012300.74376019
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73760299
79NOD-like receptor signaling pathway_Homo sapiens_hsa046210.73666631
80Carbon metabolism_Homo sapiens_hsa012000.72913582
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72809056
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.72765711
83Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71691688
84Influenza A_Homo sapiens_hsa051640.71643347
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71605138
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.71174277
87Vitamin digestion and absorption_Homo sapiens_hsa049770.71133242
88Herpes simplex infection_Homo sapiens_hsa051680.70327247
89Metabolic pathways_Homo sapiens_hsa011000.69514034
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69031561
91Selenocompound metabolism_Homo sapiens_hsa004500.68331299
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.67383763
93mRNA surveillance pathway_Homo sapiens_hsa030150.67165820
94Fatty acid elongation_Homo sapiens_hsa000620.67045750
95Fatty acid degradation_Homo sapiens_hsa000710.63654679
96Prion diseases_Homo sapiens_hsa050200.63370060
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63365432
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.62596710
99Base excision repair_Homo sapiens_hsa034100.62536311
100Olfactory transduction_Homo sapiens_hsa047400.61618872
101Measles_Homo sapiens_hsa051620.61175365
102Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60307968
103Steroid hormone biosynthesis_Homo sapiens_hsa001400.60063685
104One carbon pool by folate_Homo sapiens_hsa006700.59563148
105Regulation of autophagy_Homo sapiens_hsa041400.59158831
106Circadian rhythm_Homo sapiens_hsa047100.58467026
107African trypanosomiasis_Homo sapiens_hsa051430.58435817
108Linoleic acid metabolism_Homo sapiens_hsa005910.58108494
109Arginine and proline metabolism_Homo sapiens_hsa003300.58063445
110Legionellosis_Homo sapiens_hsa051340.57620276
111Primary immunodeficiency_Homo sapiens_hsa053400.56494253
112p53 signaling pathway_Homo sapiens_hsa041150.56430982
113Hedgehog signaling pathway_Homo sapiens_hsa043400.55773351
114Phagosome_Homo sapiens_hsa041450.55315528
115Butanoate metabolism_Homo sapiens_hsa006500.54900490
116Antigen processing and presentation_Homo sapiens_hsa046120.54423998
117Nicotine addiction_Homo sapiens_hsa050330.54342064
118Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53677555
119Fatty acid metabolism_Homo sapiens_hsa012120.51759729
120Arginine biosynthesis_Homo sapiens_hsa002200.51345653
121Epstein-Barr virus infection_Homo sapiens_hsa051690.49255869
122Cyanoamino acid metabolism_Homo sapiens_hsa004600.47717601
123Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.47173989
124Caffeine metabolism_Homo sapiens_hsa002320.46385457
125Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.46194251
126Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.44381456
127Asthma_Homo sapiens_hsa053100.43318936
128Fat digestion and absorption_Homo sapiens_hsa049750.42753703
129NF-kappa B signaling pathway_Homo sapiens_hsa040640.42700444
130Insulin secretion_Homo sapiens_hsa049110.39396864
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39269793
132Basal cell carcinoma_Homo sapiens_hsa052170.38459914
133Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34337337
134GABAergic synapse_Homo sapiens_hsa047270.33866024
135Bile secretion_Homo sapiens_hsa049760.33136650
136Wnt signaling pathway_Homo sapiens_hsa043100.32196151
137Synaptic vesicle cycle_Homo sapiens_hsa047210.32089901

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »