CCDC77

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)4.82301034
2kinetochore assembly (GO:0051382)4.53932810
3meiotic chromosome segregation (GO:0045132)4.22987654
4CENP-A containing nucleosome assembly (GO:0034080)4.18239787
5chromatin remodeling at centromere (GO:0031055)4.05530161
6microtubule depolymerization (GO:0007019)3.92592674
7negative regulation of DNA-dependent DNA replication (GO:2000104)3.91696312
8protein K6-linked ubiquitination (GO:0085020)3.83944061
9regulation of centriole replication (GO:0046599)3.80414363
10regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.66427551
11mitotic metaphase plate congression (GO:0007080)3.61271724
12DNA strand renaturation (GO:0000733)3.61220376
13synapsis (GO:0007129)3.56600208
14telomere maintenance via semi-conservative replication (GO:0032201)3.56195374
15establishment of integrated proviral latency (GO:0075713)3.54394190
16maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.54103371
17telomere maintenance via recombination (GO:0000722)3.50065161
18regulation of nuclear cell cycle DNA replication (GO:0033262)3.46159320
19DNA replication-independent nucleosome organization (GO:0034724)3.44683402
20DNA replication-independent nucleosome assembly (GO:0006336)3.44683402
21mismatch repair (GO:0006298)3.41013622
22DNA replication initiation (GO:0006270)3.40554367
23mitotic recombination (GO:0006312)3.40126418
24metaphase plate congression (GO:0051310)3.38515691
25DNA synthesis involved in DNA repair (GO:0000731)3.38176363
26DNA replication-dependent nucleosome assembly (GO:0006335)3.33189176
27DNA replication-dependent nucleosome organization (GO:0034723)3.33189176
28regulation of chromosome segregation (GO:0051983)3.32915361
29DNA ligation (GO:0006266)3.32347123
30somatic diversification of immune receptors via somatic mutation (GO:0002566)3.32337159
31somatic hypermutation of immunoglobulin genes (GO:0016446)3.32337159
32resolution of meiotic recombination intermediates (GO:0000712)3.32000133
33histone exchange (GO:0043486)3.31351451
34regulation of meiosis I (GO:0060631)3.29440348
35replication fork processing (GO:0031297)3.24816185
36regulation of DNA endoreduplication (GO:0032875)3.18736102
37protein localization to chromosome (GO:0034502)3.17656014
38non-recombinational repair (GO:0000726)3.17154205
39double-strand break repair via nonhomologous end joining (GO:0006303)3.17154205
40DNA replication checkpoint (GO:0000076)3.15392338
41establishment of chromosome localization (GO:0051303)3.15315779
42centriole replication (GO:0007099)3.14988424
43centriole assembly (GO:0098534)3.14179991
44exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13058732
45DNA strand elongation involved in DNA replication (GO:0006271)3.12752250
46regulation of mitotic spindle checkpoint (GO:1903504)3.11925888
47regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.11925888
48histone H2A acetylation (GO:0043968)3.11917110
49intra-S DNA damage checkpoint (GO:0031573)3.11527447
50chromosome condensation (GO:0030261)3.10873048
51positive regulation of chromosome segregation (GO:0051984)3.09616637
52regulation of centrosome cycle (GO:0046605)3.07761953
53telomere maintenance via telomere lengthening (GO:0010833)3.07179530
54DNA strand elongation (GO:0022616)3.07086047
55mitotic nuclear envelope disassembly (GO:0007077)3.06135763
56nuclear pore complex assembly (GO:0051292)3.05510552
57nuclear pore organization (GO:0006999)3.05399789
58nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.04000455
59attachment of spindle microtubules to kinetochore (GO:0008608)3.00821715
60DNA double-strand break processing (GO:0000729)2.99519962
61positive regulation of DNA-dependent DNA replication (GO:2000105)2.99178173
62ribosomal small subunit assembly (GO:0000028)2.98465322
63response to pheromone (GO:0019236)2.98349857
64DNA topological change (GO:0006265)2.95539700
65DNA damage response, detection of DNA damage (GO:0042769)2.94529939
66negative regulation of DNA recombination (GO:0045910)2.94469720
67proteasome assembly (GO:0043248)2.93655596
68piRNA metabolic process (GO:0034587)2.93434487
69meiotic cell cycle (GO:0051321)2.92693413
70single strand break repair (GO:0000012)2.92267956
71nucleotide-excision repair, DNA gap filling (GO:0006297)2.90403156
72mitotic G2/M transition checkpoint (GO:0044818)2.89574500
73regulation of helicase activity (GO:0051095)2.88996979
74spindle checkpoint (GO:0031577)2.87466890
75DNA packaging (GO:0006323)2.87410881
76chromatin assembly or disassembly (GO:0006333)2.86526988
77anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.83245043
78regulation of double-strand break repair via homologous recombination (GO:0010569)2.83107929
79telomere maintenance (GO:0000723)2.81369269
80protein localization to chromosome, centromeric region (GO:0071459)2.81291058
81telomere organization (GO:0032200)2.77791645
82regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.77307901
83protein localization to kinetochore (GO:0034501)2.76185612
84transcription elongation from RNA polymerase I promoter (GO:0006362)2.75798940
85mitotic chromosome condensation (GO:0007076)2.75280350
86ribosomal large subunit biogenesis (GO:0042273)2.73805299
87DNA integration (GO:0015074)2.73371335
88mitotic sister chromatid segregation (GO:0000070)2.71794554
89regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.67651361
90ATP-dependent chromatin remodeling (GO:0043044)2.66111123
91pore complex assembly (GO:0046931)2.65890758
92rRNA modification (GO:0000154)2.65113184
93regulation of DNA-dependent DNA replication (GO:0090329)2.64979853
94regulation of mitotic metaphase/anaphase transition (GO:0030071)2.64449299
95DNA catabolic process, exonucleolytic (GO:0000738)2.64438055
96maturation of SSU-rRNA (GO:0030490)2.63670077
97mitotic spindle checkpoint (GO:0071174)2.63045437
98termination of RNA polymerase I transcription (GO:0006363)2.62204709
99regulation of spindle organization (GO:0090224)2.61687183
100transcription-coupled nucleotide-excision repair (GO:0006283)2.61658646
101negative regulation of mitotic sister chromatid separation (GO:2000816)2.60447785
102negative regulation of mitotic sister chromatid segregation (GO:0033048)2.60447785
103negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.60447785
104negative regulation of sister chromatid segregation (GO:0033046)2.60447785
105spindle assembly checkpoint (GO:0071173)2.59491496
106regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.58875545
107rRNA methylation (GO:0031167)2.58320389
108daunorubicin metabolic process (GO:0044597)2.57861849
109polyketide metabolic process (GO:0030638)2.57861849
110doxorubicin metabolic process (GO:0044598)2.57861849
111negative regulation of chromosome segregation (GO:0051985)2.57705165
112reciprocal meiotic recombination (GO:0007131)2.57011017
113reciprocal DNA recombination (GO:0035825)2.57011017
114regulation of sister chromatid segregation (GO:0033045)2.56722169
115regulation of mitotic sister chromatid separation (GO:0010965)2.56722169
116regulation of mitotic sister chromatid segregation (GO:0033047)2.56722169
117chromosome segregation (GO:0007059)2.56233667
118mitotic sister chromatid cohesion (GO:0007064)2.54863842
119recombinational repair (GO:0000725)2.54726192
120positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.53880033
121positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.53880033
122positive regulation of mitotic sister chromatid separation (GO:1901970)2.53880033
123negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.53352383
124replicative senescence (GO:0090399)2.52587456
125microtubule polymerization or depolymerization (GO:0031109)2.52261909
126sister chromatid segregation (GO:0000819)2.51466182
127DNA recombination (GO:0006310)2.51157668
128regulation of spindle checkpoint (GO:0090231)2.50593834
129DNA-dependent DNA replication (GO:0006261)2.50047112
130viral mRNA export from host cell nucleus (GO:0046784)2.49255395
131mitotic spindle assembly checkpoint (GO:0007094)2.48652044
132DNA replication (GO:0006260)2.48181646

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.55130888
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.23404816
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.05054937
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.49181069
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.40542569
6MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.91131678
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83676407
8TP63_19390658_ChIP-ChIP_HaCaT_Human2.74337057
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.50598519
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.36089892
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.31087589
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.21312157
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.15381470
14* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.15267833
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.11924649
16PCGF2_27294783_Chip-Seq_ESCs_Mouse2.01235831
17FLI1_27457419_Chip-Seq_LIVER_Mouse2.00645094
18ZNF274_21170338_ChIP-Seq_K562_Hela1.99476917
19GABP_17652178_ChIP-ChIP_JURKAT_Human1.97190646
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.94098745
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.92302079
22ELK1_19687146_ChIP-ChIP_HELA_Human1.92246628
23E2F1_21310950_ChIP-Seq_MCF-7_Human1.91474746
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.86038114
25MYC_19030024_ChIP-ChIP_MESCs_Mouse1.83599981
26HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.78493857
27* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.76545306
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76241910
29* VDR_23849224_ChIP-Seq_CD4+_Human1.75869904
30YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73024519
31* FOXP3_21729870_ChIP-Seq_TREG_Human1.72065763
32FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.70313667
33PCGF2_27294783_Chip-Seq_NPCs_Mouse1.62796562
34* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.61664751
35POU5F1_16153702_ChIP-ChIP_HESCs_Human1.59961621
36EWS_26573619_Chip-Seq_HEK293_Human1.58624812
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.58033018
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.56280330
39MYC_18358816_ChIP-ChIP_MESCs_Mouse1.53484135
40FUS_26573619_Chip-Seq_HEK293_Human1.52646705
41NFE2_27457419_Chip-Seq_LIVER_Mouse1.52513720
42SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52205782
43GABP_19822575_ChIP-Seq_HepG2_Human1.50996536
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.50875404
45SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.50552965
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.47879142
47* ETS1_20019798_ChIP-Seq_JURKAT_Human1.46786782
48NELFA_20434984_ChIP-Seq_ESCs_Mouse1.39741982
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.38801902
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.35967847
51CREB1_15753290_ChIP-ChIP_HEK293T_Human1.35474599
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.34416833
53NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.33712629
54IRF1_19129219_ChIP-ChIP_H3396_Human1.33318955
55IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.33153805
56VDR_22108803_ChIP-Seq_LS180_Human1.30035579
57SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27203731
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.26998009
59MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26968353
60* PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.26603461
61TTF2_22483619_ChIP-Seq_HELA_Human1.26512714
62POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25486951
63YY1_21170310_ChIP-Seq_MESCs_Mouse1.23571683
64SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.20424217
65MYC_18940864_ChIP-ChIP_HL60_Human1.18283486
66* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18255323
67FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.16615665
68* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16334815
69EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.16184733
70AR_21909140_ChIP-Seq_LNCAP_Human1.14665812
71IGF1R_20145208_ChIP-Seq_DFB_Human1.12743649
72STAT3_18555785_Chip-Seq_ESCs_Mouse1.12190747
73NANOG_16153702_ChIP-ChIP_HESCs_Human1.12029731
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11312910
75EZH2_22144423_ChIP-Seq_EOC_Human1.10526050
76POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10299318
77SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10287276
78CIITA_25753668_ChIP-Seq_RAJI_Human1.09757388
79TAF15_26573619_Chip-Seq_HEK293_Human1.09124481
80* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.08517495
81P300_19829295_ChIP-Seq_ESCs_Human1.07981375
82THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06283699
83E2F1_18555785_ChIP-Seq_MESCs_Mouse1.05993540
84SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.05089061
85EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05062164
86PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03997628
87NMYC_18555785_Chip-Seq_ESCs_Mouse1.03928983
88E2F1_18555785_Chip-Seq_ESCs_Mouse1.03807085
89EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.03704815
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.03099410
91* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.02816650
92TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02679253
93P53_22387025_ChIP-Seq_ESCs_Mouse1.02297735
94DCP1A_22483619_ChIP-Seq_HELA_Human1.01760972
95HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01120627
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.00849527
97* KDM5A_27292631_Chip-Seq_BREAST_Human1.00611642
98ZFX_18555785_Chip-Seq_ESCs_Mouse1.00397858
99KAP1_22055183_ChIP-Seq_ESCs_Mouse0.99999028
100EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99631225
101P300_18555785_Chip-Seq_ESCs_Mouse0.99225256
102OCT4_18555785_Chip-Seq_ESCs_Mouse0.99203659
103RUNX1_27457419_Chip-Seq_LIVER_Mouse0.97700027
104PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97156001
105BP1_19119308_ChIP-ChIP_Hs578T_Human0.96585814
106ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96528848
107* XRN2_22483619_ChIP-Seq_HELA_Human0.96354926
108CTBP2_25329375_ChIP-Seq_LNCAP_Human0.96223745
109TP53_22573176_ChIP-Seq_HFKS_Human0.92440704
110SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.92339600
111KLF4_18555785_Chip-Seq_ESCs_Mouse0.92086913
112FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91440256
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91208450
114LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90896750
115IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.90782602
116CBP_20019798_ChIP-Seq_JUKART_Human0.90782602
117CMYC_18555785_Chip-Seq_ESCs_Mouse0.89026711
118GBX2_23144817_ChIP-Seq_PC3_Human0.88686771
119GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88184338
120CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87420665
121GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87160292
122SOX2_18555785_Chip-Seq_ESCs_Mouse0.86688760
123BMI1_23680149_ChIP-Seq_NPCS_Mouse0.86224373
124SOX2_16153702_ChIP-ChIP_HESCs_Human0.85755691
125UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84126554
126ZFX_18555785_ChIP-Seq_MESCs_Mouse0.82771168
127CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.79563725
128POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.78764032
129TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78764032
130DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.78757500
131GATA1_26923725_Chip-Seq_HPCs_Mouse0.76035013
132SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.74640568
133NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.74352281
134CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.73285674

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.03061551
2MP0010094_abnormal_chromosome_stability3.69784842
3MP0008058_abnormal_DNA_repair3.59309158
4MP0003693_abnormal_embryo_hatching3.49125578
5MP0003111_abnormal_nucleus_morphology3.40291842
6MP0006292_abnormal_olfactory_placode2.93008617
7MP0003136_yellow_coat_color2.76652096
8MP0003077_abnormal_cell_cycle2.72442455
9MP0000566_synostosis2.64916476
10MP0001188_hyperpigmentation2.40500545
11MP0002102_abnormal_ear_morphology2.29823290
12MP0008877_abnormal_DNA_methylation2.07915782
13MP0008007_abnormal_cellular_replicative1.99272211
14MP0004381_abnormal_hair_follicle1.95049553
15MP0004957_abnormal_blastocyst_morpholog1.91482280
16MP0008932_abnormal_embryonic_tissue1.88625352
17MP0002396_abnormal_hematopoietic_system1.86461211
18MP0005174_abnormal_tail_pigmentation1.85409008
19MP0005075_abnormal_melanosome_morpholog1.83065460
20MP0002938_white_spotting1.80787210
21MP0000372_irregular_coat_pigmentation1.78526270
22MP0003786_premature_aging1.71372730
23MP0002132_abnormal_respiratory_system1.66469085
24MP0005171_absent_coat_pigmentation1.62876111
25MP0002163_abnormal_gland_morphology1.61926311
26MP0000383_abnormal_hair_follicle1.56451282
27MP0000015_abnormal_ear_pigmentation1.54945125
28MP0003941_abnormal_skin_development1.53663516
29MP0002095_abnormal_skin_pigmentation1.52007006
30MP0005451_abnormal_body_composition1.50202656
31MP0001529_abnormal_vocalization1.48022239
32MP0009697_abnormal_copulation1.46822940
33MP0001293_anophthalmia1.40305194
34MP0002277_abnormal_respiratory_mucosa1.39908071
35MP0000569_abnormal_digit_pigmentation1.37620328
36MP0000490_abnormal_crypts_of1.36698268
37MP0003698_abnormal_male_reproductive1.34887288
38MP0003787_abnormal_imprinting1.34639465
39MP0006072_abnormal_retinal_apoptosis1.33169575
40MP0001730_embryonic_growth_arrest1.30782058
41MP0005410_abnormal_fertilization1.30441218
42MP0003763_abnormal_thymus_physiology1.29846489
43MP0002210_abnormal_sex_determination1.29440360
44MP0003122_maternal_imprinting1.25711706
45MP0002084_abnormal_developmental_patter1.24166253
46MP0003121_genomic_imprinting1.23276900
47MP0001697_abnormal_embryo_size1.22774005
48MP0000631_abnormal_neuroendocrine_gland1.22632499
49MP0005409_darkened_coat_color1.22546768
50MP0001986_abnormal_taste_sensitivity1.20905093
51MP0002234_abnormal_pharynx_morphology1.20187532
52MP0006035_abnormal_mitochondrial_morpho1.19824528
53MP0003718_maternal_effect1.18491040
54MP0002160_abnormal_reproductive_system1.16549162
55MP0003937_abnormal_limbs/digits/tail_de1.15854655
56MP0003890_abnormal_embryonic-extraembry1.13083624
57MP0005379_endocrine/exocrine_gland_phen1.12742409
58MP0003880_abnormal_central_pattern1.12181010
59MP0009379_abnormal_foot_pigmentation1.10728420
60MP0008995_early_reproductive_senescence1.10319731
61MP0003119_abnormal_digestive_system1.08972274
62MP0003315_abnormal_perineum_morphology1.08147883
63MP0008789_abnormal_olfactory_epithelium1.07019551
64MP0005395_other_phenotype1.06290743
65MP0005389_reproductive_system_phenotype1.02177354
66MP0004808_abnormal_hematopoietic_stem1.01165497
67MP0001119_abnormal_female_reproductive0.99577319
68MP0003950_abnormal_plasma_membrane0.99202400
69MP0002161_abnormal_fertility/fecundity0.98489388
70MP0005253_abnormal_eye_physiology0.98449106
71MP0002697_abnormal_eye_size0.98423198
72MP0005551_abnormal_eye_electrophysiolog0.98292502
73MP0010307_abnormal_tumor_latency0.97760017
74MP0000350_abnormal_cell_proliferation0.97429695
75MP0002075_abnormal_coat/hair_pigmentati0.97331025
76MP0001929_abnormal_gametogenesis0.96954849
77MP0002009_preneoplasia0.96134488
78MP0001186_pigmentation_phenotype0.94267800
79MP0001984_abnormal_olfaction0.93338287
80MP0001145_abnormal_male_reproductive0.92479503
81MP0000049_abnormal_middle_ear0.91218572
82MP0005645_abnormal_hypothalamus_physiol0.91201094
83MP0000653_abnormal_sex_gland0.89563036
84MP0003938_abnormal_ear_development0.89009085
85MP0002080_prenatal_lethality0.87782621
86MP0001485_abnormal_pinna_reflex0.87779476
87MP0002249_abnormal_larynx_morphology0.87145914
88MP0000313_abnormal_cell_death0.86712477
89MP0006276_abnormal_autonomic_nervous0.85542031
90MP0004197_abnormal_fetal_growth/weight/0.85179077
91MP0004147_increased_porphyrin_level0.84482440
92MP0003984_embryonic_growth_retardation0.84406054
93MP0001286_abnormal_eye_development0.84291658
94MP0003699_abnormal_female_reproductive0.83984033
95MP0001346_abnormal_lacrimal_gland0.83034711
96MP0003186_abnormal_redox_activity0.83024687
97MP0002088_abnormal_embryonic_growth/wei0.82900700
98MP0003861_abnormal_nervous_system0.82833524
99MP0000358_abnormal_cell_content/0.82579697
100MP0003195_calcinosis0.81866542
101MP0001919_abnormal_reproductive_system0.80878226
102MP0000703_abnormal_thymus_morphology0.80821999
103MP0005377_hearing/vestibular/ear_phenot0.80120029
104MP0003878_abnormal_ear_physiology0.80120029
105MP0006036_abnormal_mitochondrial_physio0.79742539
106MP0000432_abnormal_head_morphology0.79573016
107MP0004133_heterotaxia0.78615838
108MP0002085_abnormal_embryonic_tissue0.78434432
109MP0002398_abnormal_bone_marrow0.78344080
110MP0000647_abnormal_sebaceous_gland0.77378656
111MP0002177_abnormal_outer_ear0.77041685
112MP0002019_abnormal_tumor_incidence0.76966675
113MP0008260_abnormal_autophagy0.76959870
114MP0002111_abnormal_tail_morphology0.76781353
115MP0002751_abnormal_autonomic_nervous0.76223239
116MP0003567_abnormal_fetal_cardiomyocyte0.75668608
117MP0001672_abnormal_embryogenesis/_devel0.75526903
118MP0005380_embryogenesis_phenotype0.75526903
119MP0000026_abnormal_inner_ear0.75097690
120MP0002653_abnormal_ependyma_morphology0.74443951
121MP0010030_abnormal_orbit_morphology0.74272622
122MP0000428_abnormal_craniofacial_morphol0.73902193
123MP0005391_vision/eye_phenotype0.72538785
124MP0002233_abnormal_nose_morphology0.71012643
125MP0005671_abnormal_response_to0.70557414
126MP0001835_abnormal_antigen_presentation0.70221896
127MP0003123_paternal_imprinting0.69206905
128MP0002092_abnormal_eye_morphology0.68969077
129MP0003755_abnormal_palate_morphology0.68006477
130MP0005646_abnormal_pituitary_gland0.67698476
131MP0005394_taste/olfaction_phenotype0.67259506
132MP0005499_abnormal_olfactory_system0.67259506
133MP0000516_abnormal_urinary_system0.66924762
134MP0005367_renal/urinary_system_phenotyp0.66924762
135MP0000427_abnormal_hair_cycle0.66362732
136MP0001764_abnormal_homeostasis0.66133771
137MP0000371_diluted_coat_color0.65988380
138MP0009333_abnormal_splenocyte_physiolog0.65599997
139MP0002736_abnormal_nociception_after0.62794265
140MP0001324_abnormal_eye_pigmentation0.61986669
141MP0003935_abnormal_craniofacial_develop0.61380331

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)6.00877262
2Chromsome breakage (HP:0040012)5.68620525
3Abnormality of the preputium (HP:0100587)3.68155823
4Aplasia/Hypoplasia of the uvula (HP:0010293)3.65356343
5Abnormality of chromosome stability (HP:0003220)3.63318848
6Duplicated collecting system (HP:0000081)3.58283954
7Meckel diverticulum (HP:0002245)3.55192138
8Prostate neoplasm (HP:0100787)3.50216471
9Abnormality of the renal collecting system (HP:0004742)3.46803822
10Abnormality of the ileum (HP:0001549)3.43145031
11Birth length less than 3rd percentile (HP:0003561)3.26986853
12Colon cancer (HP:0003003)3.25051928
13Ectopic kidney (HP:0000086)3.22446346
14Reticulocytopenia (HP:0001896)3.11835170
15Abnormality of DNA repair (HP:0003254)2.96287457
16Clubbing of toes (HP:0100760)2.86323916
17Oligodactyly (hands) (HP:0001180)2.69138329
18Small intestinal stenosis (HP:0012848)2.56488640
19Duodenal stenosis (HP:0100867)2.56488640
20Duplication of thumb phalanx (HP:0009942)2.53332736
21Pancreatic fibrosis (HP:0100732)2.49152380
22Triphalangeal thumb (HP:0001199)2.48104227
23Nephroblastoma (Wilms tumor) (HP:0002667)2.47300143
2411 pairs of ribs (HP:0000878)2.45983444
25Myelodysplasia (HP:0002863)2.45078040
26Patellar aplasia (HP:0006443)2.43544848
27Bone marrow hypocellularity (HP:0005528)2.40250796
28Supernumerary spleens (HP:0009799)2.36763242
29Absent radius (HP:0003974)2.35657071
30Abnormality of the carotid arteries (HP:0005344)2.33989301
31Hypoplastic pelvis (HP:0008839)2.32752616
32Embryonal renal neoplasm (HP:0011794)2.31560953
33Medial flaring of the eyebrow (HP:0010747)2.30837516
34Oligodactyly (HP:0012165)2.28059390
35Sloping forehead (HP:0000340)2.24266979
36Abnormality of the columella (HP:0009929)2.23128255
37Rhabdomyosarcoma (HP:0002859)2.22352689
38Absent thumb (HP:0009777)2.22067263
39Aplasia involving forearm bones (HP:0009822)2.21570182
40Absent forearm bone (HP:0003953)2.21570182
41Lip pit (HP:0100267)2.20803393
42True hermaphroditism (HP:0010459)2.20226730
43Aplasia/Hypoplasia of the patella (HP:0006498)2.19597905
44Septo-optic dysplasia (HP:0100842)2.19231839
45Small hand (HP:0200055)2.15336446
46Optic nerve hypoplasia (HP:0000609)2.14833508
47Aplasia/Hypoplasia of the sternum (HP:0006714)2.11868940
48Breast hypoplasia (HP:0003187)2.10014568
49Abnormality of the prostate (HP:0008775)2.09345761
50Short thumb (HP:0009778)2.08832853
51Ependymoma (HP:0002888)2.08678400
52Preaxial hand polydactyly (HP:0001177)2.08324457
53Hyperglycinemia (HP:0002154)2.08024768
54Abnormality of the duodenum (HP:0002246)2.06764328
55Medulloblastoma (HP:0002885)2.04357738
56Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.03526296
57Pancreatic cysts (HP:0001737)2.03263824
58White forelock (HP:0002211)2.03012781
59Median cleft lip (HP:0000161)2.01954358
60Aplasia/Hypoplasia of the sacrum (HP:0008517)2.01197467
61Carpal bone hypoplasia (HP:0001498)2.00438444
62Abnormality of the fingertips (HP:0001211)1.98753903
63Abnormal lung lobation (HP:0002101)1.98008729
64Abnormality of the incisor (HP:0000676)1.97126101
65Acute necrotizing encephalopathy (HP:0006965)1.96407380
66Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.96046857
67Congenital primary aphakia (HP:0007707)1.95362800
68Abnormal number of incisors (HP:0011064)1.94996175
69Type I transferrin isoform profile (HP:0003642)1.94693377
70Tubulointerstitial nephritis (HP:0001970)1.94356882
71Patchy hypopigmentation of hair (HP:0011365)1.93924991
72Volvulus (HP:0002580)1.89668788
73Abnormality of incisor morphology (HP:0011063)1.89207991
74Abnormal biliary tract physiology (HP:0012439)1.88483511
75Bile duct proliferation (HP:0001408)1.88483511
76Abnormality of the labia minora (HP:0012880)1.86965326
77Methylmalonic acidemia (HP:0002912)1.86933631
78Cortical dysplasia (HP:0002539)1.86873406
79Acute encephalopathy (HP:0006846)1.86822340
80Facial hemangioma (HP:0000329)1.84995286
81Gonadotropin excess (HP:0000837)1.84253962
82Short tibia (HP:0005736)1.82921075
83Genital tract atresia (HP:0001827)1.81060227
84Impulsivity (HP:0100710)1.80895198
85Aplastic anemia (HP:0001915)1.80022773
86Aplasia/Hypoplasia of the tibia (HP:0005772)1.79997458
87Gait imbalance (HP:0002141)1.79736257
88Adrenal hypoplasia (HP:0000835)1.79650222
89Hypoplasia of the pons (HP:0012110)1.79547709
90Pendular nystagmus (HP:0012043)1.78038965
91Anencephaly (HP:0002323)1.77914583
92Nephrogenic diabetes insipidus (HP:0009806)1.77157908
93Glioma (HP:0009733)1.76219080
94Aplasia/Hypoplasia of the earlobes (HP:0009906)1.76182136
95Postaxial hand polydactyly (HP:0001162)1.75678867
96Vaginal atresia (HP:0000148)1.75290397
97Chronic hepatic failure (HP:0100626)1.74916476
98Dandy-Walker malformation (HP:0001305)1.74233496
99Postaxial foot polydactyly (HP:0001830)1.73936513
100Abnormality of the pons (HP:0007361)1.73923607
101Facial cleft (HP:0002006)1.73595083
102Abnormality of the septum pellucidum (HP:0007375)1.73438372
103Acute myeloid leukemia (HP:0004808)1.73126890
104Absent septum pellucidum (HP:0001331)1.72635828
105Acute lymphatic leukemia (HP:0006721)1.71494000
106Abnormality of cells of the erythroid lineage (HP:0012130)1.71224227
107Aplasia/Hypoplasia of the tongue (HP:0010295)1.70786584
108Premature graying of hair (HP:0002216)1.70744427
109Abnormal hair whorl (HP:0010721)1.70603258
110Nephronophthisis (HP:0000090)1.69930827
111Intestinal atresia (HP:0011100)1.68343862
112Anophthalmia (HP:0000528)1.68200087
113Increased CSF lactate (HP:0002490)1.67979173
114Sclerocornea (HP:0000647)1.67874435
115Abnormality of the anterior horn cell (HP:0006802)1.67831875
116Degeneration of anterior horn cells (HP:0002398)1.67831875
117Optic nerve coloboma (HP:0000588)1.67287134
118Abnormal mitochondria in muscle tissue (HP:0008316)1.67204862
119Renal cortical cysts (HP:0000803)1.67163493
120Holoprosencephaly (HP:0001360)1.67032293
121Tracheoesophageal fistula (HP:0002575)1.66660938
122Retrobulbar optic neuritis (HP:0100654)1.66478226
123Optic neuritis (HP:0100653)1.66478226
124Oligohydramnios (HP:0001562)1.64940380
125Abnormal spermatogenesis (HP:0008669)1.64659156
126Abnormality of midbrain morphology (HP:0002418)1.64642915
127Molar tooth sign on MRI (HP:0002419)1.64642915
128Selective tooth agenesis (HP:0001592)1.62725793
129Congenital sensorineural hearing impairment (HP:0008527)1.60504784
130Supernumerary bones of the axial skeleton (HP:0009144)1.60059320
131Leukopenia (HP:0001882)1.59225708
132Microvesicular hepatic steatosis (HP:0001414)1.58132283
133Poikiloderma (HP:0001029)1.57880712
134Horseshoe kidney (HP:0000085)1.57410944
135Aplasia cutis congenita (HP:0001057)1.57262314
136Astigmatism (HP:0000483)1.57245344
137Attenuation of retinal blood vessels (HP:0007843)1.57189592
138Ectropion (HP:0000656)1.56959619
139Aplasia/Hypoplasia of the fovea (HP:0008060)1.56837288
140Hypoplasia of the fovea (HP:0007750)1.56837288
141Abnormality of the parietal bone (HP:0002696)1.56766681
142Abnormality of the renal medulla (HP:0100957)1.56164840
143Abnormality of the nasal septum (HP:0000419)1.54544390
144Aganglionic megacolon (HP:0002251)1.53588742
145Cleft eyelid (HP:0000625)1.53003123
146Conical tooth (HP:0000698)1.52729702

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SRPK13.85075959
2ZAK2.88682797
3NEK12.86760042
4CDC72.78760944
5TRIM282.70966402
6MKNK22.63795306
7PLK42.54252870
8STK162.52678336
9TTK2.46967996
10MKNK12.37431208
11WEE12.22916970
12BRD42.20049675
13BUB12.17616214
14VRK12.02706212
15CLK11.98675632
16VRK21.98441918
17WNK31.97866254
18NEK21.90730913
19EIF2AK21.84256537
20MAP4K21.81917904
21IRAK31.80029682
22ATR1.78635652
23TXK1.74128892
24PNCK1.70319382
25NUAK11.63314243
26TLK11.61562848
27PLK11.60691227
28IRAK41.56583494
29BMPR1B1.49853454
30BRSK21.39720724
31DYRK31.38994501
32AKT31.36950279
33AURKB1.35178071
34YES11.34127397
35CDK121.33971962
36TAF11.33497002
37PLK31.32995288
38CHEK21.31909247
39PLK21.30279973
40STK41.28965017
41STK38L1.28196252
42CASK1.23504783
43CDK71.21311288
44SIK31.17646184
45MAP3K141.16570270
46FRK1.15898261
47NEK61.15693971
48TNIK1.14216356
49PASK1.12609468
50EPHA21.11005197
51STK31.10084218
52MELK1.08141033
53TEC1.04831704
54LATS11.00644958
55ATM0.99430411
56GRK10.98545336
57CDK30.96825657
58MAP3K40.95809389
59ACVR1B0.95718737
60CHEK10.94942696
61CDK80.92276481
62CCNB10.91792503
63NME20.88079281
64CSNK1G10.86476759
65MUSK0.86141229
66PBK0.85122927
67PDK20.84480645
68AURKA0.84163101
69RPS6KA50.84052458
70PIM10.83635874
71IKBKB0.75883705
72NME10.75408111
73STK390.75283522
74EIF2AK30.74782766
75BRAF0.73827840
76CDK40.72504173
77BMPR20.72067142
78CHUK0.71957219
79EIF2AK10.71900617
80MAPK130.71594822
81PRPF4B0.71042429
82ADRBK20.70908998
83NLK0.68558841
84MAP2K70.67703073
85KIT0.67668857
86CSNK1G30.66435163
87INSRR0.66097577
88BRSK10.65229399
89CDK90.64071026
90SGK20.63578419
91CDK190.63345737
92CSNK1G20.62990796
93BCR0.61861517
94FER0.59555386
95OXSR10.58540724
96DYRK20.58090792
97CSNK2A10.57716571
98TGFBR10.56631763
99CDK10.56568404
100CDK20.56435800
101CAMK1G0.55420838
102IKBKE0.54934569
103CSNK1E0.54554151
104TSSK60.54421182
105RPS6KB20.54294844
106ERBB30.53807847
107RPS6KA40.53052405
108CSNK1A1L0.53039960
109WNK40.50944361
110EPHA40.50080405
111MARK30.48008580
112PRKCI0.47622338
113NEK90.47621878
114BTK0.47541959
115CSNK2A20.45264373
116JAK30.42986758
117LYN0.42115956
118TRPM70.41435513
119PRKCG0.40295667
120RPS6KB10.39770567
121PRKCE0.37330260
122AKT10.37236523
123STK240.36210270
124MAP3K90.35605190
125MST40.34663580
126PKN10.34520259
127BLK0.34017659
128IRAK10.34012497
129MAPK140.33786813
130PRKDC0.33706557
131TNK20.33372655
132MAP3K80.32672578
133PRKACB0.31289849
134FLT30.26196707

Predicted pathways (KEGG)

RankGene SetZ-score
1Homologous recombination_Homo sapiens_hsa034403.80920612
2Fanconi anemia pathway_Homo sapiens_hsa034603.75450646
3DNA replication_Homo sapiens_hsa030303.67904412
4Mismatch repair_Homo sapiens_hsa034303.61309173
5RNA polymerase_Homo sapiens_hsa030202.88165568
6Non-homologous end-joining_Homo sapiens_hsa034502.86785893
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.68985025
8Nucleotide excision repair_Homo sapiens_hsa034202.63551825
9Base excision repair_Homo sapiens_hsa034102.56706429
10Basal transcription factors_Homo sapiens_hsa030222.46654975
11Cell cycle_Homo sapiens_hsa041102.42200970
12Spliceosome_Homo sapiens_hsa030402.40187861
13Ribosome_Homo sapiens_hsa030102.26221695
14RNA degradation_Homo sapiens_hsa030182.03758210
15Pyrimidine metabolism_Homo sapiens_hsa002402.02074602
16One carbon pool by folate_Homo sapiens_hsa006701.99867570
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.98194383
18RNA transport_Homo sapiens_hsa030131.97628365
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73771484
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.68207232
21Oxidative phosphorylation_Homo sapiens_hsa001901.61081987
22Proteasome_Homo sapiens_hsa030501.50627092
23Parkinsons disease_Homo sapiens_hsa050121.50572850
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.49170662
25p53 signaling pathway_Homo sapiens_hsa041151.49028280
26mRNA surveillance pathway_Homo sapiens_hsa030151.45346430
27Selenocompound metabolism_Homo sapiens_hsa004501.44474246
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43050331
29Propanoate metabolism_Homo sapiens_hsa006401.40345413
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.35982094
31Purine metabolism_Homo sapiens_hsa002301.33225645
32Herpes simplex infection_Homo sapiens_hsa051681.31195486
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.30769913
34Systemic lupus erythematosus_Homo sapiens_hsa053221.27473521
35Primary immunodeficiency_Homo sapiens_hsa053401.23249413
36Protein export_Homo sapiens_hsa030601.21616595
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.16164383
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.13854014
39Intestinal immune network for IgA production_Homo sapiens_hsa046721.07923131
40Hematopoietic cell lineage_Homo sapiens_hsa046401.04281145
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04249670
42Sphingolipid metabolism_Homo sapiens_hsa006001.02472577
43Phototransduction_Homo sapiens_hsa047441.01793963
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99643139
45Epstein-Barr virus infection_Homo sapiens_hsa051690.99539437
46Measles_Homo sapiens_hsa051620.95459562
47Autoimmune thyroid disease_Homo sapiens_hsa053200.94743914
48Pyruvate metabolism_Homo sapiens_hsa006200.94598619
49Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.93831756
50Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92544556
51Allograft rejection_Homo sapiens_hsa053300.91720774
52Arachidonic acid metabolism_Homo sapiens_hsa005900.89422397
53Fatty acid elongation_Homo sapiens_hsa000620.87890392
54Graft-versus-host disease_Homo sapiens_hsa053320.82759149
55Basal cell carcinoma_Homo sapiens_hsa052170.81852962
56Asthma_Homo sapiens_hsa053100.81174429
57NOD-like receptor signaling pathway_Homo sapiens_hsa046210.76587014
58Butanoate metabolism_Homo sapiens_hsa006500.76318601
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.76252462
60Glutathione metabolism_Homo sapiens_hsa004800.70760199
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70259293
62Viral carcinogenesis_Homo sapiens_hsa052030.70120706
63MicroRNAs in cancer_Homo sapiens_hsa052060.68561161
64Alzheimers disease_Homo sapiens_hsa050100.67705075
65Biosynthesis of amino acids_Homo sapiens_hsa012300.65474361
66Vitamin B6 metabolism_Homo sapiens_hsa007500.64565821
67SNARE interactions in vesicular transport_Homo sapiens_hsa041300.63219700
682-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.62419763
69Ether lipid metabolism_Homo sapiens_hsa005650.60552800
70Linoleic acid metabolism_Homo sapiens_hsa005910.60381381
71HTLV-I infection_Homo sapiens_hsa051660.60328029
72Metabolic pathways_Homo sapiens_hsa011000.58624815
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58432966
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.58130822
75Influenza A_Homo sapiens_hsa051640.58033821
76Antigen processing and presentation_Homo sapiens_hsa046120.56570078
77Olfactory transduction_Homo sapiens_hsa047400.56413865
78Small cell lung cancer_Homo sapiens_hsa052220.56236159
79Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53379267
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.51307258
81Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.50593677
82Notch signaling pathway_Homo sapiens_hsa043300.50342294
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.50183172
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50089772
85Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49943159
86Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.49900881
87Alcoholism_Homo sapiens_hsa050340.48123197
88TGF-beta signaling pathway_Homo sapiens_hsa043500.47864588
89Carbon metabolism_Homo sapiens_hsa012000.47799355
90alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.47474527
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47334383
92Apoptosis_Homo sapiens_hsa042100.47072905
93Hepatitis B_Homo sapiens_hsa051610.46601816
94Sulfur relay system_Homo sapiens_hsa041220.45221994
95Wnt signaling pathway_Homo sapiens_hsa043100.44477158
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44312642
97Cardiac muscle contraction_Homo sapiens_hsa042600.44181588
98Peroxisome_Homo sapiens_hsa041460.43473903
99Other glycan degradation_Homo sapiens_hsa005110.42072694
100Pathways in cancer_Homo sapiens_hsa052000.41140401
101Caffeine metabolism_Homo sapiens_hsa002320.40261284
102Hedgehog signaling pathway_Homo sapiens_hsa043400.39715611
103Nicotine addiction_Homo sapiens_hsa050330.39113222
104Fatty acid metabolism_Homo sapiens_hsa012120.37646124
105Prostate cancer_Homo sapiens_hsa052150.35820505
106Oocyte meiosis_Homo sapiens_hsa041140.35104941
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34084050
108Malaria_Homo sapiens_hsa051440.33216609
109Nitrogen metabolism_Homo sapiens_hsa009100.32567886
110Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32084633
111Hippo signaling pathway_Homo sapiens_hsa043900.31147110
112Regulation of autophagy_Homo sapiens_hsa041400.30925729
113TNF signaling pathway_Homo sapiens_hsa046680.30466884
114Tryptophan metabolism_Homo sapiens_hsa003800.30180884
115Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.29304621
116Leishmaniasis_Homo sapiens_hsa051400.29263170
117N-Glycan biosynthesis_Homo sapiens_hsa005100.29012076
118Hepatitis C_Homo sapiens_hsa051600.28858736
119Folate biosynthesis_Homo sapiens_hsa007900.28816537
120Toll-like receptor signaling pathway_Homo sapiens_hsa046200.28758704
121Maturity onset diabetes of the young_Homo sapiens_hsa049500.27672902
122Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.27542547
123Circadian rhythm_Homo sapiens_hsa047100.27049281
124Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.26483300
125Vitamin digestion and absorption_Homo sapiens_hsa049770.26066531
126Melanoma_Homo sapiens_hsa052180.25838628
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.25809929
128Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.25234016
129Lysine degradation_Homo sapiens_hsa003100.25074027
130Taste transduction_Homo sapiens_hsa047420.24915780
131Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24691165
132Legionellosis_Homo sapiens_hsa051340.23839797
133PI3K-Akt signaling pathway_Homo sapiens_hsa041510.23397778
134Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.23221880
135Steroid biosynthesis_Homo sapiens_hsa001000.20631254
136FoxO signaling pathway_Homo sapiens_hsa040680.19954304
137Huntingtons disease_Homo sapiens_hsa050160.19816800
138T cell receptor signaling pathway_Homo sapiens_hsa046600.18222934
139Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16674357
140Fatty acid degradation_Homo sapiens_hsa000710.14466538
141Arginine and proline metabolism_Homo sapiens_hsa003300.14263253
142beta-Alanine metabolism_Homo sapiens_hsa004100.13687271
143Retinol metabolism_Homo sapiens_hsa008300.10524379
144Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.07325216

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