CCDC60

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1motile cilium assembly (GO:0044458)9.94529653
2epithelial cilium movement (GO:0003351)9.91738385
3binding of sperm to zona pellucida (GO:0007339)9.90297350
4cell-cell recognition (GO:0009988)9.65127109
5plasma membrane fusion (GO:0045026)9.63319259
6piRNA metabolic process (GO:0034587)9.61197781
7spermatid development (GO:0007286)9.18841345
8reproduction (GO:0000003)8.59309693
9cilium movement (GO:0003341)8.55494727
10regulation of cilium movement (GO:0003352)8.49305418
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.37129813
12male meiosis (GO:0007140)8.22569712
13synaptonemal complex organization (GO:0070193)7.57335045
14single fertilization (GO:0007338)7.27239688
15synaptonemal complex assembly (GO:0007130)7.25189485
16sperm capacitation (GO:0048240)6.98417728
17DNA methylation involved in gamete generation (GO:0043046)6.44454702
18fertilization (GO:0009566)6.22987193
19spermatogenesis (GO:0007283)6.19752307
20male gamete generation (GO:0048232)6.17615059
21negative regulation of inclusion body assembly (GO:0090084)6.10673193
22male meiosis I (GO:0007141)5.99774489
23microtubule depolymerization (GO:0007019)5.80628025
24vitamin transmembrane transport (GO:0035461)5.71279536
25gamete generation (GO:0007276)5.68669175
26organic cation transport (GO:0015695)5.60318327
27microtubule bundle formation (GO:0001578)5.57769744
28ventricular system development (GO:0021591)5.47101658
29germ cell development (GO:0007281)5.35491204
30cellular process involved in reproduction in multicellular organism (GO:0022412)5.30277857
31chromosome organization involved in meiosis (GO:0070192)5.30020385
32primary alcohol catabolic process (GO:0034310)5.27345671
33seminiferous tubule development (GO:0072520)5.03414130
34regulation of inclusion body assembly (GO:0090083)4.96375144
35meiotic nuclear division (GO:0007126)4.92645673
36retinal cone cell development (GO:0046549)4.91007037
37calcium ion-dependent exocytosis (GO:0017156)4.78151873
38meiosis I (GO:0007127)4.74957016
39meiotic cell cycle (GO:0051321)4.62661385
40regulation of microtubule-based movement (GO:0060632)4.62303804
41microtubule severing (GO:0051013)4.57558198
42cell recognition (GO:0008037)4.56536650
43left/right pattern formation (GO:0060972)4.55830696
44multicellular organismal reproductive process (GO:0048609)4.45059797
45protein localization to cilium (GO:0061512)4.43032459
46one-carbon compound transport (GO:0019755)4.30889677
47ethanol metabolic process (GO:0006067)4.17611659
48retinal rod cell development (GO:0046548)4.10529123
49pyrimidine-containing compound transmembrane transport (GO:0072531)4.09553567
50diterpenoid biosynthetic process (GO:0016102)4.09346835
51regulation of interleukin-5 production (GO:0032674)3.94077563
52cell projection assembly (GO:0030031)3.93747473
53intraciliary transport (GO:0042073)3.92851214
54monoubiquitinated protein deubiquitination (GO:0035520)3.88505233
55protein polyglutamylation (GO:0018095)3.77480011
56negative regulation of T cell differentiation in thymus (GO:0033085)3.75529845
57photoreceptor cell maintenance (GO:0045494)3.73088840
58DNA packaging (GO:0006323)3.72261995
59diol metabolic process (GO:0034311)3.70122400
60multicellular organismal development (GO:0007275)3.68115245
61genitalia morphogenesis (GO:0035112)3.66067888
62chromosome condensation (GO:0030261)3.65577881
63glomerular epithelial cell development (GO:0072310)3.65553396
64response to xenobiotic stimulus (GO:0009410)3.56535664
65axoneme assembly (GO:0035082)3.51166948
66glycerol ether metabolic process (GO:0006662)3.48816628
67synapsis (GO:0007129)3.47166636
68sphingoid metabolic process (GO:0046519)3.43627756
69cilium organization (GO:0044782)3.43159924
70meiotic cell cycle process (GO:1903046)3.38912206
71exogenous drug catabolic process (GO:0042738)3.37258593
72spermatid nucleus differentiation (GO:0007289)3.36381785
73regulation of spindle checkpoint (GO:0090231)3.35235586
74gene silencing by RNA (GO:0031047)3.34964913
75cilium assembly (GO:0042384)3.30426717
76retinoic acid metabolic process (GO:0042573)3.30221547
77centriole assembly (GO:0098534)3.27310278
78sphingosine metabolic process (GO:0006670)3.22452597
79ether metabolic process (GO:0018904)3.21899863
80determination of left/right symmetry (GO:0007368)3.18357425
81cytoplasmic microtubule organization (GO:0031122)3.17104019
82lung epithelium development (GO:0060428)3.15513682
83cilium morphogenesis (GO:0060271)3.07233573
84microtubule-based movement (GO:0007018)3.03439367
85cellular component assembly involved in morphogenesis (GO:0010927)3.03024977
86determination of bilateral symmetry (GO:0009855)3.02565480
87negative regulation of humoral immune response (GO:0002921)3.01781461
88smoothened signaling pathway (GO:0007224)3.01342078
89chaperone-mediated protein complex assembly (GO:0051131)3.00156235
90regulation of centriole replication (GO:0046599)2.98004170
91establishment of apical/basal cell polarity (GO:0035089)2.97950202
92lactate metabolic process (GO:0006089)2.97888178
93sequestering of actin monomers (GO:0042989)2.95628758
94ethanol oxidation (GO:0006069)2.95626358
95nonmotile primary cilium assembly (GO:0035058)2.95551690
96specification of symmetry (GO:0009799)2.95208141
97negative regulation of immunoglobulin mediated immune response (GO:0002890)2.94935995
98negative regulation of B cell mediated immunity (GO:0002713)2.94935995
99protein K11-linked deubiquitination (GO:0035871)2.93231056
100mitotic sister chromatid cohesion (GO:0007064)2.93060337
101regulation of meiosis I (GO:0060631)2.92851844
102establishment or maintenance of monopolar cell polarity (GO:0061339)2.91272580
103establishment of monopolar cell polarity (GO:0061162)2.91272580
104terpenoid biosynthetic process (GO:0016114)2.90687608
105polyol catabolic process (GO:0046174)2.89548722
106lateral ventricle development (GO:0021670)2.89039655
107protein refolding (GO:0042026)2.88093055
108nucleus organization (GO:0006997)2.86766549
109nucleoside diphosphate phosphorylation (GO:0006165)2.85744664
110O-glycan processing (GO:0016266)2.85535623
111negative regulation of organelle assembly (GO:1902116)2.85149723
112nuclear pore complex assembly (GO:0051292)2.82388243
113glutathione derivative biosynthetic process (GO:1901687)2.81940833
114glutathione derivative metabolic process (GO:1901685)2.81940833
115single strand break repair (GO:0000012)2.80835694
116centriole replication (GO:0007099)2.80817550
117photoreceptor cell development (GO:0042461)2.79655312
118microtubule polymerization or depolymerization (GO:0031109)2.78712818
119tolerance induction (GO:0002507)2.77312852
120response to pheromone (GO:0019236)2.77261069
121cornea development in camera-type eye (GO:0061303)2.76829027
122drug catabolic process (GO:0042737)2.74818354
123regulation of germinal center formation (GO:0002634)2.72179963
124carnitine transport (GO:0015879)2.72116533
125amino-acid betaine transport (GO:0015838)2.72116533
126phosphatidylethanolamine metabolic process (GO:0046337)2.70317953
127organelle assembly (GO:0070925)2.69003125
128phosphatidylethanolamine biosynthetic process (GO:0006646)2.68879367
129retinol metabolic process (GO:0042572)2.67384961
130carnitine transmembrane transport (GO:1902603)2.67232008
131CDP-diacylglycerol biosynthetic process (GO:0016024)2.66630840
132establishment of tissue polarity (GO:0007164)2.66312282
133establishment of planar polarity (GO:0001736)2.66312282
134negative regulation of skeletal muscle tissue development (GO:0048642)2.66152273
135eye photoreceptor cell development (GO:0042462)2.65018419
136regulation of interleukin-13 production (GO:0032656)2.63057346
137excretion (GO:0007588)2.61932852
138interferon-gamma secretion (GO:0072643)2.61623865
139alditol metabolic process (GO:0019400)2.60814639
140regulation of collateral sprouting (GO:0048670)2.59478470
141microtubule-based process (GO:0007017)2.57656763
142RNA destabilization (GO:0050779)2.56941141
143protein-chromophore linkage (GO:0018298)2.56333097
144cellular ketone body metabolic process (GO:0046950)2.55475905
145primary alcohol metabolic process (GO:0034308)2.54960476
146left/right axis specification (GO:0070986)2.53286223
147DNA methylation (GO:0006306)2.52747013
148DNA alkylation (GO:0006305)2.52747013
149neurotransmitter metabolic process (GO:0042133)2.51311421
150GTP biosynthetic process (GO:0006183)2.50572255
151regulation of protein polyubiquitination (GO:1902914)2.50427326
152regulation of autophagic vacuole assembly (GO:2000785)2.48998162
153neurotransmitter biosynthetic process (GO:0042136)2.46422257
154reactive oxygen species biosynthetic process (GO:1903409)2.45434685
155detection of light stimulus involved in sensory perception (GO:0050962)2.43653413
156detection of light stimulus involved in visual perception (GO:0050908)2.43653413
157spinal cord motor neuron differentiation (GO:0021522)2.41333184
158cilium or flagellum-dependent cell motility (GO:0001539)13.2269891
159fusion of sperm to egg plasma membrane (GO:0007342)12.6307274
160sperm motility (GO:0030317)12.5069974
161acrosome reaction (GO:0007340)11.1533153
162sperm-egg recognition (GO:0035036)10.8295602
163axonemal dynein complex assembly (GO:0070286)10.7586014
164acrosome assembly (GO:0001675)10.5767764
165multicellular organism reproduction (GO:0032504)10.5288508
166cell wall macromolecule catabolic process (GO:0016998)10.0923321
167cell wall macromolecule metabolic process (GO:0044036)10.0923321

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.90726197
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.64822762
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.30432290
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.57917953
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.56303430
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42941885
7PCGF2_27294783_Chip-Seq_ESCs_Mouse2.35593879
8IGF1R_20145208_ChIP-Seq_DFB_Human2.34715455
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.34618761
10VDR_22108803_ChIP-Seq_LS180_Human2.21342301
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.19972690
12DROSHA_22980978_ChIP-Seq_HELA_Human2.11463047
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.09718426
14AR_21572438_ChIP-Seq_LNCaP_Human2.09406936
15EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.07123575
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.0113681
17FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.99989565
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.97079912
19CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.90778779
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.88541276
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.85706175
22NFE2_27457419_Chip-Seq_LIVER_Mouse1.78926625
23NR3C1_21868756_ChIP-Seq_MCF10A_Human1.76522796
24ELK4_26923725_Chip-Seq_MESODERM_Mouse1.75333726
25P300_19829295_ChIP-Seq_ESCs_Human1.72451441
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.71578923
27PCGF2_27294783_Chip-Seq_NPCs_Mouse1.69752246
28TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.69701336
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69663406
30SUZ12_27294783_Chip-Seq_NPCs_Mouse1.68826560
31STAT1_17558387_ChIP-Seq_HELA_Human1.66730378
32FUS_26573619_Chip-Seq_HEK293_Human1.60920608
33GBX2_23144817_ChIP-Seq_PC3_Human1.59681783
34SMAD4_21799915_ChIP-Seq_A2780_Human1.59122717
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58572604
36BCAT_22108803_ChIP-Seq_LS180_Human1.58410991
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.56765872
38TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56378925
39WDR5_24793694_ChIP-Seq_LNCAP_Human1.55739689
40TAL1_26923725_Chip-Seq_HPCs_Mouse1.55067459
41KAP1_22055183_ChIP-Seq_ESCs_Mouse1.54661327
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53466939
43KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.52821978
44* STAT3_23295773_ChIP-Seq_U87_Human1.51871794
45SMAD4_21741376_ChIP-Seq_EPCs_Human1.46874435
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.46807676
47NANOG_19829295_ChIP-Seq_ESCs_Human1.45249645
48SOX2_19829295_ChIP-Seq_ESCs_Human1.45249645
49CBX2_27304074_Chip-Seq_ESCs_Mouse1.44522084
50ARNT_22903824_ChIP-Seq_MCF-7_Human1.44024882
51ZNF274_21170338_ChIP-Seq_K562_Hela1.43142953
52TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41425787
53TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.41117986
54CBP_20019798_ChIP-Seq_JUKART_Human1.40595241
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40595241
56FOXM1_26456572_ChIP-Seq_MCF-7_Human1.40130554
57E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39384868
58FOXA1_25329375_ChIP-Seq_VCAP_Human1.39030083
59FOXA1_27270436_Chip-Seq_PROSTATE_Human1.39030083
60AHR_22903824_ChIP-Seq_MCF-7_Human1.39025472
61AR_25329375_ChIP-Seq_VCAP_Human1.37767951
62MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.37563244
63KDM2B_26808549_Chip-Seq_REH_Human1.36423671
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36182727
65POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.36182727
66SOX2_22085726_ChIP-Seq_NPCs_Mouse1.35702181
67* TCF4_22108803_ChIP-Seq_LS180_Human1.35403666
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.35051063
69PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34282373
70ETV1_20927104_ChIP-Seq_GIST48_Human1.33458759
71FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33059588
72GATA3_21867929_ChIP-Seq_CD8_Mouse1.32121487
73TAF15_26573619_Chip-Seq_HEK293_Human1.31305119
74RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.31243760
75NANOG_18555785_Chip-Seq_ESCs_Mouse1.30374578
76ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29463748
77ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.27871833
78ESR1_20079471_ChIP-ChIP_T-47D_Human1.27864805
79EZH2_27294783_Chip-Seq_NPCs_Mouse1.27004822
80PHF8_20622853_ChIP-Seq_HELA_Human1.26750306
81NCOR_22424771_ChIP-Seq_293T_Human1.26535784
82P53_22387025_ChIP-Seq_ESCs_Mouse1.25331238
83PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.24254778
84EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23844470
85OCT4_18555785_Chip-Seq_ESCs_Mouse1.23651831
86CRX_20693478_ChIP-Seq_RETINA_Mouse1.23467563
87TP63_23658742_ChIP-Seq_EP156T_Human1.22742313
88HOXB7_26014856_ChIP-Seq_BT474_Human1.22459130
89SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.21746095
90GF1_26923725_Chip-Seq_HPCs_Mouse1.21290765
91AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.20744826
92STAT1_20625510_ChIP-Seq_HELA_Human1.20482367
93RUNX2_22187159_ChIP-Seq_PCA_Human1.20359446
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19256514
95RNF2_27304074_Chip-Seq_NSC_Mouse1.18869320
96PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18289060
97EWS_26573619_Chip-Seq_HEK293_Human1.17868938
98HNFA_21074721_ChIP-Seq_CACO-2_Human1.16376061
99STAT3_18555785_Chip-Seq_ESCs_Mouse1.16371689
100* PRDM14_20953172_ChIP-Seq_ESCs_Human1.15833785
101UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15725545
102GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.15709234
103KLF4_18555785_Chip-Seq_ESCs_Mouse1.15254935
104RUNX1_26923725_Chip-Seq_HPCs_Mouse1.15097208
105RBPJ_21746931_ChIP-Seq_IB4_Human1.14852806
106SMAD3_21741376_ChIP-Seq_HESCs_Human1.14726997
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14460561
108TDRD3_21172665_ChIP-Seq_MCF-7_Human1.14454280
109FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14398113
110AR_20517297_ChIP-Seq_VCAP_Human1.14297161
111P300_18555785_Chip-Seq_ESCs_Mouse1.14239361
112SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.13339151
113EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.13079681
114EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.13028857
115CTBP2_25329375_ChIP-Seq_LNCAP_Human1.12339052
116PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.12133721
117CDX2_22108803_ChIP-Seq_LS180_Human1.12093132
118NFYA_21822215_ChIP-Seq_K562_Human1.12090207
119FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.11450638
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10952377
121CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.10669880
122FOXA1_21572438_ChIP-Seq_LNCaP_Human1.10391797
123CBX2_22325352_ChIP-Seq_293T-Rex_Human1.10378004
124* GATA3_21878914_ChIP-Seq_MCF-7_Human1.10359679
125SALL1_21062744_ChIP-ChIP_HESCs_Human1.10250635
126SMAD4_21741376_ChIP-Seq_HESCs_Human1.10217796
127ESRRB_18555785_Chip-Seq_ESCs_Mouse1.10098285
128RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10045568
129SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10006021
130GATA3_21867929_ChIP-Seq_TH1_Mouse1.09725500
131* SMRT_27268052_Chip-Seq_Bcells_Human1.09470213
132* REST_21632747_ChIP-Seq_MESCs_Mouse1.09199188
133TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09017828
134CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.08731746
135SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.08692836
136OCT4_21477851_ChIP-Seq_ESCs_Mouse1.08592260
137CMYC_18555785_Chip-Seq_ESCs_Mouse1.08442520
138EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07553250
139* TP53_18474530_ChIP-ChIP_U2OS_Human1.06432246
140ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06425573
141PU1_27457419_Chip-Seq_LIVER_Mouse1.06037460
142CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06020710
143HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05767367
144* MYC_19829295_ChIP-Seq_ESCs_Human1.05399136
145CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04492765
146NANOG_20526341_ChIP-Seq_ESCs_Human1.04430388
147TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.04004870
148* FOXA1_25552417_ChIP-Seq_VCAP_Human1.03834822
149P53_21459846_ChIP-Seq_SAOS-2_Human1.03276420
150PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.02963283
151FLI1_21867929_ChIP-Seq_TH2_Mouse1.02387585
152E2F1_18555785_Chip-Seq_ESCs_Mouse1.01259556
153PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.00670056
154RUNX1_27457419_Chip-Seq_LIVER_Mouse1.00576433
155ZFX_18555785_Chip-Seq_ESCs_Mouse0.98779748
156CTCF_18555785_Chip-Seq_ESCs_Mouse0.98068557
157SOX2_18555785_Chip-Seq_ESCs_Mouse0.97526069
158NMYC_18555785_Chip-Seq_ESCs_Mouse0.97015700
159NFYB_21822215_ChIP-Seq_K562_Human0.95797888
160* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.95376580
161GF1B_26923725_Chip-Seq_HPCs_Mouse0.94460924
162LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.92972746
163PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.92373779
164TBL1_22424771_ChIP-Seq_293T_Human0.91953778
165ER_23166858_ChIP-Seq_MCF-7_Human0.91138587
166SMAD1_18555785_Chip-Seq_ESCs_Mouse0.90733466
167ERG_20517297_ChIP-Seq_VCAP_Human0.90114855
168PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89504871
169ESET_19884257_ChIP-Seq_ESCs_Mouse0.89359618
170SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89192608
171* TCF4_23295773_ChIP-Seq_U87_Human0.87347728
172SPI1_26923725_Chip-Seq_HPCs_Mouse0.85372333
173LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.85370068

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.81556399
2MP0001929_abnormal_gametogenesis5.40924553
3MP0008875_abnormal_xenobiotic_pharmacok4.95384338
4MP0008877_abnormal_DNA_methylation4.81847530
5MP0002210_abnormal_sex_determination3.74814120
6MP0004043_abnormal_pH_regulation3.65009587
7MP0002837_dystrophic_cardiac_calcinosis3.40729889
8MP0002161_abnormal_fertility/fecundity3.15477556
9MP0001145_abnormal_male_reproductive3.08082351
10MP0003136_yellow_coat_color3.04764139
11MP0002653_abnormal_ependyma_morphology3.00162292
12MP0008789_abnormal_olfactory_epithelium2.80406446
13MP0000653_abnormal_sex_gland2.71869125
14MP0005083_abnormal_biliary_tract2.51474570
15MP0005670_abnormal_white_adipose2.33494341
16MP0002160_abnormal_reproductive_system2.22174768
17MP0005365_abnormal_bile_salt2.17226961
18MP0002277_abnormal_respiratory_mucosa2.15505983
19MP0003195_calcinosis2.13753660
20MP0005085_abnormal_gallbladder_physiolo2.08735331
21MP0005410_abnormal_fertilization14.9269217
22MP0005499_abnormal_olfactory_system1.91031471
23MP0005394_taste/olfaction_phenotype1.91031471
24MP0002168_other_aberrant_phenotype1.85783250
25MP0008058_abnormal_DNA_repair1.77382878
26MP0003646_muscle_fatigue1.77171350
27MP0009780_abnormal_chondrocyte_physiolo1.75242714
28MP0002909_abnormal_adrenal_gland1.71958366
29MP0005171_absent_coat_pigmentation1.70495630
30MP0002822_catalepsy1.67277713
31MP0005395_other_phenotype1.59943339
32MP0000383_abnormal_hair_follicle1.58823208
33MP0005623_abnormal_meninges_morphology1.44884560
34MP0010094_abnormal_chromosome_stability1.37770474
35MP0008057_abnormal_DNA_replication1.36055282
36MP0002282_abnormal_trachea_morphology1.33454835
37MP0002876_abnormal_thyroid_physiology1.27439333
38MP0006072_abnormal_retinal_apoptosis1.24856533
39MP0001984_abnormal_olfaction1.22414066
40MP0008995_early_reproductive_senescence1.21223657
41MP0008872_abnormal_physiological_respon1.21035245
42MP0005389_reproductive_system_phenotype1.20360651
43MP0010678_abnormal_skin_adnexa1.14946307
44MP0002735_abnormal_chemical_nociception1.13418631
45MP0001485_abnormal_pinna_reflex1.08075975
46MP0008007_abnormal_cellular_replicative1.07446995
47MP0002734_abnormal_mechanical_nocicepti1.06703420
48MP0009745_abnormal_behavioral_response1.06213362
49MP0003111_abnormal_nucleus_morphology1.04873232
50MP0005647_abnormal_sex_gland1.04028861
51MP0001486_abnormal_startle_reflex1.01700860
52MP0003878_abnormal_ear_physiology1.00809700
53MP0005377_hearing/vestibular/ear_phenot1.00809700
54MP0005195_abnormal_posterior_eye1.00754402
55MP0002272_abnormal_nervous_system0.99078370
56MP0001346_abnormal_lacrimal_gland0.98901307
57MP0003252_abnormal_bile_duct0.97960141
58MP0002229_neurodegeneration0.96588480
59MP0009697_abnormal_copulation0.95710973
60MP0000631_abnormal_neuroendocrine_gland0.94367349
61MP0002102_abnormal_ear_morphology0.94119951
62MP0004233_abnormal_muscle_weight0.93157904
63MP0003011_delayed_dark_adaptation0.90943555
64MP0005084_abnormal_gallbladder_morpholo0.89645680
65MP0010030_abnormal_orbit_morphology0.89426035
66MP0002233_abnormal_nose_morphology0.89169372
67MP0003786_premature_aging0.88870615
68MP0001986_abnormal_taste_sensitivity0.88510533
69MP0001501_abnormal_sleep_pattern0.85425368
70MP0000569_abnormal_digit_pigmentation0.84756610
71MP0001765_abnormal_ion_homeostasis0.83684594
72MP0000427_abnormal_hair_cycle0.82970439
73MP0005248_abnormal_Harderian_gland0.82421155
74MP0005220_abnormal_exocrine_pancreas0.81868349
75MP0009046_muscle_twitch0.76573747
76MP0003787_abnormal_imprinting0.76296383
77MP0002572_abnormal_emotion/affect_behav0.74808028
78MP0001119_abnormal_female_reproductive0.73462602
79MP0001970_abnormal_pain_threshold0.71297810
80MP0002557_abnormal_social/conspecific_i0.71045819
81MP0002928_abnormal_bile_duct0.70673924
82MP0002938_white_spotting0.69140248
83MP0001529_abnormal_vocalization0.68892028
84MP0000566_synostosis0.67916491
85MP0004808_abnormal_hematopoietic_stem0.67743325
86MP0001944_abnormal_pancreas_morphology0.67482173
87MP0001293_anophthalmia0.67309910
88MP0001545_abnormal_hematopoietic_system0.66520802
89MP0005397_hematopoietic_system_phenotyp0.66520802
90MP0002752_abnormal_somatic_nervous0.65448825
91MP0004885_abnormal_endolymph0.64630947
92MP0002132_abnormal_respiratory_system0.64453112
93MP0003137_abnormal_impulse_conducting0.61882986
94MP0006276_abnormal_autonomic_nervous0.61692254
95MP0004142_abnormal_muscle_tone0.61086561
96MP0005646_abnormal_pituitary_gland0.60028132
97MP0003699_abnormal_female_reproductive0.59222922
98MP0005253_abnormal_eye_physiology0.58285068
99MP0001324_abnormal_eye_pigmentation0.52054882
100MP0003115_abnormal_respiratory_system0.51735089
101MP0003183_abnormal_peptide_metabolism0.51301157
102MP0003943_abnormal_hepatobiliary_system0.49977830
103MP0005174_abnormal_tail_pigmentation0.48894692
104MP0003693_abnormal_embryo_hatching0.48477954
105MP0005551_abnormal_eye_electrophysiolog0.48221558
106MP0001764_abnormal_homeostasis0.47969249
107MP0000015_abnormal_ear_pigmentation0.47698134
108MP0003077_abnormal_cell_cycle0.46293728
109MP0003950_abnormal_plasma_membrane0.46027582
110MP0006292_abnormal_olfactory_placode0.44779218
111MP0002234_abnormal_pharynx_morphology0.43590393
112MP0001835_abnormal_antigen_presentation0.42750680
113MP0004742_abnormal_vestibular_system0.42531654
114MP0000358_abnormal_cell_content/0.42411495
115MP0005391_vision/eye_phenotype0.40705656
116MP0001873_stomach_inflammation0.40446151
117MP0002736_abnormal_nociception_after0.39900322
118MP0009278_abnormal_bone_marrow0.39119758
119MP0003879_abnormal_hair_cell0.37623959
120MP0000313_abnormal_cell_death0.36356845
121MP0002009_preneoplasia0.36119804
122MP0002405_respiratory_system_inflammati0.33669658
123MP0002163_abnormal_gland_morphology0.31039123
124MP0004134_abnormal_chest_morphology0.29200013
125MP0005636_abnormal_mineral_homeostasis0.28959378
126MP0004133_heterotaxia0.27463690
127MP0003942_abnormal_urinary_system0.26927651
128MP0009115_abnormal_fat_cell0.25516036
129MP0000026_abnormal_inner_ear0.25511311
130MP0001919_abnormal_reproductive_system0.24891388
131MP0010307_abnormal_tumor_latency0.24260597
132MP0004019_abnormal_vitamin_homeostasis0.24078936
133MP0001963_abnormal_hearing_physiology0.23388747
134MP0005075_abnormal_melanosome_morpholog0.21597755
135MP0003936_abnormal_reproductive_system0.21376840
136MP0001270_distended_abdomen0.21124714
137MP0002109_abnormal_limb_morphology0.21074565
138MP0003861_abnormal_nervous_system0.21066100
139MP0009785_altered_susceptibility_to0.19739114
140MP0005503_abnormal_tendon_morphology0.19624068
141MP0005379_endocrine/exocrine_gland_phen0.19517518
142MP0004036_abnormal_muscle_relaxation0.19254656
143MP0003890_abnormal_embryonic-extraembry0.18909700
144MP0000678_abnormal_parathyroid_gland0.18844012
145MP0003718_maternal_effect0.17938798
146MP0001968_abnormal_touch/_nociception0.17486761
147MP0001502_abnormal_circadian_rhythm0.17124454
148MP0002169_no_abnormal_phenotype0.16807267
149MP0002873_normal_phenotype0.16685685
150MP0003045_fibrosis0.16468904
151MP0002638_abnormal_pupillary_reflex0.15600172
152MP0000432_abnormal_head_morphology0.15168398

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.04463445
2Abnormal respiratory epithelium morphology (HP:0012253)8.79173671
3Abnormal respiratory motile cilium morphology (HP:0005938)8.79173671
4Rhinitis (HP:0012384)7.59606008
5Abnormal ciliary motility (HP:0012262)7.33275361
6Chronic bronchitis (HP:0004469)6.78050475
7Infertility (HP:0000789)6.26591439
8Nasal polyposis (HP:0100582)5.88979756
9Abnormality of the nasal mucosa (HP:0000433)4.87287890
10Nephronophthisis (HP:0000090)4.75051025
11Bronchiectasis (HP:0002110)4.55133868
12Bronchitis (HP:0012387)4.32119400
13Abnormality of the renal medulla (HP:0100957)3.73310302
14Male infertility (HP:0003251)3.46938750
15Gonadotropin excess (HP:0000837)3.34231327
16Abnormal spermatogenesis (HP:0008669)3.27808404
17Tubulointerstitial nephritis (HP:0001970)3.25862156
18Recurrent sinusitis (HP:0011108)3.19676313
19Recurrent otitis media (HP:0000403)3.11537346
20Molar tooth sign on MRI (HP:0002419)2.80969877
21Abnormality of midbrain morphology (HP:0002418)2.80969877
22Impulsivity (HP:0100710)2.75151538
23Recurrent bronchitis (HP:0002837)2.68165350
24Medial flaring of the eyebrow (HP:0010747)2.62378756
25Hyperactive renin-angiotensin system (HP:0000841)2.56907206
26Tubulointerstitial abnormality (HP:0001969)2.51766235
27Tubular atrophy (HP:0000092)2.50333373
28Absent rod-and cone-mediated responses on ERG (HP:0007688)2.46964054
29Postaxial foot polydactyly (HP:0001830)2.43356267
30Azoospermia (HP:0000027)2.40372088
31Anencephaly (HP:0002323)2.35175907
32Chronic otitis media (HP:0000389)2.33094948
33Hypoplasia of the capital femoral epiphysis (HP:0003090)2.26658526
34Abnormal rod and cone electroretinograms (HP:0008323)2.21073119
35Decreased circulating renin level (HP:0003351)2.20715650
36Congenital hepatic fibrosis (HP:0002612)2.18722646
37Sclerocornea (HP:0000647)2.17156570
38Dyschromatopsia (HP:0007641)2.14522621
39Hyperkalemia (HP:0002153)2.07107731
40Male pseudohermaphroditism (HP:0000037)2.05646852
41Fibular hypoplasia (HP:0003038)2.04331398
42Abnormality of the renal cortex (HP:0011035)2.03231502
43Stage 5 chronic kidney disease (HP:0003774)2.03042767
44Bony spicule pigmentary retinopathy (HP:0007737)2.02140262
45Atelectasis (HP:0100750)2.01082859
46Bile duct proliferation (HP:0001408)2.00822901
47Abnormal biliary tract physiology (HP:0012439)2.00822901
48Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.7253035
49Dynein arm defect of respiratory motile cilia (HP:0012255)12.4518032
50Absent/shortened dynein arms (HP:0200106)12.4518032
51Furrowed tongue (HP:0000221)1.94841566
52Impaired proprioception (HP:0010831)1.92830455
53Abnormality of the dental root (HP:0006486)1.92272140
54Taurodontia (HP:0000679)1.92272140
55Abnormality of permanent molar morphology (HP:0011071)1.92272140
56Renal dysplasia (HP:0000110)1.91020403
57Abnormality of macular pigmentation (HP:0008002)1.89334487
58Supernumerary spleens (HP:0009799)1.87644802
59Aplasia/Hypoplasia of the spleen (HP:0010451)1.87394214
60Genital tract atresia (HP:0001827)1.86907329
61Renal salt wasting (HP:0000127)1.86243316
62Absent epiphyses (HP:0010577)1.86147481
63Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.86147481
64Bell-shaped thorax (HP:0001591)1.85059321
65Abnormality of molar (HP:0011077)1.84587119
66Abnormality of molar morphology (HP:0011070)1.84587119
67Vaginal atresia (HP:0000148)1.83133367
68Asplenia (HP:0001746)1.82352983
69Abnormality of the lower motor neuron (HP:0002366)1.82219129
70Tubulointerstitial fibrosis (HP:0005576)1.81729998
71Polydipsia (HP:0001959)1.81122948
72Abnormal drinking behavior (HP:0030082)1.81122948
73Hyperaldosteronism (HP:0000859)1.79189835
74Decreased central vision (HP:0007663)1.78683848
75Facial cleft (HP:0002006)1.78069495
76Amelogenesis imperfecta (HP:0000705)1.77636859
77Pancreatic fibrosis (HP:0100732)1.77029940
78True hermaphroditism (HP:0010459)1.73877315
79Abnormality of the dental pulp (HP:0006479)1.72824917
80Postaxial hand polydactyly (HP:0001162)1.71477689
81Abdominal situs inversus (HP:0003363)1.71032001
82Abnormality of abdominal situs (HP:0011620)1.71032001
83Retinitis pigmentosa (HP:0000510)1.70417725
84Abnormality of chloride homeostasis (HP:0011422)1.67980936
85Short ribs (HP:0000773)1.67423829
86Oculomotor apraxia (HP:0000657)1.67243356
87Short thorax (HP:0010306)1.67027129
88Median cleft lip (HP:0000161)1.64500045
89Preaxial hand polydactyly (HP:0001177)1.63664555
90Congenital stationary night blindness (HP:0007642)1.62662996
91Heterotopia (HP:0002282)1.61795665
92J-shaped sella turcica (HP:0002680)1.61624198
93Cone-rod dystrophy (HP:0000548)1.60965334
94Absent frontal sinuses (HP:0002688)1.59059306
95Cystic liver disease (HP:0006706)1.58703142
96Chronic sinusitis (HP:0011109)1.57971811
97Aplasia/Hypoplasia of the tongue (HP:0010295)1.56844423
98Poor coordination (HP:0002370)1.56312045
99Spastic tetraparesis (HP:0001285)1.54169356
100Nephropathy (HP:0000112)1.54134912
101Absent speech (HP:0001344)1.54007240
102Abnormality of dentin (HP:0010299)1.53610688
103Cholecystitis (HP:0001082)1.50868954
104Abnormal gallbladder physiology (HP:0012438)1.50868954
105Abnormality of renal excretion (HP:0011036)1.50823755
106Choroideremia (HP:0001139)1.49784189
107Abolished electroretinogram (ERG) (HP:0000550)1.49534987
108Congenital primary aphakia (HP:0007707)1.48025553
109Microglossia (HP:0000171)1.47372933
110Pancreatic cysts (HP:0001737)1.46974746
111Hypokalemic alkalosis (HP:0001949)1.45120208
112Short femoral neck (HP:0100864)1.44548630
113Aplasia/Hypoplasia of the lens (HP:0008063)1.44501645
114Abnormality of renin-angiotensin system (HP:0000847)1.44293827
115Central scotoma (HP:0000603)1.43778831
116Deformed sella turcica (HP:0002681)1.43575109
117Gait imbalance (HP:0002141)1.42231767
118Chronic hepatic failure (HP:0100626)1.41036935
119Amyotrophic lateral sclerosis (HP:0007354)1.41028818
120Attenuation of retinal blood vessels (HP:0007843)1.36884652
121Nephrogenic diabetes insipidus (HP:0009806)1.36196608
122Severe visual impairment (HP:0001141)1.34918989
123Constricted visual fields (HP:0001133)1.34142153
124Sloping forehead (HP:0000340)1.33776265
125Pendular nystagmus (HP:0012043)1.32654125
126Posterior subcapsular cataract (HP:0007787)1.32356118
127Optic neuritis (HP:0100653)1.31841215
128Retrobulbar optic neuritis (HP:0100654)1.31841215
129Occipital encephalocele (HP:0002085)1.31578684
130Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.29919485
131Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.28232775
132Polyuria (HP:0000103)1.28161949
133Nephroblastoma (Wilms tumor) (HP:0002667)1.28092931
134Scotoma (HP:0000575)1.26515608
135Type II lissencephaly (HP:0007260)1.25949564
136Aplasia/Hypoplasia of the fibula (HP:0006492)1.25615725
137Abnormality of the anterior horn cell (HP:0006802)1.25077820
138Degeneration of anterior horn cells (HP:0002398)1.25077820
139Aplasia/Hypoplasia of the uvula (HP:0010293)1.24413650
140Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.22387913
141Multicystic kidney dysplasia (HP:0000003)1.22142802
142Ectopic kidney (HP:0000086)1.21537653
143Portal hypertension (HP:0001409)1.18757862
144Prominent nasal bridge (HP:0000426)1.16507326
145Aganglionic megacolon (HP:0002251)1.14785400
146Disproportionate short-trunk short stature (HP:0003521)1.13824556

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.94149975
2PDK37.94149975
3TESK15.63361901
4PDK25.30715841
5PRKD34.68625019
6FRK4.06368426
7ICK3.81260634
8MST43.63942989
9MAP4K22.64058632
10PTK2B2.38110039
11PNCK2.13188939
12EPHA22.09015084
13NME12.02891989
14NEK22.01472507
15WNK41.98666971
16STK381.82099530
17STK391.81198348
18ACVR1B1.79825766
19MAPKAPK31.75913003
20LATS21.57805878
21WNK31.49051602
22BCR1.43737186
23WNK11.31841978
24MAP3K21.29731365
25CAMKK21.28879079
26STK31.27185833
27MAPK151.26567424
28BMPR1B1.22106612
29PINK11.19720598
30DYRK1B1.17507500
31TLK11.16893551
32OXSR11.15286587
33MAP3K41.14256844
34CCNB11.13734164
35STK38L1.07671439
36PRKCI1.07433016
37PASK1.04581420
38DYRK30.93806601
39MAPK130.90701530
40EIF2AK30.89389464
41CHEK20.89265702
42PRKAA20.88951975
43PDK10.88790987
44FER0.86634775
45NEK60.86381240
46IRAK10.85242866
47MUSK0.83553586
48TAF10.79827257
49PLK40.79481492
50TTK0.76586565
51TRIM280.72297868
52NLK0.70926526
53ATR0.68068426
54RIPK40.65695165
55NUAK10.64818842
56ADRBK10.64702824
57MAP3K70.64345518
58CSNK1A1L0.64333509
59TGFBR10.64064878
60PRKCE0.61504177
61CDC70.60699986
62MAP2K20.57250148
63CHEK10.54671640
64ERBB20.52412128
65MAP2K60.52281608
66LRRK20.51635126
67CASK0.51307672
68BMPR20.48572461
69CDK30.47586334
70PIK3CG0.47214927
71YES10.46213667
72ATM0.45937437
73STK100.45023726
74RPS6KB10.44711318
75FGFR20.43988100
76MELK0.43179567
77TYRO30.42637123
78PRKACA0.42493394
79ADRBK20.42046847
80CAMK1G0.41988752
81EPHA40.41962298
82CAMKK10.41877177
83STK110.39986876
84PAK30.39704224
85WEE10.39599324
86CSNK1G20.39136624
87CAMK2A0.38650253
88SMG10.38599373
89TXK0.37843754
90STK160.37474945
91PHKG10.36780947
92PHKG20.36780947
93IRAK20.36062405
94VRK20.36035428
95PDPK10.35416184
96PRKG20.34655412
97SRPK10.34627563
98MAPKAPK50.34131363
99AURKA0.33740890
100TRPM70.33727131
101PRKCQ0.32267521
102CDK120.32176403
103PLK10.30926298
104OBSCN0.28996434
105CSNK1G30.28870951
106CSNK1G10.28345727
107CSK0.28293978
108PLK20.27996507
109NTRK20.27435026
110BRAF0.26974963
111PAK10.24523059
112STK240.24385051
113PRKAA10.23574105
114PRKCA0.23254479
115CDK190.22343409
116ZAK0.22175561
117PIM10.21989694
118MAP2K70.21807846
119DYRK20.21377572
120EIF2AK20.20616375
121CSNK1A10.20371897
122DAPK20.20139290
123MET0.19887996
124TNIK0.18426472
125PRKCG0.18326621
126LMTK20.16489510
127CSNK2A10.14588884
128CDK90.14283090
129MTOR0.13626048
130MAP3K140.11871131
131CDK40.10410324
132INSRR0.10017785
133SGK20.09064114
134VRK10.08710222
135CDK80.08667521
136BRSK20.08473638
137TIE10.08215117
138GSK3B0.07694064
139PRKG10.07560384
140ERBB30.07101413
141EEF2K0.06182733
142MKNK20.05432399
143LATS10.05371983
144TNK20.05292282
145CSF1R0.05292032
146CDK10.04817881
147KIT0.04672723
148CDK70.04154237
149IKBKB0.04050902
150TEC0.03819755
151CDK20.03642974
152STK40.03221686
153GRK10.02830129
154PRKACB0.02555181
155RPS6KA10.02217617
156MAPK80.02027677
157TGFBR20.02025251
158PAK40.01990366
159CHUK0.01701234
160SGK30.01177574

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.75540331
2Basal transcription factors_Homo sapiens_hsa030223.67637375
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.56990202
4Fanconi anemia pathway_Homo sapiens_hsa034603.47329994
5Fatty acid biosynthesis_Homo sapiens_hsa000613.39810839
6Histidine metabolism_Homo sapiens_hsa003403.37305612
7Phototransduction_Homo sapiens_hsa047443.16269595
8Phenylalanine metabolism_Homo sapiens_hsa003602.99972916
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.89521228
10Pyruvate metabolism_Homo sapiens_hsa006202.86184933
11Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.80843228
12Linoleic acid metabolism_Homo sapiens_hsa005912.75457161
13beta-Alanine metabolism_Homo sapiens_hsa004102.71442033
14Caffeine metabolism_Homo sapiens_hsa002322.53827786
15Glucagon signaling pathway_Homo sapiens_hsa049222.40842818
16Tyrosine metabolism_Homo sapiens_hsa003502.34733999
17Dorso-ventral axis formation_Homo sapiens_hsa043202.26489493
18Propanoate metabolism_Homo sapiens_hsa006402.17100738
19Selenocompound metabolism_Homo sapiens_hsa004502.13114397
20Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.08260669
21Retinol metabolism_Homo sapiens_hsa008302.01473287
22Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.94679830
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.88519565
24Nicotine addiction_Homo sapiens_hsa050331.85042547
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.84176393
26Carbohydrate digestion and absorption_Homo sapiens_hsa049731.77857993
27Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.76409799
28Oocyte meiosis_Homo sapiens_hsa041141.68645462
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64863300
30Butanoate metabolism_Homo sapiens_hsa006501.64267799
31Glycerolipid metabolism_Homo sapiens_hsa005611.63363199
32Steroid hormone biosynthesis_Homo sapiens_hsa001401.60593467
33mRNA surveillance pathway_Homo sapiens_hsa030151.58693925
34Fructose and mannose metabolism_Homo sapiens_hsa000511.51569961
35Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.49681652
36RNA transport_Homo sapiens_hsa030131.47645806
37Primary bile acid biosynthesis_Homo sapiens_hsa001201.46368255
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.44862174
39Pentose phosphate pathway_Homo sapiens_hsa000301.43828709
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.43470403
41Glycerophospholipid metabolism_Homo sapiens_hsa005641.42682975
42Amphetamine addiction_Homo sapiens_hsa050311.41208479
43Purine metabolism_Homo sapiens_hsa002301.41052452
44Peroxisome_Homo sapiens_hsa041461.38104774
45Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.36386695
46Huntingtons disease_Homo sapiens_hsa050161.36011870
47Glycosaminoglycan degradation_Homo sapiens_hsa005311.31775561
48Ether lipid metabolism_Homo sapiens_hsa005651.30920619
49Tryptophan metabolism_Homo sapiens_hsa003801.29516770
50Arachidonic acid metabolism_Homo sapiens_hsa005901.25448441
51Nitrogen metabolism_Homo sapiens_hsa009101.25148127
52Homologous recombination_Homo sapiens_hsa034401.23629174
53Maturity onset diabetes of the young_Homo sapiens_hsa049501.21051295
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.15474270
55Antigen processing and presentation_Homo sapiens_hsa046121.14490202
56Salivary secretion_Homo sapiens_hsa049701.11545375
57Mineral absorption_Homo sapiens_hsa049781.09398285
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08442042
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.07859235
60Legionellosis_Homo sapiens_hsa051341.07048489
61Pentose and glucuronate interconversions_Homo sapiens_hsa000401.04222126
62Renin secretion_Homo sapiens_hsa049241.01676964
63PPAR signaling pathway_Homo sapiens_hsa033201.01234589
64Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.98731789
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.97219718
66Circadian rhythm_Homo sapiens_hsa047100.96950356
67Cysteine and methionine metabolism_Homo sapiens_hsa002700.89472598
68Morphine addiction_Homo sapiens_hsa050320.87366325
69Measles_Homo sapiens_hsa051620.86909625
70ABC transporters_Homo sapiens_hsa020100.84139331
71Hedgehog signaling pathway_Homo sapiens_hsa043400.82458043
72RNA degradation_Homo sapiens_hsa030180.82171760
73Cell cycle_Homo sapiens_hsa041100.81576331
74Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.81535882
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79558062
76Ovarian steroidogenesis_Homo sapiens_hsa049130.78307196
77Pyrimidine metabolism_Homo sapiens_hsa002400.74067427
78Serotonergic synapse_Homo sapiens_hsa047260.71456115
79Taste transduction_Homo sapiens_hsa047420.70684296
80Calcium signaling pathway_Homo sapiens_hsa040200.69609254
81Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68879737
82Sphingolipid metabolism_Homo sapiens_hsa006000.68182211
83Influenza A_Homo sapiens_hsa051640.67980607
84Cardiac muscle contraction_Homo sapiens_hsa042600.67266654
85Non-homologous end-joining_Homo sapiens_hsa034500.67227425
86Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67024836
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65957595
88Glutamatergic synapse_Homo sapiens_hsa047240.65887967
89Tight junction_Homo sapiens_hsa045300.65215832
90Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65055453
91GABAergic synapse_Homo sapiens_hsa047270.64016924
92Oxidative phosphorylation_Homo sapiens_hsa001900.63439741
93Systemic lupus erythematosus_Homo sapiens_hsa053220.61782588
94Other glycan degradation_Homo sapiens_hsa005110.58177664
95N-Glycan biosynthesis_Homo sapiens_hsa005100.58032610
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57548624
97Mismatch repair_Homo sapiens_hsa034300.57503512
98Arginine and proline metabolism_Homo sapiens_hsa003300.57494850
99DNA replication_Homo sapiens_hsa030300.57025399
100Collecting duct acid secretion_Homo sapiens_hsa049660.56984803
101Herpes simplex infection_Homo sapiens_hsa051680.54780747
102Base excision repair_Homo sapiens_hsa034100.53690237
103Glutathione metabolism_Homo sapiens_hsa004800.52134485
104cGMP-PKG signaling pathway_Homo sapiens_hsa040220.52107656
105Starch and sucrose metabolism_Homo sapiens_hsa005000.51420366
106Chemical carcinogenesis_Homo sapiens_hsa052040.50916148
107Olfactory transduction_Homo sapiens_hsa047400.49686654
108Regulation of autophagy_Homo sapiens_hsa041400.49302373
109Fat digestion and absorption_Homo sapiens_hsa049750.46907339
110Inositol phosphate metabolism_Homo sapiens_hsa005620.45718332
111Insulin secretion_Homo sapiens_hsa049110.44336593
112Wnt signaling pathway_Homo sapiens_hsa043100.44238161
113Basal cell carcinoma_Homo sapiens_hsa052170.43767648
114Synaptic vesicle cycle_Homo sapiens_hsa047210.43244404
115Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43085967
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.42989661
117Fatty acid metabolism_Homo sapiens_hsa012120.42795347
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41729085
119Long-term potentiation_Homo sapiens_hsa047200.40961133
120Estrogen signaling pathway_Homo sapiens_hsa049150.40242848
121Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36662255
122Nucleotide excision repair_Homo sapiens_hsa034200.36368443
123B cell receptor signaling pathway_Homo sapiens_hsa046620.36123735
124Viral carcinogenesis_Homo sapiens_hsa052030.35970934
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35936392
126Epstein-Barr virus infection_Homo sapiens_hsa051690.35140157
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.34972614
128Sulfur metabolism_Homo sapiens_hsa009200.32698236
129Type I diabetes mellitus_Homo sapiens_hsa049400.32489619
130Bile secretion_Homo sapiens_hsa049760.32357739
131Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.31484715
132Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.30749203
133Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.30419051
134Alcoholism_Homo sapiens_hsa050340.29559866
135Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.29546503
136Carbon metabolism_Homo sapiens_hsa012000.28880636
137Jak-STAT signaling pathway_Homo sapiens_hsa046300.28577592
138Metabolic pathways_Homo sapiens_hsa011000.28116383
139Circadian entrainment_Homo sapiens_hsa047130.26996837
140Salmonella infection_Homo sapiens_hsa051320.26841172
141Drug metabolism - other enzymes_Homo sapiens_hsa009830.26467565
142Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.26302630
143Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.25176932
144Central carbon metabolism in cancer_Homo sapiens_hsa052300.24906525
145Fatty acid degradation_Homo sapiens_hsa000710.24350037
146cAMP signaling pathway_Homo sapiens_hsa040240.23487142
147Endocytosis_Homo sapiens_hsa041440.22909935
148Vascular smooth muscle contraction_Homo sapiens_hsa042700.22828710
149Protein export_Homo sapiens_hsa030600.22083838
150Transcriptional misregulation in cancer_Homo sapiens_hsa052020.22019316
151Cyanoamino acid metabolism_Homo sapiens_hsa004600.21843735
152Intestinal immune network for IgA production_Homo sapiens_hsa046720.20994510
153Vitamin digestion and absorption_Homo sapiens_hsa049770.20820260
154Hippo signaling pathway_Homo sapiens_hsa043900.20011384
155Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.18845323

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