CCDC80

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)7.37885570
2collagen fibril organization (GO:0030199)7.10854785
3low-density lipoprotein particle clearance (GO:0034383)5.52691603
4cartilage development involved in endochondral bone morphogenesis (GO:0060351)5.43867192
5kidney mesenchyme development (GO:0072074)5.21023271
6keratan sulfate catabolic process (GO:0042340)5.19360426
7metanephric mesenchyme development (GO:0072075)5.09455318
8extracellular fibril organization (GO:0043206)4.98189067
9regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.93310084
10cell migration involved in heart development (GO:0060973)4.87019026
11chondrocyte proliferation (GO:0035988)4.78796605
12collagen metabolic process (GO:0032963)4.77680350
13type B pancreatic cell proliferation (GO:0044342)4.76448306
14collagen catabolic process (GO:0030574)4.67120376
15multicellular organismal macromolecule metabolic process (GO:0044259)4.57891705
16fibril organization (GO:0097435)4.46180953
17bone trabecula formation (GO:0060346)4.44280013
18multicellular organismal metabolic process (GO:0044236)4.42833078
19dermatan sulfate biosynthetic process (GO:0030208)4.29654413
20multicellular organismal catabolic process (GO:0044243)4.29196380
21sequestering of extracellular ligand from receptor (GO:0035581)4.27815530
22retina vasculature morphogenesis in camera-type eye (GO:0061299)4.19934662
23endodermal cell differentiation (GO:0035987)4.18217483
24blood vessel maturation (GO:0001955)4.01909725
25positive regulation of fatty acid oxidation (GO:0046321)4.01013636
26regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.97035069
27chondrocyte development (GO:0002063)3.93447282
28dermatan sulfate metabolic process (GO:0030205)3.93016190
29extracellular matrix disassembly (GO:0022617)3.90208701
30skin morphogenesis (GO:0043589)3.89231689
31cellular response to vitamin (GO:0071295)3.85433945
32adhesion of symbiont to host cell (GO:0044650)3.79551876
33virion attachment to host cell (GO:0019062)3.79551876
34positive regulation of fatty acid beta-oxidation (GO:0032000)3.78175709
35apoptotic cell clearance (GO:0043277)3.69607900
36extracellular regulation of signal transduction (GO:1900115)3.62871428
37extracellular negative regulation of signal transduction (GO:1900116)3.62871428
38positive regulation of endothelial cell apoptotic process (GO:2000353)3.56357665
39extracellular matrix assembly (GO:0085029)3.55955404
40smooth muscle tissue development (GO:0048745)3.55085640
41negative regulation of fatty acid transport (GO:2000192)3.53532348
42positive regulation of extracellular matrix organization (GO:1903055)3.53185409
43endothelial cell morphogenesis (GO:0001886)3.48411441
44white fat cell differentiation (GO:0050872)3.46632387
45peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.45000839
46cell adhesion mediated by integrin (GO:0033627)3.41719101
47regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.38179927
48regulation of sequestering of triglyceride (GO:0010889)3.35461505
49wound healing, spreading of epidermal cells (GO:0035313)3.34853588
50regulation of integrin-mediated signaling pathway (GO:2001044)3.33805236
51venous blood vessel morphogenesis (GO:0048845)3.33647522
52basement membrane organization (GO:0071711)3.31479829
53pericardium development (GO:0060039)3.30410750
54negative regulation of cartilage development (GO:0061037)3.28886642
55barbed-end actin filament capping (GO:0051016)3.28816605
56positive regulation of osteoblast proliferation (GO:0033690)3.26115785
57regulation of extracellular matrix disassembly (GO:0010715)3.24583520
58chondroitin sulfate biosynthetic process (GO:0030206)3.23611784
59* extracellular matrix organization (GO:0030198)3.22977267
60substrate adhesion-dependent cell spreading (GO:0034446)3.22211740
61neuron projection extension involved in neuron projection guidance (GO:1902284)3.21869587
62axon extension involved in axon guidance (GO:0048846)3.21869587
63* extracellular structure organization (GO:0043062)3.21515620
64brown fat cell differentiation (GO:0050873)3.20693393
65positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr3.18640487
66iron ion import (GO:0097286)3.18225221
67cell proliferation involved in metanephros development (GO:0072203)3.17923813
68negative regulation of BMP signaling pathway (GO:0030514)3.17911491
69positive regulation of fibroblast migration (GO:0010763)3.17120389
70cell migration involved in sprouting angiogenesis (GO:0002042)3.13905401
71glomerular basement membrane development (GO:0032836)3.12230034
72adhesion of symbiont to host (GO:0044406)3.11032454
73peptidyl-proline hydroxylation (GO:0019511)3.09144579
74glomerular filtration (GO:0003094)3.09051596
75regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.08219897
76phagocytosis, recognition (GO:0006910)3.06610945
77tooth mineralization (GO:0034505)3.04879761
78negative regulation of chondrocyte differentiation (GO:0032331)3.03606917
79triglyceride catabolic process (GO:0019433)3.03414057
80cell aggregation (GO:0098743)2.99807831
81cartilage condensation (GO:0001502)2.99807831
82positive regulation of glycogen biosynthetic process (GO:0045725)2.96930046
83negative regulation of smooth muscle cell migration (GO:0014912)2.96466312
84regulation of macrophage cytokine production (GO:0010935)2.94377079
85insulin-like growth factor receptor signaling pathway (GO:0048009)2.93542987
86positive regulation of cartilage development (GO:0061036)2.92064208
87lipid particle organization (GO:0034389)2.91803174
88cell-substrate junction assembly (GO:0007044)2.91699663
89regulation of plasminogen activation (GO:0010755)2.91305836
90protein hydroxylation (GO:0018126)2.89721181
91negative regulation of osteoblast proliferation (GO:0033689)2.88137653
92endocardial cushion development (GO:0003197)2.87962401
93growth hormone receptor signaling pathway (GO:0060396)2.87780205
94heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.87302222
95positive regulation of fatty acid metabolic process (GO:0045923)2.87073843
96renal filtration (GO:0097205)2.85401954
97chondroitin sulfate catabolic process (GO:0030207)2.83591950
98regulation of cartilage development (GO:0061035)2.83246221
99positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.82174885
100membrane raft organization (GO:0031579)2.81673591
101ovulation from ovarian follicle (GO:0001542)2.80291680
102cellular response to vitamin D (GO:0071305)2.79544491
103vascular endothelial growth factor signaling pathway (GO:0038084)2.79532922
104positive regulation of fat cell differentiation (GO:0045600)2.78891521
105cellular response to amino acid stimulus (GO:0071230)2.78676362
106protein retention in ER lumen (GO:0006621)2.78620804
107middle ear morphogenesis (GO:0042474)2.77865912
108mesenchymal cell differentiation involved in kidney development (GO:0072161)2.77704245
109mesenchymal cell differentiation involved in renal system development (GO:2001012)2.77704245
110negative regulation of leukocyte chemotaxis (GO:0002689)2.76054238
111substrate-dependent cell migration (GO:0006929)2.76013516
112mesenchymal-epithelial cell signaling (GO:0060638)2.75824562
113positive regulation of blood vessel endothelial cell migration (GO:0043536)2.75269077
114regulation of cholesterol storage (GO:0010885)2.74643904
115regulation of fatty acid beta-oxidation (GO:0031998)2.74581258
116plasma membrane repair (GO:0001778)2.73950953
117lymphangiogenesis (GO:0001946)2.73886151
118embryonic cranial skeleton morphogenesis (GO:0048701)2.71933200
119positive regulation of macrophage cytokine production (GO:0060907)2.70483737
120muscle cell migration (GO:0014812)2.69031960
121maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.69015511
122replacement ossification (GO:0036075)2.68601426
123endochondral ossification (GO:0001958)2.68601426
124epithelial cell-cell adhesion (GO:0090136)2.68109658
125regulation of osteoblast proliferation (GO:0033688)2.68098627
126cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.65467590
127craniofacial suture morphogenesis (GO:0097094)2.64477444
128neutral lipid catabolic process (GO:0046461)2.63573595
129acylglycerol catabolic process (GO:0046464)2.63573595
130regulation of fatty acid oxidation (GO:0046320)2.63433717
131negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.63305159
132protein localization to cell surface (GO:0034394)2.63139595
133regulation of chemokine-mediated signaling pathway (GO:0070099)2.62364039
134hemidesmosome assembly (GO:0031581)2.61979497
135regulation of chondrocyte differentiation (GO:0032330)2.61781900
136stress fiber assembly (GO:0043149)2.61717018
137positive regulation of glucose import (GO:0046326)2.61162546
138regulation of smooth muscle cell migration (GO:0014910)2.60788699
139face morphogenesis (GO:0060325)2.60271284
140negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.59940860
141valine metabolic process (GO:0006573)2.59877085
142wound healing, spreading of cells (GO:0044319)2.59029606
143planar cell polarity pathway involved in neural tube closure (GO:0090179)2.58978185
144regulation of tight junction assembly (GO:2000810)2.58831588
145regulation of phospholipase A2 activity (GO:0032429)2.58794457

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human7.28389463
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.73685024
3TP63_17297297_ChIP-ChIP_HaCaT_Human4.83767913
4RARG_19884340_ChIP-ChIP_MEFs_Mouse4.60478391
5CLOCK_20551151_ChIP-Seq_293T_Human3.89325834
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.62730623
7* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.17886937
8* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.77284086
9CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.67787477
10* CJUN_26792858_Chip-Seq_BT549_Human2.66115750
11* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.64405344
12* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.53210906
13* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.43621395
14SMAD_19615063_ChIP-ChIP_OVARY_Human2.25064765
15ESR1_21235772_ChIP-Seq_MCF-7_Human2.18221619
16EP300_21415370_ChIP-Seq_HL-1_Mouse2.07978178
17NRF2_20460467_ChIP-Seq_MEFs_Mouse2.07904810
18NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.07904810
19WT1_19549856_ChIP-ChIP_CCG9911_Human2.07612003
20HIF1A_21447827_ChIP-Seq_MCF-7_Human2.03046252
21NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.94448355
22PPAR_26484153_Chip-Seq_NCI-H1993_Human1.93490365
23CDX2_19796622_ChIP-Seq_MESCs_Mouse1.81208740
24SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.80585802
25* BRD4_25478319_ChIP-Seq_HGPS_Human1.74282554
26ESR2_21235772_ChIP-Seq_MCF-7_Human1.69302816
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.54180507
28WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.53718511
29EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.51381609
30GATA2_21666600_ChIP-Seq_HMVEC_Human1.51154464
31JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.50183094
32PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.46871286
33* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.46438918
34TP53_18474530_ChIP-ChIP_U2OS_Human1.44310186
35SOX2_20726797_ChIP-Seq_SW620_Human1.43170336
36* TBX20_22328084_ChIP-Seq_HEART_Mouse1.42100906
37* TBX20_22080862_ChIP-Seq_HEART_Mouse1.42100906
38* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.42022467
39FOXO3_23340844_ChIP-Seq_DLD1_Human1.41828287
40SALL4_18804426_ChIP-ChIP_XEN_Mouse1.36369462
41BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.36229268
42ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.35810781
43SMC1_22415368_ChIP-Seq_MEFs_Mouse1.35632204
44* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.35553478
45STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.35184164
46EED_16625203_ChIP-ChIP_MESCs_Mouse1.35120361
47SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.33492265
48SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.33492265
49MTF2_20144788_ChIP-Seq_MESCs_Mouse1.33256724
50* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.30919748
51FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.29715314
52NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.29511114
53SOX9_24532713_ChIP-Seq_HFSC_Mouse1.29364614
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.29351106
55EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29247866
56RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29247866
57GBX2_23144817_ChIP-Seq_PC3_Human1.27908221
58SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.23244506
59TP53_20018659_ChIP-ChIP_R1E_Mouse1.22013543
60LXR_22158963_ChIP-Seq_LIVER_Mouse1.20925228
61JARID2_20075857_ChIP-Seq_MESCs_Mouse1.18675785
62* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18392152
63NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.16498519
64* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.14504567
65TP53_22127205_ChIP-Seq_IMR90_Human1.14487678
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.13131087
67AR_21572438_ChIP-Seq_LNCaP_Human1.12923368
68RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.12802498
69AHR_22903824_ChIP-Seq_MCF-7_Human1.12444307
70TP53_16413492_ChIP-PET_HCT116_Human1.12329617
71SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11559463
72SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.10889639
73SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.09868957
74P63_26484246_Chip-Seq_KERATINOCYTES_Human1.08633932
75RXR_22158963_ChIP-Seq_LIVER_Mouse1.07812779
76WT1_25993318_ChIP-Seq_PODOCYTE_Human1.07256375
77THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.06851551
78TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06683194
79SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.06388740
80SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.05423244
81CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04854782
82RNF2_27304074_Chip-Seq_ESCs_Mouse1.04599954
83GATA1_22025678_ChIP-Seq_K562_Human1.04322549
84RBPJ_22232070_ChIP-Seq_NCS_Mouse1.02605201
85VDR_24787735_ChIP-Seq_THP-1_Human1.02434543
86PIAS1_25552417_ChIP-Seq_VCAP_Human1.00901391
87* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.00353364
88* SMC3_22415368_ChIP-Seq_MEFs_Mouse0.99363504
89NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.98961279
90RXR_22108803_ChIP-Seq_LS180_Human0.97901850
91SA1_22415368_ChIP-Seq_MEFs_Mouse0.97533409
92ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96655692
93ARNT_22903824_ChIP-Seq_MCF-7_Human0.96369975
94UBF1/2_26484160_Chip-Seq_HMECs_Human0.95977698
95KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94465936
96ESR1_20079471_ChIP-ChIP_T-47D_Human0.93683019
97HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.93223618
98ZFP57_27257070_Chip-Seq_ESCs_Mouse0.92768735
99PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.91093986
100MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.91038025
101EZH2_27304074_Chip-Seq_ESCs_Mouse0.90524483
102SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.90514202
103ATF3_27146783_Chip-Seq_COLON_Human0.90433744
104TP53_23651856_ChIP-Seq_MEFs_Mouse0.89959961
105RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.89729033
106JARID2_20064375_ChIP-Seq_MESCs_Mouse0.89387871
107TBX3_20139965_ChIP-Seq_ESCs_Mouse0.88065350
108TBX3_20139965_ChIP-Seq_MESCs_Mouse0.87972748
109PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.87448324
110PPARD_21283829_ChIP-Seq_MYOFIBROBLAST_Human0.86348323
111TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.85885315
112TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.85256739
113SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.84429852
114* TP63_23658742_ChIP-Seq_EP156T_Human0.82314197
115TCF4_18268006_ChIP-ChIP_LS174T_Human0.81665369
116ISL1_27105846_Chip-Seq_CPCs_Mouse0.81149292
117UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.79522152
118SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.79498484
119* CSB_26484114_Chip-Seq_FIBROBLAST_Human0.79446671
120GATA3_24758297_ChIP-Seq_MCF-7_Human0.78810290
121FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.77549098
122NFIB_24661679_ChIP-Seq_LUNG_Mouse0.76169920

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen8.93444029
2MP0005275_abnormal_skin_tensile5.87405539
3MP0005503_abnormal_tendon_morphology5.62673999
4MP0003705_abnormal_hypodermis_morpholog3.85029796
5MP0003279_aneurysm3.34588726
6MP0001958_emphysema3.07307569
7MP0005670_abnormal_white_adipose2.86905045
8MP0004272_abnormal_basement_membrane2.65025369
9MP0009384_cardiac_valve_regurgitation2.47782577
10MP0003566_abnormal_cell_adhesion2.14568513
11MP0000013_abnormal_adipose_tissue2.12182270
12MP0002060_abnormal_skin_morphology2.10633192
13MP0005666_abnormal_adipose_tissue2.06683518
14MP0005508_abnormal_skeleton_morphology2.01526780
15MP0002108_abnormal_muscle_morphology1.97951464
16MP0001542_abnormal_bone_strength1.90164930
17MP0002933_joint_inflammation1.87450538
18MP0002295_abnormal_pulmonary_circulatio1.81834850
19MP0004185_abnormal_adipocyte_glucose1.81556341
20MP0004134_abnormal_chest_morphology1.81427795
21MP0005375_adipose_tissue_phenotype1.77215747
22MP0009250_abnormal_appendicular_skeleto1.74261076
23MP0004130_abnormal_muscle_cell1.74071429
24MP0000751_myopathy1.70914892
25MP0002837_dystrophic_cardiac_calcinosis1.67049399
26MP0005623_abnormal_meninges_morphology1.60803181
27MP0000003_abnormal_adipose_tissue1.54114355
28MP0000163_abnormal_cartilage_morphology1.49405764
29MP0005023_abnormal_wound_healing1.48070690
30MP0006054_spinal_hemorrhage1.44596225
31MP0005171_absent_coat_pigmentation1.43923477
32MP0005390_skeleton_phenotype1.43292814
33MP0003941_abnormal_skin_development1.42610828
34MP0010368_abnormal_lymphatic_system1.41691048
35MP0001243_abnormal_dermal_layer1.36674538
36MP0002115_abnormal_skeleton_extremities1.34068352
37MP0009780_abnormal_chondrocyte_physiolo1.31768293
38MP0002896_abnormal_bone_mineralization1.30043608
39MP0002282_abnormal_trachea_morphology1.27798888
40MP0003283_abnormal_digestive_organ1.27354789
41MP0005257_abnormal_intraocular_pressure1.26603235
42MP0010386_abnormal_urinary_bladder1.26516306
43MP0001533_abnormal_skeleton_physiology1.26000569
44MP0000534_abnormal_ureter_morphology1.24087589
45MP0003091_abnormal_cell_migration1.16147254
46MP0002998_abnormal_bone_remodeling1.14361614
47MP0000343_altered_response_to1.11922809
48MP0002113_abnormal_skeleton_development1.11018019
49MP0009115_abnormal_fat_cell1.06677848
50MP0004858_abnormal_nervous_system1.06319026
51MP0003045_fibrosis1.06216773
52MP0003646_muscle_fatigue1.05540438
53MP0001299_abnormal_eye_distance/1.03721349
54MP0010352_gastrointestinal_tract_polyps1.02580156
55MP0001879_abnormal_lymphatic_vessel1.02095234
56MP0003385_abnormal_body_wall1.00198730
57MP0000750_abnormal_muscle_regeneration0.99657194
58MP0003724_increased_susceptibility_to0.99317940
59MP0005164_abnormal_response_to0.99070461
60MP0001348_abnormal_lacrimal_gland0.98417158
61MP0002168_other_aberrant_phenotype0.96981614
62MP0000767_abnormal_smooth_muscle0.95768708
63MP0003828_pulmonary_edema0.94087836
64MP0000733_abnormal_muscle_development0.91237522
65MP0002971_abnormal_brown_adipose0.91080207
66MP0003950_abnormal_plasma_membrane0.90496153
67MP0003795_abnormal_bone_structure0.88641039
68MP0000749_muscle_degeneration0.87734025
69MP0006138_congestive_heart_failure0.87235896
70MP0003448_altered_tumor_morphology0.84714288
71MP0005595_abnormal_vascular_smooth0.83193390
72MP0008775_abnormal_heart_ventricle0.83086206
73MP0003959_abnormal_lean_body0.82913164
74MP0010030_abnormal_orbit_morphology0.82309370
75MP0009053_abnormal_anal_canal0.81668286
76MP0002089_abnormal_postnatal_growth/wei0.79832655
77MP0002133_abnormal_respiratory_system0.79728116
78MP0005388_respiratory_system_phenotype0.79728116
79MP0000759_abnormal_skeletal_muscle0.79080806
80MP0004087_abnormal_muscle_fiber0.78431285
81MP0000049_abnormal_middle_ear0.76294774
82MP0004084_abnormal_cardiac_muscle0.73882380
83MP0002128_abnormal_blood_circulation0.71671096
84MP0005620_abnormal_muscle_contractility0.71167445
85MP0000762_abnormal_tongue_morphology0.70707232
86MP0005330_cardiomyopathy0.70639147
87MP0005334_abnormal_fat_pad0.70250562
88MP0002932_abnormal_joint_morphology0.70210153
89MP0002876_abnormal_thyroid_physiology0.68768654
90MP0001544_abnormal_cardiovascular_syste0.68490313
91MP0005385_cardiovascular_system_phenoty0.68490313
92MP0002109_abnormal_limb_morphology0.68176715
93MP0000462_abnormal_digestive_system0.66306964
94MP0005369_muscle_phenotype0.65958621
95MP0001849_ear_inflammation0.63895038
96MP0001177_atelectasis0.63657274
97MP0004883_abnormal_blood_vessel0.63248025
98MP0002970_abnormal_white_adipose0.63234002
99MP0005165_increased_susceptibility_to0.63001104
100MP0002972_abnormal_cardiac_muscle0.62936425
101MP0002877_abnormal_melanocyte_morpholog0.62583188
102MP0004036_abnormal_muscle_relaxation0.61965348
103MP0001661_extended_life_span0.61787497
104MP0005076_abnormal_cell_differentiation0.60799334
105MP0001175_abnormal_lung_morphology0.60531885
106MP0003755_abnormal_palate_morphology0.60163859
107MP0001614_abnormal_blood_vessel0.59508085
108MP0003300_gastrointestinal_ulcer0.58958572
109MP0003942_abnormal_urinary_system0.58584336
110MP0002114_abnormal_axial_skeleton0.58024374
111MP0005197_abnormal_uvea_morphology0.57698416
112MP0002116_abnormal_craniofacial_bone0.57664256
113MP0002111_abnormal_tail_morphology0.56959981
114MP0002249_abnormal_larynx_morphology0.55762702
115MP0003115_abnormal_respiratory_system0.55466310
116MP0000538_abnormal_urinary_bladder0.53983132
117MP0000432_abnormal_head_morphology0.53091280
118MP0000428_abnormal_craniofacial_morphol0.52954600
119MP0000858_altered_metastatic_potential0.52572670
120MP0005193_abnormal_anterior_eye0.51280250
121MP0003935_abnormal_craniofacial_develop0.50892116
122MP0000467_abnormal_esophagus_morphology0.50247427
123MP0002925_abnormal_cardiovascular_devel0.49657316
124MP0004233_abnormal_muscle_weight0.46608870

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)7.41858319
2Premature rupture of membranes (HP:0001788)7.18919967
3Aortic dissection (HP:0002647)4.44237159
4Soft skin (HP:0000977)4.20231293
5Aortic aneurysm (HP:0004942)4.09740966
6Neonatal short-limb short stature (HP:0008921)3.98168651
7Broad metatarsal (HP:0001783)3.96285048
8Ankle contracture (HP:0006466)3.94401005
9Epiphyseal dysplasia (HP:0002656)3.80198520
10Cervical subluxation (HP:0003308)3.69635915
11Shallow orbits (HP:0000586)3.53295044
12Dilatation of the ascending aorta (HP:0005111)3.49620536
13Cerebral aneurysm (HP:0004944)3.49361964
14Peritonitis (HP:0002586)3.49096077
15Atrophic scars (HP:0001075)3.45284595
16Bladder diverticulum (HP:0000015)3.41813639
17Aortic regurgitation (HP:0001659)3.39533359
18Biconcave vertebral bodies (HP:0004586)3.37758029
19Genu recurvatum (HP:0002816)3.35535712
20Follicular hyperkeratosis (HP:0007502)3.32613432
21Mild short stature (HP:0003502)3.27157056
22Osteoarthritis (HP:0002758)3.25688242
23Vertebral compression fractures (HP:0002953)3.23979598
24Fragile skin (HP:0001030)3.20549195
25Wormian bones (HP:0002645)3.20477045
26Increased connective tissue (HP:0009025)3.19361615
27Spinal rigidity (HP:0003306)3.18147071
28Mitral valve prolapse (HP:0001634)3.16182420
29Blue sclerae (HP:0000592)3.12015338
30Abnormality of dentin (HP:0010299)3.11837022
31Metaphyseal cupping (HP:0003021)3.10233117
32Cupped ribs (HP:0000887)3.04789593
33Type 1 muscle fiber predominance (HP:0003803)3.03985537
34Beaking of vertebral bodies (HP:0004568)3.00286574
35Coxa vara (HP:0002812)2.97466012
36Irregular epiphyses (HP:0010582)2.93240363
37Aortic valve stenosis (HP:0001650)2.87178137
38Abnormality of the acetabulum (HP:0003170)2.86869909
39Hypoplastic ischia (HP:0003175)2.86387344
40Vascular tortuosity (HP:0004948)2.79544497
41Small epiphyses (HP:0010585)2.74989900
42Platyspondyly (HP:0000926)2.74078866
43Ectopia lentis (HP:0001083)2.67667995
44Overgrowth (HP:0001548)2.66044780
45Broad ribs (HP:0000885)2.54905165
46Abnormality of the ischium (HP:0003174)2.54326892
47Hyperextensible skin (HP:0000974)2.52193871
48Irregular vertebral endplates (HP:0003301)2.50024158
49Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.49282901
50Coronal craniosynostosis (HP:0004440)2.46670610
51Mitral stenosis (HP:0001718)2.45746752
52Limited hip movement (HP:0008800)2.45068416
53Joint stiffness (HP:0001387)2.43381184
54Abnormality of the vertebral endplates (HP:0005106)2.41343178
55Increased variability in muscle fiber diameter (HP:0003557)2.38699960
56Vitreoretinal degeneration (HP:0000655)2.38410232
57Abnormal tarsal ossification (HP:0008369)2.38124643
58Hip contracture (HP:0003273)2.36612326
59Joint laxity (HP:0001388)2.36567914
60Abnormal delivery (HP:0001787)2.36412800
61Metaphyseal dysplasia (HP:0100255)2.32949572
62Acanthosis nigricans (HP:0000956)2.32763021
63Delayed epiphyseal ossification (HP:0002663)2.31117569
64Ovoid vertebral bodies (HP:0003300)2.30096450
65Striae distensae (HP:0001065)2.29534229
66Flat acetabular roof (HP:0003180)2.29117361
67Hypoventilation (HP:0002791)2.27598811
68Pulmonary artery stenosis (HP:0004415)2.27583731
69Wrist flexion contracture (HP:0001239)2.24714828
70Genu varum (HP:0002970)2.22057855
71Slender build (HP:0001533)2.21898371
72Thin bony cortex (HP:0002753)2.21670095
73Hypoplasia of the iris (HP:0007676)2.21204724
74Aneurysm (HP:0002617)2.19011629
75Spinal cord compression (HP:0002176)2.16965562
76Muscle fiber splitting (HP:0003555)2.16905982
77Mildly elevated creatine phosphokinase (HP:0008180)2.14584935
78Redundant skin (HP:0001582)2.14422650
79Bowel diverticulosis (HP:0005222)2.12348388
80Absent frontal sinuses (HP:0002688)2.11896748
81Lumbar hyperlordosis (HP:0002938)2.11392209
82Delayed closure of the anterior fontanelle (HP:0001476)2.11368549
83Infantile muscular hypotonia (HP:0008947)2.11287169
84Mesomelia (HP:0003027)2.11194300
85Broad long bones (HP:0005622)2.11130572
86Arterial tortuosity (HP:0005116)2.10457448
87Flat capital femoral epiphysis (HP:0003370)2.08297976
88Abnormality of skeletal muscle fiber size (HP:0012084)2.08018806
89Tibial bowing (HP:0002982)2.07647840
90Spondylolisthesis (HP:0003302)2.07475186
91Camptodactyly of toe (HP:0001836)2.06875796
92Elbow flexion contracture (HP:0002987)2.04927981
93Osteolytic defects of the phalanges of the hand (HP:0009771)2.04210431
94Osteolytic defects of the hand bones (HP:0009699)2.04210431
95Flat cornea (HP:0007720)2.03453779
96Mitral regurgitation (HP:0001653)2.03285520
97Hydroxyprolinuria (HP:0003080)2.02331407
98Abnormality of proline metabolism (HP:0010907)2.02331407
99Wide anterior fontanel (HP:0000260)2.02317109
100Inguinal hernia (HP:0000023)2.01368585
101Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.01318677
102Abnormality of femoral epiphyses (HP:0006499)2.01318677
103Breech presentation (HP:0001623)2.01298207
104Hypoplasia of the odontoid process (HP:0003311)1.99210323
105Disproportionate tall stature (HP:0001519)1.98467300
106Flared iliac wings (HP:0002869)1.97384525
107Abnormal foot bone ossification (HP:0010675)1.97012168
108Cardiovascular calcification (HP:0011915)1.94608359
109Delayed cranial suture closure (HP:0000270)1.94512598
110Abnormal vertebral ossification (HP:0100569)1.90895016
111Bell-shaped thorax (HP:0001591)1.90601666
112Generalized amyotrophy (HP:0003700)1.88960686
113Oligomenorrhea (HP:0000876)1.87763499
114Right ventricular cardiomyopathy (HP:0011663)1.87659358
115Abnormality of carpal bone ossification (HP:0006257)1.86969484
116Protruding ear (HP:0000411)1.86779285
117Nonimmune hydrops fetalis (HP:0001790)1.86634557
118Short nail (HP:0001799)1.86205819
119Round ear (HP:0100830)1.86013283
120Venous abnormality (HP:0002624)1.84620834
121Abnormality of the lumbar spine (HP:0100712)1.83910056
122Venous insufficiency (HP:0005293)1.83205088
123Deviation of the hallux (HP:0010051)1.82524147
124Abnormality of skull ossification (HP:0002703)1.81990546
125Spinal cord lesions (HP:0100561)1.81559015
126Syringomyelia (HP:0003396)1.81559015
127Hallux valgus (HP:0001822)1.81319196
128Abnormality of the odontoid process (HP:0003310)1.80954172
129Knee flexion contracture (HP:0006380)1.80921906
130Abnormality of the epiphysis of the femoral head (HP:0010574)1.80778125
131Emphysema (HP:0002097)1.79625385
132Ulnar bowing (HP:0003031)1.78712076
133Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.77465061
134Abnormality of the anterior chamber (HP:0000593)1.73731881
135Persistence of primary teeth (HP:0006335)1.72582253
136Natal tooth (HP:0000695)1.72316100
137Thoracolumbar scoliosis (HP:0002944)1.71057385
138Femoral bowing (HP:0002980)1.70626420

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.88838900
2DDR24.86520556
3SIK13.22636130
4STK38L3.09766025
5TTN3.04386127
6CAMK1D2.84720389
7PDGFRA2.77082421
8ERN12.53704299
9LATS12.34942845
10LATS22.32729855
11RIPK12.07024598
12STK242.04998757
13PIK3CA1.97757682
14EPHA31.97164861
15EPHB21.97136577
16TRPM71.86138214
17CAMK1G1.81905623
18FER1.75279003
19PIM21.74082314
20PKN21.66239370
21STK381.66207592
22LMTK21.64908812
23TGFBR21.57251096
24STK31.54830501
25FRK1.54336966
26NEK91.53109550
27MYLK1.49800637
28MST1R1.48964532
29ERBB31.42659308
30PAK21.39651846
31MAP3K61.38609864
32FGFR31.31962492
33PAK31.27937883
34MET1.26817191
35MAP3K31.24450691
36PDK21.22703469
37BCKDK1.21003581
38MAPK71.14370880
39WNK11.13125273
40PRKG21.11194635
41PTK2B1.10925431
42DMPK1.09643200
43JAK11.06854001
44PDK41.05929408
45PDK31.05929408
46PDGFRB1.05373329
47BMX1.04956754
48AKT31.03035108
49MUSK1.02895987
50ILK0.98815618
51ROCK10.97615749
52MAP2K10.96378218
53FGFR10.93982155
54GRK50.89769599
55PTK20.89388052
56RPS6KA20.88326182
57ERBB40.88069238
58PIK3CG0.85055607
59MAPKAPK30.81655642
60PRKCH0.81210418
61CDK60.79905041
62PLK20.79377815
63TESK10.78555576
64NUAK10.77128070
65PAK60.74024724
66ABL20.73824141
67PRKAA20.72078861
68MAP3K70.70790918
69MTOR0.70387671
70GRK70.66203998
71LRRK20.64300742
72PRKD10.63345711
73INSR0.63263033
74TIE10.62561950
75ZAK0.60747272
76FGFR40.58999588
77PTK60.56920328
78EPHB10.56273580
79FGFR20.55424596
80PRKD30.55000248
81IGF1R0.54635898
82CAMKK20.53853223
83CLK10.53762717
84EEF2K0.53189636
85PRKD20.53053276
86PAK40.50073283
87RET0.49480989
88CAMK2G0.49337286
89DAPK30.49028989
90TGFBR10.48288895
91GRK10.47602591
92CDK90.47322647
93LIMK10.45789559
94KIT0.45320346
95JAK30.44813858
96MARK20.44677901
97FLT30.44084509
98PHKG10.43614048
99PHKG20.43614048
100CDK80.42809111
101NME20.42244133
102MOS0.41187653
103NTRK10.40177738
104SRC0.38829912
105MAP3K120.38775485
106TYK20.38266610
107MAP2K30.36449711
108RPS6KA40.35659548
109GSK3A0.35495338
110ROCK20.34278851
111MARK10.34057717
112ABL10.33791884
113MAPK40.33622216
114CAMK10.32964246
115ADRBK10.31917884
116ADRBK20.31597358
117PRKCE0.31381406
118ICK0.31036640
119PAK10.30450621
120CDC42BPA0.29569452
121EIF2AK20.28920458
122CAMK2D0.28490629
123RPS6KL10.26943492
124RPS6KC10.26943492
125JAK20.26443681
126OBSCN0.26422979
127MAPKAPK20.24988818
128MELK0.22761254
129MAPK10.21178768
130NLK0.20889242
131PRKACG0.19263052
132TAOK10.18075092

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045124.92959520
2Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005323.61270214
3Regulation of lipolysis in adipocytes_Homo sapiens_hsa049233.23729483
4Protein digestion and absorption_Homo sapiens_hsa049743.22570626
5Focal adhesion_Homo sapiens_hsa045102.98964954
6PPAR signaling pathway_Homo sapiens_hsa033202.60292322
7Malaria_Homo sapiens_hsa051442.59743225
8Fatty acid biosynthesis_Homo sapiens_hsa000612.22690875
9AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.97275745
10Proteoglycans in cancer_Homo sapiens_hsa052051.89106607
11Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.88585699
12Amoebiasis_Homo sapiens_hsa051461.87831039
13TGF-beta signaling pathway_Homo sapiens_hsa043501.87654362
14Dilated cardiomyopathy_Homo sapiens_hsa054141.79764479
15Propanoate metabolism_Homo sapiens_hsa006401.62500536
16Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.60083670
17PI3K-Akt signaling pathway_Homo sapiens_hsa041511.58302065
18Adipocytokine signaling pathway_Homo sapiens_hsa049201.55241014
19Fatty acid metabolism_Homo sapiens_hsa012121.47226777
20Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.40484909
21AMPK signaling pathway_Homo sapiens_hsa041521.38004495
22Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.33849215
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.32915976
24Adherens junction_Homo sapiens_hsa045201.30071284
25Small cell lung cancer_Homo sapiens_hsa052221.28886172
26Bladder cancer_Homo sapiens_hsa052191.19490328
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19315473
28Fatty acid degradation_Homo sapiens_hsa000711.12378769
29Insulin resistance_Homo sapiens_hsa049311.11497045
30Hippo signaling pathway_Homo sapiens_hsa043901.11101960
31Glycerolipid metabolism_Homo sapiens_hsa005611.09032237
32Axon guidance_Homo sapiens_hsa043601.08843382
33Viral myocarditis_Homo sapiens_hsa054161.08765056
34Phospholipase D signaling pathway_Homo sapiens_hsa040721.08573911
35Gap junction_Homo sapiens_hsa045401.08435404
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.07570052
37Starch and sucrose metabolism_Homo sapiens_hsa005001.01382357
38Melanoma_Homo sapiens_hsa052181.01107073
39Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99501453
40Basal cell carcinoma_Homo sapiens_hsa052170.96466269
41Caffeine metabolism_Homo sapiens_hsa002320.95959729
42Chronic myeloid leukemia_Homo sapiens_hsa052200.90441200
43Regulation of actin cytoskeleton_Homo sapiens_hsa048100.85227803
44Insulin signaling pathway_Homo sapiens_hsa049100.84458087
45Toxoplasmosis_Homo sapiens_hsa051450.84394961
46Platelet activation_Homo sapiens_hsa046110.84114102
47Phagosome_Homo sapiens_hsa041450.84033139
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83242807
49Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81719716
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.79530751
51MicroRNAs in cancer_Homo sapiens_hsa052060.78803705
52Complement and coagulation cascades_Homo sapiens_hsa046100.78636187
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.78518727
54Ras signaling pathway_Homo sapiens_hsa040140.77364568
55HIF-1 signaling pathway_Homo sapiens_hsa040660.75937937
56Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75653131
57Central carbon metabolism in cancer_Homo sapiens_hsa052300.74777241
58Prion diseases_Homo sapiens_hsa050200.70923856
59Endocytosis_Homo sapiens_hsa041440.70795211
60Staphylococcus aureus infection_Homo sapiens_hsa051500.69913960
61Pathways in cancer_Homo sapiens_hsa052000.68904573
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68846857
63Pancreatic cancer_Homo sapiens_hsa052120.68371904
64Prostate cancer_Homo sapiens_hsa052150.66542644
65Fat digestion and absorption_Homo sapiens_hsa049750.64711210
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64361487
67TNF signaling pathway_Homo sapiens_hsa046680.63552839
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.61597980
69Glioma_Homo sapiens_hsa052140.61234129
70Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59744791
71Hedgehog signaling pathway_Homo sapiens_hsa043400.59579753
72MAPK signaling pathway_Homo sapiens_hsa040100.58610864
73Ovarian steroidogenesis_Homo sapiens_hsa049130.57357214
74Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.57350470
75Dorso-ventral axis formation_Homo sapiens_hsa043200.56529114
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.56164944
77N-Glycan biosynthesis_Homo sapiens_hsa005100.55972830
78Arachidonic acid metabolism_Homo sapiens_hsa005900.55059914
79Pyruvate metabolism_Homo sapiens_hsa006200.54860486
80beta-Alanine metabolism_Homo sapiens_hsa004100.53658657
81Estrogen signaling pathway_Homo sapiens_hsa049150.53255450
82Rap1 signaling pathway_Homo sapiens_hsa040150.53199289
83p53 signaling pathway_Homo sapiens_hsa041150.51788696
84Lysosome_Homo sapiens_hsa041420.50938726
85Tight junction_Homo sapiens_hsa045300.50506589
86GnRH signaling pathway_Homo sapiens_hsa049120.50066099
87Renal cell carcinoma_Homo sapiens_hsa052110.50003141
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.48915868
89Oxytocin signaling pathway_Homo sapiens_hsa049210.48694817
90Calcium signaling pathway_Homo sapiens_hsa040200.48562866
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48154237
92Notch signaling pathway_Homo sapiens_hsa043300.48119933
93Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.46967804
94Galactose metabolism_Homo sapiens_hsa000520.46874980
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.46325772
96Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.45969644
97Glucagon signaling pathway_Homo sapiens_hsa049220.45459072
98Cocaine addiction_Homo sapiens_hsa050300.45160776
99Phenylalanine metabolism_Homo sapiens_hsa003600.44620769
100Osteoclast differentiation_Homo sapiens_hsa043800.44589871
101Renin secretion_Homo sapiens_hsa049240.43946245
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43641712
103Acute myeloid leukemia_Homo sapiens_hsa052210.43641243
104Sulfur metabolism_Homo sapiens_hsa009200.43560021
105Sphingolipid metabolism_Homo sapiens_hsa006000.43521052
106HTLV-I infection_Homo sapiens_hsa051660.43289899
107cAMP signaling pathway_Homo sapiens_hsa040240.43037692
108Thyroid hormone synthesis_Homo sapiens_hsa049180.42478233
109FoxO signaling pathway_Homo sapiens_hsa040680.42074181
110Vibrio cholerae infection_Homo sapiens_hsa051100.41866213
111Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.41697691
112Glycosaminoglycan degradation_Homo sapiens_hsa005310.41210872
113Choline metabolism in cancer_Homo sapiens_hsa052310.40899591
114Other glycan degradation_Homo sapiens_hsa005110.40393737
115Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.40263830
116mTOR signaling pathway_Homo sapiens_hsa041500.40131924
117Leishmaniasis_Homo sapiens_hsa051400.40057908
118Hepatitis B_Homo sapiens_hsa051610.38542595
119Nitrogen metabolism_Homo sapiens_hsa009100.38224407
120Wnt signaling pathway_Homo sapiens_hsa043100.38020049
121Vascular smooth muscle contraction_Homo sapiens_hsa042700.37726153
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36663692
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36624419
124Carbon metabolism_Homo sapiens_hsa012000.36526283
125Renin-angiotensin system_Homo sapiens_hsa046140.36206728
126Pertussis_Homo sapiens_hsa051330.36101184
127Shigellosis_Homo sapiens_hsa051310.35851086
128Melanogenesis_Homo sapiens_hsa049160.35725478
129Pentose and glucuronate interconversions_Homo sapiens_hsa000400.35091031
130Apoptosis_Homo sapiens_hsa042100.34454737
131Sphingolipid signaling pathway_Homo sapiens_hsa040710.33126325
132Tyrosine metabolism_Homo sapiens_hsa003500.32709227
133Lysine degradation_Homo sapiens_hsa003100.32403956

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