CCDC85C

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1desmosome organization (GO:0002934)4.57080458
2layer formation in cerebral cortex (GO:0021819)4.50515081
3locomotory exploration behavior (GO:0035641)4.38771262
4synaptic vesicle maturation (GO:0016188)4.31008892
5sodium ion export (GO:0071436)4.00553004
6regulation of short-term neuronal synaptic plasticity (GO:0048172)3.98488653
7activation of Rac GTPase activity (GO:0032863)3.87262146
8cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.86316981
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.85059976
10vocalization behavior (GO:0071625)3.82839108
11cytoskeletal anchoring at plasma membrane (GO:0007016)3.80176553
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.65360304
13cell communication by electrical coupling (GO:0010644)3.64862959
14planar cell polarity pathway involved in neural tube closure (GO:0090179)3.63175608
15pre-miRNA processing (GO:0031054)3.60293713
16positive regulation of synapse maturation (GO:0090129)3.37222640
17dendritic spine morphogenesis (GO:0060997)3.36046516
18regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.35147798
19insulin-like growth factor receptor signaling pathway (GO:0048009)3.33654976
20neuromuscular process controlling balance (GO:0050885)3.30969143
21proline biosynthetic process (GO:0006561)3.30196307
22cell communication involved in cardiac conduction (GO:0086065)3.27968479
23regulation of synapse structural plasticity (GO:0051823)3.27764546
24negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.22691536
25negative regulation of potassium ion transmembrane transport (GO:1901380)3.18146940
26regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.17755019
27cellular potassium ion homeostasis (GO:0030007)3.15965039
28synaptic vesicle docking involved in exocytosis (GO:0016081)3.13327585
29bundle of His cell to Purkinje myocyte communication (GO:0086069)3.10717473
30glutamate secretion (GO:0014047)3.10355365
31regulation of mammary gland epithelial cell proliferation (GO:0033599)3.08269859
32establishment of nucleus localization (GO:0040023)3.07892955
33activation of protein kinase A activity (GO:0034199)3.07319048
34peptidyl-lysine dimethylation (GO:0018027)3.06991593
35gamma-aminobutyric acid transport (GO:0015812)3.06001877
36maternal placenta development (GO:0001893)3.05521807
37cell-substrate junction assembly (GO:0007044)3.05079379
38regulation of branching involved in prostate gland morphogenesis (GO:0060687)3.03571465
39negative regulation of fatty acid transport (GO:2000192)3.02803880
40neurotransmitter secretion (GO:0007269)3.01507039
41regulation of NFAT protein import into nucleus (GO:0051532)3.00536594
42plasma membrane repair (GO:0001778)2.99076146
43regulation of glutamate receptor signaling pathway (GO:1900449)2.97865613
44epithelial cell-cell adhesion (GO:0090136)2.97247750
45negative regulation of cell size (GO:0045792)2.95454781
46atrioventricular valve morphogenesis (GO:0003181)2.94906664
47embryonic eye morphogenesis (GO:0048048)2.94482821
48apoptotic process involved in morphogenesis (GO:0060561)2.94237376
49cell migration in hindbrain (GO:0021535)2.93946425
50dicarboxylic acid biosynthetic process (GO:0043650)2.91139236
51proline metabolic process (GO:0006560)2.87289500
52regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.86845013
53nuclear pore complex assembly (GO:0051292)2.86555585
54embryonic camera-type eye morphogenesis (GO:0048596)2.85974869
55exploration behavior (GO:0035640)2.84514139
56notochord development (GO:0030903)2.83692443
57cerebellar Purkinje cell layer development (GO:0021680)2.83291717
58mitotic chromosome condensation (GO:0007076)2.79629519
59regulation of glucose import in response to insulin stimulus (GO:2001273)2.77540470
60proline transport (GO:0015824)2.74244153
61regulation of histone H3-K27 methylation (GO:0061085)2.73981957
62negative regulation of organelle assembly (GO:1902116)2.73961337
63regulation of ARF protein signal transduction (GO:0032012)2.73758336
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.73412612
65regulation of cholesterol homeostasis (GO:2000188)2.73260285
66regulation of neuronal synaptic plasticity (GO:0048168)2.73103048
67regulation of clathrin-mediated endocytosis (GO:2000369)2.71607763
68regulation of water loss via skin (GO:0033561)2.70630167
69regulation of long-term neuronal synaptic plasticity (GO:0048169)2.70502716
70glucocorticoid receptor signaling pathway (GO:0042921)2.69985935
71hemidesmosome assembly (GO:0031581)2.69866370
72convergent extension (GO:0060026)2.66858705
73heterochromatin organization (GO:0070828)2.65222597
74membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.62051988
75neurotransmitter-gated ion channel clustering (GO:0072578)2.61363205
76Golgi transport vesicle coating (GO:0048200)2.61301346
77COPI coating of Golgi vesicle (GO:0048205)2.61301346
78regulation of dendritic spine morphogenesis (GO:0061001)2.61030292
79adherens junction assembly (GO:0034333)2.60676392
80apical protein localization (GO:0045176)2.60277301
81hippo signaling (GO:0035329)2.60062994
82embryonic retina morphogenesis in camera-type eye (GO:0060059)2.59789020
83RNA stabilization (GO:0043489)2.59642793
84mRNA stabilization (GO:0048255)2.59642793
85glycine transport (GO:0015816)2.58376631
86retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.57403145
87auditory behavior (GO:0031223)2.57274216
88regulation of ARF GTPase activity (GO:0032312)2.57172064
89establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.56993134
90regulation of hippo signaling (GO:0035330)2.56959811
91paraxial mesoderm development (GO:0048339)2.56334921
92synaptic vesicle exocytosis (GO:0016079)2.56157594
93regulation of translational termination (GO:0006449)2.55527211
94positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.55237808
95regulation of cardioblast differentiation (GO:0051890)2.55049557
96prepulse inhibition (GO:0060134)2.53714812
97regulation of translational fidelity (GO:0006450)2.52688153
98regulation of synaptic vesicle exocytosis (GO:2000300)2.52635695
99gap junction assembly (GO:0016264)2.52127948
100regulation of RNA export from nucleus (GO:0046831)2.51359178
101establishment of apical/basal cell polarity (GO:0035089)2.50918127
102branching involved in mammary gland duct morphogenesis (GO:0060444)2.50806449
103cerebellar Purkinje cell differentiation (GO:0021702)2.49676562
104urea cycle (GO:0000050)2.49377882
105cell junction maintenance (GO:0034331)2.49223390
106potassium ion import (GO:0010107)2.48754887
107DNA unwinding involved in DNA replication (GO:0006268)2.48537821
108establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.48292947
109mitochondrion transport along microtubule (GO:0047497)2.48292947
110semaphorin-plexin signaling pathway (GO:0071526)2.48049650
111cellular protein complex localization (GO:0034629)2.47441914
112cellular response to epidermal growth factor stimulus (GO:0071364)2.47343320
113spliceosomal tri-snRNP complex assembly (GO:0000244)2.45898211
114protein complex localization (GO:0031503)2.44626788
115alanine transport (GO:0032328)2.43926383
116cellular sodium ion homeostasis (GO:0006883)2.43555571
117endothelial cell chemotaxis (GO:0035767)2.42976878
118epithelial cell differentiation involved in prostate gland development (GO:0060742)2.42067575
119cardiac myofibril assembly (GO:0055003)2.41859116
120positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.41002575
121asymmetric protein localization (GO:0008105)2.40474330
122dendrite morphogenesis (GO:0048813)2.39758992
123cerebellar granule cell differentiation (GO:0021707)2.39612202
124embryonic process involved in female pregnancy (GO:0060136)2.38855779
125Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.38705976
126histone H3-K36 demethylation (GO:0070544)2.38457938
127regulation of nucleobase-containing compound transport (GO:0032239)2.38358099
128regulation of fatty acid beta-oxidation (GO:0031998)2.37982403
129positive regulation of keratinocyte differentiation (GO:0045618)2.37507738
130protein localization to synapse (GO:0035418)2.37428403
131protein retention in ER lumen (GO:0006621)2.37375955
132lung epithelium development (GO:0060428)2.37156569
133nuclear pore organization (GO:0006999)2.37037608
134nucleosome disassembly (GO:0006337)2.36977690
135protein-DNA complex disassembly (GO:0032986)2.36977690
136protein localization to microtubule (GO:0035372)2.36925331
137regulation of cholesterol biosynthetic process (GO:0045540)2.36062672
138negative regulation of cytosolic calcium ion concentration (GO:0051481)2.35430895
139positive regulation of fatty acid beta-oxidation (GO:0032000)2.35343132
140establishment or maintenance of apical/basal cell polarity (GO:0035088)2.35182028
141establishment or maintenance of bipolar cell polarity (GO:0061245)2.35182028
142focal adhesion assembly (GO:0048041)2.35179829
143cell-substrate adherens junction assembly (GO:0007045)2.35179829
144adherens junction organization (GO:0034332)2.35112304
145polarized epithelial cell differentiation (GO:0030859)2.34762777
146biotin metabolic process (GO:0006768)2.34314244
147urea metabolic process (GO:0019627)2.34121038
148cardiac muscle contraction (GO:0060048)2.33890156
149trophectodermal cell differentiation (GO:0001829)2.32874495
150ventricular cardiac muscle cell action potential (GO:0086005)2.32495281
151potassium ion homeostasis (GO:0055075)2.31738713
152mitotic G1 DNA damage checkpoint (GO:0031571)2.31417078
153establishment of monopolar cell polarity (GO:0061162)2.31300739
154establishment or maintenance of monopolar cell polarity (GO:0061339)2.31300739
155maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.30404184
156cell-cell junction maintenance (GO:0045217)2.30110935
157neuromuscular process controlling posture (GO:0050884)2.29895065
158G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.29742997
159regulation of membrane repolarization (GO:0060306)2.29327336
160neural tube development (GO:0021915)2.28597137
161CDP-diacylglycerol biosynthetic process (GO:0016024)2.28126922
162glial cell proliferation (GO:0014009)2.27351873
163membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.27314839
164regulation of establishment of planar polarity (GO:0090175)2.27057293
165myelin maintenance (GO:0043217)2.26224973
166neuromuscular process (GO:0050905)2.26130496
167dendritic spine organization (GO:0097061)2.25576821
168lysine catabolic process (GO:0006554)2.25491391
169lysine metabolic process (GO:0006553)2.25491391
170corticosteroid receptor signaling pathway (GO:0031958)2.25376506
171signal complex assembly (GO:0007172)2.25044293
172glutamine family amino acid biosynthetic process (GO:0009084)2.24368028
173mammary gland epithelial cell differentiation (GO:0060644)2.24085122
174regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.23782846
175aspartate family amino acid catabolic process (GO:0009068)2.23776322
176negative regulation of catenin import into nucleus (GO:0035414)2.23757957
177carnitine shuttle (GO:0006853)2.23303599
178positive regulation of dendritic spine morphogenesis (GO:0061003)2.22068697
179eye morphogenesis (GO:0048592)2.20976218

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human3.52873989
2* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.46239141
3SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.50430670
4ZFP281_18757296_ChIP-ChIP_E14_Mouse2.50423316
5MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.47983218
6ZNF263_19887448_ChIP-Seq_K562_Human2.44322088
7RARB_27405468_Chip-Seq_BRAIN_Mouse2.42910345
8EZH2_22144423_ChIP-Seq_EOC_Human2.30963946
9* KDM2B_26808549_Chip-Seq_K562_Human2.22750574
10ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.20434416
11* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.15713911
12DROSHA_22980978_ChIP-Seq_HELA_Human2.12217491
13KDM2B_26808549_Chip-Seq_SUP-B15_Human2.11362234
14ESR1_21235772_ChIP-Seq_MCF-7_Human2.06265677
15* KDM2B_26808549_Chip-Seq_DND41_Human2.05139835
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.01631773
17RARG_19884340_ChIP-ChIP_MEFs_Mouse1.98779422
18ERG_21242973_ChIP-ChIP_JURKAT_Human1.98040158
19LXR_22292898_ChIP-Seq_THP-1_Human1.95216494
20STAT6_21828071_ChIP-Seq_BEAS2B_Human1.91092247
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.88456755
22AR_21909140_ChIP-Seq_LNCAP_Human1.86735491
23EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.84836863
24TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.74830451
25VDR_21846776_ChIP-Seq_THP-1_Human1.73027861
26WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.70877697
27TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.66655689
28ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.65616745
29KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.65488160
30DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.63290983
31* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.62800375
32CLOCK_20551151_ChIP-Seq_293T_Human1.62257873
33KDM2B_26808549_Chip-Seq_JURKAT_Human1.61377493
34E2F7_22180533_ChIP-Seq_HELA_Human1.60771352
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.59148368
36SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.59003999
37ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.58747079
38SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.57824461
39DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.57677185
40* CREB1_26743006_Chip-Seq_LNCaP_Human1.56187948
41DNAJC2_21179169_ChIP-ChIP_NT2_Human1.54712073
42REST_21632747_ChIP-Seq_MESCs_Mouse1.54336493
43PKCTHETA_26484144_Chip-Seq_BREAST_Human1.53213329
44HIF1A_21447827_ChIP-Seq_MCF-7_Human1.50509020
45TCF7_22412390_ChIP-Seq_EML_Mouse1.50251444
46MYC_22102868_ChIP-Seq_BL_Human1.49523061
47GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.48446926
48TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.48311778
49RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.47046688
50ESR1_15608294_ChIP-ChIP_MCF-7_Human1.46225942
51NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.44508366
52REST_18959480_ChIP-ChIP_MESCs_Mouse1.44231274
53ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.43132327
54ESR2_21235772_ChIP-Seq_MCF-7_Human1.43016965
55CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.42766668
56* CHD1_26751641_Chip-Seq_LNCaP_Human1.41938245
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.41869987
58* RACK7_27058665_Chip-Seq_MCF-7_Human1.40706170
59ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.40158160
60CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.38250019
61* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35452436
62RNF2_18974828_ChIP-Seq_MESCs_Mouse1.35419357
63EZH2_18974828_ChIP-Seq_MESCs_Mouse1.35419357
64EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.35343682
65RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34271437
66NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.33859680
67* CTCF_27219007_Chip-Seq_Bcells_Human1.30389523
68* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.30016103
69TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29358324
70* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28069416
71SOX9_24532713_ChIP-Seq_HFSC_Mouse1.27162136
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.26171514
73* PPARA_22158963_ChIP-Seq_LIVER_Mouse1.25767395
74* GATA6_25053715_ChIP-Seq_YYC3_Human1.25525719
75MTF2_20144788_ChIP-Seq_MESCs_Mouse1.23648945
76RXR_22158963_ChIP-Seq_LIVER_Mouse1.23287921
77SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.23060142
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.22740838
79RUNX1_27514584_Chip-Seq_MCF-7_Human1.21699982
80* EZH2_27294783_Chip-Seq_ESCs_Mouse1.21628595
81KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.21206797
82RNF2_27304074_Chip-Seq_ESCs_Mouse1.21116968
83P68_20966046_ChIP-Seq_HELA_Human1.19265866
84ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.18916014
85NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.18537897
86* SMC4_20622854_ChIP-Seq_HELA_Human1.18286156
87* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.18002038
88WT1_25993318_ChIP-Seq_PODOCYTE_Human1.17958684
89SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.17684973
90* UBF1/2_26484160_Chip-Seq_HMECs_Human1.17640647
91POU5F1_16518401_ChIP-PET_MESCs_Mouse1.16618317
92ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.16586084
93LXR_22158963_ChIP-Seq_LIVER_Mouse1.16382027
94RING1B_27294783_Chip-Seq_NPCs_Mouse1.16319669
95NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.15799491
96KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15717367
97THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.15582036
98TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.15227836
99CTCF_27219007_Chip-Seq_ERYTHROID_Human1.15026061
100MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.13934851
101SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.13913268
102JARID2_20075857_ChIP-Seq_MESCs_Mouse1.13235094
103SA1_27219007_Chip-Seq_ERYTHROID_Human1.12489478
104* RING1B_27294783_Chip-Seq_ESCs_Mouse1.12398647
105* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.12261722
106CDX2_20551321_ChIP-Seq_CACO-2_Human1.11701871
107NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10542694
108JARID2_20064375_ChIP-Seq_MESCs_Mouse1.08642187
109RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08203357
110* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07668801
111TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07603016
112FOXA2_19822575_ChIP-Seq_HepG2_Human1.07143555
113PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06923738
114ELK3_25401928_ChIP-Seq_HUVEC_Human1.06094123
115CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.05591436
116ESR1_20079471_ChIP-ChIP_T-47D_Human1.05070164
117SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.04498199
118* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.04140467
119SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.03695774
120TET1_21490601_ChIP-Seq_MESCs_Mouse1.03560433
121ZFX_18555785_ChIP-Seq_MESCs_Mouse1.01926281
122NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.00898822
123TBX20_22328084_ChIP-Seq_HEART_Mouse1.00865171
124TBX20_22080862_ChIP-Seq_HEART_Mouse1.00865171
125CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00208736
126UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00005879
127PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.98281853
128* ISL1_27105846_Chip-Seq_CPCs_Mouse0.98178229
129AR_19668381_ChIP-Seq_PC3_Human0.98009351
130CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97963237
131SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.97942972
132SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.97942972
133* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.97702410
134OCT4_19829295_ChIP-Seq_ESCs_Human0.96976047
135MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.96557464
136SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95895033
137KLF4_19829295_ChIP-Seq_ESCs_Human0.95782014
138* FOXM1_23109430_ChIP-Seq_U2OS_Human0.95281536
139FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.95239292
140* ATF3_27146783_Chip-Seq_COLON_Human0.95073259
141TP53_22127205_ChIP-Seq_IMR90_Human0.94804717
142FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.94094386
143* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.93014846

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.70960668
2MP0003705_abnormal_hypodermis_morpholog3.39164429
3MP0002822_catalepsy3.05803177
4MP0000566_synostosis2.83447464
5MP0005409_darkened_coat_color2.77040740
6MP0003635_abnormal_synaptic_transmissio2.56251273
7MP0004858_abnormal_nervous_system2.39357918
8MP0004270_analgesia2.38519252
9MP0010234_abnormal_vibrissa_follicle2.37337643
10MP0002796_impaired_skin_barrier2.37080834
11MP0003283_abnormal_digestive_organ2.29363668
12MP0004233_abnormal_muscle_weight2.18514542
13MP0000579_abnormal_nail_morphology2.17051333
14MP0005360_urolithiasis2.16705809
15MP0002653_abnormal_ependyma_morphology2.15155137
16MP0000751_myopathy2.12611278
17MP0003646_muscle_fatigue2.07846456
18MP0002249_abnormal_larynx_morphology2.06371851
19MP0002063_abnormal_learning/memory/cond2.04129853
20MP0008961_abnormal_basal_metabolism2.02883430
21MP0005451_abnormal_body_composition1.86763440
22MP0003123_paternal_imprinting1.84919029
23MP0009046_muscle_twitch1.82814642
24MP0001346_abnormal_lacrimal_gland1.79711240
25MP0010030_abnormal_orbit_morphology1.76566930
26MP0009745_abnormal_behavioral_response1.75132650
27MP0002098_abnormal_vibrissa_morphology1.74773059
28MP0002837_dystrophic_cardiac_calcinosis1.72436704
29MP0002909_abnormal_adrenal_gland1.71210050
30MP0005501_abnormal_skin_physiology1.69771019
31MP0000537_abnormal_urethra_morphology1.66959389
32MP0003453_abnormal_keratinocyte_physiol1.65272197
33MP0001849_ear_inflammation1.63911257
34MP0009780_abnormal_chondrocyte_physiolo1.63729179
35MP0003329_amyloid_beta_deposits1.60533242
36MP0003566_abnormal_cell_adhesion1.59682354
37MP0004084_abnormal_cardiac_muscle1.58038545
38MP0002269_muscular_atrophy1.57054033
39MP0005085_abnormal_gallbladder_physiolo1.56882015
40MP0003137_abnormal_impulse_conducting1.56280840
41MP0002064_seizures1.55508083
42MP0004130_abnormal_muscle_cell1.55136587
43MP0010678_abnormal_skin_adnexa1.54416700
44MP0005187_abnormal_penis_morphology1.53980575
45MP0005076_abnormal_cell_differentiation1.53660742
46MP0009672_abnormal_birth_weight1.52608607
47MP0002139_abnormal_hepatobiliary_system1.51894646
48MP0004087_abnormal_muscle_fiber1.51470925
49MP0002009_preneoplasia1.48538914
50MP0005623_abnormal_meninges_morphology1.42126334
51MP0004811_abnormal_neuron_physiology1.41802335
52MP0005423_abnormal_somatic_nervous1.41580528
53MP0000383_abnormal_hair_follicle1.36656782
54MP0004885_abnormal_endolymph1.36358340
55MP0004145_abnormal_muscle_electrophysio1.35845092
56MP0008569_lethality_at_weaning1.35470596
57MP0002877_abnormal_melanocyte_morpholog1.33425826
58MP0004215_abnormal_myocardial_fiber1.32481346
59MP0002572_abnormal_emotion/affect_behav1.32114097
60MP0010352_gastrointestinal_tract_polyps1.31125663
61MP0003119_abnormal_digestive_system1.26747337
62MP0008057_abnormal_DNA_replication1.26491672
63MP0000955_abnormal_spinal_cord1.25622229
64MP0000762_abnormal_tongue_morphology1.24257135
65MP0005330_cardiomyopathy1.23575979
66MP0002697_abnormal_eye_size1.23444258
67MP0009053_abnormal_anal_canal1.22426451
68MP0004036_abnormal_muscle_relaxation1.21629918
69MP0003315_abnormal_perineum_morphology1.20212547
70MP0003111_abnormal_nucleus_morphology1.20111834
71MP0001348_abnormal_lacrimal_gland1.20022720
72MP0000733_abnormal_muscle_development1.19111259
73MP0001486_abnormal_startle_reflex1.17870679
74MP0003942_abnormal_urinary_system1.16625815
75MP0003984_embryonic_growth_retardation1.15520778
76MP0004085_abnormal_heartbeat1.15134794
77MP0010630_abnormal_cardiac_muscle1.15129534
78MP0000377_abnormal_hair_follicle1.14999262
79MP0000747_muscle_weakness1.14916654
80MP0003115_abnormal_respiratory_system1.13349488
81MP0000462_abnormal_digestive_system1.12214391
82MP0002088_abnormal_embryonic_growth/wei1.10907590
83MP0000778_abnormal_nervous_system1.09360016
84MP0004782_abnormal_surfactant_physiolog1.08874498
85MP0000467_abnormal_esophagus_morphology1.08629104
86MP0002152_abnormal_brain_morphology1.07456169
87MP0003693_abnormal_embryo_hatching1.06606693
88MP0005167_abnormal_blood-brain_barrier1.06229765
89MP0000678_abnormal_parathyroid_gland1.05967837
90MP0001216_abnormal_epidermal_layer1.04901669
91MP0002734_abnormal_mechanical_nocicepti1.03738043
92MP0010329_abnormal_lipoprotein_level1.03447828
93MP0005386_behavior/neurological_phenoty1.02961685
94MP0004924_abnormal_behavior1.02961685
95MP0009840_abnormal_foam_cell1.02238248
96MP0004185_abnormal_adipocyte_glucose1.01219528
97MP0006138_congestive_heart_failure1.00894307
98MP0005365_abnormal_bile_salt0.99839906
99MP0002272_abnormal_nervous_system0.99358019
100MP0003861_abnormal_nervous_system0.97084382
101MP0003252_abnormal_bile_duct0.96971980
102MP0002085_abnormal_embryonic_tissue0.96719809
103MP0002089_abnormal_postnatal_growth/wei0.95786255
104MP0002084_abnormal_developmental_patter0.95402335
105MP0001440_abnormal_grooming_behavior0.95130002
106MP0003633_abnormal_nervous_system0.92182955
107MP0002184_abnormal_innervation0.92009098
108MP0002080_prenatal_lethality0.91023902
109MP0002066_abnormal_motor_capabilities/c0.90129740
110MP0002733_abnormal_thermal_nociception0.90088913
111MP0002234_abnormal_pharynx_morphology0.89742470
112MP0003941_abnormal_skin_development0.89709076
113MP0003890_abnormal_embryonic-extraembry0.89404652
114MP0004264_abnormal_extraembryonic_tissu0.89294421
115MP0005666_abnormal_adipose_tissue0.89209320
116MP0002882_abnormal_neuron_morphology0.87352664
117MP0000759_abnormal_skeletal_muscle0.87347453
118MP0002092_abnormal_eye_morphology0.86303820
119MP0000350_abnormal_cell_proliferation0.85921972
120MP0001697_abnormal_embryo_size0.85889738
121MP0005620_abnormal_muscle_contractility0.85784252
122MP0003077_abnormal_cell_cycle0.85221589
123MP0002557_abnormal_social/conspecific_i0.85179608
124MP0010771_integument_phenotype0.84941888
125MP0001730_embryonic_growth_arrest0.84513292
126MP0009703_decreased_birth_body0.84339359
127MP0000003_abnormal_adipose_tissue0.83849046
128MP0001340_abnormal_eyelid_morphology0.83591631
129MP0000428_abnormal_craniofacial_morphol0.83412207
130MP0000534_abnormal_ureter_morphology0.83085674
131MP0003091_abnormal_cell_migration0.82550570
132MP0003632_abnormal_nervous_system0.81839209
133MP0003935_abnormal_craniofacial_develop0.81168376
134MP0004197_abnormal_fetal_growth/weight/0.80880819
135MP0002106_abnormal_muscle_physiology0.80427343
136MP0003075_altered_response_to0.80341622
137MP0002060_abnormal_skin_morphology0.80017886
138MP0005375_adipose_tissue_phenotype0.79967635
139MP0003631_nervous_system_phenotype0.79807940
140MP0008874_decreased_physiological_sensi0.79760302
141MP0004957_abnormal_blastocyst_morpholog0.78555444
142MP0002111_abnormal_tail_morphology0.78511329
143MP0000627_abnormal_mammary_gland0.77696169
144MP0008770_decreased_survivor_rate0.77672760
145MP0005248_abnormal_Harderian_gland0.77145692
146MP0001666_abnormal_nutrient_absorption0.77067492
147MP0003879_abnormal_hair_cell0.76616599
148MP0002116_abnormal_craniofacial_bone0.76420074
149MP0003880_abnormal_central_pattern0.74636509
150MP0002086_abnormal_extraembryonic_tissu0.74341091
151MP0001544_abnormal_cardiovascular_syste0.73679373
152MP0005385_cardiovascular_system_phenoty0.73679373
153MP0003385_abnormal_body_wall0.73585446
154MP0001672_abnormal_embryogenesis/_devel0.73511222
155MP0005380_embryogenesis_phenotype0.73511222
156MP0000432_abnormal_head_morphology0.73462631
157MP0003937_abnormal_limbs/digits/tail_de0.73382752
158MP0005670_abnormal_white_adipose0.73371621
159MP0002972_abnormal_cardiac_muscle0.73328009
160MP0001188_hyperpigmentation0.73219262
161MP0009931_abnormal_skin_appearance0.71402797

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)4.71383346
2Myokymia (HP:0002411)3.65899358
3Dysmetric saccades (HP:0000641)3.61847941
4Broad face (HP:0000283)3.31939967
5Asymmetry of the thorax (HP:0001555)3.18769272
6Hyperacusis (HP:0010780)3.17641738
7Ulnar bowing (HP:0003031)3.11620141
8Bundle branch block (HP:0011710)2.99306824
9Annular pancreas (HP:0001734)2.95290226
10Insomnia (HP:0100785)2.94870877
11Bronchomalacia (HP:0002780)2.94531583
12Visual hallucinations (HP:0002367)2.90647651
13Abnormality of the distal phalanx of the thumb (HP:0009617)2.88888454
14Sudden death (HP:0001699)2.87051591
15Obstructive sleep apnea (HP:0002870)2.84206419
16Flat acetabular roof (HP:0003180)2.76656901
17Ventricular fibrillation (HP:0001663)2.76004343
18Difficulty running (HP:0009046)2.75941173
19Resting tremor (HP:0002322)2.74840122
20Upper limb amyotrophy (HP:0009129)2.71490199
21Distal upper limb amyotrophy (HP:0007149)2.71490199
22Action tremor (HP:0002345)2.62189079
23Exercise-induced muscle cramps (HP:0003710)2.62180817
24Exercise-induced myalgia (HP:0003738)2.62028829
25Germ cell neoplasia (HP:0100728)2.60917304
26Elfin facies (HP:0004428)2.60803573
27Astrocytoma (HP:0009592)2.56181178
28Abnormality of the astrocytes (HP:0100707)2.56181178
29Pointed chin (HP:0000307)2.55001518
30Hemiplegia (HP:0002301)2.54777093
31Achilles tendon contracture (HP:0001771)2.53499278
32Hand muscle atrophy (HP:0009130)2.53003499
33Abnormality of the Achilles tendon (HP:0005109)2.49945265
34Focal seizures (HP:0007359)2.46524633
35Hyporeflexia of lower limbs (HP:0002600)2.40134717
36Sparse lateral eyebrow (HP:0005338)2.39626732
37Renovascular hypertension (HP:0100817)2.36585326
38Dysdiadochokinesis (HP:0002075)2.34202565
39Abnormal social behavior (HP:0012433)2.31238515
40Impaired social interactions (HP:0000735)2.31238515
41Impaired vibration sensation in the lower limbs (HP:0002166)2.30839413
42Amyotrophic lateral sclerosis (HP:0007354)2.28830258
43Septate vagina (HP:0001153)2.28001154
44Ependymoma (HP:0002888)2.27687268
45Advanced eruption of teeth (HP:0006288)2.27188747
46Postural instability (HP:0002172)2.25600249
47Ankyloglossia (HP:0010296)2.25495162
48Urinary bladder sphincter dysfunction (HP:0002839)2.25355597
49Pseudobulbar signs (HP:0002200)2.23497028
50Insidious onset (HP:0003587)2.22902880
51Termporal pattern (HP:0011008)2.22902880
52Renal duplication (HP:0000075)2.22445659
53Urinary urgency (HP:0000012)2.21838523
54Abnormality of the fingertips (HP:0001211)2.21827249
55Cerebral aneurysm (HP:0004944)2.19583303
56Turricephaly (HP:0000262)2.17527884
57Long palpebral fissure (HP:0000637)2.16885619
58Thin bony cortex (HP:0002753)2.14778444
59Overriding aorta (HP:0002623)2.13120826
60Distal lower limb amyotrophy (HP:0008944)2.13111047
61Depression (HP:0000716)2.09372270
62Lip pit (HP:0100267)2.08693182
63Poor eye contact (HP:0000817)2.08372206
64Aplasia involving bones of the upper limbs (HP:0009823)2.04074274
65Aplasia of the phalanges of the hand (HP:0009802)2.04074274
66Aplasia involving bones of the extremities (HP:0009825)2.04074274
67Lymphangioma (HP:0100764)2.03672746
68Genetic anticipation (HP:0003743)2.02810762
69Impaired smooth pursuit (HP:0007772)2.02139913
70Macroorchidism (HP:0000053)2.01409290
71Ankle clonus (HP:0011448)2.00288277
72Right ventricular cardiomyopathy (HP:0011663)2.00181908
73Abnormality of the salivary glands (HP:0010286)1.99801588
74Heart block (HP:0012722)1.97622465
75EMG: neuropathic changes (HP:0003445)1.97394581
76Focal motor seizures (HP:0011153)1.97000775
77Myoglobinuria (HP:0002913)1.96064854
78Intention tremor (HP:0002080)1.95163440
79Difficulty climbing stairs (HP:0003551)1.94555129
80Cerebral inclusion bodies (HP:0100314)1.94233519
81Broad distal phalanx of finger (HP:0009836)1.93576395
82Intellectual disability, profound (HP:0002187)1.93268569
83Lower limb amyotrophy (HP:0007210)1.92139122
84Atrioventricular block (HP:0001678)1.91726174
85Abnormal ossification of hand bones (HP:0005921)1.90863884
86High anterior hairline (HP:0009890)1.89944086
87Syncope (HP:0001279)1.89846337
88Shallow orbits (HP:0000586)1.89448129
89Fibroma (HP:0010614)1.88866456
90Dislocated radial head (HP:0003083)1.87504629
91Hamartoma of the eye (HP:0010568)1.86947171
92Deviation of the thumb (HP:0009603)1.86921098
93Neoplasm of the heart (HP:0100544)1.86837478
94Status epilepticus (HP:0002133)1.86273296
95Anal stenosis (HP:0002025)1.85319258
96Urethral obstruction (HP:0000796)1.84904378
97Ventricular arrhythmia (HP:0004308)1.84815973
98Abnormality of the radial head (HP:0003995)1.84622826
99Short nail (HP:0001799)1.84230310
100Increased connective tissue (HP:0009025)1.84189952
101Disproportionate tall stature (HP:0001519)1.83833748
102Abnormal atrioventricular conduction (HP:0005150)1.83540034
103Neonatal hypoglycemia (HP:0001998)1.83142359
104Heterotopia (HP:0002282)1.82523773
105Abnormality of ocular smooth pursuit (HP:0000617)1.82229581
106Partial duplication of thumb phalanx (HP:0009944)1.81593618
107Supranuclear gaze palsy (HP:0000605)1.80802688
108Vertebral arch anomaly (HP:0008438)1.80636206
109Precocious puberty (HP:0000826)1.79899232
110Arnold-Chiari malformation (HP:0002308)1.79499323
111Abnormality of oral frenula (HP:0000190)1.79073134
112Fibrous tissue neoplasm (HP:0012316)1.79000928
113Prolonged QT interval (HP:0001657)1.78163707
114Hypopigmentation of the fundus (HP:0007894)1.77757740
115Amblyopia (HP:0000646)1.77100330
116Rapidly progressive (HP:0003678)1.75141573
117Deep venous thrombosis (HP:0002625)1.75101314
118Abnormality of the phalanges of the hallux (HP:0010057)1.72621304
119Abnormality of carpal bone ossification (HP:0006257)1.72449691
120Progressive cerebellar ataxia (HP:0002073)1.71941496
121Spinal cord compression (HP:0002176)1.71057378
122Ventricular tachycardia (HP:0004756)1.70387530
123Abnormality of the aortic arch (HP:0012303)1.70001925
124Coronal craniosynostosis (HP:0004440)1.69966410
125Abnormality of the gastric mucosa (HP:0004295)1.69828580
126Abnormality of the corticospinal tract (HP:0002492)1.69758849
127Patellar dislocation (HP:0002999)1.69437005
128Abnormality of the diencephalon (HP:0010662)1.68757512
129Pterygium (HP:0001059)1.68750421
130Tetraplegia (HP:0002445)1.68519119
131Abnormality of nail color (HP:0100643)1.67880943
132Long eyelashes (HP:0000527)1.67405023
133Dysmetria (HP:0001310)1.66398922
134Obsessive-compulsive behavior (HP:0000722)1.65938592
135Trigonocephaly (HP:0000243)1.65206944
136Duplication of thumb phalanx (HP:0009942)1.63959477
137Proximal placement of thumb (HP:0009623)1.63934279
138Atrial fibrillation (HP:0005110)1.63877053
139Glioma (HP:0009733)1.62888464
140Bowing of the arm (HP:0006488)1.62835989
141Bowed forearm bones (HP:0003956)1.62835989
142Angiofibromas (HP:0010615)1.62798974
143Adenoma sebaceum (HP:0009720)1.62798974
144Polygenic inheritance (HP:0010982)1.62494821
145Myotonia (HP:0002486)1.62146914
146Spastic diplegia (HP:0001264)1.62135770
147Midface retrusion (HP:0011800)1.61857123
148Primary atrial arrhythmia (HP:0001692)1.61464163
149Hemiparesis (HP:0001269)1.61299538
150Hepatoblastoma (HP:0002884)1.60739437
151Morphological abnormality of the pyramidal tract (HP:0002062)1.60618123
152Breast hypoplasia (HP:0003187)1.59015084
153Spastic gait (HP:0002064)1.58969023
154Increased nuchal translucency (HP:0010880)1.58774896
155Bowel incontinence (HP:0002607)1.56658181
156Spina bifida occulta (HP:0003298)1.56138210
157Thin ribs (HP:0000883)1.55571272
158Tracheomalacia (HP:0002779)1.53435048
159Selective tooth agenesis (HP:0001592)1.53320634
160Absent radius (HP:0003974)1.52199737
161Spinal cord lesions (HP:0100561)1.51427182
162Syringomyelia (HP:0003396)1.51427182
163Hemorrhage of the eye (HP:0011885)1.51062352
164Laryngomalacia (HP:0001601)1.50785867
165Skin pits (HP:0100276)1.50614247
166Abnormality of the nasal septum (HP:0000419)1.50126669
167Choanal stenosis (HP:0000452)1.49042581
168Abnormality of the humeroradial joint (HP:0100744)1.48013600
169Mitral regurgitation (HP:0001653)1.47954543
170Stridor (HP:0010307)1.47242929
171Hyperparathyroidism (HP:0000843)1.46617079
172Partial duplication of the phalanx of hand (HP:0009999)1.46517206
173Deep palmar crease (HP:0006191)1.46032643
174Abnormal tarsal ossification (HP:0008369)1.45933341
175Smooth philtrum (HP:0000319)1.45489498

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.25012942
2SMG13.00523903
3MAP3K92.99175059
4PKN22.94014604
5ICK2.76109953
6PRKD32.75844469
7EEF2K2.61084645
8RIPK12.57835351
9TYRO32.25110881
10MAP3K102.06796254
11EPHA42.00746668
12PAK61.97221479
13AKT31.87303398
14LATS21.87264790
15MARK11.83326350
16NEK11.82310500
17KSR21.81706221
18MST1R1.77464414
19CAMKK11.75127286
20CDK121.69218601
21MAP3K41.63719132
22NTRK21.62523731
23IRAK31.61858814
24FGFR41.61460824
25PHKG21.60673443
26PHKG11.60673443
27NTRK31.59364424
28ALK1.59114182
29NTRK11.58170299
30PDGFRA1.57501903
31TAOK11.57015221
32LMTK21.56725254
33DAPK21.53154027
34SCYL21.50800874
35STK381.49782830
36TTN1.48045264
37PRPF4B1.41407188
38PTK61.30667797
39BMX1.29828916
40PDK31.28094081
41PDK41.28094081
42MINK11.26030896
43DMPK1.20956372
44MET1.18095821
45KSR11.17287895
46BRD41.15081082
47DDR21.12695444
48MAP2K41.06464683
49MAP3K71.06221650
50RET1.02148331
51SIK21.01866937
52MTOR0.96608259
53SIK10.94774606
54STK110.94428963
55CDK80.93027271
56MAP2K20.92049356
57ERN10.90195449
58PINK10.90052277
59IRAK20.88814425
60CAMK1G0.88732057
61LATS10.88282325
62CDK50.79261980
63MAPK110.78744322
64CDK70.78293371
65MAP3K20.78250473
66MAPKAPK30.77478243
67MELK0.76594597
68UHMK10.72158980
69MARK20.72153284
70PAK30.71600436
71PRKAA10.70079633
72PRKCH0.70044147
73NEK60.69870819
74CAMK1D0.69045400
75DAPK10.68899734
76CAMK40.66768590
77SGK30.66115597
78CDC42BPA0.66064634
79PAK40.65691709
80PTK20.62244411
81PRKD20.58632849
82PDK10.57462353
83RPS6KA30.56884700
84CDK150.55913890
85PDGFRB0.55404261
86SGK2230.54337741
87SGK4940.54337741
88CDK60.53881310
89MAP3K60.53152522
90FGFR30.53011780
91PDK20.52982178
92NEK20.52677974
93PAK20.52596748
94HIPK20.51727713
95DYRK1B0.51439556
96WNK10.51144647
97FGFR20.49313192
98BRSK10.49175110
99CDK180.48465032
100ERBB20.48021799
101CDK11A0.47168078
102CDK40.47159480
103FGFR10.47059945
104PDPK10.46900767
105CSNK1D0.46898217
106AKT20.46714476
107RPS6KA10.46348302
108RPS6KL10.44862154
109RPS6KC10.44862154
110RPS6KB10.44156955
111CSNK1E0.43646545
112PRKD10.43416216
113ILK0.43092844
114EPHA20.41958598
115SGK10.41809419
116MAPK100.41329645
117MAP3K130.40452478
118SGK20.40209462
119BRAF0.40151493
120CDK90.39025976
121DAPK30.38688851
122PRKCZ0.38079503
123CHEK10.37955619
124MAP3K10.37771861
125RPS6KA20.37587965
126RPS6KB20.37308505
127CDK140.37227005
128EPHB20.37026918
129CDK10.36865444
130MAP2K10.36679229
131PRKCG0.36485835
132FER0.36051205
133CAMK10.34672706
134MAPK80.34650148
135MAP3K80.34606624
136ROCK10.34349296
137GRK60.34275010
138MAP2K30.33464071
139CAMK2B0.32181190
140GSK3B0.32172117
141CDK20.32168814
142PIK3CA0.31601009
143CHEK20.31328785

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.53903603
2Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.63644872
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.02656473
4Arginine biosynthesis_Homo sapiens_hsa002202.01845882
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.92937710
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.83233135
7Thyroid cancer_Homo sapiens_hsa052161.64600076
8Long-term potentiation_Homo sapiens_hsa047201.62964659
9Vitamin B6 metabolism_Homo sapiens_hsa007501.62252114
10Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.59840820
11Bile secretion_Homo sapiens_hsa049761.57642406
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.55914340
13Olfactory transduction_Homo sapiens_hsa047401.41849356
14mTOR signaling pathway_Homo sapiens_hsa041501.41617972
15Gastric acid secretion_Homo sapiens_hsa049711.38917779
16Circadian entrainment_Homo sapiens_hsa047131.38166908
17Glutamatergic synapse_Homo sapiens_hsa047241.35408924
18Synaptic vesicle cycle_Homo sapiens_hsa047211.34450941
19Fatty acid biosynthesis_Homo sapiens_hsa000611.33234530
20GABAergic synapse_Homo sapiens_hsa047271.32748193
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.31506695
22Type II diabetes mellitus_Homo sapiens_hsa049301.30950873
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.30353530
24Salivary secretion_Homo sapiens_hsa049701.25776372
25Estrogen signaling pathway_Homo sapiens_hsa049151.25248448
26Amphetamine addiction_Homo sapiens_hsa050311.19667512
27Biosynthesis of amino acids_Homo sapiens_hsa012301.18898599
28Nicotine addiction_Homo sapiens_hsa050331.18166914
29MicroRNAs in cancer_Homo sapiens_hsa052061.16336799
30Central carbon metabolism in cancer_Homo sapiens_hsa052301.14730121
31Glioma_Homo sapiens_hsa052141.14341493
32Dopaminergic synapse_Homo sapiens_hsa047281.13338328
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13261018
34Acute myeloid leukemia_Homo sapiens_hsa052211.12680825
35Inositol phosphate metabolism_Homo sapiens_hsa005621.12030880
36Oxytocin signaling pathway_Homo sapiens_hsa049211.11298824
37Insulin secretion_Homo sapiens_hsa049111.10925952
38Prostate cancer_Homo sapiens_hsa052151.10651550
39Gap junction_Homo sapiens_hsa045401.09397610
40Dilated cardiomyopathy_Homo sapiens_hsa054141.08778998
41GnRH signaling pathway_Homo sapiens_hsa049121.06375012
42Cholinergic synapse_Homo sapiens_hsa047251.06181077
43Lysine degradation_Homo sapiens_hsa003101.05324342
44Glucagon signaling pathway_Homo sapiens_hsa049221.04688745
45Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04413001
46Dorso-ventral axis formation_Homo sapiens_hsa043201.03109313
47Thyroid hormone signaling pathway_Homo sapiens_hsa049191.02868209
48Small cell lung cancer_Homo sapiens_hsa052221.02675586
49Morphine addiction_Homo sapiens_hsa050320.98632144
50Endometrial cancer_Homo sapiens_hsa052130.97902107
51Phenylalanine metabolism_Homo sapiens_hsa003600.97750532
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.97630973
53Renin secretion_Homo sapiens_hsa049240.97449365
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.95474773
55Carbon metabolism_Homo sapiens_hsa012000.95350637
56Longevity regulating pathway - mammal_Homo sapiens_hsa042110.95086392
57Pancreatic cancer_Homo sapiens_hsa052120.94685085
58Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.93424868
59Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.92934739
60Colorectal cancer_Homo sapiens_hsa052100.92647078
61Arginine and proline metabolism_Homo sapiens_hsa003300.92493966
62Fat digestion and absorption_Homo sapiens_hsa049750.91825706
63Insulin signaling pathway_Homo sapiens_hsa049100.91679180
64Proteoglycans in cancer_Homo sapiens_hsa052050.91429934
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.91234614
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90301193
67Butanoate metabolism_Homo sapiens_hsa006500.89564614
68cGMP-PKG signaling pathway_Homo sapiens_hsa040220.88519993
69ErbB signaling pathway_Homo sapiens_hsa040120.87813084
70Cocaine addiction_Homo sapiens_hsa050300.87792662
71mRNA surveillance pathway_Homo sapiens_hsa030150.86849138
72Non-small cell lung cancer_Homo sapiens_hsa052230.85408953
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.84905509
74Prion diseases_Homo sapiens_hsa050200.84328984
75Pentose phosphate pathway_Homo sapiens_hsa000300.82945379
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82755276
77VEGF signaling pathway_Homo sapiens_hsa043700.82254785
78Sulfur relay system_Homo sapiens_hsa041220.81890529
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.81443244
80Tight junction_Homo sapiens_hsa045300.80733467
81Vitamin digestion and absorption_Homo sapiens_hsa049770.80272046
82Fatty acid degradation_Homo sapiens_hsa000710.79961829
83AMPK signaling pathway_Homo sapiens_hsa041520.79929780
84Melanogenesis_Homo sapiens_hsa049160.79473340
85Fatty acid metabolism_Homo sapiens_hsa012120.77837581
86cAMP signaling pathway_Homo sapiens_hsa040240.77450268
87Long-term depression_Homo sapiens_hsa047300.77328718
88Insulin resistance_Homo sapiens_hsa049310.77125539
89Primary bile acid biosynthesis_Homo sapiens_hsa001200.76455889
90Focal adhesion_Homo sapiens_hsa045100.75021150
91Histidine metabolism_Homo sapiens_hsa003400.74910776
92Hippo signaling pathway_Homo sapiens_hsa043900.74743293
93Wnt signaling pathway_Homo sapiens_hsa043100.74267516
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.72247637
95Calcium signaling pathway_Homo sapiens_hsa040200.71924412
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.71416205
97Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71101595
98Oocyte meiosis_Homo sapiens_hsa041140.70957888
99Hedgehog signaling pathway_Homo sapiens_hsa043400.70177849
100Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69623785
101PPAR signaling pathway_Homo sapiens_hsa033200.69483087
102Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69077539
103Alcoholism_Homo sapiens_hsa050340.68637051
104Prolactin signaling pathway_Homo sapiens_hsa049170.68225787
105Thyroid hormone synthesis_Homo sapiens_hsa049180.67484716
106Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67114199
107Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.66073554
108FoxO signaling pathway_Homo sapiens_hsa040680.65455018
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.63916717
110Chronic myeloid leukemia_Homo sapiens_hsa052200.61088850
111Fructose and mannose metabolism_Homo sapiens_hsa000510.60837307
112Adipocytokine signaling pathway_Homo sapiens_hsa049200.60055129
113Axon guidance_Homo sapiens_hsa043600.59515680
114Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.59067072
115Pyruvate metabolism_Homo sapiens_hsa006200.58792268
116Bladder cancer_Homo sapiens_hsa052190.57675562
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.57525192
118Adherens junction_Homo sapiens_hsa045200.57033967
119Circadian rhythm_Homo sapiens_hsa047100.56950721
120Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56106488
121Galactose metabolism_Homo sapiens_hsa000520.55412446
122Basal cell carcinoma_Homo sapiens_hsa052170.55213891
123AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.54718040
124Melanoma_Homo sapiens_hsa052180.54701275
125Notch signaling pathway_Homo sapiens_hsa043300.54220140
126Renal cell carcinoma_Homo sapiens_hsa052110.54078312
127Propanoate metabolism_Homo sapiens_hsa006400.53994577
128Cell cycle_Homo sapiens_hsa041100.53766713
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.53593927
130Choline metabolism in cancer_Homo sapiens_hsa052310.53554910
131Cardiac muscle contraction_Homo sapiens_hsa042600.52855303
132TGF-beta signaling pathway_Homo sapiens_hsa043500.48724347
133Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46209983
134Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.44443803
135HIF-1 signaling pathway_Homo sapiens_hsa040660.44392321

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