Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit biogenesis (GO:0042274) | 5.01890080 |
2 | proteasome assembly (GO:0043248) | 4.51737981 |
3 | termination of RNA polymerase III transcription (GO:0006386) | 4.37539246 |
4 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.37539246 |
5 | ribosomal small subunit assembly (GO:0000028) | 4.31688164 |
6 | viral transcription (GO:0019083) | 4.20163710 |
7 | translational termination (GO:0006415) | 4.13782176 |
8 | maturation of SSU-rRNA (GO:0030490) | 4.10544178 |
9 | cotranslational protein targeting to membrane (GO:0006613) | 4.07715577 |
10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.06206817 |
11 | RNA capping (GO:0036260) | 4.05481047 |
12 | 7-methylguanosine RNA capping (GO:0009452) | 4.05481047 |
13 | rRNA modification (GO:0000154) | 4.04768648 |
14 | 7-methylguanosine mRNA capping (GO:0006370) | 4.03550684 |
15 | protein targeting to ER (GO:0045047) | 4.00590048 |
16 | ribosomal large subunit biogenesis (GO:0042273) | 3.96050705 |
17 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.94717344 |
18 | protein neddylation (GO:0045116) | 3.91006341 |
19 | histone exchange (GO:0043486) | 3.84593808 |
20 | DNA deamination (GO:0045006) | 3.82084754 |
21 | protein localization to endoplasmic reticulum (GO:0070972) | 3.81272962 |
22 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.80552313 |
23 | termination of RNA polymerase I transcription (GO:0006363) | 3.78120708 |
24 | ribosome assembly (GO:0042255) | 3.68204171 |
25 | centriole replication (GO:0007099) | 3.63409973 |
26 | transcription from RNA polymerase I promoter (GO:0006360) | 3.60918811 |
27 | respiratory electron transport chain (GO:0022904) | 3.57017310 |
28 | rRNA methylation (GO:0031167) | 3.55824945 |
29 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.54287441 |
30 | DNA replication-independent nucleosome organization (GO:0034724) | 3.54287441 |
31 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.52330035 |
32 | GTP biosynthetic process (GO:0006183) | 3.50053576 |
33 | rRNA processing (GO:0006364) | 3.49838886 |
34 | electron transport chain (GO:0022900) | 3.48743809 |
35 | translation (GO:0006412) | 3.43608070 |
36 | translational initiation (GO:0006413) | 3.43564960 |
37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.42182437 |
38 | establishment of integrated proviral latency (GO:0075713) | 3.42109730 |
39 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.39914513 |
40 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.39410291 |
41 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.38257761 |
42 | rRNA metabolic process (GO:0016072) | 3.37477891 |
43 | viral life cycle (GO:0019058) | 3.36065916 |
44 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.33604964 |
45 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.33321299 |
46 | chaperone-mediated protein transport (GO:0072321) | 3.33199416 |
47 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.32984907 |
48 | translational elongation (GO:0006414) | 3.32289604 |
49 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.31925457 |
50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.29075819 |
51 | cellular protein complex disassembly (GO:0043624) | 3.28167346 |
52 | protein localization to kinetochore (GO:0034501) | 3.27971755 |
53 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.27058132 |
54 | histone mRNA metabolic process (GO:0008334) | 3.25374113 |
55 | DNA strand elongation (GO:0022616) | 3.25352086 |
56 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.24739536 |
57 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.24739536 |
58 | mRNA catabolic process (GO:0006402) | 3.23901766 |
59 | establishment of viral latency (GO:0019043) | 3.23278652 |
60 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.22647497 |
61 | macromolecular complex disassembly (GO:0032984) | 3.21863553 |
62 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.20195077 |
63 | ATP synthesis coupled proton transport (GO:0015986) | 3.20195077 |
64 | telomere maintenance via recombination (GO:0000722) | 3.17757267 |
65 | maturation of 5.8S rRNA (GO:0000460) | 3.17029094 |
66 | protein targeting to mitochondrion (GO:0006626) | 3.16335744 |
67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.15304170 |
68 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.15261554 |
69 | mitotic G2/M transition checkpoint (GO:0044818) | 3.15066218 |
70 | cellular component biogenesis (GO:0044085) | 3.14584771 |
71 | DNA damage response, detection of DNA damage (GO:0042769) | 3.12669654 |
72 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.11984071 |
73 | negative regulation of ligase activity (GO:0051352) | 3.11984071 |
74 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.11648710 |
75 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.11069488 |
76 | protein localization to mitochondrion (GO:0070585) | 3.09487413 |
77 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 3.07944673 |
78 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.07452361 |
79 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.06957981 |
80 | UTP biosynthetic process (GO:0006228) | 3.06865969 |
81 | RNA catabolic process (GO:0006401) | 3.05622113 |
82 | respiratory chain complex IV assembly (GO:0008535) | 3.05518552 |
83 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.04898223 |
84 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.04898223 |
85 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.04898223 |
86 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.04525808 |
87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.04408030 |
88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.04408030 |
89 | metaphase plate congression (GO:0051310) | 3.03322403 |
90 | establishment of protein localization to mitochondrion (GO:0072655) | 3.01917553 |
91 | replication fork processing (GO:0031297) | 3.01793049 |
92 | regulation of mitochondrial translation (GO:0070129) | 3.00686784 |
93 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.99988385 |
94 | pseudouridine synthesis (GO:0001522) | 2.99573955 |
95 | mitotic recombination (GO:0006312) | 2.99203845 |
96 | DNA-templated transcription, elongation (GO:0006354) | 2.98159514 |
97 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.97617533 |
98 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.97561408 |
99 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.97561408 |
100 | NADH dehydrogenase complex assembly (GO:0010257) | 2.97561408 |
101 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.97428408 |
102 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.95998754 |
103 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.95945833 |
104 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.95945833 |
105 | spliceosomal snRNP assembly (GO:0000387) | 2.95569762 |
106 | positive regulation of viral transcription (GO:0050434) | 2.95044933 |
107 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.93341852 |
108 | spliceosomal complex assembly (GO:0000245) | 2.93335585 |
109 | protein localization to chromosome, centromeric region (GO:0071459) | 2.92667935 |
110 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.92297618 |
111 | CENP-A containing nucleosome assembly (GO:0034080) | 2.92169566 |
112 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.91892234 |
113 | inner mitochondrial membrane organization (GO:0007007) | 2.91000489 |
114 | protein targeting to membrane (GO:0006612) | 2.90129564 |
115 | base-excision repair, AP site formation (GO:0006285) | 2.89979356 |
116 | organelle disassembly (GO:1903008) | 2.89031153 |
117 | cullin deneddylation (GO:0010388) | 2.88707473 |
118 | kinetochore assembly (GO:0051382) | 2.88447576 |
119 | kinetochore organization (GO:0051383) | 2.87239484 |
120 | peptidyl-histidine modification (GO:0018202) | 2.86560300 |
121 | mitotic metaphase plate congression (GO:0007080) | 2.86211086 |
122 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.79260181 |
123 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.78408024 |
124 | protein complex biogenesis (GO:0070271) | 2.77444747 |
125 | mannosylation (GO:0097502) | 2.75897951 |
126 | formation of translation preinitiation complex (GO:0001731) | 2.72929625 |
127 | positive regulation of ligase activity (GO:0051351) | 2.72837429 |
128 | ribosome biogenesis (GO:0042254) | 2.72823636 |
129 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.72612139 |
130 | protein complex disassembly (GO:0043241) | 2.72008841 |
131 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.71888200 |
132 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.71888200 |
133 | chromatin remodeling at centromere (GO:0031055) | 2.71851156 |
134 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.71760918 |
135 | DNA-templated transcription, termination (GO:0006353) | 2.70064538 |
136 | DNA replication initiation (GO:0006270) | 2.67727753 |
137 | DNA replication checkpoint (GO:0000076) | 2.66475172 |
138 | ncRNA processing (GO:0034470) | 2.66397234 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.63853665 |
2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.49919957 |
3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.37242635 |
4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.36852109 |
5 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.03240751 |
6 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.97702056 |
7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.54941096 |
8 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.50413346 |
9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.46937711 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.35863445 |
11 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.32183613 |
12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.18929773 |
13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.09537946 |
14 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.08236483 |
15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.78882388 |
16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.73262733 |
17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.70883755 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.67964548 |
19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.59400946 |
20 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.55246967 |
21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.55128833 |
22 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.42919119 |
23 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.40855177 |
24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.23190708 |
25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.22548808 |
26 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.15396804 |
27 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.11968762 |
28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.11135267 |
29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.02172043 |
30 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.01604315 |
31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.98021641 |
32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.96767768 |
33 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.94694245 |
34 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.90153179 |
35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.89841880 |
36 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.83463493 |
37 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.79971370 |
38 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.78212149 |
39 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.77028825 |
40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.76763769 |
41 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.73349117 |
42 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.68569465 |
43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.66922951 |
44 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.61802685 |
45 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.59117626 |
46 | * PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56268804 |
47 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.55451853 |
48 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.54935695 |
49 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.42803333 |
50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37536717 |
51 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.36438472 |
52 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.36367486 |
53 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31742821 |
54 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.31003368 |
55 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.30037175 |
56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.28110229 |
57 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.27949866 |
58 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.27033121 |
59 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.22212583 |
60 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.21260380 |
61 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.20639973 |
62 | VDR_22108803_ChIP-Seq_LS180_Human | 1.20517591 |
63 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.19913402 |
64 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19799076 |
65 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.17696372 |
66 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15542767 |
67 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.15426322 |
68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14851908 |
69 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14153494 |
70 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.13071954 |
71 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10349415 |
72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09050225 |
73 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.08134313 |
74 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.07676476 |
75 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05378293 |
76 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.04645887 |
77 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.01322153 |
78 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.00822899 |
79 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.00673481 |
80 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.99830931 |
81 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.99684728 |
82 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.98983965 |
83 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.98453555 |
84 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98444802 |
85 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94423299 |
86 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94276182 |
87 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.92954350 |
88 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.91337061 |
89 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.90999296 |
90 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.89192488 |
91 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.87759959 |
92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87732253 |
93 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.86869989 |
94 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.86549607 |
95 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.83042562 |
96 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.82721915 |
97 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.82709214 |
98 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.82576435 |
99 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.82537305 |
100 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.82500925 |
101 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.81230395 |
102 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.80886922 |
103 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.80861033 |
104 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.79808402 |
105 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.78099775 |
106 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.78099775 |
107 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.78099775 |
108 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.77918588 |
109 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.77884176 |
110 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.77575495 |
111 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.77101507 |
112 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.76489230 |
113 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.75772528 |
114 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.74322100 |
115 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.73191419 |
116 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.71438691 |
117 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.70011145 |
118 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.68466598 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.90993640 |
2 | MP0008057_abnormal_DNA_replication | 3.53381987 |
3 | MP0003136_yellow_coat_color | 3.26527314 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.07626213 |
5 | MP0009379_abnormal_foot_pigmentation | 2.99155053 |
6 | MP0008058_abnormal_DNA_repair | 2.69469838 |
7 | MP0008932_abnormal_embryonic_tissue | 2.50056490 |
8 | MP0010094_abnormal_chromosome_stability | 2.30804016 |
9 | MP0001188_hyperpigmentation | 2.28474129 |
10 | MP0003111_abnormal_nucleus_morphology | 2.28183616 |
11 | MP0001529_abnormal_vocalization | 2.23245674 |
12 | MP0003077_abnormal_cell_cycle | 2.22541427 |
13 | MP0002163_abnormal_gland_morphology | 2.14487249 |
14 | MP0003806_abnormal_nucleotide_metabolis | 2.11578186 |
15 | MP0002277_abnormal_respiratory_mucosa | 2.10926355 |
16 | MP0006292_abnormal_olfactory_placode | 2.08195050 |
17 | MP0005379_endocrine/exocrine_gland_phen | 2.01993742 |
18 | MP0008007_abnormal_cellular_replicative | 1.91820783 |
19 | MP0003941_abnormal_skin_development | 1.88099454 |
20 | MP0008995_early_reproductive_senescence | 1.87152448 |
21 | MP0003718_maternal_effect | 1.86451931 |
22 | MP0003890_abnormal_embryonic-extraembry | 1.83508701 |
23 | MP0000372_irregular_coat_pigmentation | 1.75949024 |
24 | MP0002210_abnormal_sex_determination | 1.74295906 |
25 | MP0006036_abnormal_mitochondrial_physio | 1.64301614 |
26 | MP0005671_abnormal_response_to | 1.63727917 |
27 | MP0001929_abnormal_gametogenesis | 1.63556894 |
28 | MP0005409_darkened_coat_color | 1.61258134 |
29 | MP0002132_abnormal_respiratory_system | 1.60891453 |
30 | MP0006072_abnormal_retinal_apoptosis | 1.58605858 |
31 | MP0009697_abnormal_copulation | 1.57604371 |
32 | MP0004381_abnormal_hair_follicle | 1.53344353 |
33 | MP0001485_abnormal_pinna_reflex | 1.52250581 |
34 | MP0001905_abnormal_dopamine_level | 1.48670070 |
35 | MP0002638_abnormal_pupillary_reflex | 1.46473555 |
36 | MP0006035_abnormal_mitochondrial_morpho | 1.44341274 |
37 | MP0005171_absent_coat_pigmentation | 1.43350480 |
38 | MP0002938_white_spotting | 1.43019308 |
39 | MP0002102_abnormal_ear_morphology | 1.39688666 |
40 | MP0001145_abnormal_male_reproductive | 1.38827725 |
41 | MP0002148_abnormal_hypersensitivity_rea | 1.37398911 |
42 | MP0000015_abnormal_ear_pigmentation | 1.37260725 |
43 | MP0001764_abnormal_homeostasis | 1.35510445 |
44 | MP0000631_abnormal_neuroendocrine_gland | 1.35360439 |
45 | MP0000653_abnormal_sex_gland | 1.33049758 |
46 | MP0009333_abnormal_splenocyte_physiolog | 1.32386770 |
47 | MP0002234_abnormal_pharynx_morphology | 1.32024465 |
48 | MP0003121_genomic_imprinting | 1.31819730 |
49 | MP0003786_premature_aging | 1.31642723 |
50 | MP0003950_abnormal_plasma_membrane | 1.27708902 |
51 | MP0008260_abnormal_autophagy | 1.26518811 |
52 | MP0003567_abnormal_fetal_cardiomyocyte | 1.26036354 |
53 | MP0001835_abnormal_antigen_presentation | 1.23749111 |
54 | MP0004147_increased_porphyrin_level | 1.21443990 |
55 | MP0003315_abnormal_perineum_morphology | 1.21404929 |
56 | MP0009785_altered_susceptibility_to | 1.20754363 |
57 | MP0005410_abnormal_fertilization | 1.18729502 |
58 | MP0001697_abnormal_embryo_size | 1.18649047 |
59 | MP0003880_abnormal_central_pattern | 1.16273469 |
60 | MP0001919_abnormal_reproductive_system | 1.15733494 |
61 | MP0003186_abnormal_redox_activity | 1.15500342 |
62 | MP0003763_abnormal_thymus_physiology | 1.15489638 |
63 | MP0003195_calcinosis | 1.10565936 |
64 | MP0005646_abnormal_pituitary_gland | 1.07223911 |
65 | MP0004742_abnormal_vestibular_system | 1.06704944 |
66 | MP0003698_abnormal_male_reproductive | 1.06202587 |
67 | MP0005000_abnormal_immune_tolerance | 1.05560906 |
68 | MP0005075_abnormal_melanosome_morpholog | 1.04562898 |
69 | MP0000678_abnormal_parathyroid_gland | 1.04309336 |
70 | MP0000350_abnormal_cell_proliferation | 1.03758889 |
71 | MP0005394_taste/olfaction_phenotype | 1.02479389 |
72 | MP0005499_abnormal_olfactory_system | 1.02479389 |
73 | MP0002160_abnormal_reproductive_system | 1.00900538 |
74 | MP0003787_abnormal_imprinting | 1.00677239 |
75 | MP0002751_abnormal_autonomic_nervous | 1.00082854 |
76 | MP0003938_abnormal_ear_development | 0.99800200 |
77 | MP0000566_synostosis | 0.99743691 |
78 | MP0001542_abnormal_bone_strength | 0.99354869 |
79 | MP0005408_hypopigmentation | 0.98656053 |
80 | MP0000613_abnormal_salivary_gland | 0.98585730 |
81 | MP0003724_increased_susceptibility_to | 0.98030032 |
82 | MP0004142_abnormal_muscle_tone | 0.97987869 |
83 | MP0002723_abnormal_immune_serum | 0.96755476 |
84 | MP0002095_abnormal_skin_pigmentation | 0.96105040 |
85 | MP0002019_abnormal_tumor_incidence | 0.95903000 |
86 | MP0001672_abnormal_embryogenesis/_devel | 0.95745517 |
87 | MP0005380_embryogenesis_phenotype | 0.95745517 |
88 | MP0005266_abnormal_metabolism | 0.94555791 |
89 | MP0005395_other_phenotype | 0.94276755 |
90 | MP0002452_abnormal_antigen_presenting | 0.93567860 |
91 | MP0000049_abnormal_middle_ear | 0.93045089 |
92 | MP0005084_abnormal_gallbladder_morpholo | 0.92689674 |
93 | MP0000703_abnormal_thymus_morphology | 0.92347867 |
94 | MP0004133_heterotaxia | 0.92019905 |
95 | MP0002420_abnormal_adaptive_immunity | 0.91429174 |
96 | MP0001819_abnormal_immune_cell | 0.91066652 |
97 | MP0001800_abnormal_humoral_immune | 0.90682971 |
98 | MP0005174_abnormal_tail_pigmentation | 0.89885193 |
99 | MP0005387_immune_system_phenotype | 0.89679948 |
100 | MP0001790_abnormal_immune_system | 0.89679948 |
101 | MP0000026_abnormal_inner_ear | 0.88476049 |
102 | MP0001853_heart_inflammation | 0.87651196 |
103 | MP0008877_abnormal_DNA_methylation | 0.87511922 |
104 | MP0008789_abnormal_olfactory_epithelium | 0.87367236 |
105 | MP0001119_abnormal_female_reproductive | 0.87337205 |
106 | MP0002396_abnormal_hematopoietic_system | 0.86757018 |
107 | MP0010307_abnormal_tumor_latency | 0.86695322 |
108 | MP0000313_abnormal_cell_death | 0.85557079 |
109 | MP0005389_reproductive_system_phenotype | 0.85456118 |
110 | MP0002084_abnormal_developmental_patter | 0.84482327 |
111 | MP0000858_altered_metastatic_potential | 0.83409708 |
112 | MP0005253_abnormal_eye_physiology | 0.83366058 |
113 | MP0001986_abnormal_taste_sensitivity | 0.83322038 |
114 | MP0003656_abnormal_erythrocyte_physiolo | 0.82402662 |
115 | MP0002085_abnormal_embryonic_tissue | 0.81777512 |
116 | MP0002080_prenatal_lethality | 0.81755884 |
117 | MP0002398_abnormal_bone_marrow | 0.81429182 |
118 | MP0001293_anophthalmia | 0.81251744 |
119 | MP0006082_CNS_inflammation | 0.80999745 |
120 | MP0003123_paternal_imprinting | 0.80962573 |
121 | MP0002161_abnormal_fertility/fecundity | 0.80869244 |
122 | MP0005551_abnormal_eye_electrophysiolog | 0.80250285 |
123 | MP0005025_abnormal_response_to | 0.80069104 |
124 | MP0003699_abnormal_female_reproductive | 0.79961887 |
125 | MP0000358_abnormal_cell_content/ | 0.79573842 |
126 | MP0003984_embryonic_growth_retardation | 0.77492152 |
127 | MP0003937_abnormal_limbs/digits/tail_de | 0.77161381 |
128 | MP0001286_abnormal_eye_development | 0.75754614 |
129 | MP0002088_abnormal_embryonic_growth/wei | 0.75366953 |
130 | MP0001730_embryonic_growth_arrest | 0.74171844 |
131 | MP0000716_abnormal_immune_system | 0.73952991 |
132 | MP0001963_abnormal_hearing_physiology | 0.73674630 |
133 | MP0000490_abnormal_crypts_of | 0.73359794 |
134 | MP0002177_abnormal_outer_ear | 0.71262587 |
135 | MP0002722_abnormal_immune_system | 0.70354623 |
136 | MP0002419_abnormal_innate_immunity | 0.70349464 |
137 | MP0004197_abnormal_fetal_growth/weight/ | 0.69627074 |
138 | MP0000920_abnormal_myelination | 0.68743073 |
139 | MP0000689_abnormal_spleen_morphology | 0.68453524 |
140 | MP0010030_abnormal_orbit_morphology | 0.67879879 |
141 | MP0008961_abnormal_basal_metabolism | 0.67647922 |
142 | MP0003936_abnormal_reproductive_system | 0.66055457 |
143 | MP0002405_respiratory_system_inflammati | 0.65440435 |
144 | MP0002429_abnormal_blood_cell | 0.64842102 |
145 | MP0005391_vision/eye_phenotype | 0.61595058 |
146 | MP0000427_abnormal_hair_cycle | 0.59681291 |
147 | MP0003119_abnormal_digestive_system | 0.56784310 |
148 | MP0001324_abnormal_eye_pigmentation | 0.56085165 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 4.11191939 |
2 | Acute necrotizing encephalopathy (HP:0006965) | 3.96612526 |
3 | Mitochondrial inheritance (HP:0001427) | 3.54811333 |
4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.31849420 |
5 | Increased hepatocellular lipid droplets (HP:0006565) | 3.31277351 |
6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.28132135 |
7 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.23084889 |
8 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.22399885 |
9 | Reticulocytopenia (HP:0001896) | 3.21172272 |
10 | Progressive macrocephaly (HP:0004481) | 3.18075114 |
11 | Abnormal number of erythroid precursors (HP:0012131) | 3.15794795 |
12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.03366212 |
13 | Cerebral edema (HP:0002181) | 3.00765230 |
14 | Parakeratosis (HP:0001036) | 2.99010390 |
15 | Increased CSF lactate (HP:0002490) | 2.96644353 |
16 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.95374451 |
17 | Hepatocellular necrosis (HP:0001404) | 2.91805777 |
18 | Renal Fanconi syndrome (HP:0001994) | 2.88177911 |
19 | Acute encephalopathy (HP:0006846) | 2.84172253 |
20 | Breast hypoplasia (HP:0003187) | 2.83179281 |
21 | Increased intramyocellular lipid droplets (HP:0012240) | 2.80807002 |
22 | Macrocytic anemia (HP:0001972) | 2.72690635 |
23 | Type I transferrin isoform profile (HP:0003642) | 2.72306454 |
24 | Cerebral hypomyelination (HP:0006808) | 2.70569978 |
25 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.60326403 |
26 | Exertional dyspnea (HP:0002875) | 2.55467165 |
27 | Volvulus (HP:0002580) | 2.53266523 |
28 | Methylmalonic acidemia (HP:0002912) | 2.49877071 |
29 | Lipid accumulation in hepatocytes (HP:0006561) | 2.49299574 |
30 | Methylmalonic aciduria (HP:0012120) | 2.47288241 |
31 | Oral leukoplakia (HP:0002745) | 2.46364464 |
32 | Medial flaring of the eyebrow (HP:0010747) | 2.43647364 |
33 | Chronic hepatic failure (HP:0100626) | 2.43570549 |
34 | Rough bone trabeculation (HP:0100670) | 2.42618309 |
35 | Lactic acidosis (HP:0003128) | 2.42361330 |
36 | Stenosis of the external auditory canal (HP:0000402) | 2.41410095 |
37 | Pallor (HP:0000980) | 2.38691853 |
38 | Supernumerary spleens (HP:0009799) | 2.38650057 |
39 | True hermaphroditism (HP:0010459) | 2.34298079 |
40 | Abnormality of the pons (HP:0007361) | 2.33762172 |
41 | Irregular epiphyses (HP:0010582) | 2.32550588 |
42 | Adrenal hypoplasia (HP:0000835) | 2.32085528 |
43 | Pancreatic fibrosis (HP:0100732) | 2.30740355 |
44 | Congenital, generalized hypertrichosis (HP:0004540) | 2.28141436 |
45 | Cleft eyelid (HP:0000625) | 2.26680237 |
46 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.25121649 |
47 | Premature ovarian failure (HP:0008209) | 2.24455406 |
48 | Pancreatic cysts (HP:0001737) | 2.23496812 |
49 | Increased muscle lipid content (HP:0009058) | 2.22768437 |
50 | Small epiphyses (HP:0010585) | 2.21014376 |
51 | Increased serum pyruvate (HP:0003542) | 2.20799054 |
52 | Abnormality of glycolysis (HP:0004366) | 2.20799054 |
53 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.20037889 |
54 | Abnormality of the preputium (HP:0100587) | 2.19939381 |
55 | Colon cancer (HP:0003003) | 2.18244871 |
56 | Increased serum lactate (HP:0002151) | 2.17969580 |
57 | Respiratory difficulties (HP:0002880) | 2.16311235 |
58 | Hepatic necrosis (HP:0002605) | 2.15546493 |
59 | Congenital primary aphakia (HP:0007707) | 2.15274272 |
60 | Abnormal trabecular bone morphology (HP:0100671) | 2.15201090 |
61 | Leukodystrophy (HP:0002415) | 2.14992275 |
62 | Optic disc pallor (HP:0000543) | 2.14407911 |
63 | Chromsome breakage (HP:0040012) | 2.14054164 |
64 | Hypoplasia of the pons (HP:0012110) | 2.11114577 |
65 | Myelodysplasia (HP:0002863) | 2.11011748 |
66 | Degeneration of anterior horn cells (HP:0002398) | 2.07804754 |
67 | Abnormality of the anterior horn cell (HP:0006802) | 2.07804754 |
68 | Exercise intolerance (HP:0003546) | 2.07701420 |
69 | Pancytopenia (HP:0001876) | 2.07407282 |
70 | Small intestinal stenosis (HP:0012848) | 2.05261910 |
71 | Duodenal stenosis (HP:0100867) | 2.05261910 |
72 | Absent septum pellucidum (HP:0001331) | 2.04727689 |
73 | Nephrogenic diabetes insipidus (HP:0009806) | 2.03514097 |
74 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.03023309 |
75 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.03023309 |
76 | Gait imbalance (HP:0002141) | 2.02002095 |
77 | Abnormality of methionine metabolism (HP:0010901) | 2.01600935 |
78 | Absent thumb (HP:0009777) | 2.01360812 |
79 | Abnormality of the septum pellucidum (HP:0007375) | 2.00626865 |
80 | Reduced antithrombin III activity (HP:0001976) | 2.00608041 |
81 | Patellar aplasia (HP:0006443) | 1.97794586 |
82 | Cupped ear (HP:0000378) | 1.97076983 |
83 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.95503829 |
84 | Oligodactyly (hands) (HP:0001180) | 1.94163079 |
85 | Multiple enchondromatosis (HP:0005701) | 1.93047372 |
86 | Triphalangeal thumb (HP:0001199) | 1.91286745 |
87 | Abnormality of the renal collecting system (HP:0004742) | 1.91115671 |
88 | Homocystinuria (HP:0002156) | 1.90044777 |
89 | Abnormality of homocysteine metabolism (HP:0010919) | 1.90044777 |
90 | Abnormality of renal resorption (HP:0011038) | 1.89392648 |
91 | Meckel diverticulum (HP:0002245) | 1.87719338 |
92 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.87089052 |
93 | Nasolacrimal duct obstruction (HP:0000579) | 1.86678663 |
94 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.86460327 |
95 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.86460327 |
96 | Abnormal protein glycosylation (HP:0012346) | 1.86460327 |
97 | Abnormal glycosylation (HP:0012345) | 1.86460327 |
98 | Abnormality of midbrain morphology (HP:0002418) | 1.85818980 |
99 | Molar tooth sign on MRI (HP:0002419) | 1.85818980 |
100 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.85782934 |
101 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.85537761 |
102 | Megaloblastic anemia (HP:0001889) | 1.85272366 |
103 | Sloping forehead (HP:0000340) | 1.84991150 |
104 | Abnormal hemoglobin (HP:0011902) | 1.83859508 |
105 | Hypoplastic pelvis (HP:0008839) | 1.83585849 |
106 | Respiratory failure (HP:0002878) | 1.82815787 |
107 | Aplastic anemia (HP:0001915) | 1.82492468 |
108 | Sensory axonal neuropathy (HP:0003390) | 1.82322757 |
109 | Intestinal atresia (HP:0011100) | 1.81819112 |
110 | Trismus (HP:0000211) | 1.80020580 |
111 | Secondary amenorrhea (HP:0000869) | 1.79704832 |
112 | Abnormality of the ileum (HP:0001549) | 1.79638100 |
113 | Abnormal spermatogenesis (HP:0008669) | 1.78347612 |
114 | Anencephaly (HP:0002323) | 1.78340130 |
115 | Abnormal lung lobation (HP:0002101) | 1.78274451 |
116 | Abnormality of chromosome stability (HP:0003220) | 1.77795596 |
117 | Delayed epiphyseal ossification (HP:0002663) | 1.77794993 |
118 | Prolonged neonatal jaundice (HP:0006579) | 1.77675636 |
119 | Vaginal atresia (HP:0000148) | 1.77342049 |
120 | Abnormality of the duodenum (HP:0002246) | 1.76868992 |
121 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.76614372 |
122 | Absent epiphyses (HP:0010577) | 1.76614372 |
123 | Gonadotropin excess (HP:0000837) | 1.74697062 |
124 | Flat capital femoral epiphysis (HP:0003370) | 1.72940035 |
125 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.71930086 |
126 | Abnormal hair whorl (HP:0010721) | 1.71414543 |
127 | Duplicated collecting system (HP:0000081) | 1.70922137 |
128 | Conical tooth (HP:0000698) | 1.69538189 |
129 | Abnormality of the labia minora (HP:0012880) | 1.69091513 |
130 | Azoospermia (HP:0000027) | 1.68760162 |
131 | Microvesicular hepatic steatosis (HP:0001414) | 1.68327568 |
132 | Lethargy (HP:0001254) | 1.68320133 |
133 | Septo-optic dysplasia (HP:0100842) | 1.68101583 |
134 | Genital tract atresia (HP:0001827) | 1.67887818 |
135 | Horseshoe kidney (HP:0000085) | 1.67732226 |
136 | Aplasia involving forearm bones (HP:0009822) | 1.66863001 |
137 | Absent forearm bone (HP:0003953) | 1.66863001 |
138 | Absent radius (HP:0003974) | 1.66481448 |
139 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.66359743 |
140 | Sclerocornea (HP:0000647) | 1.66326003 |
141 | Asplenia (HP:0001746) | 1.65968900 |
142 | Glycosuria (HP:0003076) | 1.65611087 |
143 | Abnormality of urine glucose concentration (HP:0011016) | 1.65611087 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PBK | 3.78192852 |
2 | BUB1 | 2.98225233 |
3 | EIF2AK3 | 2.94045042 |
4 | STK16 | 2.92546194 |
5 | VRK2 | 2.74079238 |
6 | EIF2AK1 | 2.71154488 |
7 | MKNK1 | 2.52727476 |
8 | SRPK1 | 2.46558520 |
9 | VRK1 | 2.33355716 |
10 | PIM2 | 2.22708695 |
11 | CASK | 2.20347207 |
12 | MKNK2 | 2.19814646 |
13 | TLK1 | 2.11714247 |
14 | NME1 | 2.08424784 |
15 | WEE1 | 2.05418373 |
16 | NME2 | 2.02817644 |
17 | MST4 | 1.88902420 |
18 | IRAK4 | 1.84223073 |
19 | NEK1 | 1.81956500 |
20 | INSRR | 1.81089992 |
21 | TESK2 | 1.80307045 |
22 | PLK4 | 1.74046141 |
23 | TXK | 1.69534252 |
24 | IRAK3 | 1.64273762 |
25 | TSSK6 | 1.62757079 |
26 | EIF2AK2 | 1.56363558 |
27 | PNCK | 1.53761824 |
28 | WNK3 | 1.50698614 |
29 | PLK3 | 1.44010872 |
30 | NEK2 | 1.35697089 |
31 | STK39 | 1.31321149 |
32 | BRSK2 | 1.30941678 |
33 | TNIK | 1.27611312 |
34 | BRAF | 1.24657780 |
35 | BMPR1B | 1.23466548 |
36 | BCR | 1.22513083 |
37 | TAOK3 | 1.17914163 |
38 | RPS6KA5 | 1.12990568 |
39 | PLK1 | 1.11737027 |
40 | CDC7 | 1.08857632 |
41 | BMPR2 | 1.07786336 |
42 | TAF1 | 1.07237766 |
43 | DYRK2 | 1.07141597 |
44 | ADRBK2 | 1.05138428 |
45 | TRIM28 | 1.03351738 |
46 | GRK1 | 1.02195027 |
47 | AURKA | 1.00342953 |
48 | NEK6 | 0.97276376 |
49 | OXSR1 | 0.97084624 |
50 | RPS6KB2 | 0.95598181 |
51 | LATS1 | 0.92042838 |
52 | ZAK | 0.90452150 |
53 | MAPK15 | 0.89286295 |
54 | AURKB | 0.89176222 |
55 | CDK3 | 0.87638001 |
56 | PDK2 | 0.87105931 |
57 | YES1 | 0.86670821 |
58 | IKBKB | 0.86322299 |
59 | PLK2 | 0.83503764 |
60 | DYRK3 | 0.81041097 |
61 | RPS6KA4 | 0.79501877 |
62 | IRAK1 | 0.79238403 |
63 | CDK19 | 0.79053022 |
64 | STK3 | 0.78451910 |
65 | GRK7 | 0.78341122 |
66 | MAP2K2 | 0.76759821 |
67 | MAP3K14 | 0.75638471 |
68 | TEC | 0.75344097 |
69 | ARAF | 0.74572938 |
70 | CDK8 | 0.73391915 |
71 | PASK | 0.73301586 |
72 | MAPKAPK5 | 0.72502953 |
73 | LIMK1 | 0.71833281 |
74 | TTK | 0.71810405 |
75 | CSNK2A1 | 0.71200738 |
76 | MARK3 | 0.70933298 |
77 | MAP3K12 | 0.70792160 |
78 | NUAK1 | 0.66868968 |
79 | CDK7 | 0.64632026 |
80 | BRD4 | 0.64613896 |
81 | CSNK2A2 | 0.62087911 |
82 | CSNK1E | 0.61601170 |
83 | ATR | 0.61375739 |
84 | BRSK1 | 0.60739326 |
85 | KIT | 0.60235857 |
86 | IKBKE | 0.60190753 |
87 | ERBB3 | 0.58490218 |
88 | LYN | 0.57775872 |
89 | EPHA2 | 0.57443328 |
90 | CDK2 | 0.56829387 |
91 | CLK1 | 0.56067864 |
92 | MAP3K4 | 0.56045203 |
93 | STK24 | 0.55410349 |
94 | CDK9 | 0.55169773 |
95 | PKN1 | 0.53897698 |
96 | NLK | 0.50871484 |
97 | ACVR1B | 0.49472788 |
98 | CCNB1 | 0.49431267 |
99 | CHEK2 | 0.45910359 |
100 | CHEK1 | 0.45261675 |
101 | WNK4 | 0.45003791 |
102 | PAK1 | 0.43768777 |
103 | IRAK2 | 0.42718277 |
104 | NEK9 | 0.39748285 |
105 | ATM | 0.39455426 |
106 | LCK | 0.39381004 |
107 | STK4 | 0.38726128 |
108 | AKT3 | 0.37537160 |
109 | FGR | 0.37516381 |
110 | SIK3 | 0.37166059 |
111 | CAMK2B | 0.37051005 |
112 | PRKCI | 0.36947030 |
113 | ABL2 | 0.35771563 |
114 | PIM1 | 0.35747927 |
115 | STK38L | 0.35096816 |
116 | PIK3CA | 0.34945957 |
117 | BLK | 0.34374641 |
118 | MAP4K2 | 0.34214585 |
119 | CDK1 | 0.34133679 |
120 | CDK4 | 0.34096949 |
121 | CSNK1G1 | 0.33180627 |
122 | MAPK13 | 0.32581450 |
123 | MAP2K7 | 0.32237987 |
124 | FRK | 0.30918504 |
125 | ALK | 0.30743001 |
126 | PIK3CG | 0.30328983 |
127 | TGFBR1 | 0.28620349 |
128 | PRKACB | 0.27100116 |
129 | STK10 | 0.24871926 |
130 | BCKDK | 0.24764338 |
131 | CSNK1G2 | 0.24614827 |
132 | CHUK | 0.24034207 |
133 | PRKCG | 0.23910122 |
134 | CSNK1G3 | 0.23487187 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.26873492 |
2 | Proteasome_Homo sapiens_hsa03050 | 3.89182883 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 3.87583645 |
4 | Protein export_Homo sapiens_hsa03060 | 3.32957066 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.76231847 |
6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.71900476 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.60667387 |
8 | DNA replication_Homo sapiens_hsa03030 | 2.54221325 |
9 | Mismatch repair_Homo sapiens_hsa03430 | 2.49130752 |
10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.26165862 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 2.22558304 |
12 | Parkinsons disease_Homo sapiens_hsa05012 | 2.20718644 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.20632106 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.19457307 |
15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.02305632 |
16 | RNA transport_Homo sapiens_hsa03013 | 1.87491230 |
17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.82730368 |
18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.81590271 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.80562983 |
20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.80263476 |
21 | Base excision repair_Homo sapiens_hsa03410 | 1.77532440 |
22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.66123133 |
23 | Alzheimers disease_Homo sapiens_hsa05010 | 1.60461400 |
24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51909339 |
25 | Cell cycle_Homo sapiens_hsa04110 | 1.43295187 |
26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.36897391 |
27 | Purine metabolism_Homo sapiens_hsa00230 | 1.34958214 |
28 | Phototransduction_Homo sapiens_hsa04744 | 1.15444251 |
29 | Allograft rejection_Homo sapiens_hsa05330 | 1.14696739 |
30 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.14427127 |
31 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.11934642 |
32 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.08562276 |
33 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.03080003 |
34 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.02392763 |
35 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.00777195 |
36 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.97524298 |
37 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.96906048 |
38 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.96436062 |
39 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.94852093 |
40 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.91535980 |
41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.90670995 |
42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.89360222 |
43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86523406 |
44 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85505313 |
45 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.84907474 |
46 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.84861046 |
47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.83580458 |
48 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.81880754 |
49 | Asthma_Homo sapiens_hsa05310 | 0.77521402 |
50 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.74394781 |
51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.70783732 |
52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.69933953 |
53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68430187 |
54 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.67815555 |
55 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.67758915 |
56 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.66022432 |
57 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.65835179 |
58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65834022 |
59 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64752759 |
60 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.64343858 |
61 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.63694867 |
62 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.62857741 |
63 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.61267189 |
64 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.59522594 |
65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57443821 |
66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54768468 |
67 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.54552120 |
68 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.54175341 |
69 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.52946249 |
70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.52773532 |
71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.51946249 |
72 | Malaria_Homo sapiens_hsa05144 | 0.51447064 |
73 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.50786412 |
74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47883365 |
75 | Measles_Homo sapiens_hsa05162 | 0.46921043 |
76 | Legionellosis_Homo sapiens_hsa05134 | 0.44859049 |
77 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.43016827 |
78 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41171175 |
79 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.39926090 |
80 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38963020 |
81 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38151792 |
82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.37787285 |
83 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.37622042 |
84 | Circadian rhythm_Homo sapiens_hsa04710 | 0.37554713 |
85 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.37536375 |
86 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37335867 |
87 | Shigellosis_Homo sapiens_hsa05131 | 0.36749301 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35018750 |
89 | Phagosome_Homo sapiens_hsa04145 | 0.34972934 |
90 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.34783291 |
91 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.34480918 |
92 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.34214742 |
93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34010905 |
94 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.33706476 |
95 | Alcoholism_Homo sapiens_hsa05034 | 0.33481134 |
96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33458273 |
97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32083533 |
98 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31942761 |
99 | Sulfur relay system_Homo sapiens_hsa04122 | 0.31211801 |
100 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.30561942 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.30194008 |
102 | Pertussis_Homo sapiens_hsa05133 | 0.29944057 |
103 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.28692347 |
104 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.27470951 |
105 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.25629879 |
106 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.24710814 |
107 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.24452050 |
108 | HTLV-I infection_Homo sapiens_hsa05166 | 0.21751717 |
109 | Peroxisome_Homo sapiens_hsa04146 | 0.21594821 |
110 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.21137863 |
111 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.20838036 |
112 | Hepatitis B_Homo sapiens_hsa05161 | 0.20741877 |
113 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.20222610 |
114 | Influenza A_Homo sapiens_hsa05164 | 0.20019305 |
115 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.19782883 |
116 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.19755338 |
117 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.18890782 |
118 | Leishmaniasis_Homo sapiens_hsa05140 | 0.17868030 |
119 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.16909687 |
120 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.15907854 |
121 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.13238519 |
122 | Carbon metabolism_Homo sapiens_hsa01200 | 0.12961898 |
123 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.12150505 |
124 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.10631412 |
125 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.09755588 |
126 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.08887057 |
127 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.06421669 |
128 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.03233482 |
129 | Melanoma_Homo sapiens_hsa05218 | 0.02886822 |
130 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.02822873 |
131 | Retinol metabolism_Homo sapiens_hsa00830 | 0.02553547 |