CCDC27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.87849067
2epithelial cilium movement (GO:0003351)9.38102089
3spermatid development (GO:0007286)9.20454890
4motile cilium assembly (GO:0044458)9.16966533
5regulation of cilium movement (GO:0003352)8.59421384
6cilium movement (GO:0003341)8.08285877
7sperm capacitation (GO:0048240)7.88776182
8single fertilization (GO:0007338)7.87204882
9male meiosis (GO:0007140)7.78947895
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.41518595
11synaptonemal complex organization (GO:0070193)7.07763390
12synaptonemal complex assembly (GO:0007130)7.00630473
13piRNA metabolic process (GO:0034587)6.96646367
14fertilization (GO:0009566)6.42715267
15organic cation transport (GO:0015695)6.12124277
16spermatogenesis (GO:0007283)6.11332129
17male gamete generation (GO:0048232)6.09042876
18negative regulation of inclusion body assembly (GO:0090084)6.07029213
19microtubule depolymerization (GO:0007019)5.97152400
20gamete generation (GO:0007276)5.61395350
21ventricular system development (GO:0021591)5.52350876
22calcium ion-dependent exocytosis (GO:0017156)5.48500622
23spermatid nucleus differentiation (GO:0007289)5.44971561
24cell recognition (GO:0008037)5.39110639
25cellular process involved in reproduction in multicellular organism (GO:0022412)5.33702352
26microtubule severing (GO:0051013)5.29838216
27regulation of inclusion body assembly (GO:0090083)5.10412212
28germ cell development (GO:0007281)5.09584604
29regulation of microtubule-based movement (GO:0060632)4.99939017
30behavioral response to nicotine (GO:0035095)4.99548562
31regulation of acrosome reaction (GO:0060046)4.96311240
32chromosome organization involved in meiosis (GO:0070192)4.84886093
33response to pheromone (GO:0019236)4.81489499
34regulation of female gonad development (GO:2000194)4.73856945
35male meiosis I (GO:0007141)4.64479604
36retinal cone cell development (GO:0046549)4.56423490
37multicellular organismal reproductive process (GO:0048609)4.42829273
38DNA methylation involved in gamete generation (GO:0043046)4.42198824
39meiotic nuclear division (GO:0007126)4.39413940
40protein polyglutamylation (GO:0018095)4.24840602
41glycerol ether metabolic process (GO:0006662)4.10245627
42fucose catabolic process (GO:0019317)3.95022038
43L-fucose metabolic process (GO:0042354)3.95022038
44L-fucose catabolic process (GO:0042355)3.95022038
45regulation of meiosis I (GO:0060631)3.94748665
46left/right pattern formation (GO:0060972)3.91840955
47monoubiquitinated protein deubiquitination (GO:0035520)3.88926309
48chromosome condensation (GO:0030261)3.87695175
49seminiferous tubule development (GO:0072520)3.79105427
50ether metabolic process (GO:0018904)3.78561908
51DNA packaging (GO:0006323)3.67751681
52meiosis I (GO:0007127)3.65927241
53regulation of DNA methylation (GO:0044030)3.65404934
54multicellular organismal development (GO:0007275)3.57234794
55chaperone-mediated protein complex assembly (GO:0051131)3.55241165
56cellular ketone body metabolic process (GO:0046950)3.54235396
57protein localization to cilium (GO:0061512)3.41443345
58genitalia morphogenesis (GO:0035112)3.41381033
59protein K11-linked deubiquitination (GO:0035871)3.38209102
60positive regulation of gastrulation (GO:2000543)3.36099312
61regulation of spindle checkpoint (GO:0090231)3.29055073
62positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.26847627
63detection of light stimulus involved in sensory perception (GO:0050962)3.24893862
64detection of light stimulus involved in visual perception (GO:0050908)3.24893862
65amino-acid betaine transport (GO:0015838)3.19484001
66carnitine transport (GO:0015879)3.19484001
67single strand break repair (GO:0000012)3.13825860
68ketone body metabolic process (GO:1902224)3.12587205
69synapsis (GO:0007129)3.06510732
70carnitine transmembrane transport (GO:1902603)3.05590939
71microtubule polymerization or depolymerization (GO:0031109)3.03869913
72intraciliary transport (GO:0042073)3.03600569
73cAMP catabolic process (GO:0006198)3.02620131
74positive regulation of macrophage activation (GO:0043032)3.00649262
75tryptophan catabolic process (GO:0006569)3.00373181
76indole-containing compound catabolic process (GO:0042436)3.00373181
77indolalkylamine catabolic process (GO:0046218)3.00373181
78nonmotile primary cilium assembly (GO:0035058)3.00222995
79DNA deamination (GO:0045006)2.99507930
80positive regulation of meiosis (GO:0045836)2.99190879
81indolalkylamine metabolic process (GO:0006586)2.98012017
82mitochondrial respiratory chain complex I assembly (GO:0032981)2.97496306
83NADH dehydrogenase complex assembly (GO:0010257)2.97496306
84mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.97496306
85cilium organization (GO:0044782)2.95723087
86meiotic cell cycle (GO:0051321)2.95716170
87microtubule-based movement (GO:0007018)2.93129611
88centriole assembly (GO:0098534)2.92922175
89negative regulation of organelle assembly (GO:1902116)2.90440423
90detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.89157419
91primary amino compound metabolic process (GO:1901160)2.87405870
92cellular component assembly involved in morphogenesis (GO:0010927)2.85363276
93somite rostral/caudal axis specification (GO:0032525)2.83899225
94cilium assembly (GO:0042384)2.83396683
95glycine transport (GO:0015816)2.82926202
96negative regulation of transcription regulatory region DNA binding (GO:2000678)2.82209771
97positive regulation of meiotic cell cycle (GO:0051446)2.81253433
98establishment of protein localization to Golgi (GO:0072600)2.79598999
99positive regulation of histone H3-K4 methylation (GO:0051571)2.78862782
100sexual reproduction (GO:0019953)2.75603227
101protein refolding (GO:0042026)2.75586082
102rRNA methylation (GO:0031167)2.75249101
103cilium morphogenesis (GO:0060271)2.73593817
104peptidyl-glutamic acid modification (GO:0018200)2.73540203
105regulation of calcium ion-dependent exocytosis (GO:0017158)2.72415389
106kynurenine metabolic process (GO:0070189)2.72023138
107protein complex biogenesis (GO:0070271)2.71985748
108oocyte development (GO:0048599)2.70486078
109meiotic cell cycle process (GO:1903046)2.69711523
110calcium ion import (GO:0070509)2.69639951
111nucleus organization (GO:0006997)2.69105083
112axoneme assembly (GO:0035082)2.68613602
113lactate metabolic process (GO:0006089)2.68095913
114glycolytic process (GO:0006096)2.68054396
115behavioral response to ethanol (GO:0048149)2.65079069
116cyclic nucleotide catabolic process (GO:0009214)2.64246281
117photoreceptor cell development (GO:0042461)2.64067798
118tryptophan metabolic process (GO:0006568)2.62903856
119polyol catabolic process (GO:0046174)2.61822974
120protein targeting to Golgi (GO:0000042)2.61358450
121alditol metabolic process (GO:0019400)2.61060931
122gamma-aminobutyric acid transport (GO:0015812)2.60525750
123neuronal action potential (GO:0019228)2.60012657
124neuron fate determination (GO:0048664)2.59688358
125centriole replication (GO:0007099)2.59381335
126regulation of action potential (GO:0098900)2.58913854
127gene silencing by RNA (GO:0031047)2.58182953
128platelet dense granule organization (GO:0060155)2.58050638
129nucleoside diphosphate phosphorylation (GO:0006165)2.57015726
130rRNA modification (GO:0000154)2.55425943
131regulation of centriole replication (GO:0046599)2.52863809
132negative regulation of telomere maintenance (GO:0032205)2.52750782
133water-soluble vitamin biosynthetic process (GO:0042364)2.52379393
134mitochondrial respiratory chain complex assembly (GO:0033108)2.50530477
135female gamete generation (GO:0007292)2.49258504
136reciprocal meiotic recombination (GO:0007131)2.45917432
137reciprocal DNA recombination (GO:0035825)2.45917432
138RNA destabilization (GO:0050779)2.44451669
139indole-containing compound metabolic process (GO:0042430)2.43895744
140interferon-gamma secretion (GO:0072643)2.42752833
141single-organism membrane fusion (GO:0044801)2.42607374
142mitotic sister chromatid cohesion (GO:0007064)2.37543276
143RNA localization (GO:0006403)2.36747183
144peptidyl-lysine dimethylation (GO:0018027)2.35728535
145membrane depolarization during action potential (GO:0086010)2.35381541
146regulation of response to osmotic stress (GO:0047484)2.33364423
147cell wall macromolecule catabolic process (GO:0016998)14.6019825
148cell wall macromolecule metabolic process (GO:0044036)14.6019825
149fusion of sperm to egg plasma membrane (GO:0007342)14.3694869
150acrosome assembly (GO:0001675)13.0969105
151sperm motility (GO:0030317)12.8854631
152multicellular organism reproduction (GO:0032504)12.5569437
153sperm-egg recognition (GO:0035036)12.2740668
154acrosome reaction (GO:0007340)11.3719261
155cilium or flagellum-dependent cell motility (GO:0001539)11.3177744
156cell-cell recognition (GO:0009988)10.9863023
157plasma membrane fusion (GO:0045026)10.9586102
158binding of sperm to zona pellucida (GO:0007339)10.5220807
159reproduction (GO:0000003)10.3789634

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.70833999
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.10206238
3EZH2_22144423_ChIP-Seq_EOC_Human3.45454529
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.42190093
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.91293568
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.75348504
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.61120166
8GBX2_23144817_ChIP-Seq_PC3_Human2.57906485
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.53261456
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.30176043
11VDR_22108803_ChIP-Seq_LS180_Human2.24928657
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.22555119
13STAT6_21828071_ChIP-Seq_BEAS2B_Human2.22500249
14PCGF2_27294783_Chip-Seq_ESCs_Mouse2.19803650
15CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06100256
16CBX2_27304074_Chip-Seq_ESCs_Mouse2.05810011
17FUS_26573619_Chip-Seq_HEK293_Human2.04166513
18CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.03980538
19ZNF274_21170338_ChIP-Seq_K562_Hela2.03036891
20KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse2.02998487
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.97250405
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.95813657
23TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.87308927
24P300_19829295_ChIP-Seq_ESCs_Human1.83301888
25RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.80421618
26GATA1_26923725_Chip-Seq_HPCs_Mouse1.80258590
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.74892194
28EWS_26573619_Chip-Seq_HEK293_Human1.73726868
29KAP1_22055183_ChIP-Seq_ESCs_Mouse1.73340185
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.73135376
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.71666421
32ER_23166858_ChIP-Seq_MCF-7_Human1.69996972
33STAT1_17558387_ChIP-Seq_HELA_Human1.69363089
34POU3F2_20337985_ChIP-ChIP_501MEL_Human1.68827181
35HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.66566552
36ELK4_26923725_Chip-Seq_MESODERM_Mouse1.64738563
37UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.63593566
38GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.63470194
39HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60019175
40KDM2B_26808549_Chip-Seq_REH_Human1.59444417
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58985263
42FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58597349
43AR_25329375_ChIP-Seq_VCAP_Human1.57178137
44ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.56948385
45MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.55937581
46TAL1_26923725_Chip-Seq_HPCs_Mouse1.54149644
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.52679754
48CBP_20019798_ChIP-Seq_JUKART_Human1.51572916
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51572916
50IGF1R_20145208_ChIP-Seq_DFB_Human1.51521457
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.50229760
52* TP53_22573176_ChIP-Seq_HFKS_Human1.48811556
53GATA3_21867929_ChIP-Seq_CD8_Mouse1.48175575
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46416628
55WDR5_24793694_ChIP-Seq_LNCAP_Human1.46076164
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.45477239
57FLI1_21867929_ChIP-Seq_TH2_Mouse1.45455376
58STAT3_23295773_ChIP-Seq_U87_Human1.45446795
59SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45320279
60TCF4_23295773_ChIP-Seq_U87_Human1.44399648
61IRF1_19129219_ChIP-ChIP_H3396_Human1.43289742
62SOX2_22085726_ChIP-Seq_NPCs_Mouse1.43079438
63SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42850695
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.42816332
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.42537136
66CTBP2_25329375_ChIP-Seq_LNCAP_Human1.41995815
67SMAD4_21799915_ChIP-Seq_A2780_Human1.40931605
68E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40456983
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.39018942
70GATA3_21867929_ChIP-Seq_TH1_Mouse1.36178011
71SMAD4_21741376_ChIP-Seq_EPCs_Human1.36070879
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.35946132
73LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.35383900
74RNF2_27304074_Chip-Seq_NSC_Mouse1.34786068
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33903531
76GATA3_21878914_ChIP-Seq_MCF-7_Human1.33091906
77RUNX1_26923725_Chip-Seq_HPCs_Mouse1.32303808
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.32143195
79FOXA1_27270436_Chip-Seq_PROSTATE_Human1.31996425
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.31996425
81SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.30131019
82OCT4_18555785_Chip-Seq_ESCs_Mouse1.29567998
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29503998
84CRX_20693478_ChIP-Seq_RETINA_Mouse1.29299867
85SMAD3_21741376_ChIP-Seq_EPCs_Human1.28727057
86SOX2_19829295_ChIP-Seq_ESCs_Human1.28389151
87NANOG_19829295_ChIP-Seq_ESCs_Human1.28389151
88* RUNX2_22187159_ChIP-Seq_PCA_Human1.28028078
89BCAT_22108803_ChIP-Seq_LS180_Human1.26396408
90MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25483245
91GF1_26923725_Chip-Seq_HPCs_Mouse1.25190980
92REST_21632747_ChIP-Seq_MESCs_Mouse1.24960113
93NANOG_20526341_ChIP-Seq_ESCs_Human1.24568514
94PRDM14_20953172_ChIP-Seq_ESCs_Human1.24116143
95TP63_19390658_ChIP-ChIP_HaCaT_Human1.23660491
96PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.23173196
97EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.22005378
98P53_22387025_ChIP-Seq_ESCs_Mouse1.21422115
99CMYC_18555785_Chip-Seq_ESCs_Mouse1.20016496
100NCOR_22424771_ChIP-Seq_293T_Human1.20000476
101ESRRB_18555785_Chip-Seq_ESCs_Mouse1.19576753
102KLF4_18555785_Chip-Seq_ESCs_Mouse1.19012177
103ETV2_25802403_ChIP-Seq_MESCs_Mouse1.18577393
104EZH2_27294783_Chip-Seq_NPCs_Mouse1.18443178
105P53_21459846_ChIP-Seq_SAOS-2_Human1.18245211
106P300_18555785_Chip-Seq_ESCs_Mouse1.18210701
107TCF4_22108803_ChIP-Seq_LS180_Human1.17212783
108CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16786822
109KLF5_20875108_ChIP-Seq_MESCs_Mouse1.16545041
110NR3C1_21868756_ChIP-Seq_MCF10A_Human1.15987590
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15943368
112FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15909902
113EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.15816422
114SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.15815828
115AUTS2_25519132_ChIP-Seq_293T-REX_Human1.14755308
116CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13377320
117SUZ12_18555785_Chip-Seq_ESCs_Mouse1.13262083
118SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.12670172
119OCT4_21477851_ChIP-Seq_ESCs_Mouse1.12421647
120HOXB7_26014856_ChIP-Seq_BT474_Human1.11788195
121SPI1_26923725_Chip-Seq_HPCs_Mouse1.11316723
122* TAF2_19829295_ChIP-Seq_ESCs_Human1.10933376
123CTCF_18555785_Chip-Seq_ESCs_Mouse1.10698540
124EZH2_27304074_Chip-Seq_ESCs_Mouse1.10297871
125* MYC_18940864_ChIP-ChIP_HL60_Human1.09989453
126FOXA1_21572438_ChIP-Seq_LNCaP_Human1.09799671
127TAF15_26573619_Chip-Seq_HEK293_Human1.08068267
128AR_20517297_ChIP-Seq_VCAP_Human1.07916301
129RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07653508
130EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.06104152
131POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05897067
132TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05897067
133STAT3_18555785_Chip-Seq_ESCs_Mouse1.05719353
134DROSHA_22980978_ChIP-Seq_HELA_Human1.05476251
135MYC_19829295_ChIP-Seq_ESCs_Human1.05313191
136FOXH1_21741376_ChIP-Seq_EPCs_Human1.04361559
137SOX2_18555785_Chip-Seq_ESCs_Mouse1.04069525
138CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03956660
139MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.03744858
140EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.02862195
141ERA_21632823_ChIP-Seq_H3396_Human1.02117448
142PIAS1_25552417_ChIP-Seq_VCAP_Human1.00293831
143PU1_27457419_Chip-Seq_LIVER_Mouse0.99969028
144RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99842161
145GABP_17652178_ChIP-ChIP_JURKAT_Human0.99450435
146RUNX1_27457419_Chip-Seq_LIVER_Mouse0.99274549
147CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99255118
148SMAD3_21741376_ChIP-Seq_ESCs_Human0.98735791
149ESET_19884257_ChIP-Seq_ESCs_Mouse0.98529630
150SMAD1_18555785_Chip-Seq_ESCs_Mouse0.98322650
151EST1_17652178_ChIP-ChIP_JURKAT_Human0.97929141
152GATA1_19941827_ChIP-Seq_MEL86_Mouse0.97702588
153PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.97681819
154RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97654766
155CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97313733
156RARA_24833708_ChIP-Seq_LIVER_Mouse0.97226275
157PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96671976
158AR_21572438_ChIP-Seq_LNCaP_Human0.95770994
159CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95737586
160CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.95577862
161GF1B_26923725_Chip-Seq_HPCs_Mouse0.95178685
162* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.94813928
163E2F1_18555785_Chip-Seq_ESCs_Mouse0.94701786
164* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.93556113
165TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.93517010
166LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.93435925
167NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.92921599
168EZH2_27294783_Chip-Seq_ESCs_Mouse0.92379335
169EED_16625203_ChIP-ChIP_MESCs_Mouse0.92218016
170REST_18959480_ChIP-ChIP_MESCs_Mouse0.91984777
171NMYC_18555785_Chip-Seq_ESCs_Mouse0.91663965
172STAT3_18555785_ChIP-Seq_MESCs_Mouse0.91193211
173ERG_20517297_ChIP-Seq_VCAP_Human0.91179962

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.06802735
2MP0001929_abnormal_gametogenesis5.45458107
3MP0008877_abnormal_DNA_methylation4.30315251
4MP0003718_maternal_effect3.86060537
5MP0006292_abnormal_olfactory_placode3.58946168
6MP0002653_abnormal_ependyma_morphology3.50094851
7MP0002210_abnormal_sex_determination3.42300183
8MP0002161_abnormal_fertility/fecundity3.27559058
9MP0001145_abnormal_male_reproductive2.93943539
10MP0000653_abnormal_sex_gland2.58983284
11MP0005623_abnormal_meninges_morphology2.44021344
12MP0005670_abnormal_white_adipose2.41509327
13MP0003195_calcinosis2.04264695
14MP0003136_yellow_coat_color2.00583148
15MP0009046_muscle_twitch2.00366299
16MP0005410_abnormal_fertilization15.9714760
17MP0004142_abnormal_muscle_tone1.97755535
18MP0008789_abnormal_olfactory_epithelium1.85635982
19MP0005646_abnormal_pituitary_gland1.82786811
20MP0002272_abnormal_nervous_system1.79261146
21MP0002138_abnormal_hepatobiliary_system1.72471301
22MP0000631_abnormal_neuroendocrine_gland1.71073582
23MP0006276_abnormal_autonomic_nervous1.70637108
24MP0009745_abnormal_behavioral_response1.70327049
25MP0001986_abnormal_taste_sensitivity1.64939040
26MP0002735_abnormal_chemical_nociception1.61943631
27MP0005645_abnormal_hypothalamus_physiol1.58942628
28MP0004233_abnormal_muscle_weight1.52768992
29MP0005499_abnormal_olfactory_system1.50681666
30MP0005394_taste/olfaction_phenotype1.50681666
31MP0001486_abnormal_startle_reflex1.49413732
32MP0006072_abnormal_retinal_apoptosis1.48091406
33MP0003880_abnormal_central_pattern1.47052491
34MP0000566_synostosis1.42916222
35MP0001485_abnormal_pinna_reflex1.40752232
36MP0002282_abnormal_trachea_morphology1.40506410
37MP0002638_abnormal_pupillary_reflex1.37020987
38MP0003121_genomic_imprinting1.36566044
39MP0005395_other_phenotype1.36451271
40MP0003646_muscle_fatigue1.32709742
41MP0002160_abnormal_reproductive_system1.30552529
42MP0004885_abnormal_endolymph1.29580827
43MP0000372_irregular_coat_pigmentation1.24733324
44MP0001765_abnormal_ion_homeostasis1.24400298
45MP0001501_abnormal_sleep_pattern1.23558765
46MP0008058_abnormal_DNA_repair1.22278835
47MP0001984_abnormal_olfaction1.22085727
48MP0002733_abnormal_thermal_nociception1.21511967
49MP0002938_white_spotting1.20144036
50MP0005379_endocrine/exocrine_gland_phen1.19880749
51MP0003890_abnormal_embryonic-extraembry1.16286303
52MP0002557_abnormal_social/conspecific_i1.15570170
53MP0002876_abnormal_thyroid_physiology1.12945081
54MP0001529_abnormal_vocalization1.12140595
55MP0002067_abnormal_sensory_capabilities1.11024307
56MP0002163_abnormal_gland_morphology1.10709633
57MP0002064_seizures1.09036563
58MP0001970_abnormal_pain_threshold1.06734262
59MP0003635_abnormal_synaptic_transmissio1.03504867
60MP0001905_abnormal_dopamine_level1.03462933
61MP0003283_abnormal_digestive_organ1.03383547
62MP0005174_abnormal_tail_pigmentation1.03225580
63MP0005647_abnormal_sex_gland1.02175028
64MP0000026_abnormal_inner_ear1.02038260
65MP0002734_abnormal_mechanical_nocicepti1.01788931
66MP0002063_abnormal_learning/memory/cond0.99781966
67MP0001963_abnormal_hearing_physiology0.99595216
68MP0002796_impaired_skin_barrier0.98856585
69MP0005195_abnormal_posterior_eye0.97363302
70MP0000049_abnormal_middle_ear0.96299297
71MP0005084_abnormal_gallbladder_morpholo0.96214338
72MP0003119_abnormal_digestive_system0.96121616
73MP0000778_abnormal_nervous_system0.90428704
74MP0002752_abnormal_somatic_nervous0.90338926
75MP0001919_abnormal_reproductive_system0.86648242
76MP0004924_abnormal_behavior0.86446668
77MP0005386_behavior/neurological_phenoty0.86446668
78MP0005085_abnormal_gallbladder_physiolo0.85246861
79MP0003252_abnormal_bile_duct0.84187287
80MP0002234_abnormal_pharynx_morphology0.77491424
81MP0005636_abnormal_mineral_homeostasis0.71747469
82MP0005389_reproductive_system_phenotype0.70066647
83MP0003950_abnormal_plasma_membrane0.68121470
84MP0002928_abnormal_bile_duct0.67686906
85MP0005377_hearing/vestibular/ear_phenot0.62523695
86MP0003878_abnormal_ear_physiology0.62523695
87MP0002102_abnormal_ear_morphology0.61020013
88MP0003699_abnormal_female_reproductive0.57506001
89MP0010094_abnormal_chromosome_stability0.53794060
90MP0008995_early_reproductive_senescence0.51319543
91MP0005666_abnormal_adipose_tissue0.50346163
92MP0001293_anophthalmia0.49920750
93MP0003656_abnormal_erythrocyte_physiolo0.48897801
94MP0005451_abnormal_body_composition0.48619039
95MP0003115_abnormal_respiratory_system0.48414974
96MP0003011_delayed_dark_adaptation0.48225691
97MP0001324_abnormal_eye_pigmentation0.47966160
98MP0004036_abnormal_muscle_relaxation0.47603856
99MP0008961_abnormal_basal_metabolism0.45081593
100MP0003633_abnormal_nervous_system0.44876631
101MP0000427_abnormal_hair_cycle0.43688621
102MP0008057_abnormal_DNA_replication0.43634984
103MP0005275_abnormal_skin_tensile0.42788152
104MP0002269_muscular_atrophy0.41243455
105MP0001119_abnormal_female_reproductive0.39813888
106MP0003329_amyloid_beta_deposits0.38474379
107MP0002132_abnormal_respiratory_system0.36744485
108MP0005551_abnormal_eye_electrophysiolog0.36476513
109MP0005253_abnormal_eye_physiology0.34468087
110MP0001764_abnormal_homeostasis0.34002935
111MP0000358_abnormal_cell_content/0.33867088
112MP0001545_abnormal_hematopoietic_system0.33580743
113MP0005397_hematopoietic_system_phenotyp0.33580743
114MP0004811_abnormal_neuron_physiology0.33039502
115MP0003631_nervous_system_phenotype0.32882948
116MP0005501_abnormal_skin_physiology0.32425616
117MP0009115_abnormal_fat_cell0.30966724
118MP0002971_abnormal_brown_adipose0.30887770
119MP0000569_abnormal_digit_pigmentation0.30125877
120MP0006036_abnormal_mitochondrial_physio0.29456582
121MP0002736_abnormal_nociception_after0.29184237
122MP0002139_abnormal_hepatobiliary_system0.28825509
123MP0002837_dystrophic_cardiac_calcinosis0.27336473
124MP0010307_abnormal_tumor_latency0.27248545
125MP0003861_abnormal_nervous_system0.26670331
126MP0004133_heterotaxia0.26560333
127MP0009697_abnormal_copulation0.26544202
128MP0002152_abnormal_brain_morphology0.26364034
129MP0005391_vision/eye_phenotype0.26254803
130MP0002572_abnormal_emotion/affect_behav0.26011500
131MP0004019_abnormal_vitamin_homeostasis0.25764971
132MP0008875_abnormal_xenobiotic_pharmacok0.25582185
133MP0004084_abnormal_cardiac_muscle0.23352011
134MP0003786_premature_aging0.22796996
135MP0003787_abnormal_imprinting0.22427628
136MP0005423_abnormal_somatic_nervous0.22311472
137MP0000534_abnormal_ureter_morphology0.21832719
138MP0003111_abnormal_nucleus_morphology0.20474898
139MP0000432_abnormal_head_morphology0.19869395
140MP0004043_abnormal_pH_regulation0.19091020
141MP0003879_abnormal_hair_cell0.18912990
142MP0003942_abnormal_urinary_system0.17860114
143MP0003941_abnormal_skin_development0.17849448
144MP0008872_abnormal_physiological_respon0.17410973
145MP0001968_abnormal_touch/_nociception0.17179795
146MP0002169_no_abnormal_phenotype0.16636040
147MP0002405_respiratory_system_inflammati0.16557494
148MP0005535_abnormal_body_temperature0.16471933
149MP0002873_normal_phenotype0.16445210
150MP0002229_neurodegeneration0.16370095
151MP0004130_abnormal_muscle_cell0.16098533
152MP0004947_skin_inflammation0.16095333
153MP0005375_adipose_tissue_phenotype0.15969219
154MP0001270_distended_abdomen0.15616706
155MP0000313_abnormal_cell_death0.15240763
156MP0000647_abnormal_sebaceous_gland0.15090697
157MP0004742_abnormal_vestibular_system0.14914570
158MP0000604_amyloidosis0.14515373

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.43865825
2Abnormal respiratory motile cilium morphology (HP:0005938)8.55974254
3Abnormal respiratory epithelium morphology (HP:0012253)8.55974254
4Rhinitis (HP:0012384)7.74504746
5Abnormal ciliary motility (HP:0012262)7.71576721
6Chronic bronchitis (HP:0004469)7.19086206
7Nasal polyposis (HP:0100582)6.47467574
8Infertility (HP:0000789)6.29732477
9Abnormality of the nasal mucosa (HP:0000433)5.31256563
10Male infertility (HP:0003251)4.75225102
11Bronchitis (HP:0012387)4.74292711
12Bronchiectasis (HP:0002110)4.56390227
13Nephronophthisis (HP:0000090)4.29374338
14Pancreatic cysts (HP:0001737)4.21702521
15Abnormal spermatogenesis (HP:0008669)3.87724586
16Attenuation of retinal blood vessels (HP:0007843)3.49015116
17Recurrent sinusitis (HP:0011108)3.40591857
18Type II lissencephaly (HP:0007260)3.37377210
19Recurrent otitis media (HP:0000403)3.30344566
20Congenital stationary night blindness (HP:0007642)3.25002124
21Abnormality of the renal medulla (HP:0100957)3.24006789
22Recurrent bronchitis (HP:0002837)3.11097048
23Medial flaring of the eyebrow (HP:0010747)3.05477043
24Abnormal rod and cone electroretinograms (HP:0008323)2.92442000
25Abnormality of midbrain morphology (HP:0002418)2.92374307
26Molar tooth sign on MRI (HP:0002419)2.92374307
27Pendular nystagmus (HP:0012043)2.88066075
28Hypoplasia of the fovea (HP:0007750)2.84107352
29Aplasia/Hypoplasia of the fovea (HP:0008060)2.84107352
30Anterior segment dysgenesis (HP:0007700)2.74274555
31Azoospermia (HP:0000027)2.74135444
32Tubular atrophy (HP:0000092)2.65382395
33Tubulointerstitial nephritis (HP:0001970)2.60235044
34Inability to walk (HP:0002540)2.57872865
35Oligodactyly (hands) (HP:0001180)2.57802104
36Septo-optic dysplasia (HP:0100842)2.53418588
37Severe visual impairment (HP:0001141)2.52358235
38Tongue fasciculations (HP:0001308)2.49473965
39Hyperalaninemia (HP:0003348)2.44687106
40Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.44687106
41Abnormality of alanine metabolism (HP:0010916)2.44687106
42Bony spicule pigmentary retinopathy (HP:0007737)2.43742259
43Tubulointerstitial abnormality (HP:0001969)2.42116357
44Sclerocornea (HP:0000647)2.35194957
45Impulsivity (HP:0100710)2.32099533
46Abnormality of the labia minora (HP:0012880)2.31870360
47Abnormality of the fovea (HP:0000493)2.27800680
48Hyperventilation (HP:0002883)2.26996912
49Gaze-evoked nystagmus (HP:0000640)2.26560579
50Muscle fibrillation (HP:0010546)2.26387580
51Retinal dysplasia (HP:0007973)2.23509356
52Abolished electroretinogram (ERG) (HP:0000550)2.22207486
53Supernumerary spleens (HP:0009799)2.22018538
54Lissencephaly (HP:0001339)2.21357781
55Aplasia/Hypoplasia of the tibia (HP:0005772)2.20405834
56Anencephaly (HP:0002323)2.13897261
57Tubulointerstitial fibrosis (HP:0005576)2.09754204
58Fair hair (HP:0002286)2.06255845
59Progressive cerebellar ataxia (HP:0002073)2.05282721
60Congenital sensorineural hearing impairment (HP:0008527)2.03797281
61Increased corneal curvature (HP:0100692)2.03530686
62Keratoconus (HP:0000563)2.03530686
63Decreased circulating renin level (HP:0003351)2.01909115
64Abnormal gallbladder physiology (HP:0012438)2.01727131
65Cholecystitis (HP:0001082)2.01727131
66Progressive inability to walk (HP:0002505)2.01117494
67Hypophosphatemic rickets (HP:0004912)2.00886417
68Polydipsia (HP:0001959)2.00482287
69Abnormal drinking behavior (HP:0030082)2.00482287
70Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.9386496
71Dynein arm defect of respiratory motile cilia (HP:0012255)12.4032413
72Absent/shortened dynein arms (HP:0200106)12.4032413
73Abdominal situs inversus (HP:0003363)1.99524288
74Abnormality of abdominal situs (HP:0011620)1.99524288
75Decreased central vision (HP:0007663)1.97505433
76Renal cortical cysts (HP:0000803)1.97183246
77Congenital hepatic fibrosis (HP:0002612)1.96991601
78Concave nail (HP:0001598)1.96230264
79Postaxial foot polydactyly (HP:0001830)1.94816256
80Short tibia (HP:0005736)1.94742342
81Congenital, generalized hypertrichosis (HP:0004540)1.92792449
82Abnormality of saccadic eye movements (HP:0000570)1.90327176
83Gait imbalance (HP:0002141)1.88817201
84Gonadotropin excess (HP:0000837)1.88475005
85Stage 5 chronic kidney disease (HP:0003774)1.88243322
86Congenital primary aphakia (HP:0007707)1.87489628
87Microglossia (HP:0000171)1.86882661
88Absent rod-and cone-mediated responses on ERG (HP:0007688)1.85588859
89Pancreatic fibrosis (HP:0100732)1.84430453
90Facial cleft (HP:0002006)1.82270247
91Broad-based gait (HP:0002136)1.81875120
92Chronic sinusitis (HP:0011109)1.79012242
93Short ribs (HP:0000773)1.77764782
94Optic disc pallor (HP:0000543)1.76631278
95J-shaped sella turcica (HP:0002680)1.76001423
96Methylmalonic acidemia (HP:0002912)1.75208860
97Abnormality of the renal cortex (HP:0011035)1.74522830
98Febrile seizures (HP:0002373)1.73925551
99Renal dysplasia (HP:0000110)1.72048432
100Abnormal biliary tract physiology (HP:0012439)1.71328575
101Bile duct proliferation (HP:0001408)1.71328575
102Dyschromatopsia (HP:0007641)1.71219382
103Myokymia (HP:0002411)1.71085441
104Generalized aminoaciduria (HP:0002909)1.70177285
105Aplasia/Hypoplasia of the uvula (HP:0010293)1.70132769
106Male pseudohermaphroditism (HP:0000037)1.69996056
107Preaxial hand polydactyly (HP:0001177)1.69867306
108Patellar aplasia (HP:0006443)1.68972242
109Absent septum pellucidum (HP:0001331)1.67964182
110Abnormality of renal excretion (HP:0011036)1.67370657
111Postaxial hand polydactyly (HP:0001162)1.67073441
112Heterotopia (HP:0002282)1.65833978
113Fibular hypoplasia (HP:0003038)1.65409656
114Absent frontal sinuses (HP:0002688)1.64594286
115Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62805964
116Median cleft lip (HP:0000161)1.61992087
117Nephrogenic diabetes insipidus (HP:0009806)1.58986506
118Abnormality of ocular smooth pursuit (HP:0000617)1.58214417
119Aplasia/Hypoplasia of the lens (HP:0008063)1.58150587
120Genital tract atresia (HP:0001827)1.57931709
121Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.57624912
122Oculomotor apraxia (HP:0000657)1.57514257
123Deformed sella turcica (HP:0002681)1.54814739
124Spastic tetraparesis (HP:0001285)1.53723538
125Abnormality of the lower motor neuron (HP:0002366)1.52955041
126Optic nerve hypoplasia (HP:0000609)1.52368411
127Aplasia/Hypoplasia of the tongue (HP:0010295)1.51517507
128Cystic liver disease (HP:0006706)1.51341439
129Impaired smooth pursuit (HP:0007772)1.48334960
130Vaginal atresia (HP:0000148)1.46998328
131Abnormality of permanent molar morphology (HP:0011071)1.45625642
132Abnormality of the dental root (HP:0006486)1.45625642
133Taurodontia (HP:0000679)1.45625642
134Abnormal urine output (HP:0012590)1.41203395
135Choroideremia (HP:0001139)1.36884679
136Abnormality of molar (HP:0011077)1.36743817
137Abnormality of molar morphology (HP:0011070)1.36743817
138Poor coordination (HP:0002370)1.36409411
139Abnormality of the dental pulp (HP:0006479)1.34712148
140Abnormality of dentin (HP:0010299)1.31690626
141Chronic hepatic failure (HP:0100626)1.30972936
142Nephropathy (HP:0000112)1.29665133
143Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.29608659
144Cerebellar dysplasia (HP:0007033)1.29036887
145Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.25751182
146Absent epiphyses (HP:0010577)1.25751182
147Polyuria (HP:0000103)1.25229906
148Hemorrhage of the eye (HP:0011885)1.24501824
149Pachygyria (HP:0001302)1.24429553
150Short thorax (HP:0010306)1.24164704
151Bell-shaped thorax (HP:0001591)1.24051317
152Amyotrophic lateral sclerosis (HP:0007354)1.21203048
153True hermaphroditism (HP:0010459)1.20705379
154Hyporeflexia of lower limbs (HP:0002600)1.19426429

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.18812965
2PDK48.18812965
3TESK15.63590169
4PDK25.29579744
5PRKD34.87338975
6FRK4.04798456
7ICK3.86762553
8BMPR1B3.27525212
9ADRBK23.15228856
10MAP4K23.10498262
11PTK2B2.79218096
12INSRR2.67631170
13WNK42.66178222
14ZAK2.56936910
15STK392.43129088
16TAOK32.41324872
17TLK12.29057009
18WNK32.20402597
19NUAK12.16600771
20GRK12.04849802
21STK381.93537767
22MAPK131.87178813
23PNCK1.84303665
24TNIK1.80330778
25TRIM281.71139132
26MAP3K91.46763902
27NEK21.42772588
28ACVR1B1.41162096
29DYRK1B1.38471066
30CASK1.38404603
31PLK21.27773348
32VRK11.22881351
33PDK11.22567339
34TGFBR11.22415287
35DYRK21.20080638
36DAPK21.15670921
37TIE11.12169747
38TYRO31.00711778
39TXK0.97723064
40LMTK20.93477692
41PRKCI0.91985860
42NTRK30.89945248
43CSNK1G10.89704998
44WNK10.89319032
45ADRBK10.85531173
46DYRK30.84335143
47STK38L0.83436604
48NME10.78497090
49BRSK20.78068800
50PDPK10.77347500
51MAP2K70.75605579
52CAMKK20.75437130
53PRKCE0.74976198
54CAMK1D0.74913417
55MST40.74692774
56BCKDK0.74396150
57MAPK150.73990216
58CCNB10.73877126
59CHEK20.73831877
60TTK0.73660054
61CSNK1G30.71599132
62CAMK10.71360665
63VRK20.69389318
64PAK30.68287867
65WEE10.68206351
66CSNK1G20.67649064
67PLK30.67355864
68STK30.66603340
69EEF2K0.65260716
70PHKG10.63664248
71PHKG20.63664248
72STK160.62008452
73MAPKAPK30.61199343
74PASK0.59239299
75MKNK20.55499356
76IRAK10.55301623
77TNK20.55258885
78PRKACA0.55150183
79RIPK40.53894703
80PLK40.50250801
81PINK10.48634016
82CSNK1A1L0.47987807
83MAP2K60.46822936
84EPHA40.46287006
85EIF2AK30.45571411
86CHEK10.44335202
87CAMK1G0.44217528
88MUSK0.42231823
89KIT0.42012816
90PIK3CA0.41520935
91FGFR20.40744235
92MAP3K40.40367417
93CDK80.39627893
94RPS6KA50.38930613
95PRKCG0.37826439
96MAPKAPK50.37799555
97CHUK0.37055854
98CAMK40.37034288
99BRSK10.36777030
100RIPK10.36395791
101CDK70.35535211
102TESK20.35258436
103NTRK20.35146617
104PAK10.34626464
105IRAK20.34163000
106CSNK1A10.33564645
107BUB10.33520216
108MARK20.33438943
109TEC0.33376776
110PRKAA20.33159074
111ATM0.32463095
112NEK60.32026513
113ATR0.31126708
114ZAP700.30670785
115CDK120.30407604
116MARK30.24907133
117CAMKK10.24642870
118PAK20.20787040
119PDGFRB0.20152226
120PRKAA10.20002895
121CDC70.19815254
122MTOR0.18737688
123PLK10.17806175
124RPS6KB10.17332490
125PRKCZ0.14984356
126STK100.14377170
127PRKCQ0.14151708
128CDK150.12009515
129PKN10.11207323
130BRAF0.10458461
131STK110.10209053
132RPS6KA10.10193500
133GSK3B0.09255410
134CSNK2A20.08986997
135OXSR10.08968534
136CDK180.08919943
137PRKG20.08804222
138AURKA0.08765614
139CAMK2A0.08445140
140CSNK2A10.08392384
141CDK11A0.08138457
142LATS10.06681920
143CSNK1D0.06662355
144MAP2K40.06506360
145EGFR0.05959620
146CDK10.05662418
147PRKACG0.05549911
148MAPK80.05472397
149MARK10.05338827
150PRKG10.05309413
151MST1R0.04381820
152CDK20.04090379
153MINK10.03822366
154PRKDC0.03785359
155CDK140.03304963
156PRKCD0.03056156
157PRKCA0.03002715
158MAP3K100.02695500
159YES10.01166926
160PRKCB0.01048953
161MAP3K10.00952453
162PRKCH0.00843915

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.07664461
2Fatty acid biosynthesis_Homo sapiens_hsa000613.99597669
3Vitamin B6 metabolism_Homo sapiens_hsa007503.54976656
4Pyruvate metabolism_Homo sapiens_hsa006203.36677182
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.12417986
6alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.00777793
7Linoleic acid metabolism_Homo sapiens_hsa005912.91280086
8Phototransduction_Homo sapiens_hsa047442.87259684
9Pentose phosphate pathway_Homo sapiens_hsa000302.81923864
10Propanoate metabolism_Homo sapiens_hsa006402.79694821
11Basal transcription factors_Homo sapiens_hsa030222.63606442
12Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.58480234
13Glucagon signaling pathway_Homo sapiens_hsa049222.45857223
14Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.30734404
15Nicotine addiction_Homo sapiens_hsa050332.23029125
16Butanoate metabolism_Homo sapiens_hsa006502.17831524
17Oxidative phosphorylation_Homo sapiens_hsa001902.17807701
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.11270062
19Caffeine metabolism_Homo sapiens_hsa002322.03302013
20Nitrogen metabolism_Homo sapiens_hsa009101.98734686
21Carbohydrate digestion and absorption_Homo sapiens_hsa049731.96491686
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.96399678
23Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.95833333
24Glycosaminoglycan degradation_Homo sapiens_hsa005311.95399120
25Glycerolipid metabolism_Homo sapiens_hsa005611.92668179
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.89748868
27Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.86237300
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.85467283
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84344887
30Oocyte meiosis_Homo sapiens_hsa041141.83604126
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.80441873
32Parkinsons disease_Homo sapiens_hsa050121.80051136
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.79446151
34Selenocompound metabolism_Homo sapiens_hsa004501.78776781
35RNA polymerase_Homo sapiens_hsa030201.78115560
36Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.74766345
37PPAR signaling pathway_Homo sapiens_hsa033201.74557966
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.66637778
39Renin-angiotensin system_Homo sapiens_hsa046141.65330993
40RNA degradation_Homo sapiens_hsa030181.65093071
41Fanconi anemia pathway_Homo sapiens_hsa034601.62921613
42Morphine addiction_Homo sapiens_hsa050321.57235011
43Mineral absorption_Homo sapiens_hsa049781.56466252
44Ovarian steroidogenesis_Homo sapiens_hsa049131.56128621
45Amphetamine addiction_Homo sapiens_hsa050311.55593079
46Tryptophan metabolism_Homo sapiens_hsa003801.46085294
47Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.46075199
48Carbon metabolism_Homo sapiens_hsa012001.43667542
49Ether lipid metabolism_Homo sapiens_hsa005651.42607472
50Dorso-ventral axis formation_Homo sapiens_hsa043201.39075442
51Huntingtons disease_Homo sapiens_hsa050161.34415189
52Fat digestion and absorption_Homo sapiens_hsa049751.33269146
53Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.28990246
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.28274688
55Fructose and mannose metabolism_Homo sapiens_hsa000511.24419890
56Protein export_Homo sapiens_hsa030601.23752923
57Cardiac muscle contraction_Homo sapiens_hsa042601.22509114
58GABAergic synapse_Homo sapiens_hsa047271.20640510
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16974740
60Renin secretion_Homo sapiens_hsa049241.14344696
61Biosynthesis of amino acids_Homo sapiens_hsa012301.12864675
62Fatty acid metabolism_Homo sapiens_hsa012121.10652540
63Fatty acid degradation_Homo sapiens_hsa000711.09585382
64Serotonergic synapse_Homo sapiens_hsa047261.06514737
65mRNA surveillance pathway_Homo sapiens_hsa030151.03961730
66Collecting duct acid secretion_Homo sapiens_hsa049661.02243558
67Peroxisome_Homo sapiens_hsa041461.00862841
68Alzheimers disease_Homo sapiens_hsa050100.99007216
69Intestinal immune network for IgA production_Homo sapiens_hsa046720.98708259
70ABC transporters_Homo sapiens_hsa020100.97072815
71Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.95656536
72Cysteine and methionine metabolism_Homo sapiens_hsa002700.95038697
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.92585923
74Retinol metabolism_Homo sapiens_hsa008300.90369455
75Insulin secretion_Homo sapiens_hsa049110.89440566
76Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.89351114
77Purine metabolism_Homo sapiens_hsa002300.88427037
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.87978112
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.86909232
80Antigen processing and presentation_Homo sapiens_hsa046120.85064736
81Glutathione metabolism_Homo sapiens_hsa004800.84345442
82Regulation of autophagy_Homo sapiens_hsa041400.83414887
83Long-term potentiation_Homo sapiens_hsa047200.83355252
84Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.80267248
85Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.80151975
86RNA transport_Homo sapiens_hsa030130.79397932
87Synaptic vesicle cycle_Homo sapiens_hsa047210.78963978
88Nucleotide excision repair_Homo sapiens_hsa034200.76870929
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.76300792
90Asthma_Homo sapiens_hsa053100.75634339
91Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.75153497
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.74166691
93Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73333324
94Arachidonic acid metabolism_Homo sapiens_hsa005900.72217130
95One carbon pool by folate_Homo sapiens_hsa006700.71655006
96Mismatch repair_Homo sapiens_hsa034300.70034289
97Estrogen signaling pathway_Homo sapiens_hsa049150.69380109
98Lysine degradation_Homo sapiens_hsa003100.68502425
99Taste transduction_Homo sapiens_hsa047420.68320327
100Histidine metabolism_Homo sapiens_hsa003400.67558507
101Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66585256
102Thyroid hormone synthesis_Homo sapiens_hsa049180.66218037
103Bile secretion_Homo sapiens_hsa049760.64496195
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64265799
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62722211
106Ribosome_Homo sapiens_hsa030100.62177584
107Calcium signaling pathway_Homo sapiens_hsa040200.60451696
108cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59211473
109Systemic lupus erythematosus_Homo sapiens_hsa053220.58957836
110Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57842235
111Legionellosis_Homo sapiens_hsa051340.57413074
112Pancreatic secretion_Homo sapiens_hsa049720.56155383
113Endocytosis_Homo sapiens_hsa041440.56147980
114Hedgehog signaling pathway_Homo sapiens_hsa043400.54047801
115Chemical carcinogenesis_Homo sapiens_hsa052040.53673821
116beta-Alanine metabolism_Homo sapiens_hsa004100.53661098
117Protein digestion and absorption_Homo sapiens_hsa049740.52139549
118Long-term depression_Homo sapiens_hsa047300.51855142
119Vitamin digestion and absorption_Homo sapiens_hsa049770.51757021
120Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51100280
121Salivary secretion_Homo sapiens_hsa049700.50079835
122Proteasome_Homo sapiens_hsa030500.49820697
123AMPK signaling pathway_Homo sapiens_hsa041520.47911822
124Type I diabetes mellitus_Homo sapiens_hsa049400.46794264
125Gastric acid secretion_Homo sapiens_hsa049710.46439850
126Primary immunodeficiency_Homo sapiens_hsa053400.44545106
127Cocaine addiction_Homo sapiens_hsa050300.44160731
128Steroid biosynthesis_Homo sapiens_hsa001000.43874302
129Pyrimidine metabolism_Homo sapiens_hsa002400.42884338
130Inositol phosphate metabolism_Homo sapiens_hsa005620.42763549
131Vascular smooth muscle contraction_Homo sapiens_hsa042700.42665516
132Base excision repair_Homo sapiens_hsa034100.40439356
133Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.40209891
134Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.39948696
135Arginine and proline metabolism_Homo sapiens_hsa003300.39401097
136SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39394277
137N-Glycan biosynthesis_Homo sapiens_hsa005100.37811812
138Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37590316
139Metabolic pathways_Homo sapiens_hsa011000.36934553
140Allograft rejection_Homo sapiens_hsa053300.36152937
141Cholinergic synapse_Homo sapiens_hsa047250.35958715
142Circadian entrainment_Homo sapiens_hsa047130.35400389
143cAMP signaling pathway_Homo sapiens_hsa040240.34985776
144Sulfur metabolism_Homo sapiens_hsa009200.34750264
145Graft-versus-host disease_Homo sapiens_hsa053320.34416328
146Central carbon metabolism in cancer_Homo sapiens_hsa052300.32584017
147Olfactory transduction_Homo sapiens_hsa047400.30211859
148Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29970183
149Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.29767704
150Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.29751510
151Alcoholism_Homo sapiens_hsa050340.29573372
152Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.28423514
153Homologous recombination_Homo sapiens_hsa034400.26318354
154Salmonella infection_Homo sapiens_hsa051320.25556735
155Aldosterone synthesis and secretion_Homo sapiens_hsa049250.21241474
156Glutamatergic synapse_Homo sapiens_hsa047240.20940500
157Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17334622
158VEGF signaling pathway_Homo sapiens_hsa043700.13194832
159Insulin resistance_Homo sapiens_hsa049310.12660724
160Dopaminergic synapse_Homo sapiens_hsa047280.10994044

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