CCDC59

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)5.01890080
2proteasome assembly (GO:0043248)4.51737981
3termination of RNA polymerase III transcription (GO:0006386)4.37539246
4transcription elongation from RNA polymerase III promoter (GO:0006385)4.37539246
5ribosomal small subunit assembly (GO:0000028)4.31688164
6viral transcription (GO:0019083)4.20163710
7translational termination (GO:0006415)4.13782176
8maturation of SSU-rRNA (GO:0030490)4.10544178
9cotranslational protein targeting to membrane (GO:0006613)4.07715577
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.06206817
11RNA capping (GO:0036260)4.05481047
127-methylguanosine RNA capping (GO:0009452)4.05481047
13rRNA modification (GO:0000154)4.04768648
147-methylguanosine mRNA capping (GO:0006370)4.03550684
15protein targeting to ER (GO:0045047)4.00590048
16ribosomal large subunit biogenesis (GO:0042273)3.96050705
17transcription elongation from RNA polymerase I promoter (GO:0006362)3.94717344
18protein neddylation (GO:0045116)3.91006341
19histone exchange (GO:0043486)3.84593808
20DNA deamination (GO:0045006)3.82084754
21protein localization to endoplasmic reticulum (GO:0070972)3.81272962
22establishment of protein localization to endoplasmic reticulum (GO:0072599)3.80552313
23termination of RNA polymerase I transcription (GO:0006363)3.78120708
24ribosome assembly (GO:0042255)3.68204171
25centriole replication (GO:0007099)3.63409973
26transcription from RNA polymerase I promoter (GO:0006360)3.60918811
27respiratory electron transport chain (GO:0022904)3.57017310
28rRNA methylation (GO:0031167)3.55824945
29DNA replication-independent nucleosome assembly (GO:0006336)3.54287441
30DNA replication-independent nucleosome organization (GO:0034724)3.54287441
31ribonucleoprotein complex biogenesis (GO:0022613)3.52330035
32GTP biosynthetic process (GO:0006183)3.50053576
33rRNA processing (GO:0006364)3.49838886
34electron transport chain (GO:0022900)3.48743809
35translation (GO:0006412)3.43608070
36translational initiation (GO:0006413)3.43564960
37negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.42182437
38establishment of integrated proviral latency (GO:0075713)3.42109730
39mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.39914513
40DNA strand elongation involved in DNA replication (GO:0006271)3.39410291
41nuclear-transcribed mRNA catabolic process (GO:0000956)3.38257761
42rRNA metabolic process (GO:0016072)3.37477891
43viral life cycle (GO:0019058)3.36065916
44nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.33604964
45L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.33321299
46chaperone-mediated protein transport (GO:0072321)3.33199416
47transcription initiation from RNA polymerase I promoter (GO:0006361)3.32984907
48translational elongation (GO:0006414)3.32289604
49exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.31925457
50mitochondrial respiratory chain complex assembly (GO:0033108)3.29075819
51cellular protein complex disassembly (GO:0043624)3.28167346
52protein localization to kinetochore (GO:0034501)3.27971755
53positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.27058132
54histone mRNA metabolic process (GO:0008334)3.25374113
55DNA strand elongation (GO:0022616)3.25352086
56regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.24739536
57regulation of mitotic spindle checkpoint (GO:1903504)3.24739536
58mRNA catabolic process (GO:0006402)3.23901766
59establishment of viral latency (GO:0019043)3.23278652
60transcription-coupled nucleotide-excision repair (GO:0006283)3.22647497
61macromolecular complex disassembly (GO:0032984)3.21863553
62energy coupled proton transport, down electrochemical gradient (GO:0015985)3.20195077
63ATP synthesis coupled proton transport (GO:0015986)3.20195077
64telomere maintenance via recombination (GO:0000722)3.17757267
65maturation of 5.8S rRNA (GO:0000460)3.17029094
66protein targeting to mitochondrion (GO:0006626)3.16335744
67regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.15304170
68negative regulation of DNA-dependent DNA replication (GO:2000104)3.15261554
69mitotic G2/M transition checkpoint (GO:0044818)3.15066218
70cellular component biogenesis (GO:0044085)3.14584771
71DNA damage response, detection of DNA damage (GO:0042769)3.12669654
72negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.11984071
73negative regulation of ligase activity (GO:0051352)3.11984071
74DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.11648710
75nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.11069488
76protein localization to mitochondrion (GO:0070585)3.09487413
77positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)3.07944673
78anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.07452361
79nucleotide-excision repair, DNA gap filling (GO:0006297)3.06957981
80UTP biosynthetic process (GO:0006228)3.06865969
81RNA catabolic process (GO:0006401)3.05622113
82respiratory chain complex IV assembly (GO:0008535)3.05518552
83signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.04898223
84signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.04898223
85signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.04898223
86transcription elongation from RNA polymerase II promoter (GO:0006368)3.04525808
87intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.04408030
88signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.04408030
89metaphase plate congression (GO:0051310)3.03322403
90establishment of protein localization to mitochondrion (GO:0072655)3.01917553
91replication fork processing (GO:0031297)3.01793049
92regulation of mitochondrial translation (GO:0070129)3.00686784
93mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.99988385
94pseudouridine synthesis (GO:0001522)2.99573955
95mitotic recombination (GO:0006312)2.99203845
96DNA-templated transcription, elongation (GO:0006354)2.98159514
97antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.97617533
98mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.97561408
99mitochondrial respiratory chain complex I assembly (GO:0032981)2.97561408
100NADH dehydrogenase complex assembly (GO:0010257)2.97561408
101regulation of double-strand break repair via homologous recombination (GO:0010569)2.97428408
102pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.95998754
103signal transduction involved in DNA integrity checkpoint (GO:0072401)2.95945833
104signal transduction involved in DNA damage checkpoint (GO:0072422)2.95945833
105spliceosomal snRNP assembly (GO:0000387)2.95569762
106positive regulation of viral transcription (GO:0050434)2.95044933
107signal transduction involved in cell cycle checkpoint (GO:0072395)2.93341852
108spliceosomal complex assembly (GO:0000245)2.93335585
109protein localization to chromosome, centromeric region (GO:0071459)2.92667935
110guanosine-containing compound biosynthetic process (GO:1901070)2.92297618
111CENP-A containing nucleosome assembly (GO:0034080)2.92169566
112regulation of cellular amino acid metabolic process (GO:0006521)2.91892234
113inner mitochondrial membrane organization (GO:0007007)2.91000489
114protein targeting to membrane (GO:0006612)2.90129564
115base-excision repair, AP site formation (GO:0006285)2.89979356
116organelle disassembly (GO:1903008)2.89031153
117cullin deneddylation (GO:0010388)2.88707473
118kinetochore assembly (GO:0051382)2.88447576
119kinetochore organization (GO:0051383)2.87239484
120peptidyl-histidine modification (GO:0018202)2.86560300
121mitotic metaphase plate congression (GO:0007080)2.86211086
122antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.79260181
123positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.78408024
124protein complex biogenesis (GO:0070271)2.77444747
125mannosylation (GO:0097502)2.75897951
126formation of translation preinitiation complex (GO:0001731)2.72929625
127positive regulation of ligase activity (GO:0051351)2.72837429
128ribosome biogenesis (GO:0042254)2.72823636
129telomere maintenance via semi-conservative replication (GO:0032201)2.72612139
130protein complex disassembly (GO:0043241)2.72008841
131tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.71888200
132RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.71888200
133chromatin remodeling at centromere (GO:0031055)2.71851156
134establishment of protein localization to mitochondrial membrane (GO:0090151)2.71760918
135DNA-templated transcription, termination (GO:0006353)2.70064538
136DNA replication initiation (GO:0006270)2.67727753
137DNA replication checkpoint (GO:0000076)2.66475172
138ncRNA processing (GO:0034470)2.66397234

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.63853665
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.49919957
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.37242635
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.36852109
5E2F7_22180533_ChIP-Seq_HELA_Human4.03240751
6* EST1_17652178_ChIP-ChIP_JURKAT_Human3.97702056
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.54941096
8* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.50413346
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.46937711
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.35863445
11* ETS1_20019798_ChIP-Seq_JURKAT_Human3.32183613
12CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.18929773
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.09537946
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.08236483
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.78882388
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.73262733
17VDR_23849224_ChIP-Seq_CD4+_Human2.70883755
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.67964548
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.59400946
20MYC_19079543_ChIP-ChIP_MESCs_Mouse2.55246967
21ELK1_19687146_ChIP-ChIP_HELA_Human2.55128833
22* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.42919119
23* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.40855177
24DCP1A_22483619_ChIP-Seq_HELA_Human2.23190708
25FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.22548808
26* FOXP3_21729870_ChIP-Seq_TREG_Human2.15396804
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.11968762
28EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.11135267
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.02172043
30XRN2_22483619_ChIP-Seq_HELA_Human2.01604315
31E2F1_18555785_ChIP-Seq_MESCs_Mouse1.98021641
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.96767768
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94694245
34* TTF2_22483619_ChIP-Seq_HELA_Human1.90153179
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.89841880
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.83463493
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79971370
38ELK1_22589737_ChIP-Seq_MCF10A_Human1.78212149
39HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77028825
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.76763769
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.73349117
42* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.68569465
43GABP_19822575_ChIP-Seq_HepG2_Human1.66922951
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.61802685
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.59117626
46* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56268804
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.55451853
48* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.54935695
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.42803333
50MYC_18940864_ChIP-ChIP_HL60_Human1.37536717
51ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.36438472
52SALL1_21062744_ChIP-ChIP_HESCs_Human1.36367486
53* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31742821
54SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.31003368
55* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.30037175
56FUS_26573619_Chip-Seq_HEK293_Human1.28110229
57ERG_20887958_ChIP-Seq_HPC-7_Mouse1.27949866
58POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27033121
59FOXM1_23109430_ChIP-Seq_U2OS_Human1.22212583
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21260380
61ZNF274_21170338_ChIP-Seq_K562_Hela1.20639973
62VDR_22108803_ChIP-Seq_LS180_Human1.20517591
63NANOG_18555785_ChIP-Seq_MESCs_Mouse1.19913402
64IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.19799076
65POU5F1_16153702_ChIP-ChIP_HESCs_Human1.17696372
66* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15542767
67IRF8_21731497_ChIP-ChIP_J774_Mouse1.15426322
68POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14851908
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14153494
70CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.13071954
71IRF1_19129219_ChIP-ChIP_H3396_Human1.10349415
72EWS_26573619_Chip-Seq_HEK293_Human1.09050225
73CIITA_25753668_ChIP-Seq_RAJI_Human1.08134313
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.07676476
75SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05378293
76BP1_19119308_ChIP-ChIP_Hs578T_Human1.04645887
77HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01322153
78AR_21909140_ChIP-Seq_LNCAP_Human1.00822899
79E2F1_21310950_ChIP-Seq_MCF-7_Human1.00673481
80SOX17_20123909_ChIP-Seq_XEN_Mouse0.99830931
81SPI1_23547873_ChIP-Seq_NB4_Human0.99684728
82PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98983965
83FLI1_27457419_Chip-Seq_LIVER_Mouse0.98453555
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98444802
85TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94423299
86RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94276182
87* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92954350
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.91337061
89TFEB_21752829_ChIP-Seq_HELA_Human0.90999296
90* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.89192488
91STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87759959
92CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87732253
93KDM5A_27292631_Chip-Seq_BREAST_Human0.86869989
94SOX2_16153702_ChIP-ChIP_HESCs_Human0.86549607
95NANOG_16153702_ChIP-ChIP_HESCs_Human0.83042562
96SOX2_18555785_ChIP-Seq_MESCs_Mouse0.82721915
97TAF15_26573619_Chip-Seq_HEK293_Human0.82709214
98CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.82576435
99IGF1R_20145208_ChIP-Seq_DFB_Human0.82537305
100POU3F2_20337985_ChIP-ChIP_501MEL_Human0.82500925
101ZFX_18555785_ChIP-Seq_MESCs_Mouse0.81230395
102BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.80886922
103ELF5_23300383_ChIP-Seq_T47D_Human0.80861033
104EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.79808402
105KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.78099775
106KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.78099775
107KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.78099775
108NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.77918588
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.77884176
110ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.77575495
111ZFP57_27257070_Chip-Seq_ESCs_Mouse0.77101507
112CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.76489230
113DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75772528
114* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.74322100
115TP53_22573176_ChIP-Seq_HFKS_Human0.73191419
116* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71438691
117GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.70011145
118* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.68466598

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.90993640
2MP0008057_abnormal_DNA_replication3.53381987
3MP0003136_yellow_coat_color3.26527314
4MP0004957_abnormal_blastocyst_morpholog3.07626213
5MP0009379_abnormal_foot_pigmentation2.99155053
6MP0008058_abnormal_DNA_repair2.69469838
7MP0008932_abnormal_embryonic_tissue2.50056490
8MP0010094_abnormal_chromosome_stability2.30804016
9MP0001188_hyperpigmentation2.28474129
10MP0003111_abnormal_nucleus_morphology2.28183616
11MP0001529_abnormal_vocalization2.23245674
12MP0003077_abnormal_cell_cycle2.22541427
13MP0002163_abnormal_gland_morphology2.14487249
14MP0003806_abnormal_nucleotide_metabolis2.11578186
15MP0002277_abnormal_respiratory_mucosa2.10926355
16MP0006292_abnormal_olfactory_placode2.08195050
17MP0005379_endocrine/exocrine_gland_phen2.01993742
18MP0008007_abnormal_cellular_replicative1.91820783
19MP0003941_abnormal_skin_development1.88099454
20MP0008995_early_reproductive_senescence1.87152448
21MP0003718_maternal_effect1.86451931
22MP0003890_abnormal_embryonic-extraembry1.83508701
23MP0000372_irregular_coat_pigmentation1.75949024
24MP0002210_abnormal_sex_determination1.74295906
25MP0006036_abnormal_mitochondrial_physio1.64301614
26MP0005671_abnormal_response_to1.63727917
27MP0001929_abnormal_gametogenesis1.63556894
28MP0005409_darkened_coat_color1.61258134
29MP0002132_abnormal_respiratory_system1.60891453
30MP0006072_abnormal_retinal_apoptosis1.58605858
31MP0009697_abnormal_copulation1.57604371
32MP0004381_abnormal_hair_follicle1.53344353
33MP0001485_abnormal_pinna_reflex1.52250581
34MP0001905_abnormal_dopamine_level1.48670070
35MP0002638_abnormal_pupillary_reflex1.46473555
36MP0006035_abnormal_mitochondrial_morpho1.44341274
37MP0005171_absent_coat_pigmentation1.43350480
38MP0002938_white_spotting1.43019308
39MP0002102_abnormal_ear_morphology1.39688666
40MP0001145_abnormal_male_reproductive1.38827725
41MP0002148_abnormal_hypersensitivity_rea1.37398911
42MP0000015_abnormal_ear_pigmentation1.37260725
43MP0001764_abnormal_homeostasis1.35510445
44MP0000631_abnormal_neuroendocrine_gland1.35360439
45MP0000653_abnormal_sex_gland1.33049758
46MP0009333_abnormal_splenocyte_physiolog1.32386770
47MP0002234_abnormal_pharynx_morphology1.32024465
48MP0003121_genomic_imprinting1.31819730
49MP0003786_premature_aging1.31642723
50MP0003950_abnormal_plasma_membrane1.27708902
51MP0008260_abnormal_autophagy1.26518811
52MP0003567_abnormal_fetal_cardiomyocyte1.26036354
53MP0001835_abnormal_antigen_presentation1.23749111
54MP0004147_increased_porphyrin_level1.21443990
55MP0003315_abnormal_perineum_morphology1.21404929
56MP0009785_altered_susceptibility_to1.20754363
57MP0005410_abnormal_fertilization1.18729502
58MP0001697_abnormal_embryo_size1.18649047
59MP0003880_abnormal_central_pattern1.16273469
60MP0001919_abnormal_reproductive_system1.15733494
61MP0003186_abnormal_redox_activity1.15500342
62MP0003763_abnormal_thymus_physiology1.15489638
63MP0003195_calcinosis1.10565936
64MP0005646_abnormal_pituitary_gland1.07223911
65MP0004742_abnormal_vestibular_system1.06704944
66MP0003698_abnormal_male_reproductive1.06202587
67MP0005000_abnormal_immune_tolerance1.05560906
68MP0005075_abnormal_melanosome_morpholog1.04562898
69MP0000678_abnormal_parathyroid_gland1.04309336
70MP0000350_abnormal_cell_proliferation1.03758889
71MP0005394_taste/olfaction_phenotype1.02479389
72MP0005499_abnormal_olfactory_system1.02479389
73MP0002160_abnormal_reproductive_system1.00900538
74MP0003787_abnormal_imprinting1.00677239
75MP0002751_abnormal_autonomic_nervous1.00082854
76MP0003938_abnormal_ear_development0.99800200
77MP0000566_synostosis0.99743691
78MP0001542_abnormal_bone_strength0.99354869
79MP0005408_hypopigmentation0.98656053
80MP0000613_abnormal_salivary_gland0.98585730
81MP0003724_increased_susceptibility_to0.98030032
82MP0004142_abnormal_muscle_tone0.97987869
83MP0002723_abnormal_immune_serum0.96755476
84MP0002095_abnormal_skin_pigmentation0.96105040
85MP0002019_abnormal_tumor_incidence0.95903000
86MP0001672_abnormal_embryogenesis/_devel0.95745517
87MP0005380_embryogenesis_phenotype0.95745517
88MP0005266_abnormal_metabolism0.94555791
89MP0005395_other_phenotype0.94276755
90MP0002452_abnormal_antigen_presenting0.93567860
91MP0000049_abnormal_middle_ear0.93045089
92MP0005084_abnormal_gallbladder_morpholo0.92689674
93MP0000703_abnormal_thymus_morphology0.92347867
94MP0004133_heterotaxia0.92019905
95MP0002420_abnormal_adaptive_immunity0.91429174
96MP0001819_abnormal_immune_cell0.91066652
97MP0001800_abnormal_humoral_immune0.90682971
98MP0005174_abnormal_tail_pigmentation0.89885193
99MP0005387_immune_system_phenotype0.89679948
100MP0001790_abnormal_immune_system0.89679948
101MP0000026_abnormal_inner_ear0.88476049
102MP0001853_heart_inflammation0.87651196
103MP0008877_abnormal_DNA_methylation0.87511922
104MP0008789_abnormal_olfactory_epithelium0.87367236
105MP0001119_abnormal_female_reproductive0.87337205
106MP0002396_abnormal_hematopoietic_system0.86757018
107MP0010307_abnormal_tumor_latency0.86695322
108MP0000313_abnormal_cell_death0.85557079
109MP0005389_reproductive_system_phenotype0.85456118
110MP0002084_abnormal_developmental_patter0.84482327
111MP0000858_altered_metastatic_potential0.83409708
112MP0005253_abnormal_eye_physiology0.83366058
113MP0001986_abnormal_taste_sensitivity0.83322038
114MP0003656_abnormal_erythrocyte_physiolo0.82402662
115MP0002085_abnormal_embryonic_tissue0.81777512
116MP0002080_prenatal_lethality0.81755884
117MP0002398_abnormal_bone_marrow0.81429182
118MP0001293_anophthalmia0.81251744
119MP0006082_CNS_inflammation0.80999745
120MP0003123_paternal_imprinting0.80962573
121MP0002161_abnormal_fertility/fecundity0.80869244
122MP0005551_abnormal_eye_electrophysiolog0.80250285
123MP0005025_abnormal_response_to0.80069104
124MP0003699_abnormal_female_reproductive0.79961887
125MP0000358_abnormal_cell_content/0.79573842
126MP0003984_embryonic_growth_retardation0.77492152
127MP0003937_abnormal_limbs/digits/tail_de0.77161381
128MP0001286_abnormal_eye_development0.75754614
129MP0002088_abnormal_embryonic_growth/wei0.75366953
130MP0001730_embryonic_growth_arrest0.74171844
131MP0000716_abnormal_immune_system0.73952991
132MP0001963_abnormal_hearing_physiology0.73674630
133MP0000490_abnormal_crypts_of0.73359794
134MP0002177_abnormal_outer_ear0.71262587
135MP0002722_abnormal_immune_system0.70354623
136MP0002419_abnormal_innate_immunity0.70349464
137MP0004197_abnormal_fetal_growth/weight/0.69627074
138MP0000920_abnormal_myelination0.68743073
139MP0000689_abnormal_spleen_morphology0.68453524
140MP0010030_abnormal_orbit_morphology0.67879879
141MP0008961_abnormal_basal_metabolism0.67647922
142MP0003936_abnormal_reproductive_system0.66055457
143MP0002405_respiratory_system_inflammati0.65440435
144MP0002429_abnormal_blood_cell0.64842102
145MP0005391_vision/eye_phenotype0.61595058
146MP0000427_abnormal_hair_cycle0.59681291
147MP0003119_abnormal_digestive_system0.56784310
148MP0001324_abnormal_eye_pigmentation0.56085165

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.11191939
2Acute necrotizing encephalopathy (HP:0006965)3.96612526
3Mitochondrial inheritance (HP:0001427)3.54811333
4Abnormality of cells of the erythroid lineage (HP:0012130)3.31849420
5Increased hepatocellular lipid droplets (HP:0006565)3.31277351
6Abnormal mitochondria in muscle tissue (HP:0008316)3.28132135
7Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.23084889
8Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.22399885
9Reticulocytopenia (HP:0001896)3.21172272
10Progressive macrocephaly (HP:0004481)3.18075114
11Abnormal number of erythroid precursors (HP:0012131)3.15794795
123-Methylglutaconic aciduria (HP:0003535)3.03366212
13Cerebral edema (HP:0002181)3.00765230
14Parakeratosis (HP:0001036)2.99010390
15Increased CSF lactate (HP:0002490)2.96644353
16Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.95374451
17Hepatocellular necrosis (HP:0001404)2.91805777
18Renal Fanconi syndrome (HP:0001994)2.88177911
19Acute encephalopathy (HP:0006846)2.84172253
20Breast hypoplasia (HP:0003187)2.83179281
21Increased intramyocellular lipid droplets (HP:0012240)2.80807002
22Macrocytic anemia (HP:0001972)2.72690635
23Type I transferrin isoform profile (HP:0003642)2.72306454
24Cerebral hypomyelination (HP:0006808)2.70569978
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.60326403
26Exertional dyspnea (HP:0002875)2.55467165
27Volvulus (HP:0002580)2.53266523
28Methylmalonic acidemia (HP:0002912)2.49877071
29Lipid accumulation in hepatocytes (HP:0006561)2.49299574
30Methylmalonic aciduria (HP:0012120)2.47288241
31Oral leukoplakia (HP:0002745)2.46364464
32Medial flaring of the eyebrow (HP:0010747)2.43647364
33Chronic hepatic failure (HP:0100626)2.43570549
34Rough bone trabeculation (HP:0100670)2.42618309
35Lactic acidosis (HP:0003128)2.42361330
36Stenosis of the external auditory canal (HP:0000402)2.41410095
37Pallor (HP:0000980)2.38691853
38Supernumerary spleens (HP:0009799)2.38650057
39True hermaphroditism (HP:0010459)2.34298079
40Abnormality of the pons (HP:0007361)2.33762172
41Irregular epiphyses (HP:0010582)2.32550588
42Adrenal hypoplasia (HP:0000835)2.32085528
43Pancreatic fibrosis (HP:0100732)2.30740355
44Congenital, generalized hypertrichosis (HP:0004540)2.28141436
45Cleft eyelid (HP:0000625)2.26680237
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.25121649
47Premature ovarian failure (HP:0008209)2.24455406
48Pancreatic cysts (HP:0001737)2.23496812
49Increased muscle lipid content (HP:0009058)2.22768437
50Small epiphyses (HP:0010585)2.21014376
51Increased serum pyruvate (HP:0003542)2.20799054
52Abnormality of glycolysis (HP:0004366)2.20799054
53Aplasia/hypoplasia of the uterus (HP:0008684)2.20037889
54Abnormality of the preputium (HP:0100587)2.19939381
55Colon cancer (HP:0003003)2.18244871
56Increased serum lactate (HP:0002151)2.17969580
57Respiratory difficulties (HP:0002880)2.16311235
58Hepatic necrosis (HP:0002605)2.15546493
59Congenital primary aphakia (HP:0007707)2.15274272
60Abnormal trabecular bone morphology (HP:0100671)2.15201090
61Leukodystrophy (HP:0002415)2.14992275
62Optic disc pallor (HP:0000543)2.14407911
63Chromsome breakage (HP:0040012)2.14054164
64Hypoplasia of the pons (HP:0012110)2.11114577
65Myelodysplasia (HP:0002863)2.11011748
66Degeneration of anterior horn cells (HP:0002398)2.07804754
67Abnormality of the anterior horn cell (HP:0006802)2.07804754
68Exercise intolerance (HP:0003546)2.07701420
69Pancytopenia (HP:0001876)2.07407282
70Small intestinal stenosis (HP:0012848)2.05261910
71Duodenal stenosis (HP:0100867)2.05261910
72Absent septum pellucidum (HP:0001331)2.04727689
73Nephrogenic diabetes insipidus (HP:0009806)2.03514097
74Decreased activity of mitochondrial respiratory chain (HP:0008972)2.03023309
75Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.03023309
76Gait imbalance (HP:0002141)2.02002095
77Abnormality of methionine metabolism (HP:0010901)2.01600935
78Absent thumb (HP:0009777)2.01360812
79Abnormality of the septum pellucidum (HP:0007375)2.00626865
80Reduced antithrombin III activity (HP:0001976)2.00608041
81Patellar aplasia (HP:0006443)1.97794586
82Cupped ear (HP:0000378)1.97076983
83Abnormality of aspartate family amino acid metabolism (HP:0010899)1.95503829
84Oligodactyly (hands) (HP:0001180)1.94163079
85Multiple enchondromatosis (HP:0005701)1.93047372
86Triphalangeal thumb (HP:0001199)1.91286745
87Abnormality of the renal collecting system (HP:0004742)1.91115671
88Homocystinuria (HP:0002156)1.90044777
89Abnormality of homocysteine metabolism (HP:0010919)1.90044777
90Abnormality of renal resorption (HP:0011038)1.89392648
91Meckel diverticulum (HP:0002245)1.87719338
92Aplasia/Hypoplasia of the patella (HP:0006498)1.87089052
93Nasolacrimal duct obstruction (HP:0000579)1.86678663
94Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.86460327
95Abnormal protein N-linked glycosylation (HP:0012347)1.86460327
96Abnormal protein glycosylation (HP:0012346)1.86460327
97Abnormal glycosylation (HP:0012345)1.86460327
98Abnormality of midbrain morphology (HP:0002418)1.85818980
99Molar tooth sign on MRI (HP:0002419)1.85818980
100Aplasia/Hypoplasia of the sacrum (HP:0008517)1.85782934
101Congenital ichthyosiform erythroderma (HP:0007431)1.85537761
102Megaloblastic anemia (HP:0001889)1.85272366
103Sloping forehead (HP:0000340)1.84991150
104Abnormal hemoglobin (HP:0011902)1.83859508
105Hypoplastic pelvis (HP:0008839)1.83585849
106Respiratory failure (HP:0002878)1.82815787
107Aplastic anemia (HP:0001915)1.82492468
108Sensory axonal neuropathy (HP:0003390)1.82322757
109Intestinal atresia (HP:0011100)1.81819112
110Trismus (HP:0000211)1.80020580
111Secondary amenorrhea (HP:0000869)1.79704832
112Abnormality of the ileum (HP:0001549)1.79638100
113Abnormal spermatogenesis (HP:0008669)1.78347612
114Anencephaly (HP:0002323)1.78340130
115Abnormal lung lobation (HP:0002101)1.78274451
116Abnormality of chromosome stability (HP:0003220)1.77795596
117Delayed epiphyseal ossification (HP:0002663)1.77794993
118Prolonged neonatal jaundice (HP:0006579)1.77675636
119Vaginal atresia (HP:0000148)1.77342049
120Abnormality of the duodenum (HP:0002246)1.76868992
121Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.76614372
122Absent epiphyses (HP:0010577)1.76614372
123Gonadotropin excess (HP:0000837)1.74697062
124Flat capital femoral epiphysis (HP:0003370)1.72940035
125Hypoplasia of the capital femoral epiphysis (HP:0003090)1.71930086
126Abnormal hair whorl (HP:0010721)1.71414543
127Duplicated collecting system (HP:0000081)1.70922137
128Conical tooth (HP:0000698)1.69538189
129Abnormality of the labia minora (HP:0012880)1.69091513
130Azoospermia (HP:0000027)1.68760162
131Microvesicular hepatic steatosis (HP:0001414)1.68327568
132Lethargy (HP:0001254)1.68320133
133Septo-optic dysplasia (HP:0100842)1.68101583
134Genital tract atresia (HP:0001827)1.67887818
135Horseshoe kidney (HP:0000085)1.67732226
136Aplasia involving forearm bones (HP:0009822)1.66863001
137Absent forearm bone (HP:0003953)1.66863001
138Absent radius (HP:0003974)1.66481448
139Nephroblastoma (Wilms tumor) (HP:0002667)1.66359743
140Sclerocornea (HP:0000647)1.66326003
141Asplenia (HP:0001746)1.65968900
142Glycosuria (HP:0003076)1.65611087
143Abnormality of urine glucose concentration (HP:0011016)1.65611087

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PBK3.78192852
2BUB12.98225233
3EIF2AK32.94045042
4STK162.92546194
5VRK22.74079238
6EIF2AK12.71154488
7MKNK12.52727476
8SRPK12.46558520
9VRK12.33355716
10PIM22.22708695
11CASK2.20347207
12MKNK22.19814646
13TLK12.11714247
14NME12.08424784
15WEE12.05418373
16NME22.02817644
17MST41.88902420
18IRAK41.84223073
19NEK11.81956500
20INSRR1.81089992
21TESK21.80307045
22PLK41.74046141
23TXK1.69534252
24IRAK31.64273762
25TSSK61.62757079
26EIF2AK21.56363558
27PNCK1.53761824
28WNK31.50698614
29PLK31.44010872
30NEK21.35697089
31STK391.31321149
32BRSK21.30941678
33TNIK1.27611312
34BRAF1.24657780
35BMPR1B1.23466548
36BCR1.22513083
37TAOK31.17914163
38RPS6KA51.12990568
39PLK11.11737027
40CDC71.08857632
41BMPR21.07786336
42TAF11.07237766
43DYRK21.07141597
44ADRBK21.05138428
45TRIM281.03351738
46GRK11.02195027
47AURKA1.00342953
48NEK60.97276376
49OXSR10.97084624
50RPS6KB20.95598181
51LATS10.92042838
52ZAK0.90452150
53MAPK150.89286295
54AURKB0.89176222
55CDK30.87638001
56PDK20.87105931
57YES10.86670821
58IKBKB0.86322299
59PLK20.83503764
60DYRK30.81041097
61RPS6KA40.79501877
62IRAK10.79238403
63CDK190.79053022
64STK30.78451910
65GRK70.78341122
66MAP2K20.76759821
67MAP3K140.75638471
68TEC0.75344097
69ARAF0.74572938
70CDK80.73391915
71PASK0.73301586
72MAPKAPK50.72502953
73LIMK10.71833281
74TTK0.71810405
75CSNK2A10.71200738
76MARK30.70933298
77MAP3K120.70792160
78NUAK10.66868968
79CDK70.64632026
80BRD40.64613896
81CSNK2A20.62087911
82CSNK1E0.61601170
83ATR0.61375739
84BRSK10.60739326
85KIT0.60235857
86IKBKE0.60190753
87ERBB30.58490218
88LYN0.57775872
89EPHA20.57443328
90CDK20.56829387
91CLK10.56067864
92MAP3K40.56045203
93STK240.55410349
94CDK90.55169773
95PKN10.53897698
96NLK0.50871484
97ACVR1B0.49472788
98CCNB10.49431267
99CHEK20.45910359
100CHEK10.45261675
101WNK40.45003791
102PAK10.43768777
103IRAK20.42718277
104NEK90.39748285
105ATM0.39455426
106LCK0.39381004
107STK40.38726128
108AKT30.37537160
109FGR0.37516381
110SIK30.37166059
111CAMK2B0.37051005
112PRKCI0.36947030
113ABL20.35771563
114PIM10.35747927
115STK38L0.35096816
116PIK3CA0.34945957
117BLK0.34374641
118MAP4K20.34214585
119CDK10.34133679
120CDK40.34096949
121CSNK1G10.33180627
122MAPK130.32581450
123MAP2K70.32237987
124FRK0.30918504
125ALK0.30743001
126PIK3CG0.30328983
127TGFBR10.28620349
128PRKACB0.27100116
129STK100.24871926
130BCKDK0.24764338
131CSNK1G20.24614827
132CHUK0.24034207
133PRKCG0.23910122
134CSNK1G30.23487187

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.26873492
2Proteasome_Homo sapiens_hsa030503.89182883
3RNA polymerase_Homo sapiens_hsa030203.87583645
4Protein export_Homo sapiens_hsa030603.32957066
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.76231847
6Oxidative phosphorylation_Homo sapiens_hsa001902.71900476
7Spliceosome_Homo sapiens_hsa030402.60667387
8DNA replication_Homo sapiens_hsa030302.54221325
9Mismatch repair_Homo sapiens_hsa034302.49130752
10Basal transcription factors_Homo sapiens_hsa030222.26165862
11Homologous recombination_Homo sapiens_hsa034402.22558304
12Parkinsons disease_Homo sapiens_hsa050122.20718644
13Nucleotide excision repair_Homo sapiens_hsa034202.20632106
14Pyrimidine metabolism_Homo sapiens_hsa002402.19457307
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.02305632
16RNA transport_Homo sapiens_hsa030131.87491230
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.82730368
18Fanconi anemia pathway_Homo sapiens_hsa034601.81590271
19RNA degradation_Homo sapiens_hsa030181.80562983
20Huntingtons disease_Homo sapiens_hsa050161.80263476
21Base excision repair_Homo sapiens_hsa034101.77532440
22Non-homologous end-joining_Homo sapiens_hsa034501.66123133
23Alzheimers disease_Homo sapiens_hsa050101.60461400
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51909339
25Cell cycle_Homo sapiens_hsa041101.43295187
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36897391
27Purine metabolism_Homo sapiens_hsa002301.34958214
28Phototransduction_Homo sapiens_hsa047441.15444251
29Allograft rejection_Homo sapiens_hsa053301.14696739
30Vitamin B6 metabolism_Homo sapiens_hsa007501.14427127
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.11934642
32Epstein-Barr virus infection_Homo sapiens_hsa051691.08562276
33Cysteine and methionine metabolism_Homo sapiens_hsa002701.03080003
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.02392763
35SNARE interactions in vesicular transport_Homo sapiens_hsa041301.00777195
36Propanoate metabolism_Homo sapiens_hsa006400.97524298
37p53 signaling pathway_Homo sapiens_hsa041150.96906048
38Autoimmune thyroid disease_Homo sapiens_hsa053200.96436062
39mRNA surveillance pathway_Homo sapiens_hsa030150.94852093
40Steroid biosynthesis_Homo sapiens_hsa001000.91535980
41Graft-versus-host disease_Homo sapiens_hsa053320.90670995
42Rheumatoid arthritis_Homo sapiens_hsa053230.89360222
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.86523406
44Arachidonic acid metabolism_Homo sapiens_hsa005900.85505313
45Selenocompound metabolism_Homo sapiens_hsa004500.84907474
46Primary immunodeficiency_Homo sapiens_hsa053400.84861046
47Ether lipid metabolism_Homo sapiens_hsa005650.83580458
48Sphingolipid metabolism_Homo sapiens_hsa006000.81880754
49Asthma_Homo sapiens_hsa053100.77521402
50NOD-like receptor signaling pathway_Homo sapiens_hsa046210.74394781
51Sulfur metabolism_Homo sapiens_hsa009200.70783732
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69933953
53Collecting duct acid secretion_Homo sapiens_hsa049660.68430187
54NF-kappa B signaling pathway_Homo sapiens_hsa040640.67815555
55Herpes simplex infection_Homo sapiens_hsa051680.67758915
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.66022432
57Hematopoietic cell lineage_Homo sapiens_hsa046400.65835179
58Regulation of autophagy_Homo sapiens_hsa041400.65834022
59Pyruvate metabolism_Homo sapiens_hsa006200.64752759
60Type I diabetes mellitus_Homo sapiens_hsa049400.64343858
61Folate biosynthesis_Homo sapiens_hsa007900.63694867
62Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.62857741
63Linoleic acid metabolism_Homo sapiens_hsa005910.61267189
64One carbon pool by folate_Homo sapiens_hsa006700.59522594
65Systemic lupus erythematosus_Homo sapiens_hsa053220.57443821
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54768468
67Intestinal immune network for IgA production_Homo sapiens_hsa046720.54552120
68Antigen processing and presentation_Homo sapiens_hsa046120.54175341
69Vibrio cholerae infection_Homo sapiens_hsa051100.52946249
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52773532
71Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51946249
72Malaria_Homo sapiens_hsa051440.51447064
73Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50786412
74Glutathione metabolism_Homo sapiens_hsa004800.47883365
75Measles_Homo sapiens_hsa051620.46921043
76Legionellosis_Homo sapiens_hsa051340.44859049
77Caffeine metabolism_Homo sapiens_hsa002320.43016827
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41171175
79Fatty acid elongation_Homo sapiens_hsa000620.39926090
80Viral carcinogenesis_Homo sapiens_hsa052030.38963020
81Metabolic pathways_Homo sapiens_hsa011000.38151792
82Vitamin digestion and absorption_Homo sapiens_hsa049770.37787285
83Cardiac muscle contraction_Homo sapiens_hsa042600.37622042
84Circadian rhythm_Homo sapiens_hsa047100.37554713
85Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.37536375
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37335867
87Shigellosis_Homo sapiens_hsa051310.36749301
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.35018750
89Phagosome_Homo sapiens_hsa041450.34972934
90Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34783291
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34480918
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.34214742
93Olfactory transduction_Homo sapiens_hsa047400.34010905
94Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.33706476
95Alcoholism_Homo sapiens_hsa050340.33481134
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33458273
97Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32083533
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31942761
99Sulfur relay system_Homo sapiens_hsa041220.31211801
100Butanoate metabolism_Homo sapiens_hsa006500.30561942
101Apoptosis_Homo sapiens_hsa042100.30194008
102Pertussis_Homo sapiens_hsa051330.29944057
103Maturity onset diabetes of the young_Homo sapiens_hsa049500.28692347
104Serotonergic synapse_Homo sapiens_hsa047260.27470951
105Transcriptional misregulation in cancer_Homo sapiens_hsa052020.25629879
106Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.24710814
107Nitrogen metabolism_Homo sapiens_hsa009100.24452050
108HTLV-I infection_Homo sapiens_hsa051660.21751717
109Peroxisome_Homo sapiens_hsa041460.21594821
110N-Glycan biosynthesis_Homo sapiens_hsa005100.21137863
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20838036
112Hepatitis B_Homo sapiens_hsa051610.20741877
113TGF-beta signaling pathway_Homo sapiens_hsa043500.20222610
114Influenza A_Homo sapiens_hsa051640.20019305
115T cell receptor signaling pathway_Homo sapiens_hsa046600.19782883
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.19755338
117Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.18890782
118Leishmaniasis_Homo sapiens_hsa051400.17868030
119Oocyte meiosis_Homo sapiens_hsa041140.16909687
120Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.15907854
121Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13238519
122Carbon metabolism_Homo sapiens_hsa012000.12961898
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.12150505
124Hedgehog signaling pathway_Homo sapiens_hsa043400.10631412
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.09755588
126Tryptophan metabolism_Homo sapiens_hsa003800.08887057
127Basal cell carcinoma_Homo sapiens_hsa052170.06421669
128Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.03233482
129Melanoma_Homo sapiens_hsa052180.02886822
130Biosynthesis of amino acids_Homo sapiens_hsa012300.02822873
131Retinol metabolism_Homo sapiens_hsa008300.02553547

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