CCDC71

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)5.08778998
2DNA unwinding involved in DNA replication (GO:0006268)4.46314872
3viral transcription (GO:0019083)4.41751820
4DNA deamination (GO:0045006)4.35317948
5translational termination (GO:0006415)4.24851530
6peptidyl-arginine omega-N-methylation (GO:0035247)4.21299025
7ribosomal small subunit assembly (GO:0000028)4.16059985
8translational elongation (GO:0006414)4.05664400
9negative regulation of erythrocyte differentiation (GO:0045647)4.05624798
10NIK/NF-kappaB signaling (GO:0038061)3.97362406
11formation of translation preinitiation complex (GO:0001731)3.86995836
12protein localization to endosome (GO:0036010)3.83808567
13translational initiation (GO:0006413)3.74637904
14pentose-phosphate shunt (GO:0006098)3.72595538
15nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.64016844
16regulation of translational fidelity (GO:0006450)3.58564525
17positive regulation by symbiont of host defense response (GO:0052509)3.57295322
18modulation by symbiont of host defense response (GO:0052031)3.57295322
19modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.57295322
20modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.57295322
21positive regulation by organism of defense response of other organism involved in symbiotic interact3.57295322
22modulation by symbiont of host immune response (GO:0052553)3.57295322
23IMP biosynthetic process (GO:0006188)3.55626061
24maturation of SSU-rRNA (GO:0030490)3.54565499
25negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.54067139
26peptidyl-arginine N-methylation (GO:0035246)3.53905804
27peptidyl-arginine methylation (GO:0018216)3.53905804
28antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.48873401
29antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.48873401
30folic acid metabolic process (GO:0046655)3.46337375
31regulation of protein heterodimerization activity (GO:0043497)3.41041438
32response to peptidoglycan (GO:0032494)3.39446534
33viral life cycle (GO:0019058)3.39210689
34cellular protein complex disassembly (GO:0043624)3.36569600
35nucleobase biosynthetic process (GO:0046112)3.35323890
36translesion synthesis (GO:0019985)3.34214705
37mitotic nuclear envelope disassembly (GO:0007077)3.33371668
38pre-miRNA processing (GO:0031054)3.32982118
39mitotic G1 DNA damage checkpoint (GO:0031571)3.32248026
40maternal placenta development (GO:0001893)3.31887756
41protein localization to kinetochore (GO:0034501)3.30719732
42purine nucleobase biosynthetic process (GO:0009113)3.30639501
43negative regulation of RNA splicing (GO:0033119)3.29617653
44SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.28016329
45protein complex disassembly (GO:0043241)3.24659273
46histone arginine methylation (GO:0034969)3.21548963
47ribosomal small subunit biogenesis (GO:0042274)3.21366416
48regulation of translational termination (GO:0006449)3.18947360
49pinocytosis (GO:0006907)3.18093706
50protein targeting to ER (GO:0045047)3.15491102
51DNA strand elongation involved in DNA replication (GO:0006271)3.13631861
52NADPH regeneration (GO:0006740)3.11664561
53cotranslational protein targeting to membrane (GO:0006613)3.11487014
54membrane disassembly (GO:0030397)3.09682609
55nuclear envelope disassembly (GO:0051081)3.09682609
56mannose metabolic process (GO:0006013)3.08820944
57glycine metabolic process (GO:0006544)3.08578297
58IMP metabolic process (GO:0046040)3.07121269
59macromolecular complex disassembly (GO:0032984)3.02639296
60barbed-end actin filament capping (GO:0051016)3.02354390
61modulation by symbiont of host cellular process (GO:0044068)2.99167365
62regulation of type I interferon-mediated signaling pathway (GO:0060338)2.98468401
63response to laminar fluid shear stress (GO:0034616)2.97570294
64pteridine-containing compound biosynthetic process (GO:0042559)2.97450991
65establishment of protein localization to endoplasmic reticulum (GO:0072599)2.97055456
66apoptotic process involved in morphogenesis (GO:0060561)2.96500802
67regulation of early endosome to late endosome transport (GO:2000641)2.95510425
68Arp2/3 complex-mediated actin nucleation (GO:0034314)2.94626424
69protein localization to endoplasmic reticulum (GO:0070972)2.93463853
70DNA strand elongation (GO:0022616)2.92283326
71positive regulation of Cdc42 GTPase activity (GO:0043089)2.92127021
72T cell apoptotic process (GO:0070231)2.91899286
73mitotic chromosome condensation (GO:0007076)2.91846526
74positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.91539729
75negative regulation of cell killing (GO:0031342)2.90314709
76negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.90314709
77galactose catabolic process (GO:0019388)2.89103767
78protein localization to chromosome, centromeric region (GO:0071459)2.89043516
79macrophage activation involved in immune response (GO:0002281)2.88337127
80DNA replication initiation (GO:0006270)2.88067951
81stress fiber assembly (GO:0043149)2.86109328
82postreplication repair (GO:0006301)2.85966937
83regulation of gamma-delta T cell differentiation (GO:0045586)2.85763500
84glucose catabolic process (GO:0006007)2.83961025
85ribosome biogenesis (GO:0042254)2.81522023
86lipopolysaccharide-mediated signaling pathway (GO:0031663)2.81046370
87endothelial tube morphogenesis (GO:0061154)2.80280509
88morphogenesis of an endothelium (GO:0003159)2.80280509
89nuclear-transcribed mRNA catabolic process (GO:0000956)2.80148166
90antigen processing and presentation of endogenous antigen (GO:0019883)2.79167768
91ncRNA 3-end processing (GO:0043628)2.79072860
92negative regulation of cell size (GO:0045792)2.78213992
93DNA replication-dependent nucleosome assembly (GO:0006335)2.77389812
94DNA replication-dependent nucleosome organization (GO:0034723)2.77389812
95response to muramyl dipeptide (GO:0032495)2.77164362
96ribonucleoprotein complex biogenesis (GO:0022613)2.75506825
97spliceosomal snRNP assembly (GO:0000387)2.74507167
98peptidyl-lysine dimethylation (GO:0018027)2.73548496
99regulation of mammary gland epithelial cell proliferation (GO:0033599)2.73498800
100nuclear envelope organization (GO:0006998)2.72109873
101regulation of interferon-beta biosynthetic process (GO:0045357)2.71755883
102embryonic process involved in female pregnancy (GO:0060136)2.71623028
103positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.70692713
104epithelial cell differentiation involved in prostate gland development (GO:0060742)2.70167595
105negative regulation of viral release from host cell (GO:1902187)2.68703749
106negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.68679913
1073-UTR-mediated mRNA stabilization (GO:0070935)2.65827979
108trophectodermal cell differentiation (GO:0001829)2.65247344
109ribosomal large subunit biogenesis (GO:0042273)2.65205558
110mitotic sister chromatid segregation (GO:0000070)2.64876943
111negative regulation of interleukin-12 production (GO:0032695)2.64827510
112detection of other organism (GO:0098543)2.64413047
113positive regulation of gamma-delta T cell activation (GO:0046645)2.64019862
114mRNA catabolic process (GO:0006402)2.62931147
115negative regulation of mRNA processing (GO:0050686)2.62407492
116regulation of necroptotic process (GO:0060544)2.62138258
117regulation of posttranscriptional gene silencing (GO:0060147)2.61957212
118regulation of gene silencing by miRNA (GO:0060964)2.61957212
119regulation of gene silencing by RNA (GO:0060966)2.61957212
120positive regulation of B cell differentiation (GO:0045579)2.61843929
121RNA catabolic process (GO:0006401)2.61433649
122regulation of spindle organization (GO:0090224)2.60016201
123RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.59452306
124mRNA splicing, via spliceosome (GO:0000398)2.59452306
125mitotic G1/S transition checkpoint (GO:0044819)2.58398256
126adherens junction assembly (GO:0034333)2.57694510
127detection of bacterium (GO:0016045)2.57135589
128antigen processing and presentation via MHC class Ib (GO:0002475)2.56882214
129telomere maintenance via semi-conservative replication (GO:0032201)2.56673219
130sister chromatid segregation (GO:0000819)2.56561181
131DNA duplex unwinding (GO:0032508)2.56422549
132positive regulation of protein deacetylation (GO:0090312)2.56312907
133cell-substrate adherens junction assembly (GO:0007045)2.56117697
134focal adhesion assembly (GO:0048041)2.56117697
135regulation of mitotic spindle organization (GO:0060236)2.55399713
136immunoglobulin mediated immune response (GO:0016064)2.55019008
137tetrahydrofolate metabolic process (GO:0046653)2.54875004
138modulation by virus of host process (GO:0019054)2.54487522
139regulation of RNA export from nucleus (GO:0046831)2.53845611
140COPI coating of Golgi vesicle (GO:0048205)2.53680438
141Golgi transport vesicle coating (GO:0048200)2.53680438
142negative regulation of necroptotic process (GO:0060546)2.48489914
143cellular response to virus (GO:0098586)2.47902351
144myeloid dendritic cell differentiation (GO:0043011)2.44669851
145regulation of NFAT protein import into nucleus (GO:0051532)2.44655656
146type I interferon signaling pathway (GO:0060337)2.44207832
147cellular response to type I interferon (GO:0071357)2.44207832
148antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.42761560
149response to type I interferon (GO:0034340)2.41433668
150germinal center formation (GO:0002467)2.39753137
151positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.38361996
152activation of MAPKKK activity (GO:0000185)2.36467805
153activation of Rac GTPase activity (GO:0032863)2.36331219
154basement membrane organization (GO:0071711)2.34822538
155cell-substrate junction assembly (GO:0007044)2.34298734
156endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.32439614
157detection of external biotic stimulus (GO:0098581)2.32140889
158positive thymic T cell selection (GO:0045059)2.31903088
159proline biosynthetic process (GO:0006561)2.30953934
160response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.30687971
161response to host (GO:0075136)2.30687971
162response to host defenses (GO:0052200)2.30687971
163thymic T cell selection (GO:0045061)2.30381635
164retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.28755825
165spliceosomal tri-snRNP complex assembly (GO:0000244)2.27661816
166regulation of leukocyte degranulation (GO:0043300)2.26750445
167response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.26691476
168response to host immune response (GO:0052572)2.26691476
169detection of molecule of bacterial origin (GO:0032490)2.26409640
170neutrophil activation involved in immune response (GO:0002283)2.26093794
171B cell receptor signaling pathway (GO:0050853)2.25454271
172regulation of T-helper 2 cell differentiation (GO:0045628)2.24766008
173intracellular estrogen receptor signaling pathway (GO:0030520)2.23591520
174positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.22597827
175regulation of gamma-delta T cell activation (GO:0046643)2.22584719
176regulation of necrotic cell death (GO:0010939)2.22109560
177regulation of defense response to virus by virus (GO:0050690)2.22096150
178regulation of macrophage cytokine production (GO:0010935)2.21670156
179negative regulation of toll-like receptor signaling pathway (GO:0034122)2.20698302
180low-density lipoprotein particle clearance (GO:0034383)2.20512597
181positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.20470653
182regulation of apoptotic process involved in morphogenesis (GO:1902337)2.20421948
183regulation of glucose import in response to insulin stimulus (GO:2001273)2.20084881
184leukocyte aggregation (GO:0070486)2.20014956
185regulation of superoxide anion generation (GO:0032928)2.19436855
186regulation of extracellular matrix disassembly (GO:0010715)2.16224316
187regulation of vitamin D biosynthetic process (GO:0060556)2.15980184

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.32141686
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.99924704
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.18480451
4MYC_22102868_ChIP-Seq_BL_Human3.11627222
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.05257080
6TP63_17297297_ChIP-ChIP_HaCaT_Human2.94861915
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42303274
8VDR_21846776_ChIP-Seq_THP-1_Human2.24700131
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.17540661
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.17233003
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.16447830
12XRN2_22483619_ChIP-Seq_HELA_Human2.13013677
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.02520765
14MYC_19030024_ChIP-ChIP_MESCs_Mouse1.97958934
15TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.96322857
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.90498719
17ETS1_20019798_ChIP-Seq_JURKAT_Human1.87068149
18THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.79687303
19NELFA_20434984_ChIP-Seq_ESCs_Mouse1.76273754
20CIITA_25753668_ChIP-Seq_RAJI_Human1.76239929
21TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.76172161
22E2F4_17652178_ChIP-ChIP_JURKAT_Human1.73581640
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.71207944
24ZNF263_19887448_ChIP-Seq_K562_Human1.71043893
25JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70679379
26MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.68606378
27BRD4_27068464_Chip-Seq_AML-cells_Mouse1.68545819
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.66565730
29NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64244321
30ELK3_25401928_ChIP-Seq_HUVEC_Human1.60076948
31CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.58955919
32SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.58088689
33CREB1_15753290_ChIP-ChIP_HEK293T_Human1.57906332
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56855110
35PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.56706571
36* GABP_19822575_ChIP-Seq_HepG2_Human1.56489771
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.54796698
38POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.54484200
39DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.53860472
40STAT6_21828071_ChIP-Seq_BEAS2B_Human1.53442427
41ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52849302
42TCF7_22412390_ChIP-Seq_EML_Mouse1.52795820
43SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.52082409
44UTX_26944678_Chip-Seq_JUKART_Human1.50576471
45LXR_22292898_ChIP-Seq_THP-1_Human1.50412874
46MYB_21317192_ChIP-Seq_ERMYB_Mouse1.48156943
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.47389458
48KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.46147673
49KLF4_18555785_ChIP-Seq_MESCs_Mouse1.43759820
50RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.43091388
51* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.42478167
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.41708018
53MAF_26560356_Chip-Seq_TH1_Human1.41657199
54KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41540323
55RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.40801859
56POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.40408894
57KDM2B_26808549_Chip-Seq_DND41_Human1.39644466
58TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.36476715
59ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36192570
60KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34630876
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34418363
62KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.34248070
63GABP_17652178_ChIP-ChIP_JURKAT_Human1.33682512
64KDM2B_26808549_Chip-Seq_JURKAT_Human1.33534752
65EST1_17652178_ChIP-ChIP_JURKAT_Human1.32994423
66TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.32924743
67P300_27058665_Chip-Seq_ZR-75-30cells_Human1.32299462
68CTCF_27219007_Chip-Seq_ERYTHROID_Human1.32005605
69KDM2B_26808549_Chip-Seq_K562_Human1.31833060
70VDR_23849224_ChIP-Seq_CD4+_Human1.30606780
71NCOR1_26117541_ChIP-Seq_K562_Human1.30124294
72KDM5A_27292631_Chip-Seq_BREAST_Human1.29592842
73FOXP3_21729870_ChIP-Seq_TREG_Human1.29074073
74MYCN_18555785_ChIP-Seq_MESCs_Mouse1.27909326
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.27768950
76UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.26121383
77E2F1_21310950_ChIP-Seq_MCF-7_Human1.26063813
78DCP1A_22483619_ChIP-Seq_HELA_Human1.25739387
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.24610744
80SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23471768
81SA1_27219007_Chip-Seq_ERYTHROID_Human1.23418998
82* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.23179770
83SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22448409
84THAP11_20581084_ChIP-Seq_MESCs_Mouse1.21934191
85BP1_19119308_ChIP-ChIP_Hs578T_Human1.21246356
86TTF2_22483619_ChIP-Seq_HELA_Human1.20700829
87KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20120567
88* SPI1_23547873_ChIP-Seq_NB4_Human1.19502317
89PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.19471273
90E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.18722869
91NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.16832730
92ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16798685
93KDM2B_26808549_Chip-Seq_SUP-B15_Human1.16780090
94ZFP281_18757296_ChIP-ChIP_E14_Mouse1.16230139
95AR_21909140_ChIP-Seq_LNCAP_Human1.16050652
96RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15315356
97IRF8_21731497_ChIP-ChIP_J774_Mouse1.14457010
98SRY_22984422_ChIP-ChIP_TESTIS_Rat1.13463170
99TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13203581
100MAF_26560356_Chip-Seq_TH2_Human1.12771192
101CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.11306441
102IRF8_27001747_Chip-Seq_BMDM_Mouse1.11207534
103YY1_21170310_ChIP-Seq_MESCs_Mouse1.10305416
104ATF3_27146783_Chip-Seq_COLON_Human1.10141733
105SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.09721949
106P68_20966046_ChIP-Seq_HELA_Human1.09582910
107SPI1_23127762_ChIP-Seq_K562_Human1.09223035
108EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.08812468
109VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.07241212
110ELF1_20517297_ChIP-Seq_JURKAT_Human1.06803647
111RACK7_27058665_Chip-Seq_MCF-7_Human1.06150316
112CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05456180
113EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05287079
114NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.04943055
115ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.04734738
116ESR1_15608294_ChIP-ChIP_MCF-7_Human1.04517420
117MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.04420620
118TFEB_21752829_ChIP-Seq_HELA_Human1.04184830
119TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03859003
120GATA1_19941827_ChIP-Seq_MEL_Mouse1.03486811
121VDR_24763502_ChIP-Seq_THP-1_Human1.03288880
122UBF1/2_26484160_Chip-Seq_HMECs_Human1.03100392
123PU.1_20513432_ChIP-Seq_Bcells_Mouse1.02928913
124TP53_22127205_ChIP-Seq_IMR90_Human1.02536810
125MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.01244751
126TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.00588420
127GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99934749
128* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99808834
129BCOR_27268052_Chip-Seq_Bcells_Human0.99731636
130ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99664706
131ESR2_21235772_ChIP-Seq_MCF-7_Human0.99600558
132CREB1_26743006_Chip-Seq_LNCaP_Human0.99445298
133OCT4_18692474_ChIP-Seq_MEFs_Mouse0.99323578
134GATA1_22383799_ChIP-Seq_G1ME_Mouse0.98126415
135RUNX1_22412390_ChIP-Seq_EML_Mouse0.97810561
136KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.97397262
137YY1_22570637_ChIP-Seq_MALME-3M_Human0.97366396
138FOXP1_21924763_ChIP-Seq_HESCs_Human0.97014813
139BCL6_27268052_Chip-Seq_Bcells_Human0.96162970
140CLOCK_20551151_ChIP-Seq_293T_Human0.95716813
141NANOG_21062744_ChIP-ChIP_HESCs_Human0.95014971
142HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.94734235
143TET1_21451524_ChIP-Seq_MESCs_Mouse0.94590247

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition3.29594219
2MP0003693_abnormal_embryo_hatching3.25865975
3MP0004957_abnormal_blastocyst_morpholog3.13379242
4MP0010352_gastrointestinal_tract_polyps3.02147718
5MP0003705_abnormal_hypodermis_morpholog2.83204533
6MP0003111_abnormal_nucleus_morphology2.78648037
7MP0003436_decreased_susceptibility_to2.72557696
8MP0003077_abnormal_cell_cycle2.56197538
9MP0005058_abnormal_lysosome_morphology2.53514282
10MP0009840_abnormal_foam_cell2.32466437
11MP0008438_abnormal_cutaneous_collagen2.26968468
12MP0010094_abnormal_chromosome_stability2.20933551
13MP0010234_abnormal_vibrissa_follicle2.10301592
14MP0002396_abnormal_hematopoietic_system2.09416496
15MP0002877_abnormal_melanocyte_morpholog2.07780817
16MP0001730_embryonic_growth_arrest1.92440479
17MP0001835_abnormal_antigen_presentation1.89787927
18MP0008007_abnormal_cellular_replicative1.85955552
19MP0008260_abnormal_autophagy1.85760499
20MP0004808_abnormal_hematopoietic_stem1.85112688
21MP0003566_abnormal_cell_adhesion1.80002539
22MP0005076_abnormal_cell_differentiation1.76951195
23MP0003453_abnormal_keratinocyte_physiol1.75261807
24MP0000350_abnormal_cell_proliferation1.72445586
25MP0003123_paternal_imprinting1.70513573
26MP0005000_abnormal_immune_tolerance1.69121438
27MP0003763_abnormal_thymus_physiology1.68782745
28MP0002419_abnormal_innate_immunity1.65026667
29MP0003091_abnormal_cell_migration1.64805915
30MP0005387_immune_system_phenotype1.62376969
31MP0001790_abnormal_immune_system1.62376969
32MP0005257_abnormal_intraocular_pressure1.61269986
33MP0005025_abnormal_response_to1.59699395
34MP0004858_abnormal_nervous_system1.59508150
35MP0009278_abnormal_bone_marrow1.56965909
36MP0009333_abnormal_splenocyte_physiolog1.56448326
37MP0002653_abnormal_ependyma_morphology1.53987220
38MP0002080_prenatal_lethality1.53818584
39MP0002019_abnormal_tumor_incidence1.50835162
40MP0003172_abnormal_lysosome_physiology1.50408242
41MP0006054_spinal_hemorrhage1.49902570
42MP0001545_abnormal_hematopoietic_system1.49761083
43MP0005397_hematopoietic_system_phenotyp1.49761083
44MP0000703_abnormal_thymus_morphology1.48530729
45MP0004510_myositis1.46888321
46MP0002398_abnormal_bone_marrow1.45221205
47MP0001849_ear_inflammation1.44928670
48MP0001697_abnormal_embryo_size1.44720457
49MP0000490_abnormal_crypts_of1.44195950
50MP0009785_altered_susceptibility_to1.41716765
51MP0010307_abnormal_tumor_latency1.40789618
52MP0003303_peritoneal_inflammation1.40617040
53MP0001672_abnormal_embryogenesis/_devel1.40189688
54MP0005380_embryogenesis_phenotype1.40189688
55MP0003300_gastrointestinal_ulcer1.38735370
56MP0000685_abnormal_immune_system1.37241771
57MP0002722_abnormal_immune_system1.37210022
58MP0005023_abnormal_wound_healing1.36992808
59MP0002723_abnormal_immune_serum1.35929493
60MP0001533_abnormal_skeleton_physiology1.35416496
61MP0002088_abnormal_embryonic_growth/wei1.35345692
62MP0003984_embryonic_growth_retardation1.35259805
63MP0002148_abnormal_hypersensitivity_rea1.33620319
64MP0003279_aneurysm1.32297420
65MP0004197_abnormal_fetal_growth/weight/1.32056020
66MP0002086_abnormal_extraembryonic_tissu1.32035211
67MP0008932_abnormal_embryonic_tissue1.28434379
68MP0000358_abnormal_cell_content/1.27747251
69MP0002084_abnormal_developmental_patter1.27192853
70MP0000689_abnormal_spleen_morphology1.26027679
71MP0005623_abnormal_meninges_morphology1.25965529
72MP0002085_abnormal_embryonic_tissue1.25124243
73MP0003191_abnormal_cellular_cholesterol1.23816945
74MP0000858_altered_metastatic_potential1.23093103
75MP0010030_abnormal_orbit_morphology1.22194470
76MP0002254_reproductive_system_inflammat1.20750696
77MP0002998_abnormal_bone_remodeling1.19848106
78MP0006082_CNS_inflammation1.19280196
79MP0003724_increased_susceptibility_to1.19012756
80MP0002405_respiratory_system_inflammati1.18860811
81MP0003806_abnormal_nucleotide_metabolis1.18342162
82MP0000313_abnormal_cell_death1.17993364
83MP0005671_abnormal_response_to1.17262583
84MP0000537_abnormal_urethra_morphology1.17022892
85MP0000465_gastrointestinal_hemorrhage1.15621481
86MP0002429_abnormal_blood_cell1.11002996
87MP0005501_abnormal_skin_physiology1.10232309
88MP0008770_decreased_survivor_rate1.10177387
89MP0003075_altered_response_to1.05931751
90MP0000733_abnormal_muscle_development1.04730355
91MP0009053_abnormal_anal_canal1.02115342
92MP0004272_abnormal_basement_membrane1.01178277
93MP0008961_abnormal_basal_metabolism1.00958134
94MP0003115_abnormal_respiratory_system1.00468895
95MP0000477_abnormal_intestine_morphology1.00452148
96MP0003828_pulmonary_edema1.00379354
97MP0003119_abnormal_digestive_system0.99913535
98MP0001845_abnormal_inflammatory_respons0.99663282
99MP0005464_abnormal_platelet_physiology0.98918929
100MP0000604_amyloidosis0.98582767
101MP0009672_abnormal_birth_weight0.98421925
102MP0004947_skin_inflammation0.98055446
103MP0005666_abnormal_adipose_tissue0.97161784
104MP0000767_abnormal_smooth_muscle0.96745485
105MP0002269_muscular_atrophy0.96721328
106MP0003221_abnormal_cardiomyocyte_apopto0.96649185
107MP0002796_impaired_skin_barrier0.96392226
108MP0000716_abnormal_immune_system0.95853427
109MP0008058_abnormal_DNA_repair0.95706855
110MP0003656_abnormal_erythrocyte_physiolo0.95636191
111MP0000428_abnormal_craniofacial_morphol0.95278029
112MP0005375_adipose_tissue_phenotype0.95259904
113MP0002166_altered_tumor_susceptibility0.94821586
114MP0002089_abnormal_postnatal_growth/wei0.94023977
115MP0000598_abnormal_liver_morphology0.93839778
116MP0002060_abnormal_skin_morphology0.93604743
117MP0001958_emphysema0.92087107
118MP0001915_intracranial_hemorrhage0.92017283
119MP0000750_abnormal_muscle_regeneration0.92010750
120MP0000609_abnormal_liver_physiology0.90557459
121MP0008469_abnormal_protein_level0.90187405
122MP0001853_heart_inflammation0.89049086
123MP0004233_abnormal_muscle_weight0.88307269
124MP0000343_altered_response_to0.87648031
125MP0001661_extended_life_span0.87537309
126MP0010155_abnormal_intestine_physiology0.87229117
127MP0005310_abnormal_salivary_gland0.86315040
128MP0003329_amyloid_beta_deposits0.83803851
129MP0004185_abnormal_adipocyte_glucose0.83465084
130MP0001873_stomach_inflammation0.83432244
131MP0001348_abnormal_lacrimal_gland0.82602968
132MP0005621_abnormal_cell_physiology0.82367836
133MP0005390_skeleton_phenotype0.81907741
134MP0005384_cellular_phenotype0.81785696
135MP0000747_muscle_weakness0.81572759
136MP0002970_abnormal_white_adipose0.81280699
137MP0003567_abnormal_fetal_cardiomyocyte0.79426276
138MP0001216_abnormal_epidermal_layer0.79054340
139MP0001800_abnormal_humoral_immune0.77718939
140MP0004133_heterotaxia0.77294243
141MP0000678_abnormal_parathyroid_gland0.77190778
142MP0009931_abnormal_skin_appearance0.76407342
143MP0003866_abnormal_defecation0.75781788
144MP0005360_urolithiasis0.75755147
145MP0000003_abnormal_adipose_tissue0.74233274
146MP0002420_abnormal_adaptive_immunity0.73677892
147MP0001819_abnormal_immune_cell0.72491161
148MP0002282_abnormal_trachea_morphology0.66919007
149MP0005319_abnormal_enzyme/_coenzyme0.66603037
150MP0002135_abnormal_kidney_morphology0.66582115
151MP0003448_altered_tumor_morphology0.66419467
152MP0002452_abnormal_antigen_presenting0.66077535

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)3.68444201
2Selective tooth agenesis (HP:0001592)3.30093409
3Premature rupture of membranes (HP:0001788)3.25443322
4Abnormality of the nasal mucosa (HP:0000433)3.24537947
5Protrusio acetabuli (HP:0003179)3.23504705
6Eczematoid dermatitis (HP:0000976)3.16215097
7Nasal polyposis (HP:0100582)3.13421900
8Vertebral compression fractures (HP:0002953)3.04353825
9Abnormality of the lower motor neuron (HP:0002366)2.95278480
10Ependymoma (HP:0002888)2.93113881
11Abnormality of cells of the erythroid lineage (HP:0012130)2.92693949
12Reticulocytopenia (HP:0001896)2.91424652
13Chronic otitis media (HP:0000389)2.88466519
14Abnormality of macrophages (HP:0004311)2.82437575
15Microretrognathia (HP:0000308)2.78273620
16Multiple enchondromatosis (HP:0005701)2.71187116
17Recurrent abscess formation (HP:0002722)2.69189130
18Abnormal number of erythroid precursors (HP:0012131)2.64253164
19Recurrent bacterial skin infections (HP:0005406)2.61837761
20Spastic diplegia (HP:0001264)2.60291953
21Cerebral aneurysm (HP:0004944)2.57389104
22Angiofibromas (HP:0010615)2.54682577
23Adenoma sebaceum (HP:0009720)2.54682577
24Basal cell carcinoma (HP:0002671)2.54324180
25Colon cancer (HP:0003003)2.49121779
26Increased connective tissue (HP:0009025)2.47997907
27Thrombocytosis (HP:0001894)2.46099817
28Thin bony cortex (HP:0002753)2.43731795
29Centrally nucleated skeletal muscle fibers (HP:0003687)2.43494956
30Abnormality of liposaccharide metabolism (HP:0010968)2.39193246
31Abnormality of glycosphingolipid metabolism (HP:0004343)2.39193246
32Abnormality of glycolipid metabolism (HP:0010969)2.39193246
33Renal duplication (HP:0000075)2.33486348
34Hand muscle atrophy (HP:0009130)2.33407707
35Insomnia (HP:0100785)2.32225352
36Fatigue (HP:0012378)2.30183258
37Increased density of long bones (HP:0006392)2.29906680
38Oral leukoplakia (HP:0002745)2.27768202
39Trismus (HP:0000211)2.27599640
40Cortical dysplasia (HP:0002539)2.27512877
41Verrucae (HP:0200043)2.26511926
42Papilloma (HP:0012740)2.26511926
43Long palpebral fissure (HP:0000637)2.26433048
44Bowel diverticulosis (HP:0005222)2.23545528
45Genu recurvatum (HP:0002816)2.23412166
46Elfin facies (HP:0004428)2.22946311
47Increased variability in muscle fiber diameter (HP:0003557)2.21957620
48Pallor (HP:0000980)2.19679751
49Progressive muscle weakness (HP:0003323)2.19297204
50Disproportionate tall stature (HP:0001519)2.19086221
51Blue sclerae (HP:0000592)2.18826887
52Gastrointestinal stroma tumor (HP:0100723)2.18647807
53Poikiloderma (HP:0001029)2.18032950
54Increased nuchal translucency (HP:0010880)2.16451629
55Renovascular hypertension (HP:0100817)2.16271691
56Dysostosis multiplex (HP:0000943)2.15818794
57Rhabdomyolysis (HP:0003201)2.13487911
58Distal lower limb amyotrophy (HP:0008944)2.13083451
59Increased cerebral lipofuscin (HP:0011813)2.12577927
60IgM deficiency (HP:0002850)2.12225318
61Abnormality of skeletal muscle fiber size (HP:0012084)2.11849652
62Achilles tendon contracture (HP:0001771)2.09761638
63Long toe (HP:0010511)2.09660834
64Ragged-red muscle fibers (HP:0003200)2.09486813
65Polygenic inheritance (HP:0010982)2.08478117
66Colitis (HP:0002583)2.06191144
67Ankle contracture (HP:0006466)2.05658774
68Emphysema (HP:0002097)2.05401038
69Macrocytic anemia (HP:0001972)2.05274910
70Atrophy/Degeneration involving motor neurons (HP:0007373)2.05243456
71Distal lower limb muscle weakness (HP:0009053)2.04875138
72Mediastinal lymphadenopathy (HP:0100721)2.04871499
73Deep palmar crease (HP:0006191)2.04348403
74Amyotrophic lateral sclerosis (HP:0007354)2.04029129
75Abnormality of the Achilles tendon (HP:0005109)2.03399689
76Aplastic anemia (HP:0001915)2.02998729
77Upper limb amyotrophy (HP:0009129)2.02568459
78Distal upper limb amyotrophy (HP:0007149)2.02568459
79Hypercortisolism (HP:0001578)2.02541374
80Abnormal number of incisors (HP:0011064)2.00340827
81Polycythemia (HP:0001901)1.98765735
82Increased IgE level (HP:0003212)1.98276604
83High pitched voice (HP:0001620)1.97299658
84Loss of speech (HP:0002371)1.97045539
85Biconcave vertebral bodies (HP:0004586)1.96079713
86Neoplasm of the pancreas (HP:0002894)1.94794081
87Fragile skin (HP:0001030)1.94625494
88Obstructive lung disease (HP:0006536)1.94522729
89Chronic obstructive pulmonary disease (HP:0006510)1.94522729
90Intestinal polyp (HP:0005266)1.94340293
91Gingivitis (HP:0000230)1.94201795
92Mesangial abnormality (HP:0001966)1.93192535
93Degeneration of anterior horn cells (HP:0002398)1.92926020
94Abnormality of the anterior horn cell (HP:0006802)1.92926020
95Broad face (HP:0000283)1.92537107
96Radial bowing (HP:0002986)1.92478892
97Bicuspid aortic valve (HP:0001647)1.92096035
98Slender long bone (HP:0003100)1.91906860
99Syringomyelia (HP:0003396)1.91399198
100Spinal cord lesions (HP:0100561)1.91399198
101Hemorrhage of the eye (HP:0011885)1.91340167
102Asymmetry of the thorax (HP:0001555)1.91003786
103Cervical subluxation (HP:0003308)1.90255857
104Bowed forearm bones (HP:0003956)1.89791498
105Bowing of the arm (HP:0006488)1.89791498
106Recurrent bronchitis (HP:0002837)1.89518284
107Abnormal platelet function (HP:0011869)1.89513227
108Impaired platelet aggregation (HP:0003540)1.89513227
109Abnormality of the distal phalanges of the toes (HP:0010182)1.89483354
110Hypertensive crisis (HP:0100735)1.88911416
111Abnormality of the astrocytes (HP:0100707)1.88820498
112Astrocytoma (HP:0009592)1.88820498
113Recurrent viral infections (HP:0004429)1.88469807
114Abnormality of reticulocytes (HP:0004312)1.88397350
115Osteolytic defects of the phalanges of the hand (HP:0009771)1.88008557
116Osteolytic defects of the hand bones (HP:0009699)1.88008557
117Missing ribs (HP:0000921)1.87728378
118Pointed chin (HP:0000307)1.87571739
119Abnormality of the thoracic spine (HP:0100711)1.87224330
120Flat acetabular roof (HP:0003180)1.86815804
121Abnormality of the calcaneus (HP:0008364)1.86046258
122Gastrointestinal inflammation (HP:0004386)1.85711214
123Intestinal polyposis (HP:0200008)1.85312944
124Pelvic girdle muscle weakness (HP:0003749)1.82766210
125Striae distensae (HP:0001065)1.81856913
126Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.81652669
127Short 4th metacarpal (HP:0010044)1.81652669
128Myositis (HP:0100614)1.80507503
129Elbow flexion contracture (HP:0002987)1.80063173
130Nonimmune hydrops fetalis (HP:0001790)1.79335890
131Shallow orbits (HP:0000586)1.79325717
132Meningitis (HP:0001287)1.79308467
133Myocardial infarction (HP:0001658)1.79107989
134Spontaneous hematomas (HP:0007420)1.78482759
135Ulnar bowing (HP:0003031)1.78459037
136Panhypogammaglobulinemia (HP:0003139)1.76508650
137Abnormality of the 4th metacarpal (HP:0010012)1.76033369
138Abnormality of the motor neurons (HP:0002450)1.75885322
139Abnormal neuron morphology (HP:0012757)1.75885322
140Ankyloglossia (HP:0010296)1.75875419
141Interstitial pulmonary disease (HP:0006530)1.75873347
142Spondylolisthesis (HP:0003302)1.74710841
143Orchitis (HP:0100796)1.73912026
144Abnormality of oral frenula (HP:0000190)1.73124304
145Neoplasm of the rectum (HP:0100743)1.72306736
146Generalized amyotrophy (HP:0003700)1.71875295
147Upper motor neuron abnormality (HP:0002127)1.71375339
148Fibroma (HP:0010614)1.70600846
149Shoulder girdle muscle weakness (HP:0003547)1.70567533
150Aneurysm (HP:0002617)1.70485834
151Increased neuronal autofluorescent lipopigment (HP:0002074)1.70247664
152Cellulitis (HP:0100658)1.70242733
153Thoracic kyphosis (HP:0002942)1.70191827
154Increased serum ferritin (HP:0003281)1.69880609
155Proximal placement of thumb (HP:0009623)1.69876992
156Dilatation of the ascending aorta (HP:0005111)1.69563400
157Atrophic scars (HP:0001075)1.69411224
158Mitral valve prolapse (HP:0001634)1.69255296
159Recurrent gram-negative bacterial infections (HP:0005420)1.68762004
160Deviation of the thumb (HP:0009603)1.67437159
161Difficulty climbing stairs (HP:0003551)1.66338101
162Pseudobulbar signs (HP:0002200)1.65570426
163Asymmetric septal hypertrophy (HP:0001670)1.65130731
164Limb-girdle muscle atrophy (HP:0003797)1.65024485
165Urticaria (HP:0001025)1.64173392
166Hyperparathyroidism (HP:0000843)1.63964986
167Overriding aorta (HP:0002623)1.63382206
168Mitral regurgitation (HP:0001653)1.63357274
169Wormian bones (HP:0002645)1.62964688
170Neonatal onset (HP:0003623)1.62886123
171Natal tooth (HP:0000695)1.62453573
172Short nail (HP:0001799)1.61817257
173Inflammation of the large intestine (HP:0002037)1.61372351
174Peritonitis (HP:0002586)1.61283864
175Bone pain (HP:0002653)1.60794023
176Subacute progressive viral hepatitis (HP:0006572)1.60658400
177Segmental peripheral demyelination/remyelination (HP:0003481)1.60233124
178Spinal rigidity (HP:0003306)1.60067058
179Purpura (HP:0000979)1.58372033
180Gastrointestinal infarctions (HP:0005244)1.57484727
181Mucopolysacchariduria (HP:0008155)1.56890121
182Urinary glycosaminoglycan excretion (HP:0003541)1.56890121
183Abnormality of polysaccharide metabolism (HP:0011012)1.56698470
184Abnormality of glycosaminoglycan metabolism (HP:0004371)1.56698470
185Abnormality of mucopolysaccharide metabolism (HP:0011020)1.56698470

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.88578668
2EEF2K3.53024480
3PRPF4B3.50335688
4BUB13.40619813
5TRIB33.36376038
6MAP3K103.28293063
7PKN22.97892322
8IRAK32.81177935
9TESK22.51998377
10ERN12.35274243
11MAP4K12.23126548
12SCYL22.20874265
13DYRK32.17683237
14LRRK22.12372411
15RPS6KB22.07069948
16NEK21.96462188
17RIPK41.73601044
18RPS6KA41.64872063
19KDR1.64266950
20ZAP701.61683996
21PAK41.60077109
22FLT31.59311384
23PIM21.57623200
24EIF2AK11.57240593
25NEK11.57217148
26ICK1.54475662
27WEE11.51029513
28BCKDK1.49227467
29STK101.49041403
30MAP3K141.44865641
31PTK61.44359312
32IRAK41.40107222
33TLK11.38623631
34MAP3K31.37476223
35TESK11.36679206
36CDC71.34153484
37MAP3K111.31814256
38MAPKAPK31.31127331
39NME21.24612036
40TYK21.21625290
41MAP3K131.20302197
42TTN1.16210801
43MAP3K81.15956485
44GRK61.13991889
45BTK1.13538272
46CDK41.10983027
47TSSK61.08525197
48RIPK11.02928525
49MAP3K11.02199333
50KSR21.02134181
51PDGFRA1.01650134
52CDK121.00991397
53EPHA21.00462265
54CSK1.00041571
55TAOK10.98097618
56PRKD20.94693401
57CDC42BPA0.93545431
58FGFR40.91847165
59ARAF0.91388253
60EPHB10.91216035
61CSF1R0.90079937
62TGFBR10.89516776
63ALK0.88947732
64PASK0.88848081
65MAP2K30.88111905
66MOS0.86837733
67DDR20.81780619
68BLK0.81175580
69PRKD30.81051715
70MTOR0.79564895
71HIPK20.79135837
72SIK30.79126751
73MARK20.77765610
74PDK40.76958458
75PDK30.76958458
76TGFBR20.76674113
77JAK30.76604729
78CAMK1D0.76238557
79ILK0.74620451
80PDPK10.73833469
81PAK10.73074537
82BRAF0.72675918
83CDK70.71413095
84LATS20.69751390
85NEK90.69195491
86CDK60.69012621
87CDK190.68807153
88PRKCI0.68048589
89ACVR1B0.64423300
90PIM10.64403276
91SIK10.63657140
92IRAK20.63624244
93KIT0.62847643
94DYRK1B0.62342158
95RAF10.61373336
96AURKB0.60852467
97PLK10.60069699
98ITK0.59871889
99HCK0.57479800
100ATR0.54907007
101FGR0.54544931
102PTK20.53726508
103TBK10.52600568
104MAPK110.52585710
105DAPK30.52390468
106PAK20.51549305
107AURKA0.51517775
108IKBKE0.50838676
109JAK10.50300644
110IKBKB0.48674459
111TAOK20.47766681
112AKT20.47682878
113CHEK10.47640297
114FES0.47619902
115SYK0.46440656
116DAPK10.45902443
117SRPK10.45246324
118RPS6KA60.44929882
119SIK20.44901482
120MAPK120.44607616
121MAP2K20.42662042
122TTK0.41863170
123CDK20.41815527
124PDK10.41772560
125CLK10.41154282
126CCNB10.41031678
127RPS6KA10.40681258
128CDK90.38977980
129STK40.38181721
130BMX0.37761944
131BRSK10.37161699
132MAP3K60.36716491
133TNK20.36446713
134LYN0.36440801
135JAK20.36364427
136MAPKAPK20.34763239
137VRK20.34485526
138RPS6KC10.34429289
139RPS6KL10.34429289
140LCK0.32843978
141FGFR10.32693354
142RPS6KA20.31284429

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.48735920
2Ribosome_Homo sapiens_hsa030103.06570959
3Spliceosome_Homo sapiens_hsa030402.86022175
4Base excision repair_Homo sapiens_hsa034102.62812132
5Other glycan degradation_Homo sapiens_hsa005112.58078144
6One carbon pool by folate_Homo sapiens_hsa006702.52319163
7RNA transport_Homo sapiens_hsa030132.34869497
8Mismatch repair_Homo sapiens_hsa034302.30106388
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.15019767
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.14040252
11Biosynthesis of amino acids_Homo sapiens_hsa012302.10624468
12Pentose phosphate pathway_Homo sapiens_hsa000302.09321122
13Osteoclast differentiation_Homo sapiens_hsa043801.93552605
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.88929076
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.85500838
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.78873236
17Toll-like receptor signaling pathway_Homo sapiens_hsa046201.77826614
18Proteasome_Homo sapiens_hsa030501.76494985
19Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.75396313
20Leishmaniasis_Homo sapiens_hsa051401.75389698
21Cyanoamino acid metabolism_Homo sapiens_hsa004601.74324295
22Cell cycle_Homo sapiens_hsa041101.70849905
23Carbon metabolism_Homo sapiens_hsa012001.59884462
24NF-kappa B signaling pathway_Homo sapiens_hsa040641.53064897
25Chronic myeloid leukemia_Homo sapiens_hsa052201.47231302
26Antigen processing and presentation_Homo sapiens_hsa046121.46965782
27Primary immunodeficiency_Homo sapiens_hsa053401.45741595
28Pyrimidine metabolism_Homo sapiens_hsa002401.43635293
29Nucleotide excision repair_Homo sapiens_hsa034201.41300384
30Sulfur relay system_Homo sapiens_hsa041221.38168270
31Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.34723047
32Influenza A_Homo sapiens_hsa051641.33089878
33TNF signaling pathway_Homo sapiens_hsa046681.32096355
34AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.29833498
35Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.28899990
36mRNA surveillance pathway_Homo sapiens_hsa030151.28630692
37Selenocompound metabolism_Homo sapiens_hsa004501.26536776
38Malaria_Homo sapiens_hsa051441.26295431
39Tuberculosis_Homo sapiens_hsa051521.26035399
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.25010759
41Acute myeloid leukemia_Homo sapiens_hsa052211.24808349
42Glycosaminoglycan degradation_Homo sapiens_hsa005311.23591759
43Prion diseases_Homo sapiens_hsa050201.22982803
44Lysosome_Homo sapiens_hsa041421.22678932
45p53 signaling pathway_Homo sapiens_hsa041151.22428767
46RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.21064896
47Hepatitis C_Homo sapiens_hsa051601.19882535
48Bladder cancer_Homo sapiens_hsa052191.19595786
49Central carbon metabolism in cancer_Homo sapiens_hsa052301.11388883
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11300977
51Shigellosis_Homo sapiens_hsa051311.08353165
52Viral carcinogenesis_Homo sapiens_hsa052031.08193561
53RNA polymerase_Homo sapiens_hsa030201.07066839
54Thyroid cancer_Homo sapiens_hsa052161.05937468
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05756125
56Renal cell carcinoma_Homo sapiens_hsa052111.04776027
57HTLV-I infection_Homo sapiens_hsa051661.04411795
58Salmonella infection_Homo sapiens_hsa051321.03081693
59Allograft rejection_Homo sapiens_hsa053301.00761497
60Staphylococcus aureus infection_Homo sapiens_hsa051501.00068900
61Homologous recombination_Homo sapiens_hsa034400.99117374
62Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.98581321
63Amoebiasis_Homo sapiens_hsa051460.97673633
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.97055142
65Prostate cancer_Homo sapiens_hsa052150.97053909
66Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96922283
67Colorectal cancer_Homo sapiens_hsa052100.96457595
68Small cell lung cancer_Homo sapiens_hsa052220.95630335
69mTOR signaling pathway_Homo sapiens_hsa041500.95339788
70Epstein-Barr virus infection_Homo sapiens_hsa051690.94248766
71Fructose and mannose metabolism_Homo sapiens_hsa000510.93680919
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.92375854
73Galactose metabolism_Homo sapiens_hsa000520.92266905
74Lysine degradation_Homo sapiens_hsa003100.90163528
75Folate biosynthesis_Homo sapiens_hsa007900.90070496
76Autoimmune thyroid disease_Homo sapiens_hsa053200.88351350
77B cell receptor signaling pathway_Homo sapiens_hsa046620.88093923
78RNA degradation_Homo sapiens_hsa030180.87776063
79Pyruvate metabolism_Homo sapiens_hsa006200.87235596
80Focal adhesion_Homo sapiens_hsa045100.86050022
81Prolactin signaling pathway_Homo sapiens_hsa049170.84626213
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.83241650
83VEGF signaling pathway_Homo sapiens_hsa043700.82404631
84Graft-versus-host disease_Homo sapiens_hsa053320.81902107
85Non-small cell lung cancer_Homo sapiens_hsa052230.81076675
86Herpes simplex infection_Homo sapiens_hsa051680.80355873
87Chemokine signaling pathway_Homo sapiens_hsa040620.80225556
88Glioma_Homo sapiens_hsa052140.79777155
89Apoptosis_Homo sapiens_hsa042100.79010070
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.77434658
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.76873209
92Pertussis_Homo sapiens_hsa051330.76485467
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75854149
94Drug metabolism - other enzymes_Homo sapiens_hsa009830.75703611
95Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.75261241
96Fatty acid degradation_Homo sapiens_hsa000710.74205325
97Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.73853407
98Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.73232635
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.72884384
100Systemic lupus erythematosus_Homo sapiens_hsa053220.70766012
101Oocyte meiosis_Homo sapiens_hsa041140.70577686
102Pancreatic cancer_Homo sapiens_hsa052120.69816635
103ErbB signaling pathway_Homo sapiens_hsa040120.68656901
104Insulin signaling pathway_Homo sapiens_hsa049100.68654661
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68571829
106Phagosome_Homo sapiens_hsa041450.67716376
107T cell receptor signaling pathway_Homo sapiens_hsa046600.67222418
108Hematopoietic cell lineage_Homo sapiens_hsa046400.67161928
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66783586
110Intestinal immune network for IgA production_Homo sapiens_hsa046720.66354358
111Notch signaling pathway_Homo sapiens_hsa043300.66091056
112Hepatitis B_Homo sapiens_hsa051610.60828873
113Alcoholism_Homo sapiens_hsa050340.60726622
114African trypanosomiasis_Homo sapiens_hsa051430.59831734
115Proteoglycans in cancer_Homo sapiens_hsa052050.59060807
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.58969270
117Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.58899242
118Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.58876562
119Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.58271702
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55524338
121N-Glycan biosynthesis_Homo sapiens_hsa005100.55453386
122Adherens junction_Homo sapiens_hsa045200.55247535
123Endometrial cancer_Homo sapiens_hsa052130.55066370
124Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.54256047
125HIF-1 signaling pathway_Homo sapiens_hsa040660.53880146
126AMPK signaling pathway_Homo sapiens_hsa041520.53826743
127FoxO signaling pathway_Homo sapiens_hsa040680.53231879
128Measles_Homo sapiens_hsa051620.52592150
129Inositol phosphate metabolism_Homo sapiens_hsa005620.52048640
130Leukocyte transendothelial migration_Homo sapiens_hsa046700.52027479
131MicroRNAs in cancer_Homo sapiens_hsa052060.50965696
132Arginine biosynthesis_Homo sapiens_hsa002200.49375543
133Insulin resistance_Homo sapiens_hsa049310.47868336
134Viral myocarditis_Homo sapiens_hsa054160.46878612
135Legionellosis_Homo sapiens_hsa051340.45855832
136Purine metabolism_Homo sapiens_hsa002300.44828697
137Toxoplasmosis_Homo sapiens_hsa051450.44569937
138Hippo signaling pathway_Homo sapiens_hsa043900.44492977
139Adipocytokine signaling pathway_Homo sapiens_hsa049200.43674322
140Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40877341
141Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.40824846
142Endocytosis_Homo sapiens_hsa041440.40632284
143Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.40027135
144Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39717313
145Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39187290
146Transcriptional misregulation in cancer_Homo sapiens_hsa052020.38077657
147Fatty acid metabolism_Homo sapiens_hsa012120.36455943
148Pathways in cancer_Homo sapiens_hsa052000.35028772

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