CCDC33

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.91871741
2sensory perception of smell (GO:0007608)9.90615982
3sperm motility (GO:0030317)9.80610970
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.48304058
5regulation of cilium movement (GO:0003352)9.41057755
6axoneme assembly (GO:0035082)8.87514449
7fusion of sperm to egg plasma membrane (GO:0007342)8.81500286
8acrosome reaction (GO:0007340)8.00918986
9cell wall macromolecule catabolic process (GO:0016998)7.98828026
10cell wall macromolecule metabolic process (GO:0044036)7.98828026
11sperm-egg recognition (GO:0035036)7.58617231
12ventricular system development (GO:0021591)7.53085137
13acrosome assembly (GO:0001675)7.46970601
14primary alcohol catabolic process (GO:0034310)7.29834443
15GTP biosynthetic process (GO:0006183)7.24895586
16microtubule severing (GO:0051013)7.17899056
17multicellular organism reproduction (GO:0032504)7.16497730
18binding of sperm to zona pellucida (GO:0007339)7.09312062
19vitamin transmembrane transport (GO:0035461)7.03005175
20protein localization to cilium (GO:0061512)7.02599779
21spermatid development (GO:0007286)6.88290412
22cell-cell recognition (GO:0009988)6.82929000
23plasma membrane fusion (GO:0045026)6.66514283
24UTP biosynthetic process (GO:0006228)6.44262467
25nucleoside diphosphate phosphorylation (GO:0006165)6.33305875
26negative regulation of inclusion body assembly (GO:0090084)6.18557018
27reproduction (GO:0000003)6.16926613
28ethanol metabolic process (GO:0006067)6.11879610
29single fertilization (GO:0007338)6.10951118
30UTP metabolic process (GO:0046051)5.86066608
31diterpenoid biosynthetic process (GO:0016102)5.81713759
32sensory perception of chemical stimulus (GO:0007606)5.72519124
33intraciliary transport (GO:0042073)5.66812462
34left/right axis specification (GO:0070986)5.60672797
35regulation of microtubule-based movement (GO:0060632)5.55262131
36lung epithelium development (GO:0060428)5.43656145
37guanosine-containing compound biosynthetic process (GO:1901070)5.40165744
38protein polyglutamylation (GO:0018095)5.36703455
39cilium morphogenesis (GO:0060271)5.35502671
40fertilization (GO:0009566)5.21765145
41one-carbon compound transport (GO:0019755)5.12682701
42piRNA metabolic process (GO:0034587)5.04934539
43microtubule bundle formation (GO:0001578)5.02375067
44response to xenobiotic stimulus (GO:0009410)5.00755240
45glomerular epithelial cell development (GO:0072310)4.96631051
46regulation of inclusion body assembly (GO:0090083)4.96034062
47establishment of apical/basal cell polarity (GO:0035089)4.91585002
48pyrimidine-containing compound transmembrane transport (GO:0072531)4.86193823
49spermatogenesis (GO:0007283)4.85947229
50sperm capacitation (GO:0048240)4.85593399
51male meiosis (GO:0007140)4.84208255
52male gamete generation (GO:0048232)4.83493834
53cilium organization (GO:0044782)4.80836937
54CTP biosynthetic process (GO:0006241)4.78238735
55CTP metabolic process (GO:0046036)4.78238735
56negative regulation of T cell differentiation in thymus (GO:0033085)4.70557417
57protein insertion into membrane (GO:0051205)4.66900930
58cilium assembly (GO:0042384)4.65186862
59tolerance induction (GO:0002507)4.62228542
60ethanol oxidation (GO:0006069)4.61360743
61regulation of interleukin-5 production (GO:0032674)4.55333421
62establishment or maintenance of monopolar cell polarity (GO:0061339)4.53083115
63establishment of monopolar cell polarity (GO:0061162)4.53083115
64synaptonemal complex organization (GO:0070193)4.47721066
65gamete generation (GO:0007276)4.45344003
66microtubule polymerization or depolymerization (GO:0031109)4.41086182
67pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.35551572
68terpenoid biosynthetic process (GO:0016114)4.32834962
69retinoic acid metabolic process (GO:0042573)4.31141775
70spermatid nucleus differentiation (GO:0007289)4.25763335
71left/right pattern formation (GO:0060972)4.22174954
72regulation of interleukin-13 production (GO:0032656)4.20964597
73negative regulation of immunoglobulin mediated immune response (GO:0002890)4.19493717
74negative regulation of B cell mediated immunity (GO:0002713)4.19493717
75cellular component assembly involved in morphogenesis (GO:0010927)4.14054840
76calcium ion-dependent exocytosis (GO:0017156)4.08199927
77pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.04949109
78microtubule-based movement (GO:0007018)4.03866412
79negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.01125571
80organic cation transport (GO:0015695)3.94495881
81synaptonemal complex assembly (GO:0007130)3.91993383
82cytoplasmic microtubule organization (GO:0031122)3.74787587
83positive regulation of tolerance induction (GO:0002645)3.71104965
84germ cell development (GO:0007281)3.67853886
85regulation of germinal center formation (GO:0002634)3.66451016
86establishment of tissue polarity (GO:0007164)3.65028320
87establishment of planar polarity (GO:0001736)3.65028320
88cell recognition (GO:0008037)3.62121953
89multicellular organismal reproductive process (GO:0048609)3.58393833
90cellular process involved in reproduction in multicellular organism (GO:0022412)3.57883811
91pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.50608153
92lateral ventricle development (GO:0021670)3.48083398
93exogenous drug catabolic process (GO:0042738)3.35755271
94nucleotide phosphorylation (GO:0046939)3.32348548
95regulation of protein kinase A signaling (GO:0010738)3.29229342
96microtubule depolymerization (GO:0007019)3.27226042
97primary alcohol metabolic process (GO:0034308)3.24517820
98positive regulation of smoothened signaling pathway (GO:0045880)3.24313964
99male meiosis I (GO:0007141)3.23004924
100pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.16967369
101retinol metabolic process (GO:0042572)3.16531055
102cell projection assembly (GO:0030031)3.14946939
103glutathione derivative biosynthetic process (GO:1901687)3.10898013
104glutathione derivative metabolic process (GO:1901685)3.10898013
105DNA methylation involved in gamete generation (GO:0043046)3.06410216
106brain morphogenesis (GO:0048854)3.02921101
107nucleoside diphosphate metabolic process (GO:0009132)3.01694149
108O-glycan processing (GO:0016266)2.99475893
109aldehyde catabolic process (GO:0046185)2.98238177
110determination of left/right symmetry (GO:0007368)2.97606323
111lateral sprouting from an epithelium (GO:0060601)2.96906351
112glycerol ether metabolic process (GO:0006662)2.96148699
113microtubule-based process (GO:0007017)2.93902788
114regulation of female gonad development (GO:2000194)2.92702880
115C21-steroid hormone biosynthetic process (GO:0006700)2.88581724
116regulation of microtubule depolymerization (GO:0031114)2.88557110
117determination of bilateral symmetry (GO:0009855)2.86705237
118specification of symmetry (GO:0009799)2.80483794
119excretion (GO:0007588)2.79517971
120multicellular organismal water homeostasis (GO:0050891)2.77394192
121peptidyl-threonine dephosphorylation (GO:0035970)2.76078313
122ether metabolic process (GO:0018904)2.73314474
123organelle assembly (GO:0070925)2.73011180
124protein refolding (GO:0042026)2.72471871
125multicellular organismal development (GO:0007275)2.72018332
126smoothened signaling pathway (GO:0007224)2.71907245
127carnitine metabolic process (GO:0009437)2.71527784
128peptidyl-glutamic acid modification (GO:0018200)2.68811597
129sexual reproduction (GO:0019953)2.68427700
130regulation of tolerance induction (GO:0002643)2.65602839
131centriole assembly (GO:0098534)2.63241911
132phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.62999323
133drug catabolic process (GO:0042737)2.61927241
134hydrogen peroxide catabolic process (GO:0042744)2.61389600
135natural killer cell mediated cytotoxicity (GO:0042267)2.61043626
136natural killer cell mediated immunity (GO:0002228)2.61043626
137phosphatidylethanolamine biosynthetic process (GO:0006646)2.59371646
138single strand break repair (GO:0000012)2.59346687
139hydrogen peroxide biosynthetic process (GO:0050665)2.58857249
140regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.56897274
141retinal rod cell development (GO:0046548)2.56476626
142meiosis I (GO:0007127)2.56174831
143centriole replication (GO:0007099)2.55969879
144meiotic nuclear division (GO:0007126)2.55881901
145nonmotile primary cilium assembly (GO:0035058)2.55706780
146pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.54513664
147apical protein localization (GO:0045176)2.54053649
148phosphatidylcholine biosynthetic process (GO:0006656)2.52081985
149calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.51955512
150negative regulation of humoral immune response (GO:0002921)2.50703400
151regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.49390085
152establishment or maintenance of bipolar cell polarity (GO:0061245)2.48835014
153establishment or maintenance of apical/basal cell polarity (GO:0035088)2.48835014
154heart looping (GO:0001947)2.47512996
155meiotic cell cycle (GO:0051321)2.47110147
156ear development (GO:0043583)2.47018082
157oligosaccharide biosynthetic process (GO:0009312)2.45197629
158pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.44215853
159cAMP biosynthetic process (GO:0006171)2.43773808
160detection of calcium ion (GO:0005513)2.42328993
161chromosome organization involved in meiosis (GO:0070192)2.38756873
162axonemal dynein complex assembly (GO:0070286)13.7944816
163cilium movement (GO:0003341)12.7771867
164cilium or flagellum-dependent cell motility (GO:0001539)11.7883633
165epithelial cilium movement (GO:0003351)11.7361249

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.28879263
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.90731747
3EZH2_22144423_ChIP-Seq_EOC_Human4.78029656
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.33094484
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.16782168
6GATA1_26923725_Chip-Seq_HPCs_Mouse3.05593508
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.86605986
8* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.86017460
9TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.84568763
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.50060530
11STAT6_21828071_ChIP-Seq_BEAS2B_Human2.35428435
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.03485717
13TRIM28_21343339_ChIP-Seq_HEK293_Human1.98491744
14SMC4_20622854_ChIP-Seq_HELA_Human1.97766880
15ESR1_20079471_ChIP-ChIP_T-47D_Human1.89006893
16STAT1_20625510_ChIP-Seq_HELA_Human1.78958897
17RUNX1_27514584_Chip-Seq_MCF-7_Human1.74379530
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.70004079
19CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.69183656
20MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.66957160
21DROSHA_22980978_ChIP-Seq_HELA_Human1.64904765
22TP63_22573176_ChIP-Seq_HFKS_Human1.64901218
23PIAS1_25552417_ChIP-Seq_VCAP_Human1.62830096
24TDRD3_21172665_ChIP-Seq_MCF-7_Human1.61701268
25POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.61191273
26TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61191273
27FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.61159640
28CTCF_27219007_Chip-Seq_Bcells_Human1.59927425
29TAL1_26923725_Chip-Seq_HPCs_Mouse1.57173961
30VDR_22108803_ChIP-Seq_LS180_Human1.56844024
31ELF1_20517297_ChIP-Seq_JURKAT_Human1.56595638
32RNF2_27304074_Chip-Seq_NSC_Mouse1.56158881
33ETV1_20927104_ChIP-Seq_GIST48_Human1.56149238
34EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.55641957
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.54949952
36WDR5_24793694_ChIP-Seq_LNCAP_Human1.54688810
37TP63_23658742_ChIP-Seq_EP156T_Human1.54580117
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.54578725
39ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.54043682
40* REST_21632747_ChIP-Seq_MESCs_Mouse1.52493407
41KLF5_25053715_ChIP-Seq_YYC3_Human1.50957831
42PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.46348054
43* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.45416490
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.44749784
45SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.44697957
46FOXM1_26456572_ChIP-Seq_MCF-7_Human1.44179295
47PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43989903
48TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43665292
49YY1_22570637_ChIP-Seq_MALME-3M_Human1.43649079
50P63_26484246_Chip-Seq_KERATINOCYTES_Human1.43416605
51HNFA_21074721_ChIP-Seq_CACO-2_Human1.43081634
52SOX2_22085726_ChIP-Seq_NPCs_Mouse1.42634664
53CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.41662032
54PHF8_20622853_ChIP-Seq_HELA_Human1.41565463
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.41343451
56* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41263798
57ELK4_26923725_Chip-Seq_MESODERM_Mouse1.40332152
58TP53_18474530_ChIP-ChIP_U2OS_Human1.40294911
59* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.39233308
60SOX2_27498859_Chip-Seq_STOMACH_Mouse1.38613114
61CTCF_20526341_ChIP-Seq_ESCs_Human1.38151977
62RBPJ_21746931_ChIP-Seq_IB4_Human1.36440219
63ESR2_21235772_ChIP-Seq_MCF-7_Human1.36395686
64PHF8_20622854_ChIP-Seq_HELA_Human1.34864377
65KAP1_22055183_ChIP-Seq_ESCs_Mouse1.34538162
66AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.34191179
67* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.32798077
68SUZ12_27294783_Chip-Seq_ESCs_Mouse1.32513562
69SMAD4_21799915_ChIP-Seq_A2780_Human1.31154637
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.30230382
71P68_20966046_ChIP-Seq_HELA_Human1.29830194
72SMAD4_21741376_ChIP-Seq_EPCs_Human1.27766479
73CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.27208728
74ESR1_21235772_ChIP-Seq_MCF-7_Human1.27164843
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27114854
76EZH2_27294783_Chip-Seq_ESCs_Mouse1.26626599
77TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.26537047
78CBX2_22325352_ChIP-Seq_293T-Rex_Human1.25385100
79LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25232898
80GF1_26923725_Chip-Seq_HPCs_Mouse1.24283200
81SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.23651125
82SMRT_27268052_Chip-Seq_Bcells_Human1.23083184
83CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21528487
84EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.21277748
85GATA6_21074721_ChIP-Seq_CACO-2_Human1.20677366
86ARNT_22903824_ChIP-Seq_MCF-7_Human1.20256923
87ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19775349
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.19605835
89P53_21459846_ChIP-Seq_SAOS-2_Human1.19466763
90NFYA_21822215_ChIP-Seq_K562_Human1.18911489
91STAT1_17558387_ChIP-Seq_HELA_Human1.15683525
92FOXA1_25552417_ChIP-Seq_VCAP_Human1.15495903
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.15206951
94SUZ12_27294783_Chip-Seq_NPCs_Mouse1.15068336
95NFYB_21822215_ChIP-Seq_K562_Human1.14888763
96GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.14141258
97CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14137299
98NANOG_18555785_Chip-Seq_ESCs_Mouse1.13669370
99SMAD3_21741376_ChIP-Seq_ESCs_Human1.12288384
100P53_22387025_ChIP-Seq_ESCs_Mouse1.11119686
101NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10649794
102CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10579495
103SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.10317110
104CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10117724
105LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09896949
106CBP_20019798_ChIP-Seq_JUKART_Human1.09543137
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.09543137
108NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.08559072
109CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07736812
110RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.07261086
111P300_27268052_Chip-Seq_Bcells_Human1.07061413
112MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.06711967
113GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.06593952
114GBX2_23144817_ChIP-Seq_PC3_Human1.05838651
115TAF15_26573619_Chip-Seq_HEK293_Human1.05545016
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05184006
117E2F1_20622854_ChIP-Seq_HELA_Human1.05029992
118CDX2_20551321_ChIP-Seq_CACO-2_Human1.04018306
119SOX2_20726797_ChIP-Seq_SW620_Human1.03932353
120ER_23166858_ChIP-Seq_MCF-7_Human1.03300079
121CMYC_18555785_Chip-Seq_ESCs_Mouse1.03054515
122FLI1_21867929_ChIP-Seq_TH2_Mouse1.02770802
123SOX2_21211035_ChIP-Seq_LN229_Human1.02349036
124KDM2B_26808549_Chip-Seq_REH_Human1.01672919
125OCT4_18555785_Chip-Seq_ESCs_Mouse1.01589468
126SMAD3_21741376_ChIP-Seq_EPCs_Human1.00931164
127GATA3_21867929_ChIP-Seq_TH1_Mouse1.00879136
128P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.00147057
129MYC_19829295_ChIP-Seq_ESCs_Human0.99831428
130KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.99765226
131LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.99651759
132AR_21572438_ChIP-Seq_LNCaP_Human0.99587577
133CREB1_26743006_Chip-Seq_LNCaP_Human0.99486380
134* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.99411547
135TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99409480
136ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.99373950
137FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.98737012
138MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98461839
139* CEBPB_22108803_ChIP-Seq_LS180_Human0.98182934
140AHR_22903824_ChIP-Seq_MCF-7_Human0.97618847
141VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.97528211
142GATA4_25053715_ChIP-Seq_YYC3_Human0.97296841
143ERA_21632823_ChIP-Seq_H3396_Human0.96682585
144GATA3_24758297_ChIP-Seq_MCF-7_Human0.96495415
145SPI1_26923725_Chip-Seq_HPCs_Mouse0.96298497
146* GATA3_21867929_ChIP-Seq_CD8_Mouse0.96094135
147* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95890077
148P300_19829295_ChIP-Seq_ESCs_Human0.95693416
149TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95610160
150EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95230254
151FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95091594
152SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.95067274
153TBL1_22424771_ChIP-Seq_293T_Human0.94485007
154CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.94025009
155GF1B_26923725_Chip-Seq_HPCs_Mouse0.93904409
156SMAD3_21741376_ChIP-Seq_HESCs_Human0.93819558
157FUS_26573619_Chip-Seq_HEK293_Human0.92419280
158SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92338159
159NANOG_20526341_ChIP-Seq_ESCs_Human0.92325856
160SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.92088585
161BCOR_27268052_Chip-Seq_Bcells_Human0.91857695
162TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.91614660
163* OCT4_20526341_ChIP-Seq_ESCs_Human0.91603711
164PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.91378891
165GATA1_19941826_ChIP-Seq_K562_Human0.90850189
166RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.90684660
167RUNX1_26923725_Chip-Seq_HPCs_Mouse0.90650843
168P300_18555785_Chip-Seq_ESCs_Mouse0.90580981
169FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.90026489
170ZNF274_21170338_ChIP-Seq_K562_Hela0.89720437
171LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89450838
172SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89175899
173AUTS2_25519132_ChIP-Seq_293T-REX_Human0.89148147
174NCOR_22424771_ChIP-Seq_293T_Human0.89050469
175RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88985707
176RAD21_21589869_ChIP-Seq_MESCs_Mouse0.88799289
177E2F1_18555785_Chip-Seq_ESCs_Mouse0.88475003
178RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88287269
179AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.87946388

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction9.72810721
2MP0008875_abnormal_xenobiotic_pharmacok6.72382308
3MP0002132_abnormal_respiratory_system5.37716310
4MP0003698_abnormal_male_reproductive4.25700003
5MP0002653_abnormal_ependyma_morphology3.91419141
6MP0001929_abnormal_gametogenesis3.54306036
7MP0004043_abnormal_pH_regulation3.33055201
8MP0002277_abnormal_respiratory_mucosa3.32324794
9MP0009780_abnormal_chondrocyte_physiolo3.31742390
10MP0003136_yellow_coat_color3.02290651
11MP0000566_synostosis2.90645194
12MP0002160_abnormal_reproductive_system2.68882357
13MP0005623_abnormal_meninges_morphology2.47421798
14MP0002210_abnormal_sex_determination2.36972914
15MP0002161_abnormal_fertility/fecundity2.33793002
16MP0004019_abnormal_vitamin_homeostasis2.23585322
17MP0000678_abnormal_parathyroid_gland2.10417651
18MP0005083_abnormal_biliary_tract2.02710252
19MP0005410_abnormal_fertilization11.2805572
20MP0000383_abnormal_hair_follicle1.96069855
21MP0008877_abnormal_DNA_methylation1.92686420
22MP0001145_abnormal_male_reproductive1.90601188
23MP0008004_abnormal_stomach_pH1.88429057
24MP0002254_reproductive_system_inflammat1.87308750
25MP0002928_abnormal_bile_duct1.76723405
26MP0010678_abnormal_skin_adnexa1.76401766
27MP0002168_other_aberrant_phenotype1.71898572
28MP0000653_abnormal_sex_gland1.71704795
29MP0005647_abnormal_sex_gland1.65100342
30MP0004133_heterotaxia1.63210462
31MP0002249_abnormal_larynx_morphology1.60781897
32MP0005670_abnormal_white_adipose1.58052866
33MP0001346_abnormal_lacrimal_gland1.55923334
34MP0009379_abnormal_foot_pigmentation1.53222536
35MP0005646_abnormal_pituitary_gland1.50425867
36MP0003656_abnormal_erythrocyte_physiolo1.49079214
37MP0005248_abnormal_Harderian_gland1.41475386
38MP0010234_abnormal_vibrissa_follicle1.36291473
39MP0010030_abnormal_orbit_morphology1.33714334
40MP0005394_taste/olfaction_phenotype1.30979940
41MP0005499_abnormal_olfactory_system1.30979940
42MP0008789_abnormal_olfactory_epithelium1.29482724
43MP0005395_other_phenotype1.28959592
44MP0009046_muscle_twitch1.28519846
45MP0005377_hearing/vestibular/ear_phenot1.24991558
46MP0003878_abnormal_ear_physiology1.24991558
47MP0002282_abnormal_trachea_morphology1.24678634
48MP0001485_abnormal_pinna_reflex1.23302745
49MP0002184_abnormal_innervation1.20795714
50MP0005551_abnormal_eye_electrophysiolog1.19219660
51MP0005389_reproductive_system_phenotype1.16594946
52MP0002557_abnormal_social/conspecific_i1.09287402
53MP0001486_abnormal_startle_reflex1.08393979
54MP0005636_abnormal_mineral_homeostasis1.08144978
55MP0002822_catalepsy1.05206406
56MP0002752_abnormal_somatic_nervous1.02225324
57MP0000681_abnormal_thyroid_gland0.96937362
58MP0001502_abnormal_circadian_rhythm0.95723131
59MP0004264_abnormal_extraembryonic_tissu0.95646306
60MP0008995_early_reproductive_senescence0.95275842
61MP0002272_abnormal_nervous_system0.94934939
62MP0002102_abnormal_ear_morphology0.93719135
63MP0002909_abnormal_adrenal_gland0.92874330
64MP0002735_abnormal_chemical_nociception0.91716036
65MP0001501_abnormal_sleep_pattern0.91613156
66MP0005645_abnormal_hypothalamus_physiol0.90457149
67MP0003806_abnormal_nucleotide_metabolis0.89203684
68MP0001765_abnormal_ion_homeostasis0.88740923
69MP0003635_abnormal_synaptic_transmissio0.86057656
70MP0004811_abnormal_neuron_physiology0.85481969
71MP0005165_increased_susceptibility_to0.85341375
72MP0002098_abnormal_vibrissa_morphology0.80134689
73MP0002882_abnormal_neuron_morphology0.79578184
74MP0004381_abnormal_hair_follicle0.76032460
75MP0005408_hypopigmentation0.75582364
76MP0009643_abnormal_urine_homeostasis0.74433393
77MP0004742_abnormal_vestibular_system0.74347840
78MP0002152_abnormal_brain_morphology0.73129664
79MP0001188_hyperpigmentation0.73079760
80MP0001873_stomach_inflammation0.72892495
81MP0003634_abnormal_glial_cell0.72256930
82MP0002734_abnormal_mechanical_nocicepti0.72025719
83MP0002572_abnormal_emotion/affect_behav0.71904062
84MP0010155_abnormal_intestine_physiology0.71296096
85MP0000778_abnormal_nervous_system0.70713630
86MP0004145_abnormal_muscle_electrophysio0.70413275
87MP0004858_abnormal_nervous_system0.69932255
88MP0001849_ear_inflammation0.69024954
89MP0005503_abnormal_tendon_morphology0.68049598
90MP0001293_anophthalmia0.67723731
91MP0002136_abnormal_kidney_physiology0.66822364
92MP0001851_eye_inflammation0.66119419
93MP0002229_neurodegeneration0.65866614
94MP0003718_maternal_effect0.64797457
95MP0002063_abnormal_learning/memory/cond0.64377970
96MP0001299_abnormal_eye_distance/0.63762586
97MP0001324_abnormal_eye_pigmentation0.63493631
98MP0005423_abnormal_somatic_nervous0.61120999
99MP0003942_abnormal_urinary_system0.60738717
100MP0005365_abnormal_bile_salt0.59817025
101MP0005195_abnormal_posterior_eye0.59324814
102MP0002116_abnormal_craniofacial_bone0.58922000
103MP0000955_abnormal_spinal_cord0.58649772
104MP0005220_abnormal_exocrine_pancreas0.58526702
105MP0003941_abnormal_skin_development0.58090578
106MP0000465_gastrointestinal_hemorrhage0.57128581
107MP0002064_seizures0.56379100
108MP0001970_abnormal_pain_threshold0.55965400
109MP0006082_CNS_inflammation0.54804990
110MP0009703_decreased_birth_body0.54376169
111MP0005310_abnormal_salivary_gland0.54120746
112MP0003938_abnormal_ear_development0.53958773
113MP0001270_distended_abdomen0.53623240
114MP0000467_abnormal_esophagus_morphology0.53592837
115MP0003861_abnormal_nervous_system0.52954735
116MP0002084_abnormal_developmental_patter0.52922934
117MP0005164_abnormal_response_to0.52574409
118MP0009745_abnormal_behavioral_response0.52194654
119MP0009115_abnormal_fat_cell0.50353789
120MP0004883_abnormal_blood_vessel0.49637307
121MP0003329_amyloid_beta_deposits0.49589309
122MP0009765_abnormal_xenobiotic_induced0.49051496
123MP0002638_abnormal_pupillary_reflex0.47175959
124MP0001440_abnormal_grooming_behavior0.47061434
125MP0003880_abnormal_central_pattern0.46791867
126MP0003633_abnormal_nervous_system0.46589801
127MP0002876_abnormal_thyroid_physiology0.46358861
128MP0002092_abnormal_eye_morphology0.45402126
129MP0005391_vision/eye_phenotype0.44664460
130MP0006036_abnormal_mitochondrial_physio0.44318296
131MP0002405_respiratory_system_inflammati0.44253599
132MP0002896_abnormal_bone_mineralization0.43897684
133MP0002067_abnormal_sensory_capabilities0.43059472
134MP0002295_abnormal_pulmonary_circulatio0.43021121
135MP0001664_abnormal_digestion0.42896463
136MP0004270_analgesia0.42778978
137MP0001963_abnormal_hearing_physiology0.42389881
138MP0000026_abnormal_inner_ear0.42114343
139MP0000049_abnormal_middle_ear0.40499247
140MP0003011_delayed_dark_adaptation0.39976698
141MP0003937_abnormal_limbs/digits/tail_de0.39323975
142MP0000631_abnormal_neuroendocrine_gland0.38744032
143MP0002233_abnormal_nose_morphology0.36688506
144MP0003879_abnormal_hair_cell0.35437118
145MP0003045_fibrosis0.35403595
146MP0004130_abnormal_muscle_cell0.34730139
147MP0003252_abnormal_bile_duct0.34154474
148MP0002109_abnormal_limb_morphology0.33896487
149MP0000428_abnormal_craniofacial_morphol0.33644327
150MP0005253_abnormal_eye_physiology0.33209672
151MP0001348_abnormal_lacrimal_gland0.33124598
152MP0005388_respiratory_system_phenotype0.32835207
153MP0002133_abnormal_respiratory_system0.32835207

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.55966574
2Abnormal respiratory motile cilium morphology (HP:0005938)9.30742555
3Abnormal respiratory epithelium morphology (HP:0012253)9.30742555
4Rhinitis (HP:0012384)9.07070895
5Chronic bronchitis (HP:0004469)7.66902118
6Nasal polyposis (HP:0100582)5.86646775
7Bronchiectasis (HP:0002110)5.23855990
8Abnormality of the nasal mucosa (HP:0000433)4.82476811
9Infertility (HP:0000789)4.45048704
10Bronchitis (HP:0012387)4.07262398
11Male infertility (HP:0003251)3.88785081
12Recurrent sinusitis (HP:0011108)3.61747359
13Nephronophthisis (HP:0000090)3.58053133
14Molar tooth sign on MRI (HP:0002419)3.28693538
15Abnormality of midbrain morphology (HP:0002418)3.28693538
16Retinal dysplasia (HP:0007973)3.14990315
17Recurrent otitis media (HP:0000403)3.09985116
18True hermaphroditism (HP:0010459)3.05994020
19Hyperactive renin-angiotensin system (HP:0000841)3.01219862
20Tubulointerstitial nephritis (HP:0001970)2.90529226
21Pancreatic fibrosis (HP:0100732)2.89956503
22Medial flaring of the eyebrow (HP:0010747)2.82805710
23Chronic otitis media (HP:0000389)2.81222664
24Abnormal biliary tract physiology (HP:0012439)2.72031047
25Bile duct proliferation (HP:0001408)2.72031047
26Abnormality of the renal medulla (HP:0100957)2.66990052
27Supernumerary spleens (HP:0009799)2.56233934
28Occipital encephalocele (HP:0002085)2.51785659
29Gait imbalance (HP:0002141)2.50828984
30Congenital primary aphakia (HP:0007707)2.46401184
31Insidious onset (HP:0003587)2.45705133
32Termporal pattern (HP:0011008)2.45705133
33Abnormality of dentin (HP:0010299)2.41609486
34Cystic liver disease (HP:0006706)2.38339795
35Chronic sinusitis (HP:0011109)2.32374472
36Pancreatic cysts (HP:0001737)2.29688609
37Postaxial foot polydactyly (HP:0001830)2.27524813
38Congenital hepatic fibrosis (HP:0002612)2.17095664
39Nephrogenic diabetes insipidus (HP:0009806)2.15833582
40Bifid tongue (HP:0010297)2.12914076
41Oculomotor apraxia (HP:0000657)2.10164173
42Chronic hepatic failure (HP:0100626)2.09633909
43Bony spicule pigmentary retinopathy (HP:0007737)2.05010774
44Abnormality of permanent molar morphology (HP:0011071)2.03773772
45Abnormality of the dental root (HP:0006486)2.03773772
46Taurodontia (HP:0000679)2.03773772
47Short nail (HP:0001799)2.03172981
48Median cleft lip (HP:0000161)2.03128693
49Postaxial hand polydactyly (HP:0001162)2.02120761
50Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.9675729
51Abnormal respiratory motile cilium physiology (HP:0012261)11.0777055
52Absent/shortened dynein arms (HP:0200106)10.1914264
53Dynein arm defect of respiratory motile cilia (HP:0012255)10.1914264
54Tubulointerstitial abnormality (HP:0001969)1.94187078
55Asplenia (HP:0001746)1.93333801
56Abnormality of molar (HP:0011077)1.92174635
57Abnormality of molar morphology (HP:0011070)1.92174635
58Disinhibition (HP:0000734)1.91316381
59Renal salt wasting (HP:0000127)1.87403410
60Genital tract atresia (HP:0001827)1.86086877
61Decreased circulating renin level (HP:0003351)1.85823125
62Vaginal atresia (HP:0000148)1.85243134
63Aplasia/Hypoplasia of the lens (HP:0008063)1.85221669
64Abnormality of the dental pulp (HP:0006479)1.85167409
65Aplasia/Hypoplasia of the tongue (HP:0010295)1.85074000
66Tubular atrophy (HP:0000092)1.84837819
67Aplasia/Hypoplasia of the spleen (HP:0010451)1.82437797
68Degeneration of the lateral corticospinal tracts (HP:0002314)1.82109684
69Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.82109684
70Hyperkalemia (HP:0002153)1.76028557
71Poor coordination (HP:0002370)1.74783567
72Male pseudohermaphroditism (HP:0000037)1.73335792
73Absent frontal sinuses (HP:0002688)1.67815033
74Recurrent bronchitis (HP:0002837)1.67502585
75Stage 5 chronic kidney disease (HP:0003774)1.63931538
76Hypotelorism (HP:0000601)1.57879202
77Genetic anticipation (HP:0003743)1.57600889
78Sclerocornea (HP:0000647)1.55796031
79Hyperaldosteronism (HP:0000859)1.53326786
80Abnormality of macular pigmentation (HP:0008002)1.53042259
81Facial cleft (HP:0002006)1.51097736
82Dyschromatopsia (HP:0007641)1.49871459
83Limb dystonia (HP:0002451)1.48964189
84Fibular hypoplasia (HP:0003038)1.45667042
85Constricted visual fields (HP:0001133)1.44638495
86Back pain (HP:0003418)1.42634877
87Abnormality of the corticospinal tract (HP:0002492)1.41476732
88Bell-shaped thorax (HP:0001591)1.40749303
89Hand muscle atrophy (HP:0009130)1.39298000
90Abnormal spermatogenesis (HP:0008669)1.38314886
91Broad distal phalanx of finger (HP:0009836)1.37564317
92Abnormality of renin-angiotensin system (HP:0000847)1.37026540
93Abnormality of chloride homeostasis (HP:0011422)1.35436161
94Anencephaly (HP:0002323)1.34979606
95Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.34172507
96Furrowed tongue (HP:0000221)1.33157470
97Retinitis pigmentosa (HP:0000510)1.31178002
98Absent rod-and cone-mediated responses on ERG (HP:0007688)1.29257723
99Specific learning disability (HP:0001328)1.29053688
100Preaxial hand polydactyly (HP:0001177)1.26873187
101Nephropathy (HP:0000112)1.25840464
102Cone-rod dystrophy (HP:0000548)1.24529228
103Fetal akinesia sequence (HP:0001989)1.24121409
104Hyponatremia (HP:0002902)1.23860707
105Short ribs (HP:0000773)1.23584958
106Hypochromic microcytic anemia (HP:0004840)1.23531114
107Atelectasis (HP:0100750)1.23490527
108Short thorax (HP:0010306)1.22475359
109Polydipsia (HP:0001959)1.22308739
110Abnormal drinking behavior (HP:0030082)1.22308739
111Tubulointerstitial fibrosis (HP:0005576)1.19695256
112Abolished electroretinogram (ERG) (HP:0000550)1.19279072
113Hypokalemic alkalosis (HP:0001949)1.19118367
114Narrow forehead (HP:0000341)1.18971900
115Dysphonia (HP:0001618)1.18754492
116Bifid scrotum (HP:0000048)1.17094242
117Apathy (HP:0000741)1.16510709
118Abnormality of the distal phalanges of the toes (HP:0010182)1.14791033
119Decreased central vision (HP:0007663)1.13972978
120Glucose intolerance (HP:0000833)1.13072024
121Abnormality of the frontal sinuses (HP:0002687)1.11723707
122Short femoral neck (HP:0100864)1.10074228
123Popliteal pterygium (HP:0009756)1.06242223
124Renal dysplasia (HP:0000110)1.04283121
125Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.04187374
126Abnormal rod and cone electroretinograms (HP:0008323)1.01389937
127Lip pit (HP:0100267)0.98558665
128Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)0.97339904

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK35.99653177
2PDK45.99653177
3MAPK154.95249468
4EPHA24.87246803
5TESK14.34744092
6ICK4.18914795
7PRKD33.99618116
8PNCK3.84220104
9PDK23.69376089
10EEF2K3.01890185
11NME12.60924457
12MAP3K22.08422877
13PTK2B2.05485992
14ERBB32.03073311
15SMG11.90870504
16STK391.82681315
17BCR1.75493665
18STK241.71191153
19MAPKAPK31.67332354
20STK381.59107358
21WNK41.51311019
22MAPKAPK51.47472896
23MST1R1.45886646
24IRAK11.39716429
25MUSK1.33466794
26PHKG11.27376593
27PHKG21.27376593
28EPHB11.26693318
29CSK1.25446940
30PAK31.21424843
31TYRO31.20278327
32DAPK21.20013057
33DYRK1B1.19697192
34GRK11.18836122
35MAP3K31.18119907
36DYRK31.17869616
37STK161.14420377
38PLK41.14276362
39LRRK20.99696751
40EPHA30.97684219
41TLK10.97633219
42MAP3K70.95852494
43STK38L0.95187871
44RPS6KA20.93882911
45PRKCG0.92661151
46CAMK1G0.90212068
47PRKCI0.87478527
48CAMK2B0.86996099
49MAP2K20.82963349
50INSRR0.79705670
51CAMK2D0.78186534
52TRPM70.77857498
53BRSK20.74659373
54MST40.73848189
55IRAK20.72273819
56MAP3K40.71761145
57CDK190.69580707
58CAMK2G0.67885340
59PDK10.66233419
60WNK10.64809818
61MAP2K70.63651683
62TNK20.62559319
63CAMKK20.62248663
64NLK0.59654182
65DYRK1A0.59551879
66NTRK20.57049719
67MAP3K120.54128483
68PLK10.50976716
69CAMKK10.50476558
70CDC42BPA0.50289342
71AURKA0.45838278
72TGFBR20.44385640
73ARAF0.44334632
74LMTK20.44016023
75CASK0.43591448
76PRKCD0.41947508
77MAP4K20.41853017
78GRK50.40861324
79PAK20.38166664
80SGK10.37861074
81TBK10.37581316
82CAMK2A0.37458521
83PRKCQ0.35163430
84TTK0.34823288
85PBK0.34005846
86MAPK130.33302766
87PDPK10.31868481
88LATS10.31767780
89PAK10.31567457
90PRKG20.30410065
91PKN10.30368672
92MARK20.29613103
93CDK30.29582438
94PRKAA20.28164090
95OXSR10.28001081
96MET0.27864630
97RPS6KA10.27596719
98MYLK0.27444763
99ADRBK20.27154881
100PASK0.27107922
101BMPR20.26572173
102NEK20.26386743
103NEK60.26306226
104RPS6KB20.25697114
105ADRBK10.25462875
106PINK10.25304997
107CSNK1G10.24720691
108GSK3A0.24366579
109BMPR1B0.23567098
110MAPK120.23010846
111FER0.22633932
112CHEK20.22471072
113MARK10.22026872
114MAPKAPK20.22004682
115PRKACG0.21418999
116DYRK20.20597484
117HIPK20.20519676
118STK110.20412390
119PAK40.20264823
120EGFR0.19953949
121PRKCZ0.19890063
122PRKAA10.19599645
123ROCK10.16893453
124MAP2K40.16865736
125DDR20.15543709
126RIPK40.14669724
127SRC0.14640863
128PRKACA0.14508768
129FYN0.14228989
130ABL10.13868999
131MINK10.13677578
132ROCK20.13614635
133PRKDC0.13492526
134PRKG10.13431880
135MAP2K60.12084585
136CSNK1E0.11967342
137STK30.11641875
138ERBB20.11284595
139PRKCA0.11129541
140DAPK10.10752810
141RPS6KC10.10275025
142RPS6KL10.10275025
143WEE10.09696389
144GRK60.08673288
145STK100.08612970
146RPS6KA30.08379846
147SGK2230.08088520
148SGK4940.08088520

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047408.02833128
2Phenylalanine metabolism_Homo sapiens_hsa003605.11399484
3Tyrosine metabolism_Homo sapiens_hsa003504.02289531
4beta-Alanine metabolism_Homo sapiens_hsa004102.97471763
5Fatty acid biosynthesis_Homo sapiens_hsa000612.91216021
6Phototransduction_Homo sapiens_hsa047442.74280192
7Retinol metabolism_Homo sapiens_hsa008302.46168751
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.38703510
9Caffeine metabolism_Homo sapiens_hsa002322.33491630
10Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.19643542
11Vitamin B6 metabolism_Homo sapiens_hsa007502.00124416
12Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.89475592
13Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.86159669
14Ovarian steroidogenesis_Homo sapiens_hsa049131.84894798
15Amphetamine addiction_Homo sapiens_hsa050311.79264922
16Insulin secretion_Homo sapiens_hsa049111.77898744
17Pyruvate metabolism_Homo sapiens_hsa006201.77480710
18Glucagon signaling pathway_Homo sapiens_hsa049221.72002052
19Taste transduction_Homo sapiens_hsa047421.71629468
20cAMP signaling pathway_Homo sapiens_hsa040241.62052226
21Dorso-ventral axis formation_Homo sapiens_hsa043201.57847998
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.56498215
23Histidine metabolism_Homo sapiens_hsa003401.56410801
24Gastric acid secretion_Homo sapiens_hsa049711.56265224
25Circadian entrainment_Homo sapiens_hsa047131.52937335
26Propanoate metabolism_Homo sapiens_hsa006401.47092731
27Tight junction_Homo sapiens_hsa045301.45901304
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.44789109
29Salivary secretion_Homo sapiens_hsa049701.44768123
30Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.39952929
31Huntingtons disease_Homo sapiens_hsa050161.38262242
32Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.37016979
33alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.33680148
34cGMP-PKG signaling pathway_Homo sapiens_hsa040221.32743465
35Thyroid hormone synthesis_Homo sapiens_hsa049181.31901388
36PPAR signaling pathway_Homo sapiens_hsa033201.31135884
37Linoleic acid metabolism_Homo sapiens_hsa005911.27242006
38Morphine addiction_Homo sapiens_hsa050321.25551092
39Estrogen signaling pathway_Homo sapiens_hsa049151.25542292
40Renin secretion_Homo sapiens_hsa049241.24163895
41Calcium signaling pathway_Homo sapiens_hsa040201.23699304
42Carbohydrate digestion and absorption_Homo sapiens_hsa049731.23673490
43Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12371090
44Purine metabolism_Homo sapiens_hsa002301.11600459
45Bile secretion_Homo sapiens_hsa049761.11290756
46Peroxisome_Homo sapiens_hsa041461.08433586
47Glycerolipid metabolism_Homo sapiens_hsa005611.06206077
48Glutamatergic synapse_Homo sapiens_hsa047241.02689445
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.98505673
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.97176849
51Cardiac muscle contraction_Homo sapiens_hsa042600.97139312
52Oocyte meiosis_Homo sapiens_hsa041140.92322893
53Cocaine addiction_Homo sapiens_hsa050300.91454575
54Ether lipid metabolism_Homo sapiens_hsa005650.89488618
55Collecting duct acid secretion_Homo sapiens_hsa049660.88593345
56Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88439915
57Starch and sucrose metabolism_Homo sapiens_hsa005000.88156194
58Nicotine addiction_Homo sapiens_hsa050330.85811322
59Mineral absorption_Homo sapiens_hsa049780.85510233
60GABAergic synapse_Homo sapiens_hsa047270.84039096
61Hedgehog signaling pathway_Homo sapiens_hsa043400.83466408
62Glycerophospholipid metabolism_Homo sapiens_hsa005640.82416012
63Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.79121269
64Dopaminergic synapse_Homo sapiens_hsa047280.78438478
65Drug metabolism - other enzymes_Homo sapiens_hsa009830.77757468
66Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77233463
67Long-term potentiation_Homo sapiens_hsa047200.75378877
68Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.74873336
69Arachidonic acid metabolism_Homo sapiens_hsa005900.74195649
70Basal cell carcinoma_Homo sapiens_hsa052170.73598212
71Synaptic vesicle cycle_Homo sapiens_hsa047210.72839410
72Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72627880
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.71034087
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.69166579
75ABC transporters_Homo sapiens_hsa020100.68553709
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.67458877
77Vibrio cholerae infection_Homo sapiens_hsa051100.66905540
78Pancreatic secretion_Homo sapiens_hsa049720.66156417
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65987148
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65975899
81Alcoholism_Homo sapiens_hsa050340.65621257
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63672493
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.62960629
84Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.62294201
85Oxytocin signaling pathway_Homo sapiens_hsa049210.60221063
86Melanogenesis_Homo sapiens_hsa049160.59223509
87Notch signaling pathway_Homo sapiens_hsa043300.58513555
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58365333
89Circadian rhythm_Homo sapiens_hsa047100.58148273
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57850660
91Cyanoamino acid metabolism_Homo sapiens_hsa004600.56838516
92Glycosaminoglycan degradation_Homo sapiens_hsa005310.55653156
93GnRH signaling pathway_Homo sapiens_hsa049120.54476074
94Cholinergic synapse_Homo sapiens_hsa047250.52846934
95Systemic lupus erythematosus_Homo sapiens_hsa053220.52606250
96Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50317248
97Adherens junction_Homo sapiens_hsa045200.50197167
98Arginine and proline metabolism_Homo sapiens_hsa003300.49058326
99Fanconi anemia pathway_Homo sapiens_hsa034600.47794238
100Metabolic pathways_Homo sapiens_hsa011000.46620154
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.45340848
102Fatty acid degradation_Homo sapiens_hsa000710.44989056
103Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.44980158
104Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.44703443
105Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43190170
106Choline metabolism in cancer_Homo sapiens_hsa052310.43177075
107Butanoate metabolism_Homo sapiens_hsa006500.43069968
108Serotonergic synapse_Homo sapiens_hsa047260.41317783
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.40299005
110Hippo signaling pathway_Homo sapiens_hsa043900.38719461
111Glutathione metabolism_Homo sapiens_hsa004800.38016063
112Sphingolipid metabolism_Homo sapiens_hsa006000.37553825
113Primary bile acid biosynthesis_Homo sapiens_hsa001200.36840097
114Chemical carcinogenesis_Homo sapiens_hsa052040.36133822
115Carbon metabolism_Homo sapiens_hsa012000.35984816
116Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32464729
117Vitamin digestion and absorption_Homo sapiens_hsa049770.32233870
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.31814735
119Fat digestion and absorption_Homo sapiens_hsa049750.31814596
120Regulation of autophagy_Homo sapiens_hsa041400.30629485
121Inositol phosphate metabolism_Homo sapiens_hsa005620.30482732
122Gap junction_Homo sapiens_hsa045400.30059754
123Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29293255
124Wnt signaling pathway_Homo sapiens_hsa043100.28418654
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27067867
126Cysteine and methionine metabolism_Homo sapiens_hsa002700.26446647
127Basal transcription factors_Homo sapiens_hsa030220.26325142
128Hepatitis C_Homo sapiens_hsa051600.25954986
129Axon guidance_Homo sapiens_hsa043600.25282477
130Antigen processing and presentation_Homo sapiens_hsa046120.24729650
131Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.23796481
132Pentose phosphate pathway_Homo sapiens_hsa000300.23658076
133AMPK signaling pathway_Homo sapiens_hsa041520.23649862
134Steroid biosynthesis_Homo sapiens_hsa001000.22880085
135Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.22693614
136Hematopoietic cell lineage_Homo sapiens_hsa046400.21480640
137Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20573825
138Tryptophan metabolism_Homo sapiens_hsa003800.20121472
139Nucleotide excision repair_Homo sapiens_hsa034200.13314200
140Oxidative phosphorylation_Homo sapiens_hsa001900.12386475
141Complement and coagulation cascades_Homo sapiens_hsa046100.12305599
142Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.11613910
143Arginine biosynthesis_Homo sapiens_hsa002200.10335601
144Nitrogen metabolism_Homo sapiens_hsa009100.09305549
145Endocytosis_Homo sapiens_hsa041440.07983627
146Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.06858768
147p53 signaling pathway_Homo sapiens_hsa041150.04517661

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