CCDC71L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.21071735
2modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.21071735
3positive regulation by organism of defense response of other organism involved in symbiotic interact5.21071735
4modulation by symbiont of host immune response (GO:0052553)5.21071735
5positive regulation by symbiont of host defense response (GO:0052509)5.21071735
6modulation by symbiont of host defense response (GO:0052031)5.21071735
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.67116539
8neutrophil activation involved in immune response (GO:0002283)4.50308884
9macrophage activation involved in immune response (GO:0002281)4.20679718
10negative regulation of cell killing (GO:0031342)3.93547932
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.93547932
12lipopolysaccharide-mediated signaling pathway (GO:0031663)3.87169937
13regulation of interferon-beta biosynthetic process (GO:0045357)3.79522165
14response to peptidoglycan (GO:0032494)3.69158106
15regulation of vitamin D biosynthetic process (GO:0060556)3.67475432
16granulocyte activation (GO:0036230)3.62171956
17positive regulation of gamma-delta T cell activation (GO:0046645)3.60322271
18respiratory burst (GO:0045730)3.59298470
19positive regulation of chemokine biosynthetic process (GO:0045080)3.57735860
20adhesion of symbiont to host cell (GO:0044650)3.57253600
21virion attachment to host cell (GO:0019062)3.57253600
22positive regulation of interferon-alpha production (GO:0032727)3.56914622
23protein localization to endosome (GO:0036010)3.55011854
24neutrophil activation (GO:0042119)3.54077853
25regulation of dendritic cell antigen processing and presentation (GO:0002604)3.52137073
26response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.49969503
27response to host immune response (GO:0052572)3.49969503
28immunoglobulin mediated immune response (GO:0016064)3.46069224
29regulation of interleukin-12 biosynthetic process (GO:0045075)3.44085524
30skin morphogenesis (GO:0043589)3.42716035
31response to muramyl dipeptide (GO:0032495)3.42709901
32regulation of interferon-alpha production (GO:0032647)3.42151737
33positive regulation of antigen processing and presentation (GO:0002579)3.37127087
34endodermal cell differentiation (GO:0035987)3.35861073
35negative regulation of erythrocyte differentiation (GO:0045647)3.32491205
36embryonic process involved in female pregnancy (GO:0060136)3.30384776
37positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.29423431
38positive regulation of endothelial cell apoptotic process (GO:2000353)3.28212735
39antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.26734140
40antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.26734140
41antigen processing and presentation of endogenous antigen (GO:0019883)3.26706502
42regulation of early endosome to late endosome transport (GO:2000641)3.26015307
43cell migration involved in heart development (GO:0060973)3.24215323
44response to host defenses (GO:0052200)3.19656857
45response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.19656857
46response to host (GO:0075136)3.19656857
47positive regulation of cellular amide metabolic process (GO:0034250)3.17606877
48myeloid dendritic cell differentiation (GO:0043011)3.15528647
49myeloid cell activation involved in immune response (GO:0002275)3.15221187
50positive regulation of heat generation (GO:0031652)3.10682438
51adhesion of symbiont to host (GO:0044406)3.04672432
52regulation of T-helper 2 cell differentiation (GO:0045628)3.02078141
53positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.01315173
54decidualization (GO:0046697)3.00600651
55regulation of fever generation (GO:0031620)2.99252942
56NIK/NF-kappaB signaling (GO:0038061)2.98730851
57interferon-gamma-mediated signaling pathway (GO:0060333)2.98320991
58positive regulation of interleukin-12 production (GO:0032735)2.98279249
59leukocyte aggregation (GO:0070486)2.96829149
60hydrogen peroxide biosynthetic process (GO:0050665)2.95367311
61superoxide anion generation (GO:0042554)2.94724462
62production of molecular mediator involved in inflammatory response (GO:0002532)2.93959816
63hyaluronan catabolic process (GO:0030214)2.93612402
64negative regulation of adherens junction organization (GO:1903392)2.92677586
65negative regulation of focal adhesion assembly (GO:0051895)2.92677586
66negative regulation of cell junction assembly (GO:1901889)2.92677586
67Arp2/3 complex-mediated actin nucleation (GO:0034314)2.92667652
68lymphocyte chemotaxis (GO:0048247)2.92260996
69regulation of antigen processing and presentation (GO:0002577)2.91011904
70regulation of membrane protein ectodomain proteolysis (GO:0051043)2.90976543
71substrate-dependent cell migration (GO:0006929)2.90973073
72leukocyte cell-cell adhesion (GO:0007159)2.89808920
73JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.89487309
74myeloid dendritic cell activation (GO:0001773)2.88481635
75regulation of vitamin metabolic process (GO:0030656)2.88378051
76positive regulation of blood vessel endothelial cell migration (GO:0043536)2.86694233
77positive regulation of interleukin-1 secretion (GO:0050716)2.86496770
78macrophage activation (GO:0042116)2.86155034
79positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.83109462
80positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.82971352
81cellular response to zinc ion (GO:0071294)2.82658698
82regulation of cholesterol storage (GO:0010885)2.82487380
83low-density lipoprotein particle clearance (GO:0034383)2.82027062
84collagen fibril organization (GO:0030199)2.80456392
85regulation of T-helper 1 cell differentiation (GO:0045625)2.78973103
86regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.78323339
87hypotonic response (GO:0006971)2.76965971
88barbed-end actin filament capping (GO:0051016)2.75586403
89chronic inflammatory response (GO:0002544)2.75184291
90regulation of B cell receptor signaling pathway (GO:0050855)2.75167614
91negative regulation of interleukin-17 production (GO:0032700)2.74789192
92negative regulation of nitric oxide biosynthetic process (GO:0045019)2.73941303
93positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.73804158
94neutrophil chemotaxis (GO:0030593)2.72591146
95stress fiber assembly (GO:0043149)2.72499013
96protein heterotrimerization (GO:0070208)2.72210882
97negative regulation of interleukin-12 production (GO:0032695)2.69453689
98I-kappaB phosphorylation (GO:0007252)2.69444356
99response to type I interferon (GO:0034340)2.69113204
100T-helper 1 type immune response (GO:0042088)2.69108903
101cellular extravasation (GO:0045123)2.68894973
102positive regulation of natural killer cell differentiation (GO:0032825)2.68851695
103regulation of interleukin-1 secretion (GO:0050704)2.68808541
104detection of molecule of bacterial origin (GO:0032490)2.67858026
105positive regulation of mast cell activation (GO:0033005)2.67556258
106regulation of chemokine biosynthetic process (GO:0045073)2.67129415
107regulation of mononuclear cell migration (GO:0071675)2.66817541
108modulation by symbiont of host cellular process (GO:0044068)2.66639880
109positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.66189795
110regulation of interleukin-12 production (GO:0032655)2.65183903
111dendritic cell differentiation (GO:0097028)2.64529446
112negative regulation of fatty acid transport (GO:2000192)2.64480591
113neutrophil migration (GO:1990266)2.64039608
114microglial cell activation (GO:0001774)2.63648592
115type I interferon signaling pathway (GO:0060337)2.63491020
116cellular response to type I interferon (GO:0071357)2.63491020
117mature B cell differentiation (GO:0002335)2.63050493
118myeloid leukocyte activation (GO:0002274)2.63029289
119response to laminar fluid shear stress (GO:0034616)2.62511049
120germinal center formation (GO:0002467)2.62379799
121endocardial cushion development (GO:0003197)2.62244306
122positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.61132997
123negative regulation of smooth muscle cell migration (GO:0014912)2.60800841
124positive regulation of p38MAPK cascade (GO:1900745)2.60537346
125defense response to protozoan (GO:0042832)2.59827370
126positive regulation of receptor recycling (GO:0001921)2.58606559
127blood vessel maturation (GO:0001955)2.58089419
128regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.58055235
129mannose metabolic process (GO:0006013)2.57677456
130positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.57194550
131positive regulation of chemokine production (GO:0032722)2.57047523
132positive regulation of mast cell activation involved in immune response (GO:0033008)2.56759324
133positive regulation of mast cell degranulation (GO:0043306)2.56759324
134positive regulation of macrophage cytokine production (GO:0060907)2.56709355
135cell adhesion mediated by integrin (GO:0033627)2.56217700
136negative regulation of lipid storage (GO:0010888)2.55790736
137positive regulation of cytokine biosynthetic process (GO:0042108)2.55510328
138natural killer cell mediated cytotoxicity (GO:0042267)2.55455557
139natural killer cell mediated immunity (GO:0002228)2.55455557
140regulation of transforming growth factor beta1 production (GO:0032908)2.55205628
141positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.53656088
142vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.53130871
143positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.52554384
144collagen metabolic process (GO:0032963)2.51834642
145oxygen transport (GO:0015671)2.48749841
146cellular response to thyroid hormone stimulus (GO:0097067)2.48740554
147regulation of type I interferon-mediated signaling pathway (GO:0060338)2.46311355
148extracellular matrix assembly (GO:0085029)2.43220262
149negative regulation of anoikis (GO:2000811)2.42551647
150collagen catabolic process (GO:0030574)2.41224816
151apoptotic cell clearance (GO:0043277)2.37912277
152ovulation from ovarian follicle (GO:0001542)2.34528777
153endocytic recycling (GO:0032456)2.33725990
154regulation of macrophage cytokine production (GO:0010935)2.33608641
155positive regulation of fibroblast migration (GO:0010763)2.33322842
156cellular response to interferon-alpha (GO:0035457)2.31774538
157fibril organization (GO:0097435)2.30685974
158positive regulation of astrocyte differentiation (GO:0048711)2.29071569
159multicellular organismal macromolecule metabolic process (GO:0044259)2.28446121
160response to vitamin D (GO:0033280)2.28074315
161response to fluid shear stress (GO:0034405)2.27393792
162positive regulation of osteoblast proliferation (GO:0033690)2.27371211
163tooth mineralization (GO:0034505)2.27285859
164negative regulation of protein localization to plasma membrane (GO:1903077)2.26229009
165wound healing, spreading of epidermal cells (GO:0035313)2.25807240
166regulation of nitric oxide biosynthetic process (GO:0045428)2.24123202

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse5.04509973
2IRF8_22096565_ChIP-ChIP_GC-B_Human4.98011578
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.02697407
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.78141050
5IRF8_27001747_Chip-Seq_BMDM_Mouse3.67415213
6SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.66586483
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.62004996
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.50062162
9Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.27195963
10RARG_19884340_ChIP-ChIP_MEFs_Mouse3.26260534
11NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.24675891
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.21074563
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.03247730
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.00532822
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.97727721
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.91875944
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.77209428
18IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.66479761
19RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.21350996
20TP63_17297297_ChIP-ChIP_HaCaT_Human2.19784341
21STAT4_19710469_ChIP-ChIP_TH1__Mouse2.15708743
22BRD4_27068464_Chip-Seq_AML-cells_Mouse2.13773142
23RUNX_20019798_ChIP-Seq_JUKART_Human2.11096589
24VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.10361890
25CLOCK_20551151_ChIP-Seq_293T_Human2.05735831
26STAT6_21828071_ChIP-Seq_BEAS2B_Human2.04747816
27STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.84875156
28VDR_24787735_ChIP-Seq_THP-1_Human1.82438126
29WT1_19549856_ChIP-ChIP_CCG9911_Human1.82111672
30NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.80772429
31VDR_24763502_ChIP-Seq_THP-1_Human1.80167137
32SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.79410326
33FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.78731850
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.74632608
35PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.73930170
36TRIM28_21343339_ChIP-Seq_HEK293_Human1.73783556
37MAF_26560356_Chip-Seq_TH1_Human1.71840337
38MYB_26560356_Chip-Seq_TH2_Human1.66427838
39LXR_22292898_ChIP-Seq_THP-1_Human1.65283245
40SPI1_23127762_ChIP-Seq_K562_Human1.64431577
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.63235042
42GATA1_19941826_ChIP-Seq_K562_Human1.61869866
43RUNX1_22412390_ChIP-Seq_EML_Mouse1.61182958
44SCL_19346495_ChIP-Seq_HPC-7_Human1.59185989
45GATA1_22025678_ChIP-Seq_K562_Human1.59150870
46CDX2_19796622_ChIP-Seq_MESCs_Mouse1.57424385
47PU_27001747_Chip-Seq_BMDM_Mouse1.54577430
48VDR_21846776_ChIP-Seq_THP-1_Human1.53324438
49SPI1_23547873_ChIP-Seq_NB4_Human1.53145364
50NCOR1_26117541_ChIP-Seq_K562_Human1.52982831
51KDM2B_26808549_Chip-Seq_K562_Human1.50199257
52P300_27058665_Chip-Seq_ZR-75-30cells_Human1.49900898
53PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.49394939
54TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.46386103
55TCF7_22412390_ChIP-Seq_EML_Mouse1.43655147
56BRD4_25478319_ChIP-Seq_HGPS_Human1.43160798
57TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.42702443
58RACK7_27058665_Chip-Seq_MCF-7_Human1.42264610
59KDM2B_26808549_Chip-Seq_SUP-B15_Human1.42030846
60UBF1/2_26484160_Chip-Seq_HMECs_Human1.41981526
61PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.40218354
62GATA2_19941826_ChIP-Seq_K562_Human1.39411333
63GATA2_21666600_ChIP-Seq_HMVEC_Human1.38709063
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37955182
65FOXO3_23340844_ChIP-Seq_DLD1_Human1.35542932
66ESR2_21235772_ChIP-Seq_MCF-7_Human1.35165771
67SMC1_22415368_ChIP-Seq_MEFs_Mouse1.35006827
68MYB_26560356_Chip-Seq_TH1_Human1.34976982
69SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.34431122
70KDM2B_26808549_Chip-Seq_DND41_Human1.33723045
71SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.33517911
72NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33303943
73UTX_26944678_Chip-Seq_JUKART_Human1.30340274
74ELK3_25401928_ChIP-Seq_HUVEC_Human1.29128039
75PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.26073187
76STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.25438119
77WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24276339
78E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.23863966
79UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.23430317
80ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.22752112
81NFIB_24661679_ChIP-Seq_LUNG_Mouse1.19975825
82ATF3_27146783_Chip-Seq_COLON_Human1.19568935
83SOX2_20726797_ChIP-Seq_SW620_Human1.18685345
84RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.18018234
85GATA3_27048872_Chip-Seq_THYMUS_Human1.15693993
86SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.15261360
87SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.15261360
88CDX2_20551321_ChIP-Seq_CACO-2_Human1.14731124
89TP53_22127205_ChIP-Seq_IMR90_Human1.14175517
90TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.13566081
91FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.12949988
92KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12932936
93GATA1_19941827_ChIP-Seq_MEL_Mouse1.12198824
94KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.12182468
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11763452
96IKZF1_21737484_ChIP-ChIP_HCT116_Human1.11506266
97KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11155770
98KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.11059089
99PPAR_26484153_Chip-Seq_NCI-H1993_Human1.10581392
100TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.09472249
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07455209
102ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07273870
103MYC_22102868_ChIP-Seq_BL_Human1.07128253
104CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.07038106
105SALL4_18804426_ChIP-ChIP_XEN_Mouse1.07013967
106MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.06642001
107CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06175166
108GATA2_22383799_ChIP-Seq_G1ME_Mouse1.04477553
109CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01052360
110ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00592778
111CTCF_27219007_Chip-Seq_ERYTHROID_Human0.99535411
112NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.99401313
113NRF2_20460467_ChIP-Seq_MEFs_Mouse0.99401313
114GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98108470
115JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97124512
116BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.96428301
117EGR1_19032775_ChIP-ChIP_M12_Human0.96281192
118RXR_22108803_ChIP-Seq_LS180_Human0.93561173
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92601302
120GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92566277
121FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.91559392
122GATA1_22383799_ChIP-Seq_G1ME_Mouse0.90237665
123LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89595873
124TP53_16413492_ChIP-PET_HCT116_Human0.88938234
125CJUN_26792858_Chip-Seq_BT549_Human0.85534596
126MAF_26560356_Chip-Seq_TH2_Human0.84677953
127GATA3_26560356_Chip-Seq_TH2_Human0.84624904
128KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.84342597
129ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.84165155
130CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.83996590
131KDM2B_26808549_Chip-Seq_JURKAT_Human0.83570462

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation4.13592223
2MP0001835_abnormal_antigen_presentation3.74951633
3MP0003436_decreased_susceptibility_to3.47797653
4MP0009785_altered_susceptibility_to3.36409848
5MP0000685_abnormal_immune_system3.01704559
6MP0002148_abnormal_hypersensitivity_rea2.99557853
7MP0004510_myositis2.96430491
8MP0005000_abnormal_immune_tolerance2.92821021
9MP0003279_aneurysm2.89089131
10MP0005387_immune_system_phenotype2.88459483
11MP0001790_abnormal_immune_system2.88459483
12MP0002419_abnormal_innate_immunity2.81129399
13MP0006082_CNS_inflammation2.65242229
14MP0005025_abnormal_response_to2.64957866
15MP0002452_abnormal_antigen_presenting2.56928416
16MP0005671_abnormal_response_to2.55233927
17MP0005503_abnormal_tendon_morphology2.45621627
18MP0004272_abnormal_basement_membrane2.44776740
19MP0001800_abnormal_humoral_immune2.42583280
20MP0003300_gastrointestinal_ulcer2.31242271
21MP0005275_abnormal_skin_tensile2.30623053
22MP0002723_abnormal_immune_serum2.30529456
23MP0002138_abnormal_hepatobiliary_system2.26943779
24MP0001819_abnormal_immune_cell2.20633706
25MP0002420_abnormal_adaptive_immunity2.17952164
26MP0003724_increased_susceptibility_to2.16505899
27MP0001542_abnormal_bone_strength2.13727698
28MP0005058_abnormal_lysosome_morphology2.09120691
29MP0004947_skin_inflammation2.07307487
30MP0010234_abnormal_vibrissa_follicle2.07236522
31MP0005464_abnormal_platelet_physiology2.04392874
32MP0008004_abnormal_stomach_pH1.92626112
33MP0010155_abnormal_intestine_physiology1.89275145
34MP0003656_abnormal_erythrocyte_physiolo1.87298976
35MP0005023_abnormal_wound_healing1.86812331
36MP0002006_tumorigenesis1.85453590
37MP0001533_abnormal_skeleton_physiology1.85123977
38MP0003448_altered_tumor_morphology1.83839055
39MP0005076_abnormal_cell_differentiation1.82700297
40MP0002405_respiratory_system_inflammati1.79985318
41MP0005451_abnormal_body_composition1.74078631
42MP0001845_abnormal_inflammatory_respons1.71801563
43MP0002166_altered_tumor_susceptibility1.65433767
44MP0003191_abnormal_cellular_cholesterol1.65128100
45MP0009333_abnormal_splenocyte_physiolog1.59880382
46MP0005310_abnormal_salivary_gland1.59568433
47MP0002398_abnormal_bone_marrow1.58671968
48MP0005167_abnormal_blood-brain_barrier1.57688783
49MP0000716_abnormal_immune_system1.56275138
50MP0010352_gastrointestinal_tract_polyps1.54720145
51MP0009764_decreased_sensitivity_to1.53662412
52MP0000343_altered_response_to1.53237157
53MP0003075_altered_response_to1.48533872
54MP0003950_abnormal_plasma_membrane1.45846466
55MP0000604_amyloidosis1.44346642
56MP0001545_abnormal_hematopoietic_system1.41146248
57MP0005397_hematopoietic_system_phenotyp1.41146248
58MP0002998_abnormal_bone_remodeling1.38722794
59MP0008469_abnormal_protein_level1.37141876
60MP0009278_abnormal_bone_marrow1.36521218
61MP0001853_heart_inflammation1.36321977
62MP0000858_altered_metastatic_potential1.36100070
63MP0002295_abnormal_pulmonary_circulatio1.32848390
64MP0000569_abnormal_digit_pigmentation1.31560932
65MP0005166_decreased_susceptibility_to1.30889690
66MP0005257_abnormal_intraocular_pressure1.30022410
67MP0003828_pulmonary_edema1.27995857
68MP0005595_abnormal_vascular_smooth1.27811570
69MP0002429_abnormal_blood_cell1.26947135
70MP0009384_cardiac_valve_regurgitation1.26940448
71MP0003705_abnormal_hypodermis_morpholog1.26238211
72MP0003566_abnormal_cell_adhesion1.25937912
73MP0000689_abnormal_spleen_morphology1.24970229
74MP0010307_abnormal_tumor_latency1.23877337
75MP0008260_abnormal_autophagy1.22595975
76MP0002722_abnormal_immune_system1.22566252
77MP0003866_abnormal_defecation1.16673423
78MP0010368_abnormal_lymphatic_system1.13434276
79MP0005508_abnormal_skeleton_morphology1.13043607
80MP0003172_abnormal_lysosome_physiology1.11216717
81MP0003045_fibrosis1.10110505
82MP0003091_abnormal_cell_migration1.08251127
83MP0002060_abnormal_skin_morphology1.06955378
84MP0000490_abnormal_crypts_of1.05102006
85MP0002254_reproductive_system_inflammat1.03500151
86MP0003453_abnormal_keratinocyte_physiol1.01524343
87MP0004883_abnormal_blood_vessel1.01519304
88MP0006054_spinal_hemorrhage1.01016977
89MP0001851_eye_inflammation0.99745318
90MP0005164_abnormal_response_to0.98002609
91MP0002896_abnormal_bone_mineralization0.96941752
92MP0001663_abnormal_digestive_system0.96826831
93MP0004185_abnormal_adipocyte_glucose0.94700994
94MP0001243_abnormal_dermal_layer0.93831337
95MP0001873_stomach_inflammation0.93415142
96MP0008438_abnormal_cutaneous_collagen0.91451087
97MP0002332_abnormal_exercise_endurance0.90023625
98MP0000750_abnormal_muscle_regeneration0.88100481
99MP0001958_emphysema0.87041896
100MP0001849_ear_inflammation0.86835795
101MP0004233_abnormal_muscle_weight0.84239153
102MP0000249_abnormal_blood_vessel0.83542086
103MP0002933_joint_inflammation0.82505667
104MP0005390_skeleton_phenotype0.80917850
105MP0003183_abnormal_peptide_metabolism0.80365814
106MP0001915_intracranial_hemorrhage0.80084029
107MP0005174_abnormal_tail_pigmentation0.79445635
108MP0005165_increased_susceptibility_to0.79281623
109MP0004858_abnormal_nervous_system0.79010159
110MP0003941_abnormal_skin_development0.77144182
111MP0001348_abnormal_lacrimal_gland0.76808252
112MP0004808_abnormal_hematopoietic_stem0.75971609
113MP0009763_increased_sensitivity_to0.75106206
114MP0005623_abnormal_meninges_morphology0.74696878
115MP0005197_abnormal_uvea_morphology0.73779374
116MP0003795_abnormal_bone_structure0.70782813
117MP0003763_abnormal_thymus_physiology0.69009541
118MP0001614_abnormal_blood_vessel0.68913724
119MP0000465_gastrointestinal_hemorrhage0.68200847
120MP0000733_abnormal_muscle_development0.67527860
121MP0000703_abnormal_thymus_morphology0.67164621
122MP0000767_abnormal_smooth_muscle0.65243684
123MP0010678_abnormal_skin_adnexa0.65089714
124MP0009840_abnormal_foam_cell0.64830415
125MP0002277_abnormal_respiratory_mucosa0.64410051
126MP0002136_abnormal_kidney_physiology0.63751665
127MP0001879_abnormal_lymphatic_vessel0.60594149
128MP0002877_abnormal_melanocyte_morpholog0.58807629
129MP0003690_abnormal_glial_cell0.57510027
130MP0009931_abnormal_skin_appearance0.56559762

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.17749650
2Recurrent abscess formation (HP:0002722)6.03119988
3Recurrent bacterial skin infections (HP:0005406)5.51318650
4Premature rupture of membranes (HP:0001788)5.44447364
5Protrusio acetabuli (HP:0003179)5.15360540
6Recurrent gram-negative bacterial infections (HP:0005420)4.76942821
7Abnormality of macrophages (HP:0004311)4.58972134
8Autoimmune thrombocytopenia (HP:0001973)4.40424689
9Mediastinal lymphadenopathy (HP:0100721)4.36858548
10Orchitis (HP:0100796)3.89965277
11Recurrent fungal infections (HP:0002841)3.83865647
12Myositis (HP:0100614)3.75063846
13Elevated erythrocyte sedimentation rate (HP:0003565)3.72185935
14Retrobulbar optic neuritis (HP:0100654)3.69336201
15Optic neuritis (HP:0100653)3.69336201
16Aortic aneurysm (HP:0004942)3.62997294
17Stomatitis (HP:0010280)3.59984965
18Recurrent skin infections (HP:0001581)3.58158135
19Prostate neoplasm (HP:0100787)3.49201871
20Recurrent viral infections (HP:0004429)3.48682810
21Pustule (HP:0200039)3.47269982
22Cellulitis (HP:0100658)3.44246007
23Gingivitis (HP:0000230)3.42300756
24Obstructive lung disease (HP:0006536)3.36671263
25Chronic obstructive pulmonary disease (HP:0006510)3.36671263
26Aortic dissection (HP:0002647)3.25803934
27Polycythemia (HP:0001901)3.25246503
28Vasculitis (HP:0002633)3.24632801
29Vacuolated lymphocytes (HP:0001922)3.24462723
30Disinhibition (HP:0000734)3.17687305
31Ankle contracture (HP:0006466)3.14688813
32Hematochezia (HP:0002573)3.13721385
33Abnormality of glycolipid metabolism (HP:0010969)3.10213282
34Abnormality of liposaccharide metabolism (HP:0010968)3.10213282
35Abnormality of glycosphingolipid metabolism (HP:0004343)3.10213282
36Vascular tortuosity (HP:0004948)3.03985484
37Dilatation of the ascending aorta (HP:0005111)3.02615976
38Follicular hyperkeratosis (HP:0007502)3.00209229
39Increased cerebral lipofuscin (HP:0011813)2.93105300
40Vertebral compression fractures (HP:0002953)2.83699730
41Chronic mucocutaneous candidiasis (HP:0002728)2.82343410
42Recurrent cutaneous fungal infections (HP:0011370)2.82343410
43Urticaria (HP:0001025)2.81538559
44Genu recurvatum (HP:0002816)2.79371121
45Meningitis (HP:0001287)2.79273249
46Cervical subluxation (HP:0003308)2.77404997
47Spinal rigidity (HP:0003306)2.76730515
48Bladder diverticulum (HP:0000015)2.73924991
49Osteomyelitis (HP:0002754)2.69890957
50Thick nail (HP:0001805)2.68913670
51Arterial tortuosity (HP:0005116)2.67198969
52Soft skin (HP:0000977)2.66419244
53Atrophic scars (HP:0001075)2.65390718
54Chronic otitis media (HP:0000389)2.64205482
55Leukocytosis (HP:0001974)2.63239595
56Slender build (HP:0001533)2.62826668
57Blue sclerae (HP:0000592)2.62526872
58Pulmonary infiltrates (HP:0002113)2.62288721
59Fragile skin (HP:0001030)2.58846161
60Increased variability in muscle fiber diameter (HP:0003557)2.57420897
61Wormian bones (HP:0002645)2.53306513
62Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.49957061
63Increased neuronal autofluorescent lipopigment (HP:0002074)2.48655944
64Type 1 muscle fiber predominance (HP:0003803)2.46108694
65Nonimmune hydrops fetalis (HP:0001790)2.45080170
66Arterial thrombosis (HP:0004420)2.44973822
67Systemic lupus erythematosus (HP:0002725)2.44763687
68Cerebral aneurysm (HP:0004944)2.43205546
69Increased connective tissue (HP:0009025)2.41341237
70Interstitial pulmonary disease (HP:0006530)2.40962824
71Basal ganglia calcification (HP:0002135)2.37256774
72Myocardial infarction (HP:0001658)2.35876050
73Petechiae (HP:0000967)2.35615350
74Recurrent pneumonia (HP:0006532)2.33883937
75Colitis (HP:0002583)2.33650496
76Peritonitis (HP:0002586)2.31151750
77Spontaneous hematomas (HP:0007420)2.30905294
78Poikilocytosis (HP:0004447)2.29184740
79Periodontitis (HP:0000704)2.26678627
80Achilles tendon contracture (HP:0001771)2.26406111
81Keratoconjunctivitis sicca (HP:0001097)2.26370277
82Aneurysm (HP:0002617)2.25006736
83Inflammation of the large intestine (HP:0002037)2.22776905
84Abnormal hemoglobin (HP:0011902)2.21514015
85Dysostosis multiplex (HP:0000943)2.21386862
86Mitral valve prolapse (HP:0001634)2.20566802
87Abnormality of skeletal muscle fiber size (HP:0012084)2.20065625
88Recurrent lower respiratory tract infections (HP:0002783)2.19139689
89Tetraparesis (HP:0002273)2.18326065
90Disproportionate tall stature (HP:0001519)2.17363806
91Thin bony cortex (HP:0002753)2.16138919
92Hemoptysis (HP:0002105)2.15447087
93Abnormality of T cell number (HP:0011839)2.14617023
94Increased IgE level (HP:0003212)2.12806896
95Elbow flexion contracture (HP:0002987)2.12709857
96Abnormality of the heme biosynthetic pathway (HP:0010472)2.11386568
97Gastrointestinal infarctions (HP:0005244)2.10516978
98Acanthocytosis (HP:0001927)2.10070099
99Persistence of primary teeth (HP:0006335)2.09086023
100Joint laxity (HP:0001388)2.08436859
101Overgrowth (HP:0001548)2.07305820
102Gastrointestinal stroma tumor (HP:0100723)2.07305169
103Axonal loss (HP:0003447)2.07252303
104Broad metatarsal (HP:0001783)2.06684488
105Keratoconjunctivitis (HP:0001096)2.04661328
106Osteolytic defects of the hand bones (HP:0009699)2.04477257
107Osteolytic defects of the phalanges of the hand (HP:0009771)2.04477257
108Agammaglobulinemia (HP:0004432)2.04449430
109Gastrointestinal inflammation (HP:0004386)2.03643135
110Shallow orbits (HP:0000586)2.03529583
111Abnormal delayed hypersensitivity skin test (HP:0002963)2.03081730
112Prolonged bleeding time (HP:0003010)2.02972425
113Increased density of long bones (HP:0006392)2.01786932
114Gingival bleeding (HP:0000225)2.01569998
115Abnormality of the Achilles tendon (HP:0005109)1.99138859
116Hypertensive crisis (HP:0100735)1.98483167
117Sepsis (HP:0100806)1.97291046
118T lymphocytopenia (HP:0005403)1.97122989
119Joint stiffness (HP:0001387)1.97046537
120Emphysema (HP:0002097)1.96933708
121Inappropriate behavior (HP:0000719)1.95980399
122Mucopolysacchariduria (HP:0008155)1.94808351
123Urinary glycosaminoglycan excretion (HP:0003541)1.94808351
124Thyroiditis (HP:0100646)1.94609893
125Hyperextensible skin (HP:0000974)1.93535388
126Abnormality of polysaccharide metabolism (HP:0011012)1.93377790
127Abnormality of glycosaminoglycan metabolism (HP:0004371)1.93377790
128Abnormality of mucopolysaccharide metabolism (HP:0011020)1.93377790
129Abnormality of the prostate (HP:0008775)1.92884506
130Absent frontal sinuses (HP:0002688)1.92681663
131Mitral regurgitation (HP:0001653)1.90752151
132Abnormality of dentin (HP:0010299)1.89815863
133Reticulocytosis (HP:0001923)1.88441509
134Recurrent bronchitis (HP:0002837)1.87096146
135Abnormality of complement system (HP:0005339)1.86715958
136Glomerulonephritis (HP:0000099)1.86509970
137Autoimmune hemolytic anemia (HP:0001890)1.86411624
138Wrist flexion contracture (HP:0001239)1.86247677
139Porencephaly (HP:0002132)1.84550476
140Viral hepatitis (HP:0006562)1.83951421
141Bone pain (HP:0002653)1.83516069
142Encephalitis (HP:0002383)1.81781986
143Venous abnormality (HP:0002624)1.81524215
144Cupped ribs (HP:0000887)1.81260391
145Segmental peripheral demyelination/remyelination (HP:0003481)1.81014864
146Increased IgM level (HP:0003496)1.80478287
147Abnormality of the vasculature of the conjunctiva (HP:0008054)1.80157511
148Aortic regurgitation (HP:0001659)1.79671394
149Arthralgia (HP:0002829)1.79592662
150Esophageal varix (HP:0002040)1.79278926
151Abnormal platelet volume (HP:0011876)1.78891073
152Eosinophilia (HP:0001880)1.78171855
153Lymphopenia (HP:0001888)1.77154090
154Abnormality of cells of the lymphoid lineage (HP:0012140)1.76857774
155Abnormality of the acetabulum (HP:0003170)1.76669643
156Ulnar bowing (HP:0003031)1.76348420
157Epistaxis (HP:0000421)1.75971881
158Chest pain (HP:0100749)1.75857236
159Distal upper limb amyotrophy (HP:0007149)1.75548320
160Upper limb amyotrophy (HP:0009129)1.75548320
161Abnormality of the pericardium (HP:0001697)1.75300736
162Papilledema (HP:0001085)1.74655924
163Distal lower limb amyotrophy (HP:0008944)1.74646277
164Spondylolisthesis (HP:0003302)1.74487404
165Thoracolumbar scoliosis (HP:0002944)1.74227097
166Mildly elevated creatine phosphokinase (HP:0008180)1.73780136
167Biconcave vertebral bodies (HP:0004586)1.73636476
168Ovoid vertebral bodies (HP:0003300)1.73243862
169Aortic valve stenosis (HP:0001650)1.73004308
170Spinal cord lesions (HP:0100561)1.72870966
171Syringomyelia (HP:0003396)1.72870966
172Coxa vara (HP:0002812)1.71699152
173Bowel diverticulosis (HP:0005222)1.67879139

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.63598702
2MAP3K143.83371180
3AKT33.31013816
4MST1R3.28353654
5TBK13.10571665
6PRPF4B2.73077807
7DDR22.56564185
8TAOK22.37818307
9PIK3CA2.35144597
10PDGFRA2.35090674
11MAP4K12.33421169
12TYK22.18261657
13NME22.13789068
14IKBKE2.12191363
15BLK2.10966071
16IRAK42.10717901
17IKBKB2.05720796
18MYLK2.00588587
19JAK31.89371279
20KSR21.83962872
21ERN11.74012742
22MAP3K101.68564326
23JAK11.64219453
24SIK11.50823532
25BMX1.50395766
26STK101.49494671
27KIT1.48140979
28MST41.47924609
29LATS21.46123576
30IRAK31.43256502
31RIPK11.40918139
32ICK1.40704403
33GRK61.40491282
34CDC42BPA1.40458154
35FRK1.38860884
36CHUK1.38758320
37FGR1.38704786
38CSK1.36345534
39PBK1.36278709
40EPHB11.36244366
41PRKD21.35346852
42MAP3K21.32876288
43SYK1.32152186
44TRIB31.32077484
45PTK21.30201176
46TXK1.22304487
47TGFBR21.20805167
48HCK1.19373034
49TAOK31.18372922
50MAP3K131.16545032
51PIM11.15384653
52JAK21.11727812
53FES1.07643236
54PAK21.07262112
55LCK1.07216366
56ZAP701.06915070
57LYN1.05666528
58TTN1.01500657
59PKN21.01081135
60BMPR21.00601527
61PTK61.00404140
62DMPK0.99877646
63EPHB20.97326792
64DYRK30.97265211
65PIM20.96530021
66NTRK10.95459883
67MAP2K30.94570526
68ABL20.94552442
69PAK40.94065095
70CLK10.86198062
71STK40.83966495
72STK30.83860147
73LRRK20.82866425
74SIK20.81176343
75MARK30.80899121
76BRAF0.80222808
77CDK120.79584332
78IRAK10.78673563
79EPHA30.77313464
80RPS6KC10.76363224
81RPS6KL10.76363224
82BTK0.74875632
83RPS6KA20.74407404
84MAP3K10.74248809
85RET0.73351249
86MET0.71565069
87RPS6KA40.71531282
88FGFR30.70464456
89STK240.69440249
90MAPK70.69215668
91HIPK20.68988086
92SCYL20.68764984
93PDGFRB0.67658650
94EGFR0.67045184
95MAP3K50.66843755
96ITK0.66570515
97FGFR40.66269011
98MTOR0.65586093
99ARAF0.65164638
100MAP3K80.64423968
101GSK3A0.64183412
102PIK3CG0.64182991
103CSF1R0.63976641
104DYRK1B0.63919109
105MAP2K20.63782255
106ABL10.63494397
107MAPK40.62962853
108PTK2B0.61790597
109TEC0.61677399
110ERBB40.61518251
111CDK90.61193092
112TESK10.61087473
113IRAK20.60926008
114PRKG20.59815764
115CDK60.59443965
116PRKCQ0.59104304
117KSR10.59058194
118FYN0.58830045
119TIE10.58158604
120RPS6KA60.56002844
121NEK90.54898419
122ALK0.53082772
123MARK20.52320876
124MAP2K10.52320592
125TRPM70.52106560
126MAP3K60.49430498
127PRKCD0.48874760
128GRK70.48653285
129TAOK10.48370819
130RAF10.47685629
131MATK0.46026459
132CAMK1D0.45581149
133STK380.44760108
134SMG10.44641655
135MAP3K110.44247308
136NME10.43295058
137YES10.41221407
138MOS0.41179792
139MAP3K30.39014642
140NLK0.38187175
141MAPKAPK20.37808116
142PDPK10.36481941

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.11069099
2Osteoclast differentiation_Homo sapiens_hsa043802.43631695
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.29755378
4Toll-like receptor signaling pathway_Homo sapiens_hsa046202.29080201
5Graft-versus-host disease_Homo sapiens_hsa053322.24415947
6NOD-like receptor signaling pathway_Homo sapiens_hsa046212.12472455
7Pertussis_Homo sapiens_hsa051332.06061768
8Tuberculosis_Homo sapiens_hsa051522.05193189
9TNF signaling pathway_Homo sapiens_hsa046681.91735412
10Malaria_Homo sapiens_hsa051441.91549027
11Legionellosis_Homo sapiens_hsa051341.86436618
12B cell receptor signaling pathway_Homo sapiens_hsa046621.82830411
13RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.70958805
14Staphylococcus aureus infection_Homo sapiens_hsa051501.70163651
15Toxoplasmosis_Homo sapiens_hsa051451.68007534
16Salmonella infection_Homo sapiens_hsa051321.66761705
17Measles_Homo sapiens_hsa051621.66099610
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.65851531
19Hematopoietic cell lineage_Homo sapiens_hsa046401.63456768
20Allograft rejection_Homo sapiens_hsa053301.61780449
21Prion diseases_Homo sapiens_hsa050201.59638456
22Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.59272442
23Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.55685178
24Rheumatoid arthritis_Homo sapiens_hsa053231.50719620
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.49133186
26Influenza A_Homo sapiens_hsa051641.47559351
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.42283131
28Shigellosis_Homo sapiens_hsa051311.40407632
29ECM-receptor interaction_Homo sapiens_hsa045121.39443579
30Apoptosis_Homo sapiens_hsa042101.37528123
31Chemokine signaling pathway_Homo sapiens_hsa040621.34551939
32African trypanosomiasis_Homo sapiens_hsa051431.32461818
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.31176018
34Chronic myeloid leukemia_Homo sapiens_hsa052201.27297764
35Asthma_Homo sapiens_hsa053101.24567940
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23461955
37T cell receptor signaling pathway_Homo sapiens_hsa046601.21757186
38Phagosome_Homo sapiens_hsa041451.21212650
39Hepatitis B_Homo sapiens_hsa051611.19993897
40Antigen processing and presentation_Homo sapiens_hsa046121.17101777
41Primary immunodeficiency_Homo sapiens_hsa053401.16590636
42Leukocyte transendothelial migration_Homo sapiens_hsa046701.13811834
43Jak-STAT signaling pathway_Homo sapiens_hsa046301.13588727
44Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.13046612
45Lysosome_Homo sapiens_hsa041421.12099725
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.11453227
47Herpes simplex infection_Homo sapiens_hsa051681.11151385
48Viral myocarditis_Homo sapiens_hsa054161.10835999
49Mineral absorption_Homo sapiens_hsa049781.09417492
50Type I diabetes mellitus_Homo sapiens_hsa049401.08810546
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07433884
52Pancreatic cancer_Homo sapiens_hsa052121.07152424
53Amoebiasis_Homo sapiens_hsa051461.05698002
54Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.05270684
55Hepatitis C_Homo sapiens_hsa051601.04899871
56Complement and coagulation cascades_Homo sapiens_hsa046100.97433995
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.94989822
58Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94530474
59Platelet activation_Homo sapiens_hsa046110.93982507
60Acute myeloid leukemia_Homo sapiens_hsa052210.93016031
61Small cell lung cancer_Homo sapiens_hsa052220.89859908
62Melanoma_Homo sapiens_hsa052180.88468189
63Type II diabetes mellitus_Homo sapiens_hsa049300.88182368
64Dorso-ventral axis formation_Homo sapiens_hsa043200.83417274
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.83139062
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.82358407
67VEGF signaling pathway_Homo sapiens_hsa043700.79771283
68Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79398091
69Glycosaminoglycan degradation_Homo sapiens_hsa005310.78736661
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77664580
71Endometrial cancer_Homo sapiens_hsa052130.76016531
72Adipocytokine signaling pathway_Homo sapiens_hsa049200.75815442
73Central carbon metabolism in cancer_Homo sapiens_hsa052300.73003032
74Notch signaling pathway_Homo sapiens_hsa043300.72181594
75Other glycan degradation_Homo sapiens_hsa005110.71881032
76Renal cell carcinoma_Homo sapiens_hsa052110.71360271
77Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70597893
78Glioma_Homo sapiens_hsa052140.69613499
79Proteoglycans in cancer_Homo sapiens_hsa052050.69494945
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68390007
81PI3K-Akt signaling pathway_Homo sapiens_hsa041510.68385233
82Pathways in cancer_Homo sapiens_hsa052000.68319173
83Prolactin signaling pathway_Homo sapiens_hsa049170.68235311
84Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67402449
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.67332739
86HIF-1 signaling pathway_Homo sapiens_hsa040660.67177093
87Autoimmune thyroid disease_Homo sapiens_hsa053200.65370345
88Protein digestion and absorption_Homo sapiens_hsa049740.63637745
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62708021
90mTOR signaling pathway_Homo sapiens_hsa041500.61869146
91Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.61512511
92Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60438596
93Non-small cell lung cancer_Homo sapiens_hsa052230.58968501
94MicroRNAs in cancer_Homo sapiens_hsa052060.58753120
95Viral carcinogenesis_Homo sapiens_hsa052030.58336234
96Rap1 signaling pathway_Homo sapiens_hsa040150.57632837
97FoxO signaling pathway_Homo sapiens_hsa040680.56508217
98Thyroid cancer_Homo sapiens_hsa052160.55331759
99Focal adhesion_Homo sapiens_hsa045100.55192330
100Endocytosis_Homo sapiens_hsa041440.54402112
101GnRH signaling pathway_Homo sapiens_hsa049120.51476200
102SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50920064
103Prostate cancer_Homo sapiens_hsa052150.50419592
104Systemic lupus erythematosus_Homo sapiens_hsa053220.49538783
105Adherens junction_Homo sapiens_hsa045200.49248510
106Renin-angiotensin system_Homo sapiens_hsa046140.47896262
107Colorectal cancer_Homo sapiens_hsa052100.47528402
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47229477
109MAPK signaling pathway_Homo sapiens_hsa040100.46230406
110Bladder cancer_Homo sapiens_hsa052190.45744306
111Phospholipase D signaling pathway_Homo sapiens_hsa040720.45695060
112Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.44782176
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44636109
114Insulin resistance_Homo sapiens_hsa049310.44570106
115Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44139970
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40460967
117ErbB signaling pathway_Homo sapiens_hsa040120.40336547
118HTLV-I infection_Homo sapiens_hsa051660.38623398
119Choline metabolism in cancer_Homo sapiens_hsa052310.36964372

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