CCDC74A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axoneme assembly (GO:0035082)6.02731833
2left/right pattern formation (GO:0060972)5.65215071
3neuronal action potential propagation (GO:0019227)5.46935255
4synaptic vesicle maturation (GO:0016188)5.33451195
5cilium or flagellum-dependent cell motility (GO:0001539)5.15243099
6left/right axis specification (GO:0070986)5.03650890
7acrosome reaction (GO:0007340)4.95281498
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.94642692
9intraciliary transport (GO:0042073)4.87393260
10regulation of short-term neuronal synaptic plasticity (GO:0048172)4.82063870
11locomotory exploration behavior (GO:0035641)4.75252376
12synaptic vesicle exocytosis (GO:0016079)4.73811394
13substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.69369152
14substrate-independent telencephalic tangential migration (GO:0021826)4.69369152
15axonemal dynein complex assembly (GO:0070286)4.68881153
16glutamate secretion (GO:0014047)4.64575110
17cilium organization (GO:0044782)4.52627581
18ribosomal small subunit assembly (GO:0000028)4.41837425
19cilium assembly (GO:0042384)4.41380055
20regulation of synaptic vesicle exocytosis (GO:2000300)4.37297246
21nonmotile primary cilium assembly (GO:0035058)4.32676245
22calcium ion-dependent exocytosis (GO:0017156)4.31763938
23microtubule bundle formation (GO:0001578)4.28596695
24regulation of microtubule-based movement (GO:0060632)4.16783446
25cilium morphogenesis (GO:0060271)4.11014019
26fusion of sperm to egg plasma membrane (GO:0007342)4.10528758
27cilium movement (GO:0003341)4.07913730
28motile cilium assembly (GO:0044458)4.02884854
29positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.94808468
30sperm motility (GO:0030317)3.93727746
31regulation of synaptic vesicle transport (GO:1902803)3.93612380
32centriole assembly (GO:0098534)3.92010330
33viral transcription (GO:0019083)3.89516450
34negative regulation of inclusion body assembly (GO:0090084)3.87621109
35acrosome assembly (GO:0001675)3.85507259
36vocalization behavior (GO:0071625)3.85094228
37membrane depolarization during action potential (GO:0086010)3.81764233
38pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.79489136
39epithelial cilium movement (GO:0003351)3.78477618
40layer formation in cerebral cortex (GO:0021819)3.75932207
41translational termination (GO:0006415)3.72945514
42cerebellar Purkinje cell differentiation (GO:0021702)3.72020861
43neurotransmitter secretion (GO:0007269)3.71422973
44ionotropic glutamate receptor signaling pathway (GO:0035235)3.70310244
45cellular potassium ion homeostasis (GO:0030007)3.68364089
46negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.68178509
47exploration behavior (GO:0035640)3.67294196
48detection of temperature stimulus (GO:0016048)3.63957310
49positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.63945068
50centriole replication (GO:0007099)3.61948750
51sodium ion export (GO:0071436)3.59287712
52protein localization to synapse (GO:0035418)3.58460010
53neuromuscular process controlling posture (GO:0050884)3.57880880
54cell migration in hindbrain (GO:0021535)3.55259493
55proline transport (GO:0015824)3.52293077
56gamma-aminobutyric acid transport (GO:0015812)3.50185661
57negative regulation of T cell differentiation in thymus (GO:0033085)3.47973457
58base-excision repair, AP site formation (GO:0006285)3.47962901
59regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.47614121
60plasma membrane fusion (GO:0045026)3.45940884
61synaptic transmission, glutamatergic (GO:0035249)3.45240054
62establishment of monopolar cell polarity (GO:0061162)3.43920857
63establishment or maintenance of monopolar cell polarity (GO:0061339)3.43920857
64detection of temperature stimulus involved in sensory perception (GO:0050961)3.42812160
65detection of temperature stimulus involved in sensory perception of pain (GO:0050965)3.42812160
66negative regulation of dendrite morphogenesis (GO:0050774)3.39705380
67cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.38449662
68cerebellar granule cell differentiation (GO:0021707)3.37801020
69cell proliferation in forebrain (GO:0021846)3.34156549
70ribosomal small subunit biogenesis (GO:0042274)3.33319842
71regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.33267511
72neuron cell-cell adhesion (GO:0007158)3.31441285
73glutamate receptor signaling pathway (GO:0007215)3.31136429
74cellular component assembly involved in morphogenesis (GO:0010927)3.28728254
75tongue development (GO:0043586)3.27188609
76regulation of neuronal synaptic plasticity (GO:0048168)3.24696737
77synaptic vesicle docking involved in exocytosis (GO:0016081)3.23342009
78microtubule depolymerization (GO:0007019)3.22171320
79smoothened signaling pathway (GO:0007224)3.21549008
80regulation of neurotransmitter secretion (GO:0046928)3.20366383
81transmission of nerve impulse (GO:0019226)3.19941360
82multicellular organism reproduction (GO:0032504)3.18592723
83cell wall macromolecule metabolic process (GO:0044036)3.18166408
84cell wall macromolecule catabolic process (GO:0016998)3.18166408
85pyrimidine nucleotide catabolic process (GO:0006244)3.16946928
86primary alcohol catabolic process (GO:0034310)3.16045680
87synaptic vesicle endocytosis (GO:0048488)3.15113147
88cell communication by electrical coupling (GO:0010644)3.14944364
89positive regulation of potassium ion transmembrane transport (GO:1901381)3.14791911
90SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.13971077
91regulation of glutamate receptor signaling pathway (GO:1900449)3.12718559
92maturation of SSU-rRNA (GO:0030490)3.12024501
93piRNA metabolic process (GO:0034587)3.11750247
94neuron-neuron synaptic transmission (GO:0007270)3.11360007
95protein localization to cilium (GO:0061512)3.10793006
96cotranslational protein targeting to membrane (GO:0006613)3.10381165
97translational elongation (GO:0006414)3.10240165
98establishment of protein localization to mitochondrial membrane (GO:0090151)3.09442356
99sperm capacitation (GO:0048240)3.08771066
100protein targeting to ER (GO:0045047)3.06885292
101somite development (GO:0061053)3.06829850
102neurotransmitter transport (GO:0006836)3.06809172
103establishment of apical/basal cell polarity (GO:0035089)3.05498078
104nucleoside diphosphate phosphorylation (GO:0006165)3.03479948
105GTP biosynthetic process (GO:0006183)3.03356170
106regulation of vesicle fusion (GO:0031338)3.01815019
107neuromuscular process controlling balance (GO:0050885)3.01716480
108cellular protein complex disassembly (GO:0043624)3.00266532
109regulation of inclusion body assembly (GO:0090083)3.00247107
110calcium-mediated signaling using intracellular calcium source (GO:0035584)2.99921203
111membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.99032563
112vesicle transport along microtubule (GO:0047496)2.98226697
113innervation (GO:0060384)2.98130804
114epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.96845080
115membrane repolarization (GO:0086009)2.95737565
116regulation of cilium movement (GO:0003352)2.95577711
117regulation of synapse structural plasticity (GO:0051823)2.95390930
118axon cargo transport (GO:0008088)2.93474727
119cerebral cortex radially oriented cell migration (GO:0021799)2.93439659
120regulation of neurotransmitter transport (GO:0051588)2.92287755
121protein polyglutamylation (GO:0018095)2.91848566
122sperm-egg recognition (GO:0035036)2.91449062
123CTP biosynthetic process (GO:0006241)2.91368935
124CTP metabolic process (GO:0046036)2.91368935
125ventricular system development (GO:0021591)2.91208837
126establishment of protein localization to endoplasmic reticulum (GO:0072599)2.91080302
127long-term memory (GO:0007616)2.90248084
128negative regulation of microtubule polymerization (GO:0031115)2.89432196
129membrane depolarization (GO:0051899)2.89093154
130regulation of long-term neuronal synaptic plasticity (GO:0048169)2.88574083
131protein localization to endoplasmic reticulum (GO:0070972)2.86997206
132response to pheromone (GO:0019236)2.86536593
133microtubule severing (GO:0051013)2.86344061
134negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.84931454
135regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.84901372
136regulation of excitatory postsynaptic membrane potential (GO:0060079)2.84792691
137adult walking behavior (GO:0007628)2.83317905
138spermatid development (GO:0007286)2.83266565
139nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.82871481
140positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.82055771
141viral life cycle (GO:0019058)2.81355231
142activation of protein kinase A activity (GO:0034199)2.81316757
143cell projection assembly (GO:0030031)2.81083279
144regulation of neurotransmitter levels (GO:0001505)2.80818914
145vitamin transmembrane transport (GO:0035461)2.79817981
146establishment of planar polarity (GO:0001736)2.79314908
147establishment of tissue polarity (GO:0007164)2.79314908
148organelle transport along microtubule (GO:0072384)2.78867977
149determination of left/right symmetry (GO:0007368)2.78736795
150protein complex disassembly (GO:0043241)2.77815127
151cell differentiation in hindbrain (GO:0021533)2.76815471
152neuronal ion channel clustering (GO:0045161)2.76005805
153pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.75739147
154microtubule polymerization or depolymerization (GO:0031109)2.75332364
155neuromuscular process (GO:0050905)2.71326198
156retinal rod cell development (GO:0046548)2.71068734
157microtubule-based movement (GO:0007018)2.70918653
158gamma-aminobutyric acid signaling pathway (GO:0007214)2.70513092
159pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.69716738
160tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.69175715
161RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.69175715
162neuron fate determination (GO:0048664)2.68166806
163macromolecular complex disassembly (GO:0032984)2.66267422
164UTP biosynthetic process (GO:0006228)2.65911772
165brain morphogenesis (GO:0048854)2.65401874
166pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.64991716
167photoreceptor cell maintenance (GO:0045494)2.62694989
168determination of bilateral symmetry (GO:0009855)2.62510202
169dorsal/ventral pattern formation (GO:0009953)2.62043871
170pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.61449897
171lateral sprouting from an epithelium (GO:0060601)2.57645067
172specification of symmetry (GO:0009799)2.56289541
173mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.54708246
174lung epithelium development (GO:0060428)2.53259384
175behavioral response to nicotine (GO:0035095)2.53189927
176pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.49276790
177ATP synthesis coupled proton transport (GO:0015986)2.48986858
178energy coupled proton transport, down electrochemical gradient (GO:0015985)2.48986858
179postsynaptic membrane organization (GO:0001941)2.46990789
180limb development (GO:0060173)2.45753187
181appendage development (GO:0048736)2.45753187
182response to xenobiotic stimulus (GO:0009410)2.45477924
183UTP metabolic process (GO:0046051)2.44518655
184neuronal stem cell maintenance (GO:0097150)2.44056295
185short-term memory (GO:0007614)2.43155658
186terpenoid biosynthetic process (GO:0016114)2.38849623
187camera-type eye morphogenesis (GO:0048593)2.38787705

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.97746738
2EZH2_22144423_ChIP-Seq_EOC_Human5.77819741
3REST_21632747_ChIP-Seq_MESCs_Mouse2.77210731
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.46712729
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.45639424
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.45337132
7SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42285775
8MTF2_20144788_ChIP-Seq_MESCs_Mouse2.35509974
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.20423880
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.19461312
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.19461312
12ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.18134117
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.17767966
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.17357964
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.12674145
16GBX2_23144817_ChIP-Seq_PC3_Human2.10326346
17DROSHA_22980978_ChIP-Seq_HELA_Human2.09793000
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.09583845
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.04930550
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04670534
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.00215915
22IRF1_19129219_ChIP-ChIP_H3396_Human2.00060719
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.97753073
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.97024072
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.91614781
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.89464996
27SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.86571325
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79097746
29SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.76712218
30HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.74693701
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72865353
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.72732171
33ZNF274_21170338_ChIP-Seq_K562_Hela1.66955758
34VDR_22108803_ChIP-Seq_LS180_Human1.63925170
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.61177334
36CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60431946
37SMAD4_21799915_ChIP-Seq_A2780_Human1.60134979
38JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.59514108
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.58907252
40MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.56543703
41EED_16625203_ChIP-ChIP_MESCs_Mouse1.56533904
42RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.49731839
43MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.49710741
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43793329
45AR_21572438_ChIP-Seq_LNCaP_Human1.41225854
46ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.40262951
47CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.37096643
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37003754
49TAF15_26573619_Chip-Seq_HEK293_Human1.36163850
50GABP_19822575_ChIP-Seq_HepG2_Human1.35724573
51ERG_21242973_ChIP-ChIP_JURKAT_Human1.35185021
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.32482792
53P68_20966046_ChIP-Seq_HELA_Human1.32177125
54GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.31080070
55ETS1_20019798_ChIP-Seq_JURKAT_Human1.30365924
56SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29337989
57PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.28486499
58EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.28355196
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27448585
60CTCF_20526341_ChIP-Seq_ESCs_Human1.26925522
61CBX2_27304074_Chip-Seq_ESCs_Mouse1.26146229
62RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.25065399
63CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23715270
64KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22329549
65AR_25329375_ChIP-Seq_VCAP_Human1.21819281
66CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21467832
67TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19766637
68FOXP1_21924763_ChIP-Seq_HESCs_Human1.17596165
69NR3C1_23031785_ChIP-Seq_PC12_Mouse1.16077942
70TET1_21490601_ChIP-Seq_MESCs_Mouse1.15942580
71XRN2_22483619_ChIP-Seq_HELA_Human1.15600695
72YY1_22570637_ChIP-Seq_MALME-3M_Human1.15466321
73STAT3_23295773_ChIP-Seq_U87_Human1.15334686
74SMAD3_21741376_ChIP-Seq_ESCs_Human1.14155781
75BMI1_23680149_ChIP-Seq_NPCS_Mouse1.13539327
76SMC4_20622854_ChIP-Seq_HELA_Human1.12649901
77RNF2_27304074_Chip-Seq_NSC_Mouse1.11647535
78RING1B_27294783_Chip-Seq_ESCs_Mouse1.11108293
79TTF2_22483619_ChIP-Seq_HELA_Human1.10916890
80TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10655050
81OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.10526923
82ELK4_26923725_Chip-Seq_MESODERM_Mouse1.10089788
83MYC_18940864_ChIP-ChIP_HL60_Human1.09991942
84PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.08977675
85SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08974502
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08591211
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08591211
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.08582180
89E2F1_17053090_ChIP-ChIP_MCF-7_Human1.08401689
90P300_19829295_ChIP-Seq_ESCs_Human1.07702453
91WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06831077
92ERA_21632823_ChIP-Seq_H3396_Human1.06184245
93ZFP57_27257070_Chip-Seq_ESCs_Mouse1.05707993
94ELF1_20517297_ChIP-Seq_JURKAT_Human1.05459725
95EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05068821
96TCF4_23295773_ChIP-Seq_U87_Human1.04852667
97TP53_20018659_ChIP-ChIP_R1E_Mouse1.04713159
98* AR_19668381_ChIP-Seq_PC3_Human1.04502991
99SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04105264
100KDM2B_26808549_Chip-Seq_K562_Human1.03738995
101TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.02846087
102POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02528430
103BCAT_22108803_ChIP-Seq_LS180_Human1.01556951
104GATA1_26923725_Chip-Seq_HPCs_Mouse1.01438637
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00982811
106SMAD4_21741376_ChIP-Seq_EPCs_Human1.00948972
107GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00897745
108PHF8_20622854_ChIP-Seq_HELA_Human0.99703099
109ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.99463865
110MYC_18358816_ChIP-ChIP_MESCs_Mouse0.99386311
111NCOR_22424771_ChIP-Seq_293T_Human0.98909222
112SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.98804222
113EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.98695698
114SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98431731
115GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98103108
116E2F1_20622854_ChIP-Seq_HELA_Human0.97240637
117SMAD3_21741376_ChIP-Seq_EPCs_Human0.96834605
118* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.96681641
119OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.96478345
120SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96312963
121TAF2_19829295_ChIP-Seq_ESCs_Human0.96139959
122KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.95933057
123* EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95876976
124CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.95078296
125PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94852021
126MYC_19829295_ChIP-Seq_ESCs_Human0.94503124
127CTCF_27219007_Chip-Seq_Bcells_Human0.94267702
128SOX2_16153702_ChIP-ChIP_HESCs_Human0.93969536
129RAD21_21589869_ChIP-Seq_MESCs_Mouse0.93877373
130KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93452310
131KDM2B_26808549_Chip-Seq_REH_Human0.93259962
132MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.93239364
133RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.92278505
134FLI1_21867929_ChIP-Seq_TH2_Mouse0.92007000
135MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.91689847
136P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91652018
137TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.90833908
138PIAS1_25552417_ChIP-Seq_VCAP_Human0.89717706
139SA1_27219007_Chip-Seq_Bcells_Human0.89463562
140POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89435029
141NANOG_20526341_ChIP-Seq_ESCs_Human0.89406806
142RUNX2_22187159_ChIP-Seq_PCA_Human0.89301646
143EST1_17652178_ChIP-ChIP_JURKAT_Human0.89163966
144MYC_18555785_ChIP-Seq_MESCs_Mouse0.89101424
145ETV2_25802403_ChIP-Seq_MESCs_Mouse0.89007488
146CTCF_18555785_ChIP-Seq_MESCs_Mouse0.88839694
147RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.88428978
148DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.88203363
149UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87880782
150CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86915310
151SOX2_21211035_ChIP-Seq_LN229_Human0.86337421
152NANOG_18555785_Chip-Seq_ESCs_Mouse0.86068210
153NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85952094
154TDRD3_21172665_ChIP-Seq_MCF-7_Human0.85671562
155BCL6_27268052_Chip-Seq_Bcells_Human0.85449621
156TP53_22127205_ChIP-Seq_IMR90_Human0.85353136
157SMAD4_21741376_ChIP-Seq_HESCs_Human0.83440773
158PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.82424996
159RING1B_27294783_Chip-Seq_NPCs_Mouse0.81836903
160KLF4_19829295_ChIP-Seq_ESCs_Human0.80667322
161TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.80596738
162OCT1_27270436_Chip-Seq_PROSTATE_Human0.80570877

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.61337191
2MP0006292_abnormal_olfactory_placode4.33825598
3MP0005410_abnormal_fertilization4.06195875
4MP0008789_abnormal_olfactory_epithelium3.97576144
5MP0004270_analgesia3.77114424
6MP0001968_abnormal_touch/_nociception3.73840051
7MP0009046_muscle_twitch3.62984097
8MP0003880_abnormal_central_pattern3.55772036
9MP0002735_abnormal_chemical_nociception3.54759704
10MP0003635_abnormal_synaptic_transmissio3.47334627
11MP0002736_abnormal_nociception_after3.42400066
12MP0009379_abnormal_foot_pigmentation3.29950140
13MP0002734_abnormal_mechanical_nocicepti3.12484548
14MP0005377_hearing/vestibular/ear_phenot3.01806619
15MP0003878_abnormal_ear_physiology3.01806619
16MP0010030_abnormal_orbit_morphology2.83715285
17MP0004858_abnormal_nervous_system2.78363319
18MP0002064_seizures2.77236784
19MP0009745_abnormal_behavioral_response2.72859379
20MP0002733_abnormal_thermal_nociception2.72623160
21MP0000566_synostosis2.71286503
22MP0002272_abnormal_nervous_system2.63498497
23MP0002063_abnormal_learning/memory/cond2.59176073
24MP0001970_abnormal_pain_threshold2.51054828
25MP0003136_yellow_coat_color2.38909337
26MP0005423_abnormal_somatic_nervous2.36232861
27MP0004133_heterotaxia2.34333544
28MP0002572_abnormal_emotion/affect_behav2.29593199
29MP0006276_abnormal_autonomic_nervous2.20148888
30MP0003329_amyloid_beta_deposits2.18676254
31MP0001440_abnormal_grooming_behavior2.17728173
32MP0002067_abnormal_sensory_capabilities2.15676454
33MP0001293_anophthalmia2.14078950
34MP0008569_lethality_at_weaning2.12976028
35MP0001486_abnormal_startle_reflex2.10475548
36MP0002184_abnormal_innervation2.08165363
37MP0000049_abnormal_middle_ear1.97626626
38MP0008875_abnormal_xenobiotic_pharmacok1.88118843
39MP0001501_abnormal_sleep_pattern1.82160247
40MP0004811_abnormal_neuron_physiology1.77398720
41MP0000955_abnormal_spinal_cord1.77187697
42MP0003698_abnormal_male_reproductive1.72554782
43MP0002653_abnormal_ependyma_morphology1.70731954
44MP0002249_abnormal_larynx_morphology1.69692981
45MP0005248_abnormal_Harderian_gland1.69386677
46MP0002102_abnormal_ear_morphology1.64578085
47MP0000778_abnormal_nervous_system1.62124248
48MP0005623_abnormal_meninges_morphology1.56582347
49MP0003011_delayed_dark_adaptation1.54660857
50MP0002233_abnormal_nose_morphology1.53896941
51MP0002557_abnormal_social/conspecific_i1.50711265
52MP0001984_abnormal_olfaction1.47829433
53MP0000026_abnormal_inner_ear1.47246057
54MP0002882_abnormal_neuron_morphology1.45790741
55MP0009780_abnormal_chondrocyte_physiolo1.42472458
56MP0000631_abnormal_neuroendocrine_gland1.42373069
57MP0004924_abnormal_behavior1.36901679
58MP0005386_behavior/neurological_phenoty1.36901679
59MP0002066_abnormal_motor_capabilities/c1.36312069
60MP0003123_paternal_imprinting1.36285113
61MP0002234_abnormal_pharynx_morphology1.33836294
62MP0004142_abnormal_muscle_tone1.33489473
63MP0004145_abnormal_muscle_electrophysio1.31273997
64MP0003879_abnormal_hair_cell1.30620435
65MP0003937_abnormal_limbs/digits/tail_de1.28638126
66MP0001929_abnormal_gametogenesis1.27006440
67MP0003938_abnormal_ear_development1.26728427
68MP0003942_abnormal_urinary_system1.26248918
69MP0004885_abnormal_endolymph1.25644685
70MP0002909_abnormal_adrenal_gland1.25397094
71MP0003634_abnormal_glial_cell1.23037794
72MP0003633_abnormal_nervous_system1.22942656
73MP0001986_abnormal_taste_sensitivity1.21305739
74MP0002282_abnormal_trachea_morphology1.20341521
75MP0005389_reproductive_system_phenotype1.16773480
76MP0000751_myopathy1.16403504
77MP0003631_nervous_system_phenotype1.16221806
78MP0001905_abnormal_dopamine_level1.16117673
79MP0008877_abnormal_DNA_methylation1.14493468
80MP0002229_neurodegeneration1.13746679
81MP0005195_abnormal_posterior_eye1.13529801
82MP0002152_abnormal_brain_morphology1.11941469
83MP0004742_abnormal_vestibular_system1.11639295
84MP0000920_abnormal_myelination1.11232193
85MP0006072_abnormal_retinal_apoptosis1.10999293
86MP0001286_abnormal_eye_development1.09978720
87MP0009053_abnormal_anal_canal1.09712314
88MP0003121_genomic_imprinting1.09135065
89MP0003632_abnormal_nervous_system1.07691840
90MP0008995_early_reproductive_senescence1.06234248
91MP0001502_abnormal_circadian_rhythm1.05242504
92MP0003787_abnormal_imprinting1.04367056
93MP0002092_abnormal_eye_morphology1.03983035
94MP0002163_abnormal_gland_morphology1.02486252
95MP0005083_abnormal_biliary_tract1.01709580
96MP0005391_vision/eye_phenotype0.99755184
97MP0005645_abnormal_hypothalamus_physiol0.98367967
98MP0005253_abnormal_eye_physiology0.97090655
99MP0002277_abnormal_respiratory_mucosa0.96835536
100MP0000604_amyloidosis0.96705668
101MP0003646_muscle_fatigue0.95530541
102MP0000678_abnormal_parathyroid_gland0.95512947
103MP0002161_abnormal_fertility/fecundity0.94876029
104MP0002116_abnormal_craniofacial_bone0.94238491
105MP0002752_abnormal_somatic_nervous0.93983846
106MP0005646_abnormal_pituitary_gland0.93831971
107MP0002837_dystrophic_cardiac_calcinosis0.93591809
108MP0001299_abnormal_eye_distance/0.92753045
109MP0003755_abnormal_palate_morphology0.90281369
110MP0002132_abnormal_respiratory_system0.88889952
111MP0002638_abnormal_pupillary_reflex0.87857266
112MP0001348_abnormal_lacrimal_gland0.87504301
113MP0002938_white_spotting0.86461108
114MP0002822_catalepsy0.85802095
115MP0000747_muscle_weakness0.83549074
116MP0001919_abnormal_reproductive_system0.80271543
117MP0001727_abnormal_embryo_implantation0.80158045
118MP0001963_abnormal_hearing_physiology0.79543784
119MP0000427_abnormal_hair_cycle0.79482107
120MP0008058_abnormal_DNA_repair0.78552779
121MP0003119_abnormal_digestive_system0.77664224
122MP0004233_abnormal_muscle_weight0.77158764
123MP0008874_decreased_physiological_sensi0.75775357
124MP0002697_abnormal_eye_size0.74524843
125MP0003690_abnormal_glial_cell0.74330919
126MP0003693_abnormal_embryo_hatching0.74257966
127MP0004043_abnormal_pH_regulation0.74026362
128MP0002160_abnormal_reproductive_system0.71961662
129MP0003045_fibrosis0.71356988
130MP0005535_abnormal_body_temperature0.70904118
131MP0009250_abnormal_appendicular_skeleto0.70852197
132MP0000647_abnormal_sebaceous_gland0.70231037
133MP0002069_abnormal_eating/drinking_beha0.69729729
134MP0001529_abnormal_vocalization0.69325844
135MP0002111_abnormal_tail_morphology0.67921493
136MP0002210_abnormal_sex_determination0.67189883
137MP0005187_abnormal_penis_morphology0.66991452
138MP0001485_abnormal_pinna_reflex0.65831812
139MP0005551_abnormal_eye_electrophysiolog0.65654187
140MP0008872_abnormal_physiological_respon0.64369177
141MP0003861_abnormal_nervous_system0.63873390
142MP0003183_abnormal_peptide_metabolism0.60270647
143MP0004147_increased_porphyrin_level0.59211322
144MP0001145_abnormal_male_reproductive0.57488114
145MP0000653_abnormal_sex_gland0.56973354
146MP0004085_abnormal_heartbeat0.53987741
147MP0001188_hyperpigmentation0.52848379
148MP0001664_abnormal_digestion0.50634401
149MP0001943_abnormal_respiration0.50297680
150MP0003122_maternal_imprinting0.49441975
151MP0005394_taste/olfaction_phenotype0.49349329
152MP0005499_abnormal_olfactory_system0.49349329
153MP0003956_abnormal_body_size0.48849673
154MP0001177_atelectasis0.48838205
155MP0002751_abnormal_autonomic_nervous0.48663689
156MP0001270_distended_abdomen0.47644636

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.19034870
2Respiratory insufficiency due to defective ciliary clearance (HP:0200073)6.81997646
3Dynein arm defect of respiratory motile cilia (HP:0012255)6.00486489
4Absent/shortened dynein arms (HP:0200106)6.00486489
5Abnormal respiratory motile cilium physiology (HP:0012261)5.87808532
6Abnormal ciliary motility (HP:0012262)5.07395391
7Action tremor (HP:0002345)4.89542121
8Focal motor seizures (HP:0011153)4.80949405
9Progressive cerebellar ataxia (HP:0002073)4.68510288
10Abnormal respiratory epithelium morphology (HP:0012253)4.66351449
11Abnormal respiratory motile cilium morphology (HP:0005938)4.66351449
12Rhinitis (HP:0012384)4.54769502
13Pancreatic fibrosis (HP:0100732)4.48616741
14True hermaphroditism (HP:0010459)4.30052523
15Molar tooth sign on MRI (HP:0002419)4.23115357
16Abnormality of midbrain morphology (HP:0002418)4.23115357
17Focal seizures (HP:0007359)4.08852692
18Atonic seizures (HP:0010819)4.00539496
19Occipital encephalocele (HP:0002085)3.89322762
20Visual hallucinations (HP:0002367)3.87339099
21Pancreatic cysts (HP:0001737)3.65520288
22Febrile seizures (HP:0002373)3.54586692
23Gaze-evoked nystagmus (HP:0000640)3.49877944
24Chronic bronchitis (HP:0004469)3.41506585
25Infertility (HP:0000789)3.32452866
26Cystic liver disease (HP:0006706)3.30546150
27Supranuclear gaze palsy (HP:0000605)3.20380495
28Postaxial foot polydactyly (HP:0001830)3.18638352
29Termporal pattern (HP:0011008)3.15457075
30Insidious onset (HP:0003587)3.15457075
31Anencephaly (HP:0002323)3.12708228
32Epileptic encephalopathy (HP:0200134)3.05228129
33Truncal ataxia (HP:0002078)2.99486225
34Chronic hepatic failure (HP:0100626)2.89136466
35Megalencephaly (HP:0001355)2.87866555
36Aplasia/Hypoplasia of the tongue (HP:0010295)2.87405084
37Absence seizures (HP:0002121)2.86487656
38Nephrogenic diabetes insipidus (HP:0009806)2.85887159
39Abnormality of the renal medulla (HP:0100957)2.83916204
40Ulnar claw (HP:0001178)2.83781873
41Pheochromocytoma (HP:0002666)2.81411555
42Sensory axonal neuropathy (HP:0003390)2.80473954
43Abnormality of the lower motor neuron (HP:0002366)2.76529249
44Sclerocornea (HP:0000647)2.74931684
45Dysmetria (HP:0001310)2.68836956
46Abnormality of the nasal mucosa (HP:0000433)2.67630221
47Abnormality of the corticospinal tract (HP:0002492)2.60908708
48Abnormality of ocular smooth pursuit (HP:0000617)2.59935367
49Dialeptic seizures (HP:0011146)2.58068862
50Generalized tonic-clonic seizures (HP:0002069)2.58064759
51Impaired vibration sensation in the lower limbs (HP:0002166)2.55541489
52Reticulocytopenia (HP:0001896)2.52940392
53Ankle clonus (HP:0011448)2.50252468
54Bronchitis (HP:0012387)2.49291258
55Neuroendocrine neoplasm (HP:0100634)2.44937764
56Congenital hepatic fibrosis (HP:0002612)2.42193099
57Myotonia (HP:0002486)2.42074435
58Impaired smooth pursuit (HP:0007772)2.41743067
59Urinary bladder sphincter dysfunction (HP:0002839)2.39641422
60Renal dysplasia (HP:0000110)2.39153457
61Male infertility (HP:0003251)2.38148375
62Dysdiadochokinesis (HP:0002075)2.37459310
63Depression (HP:0000716)2.36933906
64Urinary urgency (HP:0000012)2.36377800
65Recurrent otitis media (HP:0000403)2.35849636
66Spastic gait (HP:0002064)2.35170308
67Scanning speech (HP:0002168)2.34884066
68Tubular atrophy (HP:0000092)2.34663326
69Postaxial hand polydactyly (HP:0001162)2.34565538
70Neurofibrillary tangles (HP:0002185)2.32952945
71Hemiparesis (HP:0001269)2.32544237
72Male pseudohermaphroditism (HP:0000037)2.32184898
73Tubulointerstitial nephritis (HP:0001970)2.31570137
74Intention tremor (HP:0002080)2.31534527
75Recurrent sinusitis (HP:0011108)2.31081524
76Abnormal eating behavior (HP:0100738)2.30818783
77Rib fusion (HP:0000902)2.30605590
78Abnormality of cells of the erythroid lineage (HP:0012130)2.29996139
79Chronic sinusitis (HP:0011109)2.28090501
80Atelectasis (HP:0100750)2.26540825
81Septo-optic dysplasia (HP:0100842)2.25368025
82Poor coordination (HP:0002370)2.25012169
83Retinal dysplasia (HP:0007973)2.24205223
84Nasal polyposis (HP:0100582)2.18711955
85Vaginal atresia (HP:0000148)2.18090956
86Preaxial hand polydactyly (HP:0001177)2.17573831
87Medial flaring of the eyebrow (HP:0010747)2.17492170
88Gait imbalance (HP:0002141)2.17357830
89Mutism (HP:0002300)2.15763338
90Anophthalmia (HP:0000528)2.14795040
91Aplasia/Hypoplasia of the spleen (HP:0010451)2.10917191
92Bronchiectasis (HP:0002110)2.10891868
93Genetic anticipation (HP:0003743)2.09941072
94Insomnia (HP:0100785)2.08872000
95Supernumerary spleens (HP:0009799)2.05377666
96Postural tremor (HP:0002174)2.03812157
97Amyotrophic lateral sclerosis (HP:0007354)2.03353821
98Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.02517181
99Degeneration of the lateral corticospinal tracts (HP:0002314)2.02517181
100Peripheral hypomyelination (HP:0007182)2.01947480
101Asplenia (HP:0001746)2.01530279
102Aplasia/Hypoplasia of the brainstem (HP:0007362)2.01245435
103Hypoplasia of the brainstem (HP:0002365)2.01245435
104Anxiety (HP:0000739)2.01222021
105Hemiplegia (HP:0002301)2.00524456
106Cerebral inclusion bodies (HP:0100314)2.00092029
107Lower limb muscle weakness (HP:0007340)2.00033793
108Holoprosencephaly (HP:0001360)1.99829321
109Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.98862007
110Progressive inability to walk (HP:0002505)1.98608355
111Postural instability (HP:0002172)1.98207292
112Congenital primary aphakia (HP:0007707)1.97570224
113Abnormal number of erythroid precursors (HP:0012131)1.97255211
114Ventricular fibrillation (HP:0001663)1.97005803
115Gait ataxia (HP:0002066)1.96798452
116Adrenal hypoplasia (HP:0000835)1.95708855
117Delusions (HP:0000746)1.91930399
118Aganglionic megacolon (HP:0002251)1.91358130
119Type II lissencephaly (HP:0007260)1.91196464
120Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90632773
121Abnormality of saccadic eye movements (HP:0000570)1.90555433
122Dysmetric saccades (HP:0000641)1.88736374
123Specific learning disability (HP:0001328)1.88687758
124Amblyopia (HP:0000646)1.88678838
125Bundle branch block (HP:0011710)1.87438978
126Broad-based gait (HP:0002136)1.87336755
127Limb dystonia (HP:0002451)1.86151531
128Genital tract atresia (HP:0001827)1.85718690
129Nephronophthisis (HP:0000090)1.85093195
130Steppage gait (HP:0003376)1.83527580
131Median cleft lip (HP:0000161)1.83388064
132Limb ataxia (HP:0002070)1.81610548
133Fetal akinesia sequence (HP:0001989)1.81250383
134Status epilepticus (HP:0002133)1.80382894
135Morphological abnormality of the pyramidal tract (HP:0002062)1.79582848
136Neuronal loss in central nervous system (HP:0002529)1.78886255
137Impaired vibratory sensation (HP:0002495)1.78088587
138Oculomotor apraxia (HP:0000657)1.77860416
139Abnormality of DNA repair (HP:0003254)1.76829922
140Anosmia (HP:0000458)1.76468576
141Diplopia (HP:0000651)1.75652497
142Abnormality of binocular vision (HP:0011514)1.75652497
143Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.73907889
144Broad foot (HP:0001769)1.73529994
145Hammertoe (HP:0001765)1.72573900
146Poor eye contact (HP:0000817)1.72479007
147Bell-shaped thorax (HP:0001591)1.71813900
148Acute necrotizing encephalopathy (HP:0006965)1.70961475
149Maternal diabetes (HP:0009800)1.69967942
150Dandy-Walker malformation (HP:0001305)1.69583011
151Narrow forehead (HP:0000341)1.69440813
152Multicystic kidney dysplasia (HP:0000003)1.68195770
153Short femoral neck (HP:0100864)1.66766595
154Depressed nasal ridge (HP:0000457)1.65170036
155Aplasia/Hypoplasia of the lens (HP:0008063)1.61942606
156Abnormality of the aortic arch (HP:0012303)1.61872922
157Furrowed tongue (HP:0000221)1.61848737
158Tubulointerstitial abnormality (HP:0001969)1.61733585
159Hip dysplasia (HP:0001385)1.59219591
160Optic nerve coloboma (HP:0000588)1.56334355
161Decreased testicular size (HP:0008734)1.56122245
162Prominent nasal bridge (HP:0000426)1.55542811
163Oligodactyly (HP:0012165)1.55516475
164Optic nerve hypoplasia (HP:0000609)1.54041322
165Abnormal rod and cone electroretinograms (HP:0008323)1.53093539
166Abnormal mitochondria in muscle tissue (HP:0008316)1.51313010
167Bile duct proliferation (HP:0001408)1.49229141
168Abnormal biliary tract physiology (HP:0012439)1.49229141
169Polydipsia (HP:0001959)1.48028621
170Abnormal drinking behavior (HP:0030082)1.48028621
171Renal salt wasting (HP:0000127)1.47256962
172Abnormality of the renal cortex (HP:0011035)1.46096233
173Retinitis pigmentosa (HP:0000510)1.44911155
174Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.43464738
175Acute encephalopathy (HP:0006846)1.43325709
176Abnormality of abdominal situs (HP:0011620)1.42946590
177Abdominal situs inversus (HP:0003363)1.42946590
178Macrocytic anemia (HP:0001972)1.42309306
179Absent rod-and cone-mediated responses on ERG (HP:0007688)1.41107269
180Broad distal phalanx of finger (HP:0009836)1.40154351

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK155.82061230
2MAP3K94.25449742
3NTRK33.74620601
4PRKD33.16592174
5KSR23.07422525
6LMTK22.92041034
7PDK42.64512448
8PDK32.64512448
9MINK12.61480991
10MAP3K42.49344575
11GRK52.44120480
12EPHA42.31532823
13ARAF2.27140042
14DYRK22.20138906
15STK162.19789159
16PAK62.17345788
17AURKA2.09735283
18TLK12.06793871
19NTRK22.06776519
20NTRK11.95980629
21CDC71.94473797
22MAP3K111.93126732
23BCR1.92820408
24MAP4K21.90923305
25STK381.89319991
26LATS21.86984135
27BCKDK1.84928084
28PNCK1.80902111
29PLK41.76274065
30MAP2K71.75835657
31ZAK1.74713934
32MAP3K21.74701487
33WNK31.73415587
34DAPK21.71389748
35EPHB21.69765065
36NME11.69312219
37INSRR1.66070276
38TESK11.59875287
39MAP2K41.57534250
40CAMKK11.56445208
41NEK21.55489847
42EPHA21.53595394
43LRRK21.51294523
44PTK2B1.48068108
45CAMKK21.40317341
46MAPK131.38760675
47STK391.38195232
48PLK11.35420087
49TTK1.35203840
50MAP3K121.34822973
51WNK11.31739945
52PDK21.30875952
53MARK11.30185907
54PHKG21.30163316
55PHKG11.30163316
56RET1.29471503
57CHEK21.28630878
58PIM21.23575743
59PRKCI1.21325753
60CCNB11.20002459
61CDK51.17756506
62TAOK11.17522216
63DMPK1.16502223
64MST41.15304936
65SGK4941.14677347
66SGK2231.14677347
67GRK11.12904631
68TYRO31.12498629
69ICK1.12126146
70PRKCG1.09729890
71CAMK1D1.09708438
72DYRK31.08967815
73ADRBK21.06911702
74AURKB1.01162454
75RIPK40.98891629
76MAPKAPK50.98671206
77CDK140.97131670
78VRK20.96186002
79ATR0.95886419
80PINK10.94988240
81DYRK1B0.94740392
82MAP3K130.93951563
83CDK150.93116072
84CDK180.92555991
85PLK20.90645265
86SGK20.90550341
87PDK10.88694376
88KSR10.88499515
89WNK40.87934131
90UHMK10.86429800
91CDK190.85553396
92LIMK10.84196808
93MUSK0.81935586
94CDK11A0.80209505
95BRAF0.79669942
96MOS0.78603394
97RIPK10.75568157
98VRK10.75235355
99PDPK10.75129306
100WEE10.73355624
101TIE10.72817748
102CSNK1G30.71837770
103SGK30.71765755
104CDK80.71488550
105SIK20.69384932
106MAP3K10.69136773
107TNIK0.67457570
108CAMK2A0.65786035
109RAF10.64259883
110BMPR1B0.63824409
111DAPK10.62182354
112PRKCH0.61605772
113RPS6KA50.59835102
114MAP2K10.57036432
115OXSR10.56643366
116AKT20.56198810
117STK240.55269481
118PAK30.54100548
119PRKACA0.53641456
120CSNK1A1L0.53084424
121PRPF4B0.52943439
122MARK20.51588228
123ROCK20.51229941
124CAMK10.49147050
125CSNK1G10.48689407
126STK110.47919387
127TNK20.47624304
128CASK0.45868557
129CDC42BPA0.44130976
130CSNK1E0.43661301
131PRKCQ0.43366417
132NUAK10.42982816
133RPS6KA60.42790177
134MAPKAPK30.42175556
135CSNK1A10.42158707
136BUB10.41594980
137MKNK20.40206062
138CAMK2D0.39566303
139NEK10.38387990
140CAMK2B0.37579682
141FES0.37526890
142ATM0.37035165
143CAMK2G0.36770535
144CAMK1G0.36499185
145DAPK30.36152921
146BRSK10.36119389
147CHEK10.35962956
148STK30.35319925
149PRKCZ0.35253653
150CSNK1G20.35142679
151MAPK100.34895209
152RPS6KA20.34681580
153SGK10.33918813
154TRIB30.32657484
155RPS6KA30.32167722
156NEK60.31030872
157ROCK10.30962612
158PTK20.30858839
159FER0.30682798

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.10269425
2Synaptic vesicle cycle_Homo sapiens_hsa047213.43459674
3Nicotine addiction_Homo sapiens_hsa050333.06338790
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.01754808
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.53123575
6Long-term potentiation_Homo sapiens_hsa047202.51413446
7Glutamatergic synapse_Homo sapiens_hsa047242.36787471
8Circadian entrainment_Homo sapiens_hsa047132.27695913
9Homologous recombination_Homo sapiens_hsa034402.27632456
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26678771
11Olfactory transduction_Homo sapiens_hsa047402.20692310
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.19290093
13Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.17344430
14Salivary secretion_Homo sapiens_hsa049702.07271386
15Amphetamine addiction_Homo sapiens_hsa050312.07144506
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.03915783
17Fanconi anemia pathway_Homo sapiens_hsa034602.01909097
18Taste transduction_Homo sapiens_hsa047421.99745489
19GABAergic synapse_Homo sapiens_hsa047271.98734182
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.95946226
21Basal cell carcinoma_Homo sapiens_hsa052171.94125585
22Dopaminergic synapse_Homo sapiens_hsa047281.88783909
23Linoleic acid metabolism_Homo sapiens_hsa005911.85513868
24Insulin secretion_Homo sapiens_hsa049111.85510341
25Morphine addiction_Homo sapiens_hsa050321.80753106
26Gastric acid secretion_Homo sapiens_hsa049711.80580525
27Collecting duct acid secretion_Homo sapiens_hsa049661.79685482
28Steroid biosynthesis_Homo sapiens_hsa001001.78943812
29Long-term depression_Homo sapiens_hsa047301.77107275
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.73770467
31Dorso-ventral axis formation_Homo sapiens_hsa043201.72299152
32Chemical carcinogenesis_Homo sapiens_hsa052041.70600899
33Nucleotide excision repair_Homo sapiens_hsa034201.70175278
34Base excision repair_Homo sapiens_hsa034101.69992892
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.68663659
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.63208729
37Cholinergic synapse_Homo sapiens_hsa047251.60822896
38Phototransduction_Homo sapiens_hsa047441.59090817
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58520454
40Cardiac muscle contraction_Homo sapiens_hsa042601.58440509
41Protein export_Homo sapiens_hsa030601.58247577
42Phenylalanine metabolism_Homo sapiens_hsa003601.54888437
43Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.54722741
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.53162107
45Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.49823098
46RNA polymerase_Homo sapiens_hsa030201.49479535
47GnRH signaling pathway_Homo sapiens_hsa049121.46878594
48Tyrosine metabolism_Homo sapiens_hsa003501.44209159
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43485707
50Fatty acid biosynthesis_Homo sapiens_hsa000611.41548948
51Mismatch repair_Homo sapiens_hsa034301.36583243
52Oxytocin signaling pathway_Homo sapiens_hsa049211.36544411
53Pyrimidine metabolism_Homo sapiens_hsa002401.35988488
54Renin secretion_Homo sapiens_hsa049241.35917493
55Glutathione metabolism_Homo sapiens_hsa004801.35303075
56Phosphatidylinositol signaling system_Homo sapiens_hsa040701.34151149
57Oocyte meiosis_Homo sapiens_hsa041141.33688542
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.33192654
59Serotonergic synapse_Homo sapiens_hsa047261.32813366
60Sulfur relay system_Homo sapiens_hsa041221.31535065
61Calcium signaling pathway_Homo sapiens_hsa040201.29260235
62Estrogen signaling pathway_Homo sapiens_hsa049151.28054357
63Gap junction_Homo sapiens_hsa045401.24397701
64Notch signaling pathway_Homo sapiens_hsa043301.21271108
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.20630597
66Hippo signaling pathway_Homo sapiens_hsa043901.18621792
67Histidine metabolism_Homo sapiens_hsa003401.17827695
68Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.16944521
69Cocaine addiction_Homo sapiens_hsa050301.15681106
70Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.10646362
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.10075742
72Basal transcription factors_Homo sapiens_hsa030221.09463729
73DNA replication_Homo sapiens_hsa030301.09223430
74Butanoate metabolism_Homo sapiens_hsa006501.09146173
75Oxidative phosphorylation_Homo sapiens_hsa001901.07143959
76Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07103918
77cAMP signaling pathway_Homo sapiens_hsa040241.06297668
78Peroxisome_Homo sapiens_hsa041461.05168191
79Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04835230
80Glioma_Homo sapiens_hsa052141.04449825
81beta-Alanine metabolism_Homo sapiens_hsa004101.02561828
82Huntingtons disease_Homo sapiens_hsa050160.99473022
83Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97072833
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96187656
85Thyroid hormone synthesis_Homo sapiens_hsa049180.96043877
86Type II diabetes mellitus_Homo sapiens_hsa049300.95805275
87Alzheimers disease_Homo sapiens_hsa050100.94730914
88Retinol metabolism_Homo sapiens_hsa008300.91868030
89VEGF signaling pathway_Homo sapiens_hsa043700.91288229
90ErbB signaling pathway_Homo sapiens_hsa040120.91229985
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.91076309
92Glucagon signaling pathway_Homo sapiens_hsa049220.90930437
93Pancreatic secretion_Homo sapiens_hsa049720.90035768
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89586737
95Melanogenesis_Homo sapiens_hsa049160.89038714
96Vascular smooth muscle contraction_Homo sapiens_hsa042700.88608871
97Propanoate metabolism_Homo sapiens_hsa006400.86932118
98Vitamin B6 metabolism_Homo sapiens_hsa007500.86268324
99Vibrio cholerae infection_Homo sapiens_hsa051100.85967596
100Parkinsons disease_Homo sapiens_hsa050120.85196520
101Metabolic pathways_Homo sapiens_hsa011000.84586136
102Axon guidance_Homo sapiens_hsa043600.83908349
103Arachidonic acid metabolism_Homo sapiens_hsa005900.83350495
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.75406573
105Tryptophan metabolism_Homo sapiens_hsa003800.74509465
106Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.73166833
107Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72058599
108Choline metabolism in cancer_Homo sapiens_hsa052310.71982295
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.71831331
110Endocytosis_Homo sapiens_hsa041440.70677028
111RNA degradation_Homo sapiens_hsa030180.70632507
112Purine metabolism_Homo sapiens_hsa002300.70579429
113Folate biosynthesis_Homo sapiens_hsa007900.68155440
114Drug metabolism - other enzymes_Homo sapiens_hsa009830.67699796
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.67368429
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.67014564
117Spliceosome_Homo sapiens_hsa030400.66955211
118Fatty acid degradation_Homo sapiens_hsa000710.66684339
119Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66071547
120One carbon pool by folate_Homo sapiens_hsa006700.65971440
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65081134
122Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64446379
123Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62548641
124Inositol phosphate metabolism_Homo sapiens_hsa005620.62363892
125Caffeine metabolism_Homo sapiens_hsa002320.62081967
126p53 signaling pathway_Homo sapiens_hsa041150.61676103
127Steroid hormone biosynthesis_Homo sapiens_hsa001400.61650095
128MAPK signaling pathway_Homo sapiens_hsa040100.61437296
129Tight junction_Homo sapiens_hsa045300.61067414
130Mineral absorption_Homo sapiens_hsa049780.60728491
131Glycerophospholipid metabolism_Homo sapiens_hsa005640.60121428
1322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58501458
133Arginine and proline metabolism_Homo sapiens_hsa003300.57911885
134Proteasome_Homo sapiens_hsa030500.57449101
135Pyruvate metabolism_Homo sapiens_hsa006200.53093559
136Insulin signaling pathway_Homo sapiens_hsa049100.52947482
137Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52348670
138mTOR signaling pathway_Homo sapiens_hsa041500.52213841
139Circadian rhythm_Homo sapiens_hsa047100.51995549
140Ether lipid metabolism_Homo sapiens_hsa005650.51678889
141Bile secretion_Homo sapiens_hsa049760.50646505
142Biosynthesis of amino acids_Homo sapiens_hsa012300.50614604
143Prolactin signaling pathway_Homo sapiens_hsa049170.49425816
144Ovarian steroidogenesis_Homo sapiens_hsa049130.49011504
145Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48615419
146Thyroid hormone signaling pathway_Homo sapiens_hsa049190.48611435
147Alcoholism_Homo sapiens_hsa050340.46701178
148Fatty acid elongation_Homo sapiens_hsa000620.46493853
149Ras signaling pathway_Homo sapiens_hsa040140.45841565
150Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45451133
151RNA transport_Homo sapiens_hsa030130.44786691
152Central carbon metabolism in cancer_Homo sapiens_hsa052300.43157744
153Endometrial cancer_Homo sapiens_hsa052130.42690121
154Rap1 signaling pathway_Homo sapiens_hsa040150.41228413
155Cysteine and methionine metabolism_Homo sapiens_hsa002700.41160089
156Renal cell carcinoma_Homo sapiens_hsa052110.40829852
157Selenocompound metabolism_Homo sapiens_hsa004500.40433766
158Dilated cardiomyopathy_Homo sapiens_hsa054140.38813047
159Fat digestion and absorption_Homo sapiens_hsa049750.38201631
160Cell cycle_Homo sapiens_hsa041100.37088780
161Hedgehog signaling pathway_Homo sapiens_hsa043400.36775865
162Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34597896
163Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.34072446
164Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.32831503
165Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31970425
166Glycerolipid metabolism_Homo sapiens_hsa005610.31895370
167Wnt signaling pathway_Homo sapiens_hsa043100.31380144
168SNARE interactions in vesicular transport_Homo sapiens_hsa041300.30762984
169Nitrogen metabolism_Homo sapiens_hsa009100.30735774
170Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29758397
171Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.29300467
172Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29123169

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »