CCDC68

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1bile acid and bile salt transport (GO:0015721)6.07159236
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)5.95210167
3angiotensin maturation (GO:0002003)5.82717783
4bundle of His cell to Purkinje myocyte communication (GO:0086069)5.06206059
5desmosome organization (GO:0002934)4.97138218
6cellular ketone body metabolic process (GO:0046950)4.77480548
7very-low-density lipoprotein particle assembly (GO:0034379)4.72654492
8epoxygenase P450 pathway (GO:0019373)4.69504712
9regulation of protein glycosylation (GO:0060049)4.66603840
10sulfur amino acid catabolic process (GO:0000098)4.66486679
11pyrimidine-containing compound transmembrane transport (GO:0072531)4.64087359
12lipoprotein transport (GO:0042953)4.44374110
13positive regulation of glycoprotein biosynthetic process (GO:0010560)4.37880546
14cellular glucuronidation (GO:0052695)4.36059734
15pantothenate metabolic process (GO:0015939)4.19782696
16NADH metabolic process (GO:0006734)4.18268671
17intestinal cholesterol absorption (GO:0030299)4.15302666
18glucuronate metabolic process (GO:0019585)4.12397576
19uronic acid metabolic process (GO:0006063)4.12397576
20ketone body metabolic process (GO:1902224)4.09098978
21purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.04981377
223-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.04981377
23hormone catabolic process (GO:0042447)4.02677585
24vitamin transmembrane transport (GO:0035461)4.00300741
25regulation of guanylate cyclase activity (GO:0031282)3.98699293
26cytidine deamination (GO:0009972)3.98328066
27cytidine metabolic process (GO:0046087)3.98328066
28cytidine catabolic process (GO:0006216)3.98328066
29plasma lipoprotein particle assembly (GO:0034377)3.91829932
30regulation of systemic arterial blood pressure by hormone (GO:0001990)3.90729022
31regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.90729022
32endocrine process (GO:0050886)3.90729022
33drug catabolic process (GO:0042737)3.89483885
34positive regulation of glycoprotein metabolic process (GO:1903020)3.88069211
35renal system process involved in regulation of blood volume (GO:0001977)3.88010229
36ethanol oxidation (GO:0006069)3.83729848
37urea metabolic process (GO:0019627)3.80958806
38urea cycle (GO:0000050)3.80209008
39intestinal absorption (GO:0050892)3.74500273
40calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.70543542
41negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)3.67549130
42protein-lipid complex assembly (GO:0065005)3.65675103
43coenzyme A biosynthetic process (GO:0015937)3.64148399
44negative regulation of sterol transport (GO:0032372)3.62516038
45negative regulation of cholesterol transport (GO:0032375)3.62516038
46maintenance of gastrointestinal epithelium (GO:0030277)3.61274006
47ribonucleoside bisphosphate biosynthetic process (GO:0034030)3.58281864
48nucleoside bisphosphate biosynthetic process (GO:0033866)3.58281864
49purine nucleoside bisphosphate biosynthetic process (GO:0034033)3.58281864
50fat-soluble vitamin biosynthetic process (GO:0042362)3.55315542
51negative regulation of complement activation (GO:0045916)3.53660214
52midgut development (GO:0007494)3.53376751
53actin filament depolymerization (GO:0030042)3.52601098
54drug transmembrane transport (GO:0006855)3.52376856
55erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.50462950
56L-phenylalanine catabolic process (GO:0006559)3.50462950
57nitrogen cycle metabolic process (GO:0071941)3.49903679
58renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.49519441
59negative regulation of protein activation cascade (GO:2000258)3.49151687
60flavonoid metabolic process (GO:0009812)3.47693661
61positive regulation of protein targeting to membrane (GO:0090314)3.47215056
62L-phenylalanine metabolic process (GO:0006558)3.46426888
63erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.46426888
64response to water (GO:0009415)3.44532729
65regulation of cholesterol homeostasis (GO:2000188)3.42925022
66thrombin receptor signaling pathway (GO:0070493)3.42547687
67regulation of systemic arterial blood pressure (GO:0003073)3.41251872
68ribonucleoside bisphosphate metabolic process (GO:0033875)3.39123937
69nucleoside bisphosphate metabolic process (GO:0033865)3.39123937
70purine nucleoside bisphosphate metabolic process (GO:0034032)3.39123937
71regulation of protein activation cascade (GO:2000257)3.38538159
72adhesion of symbiont to host cell (GO:0044650)3.35634973
73virion attachment to host cell (GO:0019062)3.35634973
74bile acid metabolic process (GO:0008206)3.35538814
75regulation of complement activation (GO:0030449)3.35362825
76lipoprotein metabolic process (GO:0042157)3.32387072
77positive regulation of guanylate cyclase activity (GO:0031284)3.24650726
78lung vasculature development (GO:0060426)3.23747862
79macrophage chemotaxis (GO:0048246)3.22710914
80regulation of cGMP biosynthetic process (GO:0030826)3.17564221
81drug metabolic process (GO:0017144)3.16258457
82regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.16013455
83phospholipid efflux (GO:0033700)3.15680605
84adhesion of symbiont to host (GO:0044406)3.14801236
85epithelial structure maintenance (GO:0010669)3.12281073
86cell adhesion mediated by integrin (GO:0033627)3.10501371
87peptide catabolic process (GO:0043171)3.10163919
88protein carboxylation (GO:0018214)3.09747125
89peptidyl-glutamic acid carboxylation (GO:0017187)3.09747125
90intestinal epithelial cell development (GO:0060576)3.07569717
91negative regulation of protein tyrosine kinase activity (GO:0061099)3.06731550
92high-density lipoprotein particle remodeling (GO:0034375)3.05501824
93protein-lipid complex remodeling (GO:0034368)3.05084154
94macromolecular complex remodeling (GO:0034367)3.05084154
95plasma lipoprotein particle remodeling (GO:0034369)3.05084154
96triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.03706987
97exogenous drug catabolic process (GO:0042738)3.03144801
98hemidesmosome assembly (GO:0031581)3.01003558
99drug transport (GO:0015893)2.98309355
100regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.98018460
101fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.97606964
102renal filtration (GO:0097205)2.94890149
103thyroid hormone metabolic process (GO:0042403)2.93776852
104ethanol metabolic process (GO:0006067)2.93421789
105glomerular filtration (GO:0003094)2.92910261
106receptor guanylyl cyclase signaling pathway (GO:0007168)2.92744070
107regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.92075095
108aromatic amino acid family catabolic process (GO:0009074)2.92021995
109phosphatidylcholine biosynthetic process (GO:0006656)2.90961932
110cholesterol efflux (GO:0033344)2.90804373
111plasma lipoprotein particle organization (GO:0071827)2.90785828
112diacylglycerol metabolic process (GO:0046339)2.90255327
113sulfate transmembrane transport (GO:1902358)2.89696215
114regulation of cholesterol esterification (GO:0010872)2.86847056
115nucleotide-sugar biosynthetic process (GO:0009226)2.86638274
116negative regulation of protein autophosphorylation (GO:0031953)2.86396399
117antibacterial humoral response (GO:0019731)2.86351111
118thyroid hormone generation (GO:0006590)2.86222011
119pyrimidine ribonucleoside catabolic process (GO:0046133)2.86209655
120polyketide metabolic process (GO:0030638)2.85304524
121doxorubicin metabolic process (GO:0044598)2.85304524
122daunorubicin metabolic process (GO:0044597)2.85304524
123positive regulation of lipid catabolic process (GO:0050996)2.85287355
124endocardial cushion development (GO:0003197)2.84810374
125coenzyme A metabolic process (GO:0015936)2.84242737
126protein retention in ER lumen (GO:0006621)2.84165638
127glucose 6-phosphate metabolic process (GO:0051156)2.84075048
128response to nitrosative stress (GO:0051409)2.83511319
129positive regulation of triglyceride lipase activity (GO:0061365)2.83508773
130positive regulation of lipoprotein lipase activity (GO:0051006)2.83508773
131pyrimidine nucleoside catabolic process (GO:0046135)2.83210864
132protein-lipid complex subunit organization (GO:0071825)2.82643443
133membrane budding (GO:0006900)2.82044673
134transcytosis (GO:0045056)2.81269103
135positive regulation of extracellular matrix organization (GO:1903055)2.81205995
136complement activation, classical pathway (GO:0006958)2.81023736
137fructose metabolic process (GO:0006000)2.80396086
138phosphate ion transmembrane transport (GO:0035435)2.80323154
139digestive system process (GO:0022600)2.79976606
140positive regulation of pseudopodium assembly (GO:0031274)2.79368528
141COPII vesicle coating (GO:0048208)2.79342089
142negative regulation of blood coagulation (GO:0030195)2.78248269
143negative regulation of hemostasis (GO:1900047)2.78248269
144cholesterol homeostasis (GO:0042632)2.77156749
145arginine metabolic process (GO:0006525)2.76282533
146regulation of triglyceride catabolic process (GO:0010896)2.75992331
147digestion (GO:0007586)2.75046884
148regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.74345237
149regulation of vitamin metabolic process (GO:0030656)2.74222463
150sterol homeostasis (GO:0055092)2.73818422
151glutamine family amino acid biosynthetic process (GO:0009084)2.73512288
152negative regulation of coagulation (GO:0050819)2.72694107
153bile acid biosynthetic process (GO:0006699)2.71689888
154negative regulation of fibrinolysis (GO:0051918)2.71352741
155regulation of metalloenzyme activity (GO:0048552)2.70708509
156antimicrobial humoral response (GO:0019730)2.70092737
157benzene-containing compound metabolic process (GO:0042537)2.69319672
158positive regulation of cGMP biosynthetic process (GO:0030828)2.69233589
159regulation of protein targeting to membrane (GO:0090313)2.65706522
160hydrogen peroxide catabolic process (GO:0042744)2.64794234
161cGMP-mediated signaling (GO:0019934)2.64537062
162vitamin transport (GO:0051180)2.64215951
163regulation of bile acid biosynthetic process (GO:0070857)2.64057538
164reverse cholesterol transport (GO:0043691)2.64053193
165xenobiotic catabolic process (GO:0042178)2.63609614
166regulation of cGMP metabolic process (GO:0030823)2.63148451
167cellular zinc ion homeostasis (GO:0006882)2.62909371
168kynurenine metabolic process (GO:0070189)2.62489907
169acute-phase response (GO:0006953)2.61866857
170glyoxylate metabolic process (GO:0046487)2.61540022
171maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.61003640
172mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.60371798
173cysteine metabolic process (GO:0006534)2.58244533

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.43753348
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.60772979
3RXR_22158963_ChIP-Seq_LIVER_Mouse4.24319869
4PPARA_22158963_ChIP-Seq_LIVER_Mouse3.90531065
5LXR_22158963_ChIP-Seq_LIVER_Mouse3.38270273
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.26111471
7ZNF263_19887448_ChIP-Seq_K562_Human3.08351789
8CDX2_20551321_ChIP-Seq_CACO-2_Human2.93933431
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.93048742
10* SOX2_27498859_Chip-Seq_STOMACH_Mouse2.85575759
11SOX2_20726797_ChIP-Seq_SW620_Human2.82663193
12ESR1_21235772_ChIP-Seq_MCF-7_Human2.73255339
13EGR1_23403033_ChIP-Seq_LIVER_Mouse2.71630370
14CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.68385548
15TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.63607971
16PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.57074240
17HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.56559517
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.53693761
19SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.53637056
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.47770684
21CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.35452203
22CLOCK_20551151_ChIP-Seq_293T_Human2.31777528
23FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.31361073
24GATA4_25053715_ChIP-Seq_YYC3_Human2.30349202
25CDX2_19796622_ChIP-Seq_MESCs_Mouse2.29712937
26GATA6_25053715_ChIP-Seq_YYC3_Human2.10740242
27TCF4_18268006_ChIP-ChIP_LS174T_Human2.06980124
28FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.03902517
29NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.97248680
30ESR1_20079471_ChIP-ChIP_T-47D_Human1.94341980
31STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.94223231
32GATA2_21666600_ChIP-Seq_HMVEC_Human1.88824312
33GATA1_22025678_ChIP-Seq_K562_Human1.86942224
34NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.84161992
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.79461024
36* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.78410045
37ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.78322431
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.77625717
39PPAR_26484153_Chip-Seq_NCI-H1993_Human1.69346580
40ATF3_27146783_Chip-Seq_COLON_Human1.54751414
41FOXO3_23340844_ChIP-Seq_DLD1_Human1.51015948
42EP300_21415370_ChIP-Seq_HL-1_Mouse1.49008413
43KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.42447139
44RACK7_27058665_Chip-Seq_MCF-7_Human1.42161183
45CDX2_22108803_ChIP-Seq_LS180_Human1.41797568
46RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40149504
47NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.38571515
48NRF2_20460467_ChIP-Seq_MEFs_Mouse1.38571515
49KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.36298187
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34380977
51* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.32838688
52GATA3_24758297_ChIP-Seq_MCF-7_Human1.32429230
53TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.31582626
54EGR1_19032775_ChIP-ChIP_M12_Human1.31248395
55SRY_22984422_ChIP-ChIP_TESTIS_Rat1.30205798
56CJUN_26792858_Chip-Seq_BT549_Human1.29987819
57SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.29665848
58SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.29665848
59SALL4_18804426_ChIP-ChIP_XEN_Mouse1.29537933
60SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.28866705
61BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.28736794
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.28411797
63Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.26528128
64CTNNB1_20460455_ChIP-Seq_HCT116_Human1.24805465
65NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.23762455
66BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.22977411
67TP53_18474530_ChIP-ChIP_U2OS_Human1.18528953
68ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.17741937
69RUNX1_27514584_Chip-Seq_MCF-7_Human1.15314690
70* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.13844481
71STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13056057
72TP53_16413492_ChIP-PET_HCT116_Human1.11329086
73PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.11066337
74TP63_23658742_ChIP-Seq_EP156T_Human1.09427507
75JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07852343
76CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.07532364
77KLF5_25053715_ChIP-Seq_YYC3_Human1.07222576
78TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07079206
79FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.06641392
80RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.06379943
81THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.06043495
82ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05544914
83P63_26484246_Chip-Seq_KERATINOCYTES_Human1.05017872
84JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04781120
85* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04654543
86BRD4_25478319_ChIP-Seq_HGPS_Human1.03766014
87SOX9_24532713_ChIP-Seq_HFSC_Mouse1.01808767
88GATA2_19941826_ChIP-Seq_K562_Human1.01492570
89NFIB_24661679_ChIP-Seq_LUNG_Mouse1.01035373
90ZNF274_21170338_ChIP-Seq_K562_Hela1.00362588
91* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.99637525
92NANOG_18692474_ChIP-Seq_MEFs_Mouse0.99018942
93AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.97046262
94EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.96481639
95CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.95572850
96TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.95521535
97GATA1_19941826_ChIP-Seq_K562_Human0.95458017
98FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95250593
99ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.94851938
100TBX20_22328084_ChIP-Seq_HEART_Mouse0.92162679
101TBX20_22080862_ChIP-Seq_HEART_Mouse0.92162679
102FOXA2_19822575_ChIP-Seq_HepG2_Human0.91670087
103PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91635912
104ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91038020
105* FOXA1_25552417_ChIP-Seq_VCAP_Human0.90752987
106* HNF4A_19822575_ChIP-Seq_HepG2_Human0.90704405
107IKZF1_21737484_ChIP-ChIP_HCT116_Human0.90355154
108RAD21_21589869_ChIP-Seq_MESCs_Mouse0.90054091
109* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.90050179
110RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.88858641
111IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.88503618
112SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88046559
113SMC1_22415368_ChIP-Seq_MEFs_Mouse0.87927685
114CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.87522457
115HIF1A_21447827_ChIP-Seq_MCF-7_Human0.87416721
116TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.87264311
117RXR_22108803_ChIP-Seq_LS180_Human0.87251013
118OCT4_18692474_ChIP-Seq_MEFs_Mouse0.86285918
119CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.86117548
120PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.85917307
121TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.85907551
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84701747
123ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.83926086
124CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.83822271
125AHR_22903824_ChIP-Seq_MCF-7_Human0.82997572
126SOX2_18692474_ChIP-Seq_MEFs_Mouse0.81857594
127AR_21909140_ChIP-Seq_LNCAP_Human0.81617839
128PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.80729269
129CTCF_27219007_Chip-Seq_Bcells_Human0.79115518
130UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.77306390

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle8.82580124
2MP0005360_urolithiasis4.61238759
3MP0002139_abnormal_hepatobiliary_system3.94276686
4MP0005085_abnormal_gallbladder_physiolo3.90534877
5MP0003806_abnormal_nucleotide_metabolis3.28255047
6MP0008875_abnormal_xenobiotic_pharmacok3.19536887
7MP0005377_hearing/vestibular/ear_phenot3.04675344
8MP0003878_abnormal_ear_physiology3.04675344
9MP0005365_abnormal_bile_salt2.90783982
10MP0001666_abnormal_nutrient_absorption2.90402101
11MP0003283_abnormal_digestive_organ2.59636022
12MP0004264_abnormal_extraembryonic_tissu2.57896052
13MP0004147_increased_porphyrin_level2.55483601
14MP0003252_abnormal_bile_duct2.42637512
15MP0005083_abnormal_biliary_tract2.32676799
16MP0010368_abnormal_lymphatic_system2.30817574
17MP0008438_abnormal_cutaneous_collagen2.28977487
18MP0003183_abnormal_peptide_metabolism2.20029585
19MP0002822_catalepsy2.10226705
20MP0009780_abnormal_chondrocyte_physiolo2.05311165
21MP0003705_abnormal_hypodermis_morpholog1.98914579
22MP0002876_abnormal_thyroid_physiology1.88925618
23MP0000462_abnormal_digestive_system1.88865802
24MP0005409_darkened_coat_color1.83104647
25MP0010329_abnormal_lipoprotein_level1.77479233
26MP0003950_abnormal_plasma_membrane1.75249551
27MP0003191_abnormal_cellular_cholesterol1.56149626
28MP0002736_abnormal_nociception_after1.54412970
29MP0009840_abnormal_foam_cell1.54171509
30MP0005084_abnormal_gallbladder_morpholo1.53008438
31MP0001986_abnormal_taste_sensitivity1.45456942
32MP0005332_abnormal_amino_acid1.43202162
33MP0009384_cardiac_valve_regurgitation1.42419762
34MP0001664_abnormal_digestion1.42300188
35MP0009643_abnormal_urine_homeostasis1.42299025
36MP0004043_abnormal_pH_regulation1.41772445
37MP0009697_abnormal_copulation1.38638621
38MP0010678_abnormal_skin_adnexa1.36980961
39MP0003315_abnormal_perineum_morphology1.35466958
40MP0005670_abnormal_white_adipose1.31400055
41MP0005451_abnormal_body_composition1.28048436
42MP0010030_abnormal_orbit_morphology1.26472833
43MP0010352_gastrointestinal_tract_polyps1.25639032
44MP0003656_abnormal_erythrocyte_physiolo1.25388563
45MP0003453_abnormal_keratinocyte_physiol1.22300321
46MP0000490_abnormal_crypts_of1.22244239
47MP0000477_abnormal_intestine_morphology1.22042994
48MP0006054_spinal_hemorrhage1.20473523
49MP0003300_gastrointestinal_ulcer1.17430288
50MP0003866_abnormal_defecation1.16719256
51MP0005165_increased_susceptibility_to1.16161140
52MP0002735_abnormal_chemical_nociception1.14939823
53MP0001968_abnormal_touch/_nociception1.13004496
54MP0005636_abnormal_mineral_homeostasis1.12381700
55MP0002118_abnormal_lipid_homeostasis1.11842627
56MP0002796_impaired_skin_barrier1.09918329
57MP0005381_digestive/alimentary_phenotyp1.09191973
58MP0001663_abnormal_digestive_system1.08506809
59MP0003186_abnormal_redox_activity1.08354155
60MP0003045_fibrosis1.06750766
61MP0010155_abnormal_intestine_physiology1.06397468
62MP0005167_abnormal_blood-brain_barrier1.04673076
63MP0005319_abnormal_enzyme/_coenzyme1.04387135
64MP0009053_abnormal_anal_canal1.03159690
65MP0003091_abnormal_cell_migration1.02206364
66MP0008004_abnormal_stomach_pH1.01575436
67MP0005164_abnormal_response_to1.01134594
68MP0004782_abnormal_surfactant_physiolog1.00901245
69MP0004019_abnormal_vitamin_homeostasis0.98843190
70MP0006138_congestive_heart_failure0.98248297
71MP0003868_abnormal_feces_composition0.97774007
72MP0005257_abnormal_intraocular_pressure0.96068566
73MP0000013_abnormal_adipose_tissue0.95374384
74MP0005023_abnormal_wound_healing0.94428659
75MP0005275_abnormal_skin_tensile0.93586381
76MP0002166_altered_tumor_susceptibility0.93142738
77MP0008775_abnormal_heart_ventricle0.93101124
78MP0002138_abnormal_hepatobiliary_system0.92864002
79MP0000609_abnormal_liver_physiology0.92260343
80MP0005187_abnormal_penis_morphology0.90098483
81MP0004272_abnormal_basement_membrane0.89417585
82MP0002295_abnormal_pulmonary_circulatio0.88709421
83MP0000427_abnormal_hair_cycle0.88190305
84MP0002909_abnormal_adrenal_gland0.87771809
85MP0002009_preneoplasia0.87638596
86MP0001879_abnormal_lymphatic_vessel0.87544562
87MP0000604_amyloidosis0.86804468
88MP0004858_abnormal_nervous_system0.86760571
89MP0000249_abnormal_blood_vessel0.85920594
90MP0000538_abnormal_urinary_bladder0.84722956
91MP0000681_abnormal_thyroid_gland0.81844985
92MP0000762_abnormal_tongue_morphology0.79582135
93MP0000230_abnormal_systemic_arterial0.78525409
94MP0005408_hypopigmentation0.78449015
95MP0000537_abnormal_urethra_morphology0.78306140
96MP0003195_calcinosis0.78192589
97MP0002060_abnormal_skin_morphology0.78015822
98MP0001873_stomach_inflammation0.77900520
99MP0001764_abnormal_homeostasis0.76208001
100MP0008789_abnormal_olfactory_epithelium0.76105596
101MP0002971_abnormal_brown_adipose0.75573357
102MP0003566_abnormal_cell_adhesion0.74892204
103MP0004883_abnormal_blood_vessel0.71533933
104MP0005220_abnormal_exocrine_pancreas0.71233908
105MP0005595_abnormal_vascular_smooth0.69938001
106MP0001756_abnormal_urination0.69911490
107MP0000465_gastrointestinal_hemorrhage0.69671402
108MP0002877_abnormal_melanocyte_morpholog0.68651360
109MP0000678_abnormal_parathyroid_gland0.68230098
110MP0003941_abnormal_skin_development0.66129192
111MP0002896_abnormal_bone_mineralization0.64267702
112MP0003879_abnormal_hair_cell0.63927162
113MP0000613_abnormal_salivary_gland0.63053599
114MP0004484_altered_response_of0.62733308
115MP0005584_abnormal_enzyme/coenzyme_acti0.61135262
116MP0010771_integument_phenotype0.61075692
117MP0001958_emphysema0.60609212
118MP0005666_abnormal_adipose_tissue0.60104514
119MP0002733_abnormal_thermal_nociception0.59890546
120MP0003279_aneurysm0.59560638
121MP0002098_abnormal_vibrissa_morphology0.59558248
122MP0005058_abnormal_lysosome_morphology0.59513040
123MP0009642_abnormal_blood_homeostasis0.58715838
124MP0002089_abnormal_postnatal_growth/wei0.58295767
125MP0009379_abnormal_foot_pigmentation0.56978876
126MP0000566_synostosis0.56813997
127MP0002136_abnormal_kidney_physiology0.56547353
128MP0000858_altered_metastatic_potential0.55972770
129MP0001216_abnormal_epidermal_layer0.55816922
130MP0000470_abnormal_stomach_morphology0.55778261
131MP0002132_abnormal_respiratory_system0.55670710
132MP0000767_abnormal_smooth_muscle0.55570338
133MP0005166_decreased_susceptibility_to0.54350498
134MP0009115_abnormal_fat_cell0.54030091
135MP0001270_distended_abdomen0.53918577
136MP0001346_abnormal_lacrimal_gland0.53487779
137MP0005501_abnormal_skin_physiology0.53255420
138MP0003718_maternal_effect0.53107725
139MP0002006_tumorigenesis0.52899233
140MP0001765_abnormal_ion_homeostasis0.52121364

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)4.61511328
2Flat acetabular roof (HP:0003180)4.32845448
3Abnormal tarsal ossification (HP:0008369)4.25387466
4Ileus (HP:0002595)4.23405396
5Intrahepatic cholestasis (HP:0001406)3.93175459
6Pustule (HP:0200039)3.89226128
7Abnormality of monocarboxylic acid metabolism (HP:0010996)3.86527242
8Alopecia of scalp (HP:0002293)3.68680221
9Abnormality of aromatic amino acid family metabolism (HP:0004338)3.67252453
10Cupped ribs (HP:0000887)3.67050453
11Complement deficiency (HP:0004431)3.64924333
12Abnormality of the 1st metacarpal (HP:0010009)3.62487151
13Abnormality of glutamine family amino acid metabolism (HP:0010902)3.61787603
14Abnormality of complement system (HP:0005339)3.33695614
15Abnormality of carpal bone ossification (HP:0006257)3.33397909
16Systemic lupus erythematosus (HP:0002725)3.20747415
17Hypobetalipoproteinemia (HP:0003563)3.17612681
18Pili torti (HP:0003777)3.14351403
19Arterial tortuosity (HP:0005116)3.08751175
20Hemorrhage of the eye (HP:0011885)3.05051684
21Hyperactive renin-angiotensin system (HP:0000841)3.04993413
22Deep venous thrombosis (HP:0002625)2.96506055
23Chronic diarrhea (HP:0002028)2.94450961
24Aortic dissection (HP:0002647)2.93142717
25Xanthomatosis (HP:0000991)2.87318240
26Malnutrition (HP:0004395)2.86075122
27Abnormal foot bone ossification (HP:0010675)2.85244286
28Abnormality of the vitamin B12 metabolism (HP:0004341)2.84247288
29Fat malabsorption (HP:0002630)2.82284346
30Esophageal varix (HP:0002040)2.82143085
31Glomerulonephritis (HP:0000099)2.77832361
32Abdominal distention (HP:0003270)2.70217080
33Decreased circulating renin level (HP:0003351)2.69832388
34Abnormality of vitamin metabolism (HP:0100508)2.68354524
35Conjugated hyperbilirubinemia (HP:0002908)2.67683752
36Aortic aneurysm (HP:0004942)2.66380413
37Abnormality of vitamin B metabolism (HP:0004340)2.58137346
38Curly hair (HP:0002212)2.56003197
39Villous atrophy (HP:0011473)2.55610659
40Abnormality of small intestinal villus morphology (HP:0011472)2.55610659
41Proximal tubulopathy (HP:0000114)2.54187453
42Steatorrhea (HP:0002570)2.53877227
43Hydroxyprolinuria (HP:0003080)2.53583189
44Abnormality of proline metabolism (HP:0010907)2.53583189
45Protrusio acetabuli (HP:0003179)2.46445087
46Metabolic alkalosis (HP:0200114)2.44873761
47Absent phalangeal crease (HP:0006109)2.44398881
48Abnormal ossification of hand bones (HP:0005921)2.43283558
49Nephritis (HP:0000123)2.41924002
50Hypolipoproteinemia (HP:0010981)2.41445501
51Premature rupture of membranes (HP:0001788)2.41309054
52Abnormal hand bone ossification (HP:0010660)2.40571193
53Acute encephalopathy (HP:0006846)2.40187589
54Pigmentary retinal degeneration (HP:0001146)2.40144267
55Goiter (HP:0000853)2.36754600
56Widely patent fontanelles and sutures (HP:0004492)2.36690289
57Abnormal cartilage morphology (HP:0002763)2.36439463
58Abnormality of chloride homeostasis (HP:0011422)2.34834224
59Hypoglycemic coma (HP:0001325)2.34728662
60Short phalanx of the thumb (HP:0009660)2.34366709
61Abnormality of the distal phalanx of the thumb (HP:0009617)2.34236504
62Abnormality of renin-angiotensin system (HP:0000847)2.32973424
63Abnormality of the 2nd finger (HP:0004100)2.32817792
64Progressive sensorineural hearing impairment (HP:0000408)2.32252429
65Abnormal hemoglobin (HP:0011902)2.31944830
66Glomerulosclerosis (HP:0000096)2.29200386
67Myokymia (HP:0002411)2.26804848
68Joint hemorrhage (HP:0005261)2.25498796
69Potter facies (HP:0002009)2.25195313
70Facial shape deformation (HP:0011334)2.25195313
71Short hallux (HP:0010109)2.24631667
72Vascular tortuosity (HP:0004948)2.23935790
73Cerebral edema (HP:0002181)2.22423363
74Abnormality of the proximal phalanges of the hand (HP:0009834)2.21883608
75Osteolytic defects of the hand bones (HP:0009699)2.21449122
76Osteolytic defects of the phalanges of the hand (HP:0009771)2.21449122
77Gout (HP:0001997)2.20961332
78Vascular calcification (HP:0004934)2.20315867
79Thin bony cortex (HP:0002753)2.19550932
80Confusion (HP:0001289)2.19223842
81Acute necrotizing encephalopathy (HP:0006965)2.18235052
82Wide cranial sutures (HP:0010537)2.17834191
83Mildly elevated creatine phosphokinase (HP:0008180)2.17275066
84Prolonged partial thromboplastin time (HP:0003645)2.16432867
85Myotonia (HP:0002486)2.16366932
86Sensorimotor neuropathy (HP:0007141)2.12321074
87Aplasia/Hypoplasia of the hallux (HP:0008362)2.12203702
88Cardiovascular calcification (HP:0011915)2.11589304
89Cervical subluxation (HP:0003308)2.11553598
90Fragile skin (HP:0001030)2.10455580
91Hypotension (HP:0002615)2.09982858
92Skin nodule (HP:0200036)2.08829124
93Acanthocytosis (HP:0001927)2.08807207
94Spontaneous abortion (HP:0005268)2.08777680
95Rectal prolapse (HP:0002035)2.07699751
96Renal tubular acidosis (HP:0001947)2.06652121
97Abnormality of fatty-acid metabolism (HP:0004359)2.06505886
98Menorrhagia (HP:0000132)2.05189128
99Hyperglycinuria (HP:0003108)2.04423811
100Abnormality of urine glucose concentration (HP:0011016)2.02951755
101Glycosuria (HP:0003076)2.02951755
102Abnormality of purine metabolism (HP:0004352)2.02388428
103Fragile nails (HP:0001808)2.02347697
104Palpitations (HP:0001962)2.02204653
105Neonatal short-limb short stature (HP:0008921)2.01783673
106Polycythemia (HP:0001901)2.01638427
107Hyperlipoproteinemia (HP:0010980)2.00051986
108Nephrolithiasis (HP:0000787)1.99109379
109Nausea (HP:0002018)1.98920186
110Hyperammonemia (HP:0001987)1.97853462
111Lethargy (HP:0001254)1.97374817
112Hypoalphalipoproteinemia (HP:0003233)1.96646670
113Atrophic scars (HP:0001075)1.95016561
114Hyperbilirubinemia (HP:0002904)1.94574834
115Abnormal biliary tract morphology (HP:0012440)1.93937018
116Alkalosis (HP:0001948)1.93745289
117Mitral stenosis (HP:0001718)1.93704854
118Progressive macrocephaly (HP:0004481)1.92466577
119Biliary tract neoplasm (HP:0100574)1.91320560
120Poikilocytosis (HP:0004447)1.90553403
121Aneurysm (HP:0002617)1.90057480
122Abnormality of the middle phalanges of the toes (HP:0010183)1.89778344
123Abnormal mitochondria in muscle tissue (HP:0008316)1.89620821
124Late onset (HP:0003584)1.89129029
125Wormian bones (HP:0002645)1.88658565
126Onycholysis (HP:0001806)1.88398743
127Exocrine pancreatic insufficiency (HP:0001738)1.88263680
128Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.86424498
129Gastrointestinal dysmotility (HP:0002579)1.85455655
130Irregular epiphyses (HP:0010582)1.85252114
131Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.85081058
132Chondrocalcinosis (HP:0000934)1.84189849
133Abnormal finger flexion creases (HP:0006143)1.83876510
134Epidermoid cyst (HP:0200040)1.83507094
135Abnormality of aspartate family amino acid metabolism (HP:0010899)1.82603422
136Abnormal glucose tolerance (HP:0001952)1.80694188
137Hypophosphatemia (HP:0002148)1.80338271
138Abnormality of Sharpey fibers (HP:0100685)1.80124768
139Progressive hearing impairment (HP:0001730)1.80120971
140Cholecystitis (HP:0001082)1.80111445
141Abnormal gallbladder physiology (HP:0012438)1.80111445
142Popliteal pterygium (HP:0009756)1.78802942
143Abnormality of the intrinsic pathway (HP:0010989)1.78499482
144Vertebral hypoplasia (HP:0008417)1.77107464
145Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.77107464
146Congenital sensorineural hearing impairment (HP:0008527)1.76481611
147Focal segmental glomerulosclerosis (HP:0000097)1.76332524
148Follicular hyperkeratosis (HP:0007502)1.75567787
149Rickets (HP:0002748)1.75037906
150Abnormality of sulfur amino acid metabolism (HP:0004339)1.74965958
151Growth hormone excess (HP:0000845)1.74939568
152Abnormality of dicarboxylic acid metabolism (HP:0010995)1.74325411
153Dicarboxylic aciduria (HP:0003215)1.74325411
154Megaloblastic anemia (HP:0001889)1.74147820
155Abnormality of the acetabulum (HP:0003170)1.74015857
156Hyperaldosteronism (HP:0000859)1.73944149
157Abnormality of the common coagulation pathway (HP:0010990)1.73300347

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PIK3CA6.37888280
2FRK6.09017648
3MST1R3.83296691
4ACVR1B3.74117248
5LMTK23.64148051
6MAP3K23.17381754
7MAP2K23.09090692
8RIPK13.08091213
9TESK12.78136622
10GRK52.51714530
11LIMK12.30004975
12KSR22.14963898
13MST42.07081869
14PRKG22.06423555
15MYLK2.02789022
16LATS11.85558983
17MET1.78317468
18EPHB21.77367636
19TGFBR21.69377558
20MAP2K11.50851761
21BCKDK1.50193175
22EPHA21.46359039
23MAP3K121.43431324
24TIE11.36153712
25PDK21.28272495
26LATS21.27700585
27RIPK41.24655434
28DDR21.21093956
29PAK41.17284429
30CAMK2D1.16442585
31PIM21.15386096
32FER1.15206140
33NME21.14803645
34NME11.13131037
35TRPM71.11328899
36RPS6KB21.05790304
37PTK21.05143678
38NTRK11.01425983
39WNK40.98630355
40ARAF0.98167431
41PRKCI0.92835551
42MAP3K30.91690143
43EPHB10.85997649
44EPHA30.85312275
45PDGFRB0.81922523
46TAOK10.81226914
47FGFR20.79941296
48NLK0.78633264
49STK30.76982600
50MAP3K140.76854348
51JAK10.76029944
52MARK30.72442867
53YES10.70248996
54TESK20.69411863
55MAP3K90.69087890
56OXSR10.67229740
57MAP3K10.67141201
58SIK10.66619823
59GRK10.66551636
60MAPKAPK50.65277087
61RET0.63054626
62ERBB30.62971512
63LRRK20.62774746
64ICK0.62723374
65EIF2AK30.62180868
66EIF2AK10.61824514
67NEK10.60987309
68IRAK30.60252219
69STK38L0.59066087
70PKN20.58087990
71STK100.57726924
72FGFR40.57699206
73TYK20.57090800
74MAP3K70.55830689
75DAPK20.55346606
76NEK90.54657253
77MAP3K110.54282013
78BRSK20.53908644
79ROCK10.53474639
80KDR0.51373935
81CAMK2G0.49787419
82PAK30.49750371
83BMPR20.49155025
84SGK4940.48344339
85SGK2230.48344339
86DAPK30.47931387
87BMPR1B0.47696818
88PBK0.47404911
89GRK70.47307966
90BMX0.47264314
91PIK3CG0.47184771
92ERN10.46706445
93CDC42BPA0.46484958
94MUSK0.45237951
95PDGFRA0.44036561
96FGFR10.43907482
97SGK20.42753880
98MATK0.42017350
99MAPKAPK30.41799942
100ABL20.41605881
101AKT30.41430385
102DMPK0.41085222
103STK390.40050509
104CDK60.39676372
105INSRR0.39573945
106MELK0.39289542
107MAP3K80.38219435
108PAK20.38156851
109SGK30.37747358
110BCR0.37737757
111STK240.36714512
112MAP3K100.36112629
113SCYL20.35720810
114ZAK0.35004937
115CAMK2B0.34835803
116PTK60.33656440
117DYRK1B0.33509949
118PRPF4B0.33154149
119WNK10.32408915
120STK380.32267749
121ADRBK10.32179448
122PRKAA20.32179090
123MAPKAPK20.31787249
124PRKCA0.30821172
125IGF1R0.30579077
126EPHA40.29597579
127PDK10.29126915
128GRK60.29120719
129SRC0.28910941
130BRAF0.28220215
131MAPK110.27924223
132PRKACG0.27128651
133FLT30.26881811
134ERBB40.26802102
135AURKB0.24352800
136TTK0.22881694
137CDK140.22224116
138PDPK10.21857543
139ERBB20.21399924
140WNK30.20829009
141FGFR30.20616442

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009205.33231553
2Cyanoamino acid metabolism_Homo sapiens_hsa004603.47330282
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.95454569
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.94828326
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.61566886
6Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.57169737
7Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.52159402
8Fat digestion and absorption_Homo sapiens_hsa049752.44567531
9Primary bile acid biosynthesis_Homo sapiens_hsa001202.41426136
10Bile secretion_Homo sapiens_hsa049762.32922371
11Sulfur relay system_Homo sapiens_hsa041222.21059566
12Pentose and glucuronate interconversions_Homo sapiens_hsa000402.20123619
13Mineral absorption_Homo sapiens_hsa049782.17872540
14Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.14404569
15Chemical carcinogenesis_Homo sapiens_hsa052042.03875325
16Steroid hormone biosynthesis_Homo sapiens_hsa001401.89491419
17Tryptophan metabolism_Homo sapiens_hsa003801.84607992
18Histidine metabolism_Homo sapiens_hsa003401.81798791
19Oxidative phosphorylation_Homo sapiens_hsa001901.77243052
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.69826953
21Butanoate metabolism_Homo sapiens_hsa006501.68044398
22Starch and sucrose metabolism_Homo sapiens_hsa005001.67347788
23Fatty acid degradation_Homo sapiens_hsa000711.57516106
24Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46970007
25Parkinsons disease_Homo sapiens_hsa050121.45583630
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43268994
27Linoleic acid metabolism_Homo sapiens_hsa005911.38801369
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.34993075
29Arginine biosynthesis_Homo sapiens_hsa002201.26640120
30Fructose and mannose metabolism_Homo sapiens_hsa000511.26584280
31Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.26577191
32Peroxisome_Homo sapiens_hsa041461.25651003
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.23210159
34Glutathione metabolism_Homo sapiens_hsa004801.23123793
35Folate biosynthesis_Homo sapiens_hsa007901.20581012
36Phenylalanine metabolism_Homo sapiens_hsa003601.20380615
37Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.19692084
38Renin-angiotensin system_Homo sapiens_hsa046141.19084503
39PPAR signaling pathway_Homo sapiens_hsa033201.16781140
40Alzheimers disease_Homo sapiens_hsa050101.16185106
41Caffeine metabolism_Homo sapiens_hsa002321.16180998
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.14907485
43Galactose metabolism_Homo sapiens_hsa000521.13091339
44Complement and coagulation cascades_Homo sapiens_hsa046101.10568289
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.08606765
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.05683901
47Protein digestion and absorption_Homo sapiens_hsa049741.02296459
48Pyruvate metabolism_Homo sapiens_hsa006201.01651017
49Retinol metabolism_Homo sapiens_hsa008300.97614982
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.97105623
51Glycerolipid metabolism_Homo sapiens_hsa005610.94601159
52Propanoate metabolism_Homo sapiens_hsa006400.94576075
53Tyrosine metabolism_Homo sapiens_hsa003500.92316190
54Vitamin digestion and absorption_Homo sapiens_hsa049770.91731239
55Other glycan degradation_Homo sapiens_hsa005110.90180817
56Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.86383194
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.86016418
58Pancreatic secretion_Homo sapiens_hsa049720.84645865
59Tight junction_Homo sapiens_hsa045300.84227978
60beta-Alanine metabolism_Homo sapiens_hsa004100.81598631
61Fatty acid metabolism_Homo sapiens_hsa012120.79154190
62Bladder cancer_Homo sapiens_hsa052190.79022722
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.78105482
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74697784
65Huntingtons disease_Homo sapiens_hsa050160.74672999
66Arginine and proline metabolism_Homo sapiens_hsa003300.73943692
67Fatty acid biosynthesis_Homo sapiens_hsa000610.72828363
68Thyroid hormone synthesis_Homo sapiens_hsa049180.72803899
69Cardiac muscle contraction_Homo sapiens_hsa042600.70432853
70Selenocompound metabolism_Homo sapiens_hsa004500.63986906
71Arachidonic acid metabolism_Homo sapiens_hsa005900.63626349
72Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60279717
73Carbon metabolism_Homo sapiens_hsa012000.60028971
74Steroid biosynthesis_Homo sapiens_hsa001000.58192626
75Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57201705
76Thyroid cancer_Homo sapiens_hsa052160.55926315
77ABC transporters_Homo sapiens_hsa020100.52853219
78Metabolic pathways_Homo sapiens_hsa011000.52739627
79Focal adhesion_Homo sapiens_hsa045100.52125578
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.51919499
81Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.47585204
82Insulin resistance_Homo sapiens_hsa049310.46033402
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45522086
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45225143
85Nitrogen metabolism_Homo sapiens_hsa009100.44995867
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44214471
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.43815518
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40595959
89Pertussis_Homo sapiens_hsa051330.40316565
90Prion diseases_Homo sapiens_hsa050200.39865831
91Glycerophospholipid metabolism_Homo sapiens_hsa005640.39813026
92Salmonella infection_Homo sapiens_hsa051320.38692725
93ECM-receptor interaction_Homo sapiens_hsa045120.38106062
942-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.37837935
95Renin secretion_Homo sapiens_hsa049240.35489019
96Biosynthesis of amino acids_Homo sapiens_hsa012300.31957631
97Ether lipid metabolism_Homo sapiens_hsa005650.31579078
98Fatty acid elongation_Homo sapiens_hsa000620.30419411
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.29605352
100Ovarian steroidogenesis_Homo sapiens_hsa049130.29412159
101N-Glycan biosynthesis_Homo sapiens_hsa005100.27536027
102Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.26115533
103Staphylococcus aureus infection_Homo sapiens_hsa051500.25950836
104Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25877271
105Vascular smooth muscle contraction_Homo sapiens_hsa042700.25104989
106Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24336886
107Insulin signaling pathway_Homo sapiens_hsa049100.23304968
108Adherens junction_Homo sapiens_hsa045200.23010064
109Proteoglycans in cancer_Homo sapiens_hsa052050.22954078
110TGF-beta signaling pathway_Homo sapiens_hsa043500.21257037
111Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.21060305
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20393621
113Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.19190628
114Amoebiasis_Homo sapiens_hsa051460.18650884
115Hepatitis C_Homo sapiens_hsa051600.17168411
116Small cell lung cancer_Homo sapiens_hsa052220.17090498
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.16194295
118Sphingolipid metabolism_Homo sapiens_hsa006000.15485699
119Pentose phosphate pathway_Homo sapiens_hsa000300.13840804
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.11326084
121Adipocytokine signaling pathway_Homo sapiens_hsa049200.10872596
122Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.09986835

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