CCDC85B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Hepatitis delta virus (HDV) is a pathogenic human virus whose RNA genome and replication cycle resemble those of plant viroids. Delta-interacting protein A (DIPA), a cellular gene product, has been found to have homology to hepatitis delta virus antigen (HDAg). DIPA interacts with the viral antigen, HDAg, and can affect HDV replication in vitro. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.51416511
2deoxyribonucleoside monophosphate metabolic process (GO:0009162)5.44276009
3regulation of synapse structural plasticity (GO:0051823)5.22923010
4locomotory exploration behavior (GO:0035641)5.02107372
5sodium ion export (GO:0071436)4.75615743
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.67854301
7synaptic vesicle docking involved in exocytosis (GO:0016081)4.55690984
8synaptic vesicle exocytosis (GO:0016079)4.55335232
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.42496596
10cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.42156740
11ribosomal small subunit biogenesis (GO:0042274)4.39978728
12regulation of mammary gland epithelial cell proliferation (GO:0033599)4.31727813
13glutamate secretion (GO:0014047)4.31376397
14cell communication by electrical coupling (GO:0010644)4.28229333
15activation of protein kinase A activity (GO:0034199)4.25794561
16regulation of synaptic vesicle exocytosis (GO:2000300)4.13518002
17UV protection (GO:0009650)4.13465849
18positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.10369011
19DNA deamination (GO:0045006)4.08326708
20cellular potassium ion homeostasis (GO:0030007)3.94369317
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.94267369
22neuromuscular process controlling posture (GO:0050884)3.93548765
23regulation of translational termination (GO:0006449)3.92306908
242-deoxyribonucleotide biosynthetic process (GO:0009265)3.82966249
25deoxyribose phosphate biosynthetic process (GO:0046385)3.82966249
26regulation of neuronal synaptic plasticity (GO:0048168)3.82838926
27regulation of synaptic vesicle transport (GO:1902803)3.78306389
28regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.76115516
29regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.75913507
30negative regulation of microtubule polymerization (GO:0031115)3.69336914
31vocalization behavior (GO:0071625)3.68398652
32layer formation in cerebral cortex (GO:0021819)3.68258417
33protein localization to endosome (GO:0036010)3.63887622
34negative regulation of cell size (GO:0045792)3.60034730
35prostaglandin biosynthetic process (GO:0001516)3.58667943
36prostanoid biosynthetic process (GO:0046457)3.58667943
37regulation of long-term neuronal synaptic plasticity (GO:0048169)3.58309580
38exploration behavior (GO:0035640)3.54365813
39regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.53882167
40G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.52919693
41neurotransmitter secretion (GO:0007269)3.51460182
42neuronal action potential propagation (GO:0019227)3.49187113
43nuclear envelope reassembly (GO:0031468)3.45891534
44mitotic nuclear envelope reassembly (GO:0007084)3.45891534
45neuromuscular process controlling balance (GO:0050885)3.40839420
46regulation of glutamate receptor signaling pathway (GO:1900449)3.39611104
47GDP-mannose metabolic process (GO:0019673)3.38938232
48pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.37705045
49positive regulation of synapse maturation (GO:0090129)3.37282002
50regulation of early endosome to late endosome transport (GO:2000641)3.36515331
51positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.33356531
52cerebellar Purkinje cell layer development (GO:0021680)3.32108486
53negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.27201770
54pinocytosis (GO:0006907)3.24984107
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.21481519
56potassium ion export (GO:0071435)3.19878051
57regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.18541318
58protein localization to synapse (GO:0035418)3.17701948
59negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.13357184
60nucleobase-containing small molecule interconversion (GO:0015949)3.12172756
61response to pheromone (GO:0019236)3.10677781
62protein retention in ER lumen (GO:0006621)3.09672819
63stress fiber assembly (GO:0043149)3.02657848
64proline biosynthetic process (GO:0006561)3.02601730
65plasma membrane repair (GO:0001778)3.02567460
66response to gravity (GO:0009629)3.01980655
67positive regulation of fibroblast migration (GO:0010763)3.00946106
68activation of MAPKKK activity (GO:0000185)3.00834955
69peptidyl-arginine omega-N-methylation (GO:0035247)3.00063025
70negative regulation of erythrocyte differentiation (GO:0045647)2.99428912
71viral transcription (GO:0019083)2.99280838
72barbed-end actin filament capping (GO:0051016)2.98891694
73guanosine-containing compound biosynthetic process (GO:1901070)2.98769182
74signal complex assembly (GO:0007172)2.95693732
75positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.95320163
76positive regulation of synaptic transmission, GABAergic (GO:0032230)2.94151094
77regulation of ARF GTPase activity (GO:0032312)2.93774291
78regulation of glucocorticoid metabolic process (GO:0031943)2.93146340
79cell communication involved in cardiac conduction (GO:0086065)2.92610344
80pyrimidine nucleotide catabolic process (GO:0006244)2.90564285
81potassium ion import (GO:0010107)2.88659143
82dopamine receptor signaling pathway (GO:0007212)2.87540339
83modulation by virus of host process (GO:0019054)2.87247096
84cellular sodium ion homeostasis (GO:0006883)2.87212422
85regulation of apoptotic process involved in morphogenesis (GO:1902337)2.86707401
86cytoskeletal anchoring at plasma membrane (GO:0007016)2.85850448
87antigen processing and presentation via MHC class Ib (GO:0002475)2.84054819
88protein targeting to plasma membrane (GO:0072661)2.83820873
89mitotic G1 DNA damage checkpoint (GO:0031571)2.82740911
90focal adhesion assembly (GO:0048041)2.82121019
91cell-substrate adherens junction assembly (GO:0007045)2.82121019
92regulation of ARF protein signal transduction (GO:0032012)2.81886027
93negative regulation of B cell apoptotic process (GO:0002903)2.81061739
94positive regulation of protein dephosphorylation (GO:0035307)2.79589863
95regulation of defense response to virus by virus (GO:0050690)2.79292872
96regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.78551308
97membrane repolarization (GO:0086009)2.78238137
98activation of Rac GTPase activity (GO:0032863)2.78145698
99axon cargo transport (GO:0008088)2.77406391
100negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.75568495
101cAMP biosynthetic process (GO:0006171)2.74841918
102maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.74102059
103positive regulation of lamellipodium assembly (GO:0010592)2.73808239
104pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.72868586
105modulation by symbiont of host cellular process (GO:0044068)2.71581403
106protein maturation by protein folding (GO:0022417)2.70408181
107positive regulation of potassium ion transmembrane transport (GO:1901381)2.70406010
108growth hormone secretion (GO:0030252)2.69903308
109regulation of synaptic plasticity (GO:0048167)2.69858691
110positive regulation of axon extension (GO:0045773)2.68937440
111apoptotic process involved in morphogenesis (GO:0060561)2.68707597
112positive regulation of membrane potential (GO:0045838)2.68393322
113deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.67178105
114glycine transport (GO:0015816)2.66455548
115deoxyribonucleotide catabolic process (GO:0009264)2.65959641
116mature B cell differentiation involved in immune response (GO:0002313)2.65673946
117adherens junction assembly (GO:0034333)2.65020569
118adenine nucleotide transport (GO:0051503)2.64776802
119adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.64422717
120mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.63778697
121translational termination (GO:0006415)2.62651694
122positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.62548214
123dendritic spine morphogenesis (GO:0060997)2.61842871
124membrane depolarization during action potential (GO:0086010)2.61840733
125regulation of sodium ion transmembrane transporter activity (GO:2000649)2.61776572
126positive regulation of blood vessel endothelial cell migration (GO:0043536)2.61071211
127potassium ion homeostasis (GO:0055075)2.60583524
128nucleotide salvage (GO:0043173)2.59469953
129translational elongation (GO:0006414)2.59406253
130regulation of membrane repolarization (GO:0060306)2.59339468
131adenosine receptor signaling pathway (GO:0001973)2.59106071
132vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.56942142
133proline transport (GO:0015824)2.56884577
134protein heterotrimerization (GO:0070208)2.56148012
135negative regulation of cytosolic calcium ion concentration (GO:0051481)2.55793182
136positive regulation of protein sumoylation (GO:0033235)2.55717216
137purine deoxyribonucleotide catabolic process (GO:0009155)2.55716974
138nucleoside diphosphate biosynthetic process (GO:0009133)2.55343315
139adhesion of symbiont to host (GO:0044406)2.55098447
140angiogenesis involved in wound healing (GO:0060055)2.55060099
141endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.54447587
142regulation of necrotic cell death (GO:0010939)2.53880134
143regulation of calcium ion transmembrane transporter activity (GO:1901019)2.53563231
144regulation of calcium ion transmembrane transport (GO:1903169)2.53563231
145adhesion of symbiont to host cell (GO:0044650)2.53465495
146virion attachment to host cell (GO:0019062)2.53465495
147protein insertion into membrane (GO:0051205)2.53216545
148positive regulation of dendritic spine development (GO:0060999)2.51290215
149neurotransmitter-gated ion channel clustering (GO:0072578)2.51121771
150histone arginine methylation (GO:0034969)2.50187525
151regulation of dendritic spine morphogenesis (GO:0061001)2.49914367
152establishment of nucleus localization (GO:0040023)2.49606002
153deoxyribose phosphate catabolic process (GO:0046386)2.47968656
154prepulse inhibition (GO:0060134)2.46168377
155glucose catabolic process (GO:0006007)2.44975753
156Golgi transport vesicle coating (GO:0048200)2.44753101
157COPI coating of Golgi vesicle (GO:0048205)2.44753101
158type B pancreatic cell proliferation (GO:0044342)2.44087984
159UTP biosynthetic process (GO:0006228)2.44059970
160platelet aggregation (GO:0070527)2.43827700
161deoxyribonucleotide biosynthetic process (GO:0009263)2.43379610
162response to auditory stimulus (GO:0010996)2.42654356
163regulation of voltage-gated calcium channel activity (GO:1901385)2.42641848
164regulation of ion transmembrane transporter activity (GO:0032412)2.42247763
165retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.42244530
166pentose-phosphate shunt (GO:0006098)2.41974472
167lipopolysaccharide biosynthetic process (GO:0009103)2.41383709
168pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.41114499
169cell-substrate junction assembly (GO:0007044)2.39831310
170modulation by virus of host morphology or physiology (GO:0019048)2.38249157
171maturation of SSU-rRNA (GO:0030490)2.37468178
172chaperone mediated protein folding requiring cofactor (GO:0051085)2.37306166
173positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.36579894
174regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.36579894
175peptidyl-proline hydroxylation (GO:0019511)2.36086444
176regulation of mitochondrial membrane potential (GO:0051881)2.35237548
177viral life cycle (GO:0019058)2.35164643
1782-deoxyribonucleotide metabolic process (GO:0009394)2.35106002
179negative regulation of necrotic cell death (GO:0060547)2.33646778
180cell migration involved in heart development (GO:0060973)2.31658825

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* LXR_22292898_ChIP-Seq_THP-1_Human2.86599569
2MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.85584746
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.80954923
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.70513677
5* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.65129570
6ZNF263_19887448_ChIP-Seq_K562_Human2.56141826
7MYC_22102868_ChIP-Seq_BL_Human2.54775003
8ZFP281_18757296_ChIP-ChIP_E14_Mouse2.39538628
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.35073892
10* RARB_27405468_Chip-Seq_BRAIN_Mouse2.28282860
11* KDM2B_26808549_Chip-Seq_DND41_Human2.25999528
12* ELK3_25401928_ChIP-Seq_HUVEC_Human2.25180744
13VDR_21846776_ChIP-Seq_THP-1_Human2.21343394
14ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.20322714
15PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.09350872
16DNAJC2_21179169_ChIP-ChIP_NT2_Human2.08417799
17CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.04068231
18KDM2B_26808549_Chip-Seq_K562_Human1.99306795
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.97755271
20EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.96623725
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.96409101
22IKZF1_21737484_ChIP-ChIP_HCT116_Human1.95501628
23EZH2_22144423_ChIP-Seq_EOC_Human1.88084373
24TP63_17297297_ChIP-ChIP_HaCaT_Human1.86615322
25TCF7_22412390_ChIP-Seq_EML_Mouse1.81874255
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.81421081
27ERG_21242973_ChIP-ChIP_JURKAT_Human1.80453966
28TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.77939957
29ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.77102232
30NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.74144040
31ELF1_20517297_ChIP-Seq_JURKAT_Human1.72655795
32TET1_21451524_ChIP-Seq_MESCs_Mouse1.72612646
33P68_20966046_ChIP-Seq_HELA_Human1.72145808
34SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.71351412
35* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.67690737
36* RACK7_27058665_Chip-Seq_MCF-7_Human1.63675476
37DROSHA_22980978_ChIP-Seq_HELA_Human1.63052186
38* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.61604387
39SRY_22984422_ChIP-ChIP_TESTIS_Rat1.59894277
40CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.58520409
41* MYC_18555785_ChIP-Seq_MESCs_Mouse1.58061431
42* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.56191433
43CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.55640981
44WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.55127093
45SA1_27219007_Chip-Seq_ERYTHROID_Human1.55119991
46REST_18959480_ChIP-ChIP_MESCs_Mouse1.54391329
47BCL6_27268052_Chip-Seq_Bcells_Human1.54159186
48ZFP281_27345836_Chip-Seq_ESCs_Mouse1.51544428
49SMC4_20622854_ChIP-Seq_HELA_Human1.50190143
50UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.47873113
51XRN2_22483619_ChIP-Seq_HELA_Human1.47280513
52* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.46612707
53* KDM2B_26808549_Chip-Seq_JURKAT_Human1.46324360
54GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.45338502
55SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.45192315
56RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.44451256
57CTCF_27219007_Chip-Seq_Bcells_Human1.41473784
58JARID2_20075857_ChIP-Seq_MESCs_Mouse1.38546816
59CTCF_27219007_Chip-Seq_ERYTHROID_Human1.37412702
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35384183
61JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.35302422
62CREB1_26743006_Chip-Seq_LNCaP_Human1.35124865
63BCOR_27268052_Chip-Seq_Bcells_Human1.34103239
64REST_21632747_ChIP-Seq_MESCs_Mouse1.31977850
65MTF2_20144788_ChIP-Seq_MESCs_Mouse1.31808332
66SUZ12_27294783_Chip-Seq_ESCs_Mouse1.31563836
67* TP53_22127205_ChIP-Seq_IMR90_Human1.30487455
68THAP11_20581084_ChIP-Seq_MESCs_Mouse1.30244697
69TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.29191312
70SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.28569609
71* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.27121751
72TET1_21490601_ChIP-Seq_MESCs_Mouse1.26349962
73* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.25865162
74SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25618728
75CTCF_18555785_ChIP-Seq_MESCs_Mouse1.25307751
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.24953542
77MYC_19079543_ChIP-ChIP_MESCs_Mouse1.23935656
78RNF2_18974828_ChIP-Seq_MESCs_Mouse1.23271936
79EZH2_18974828_ChIP-Seq_MESCs_Mouse1.23271936
80* FOXP1_21924763_ChIP-Seq_HESCs_Human1.22954170
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.22496254
82CTCF_26484167_Chip-Seq_Bcells_Mouse1.22183460
83SPI1_23127762_ChIP-Seq_K562_Human1.21976329
84SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.21632106
85ATF3_27146783_Chip-Seq_COLON_Human1.20558561
86ESR2_21235772_ChIP-Seq_MCF-7_Human1.20070148
87TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.20013088
88NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.19728068
89EZH2_27294783_Chip-Seq_ESCs_Mouse1.19490561
90* MAF_26560356_Chip-Seq_TH1_Human1.18883363
91RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.18781776
92PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.18064862
93TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.17614698
94PHF8_20622854_ChIP-Seq_HELA_Human1.17011422
95UTX_26944678_Chip-Seq_JUKART_Human1.16584156
96VDR_24763502_ChIP-Seq_THP-1_Human1.16448700
97PU.1_20513432_ChIP-Seq_Bcells_Mouse1.16052876
98SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.15906546
99SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15243100
100CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.14153975
101YY1_22570637_ChIP-Seq_MALME-3M_Human1.14070967
102RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.14007366
103JARID2_20064375_ChIP-Seq_MESCs_Mouse1.13738465
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.12717573
105KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12418231
106* CTCF_21964334_Chip-Seq_Bcells_Human1.12309034
107PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.11557363
108* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.11499693
109TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11466542
110FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.11244103
111MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.10408484
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10166149
113RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09868311
114MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.09633229
115SMC3_22415368_ChIP-Seq_MEFs_Mouse1.09429666
116* SA1_27219007_Chip-Seq_Bcells_Human1.09183295
117RUNX1_22412390_ChIP-Seq_EML_Mouse1.08463711
118SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.07840732
119RARA_24833708_ChIP-Seq_LIVER_Mouse1.07615732
120SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.07596363
121KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07581575
122TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07242036
123ZFX_18555785_ChIP-Seq_MESCs_Mouse1.07194022
124E2F1_20622854_ChIP-Seq_HELA_Human1.06589835
125NCOR1_26117541_ChIP-Seq_K562_Human1.06576712
126P300_27058665_Chip-Seq_ZR-75-30cells_Human1.05806967
127SMC1_22415368_ChIP-Seq_MEFs_Mouse1.05535996
128GATA1_19941827_ChIP-Seq_MEL_Mouse1.04444512
129SPI1_20517297_ChIP-Seq_HL60_Human1.04298017
130* MAF_26560356_Chip-Seq_TH2_Human1.03967531
131ETS1_21867929_ChIP-Seq_TH2_Mouse1.03162516
132* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.02552412
133GATA1_22383799_ChIP-Seq_G1ME_Mouse0.99928607
134MYC_19030024_ChIP-ChIP_MESCs_Mouse0.98725764
135* CTCF_20526341_ChIP-Seq_ESCs_Human0.98500600

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.48531616
2MP0008438_abnormal_cutaneous_collagen3.44884702
3MP0003635_abnormal_synaptic_transmissio3.34505941
4MP0002909_abnormal_adrenal_gland2.95688719
5MP0005451_abnormal_body_composition2.93090508
6MP0004858_abnormal_nervous_system2.88338704
7MP0000751_myopathy2.75871190
8MP0002877_abnormal_melanocyte_morpholog2.62296616
9MP0004270_analgesia2.54759478
10MP0002063_abnormal_learning/memory/cond2.47397981
11MP0003329_amyloid_beta_deposits2.46649311
12MP0008961_abnormal_basal_metabolism2.39265007
13MP0002822_catalepsy2.38631806
14MP0005167_abnormal_blood-brain_barrier2.18789326
15MP0000013_abnormal_adipose_tissue2.12935972
16MP0002064_seizures2.11968151
17MP0001968_abnormal_touch/_nociception2.09725677
18MP0009745_abnormal_behavioral_response2.04374621
19MP0003075_altered_response_to1.96074734
20MP0002089_abnormal_postnatal_growth/wei1.94422293
21MP0003191_abnormal_cellular_cholesterol1.91636323
22MP0003880_abnormal_central_pattern1.88384567
23MP0009379_abnormal_foot_pigmentation1.86731388
24MP0004811_abnormal_neuron_physiology1.85552765
25MP0003705_abnormal_hypodermis_morpholog1.80734855
26MP0001542_abnormal_bone_strength1.80442275
27MP0008569_lethality_at_weaning1.74842373
28MP0003566_abnormal_cell_adhesion1.74827660
29MP0004130_abnormal_muscle_cell1.72769718
30MP0010368_abnormal_lymphatic_system1.70485506
31MP0002733_abnormal_thermal_nociception1.69532674
32MP0002736_abnormal_nociception_after1.66572276
33MP0003172_abnormal_lysosome_physiology1.64974981
34MP0004185_abnormal_adipocyte_glucose1.63630846
35MP0003283_abnormal_digestive_organ1.63067222
36MP0003436_decreased_susceptibility_to1.62216968
37MP0009046_muscle_twitch1.61027854
38MP0003279_aneurysm1.60036521
39MP0010030_abnormal_orbit_morphology1.58205485
40MP0000678_abnormal_parathyroid_gland1.57897589
41MP0001348_abnormal_lacrimal_gland1.56706377
42MP0002272_abnormal_nervous_system1.55870602
43MP0000681_abnormal_thyroid_gland1.54138354
44MP0001970_abnormal_pain_threshold1.53337788
45MP0002572_abnormal_emotion/affect_behav1.53069638
46MP0005464_abnormal_platelet_physiology1.51326805
47MP0000749_muscle_degeneration1.50502235
48MP0004145_abnormal_muscle_electrophysio1.48639343
49MP0004084_abnormal_cardiac_muscle1.46794720
50MP0003879_abnormal_hair_cell1.46257415
51MP0002269_muscular_atrophy1.45974833
52MP0002734_abnormal_mechanical_nocicepti1.44410878
53MP0002735_abnormal_chemical_nociception1.44121860
54MP0000747_muscle_weakness1.42815092
55MP0005423_abnormal_somatic_nervous1.40743440
56MP0000858_altered_metastatic_potential1.40720796
57MP0005257_abnormal_intraocular_pressure1.38609797
58MP0003303_peritoneal_inflammation1.37814113
59MP0003137_abnormal_impulse_conducting1.37697397
60MP0004215_abnormal_myocardial_fiber1.36349009
61MP0009384_cardiac_valve_regurgitation1.35766210
62MP0003633_abnormal_nervous_system1.34329261
63MP0008260_abnormal_autophagy1.34297324
64MP0004272_abnormal_basement_membrane1.34100812
65MP0000750_abnormal_muscle_regeneration1.31448965
66MP0004233_abnormal_muscle_weight1.30973363
67MP0000343_altered_response_to1.30550414
68MP0005330_cardiomyopathy1.29332296
69MP0005501_abnormal_skin_physiology1.28546118
70MP0000955_abnormal_spinal_cord1.25094472
71MP0000733_abnormal_muscle_development1.24939067
72MP0003091_abnormal_cell_migration1.21992735
73MP0009333_abnormal_splenocyte_physiolog1.20909944
74MP0005375_adipose_tissue_phenotype1.18651791
75MP0004087_abnormal_muscle_fiber1.16852792
76MP0000604_amyloidosis1.16639152
77MP0005023_abnormal_wound_healing1.13247860
78MP0002184_abnormal_innervation1.12161933
79MP0001958_emphysema1.11558250
80MP0004036_abnormal_muscle_relaxation1.11340864
81MP0000759_abnormal_skeletal_muscle1.10283489
82MP0003123_paternal_imprinting1.07980706
83MP0009780_abnormal_chondrocyte_physiolo1.07470171
84MP0005076_abnormal_cell_differentiation1.06809257
85MP0008874_decreased_physiological_sensi1.05786006
86MP0005508_abnormal_skeleton_morphology1.05495164
87MP0005058_abnormal_lysosome_morphology1.03976595
88MP0001486_abnormal_startle_reflex1.03822102
89MP0001984_abnormal_olfaction1.01572371
90MP0002060_abnormal_skin_morphology1.01511725
91MP0003122_maternal_imprinting1.01262546
92MP0004510_myositis1.01060558
93MP0000767_abnormal_smooth_muscle1.00701233
94MP0002067_abnormal_sensory_capabilities1.00555903
95MP0005390_skeleton_phenotype1.00301791
96MP0005503_abnormal_tendon_morphology0.99992403
97MP0004085_abnormal_heartbeat0.99791572
98MP0009278_abnormal_bone_marrow0.99574579
99MP0002066_abnormal_motor_capabilities/c0.99452984
100MP0002249_abnormal_larynx_morphology0.97695093
101MP0005623_abnormal_meninges_morphology0.95986340
102MP0003763_abnormal_thymus_physiology0.95762004
103MP0004947_skin_inflammation0.95582039
104MP0001501_abnormal_sleep_pattern0.95529071
105MP0001905_abnormal_dopamine_level0.94064191
106MP0002106_abnormal_muscle_physiology0.93865321
107MP0001502_abnormal_circadian_rhythm0.92817575
108MP0002557_abnormal_social/conspecific_i0.92571862
109MP0000685_abnormal_immune_system0.91005099
110MP0004142_abnormal_muscle_tone0.90971024
111MP0005666_abnormal_adipose_tissue0.89764110
112MP0005621_abnormal_cell_physiology0.88534565
113MP0001533_abnormal_skeleton_physiology0.86958551
114MP0009840_abnormal_foam_cell0.85814171
115MP0000490_abnormal_crypts_of0.85169938
116MP0002837_dystrophic_cardiac_calcinosis0.84790701
117MP0000003_abnormal_adipose_tissue0.84625808
118MP0005165_increased_susceptibility_to0.84483681
119MP0001243_abnormal_dermal_layer0.83432883
120MP0005385_cardiovascular_system_phenoty0.81314882
121MP0001544_abnormal_cardiovascular_syste0.81314882
122MP0002396_abnormal_hematopoietic_system0.80892175
123MP0005166_decreased_susceptibility_to0.80728222
124MP0005386_behavior/neurological_phenoty0.80676289
125MP0004924_abnormal_behavior0.80676289
126MP0009053_abnormal_anal_canal0.80387759
127MP0005397_hematopoietic_system_phenotyp0.80291067
128MP0001545_abnormal_hematopoietic_system0.80291067
129MP0003631_nervous_system_phenotype0.79571636
130MP0008872_abnormal_physiological_respon0.79463656
131MP0005595_abnormal_vascular_smooth0.78261694
132MP0008770_decreased_survivor_rate0.77316710
133MP0005083_abnormal_biliary_tract0.77170486
134MP0004808_abnormal_hematopoietic_stem0.76866094
135MP0003634_abnormal_glial_cell0.75296387
136MP0002882_abnormal_neuron_morphology0.75225119
137MP0003453_abnormal_keratinocyte_physiol0.75217355
138MP0003186_abnormal_redox_activity0.75057928
139MP0002933_joint_inflammation0.73940713
140MP0005670_abnormal_white_adipose0.73872758
141MP0003300_gastrointestinal_ulcer0.73522610
142MP0001879_abnormal_lymphatic_vessel0.72634064
143MP0001849_ear_inflammation0.72566969
144MP0005000_abnormal_immune_tolerance0.72440300
145MP0006036_abnormal_mitochondrial_physio0.71741497
146MP0002398_abnormal_bone_marrow0.71450751
147MP0001440_abnormal_grooming_behavior0.71116531
148MP0003866_abnormal_defecation0.70963168
149MP0003448_altered_tumor_morphology0.70936122
150MP0000358_abnormal_cell_content/0.70324804
151MP0005620_abnormal_muscle_contractility0.68930037
152MP0002796_impaired_skin_barrier0.68253534
153MP0002148_abnormal_hypersensitivity_rea0.67530549
154MP0002234_abnormal_pharynx_morphology0.67434247
155MP0001661_extended_life_span0.65770358
156MP0005025_abnormal_response_to0.65176252
157MP0002429_abnormal_blood_cell0.64733779
158MP0002295_abnormal_pulmonary_circulatio0.63647933
159MP0010771_integument_phenotype0.63358902

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.40825472
2Visual hallucinations (HP:0002367)4.20376436
3Premature rupture of membranes (HP:0001788)4.12518171
4Annular pancreas (HP:0001734)3.96084238
5Vertebral compression fractures (HP:0002953)3.93324665
6Abnormality of the lower motor neuron (HP:0002366)3.62046371
7Ventricular fibrillation (HP:0001663)3.53951066
8Insomnia (HP:0100785)3.50510783
9Hyperacusis (HP:0010780)3.36768670
10Spinal canal stenosis (HP:0003416)3.20352010
11Distal lower limb amyotrophy (HP:0008944)3.06468427
12Ankle clonus (HP:0011448)3.05441113
13Distal lower limb muscle weakness (HP:0009053)3.00305741
14Protrusio acetabuli (HP:0003179)2.99016621
15Depression (HP:0000716)2.98034716
16Focal motor seizures (HP:0011153)2.97719983
17Cerebral aneurysm (HP:0004944)2.93547233
18Spinal rigidity (HP:0003306)2.86742819
19Pointed chin (HP:0000307)2.86107370
20Supranuclear gaze palsy (HP:0000605)2.84963306
21Ankle contracture (HP:0006466)2.82356852
22Focal seizures (HP:0007359)2.81794898
23Cellulitis (HP:0100658)2.81505734
24Fragile skin (HP:0001030)2.76931040
25Difficulty climbing stairs (HP:0003551)2.71473902
26Distal upper limb amyotrophy (HP:0007149)2.71234436
27Upper limb amyotrophy (HP:0009129)2.71234436
28Hemiplegia (HP:0002301)2.70908479
29Hypercortisolism (HP:0001578)2.70765934
30Bundle branch block (HP:0011710)2.68367245
31Myotonia (HP:0002486)2.66875271
32Achilles tendon contracture (HP:0001771)2.66137323
33Growth hormone excess (HP:0000845)2.63787194
34Generalized amyotrophy (HP:0003700)2.63258226
35Increased connective tissue (HP:0009025)2.62753460
36Elbow flexion contracture (HP:0002987)2.62077745
37Torticollis (HP:0000473)2.59827880
38Papilledema (HP:0001085)2.59346152
39Broad metatarsal (HP:0001783)2.59297955
40Polygenic inheritance (HP:0010982)2.55568263
41Stridor (HP:0010307)2.52755044
42Action tremor (HP:0002345)2.52163936
43Focal dystonia (HP:0004373)2.49137664
44Type 1 muscle fiber predominance (HP:0003803)2.47664348
45Large eyes (HP:0001090)2.47458301
46Hypertensive crisis (HP:0100735)2.42815427
47Mitral regurgitation (HP:0001653)2.42348785
48Lower limb amyotrophy (HP:0007210)2.40302710
49Craniofacial dystonia (HP:0012179)2.40176383
50Ulnar bowing (HP:0003031)2.39215278
51Obstructive sleep apnea (HP:0002870)2.38074495
52Abnormality of the Achilles tendon (HP:0005109)2.38026365
53Testicular atrophy (HP:0000029)2.37785637
54Elfin facies (HP:0004428)2.37180988
55Joint stiffness (HP:0001387)2.33942773
56Anxiety (HP:0000739)2.33134154
57Abnormal EKG (HP:0003115)2.32713288
58Premature skin wrinkling (HP:0100678)2.31436625
59Long toe (HP:0010511)2.30212359
60Rapidly progressive (HP:0003678)2.28425084
61Biconcave vertebral bodies (HP:0004586)2.28211433
62Slender build (HP:0001533)2.26619710
63Broad distal phalanx of finger (HP:0009836)2.26504914
64Hand muscle atrophy (HP:0009130)2.24085811
65Cervical subluxation (HP:0003308)2.23485640
66Exercise-induced myalgia (HP:0003738)2.22904819
67Ragged-red muscle fibers (HP:0003200)2.21836176
68Mildly elevated creatine phosphokinase (HP:0008180)2.21783044
69Poor eye contact (HP:0000817)2.20331916
70Reduced subcutaneous adipose tissue (HP:0003758)2.19889091
71Rough bone trabeculation (HP:0100670)2.18548222
72Sudden death (HP:0001699)2.15945399
73Wormian bones (HP:0002645)2.14653766
74Genu recurvatum (HP:0002816)2.14430431
75Striae distensae (HP:0001065)2.12561835
76Bowel diverticulosis (HP:0005222)2.11737969
77Increased variability in muscle fiber diameter (HP:0003557)2.10464548
78Centrally nucleated skeletal muscle fibers (HP:0003687)2.10402222
79Myoglobinuria (HP:0002913)2.10392401
80Polycythemia (HP:0001901)2.09326401
81Limb-girdle muscle atrophy (HP:0003797)2.07859671
82Renal duplication (HP:0000075)2.07455119
83Neoplasm of the heart (HP:0100544)2.06807344
84Urinary urgency (HP:0000012)2.05431773
85Absence seizures (HP:0002121)2.03927023
86Abnormality of pain sensation (HP:0010832)2.03862460
87Impaired pain sensation (HP:0007328)2.03862460
88Diminished motivation (HP:0000745)2.03710832
89Pheochromocytoma (HP:0002666)2.03651519
90Axonal loss (HP:0003447)2.03435820
91Agammaglobulinemia (HP:0004432)2.01482478
92Blue sclerae (HP:0000592)2.01241596
93Neoplasm of the peripheral nervous system (HP:0100007)2.00316287
94Mutism (HP:0002300)1.99807341
95Bladder diverticulum (HP:0000015)1.99339105
96Heart block (HP:0012722)1.99202204
97Abnormal social behavior (HP:0012433)1.99103927
98Impaired social interactions (HP:0000735)1.99103927
99Unsteady gait (HP:0002317)1.97619043
100Menstrual irregularities (HP:0000858)1.97420243
101Apathy (HP:0000741)1.96714091
102Overriding aorta (HP:0002623)1.96028218
103Atrioventricular block (HP:0001678)1.95902066
104Hyperthyroidism (HP:0000836)1.95337761
105Prolonged QT interval (HP:0001657)1.95064010
106Abnormal atrioventricular conduction (HP:0005150)1.94748009
107Atrophic scars (HP:0001075)1.93667900
108Short nail (HP:0001799)1.92148350
109Truncus arteriosus (HP:0001660)1.91973857
110J-shaped sella turcica (HP:0002680)1.91080224
111Deep palmar crease (HP:0006191)1.90506985
112Petechiae (HP:0000967)1.90049323
113Abnormal eating behavior (HP:0100738)1.89825865
114Radial bowing (HP:0002986)1.89792815
115Broad face (HP:0000283)1.89608711
116Megalencephaly (HP:0001355)1.89603142
117Enlarged penis (HP:0000040)1.89399170
118Trismus (HP:0000211)1.87447696
119Emphysema (HP:0002097)1.87338728
120Abnormality of skeletal muscle fiber size (HP:0012084)1.86390811
121Delusions (HP:0000746)1.84540956
122Long palpebral fissure (HP:0000637)1.84311201
123Abnormality of the vocal cords (HP:0008777)1.84257548
124Hyperparathyroidism (HP:0000843)1.84219545
125Facial edema (HP:0000282)1.83842321
126Neuroendocrine neoplasm (HP:0100634)1.83562924
127Difficulty running (HP:0009046)1.83096174
128Microretrognathia (HP:0000308)1.81990586
129Acanthosis nigricans (HP:0000956)1.81222583
130Impaired vibration sensation in the lower limbs (HP:0002166)1.80777593
131Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.80679824
132Abnormality of alanine metabolism (HP:0010916)1.80679824
133Hyperalaninemia (HP:0003348)1.80679824
134Myopathic facies (HP:0002058)1.80524896
135Bradykinesia (HP:0002067)1.79174152
136Gastrointestinal stroma tumor (HP:0100723)1.78737309
137Progressive muscle weakness (HP:0003323)1.78602281
138Periorbital edema (HP:0100539)1.78512285
139Ventricular arrhythmia (HP:0004308)1.78236834
140Short clavicles (HP:0000894)1.78147094
141Nonimmune hydrops fetalis (HP:0001790)1.78002185
142Redundant skin (HP:0001582)1.77403966
143Asymmetric septal hypertrophy (HP:0001670)1.77164045
144Purpura (HP:0000979)1.76718864
145Abnormality of the umbilical cord (HP:0010881)1.76666900
146Fatigue (HP:0012378)1.76357485
147Renovascular hypertension (HP:0100817)1.76237628
148Hypoventilation (HP:0002791)1.75009885
149Bulbar palsy (HP:0001283)1.74440522
150Palpitations (HP:0001962)1.74136670
151Increased muscle lipid content (HP:0009058)1.74011690
152Insulin resistance (HP:0000855)1.72999143
153Hydroureter (HP:0000072)1.72373878
154Dysostosis multiplex (HP:0000943)1.72373094
155Atonic seizures (HP:0010819)1.72116954
156Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71700746
157Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71700746
158Stereotypic behavior (HP:0000733)1.71559797
159Cerebral inclusion bodies (HP:0100314)1.70993673
160Postural instability (HP:0002172)1.70427707
161Shallow orbits (HP:0000586)1.70286615
162Flat cornea (HP:0007720)1.69768948
163Abnormality of dentin (HP:0010299)1.67633654
164Prolonged neonatal jaundice (HP:0006579)1.65523063
165Disproportionate tall stature (HP:0001519)1.65390928
166Abnormality of the tricuspid valve (HP:0001702)1.65360742
167Chronic obstructive pulmonary disease (HP:0006510)1.64299391
168Obstructive lung disease (HP:0006536)1.64299391
169Hypertriglyceridemia (HP:0002155)1.63992556
170Muscle stiffness (HP:0003552)1.63802826
171Increased intramyocellular lipid droplets (HP:0012240)1.63008194
172Aortic aneurysm (HP:0004942)1.62938747
173Patellar dislocation (HP:0002999)1.62315352

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.01352844
2TRIB33.63618771
3MAP3K92.90916486
4IRAK32.82886266
5SMG12.77306465
6PKN22.63580110
7KSR22.56057130
8MAPKAPK32.49407031
9SCYL22.44210631
10VRK22.30910277
11PRPF4B2.27232287
12EPHA42.26301836
13KDR2.21972161
14TAOK22.17988352
15CAMKK12.16707548
16MAP3K112.16254362
17PAK62.09637037
18PRKD32.07658982
19MINK12.00023070
20NTRK31.93986609
21TAOK11.88317433
22LMTK21.86600404
23CDK191.85015992
24DAPK11.82448033
25ARAF1.79436794
26EEF2K1.77617076
27RIPK11.70071453
28ERN11.64439751
29NEK11.62569576
30ABL21.59456845
31MAP2K31.55229098
32EPHA21.49408764
33DAPK21.49031691
34MAP3K121.43096468
35CAMKK21.42871997
36TESK21.35946204
37SIK21.31316461
38NTRK11.30402858
39BRAF1.29956712
40PHKG11.23366689
41PHKG21.23366689
42GRK51.23341743
43LATS21.22848624
44RAF11.20284597
45KSR11.19348134
46TYRO31.19077819
47PINK11.15274972
48PDGFRA1.09790518
49TIE11.08335451
50TBK11.08148159
51MAP3K11.07814832
52CDK51.05926706
53LRRK21.04953402
54MAP3K101.04821247
55CDK81.03820147
56CAMK11.02259345
57STK380.99918155
58IRAK20.99226540
59TESK10.99186669
60LIMK10.98230544
61TNK20.97851343
62NTRK20.96231243
63RET0.94859598
64TTN0.89389369
65AURKA0.89135427
66DAPK30.88669452
67BCKDK0.87108418
68MAP4K10.85584819
69CDK150.85402314
70CDK180.84921344
71UHMK10.83857326
72ALK0.83446501
73CDK11A0.82692352
74DDR20.80890013
75CDK140.80676220
76FES0.80198424
77PRKCH0.80005995
78PRKG20.79028943
79IRAK40.78718612
80MARK20.78223637
81PTK2B0.77704906
82MAPK110.75754202
83PAK10.74902631
84MAP3K130.74610948
85ICK0.73237606
86MAP2K10.72148116
87MAP2K40.71832010
88MOS0.70770935
89CAMK2G0.69990203
90BUB10.69870224
91ILK0.69506870
92MAP3K70.68306057
93MAP3K30.66630524
94ZAP700.64600853
95EPHB20.64167940
96MYLK0.64038080
97RPS6KA20.61765447
98BMX0.61152104
99FLT30.60577084
100BRSK10.60478683
101PAK30.60272758
102MAP3K80.59431713
103MARK10.58676781
104MAP3K20.57385660
105MAPK120.56031212
106PDK10.55948282
107PAK20.55194675
108GRK60.54795859
109RPS6KC10.54065821
110RPS6KL10.54065821
111PIM20.53203849
112PTK60.52881725
113MAPK40.51908555
114CAMK2B0.51829075
115CAMK40.51000727
116SIK30.50333918
117MST1R0.49438472
118PDPK10.48416413
119PRKCG0.47681305
120MAP2K60.47425562
121PRKCI0.47242470
122MAP3K40.46949410
123MTOR0.46245868
124MUSK0.46031446
125PAK40.45725537
126PRKD20.44763779
127ROCK20.44489168
128HIPK20.44333818
129TGFBR20.44094948
130CDK70.44018805
131RIPK40.43687107
132PTK20.43424756
133MATK0.42555325
134RPS6KB20.40845449
135DMPK0.38607276
136SIK10.37758287
137MAP2K20.37728074
138PRKD10.36930770
139RPS6KA60.36251620
140CDC42BPA0.35863416

Predicted pathways (KEGG)

RankGene SetZ-score
1Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.89884611
2Synaptic vesicle cycle_Homo sapiens_hsa047212.73882197
3Olfactory transduction_Homo sapiens_hsa047402.59362837
4Ribosome_Homo sapiens_hsa030102.57229962
5Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.99395641
6Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.97380287
7Glycosaminoglycan degradation_Homo sapiens_hsa005311.96191887
8Circadian entrainment_Homo sapiens_hsa047131.95467118
9Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.95160324
10Base excision repair_Homo sapiens_hsa034101.94849456
11Long-term potentiation_Homo sapiens_hsa047201.90716144
12Pentose phosphate pathway_Homo sapiens_hsa000301.90673061
13DNA replication_Homo sapiens_hsa030301.89823251
14Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.88503723
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.87339151
16Other glycan degradation_Homo sapiens_hsa005111.80498665
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.79460029
18Amphetamine addiction_Homo sapiens_hsa050311.68567385
19Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.67005694
20Pyrimidine metabolism_Homo sapiens_hsa002401.66234439
21Insulin secretion_Homo sapiens_hsa049111.64316954
22Gastric acid secretion_Homo sapiens_hsa049711.64241395
23GABAergic synapse_Homo sapiens_hsa047271.62758729
24Nitrogen metabolism_Homo sapiens_hsa009101.62030148
25Vitamin B6 metabolism_Homo sapiens_hsa007501.60968874
26Dopaminergic synapse_Homo sapiens_hsa047281.58132165
27Oxytocin signaling pathway_Homo sapiens_hsa049211.57478814
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.55512392
29Cholinergic synapse_Homo sapiens_hsa047251.54487525
30Salivary secretion_Homo sapiens_hsa049701.53875541
31VEGF signaling pathway_Homo sapiens_hsa043701.53840569
32Glutamatergic synapse_Homo sapiens_hsa047241.40426015
33Gap junction_Homo sapiens_hsa045401.38436029
34Morphine addiction_Homo sapiens_hsa050321.38193501
35Glioma_Homo sapiens_hsa052141.34258748
36Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.33439130
37GnRH signaling pathway_Homo sapiens_hsa049121.30368244
38Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.28401222
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.26671557
40Cocaine addiction_Homo sapiens_hsa050301.22588406
41Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.21161737
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.19103750
43Nicotine addiction_Homo sapiens_hsa050331.18629494
44B cell receptor signaling pathway_Homo sapiens_hsa046621.17288763
45Estrogen signaling pathway_Homo sapiens_hsa049151.15528503
46Vibrio cholerae infection_Homo sapiens_hsa051101.15117828
47Central carbon metabolism in cancer_Homo sapiens_hsa052301.13169843
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12776210
49Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.12229849
50Cardiac muscle contraction_Homo sapiens_hsa042601.10253779
51cAMP signaling pathway_Homo sapiens_hsa040241.08456673
52Calcium signaling pathway_Homo sapiens_hsa040201.06375730
53Dilated cardiomyopathy_Homo sapiens_hsa054141.02405740
54Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.02245763
55Pancreatic cancer_Homo sapiens_hsa052120.99276568
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99260815
57Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.98404509
58mTOR signaling pathway_Homo sapiens_hsa041500.98257290
59Sulfur relay system_Homo sapiens_hsa041220.96962763
60Endocytosis_Homo sapiens_hsa041440.95894146
61Renin secretion_Homo sapiens_hsa049240.95529507
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95318808
63Apoptosis_Homo sapiens_hsa042100.94636013
64HTLV-I infection_Homo sapiens_hsa051660.94340676
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92255766
66Insulin signaling pathway_Homo sapiens_hsa049100.91820442
67Lysosome_Homo sapiens_hsa041420.91759739
68Non-small cell lung cancer_Homo sapiens_hsa052230.91481281
69Toll-like receptor signaling pathway_Homo sapiens_hsa046200.91013694
70Oocyte meiosis_Homo sapiens_hsa041140.89709649
71Shigellosis_Homo sapiens_hsa051310.87260543
72N-Glycan biosynthesis_Homo sapiens_hsa005100.87017675
73Vascular smooth muscle contraction_Homo sapiens_hsa042700.83992042
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83959121
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.83641093
76Platelet activation_Homo sapiens_hsa046110.83512107
77Biosynthesis of amino acids_Homo sapiens_hsa012300.83165282
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.83150436
79Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.82275567
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80598424
81Bladder cancer_Homo sapiens_hsa052190.79881439
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.79717434
83Rap1 signaling pathway_Homo sapiens_hsa040150.79714589
84ECM-receptor interaction_Homo sapiens_hsa045120.79448896
85Chronic myeloid leukemia_Homo sapiens_hsa052200.78480515
86Folate biosynthesis_Homo sapiens_hsa007900.75198212
87ErbB signaling pathway_Homo sapiens_hsa040120.74577019
88Glucagon signaling pathway_Homo sapiens_hsa049220.73356539
89Galactose metabolism_Homo sapiens_hsa000520.72999790
90HIF-1 signaling pathway_Homo sapiens_hsa040660.72365425
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.69903893
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69894659
93Melanogenesis_Homo sapiens_hsa049160.69620142
94Salmonella infection_Homo sapiens_hsa051320.69036366
95Thyroid cancer_Homo sapiens_hsa052160.67356521
96Prion diseases_Homo sapiens_hsa050200.66159236
97Pancreatic secretion_Homo sapiens_hsa049720.65935965
98Carbon metabolism_Homo sapiens_hsa012000.65284162
99Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.63823577
100Fructose and mannose metabolism_Homo sapiens_hsa000510.63788035
101Notch signaling pathway_Homo sapiens_hsa043300.62889101
102Osteoclast differentiation_Homo sapiens_hsa043800.62117295
103Endometrial cancer_Homo sapiens_hsa052130.61831856
104Type II diabetes mellitus_Homo sapiens_hsa049300.61791686
105AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61191524
106Thyroid hormone synthesis_Homo sapiens_hsa049180.60847361
107Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.60158996
108Colorectal cancer_Homo sapiens_hsa052100.59962613
109Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59929095
110Alzheimers disease_Homo sapiens_hsa050100.58577566
111Acute myeloid leukemia_Homo sapiens_hsa052210.58424897
112Cyanoamino acid metabolism_Homo sapiens_hsa004600.58066889
113Primary immunodeficiency_Homo sapiens_hsa053400.57945885
114Parkinsons disease_Homo sapiens_hsa050120.57586511
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57469534
116Taste transduction_Homo sapiens_hsa047420.57080921
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.56973159
118Amoebiasis_Homo sapiens_hsa051460.56314129
119Viral myocarditis_Homo sapiens_hsa054160.55801592
120Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55542179
121Alcoholism_Homo sapiens_hsa050340.55139460
122Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54963826
123Epstein-Barr virus infection_Homo sapiens_hsa051690.54126237
124Prolactin signaling pathway_Homo sapiens_hsa049170.54112705
125Leishmaniasis_Homo sapiens_hsa051400.54036027
126Long-term depression_Homo sapiens_hsa047300.53296108
127Bile secretion_Homo sapiens_hsa049760.52718190
128Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52286405
129Hepatitis B_Homo sapiens_hsa051610.51859607
130Focal adhesion_Homo sapiens_hsa045100.50912469
131Sphingolipid signaling pathway_Homo sapiens_hsa040710.50138677
132TNF signaling pathway_Homo sapiens_hsa046680.49539899
133Choline metabolism in cancer_Homo sapiens_hsa052310.49152557
134MAPK signaling pathway_Homo sapiens_hsa040100.49135549
135Small cell lung cancer_Homo sapiens_hsa052220.48410595
136Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.48390655
137Proteoglycans in cancer_Homo sapiens_hsa052050.47821632
138Huntingtons disease_Homo sapiens_hsa050160.47786539
139Melanoma_Homo sapiens_hsa052180.47740060
140Purine metabolism_Homo sapiens_hsa002300.47058705
141RNA polymerase_Homo sapiens_hsa030200.44254656
142Toxoplasmosis_Homo sapiens_hsa051450.44238061
143Oxidative phosphorylation_Homo sapiens_hsa001900.42751377
144Tuberculosis_Homo sapiens_hsa051520.42474707
145Viral carcinogenesis_Homo sapiens_hsa052030.39864436
146Glutathione metabolism_Homo sapiens_hsa004800.39464828
147Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.35710532
148PI3K-Akt signaling pathway_Homo sapiens_hsa041510.35085523

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »