CCDC92B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.59628476
2synaptic vesicle maturation (GO:0016188)6.14835847
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.91722979
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.46291724
5synaptic vesicle exocytosis (GO:0016079)5.32683508
6regulation of synaptic vesicle exocytosis (GO:2000300)5.32376039
7glutamate secretion (GO:0014047)5.18588720
8vocalization behavior (GO:0071625)5.12871525
9locomotory exploration behavior (GO:0035641)5.10361172
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.04465201
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.88662269
12regulation of synaptic vesicle transport (GO:1902803)4.72890828
13regulation of glutamate receptor signaling pathway (GO:1900449)4.71873425
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.56383047
15protein localization to synapse (GO:0035418)4.54936774
16neuromuscular synaptic transmission (GO:0007274)4.49806036
17neurotransmitter secretion (GO:0007269)4.47483168
18regulation of neuronal synaptic plasticity (GO:0048168)4.36324366
19neuronal action potential propagation (GO:0019227)4.35509728
20G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.34624883
21regulation of long-term neuronal synaptic plasticity (GO:0048169)4.34179422
22regulation of synapse structural plasticity (GO:0051823)4.33855114
23cellular response to electrical stimulus (GO:0071257)4.21663686
24behavioral response to nicotine (GO:0035095)4.21488004
25positive regulation of synapse maturation (GO:0090129)4.17454603
26synaptic transmission, glutamatergic (GO:0035249)4.16615202
27layer formation in cerebral cortex (GO:0021819)4.15935405
28neuron cell-cell adhesion (GO:0007158)4.14103348
29exploration behavior (GO:0035640)4.03386436
30neuron-neuron synaptic transmission (GO:0007270)4.02639748
31regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.00004134
32neuromuscular process controlling posture (GO:0050884)3.97009706
33glutamate receptor signaling pathway (GO:0007215)3.94396301
34neuronal ion channel clustering (GO:0045161)3.85836123
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.82423611
36neurotransmitter-gated ion channel clustering (GO:0072578)3.76315512
37gamma-aminobutyric acid transport (GO:0015812)3.75866209
38activation of protein kinase A activity (GO:0034199)3.75147937
39positive regulation of membrane potential (GO:0045838)3.74254370
40regulation of excitatory postsynaptic membrane potential (GO:0060079)3.74193144
41long-term memory (GO:0007616)3.67350001
42regulation of neurotransmitter secretion (GO:0046928)3.65048742
43neurotransmitter transport (GO:0006836)3.63062292
44cell migration in hindbrain (GO:0021535)3.62035664
45dendritic spine morphogenesis (GO:0060997)3.60017491
46regulation of postsynaptic membrane potential (GO:0060078)3.59050236
47membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.58326722
48cerebellar Purkinje cell differentiation (GO:0021702)3.57842326
49protoporphyrinogen IX metabolic process (GO:0046501)3.54982811
50positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.54576827
51neuromuscular process controlling balance (GO:0050885)3.52684472
52cellular potassium ion homeostasis (GO:0030007)3.51073742
53proline transport (GO:0015824)3.50611731
54synaptic vesicle endocytosis (GO:0048488)3.48608982
55regulation of synaptic plasticity (GO:0048167)3.46917816
56establishment of mitochondrion localization (GO:0051654)3.44889690
57glycine transport (GO:0015816)3.41967328
58positive regulation of neurotransmitter transport (GO:0051590)3.40857572
59detection of light stimulus involved in visual perception (GO:0050908)3.37326905
60detection of light stimulus involved in sensory perception (GO:0050962)3.37326905
61regulation of neurotransmitter transport (GO:0051588)3.35637584
62sodium ion export (GO:0071436)3.35588125
63regulation of neurotransmitter levels (GO:0001505)3.34606196
64establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.32772261
65mitochondrion transport along microtubule (GO:0047497)3.32772261
66regulation of dendritic spine morphogenesis (GO:0061001)3.31090407
67behavioral defense response (GO:0002209)3.29227262
68behavioral fear response (GO:0001662)3.29227262
69cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.26331565
70positive regulation of neurotransmitter secretion (GO:0001956)3.25824016
71neuron recognition (GO:0008038)3.25274865
72fear response (GO:0042596)3.21662642
73membrane depolarization during action potential (GO:0086010)3.20847008
74gamma-aminobutyric acid signaling pathway (GO:0007214)3.20211220
75behavioral response to cocaine (GO:0048148)3.19438034
76prepulse inhibition (GO:0060134)3.19409012
77auditory behavior (GO:0031223)3.18097021
78vesicle transport along microtubule (GO:0047496)3.17823584
79protein import into peroxisome matrix (GO:0016558)3.16881861
80protoporphyrinogen IX biosynthetic process (GO:0006782)3.15724526
81regulation of gene silencing by RNA (GO:0060966)3.15319886
82regulation of posttranscriptional gene silencing (GO:0060147)3.15319886
83regulation of gene silencing by miRNA (GO:0060964)3.15319886
84transmission of nerve impulse (GO:0019226)3.14714144
85long-term synaptic potentiation (GO:0060291)3.12851535
86chemosensory behavior (GO:0007635)3.12741470
87spinal cord association neuron differentiation (GO:0021527)3.12671834
88response to histamine (GO:0034776)3.11905966
89central nervous system myelination (GO:0022010)3.10743696
90axon ensheathment in central nervous system (GO:0032291)3.10743696
91membrane hyperpolarization (GO:0060081)3.10005048
92positive regulation of gastrulation (GO:2000543)3.09978703
93regulation of synapse maturation (GO:0090128)3.09854844
94positive regulation of synaptic transmission, GABAergic (GO:0032230)3.08629681
95regulation of synaptic transmission, glutamatergic (GO:0051966)3.07945178
96membrane depolarization (GO:0051899)3.07312273
97regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.07006423
98positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.05518173
99regulation of vesicle fusion (GO:0031338)3.05156723
100pyrimidine nucleobase catabolic process (GO:0006208)3.03928580
101cell communication by electrical coupling (GO:0010644)3.03713623
102negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.02323428
103social behavior (GO:0035176)3.02268829
104intraspecies interaction between organisms (GO:0051703)3.02268829
105positive regulation of dendritic spine morphogenesis (GO:0061003)2.97767003
106regulation of calcium ion-dependent exocytosis (GO:0017158)2.97650295
107response to dietary excess (GO:0002021)2.97587887
108axonal fasciculation (GO:0007413)2.96873298
109neuromuscular process (GO:0050905)2.95604824
110synaptic transmission (GO:0007268)2.95179797
111presynaptic membrane assembly (GO:0097105)2.93749469
112presynaptic membrane organization (GO:0097090)2.93038982
113mechanosensory behavior (GO:0007638)2.92970517
114postsynaptic membrane organization (GO:0001941)2.92910048
115negative regulation of synaptic transmission, GABAergic (GO:0032229)2.92595453
116positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.91438839
117substrate-independent telencephalic tangential migration (GO:0021826)2.89866329
118substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.89866329
119dendrite morphogenesis (GO:0048813)2.89650953
120cerebellar granule cell differentiation (GO:0021707)2.89260715
121adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.89183303
122dopamine receptor signaling pathway (GO:0007212)2.88929045
123response to auditory stimulus (GO:0010996)2.87549839
124adult walking behavior (GO:0007628)2.87100975
125synapse assembly (GO:0007416)2.86058656
126retinal cone cell development (GO:0046549)2.85320178
127L-serine metabolic process (GO:0006563)2.83994814
128stress granule assembly (GO:0034063)2.81239323
129somite rostral/caudal axis specification (GO:0032525)2.80327126
130regulation of sensory perception (GO:0051931)2.79908922
131regulation of sensory perception of pain (GO:0051930)2.79908922
132histone arginine methylation (GO:0034969)2.79325804
133neurofilament cytoskeleton organization (GO:0060052)2.78616572
134cell fate commitment involved in formation of primary germ layer (GO:0060795)2.74046625
135peristalsis (GO:0030432)2.71036876
136DNA replication checkpoint (GO:0000076)2.69942378
137sensory perception of pain (GO:0019233)2.68637752
138histone H4-K12 acetylation (GO:0043983)2.63030491
139mating behavior (GO:0007617)2.61210969
140mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.60858829
141positive regulation of mitochondrial fission (GO:0090141)2.59579193
142urinary tract smooth muscle contraction (GO:0014848)2.59478229
143DNA damage response, detection of DNA damage (GO:0042769)2.57248365
144regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.57079405
145cell differentiation in hindbrain (GO:0021533)2.51505722
146protein localization to peroxisome (GO:0072662)2.50856326
147protein targeting to peroxisome (GO:0006625)2.50856326
148establishment of protein localization to peroxisome (GO:0072663)2.50856326
149innervation (GO:0060384)2.50037569
150RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.49872314
151tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.49872314
152phosphate ion homeostasis (GO:0055062)2.48382063
153trivalent inorganic anion homeostasis (GO:0072506)2.48382063

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.36794953
2REST_21632747_ChIP-Seq_MESCs_Mouse3.46451078
3RARB_27405468_Chip-Seq_BRAIN_Mouse3.33627166
4GBX2_23144817_ChIP-Seq_PC3_Human3.11326065
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95859298
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.85165098
7REST_18959480_ChIP-ChIP_MESCs_Mouse2.84742957
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.76006386
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.62578833
10DROSHA_22980978_ChIP-Seq_HELA_Human2.55811070
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.55493866
12SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.48985582
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.48958729
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47625051
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.44143236
16RNF2_18974828_ChIP-Seq_MESCs_Mouse2.42773648
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.42773648
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32527136
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.24719362
20MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.23589708
21EZH2_27304074_Chip-Seq_ESCs_Mouse2.18045804
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16741824
23SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.15263224
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.11862706
25EZH2_27294783_Chip-Seq_ESCs_Mouse2.10223466
26ERG_21242973_ChIP-ChIP_JURKAT_Human2.08720929
27IKZF1_21737484_ChIP-ChIP_HCT116_Human2.06720382
28RNF2_27304074_Chip-Seq_ESCs_Mouse2.02717994
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.96001867
30XRN2_22483619_ChIP-Seq_HELA_Human1.95117803
31RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.87388593
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.71280626
33DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.71038811
34KDM2B_26808549_Chip-Seq_K562_Human1.62563796
35KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.60035837
36KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.60035837
37KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.60035837
38RBPJ_22232070_ChIP-Seq_NCS_Mouse1.58163675
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57674350
40KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.53712855
41NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.53263039
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53173199
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.47977846
44ZNF274_21170338_ChIP-Seq_K562_Hela1.47905601
45DNAJC2_21179169_ChIP-ChIP_NT2_Human1.47346988
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.45681104
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.45576411
48E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42831565
49ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.40189416
50HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.38936267
51SMAD4_21799915_ChIP-Seq_A2780_Human1.38546141
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.37251742
53EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.35998430
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35369923
55GABP_17652178_ChIP-ChIP_JURKAT_Human1.33794446
56CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.33601267
57MYC_18555785_ChIP-Seq_MESCs_Mouse1.32252782
58GATA1_19941826_ChIP-Seq_K562_Human1.30500621
59MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29103100
60JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.27824741
61RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.27244132
62FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.27084211
63TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.26891637
64GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.26424130
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.26138369
66PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.25730087
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.25089355
68RING1B_27294783_Chip-Seq_ESCs_Mouse1.25033483
69AR_19668381_ChIP-Seq_PC3_Human1.23102905
70P68_20966046_ChIP-Seq_HELA_Human1.21747935
71CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.21264146
72FOXP1_21924763_ChIP-Seq_HESCs_Human1.21021495
73TET1_21490601_ChIP-Seq_MESCs_Mouse1.18697476
74KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.18422520
75ZNF263_19887448_ChIP-Seq_K562_Human1.16625654
76AR_21572438_ChIP-Seq_LNCaP_Human1.16161479
77RING1B_27294783_Chip-Seq_NPCs_Mouse1.15406858
78SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13851039
79STAT3_23295773_ChIP-Seq_U87_Human1.13530113
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.12927068
81NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.11525603
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.11456076
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10937623
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10824123
85SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.10487915
86TAF15_26573619_Chip-Seq_HEK293_Human1.09298601
87YY1_22570637_ChIP-Seq_MALME-3M_Human1.08477480
88BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.08302881
89ZFP281_27345836_Chip-Seq_ESCs_Mouse1.08230268
90ETS1_20019798_ChIP-Seq_JURKAT_Human1.07367614
91MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.06832751
92POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.06731642
93SOX2_16153702_ChIP-ChIP_HESCs_Human1.06603979
94YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06595513
95P53_22127205_ChIP-Seq_FIBROBLAST_Human1.06498655
96RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.05650245
97MYC_18358816_ChIP-ChIP_MESCs_Mouse1.05319932
98CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.04611868
99WT1_25993318_ChIP-Seq_PODOCYTE_Human1.03580482
100CTCF_27219007_Chip-Seq_Bcells_Human1.03124681
101SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02853110
102SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02168687
103GATA1_26923725_Chip-Seq_HPCs_Mouse1.02146065
104SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.01793900
105SMAD3_21741376_ChIP-Seq_EPCs_Human1.01290711
106SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.01067754
107FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.00531553
108GABP_19822575_ChIP-Seq_HepG2_Human1.00472392
109SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00341370
110ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.99642932
111EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99301770
112CTCF_20526341_ChIP-Seq_ESCs_Human0.98555431
113WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98325294
114PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.97698658
115TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97590208
116BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97268194
117PHF8_20622854_ChIP-Seq_HELA_Human0.96094999
118TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95896181
119E2F1_20622854_ChIP-Seq_HELA_Human0.95432171
120TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.94656650
121SMAD3_21741376_ChIP-Seq_ESCs_Human0.94556478
122CBX2_27304074_Chip-Seq_ESCs_Mouse0.94241984
123SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.94213644
124ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93707298
125CREB1_26743006_Chip-Seq_LNCaP_Human0.92986946
126RNF2_27304074_Chip-Seq_NSC_Mouse0.92744311
127P53_21459846_ChIP-Seq_SAOS-2_Human0.92569908
128SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92192953
129SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90693062
130OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89960812
131TET1_21451524_ChIP-Seq_MESCs_Mouse0.89940366
132TCF4_23295773_ChIP-Seq_U87_Human0.89727981
133DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88835207
134AR_25329375_ChIP-Seq_VCAP_Human0.88657945
135PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.88151717
136SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.87651715
137POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.87184312
138P300_19829295_ChIP-Seq_ESCs_Human0.87079950
139MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.86203982
140SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.85999781
141OCT4_19829295_ChIP-Seq_ESCs_Human0.85269238
142CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.84981135
143NELFA_20434984_ChIP-Seq_ESCs_Mouse0.84692374
144PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.84567495
145MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.84499894
146TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83919481
147GATA1_19941827_ChIP-Seq_MEL_Mouse0.83517223
148CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82677797
149TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.82541436
150KLF4_19829295_ChIP-Seq_ESCs_Human0.81542380
151GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.80724391
152SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78946261
153ZFP57_27257070_Chip-Seq_ESCs_Mouse0.78902405

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.42984314
2MP0003880_abnormal_central_pattern4.14959749
3MP0003635_abnormal_synaptic_transmissio4.03463811
4MP0004270_analgesia3.58805767
5MP0002063_abnormal_learning/memory/cond3.21228483
6MP0009745_abnormal_behavioral_response3.14645216
7MP0009046_muscle_twitch2.98223170
8MP0002064_seizures2.97096596
9MP0002822_catalepsy2.91449932
10MP0001968_abnormal_touch/_nociception2.89658183
11MP0002572_abnormal_emotion/affect_behav2.66439277
12MP0002734_abnormal_mechanical_nocicepti2.65929894
13MP0002272_abnormal_nervous_system2.53193672
14MP0005423_abnormal_somatic_nervous2.42471059
15MP0001486_abnormal_startle_reflex2.34727106
16MP0002909_abnormal_adrenal_gland2.32154948
17MP0002735_abnormal_chemical_nociception2.19003359
18MP0001501_abnormal_sleep_pattern2.16847247
19MP0002733_abnormal_thermal_nociception2.16386309
20MP0002736_abnormal_nociception_after2.15244139
21MP0001984_abnormal_olfaction2.05628607
22MP0001440_abnormal_grooming_behavior2.01371084
23MP0001970_abnormal_pain_threshold1.97844475
24MP0003656_abnormal_erythrocyte_physiolo1.95227392
25MP0002067_abnormal_sensory_capabilities1.92878063
26MP0004811_abnormal_neuron_physiology1.87421498
27MP0004133_heterotaxia1.79618746
28MP0004147_increased_porphyrin_level1.77313234
29MP0002184_abnormal_innervation1.77184627
30MP0003879_abnormal_hair_cell1.76858731
31MP0008569_lethality_at_weaning1.72896087
32MP0004858_abnormal_nervous_system1.72730724
33MP0002557_abnormal_social/conspecific_i1.68163477
34MP0009780_abnormal_chondrocyte_physiolo1.67484644
35MP0004924_abnormal_behavior1.63694242
36MP0005386_behavior/neurological_phenoty1.63694242
37MP0005646_abnormal_pituitary_gland1.54284167
38MP0003787_abnormal_imprinting1.53253589
39MP0005645_abnormal_hypothalamus_physiol1.52186513
40MP0002254_reproductive_system_inflammat1.51698453
41MP0000955_abnormal_spinal_cord1.50633560
42MP0000778_abnormal_nervous_system1.48431565
43MP0006276_abnormal_autonomic_nervous1.47763459
44MP0003329_amyloid_beta_deposits1.45152962
45MP0002882_abnormal_neuron_morphology1.41042951
46MP0002160_abnormal_reproductive_system1.40784517
47MP0002066_abnormal_motor_capabilities/c1.38498431
48MP0001529_abnormal_vocalization1.38065512
49MP0004885_abnormal_endolymph1.32968999
50MP0003283_abnormal_digestive_organ1.29509906
51MP0003122_maternal_imprinting1.24488136
52MP0005171_absent_coat_pigmentation1.23075967
53MP0005394_taste/olfaction_phenotype1.19532096
54MP0005499_abnormal_olfactory_system1.19532096
55MP0003693_abnormal_embryo_hatching1.18925291
56MP0003633_abnormal_nervous_system1.18439282
57MP0004957_abnormal_blastocyst_morpholog1.17907970
58MP0003123_paternal_imprinting1.17122029
59MP0008872_abnormal_physiological_respon1.15144921
60MP0002152_abnormal_brain_morphology1.13062388
61MP0008877_abnormal_DNA_methylation1.12925887
62MP0002638_abnormal_pupillary_reflex1.12429921
63MP0001188_hyperpigmentation1.12388349
64MP0000013_abnormal_adipose_tissue1.11844767
65MP0003136_yellow_coat_color1.11798558
66MP0003011_delayed_dark_adaptation1.09697446
67MP0001919_abnormal_reproductive_system1.09116042
68MP0001986_abnormal_taste_sensitivity1.07773944
69MP0003137_abnormal_impulse_conducting1.07418852
70MP0004142_abnormal_muscle_tone1.06182808
71MP0001502_abnormal_circadian_rhythm1.03785500
72MP0002229_neurodegeneration1.00316421
73MP0003631_nervous_system_phenotype1.00027247
74MP0001905_abnormal_dopamine_level0.99133789
75MP0001348_abnormal_lacrimal_gland0.96005471
76MP0004085_abnormal_heartbeat0.95698117
77MP0000538_abnormal_urinary_bladder0.95109943
78MP0004043_abnormal_pH_regulation0.94697965
79MP0002069_abnormal_eating/drinking_beha0.94268664
80MP0008961_abnormal_basal_metabolism0.93809141
81MP0004145_abnormal_muscle_electrophysio0.93792813
82MP0010386_abnormal_urinary_bladder0.92011916
83MP0005551_abnormal_eye_electrophysiolog0.90220384
84MP0002653_abnormal_ependyma_morphology0.85142387
85MP0000631_abnormal_neuroendocrine_gland0.83659883
86MP0008874_decreased_physiological_sensi0.81729091
87MP0008004_abnormal_stomach_pH0.81507129
88MP0009672_abnormal_birth_weight0.79756585
89MP0006072_abnormal_retinal_apoptosis0.79530827
90MP0001177_atelectasis0.79430328
91MP0003698_abnormal_male_reproductive0.79365502
92MP0005535_abnormal_body_temperature0.79345917
93MP0002210_abnormal_sex_determination0.79059188
94MP0000462_abnormal_digestive_system0.77775135
95MP0002752_abnormal_somatic_nervous0.77275243
96MP0005187_abnormal_penis_morphology0.76330376
97MP0001485_abnormal_pinna_reflex0.75317193
98MP0005389_reproductive_system_phenotype0.75310801
99MP0005174_abnormal_tail_pigmentation0.74168033
100MP0000678_abnormal_parathyroid_gland0.73208766
101MP0003567_abnormal_fetal_cardiomyocyte0.72820432
102MP0003938_abnormal_ear_development0.72399873
103MP0001963_abnormal_hearing_physiology0.70757289
104MP0005253_abnormal_eye_physiology0.69873144
105MP0002928_abnormal_bile_duct0.69304462
106MP0005409_darkened_coat_color0.69238815
107MP0003634_abnormal_glial_cell0.69003648
108MP0003632_abnormal_nervous_system0.68645101
109MP0003861_abnormal_nervous_system0.68611914
110MP0002837_dystrophic_cardiac_calcinosis0.68260843
111MP0006292_abnormal_olfactory_placode0.67242859
112MP0002751_abnormal_autonomic_nervous0.64761539
113MP0010769_abnormal_survival0.63227458
114MP0001145_abnormal_male_reproductive0.62291339
115MP0008875_abnormal_xenobiotic_pharmacok0.62244429
116MP0004742_abnormal_vestibular_system0.61218463
117MP0010768_mortality/aging0.60735016
118MP0000639_abnormal_adrenal_gland0.60320462
119MP0002081_perinatal_lethality0.60149823
120MP0002082_postnatal_lethality0.59857015
121MP0010770_preweaning_lethality0.59857015
122MP0004233_abnormal_muscle_weight0.59289343
123MP0004215_abnormal_myocardial_fiber0.58436093
124MP0003890_abnormal_embryonic-extraembry0.55586599
125MP0003956_abnormal_body_size0.55070328
126MP0003121_genomic_imprinting0.54897067
127MP0003119_abnormal_digestive_system0.54829547
128MP0000751_myopathy0.54523807
129MP0001299_abnormal_eye_distance/0.54021332
130MP0003075_altered_response_to0.53760157
131MP0002234_abnormal_pharynx_morphology0.53368295

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.01019760
2Myokymia (HP:0002411)6.27387570
3Visual hallucinations (HP:0002367)5.52582405
4Focal seizures (HP:0007359)5.41850416
5Epileptic encephalopathy (HP:0200134)4.48176928
6Atonic seizures (HP:0010819)4.43059551
7Febrile seizures (HP:0002373)4.24845899
8Absence seizures (HP:0002121)3.98148368
9Progressive cerebellar ataxia (HP:0002073)3.85968555
10Cortical dysplasia (HP:0002539)3.82526832
11Dialeptic seizures (HP:0011146)3.78694807
12Generalized tonic-clonic seizures (HP:0002069)3.78347767
13Action tremor (HP:0002345)3.74459174
14Abnormal pancreas size (HP:0012094)3.70311755
15Depression (HP:0000716)3.48728907
16Birth length less than 3rd percentile (HP:0003561)3.33609788
17Poikilocytosis (HP:0004447)3.31718413
18Poor eye contact (HP:0000817)3.18418335
19Broad-based gait (HP:0002136)3.13255395
20Anxiety (HP:0000739)3.09758843
21Abnormality of the lower motor neuron (HP:0002366)3.07182943
22Gaze-evoked nystagmus (HP:0000640)3.03575363
23Insomnia (HP:0100785)3.02895087
24Abnormal social behavior (HP:0012433)3.00057840
25Impaired social interactions (HP:0000735)3.00057840
26Supranuclear gaze palsy (HP:0000605)2.99381968
27Ankle clonus (HP:0011448)2.98696007
28Truncal ataxia (HP:0002078)2.96513432
29Impaired smooth pursuit (HP:0007772)2.96126017
30Polyphagia (HP:0002591)2.94713156
31Impaired vibration sensation in the lower limbs (HP:0002166)2.94299359
32Rib fusion (HP:0000902)2.93231438
33Abnormality of the heme biosynthetic pathway (HP:0010472)2.93171180
34Hypochromic microcytic anemia (HP:0004840)2.86947886
35Amblyopia (HP:0000646)2.86610448
36Long foot (HP:0001833)2.85286892
37Postural instability (HP:0002172)2.84290613
38Dysdiadochokinesis (HP:0002075)2.83157922
39Delusions (HP:0000746)2.77555735
40Papilledema (HP:0001085)2.76297140
41Urinary bladder sphincter dysfunction (HP:0002839)2.75991785
42Ventricular fibrillation (HP:0001663)2.74808274
43Septo-optic dysplasia (HP:0100842)2.66835656
44Akinesia (HP:0002304)2.64760665
45Esotropia (HP:0000565)2.62449088
46Epileptiform EEG discharges (HP:0011182)2.60560299
47Genetic anticipation (HP:0003743)2.55538000
48Poor suck (HP:0002033)2.54612778
49EEG with generalized epileptiform discharges (HP:0011198)2.53647040
50Dysmetria (HP:0001310)2.52568297
51Abnormal eating behavior (HP:0100738)2.48766351
52Hemiparesis (HP:0001269)2.48701305
53Generalized hypotonia (HP:0001290)2.47768168
54Bradykinesia (HP:0002067)2.47523241
55Increased hepatocellular lipid droplets (HP:0006565)2.47296746
56Epiphyseal stippling (HP:0010655)2.46108823
57Abnormality of ocular smooth pursuit (HP:0000617)2.46108218
58Hypsarrhythmia (HP:0002521)2.45075137
59Lipid accumulation in hepatocytes (HP:0006561)2.42299876
60Hyperventilation (HP:0002883)2.41631713
61Testicular atrophy (HP:0000029)2.41607331
62Turricephaly (HP:0000262)2.40818721
63Spastic gait (HP:0002064)2.37782131
64Abnormal hair whorl (HP:0010721)2.36998974
65Maternal diabetes (HP:0009800)2.36339459
66Excessive salivation (HP:0003781)2.36005642
67Drooling (HP:0002307)2.36005642
68Annular pancreas (HP:0001734)2.35919927
69Sleep apnea (HP:0010535)2.35602594
70Retinal dysplasia (HP:0007973)2.35504166
71Hypoplasia of the brainstem (HP:0002365)2.35188087
72Aplasia/Hypoplasia of the brainstem (HP:0007362)2.35188087
73Urinary urgency (HP:0000012)2.34002962
74Global brain atrophy (HP:0002283)2.33438740
75Insidious onset (HP:0003587)2.33007812
76Termporal pattern (HP:0011008)2.33007812
77Limb dystonia (HP:0002451)2.29042073
78Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.28229948
79Mutism (HP:0002300)2.26535608
80Decreased muscle mass (HP:0003199)2.26082418
81Agitation (HP:0000713)2.25986812
82Absent speech (HP:0001344)2.24463647
83Bundle branch block (HP:0011710)2.24231710
84Diplopia (HP:0000651)2.23637968
85Abnormality of binocular vision (HP:0011514)2.23637968
86Status epilepticus (HP:0002133)2.21818706
87Type 2 muscle fiber atrophy (HP:0003554)2.20840341
88Bony spicule pigmentary retinopathy (HP:0007737)2.20656641
89Reticulocytosis (HP:0001923)2.16286643
90Pheochromocytoma (HP:0002666)2.15960657
91Upper limb muscle weakness (HP:0003484)2.15513958
92Hemiplegia (HP:0002301)2.15205589
93Brushfield spots (HP:0001088)2.14952211
94Shawl scrotum (HP:0000049)2.14624388
95Pendular nystagmus (HP:0012043)2.14500407
96Intention tremor (HP:0002080)2.13499027
97Torticollis (HP:0000473)2.13032954
98Muscle fiber atrophy (HP:0100295)2.12482801
99Optic nerve hypoplasia (HP:0000609)2.12359881
100Stereotypic behavior (HP:0000733)2.12302145
101Dysmetric saccades (HP:0000641)2.11474427
102Acanthocytosis (HP:0001927)2.09717271
103Vertebral clefting (HP:0008428)2.09119431
104Attenuation of retinal blood vessels (HP:0007843)2.06747143
105Hypogonadotrophic hypogonadism (HP:0000044)2.06433180
106Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.05580877
107Abnormal epiphyseal ossification (HP:0010656)2.05505739
108Aplasia/Hypoplasia of the spleen (HP:0010451)2.03560881
109Supernumerary spleens (HP:0009799)2.01799882
110Progressive inability to walk (HP:0002505)2.00196178
111Restlessness (HP:0000711)1.97919877
112Narrow nasal bridge (HP:0000446)1.97141508
113Asplenia (HP:0001746)1.95627248
114Abnormality of the corticospinal tract (HP:0002492)1.95423275
115Failure to thrive in infancy (HP:0001531)1.95025234
116Focal dystonia (HP:0004373)1.94589680
117Cerebral inclusion bodies (HP:0100314)1.92748274
118Resting tremor (HP:0002322)1.89892373
119Amyotrophic lateral sclerosis (HP:0007354)1.89762660
120Scanning speech (HP:0002168)1.88860248
121Pointed chin (HP:0000307)1.87602650
122Abnormality of the labia minora (HP:0012880)1.87120471
123Clonus (HP:0002169)1.86976276
124Lower limb muscle weakness (HP:0007340)1.86895228
125Impaired vibratory sensation (HP:0002495)1.86198536
126Myotonia (HP:0002486)1.86080856
127Cerebral hypomyelination (HP:0006808)1.84073073
128Hypercortisolism (HP:0001578)1.83241722
129Abnormal lung lobation (HP:0002101)1.82521804
130Cholelithiasis (HP:0001081)1.82239706
131Deep palmar crease (HP:0006191)1.81944664
132Anosmia (HP:0000458)1.80951359
133Neuroendocrine neoplasm (HP:0100634)1.79777841
134Dysphonia (HP:0001618)1.79137236
135Absent septum pellucidum (HP:0001331)1.79001101
136Psychosis (HP:0000709)1.78659590
137Megalencephaly (HP:0001355)1.78077427
138Incomplete penetrance (HP:0003829)1.78024507
139Unilateral renal agenesis (HP:0000122)1.77476184
140Gait ataxia (HP:0002066)1.76277860
141Inability to walk (HP:0002540)1.75568108
142Choreoathetosis (HP:0001266)1.75506717
143Abnormality of saccadic eye movements (HP:0000570)1.74361010
144Double outlet right ventricle (HP:0001719)1.74248728
145Congenital malformation of the right heart (HP:0011723)1.74248728
146Patellar aplasia (HP:0006443)1.73602541
147Craniofacial dystonia (HP:0012179)1.73447375
148Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.73346678
149Pachygyria (HP:0001302)1.72993861
150Abnormal EKG (HP:0003115)1.72708007
151Fetal akinesia sequence (HP:0001989)1.72489290
152Abnormality of the labia (HP:0000058)1.71857652
153Absent radius (HP:0003974)1.71115839
154Protruding tongue (HP:0010808)1.70882644
155Spastic tetraplegia (HP:0002510)1.68996715
156Anomalous pulmonary venous return (HP:0010772)1.68886413
157Broad distal phalanx of finger (HP:0009836)1.68809299
158Breast aplasia (HP:0100783)1.68060917
159Tetraplegia (HP:0002445)1.68053317
160Abnormality of the astrocytes (HP:0100707)1.68035780
161Myelomeningocele (HP:0002475)1.66884300
162Choanal stenosis (HP:0000452)1.66614934
163Neonatal onset (HP:0003623)1.65095222
164Prolonged partial thromboplastin time (HP:0003645)1.64834668
165Labial hypoplasia (HP:0000066)1.64364549
166Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.64284430
167Renal Fanconi syndrome (HP:0001994)1.63378275
168Type II lissencephaly (HP:0007260)1.62835100
169Mesangial abnormality (HP:0001966)1.62696685

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K25.92508539
2NTRK34.61894682
3EPHA44.33150985
4MAP3K94.06002960
5MAP3K42.87031455
6DAPK22.81155793
7MARK12.75508892
8CDC72.62362330
9WNK42.60309820
10MAPK152.49444706
11MINK12.48257609
12DYRK22.39713240
13PAK62.15475659
14MAP2K72.14630652
15PRKD32.13734161
16TRIM282.09469247
17CAMKK12.02183840
18KSR21.94420764
19NTRK11.91086397
20CAMKK21.89135851
21GRK51.82214255
22DAPK11.78804493
23NTRK21.77353077
24PNCK1.75342447
25CAMK1D1.73997808
26SRPK11.71266137
27CASK1.70646203
28DYRK31.66521644
29AKT31.59945482
30MAP2K41.59327787
31RIPK41.57914932
32CDK51.54722594
33ACVR1B1.45975816
34ARAF1.45150517
35MAP3K21.44468385
36KSR11.41080811
37UHMK11.40676867
38STK161.40076915
39BCR1.35101628
40BRSK11.31726548
41PRKCG1.26791190
42CDK191.26085872
43NEK11.24392110
44TTK1.23361222
45STK381.23041858
46TAOK11.21197896
47PLK21.18291884
48ALK1.15136192
49MAP3K121.12627345
50SIK21.12189316
51BMX1.09166469
52CSNK1G31.08260280
53BCKDK1.07986347
54PLK41.06905459
55BRAF1.03106412
56SGK2231.00667017
57SGK4941.00667017
58STK111.00126536
59SCYL20.99677914
60BMPR1B0.93597512
61TYRO30.92799017
62FES0.91841934
63LATS20.91784318
64DYRK1B0.90635147
65MAPK130.90294028
66CDK180.89963275
67CSNK1G10.89658328
68CDK150.89576941
69SGK20.89293974
70PASK0.88065895
71CDK140.86954501
72DYRK1A0.83363910
73BUB10.82732331
74SGK30.81017266
75CAMK2A0.80505720
76CDK11A0.80432038
77RET0.77575443
78PINK10.77311815
79CAMK10.75433498
80CAMK2B0.74263128
81TSSK60.73244007
82PLK10.72756784
83CDC42BPA0.72737215
84SGK10.70740160
85AURKA0.70591739
86CSNK1G20.67868993
87CSNK1A1L0.67434528
88PHKG20.66482475
89PHKG10.66482475
90CAMK1G0.66100300
91NEK20.66072943
92TNIK0.63168999
93PRKCH0.62046307
94PAK30.60620524
95RPS6KA50.59521438
96WNK10.57762243
97TESK20.57615181
98RAF10.57455116
99PDPK10.57082301
100RPS6KA30.56373703
101PAK10.55211567
102MAP3K10.54957040
103PKN10.54901184
104MAP2K10.54290630
105PDK10.53351201
106ATR0.52895299
107CCNB10.52881754
108PRPF4B0.50868643
109ADRBK10.50440368
110ADRBK20.48317057
111WNK30.47832661
112EIF2AK10.47077762
113MARK20.46667419
114CSNK1E0.46076756
115NME10.45633906
116MUSK0.45418840
117MAPK100.45351439
118PTK2B0.44793788
119PLK30.43438617
120DAPK30.42875365
121OXSR10.42554377
122ZAK0.42248760
123TAOK20.41807474
124ERBB20.41439270
125RIPK10.41319314
126MATK0.39533664
127RPS6KA20.38961902
128CHEK20.38044122
129PRKCZ0.37912027
130CAMK2G0.37747158
131PRKAA10.37639261
132PRKCI0.36045749
133PTK20.35857923
134CAMK40.35310725
135MAPK80.35233407
136ICK0.34808761
137BMPR20.33969932
138RPS6KA10.33855007
139PRKDC0.33742203
140PRKCB0.33741896
141CSNK1A10.33613790
142PRKACG0.33447632
143GRK10.33440550
144GSK3B0.33377420
145FER0.31770698
146CAMK2D0.31542936

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.55449600
2Synaptic vesicle cycle_Homo sapiens_hsa047213.54746476
3Olfactory transduction_Homo sapiens_hsa047403.26384636
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.92058860
5Steroid biosynthesis_Homo sapiens_hsa001002.90708524
6Long-term potentiation_Homo sapiens_hsa047202.73390248
7GABAergic synapse_Homo sapiens_hsa047272.71438944
8Circadian entrainment_Homo sapiens_hsa047132.62270587
9Amphetamine addiction_Homo sapiens_hsa050312.58321888
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.50203531
11Morphine addiction_Homo sapiens_hsa050322.47702224
12Glutamatergic synapse_Homo sapiens_hsa047242.45400316
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.40492391
14Insulin secretion_Homo sapiens_hsa049112.32398343
15Dopaminergic synapse_Homo sapiens_hsa047282.27080907
16Protein export_Homo sapiens_hsa030602.07858387
17Salivary secretion_Homo sapiens_hsa049702.05979443
18Taste transduction_Homo sapiens_hsa047421.91673786
19Cholinergic synapse_Homo sapiens_hsa047251.85864925
20Collecting duct acid secretion_Homo sapiens_hsa049661.82398607
21Oxidative phosphorylation_Homo sapiens_hsa001901.77177668
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.76822746
23Cocaine addiction_Homo sapiens_hsa050301.74621727
24Gastric acid secretion_Homo sapiens_hsa049711.67646381
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.64729488
26Long-term depression_Homo sapiens_hsa047301.62190580
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60521609
28Parkinsons disease_Homo sapiens_hsa050121.58786177
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.56446123
30Vitamin B6 metabolism_Homo sapiens_hsa007501.55582031
31Serotonergic synapse_Homo sapiens_hsa047261.55071975
32Oxytocin signaling pathway_Homo sapiens_hsa049211.52367683
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.51842130
34Renin secretion_Homo sapiens_hsa049241.48700246
35Type II diabetes mellitus_Homo sapiens_hsa049301.45397172
36GnRH signaling pathway_Homo sapiens_hsa049121.43211799
37Calcium signaling pathway_Homo sapiens_hsa040201.40002232
38Gap junction_Homo sapiens_hsa045401.38362032
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.37952396
40Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.36653599
41Oocyte meiosis_Homo sapiens_hsa041141.34809589
42Biosynthesis of amino acids_Homo sapiens_hsa012301.32470788
43Selenocompound metabolism_Homo sapiens_hsa004501.27549905
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26597982
45Estrogen signaling pathway_Homo sapiens_hsa049151.22570696
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22004459
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.20006709
48cAMP signaling pathway_Homo sapiens_hsa040241.19615281
49Glioma_Homo sapiens_hsa052141.14368744
50Alcoholism_Homo sapiens_hsa050341.10877205
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10162875
52Huntingtons disease_Homo sapiens_hsa050161.07867504
53Phototransduction_Homo sapiens_hsa047441.06975673
54Sulfur relay system_Homo sapiens_hsa041221.06107989
55RNA polymerase_Homo sapiens_hsa030201.05588958
56Alzheimers disease_Homo sapiens_hsa050101.03003690
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02411857
58Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.01545102
59Dorso-ventral axis formation_Homo sapiens_hsa043201.00364005
60Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99861383
61Vibrio cholerae infection_Homo sapiens_hsa051100.99321445
62cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97392135
63Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.93987165
64ErbB signaling pathway_Homo sapiens_hsa040120.93804514
65Fanconi anemia pathway_Homo sapiens_hsa034600.93102902
66Melanogenesis_Homo sapiens_hsa049160.92760711
67Arginine and proline metabolism_Homo sapiens_hsa003300.90211904
68mTOR signaling pathway_Homo sapiens_hsa041500.89830595
69Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.89164971
70Pancreatic secretion_Homo sapiens_hsa049720.88390932
71Fatty acid elongation_Homo sapiens_hsa000620.86542604
72Folate biosynthesis_Homo sapiens_hsa007900.85335064
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84683169
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84473597
75Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.84341756
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.83138125
77Circadian rhythm_Homo sapiens_hsa047100.83120284
78Thyroid hormone synthesis_Homo sapiens_hsa049180.81986013
79RNA degradation_Homo sapiens_hsa030180.80550151
80Axon guidance_Homo sapiens_hsa043600.76568251
81Base excision repair_Homo sapiens_hsa034100.76335226
82Cardiac muscle contraction_Homo sapiens_hsa042600.75237368
83Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.75055622
84RNA transport_Homo sapiens_hsa030130.74403999
85Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69975380
86Choline metabolism in cancer_Homo sapiens_hsa052310.69162398
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.68957425
88MAPK signaling pathway_Homo sapiens_hsa040100.66873157
89Hippo signaling pathway_Homo sapiens_hsa043900.66585881
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66081426
91Propanoate metabolism_Homo sapiens_hsa006400.65454076
92Regulation of autophagy_Homo sapiens_hsa041400.64530699
93Endometrial cancer_Homo sapiens_hsa052130.64182384
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63934454
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63305433
96Glucagon signaling pathway_Homo sapiens_hsa049220.63190547
97Non-small cell lung cancer_Homo sapiens_hsa052230.62255375
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60853412
99Hedgehog signaling pathway_Homo sapiens_hsa043400.59891009
100Nitrogen metabolism_Homo sapiens_hsa009100.59620759
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.59244570
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58602067
103Cyanoamino acid metabolism_Homo sapiens_hsa004600.58346913
104Type I diabetes mellitus_Homo sapiens_hsa049400.57312101
105Pyruvate metabolism_Homo sapiens_hsa006200.57035169
106Inositol phosphate metabolism_Homo sapiens_hsa005620.56116916
107Basal transcription factors_Homo sapiens_hsa030220.55918970
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54741432
109VEGF signaling pathway_Homo sapiens_hsa043700.54078386
1102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.53469871
111Proteasome_Homo sapiens_hsa030500.53425365
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.53140575
113Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.52419988
114Insulin signaling pathway_Homo sapiens_hsa049100.52127094
115Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51018718
116Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50935537
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50826887
118Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.50324995
119beta-Alanine metabolism_Homo sapiens_hsa004100.49912348
120Carbon metabolism_Homo sapiens_hsa012000.48829059
121Metabolic pathways_Homo sapiens_hsa011000.48754081
122Ribosome_Homo sapiens_hsa030100.48661382
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.48132433
124Homologous recombination_Homo sapiens_hsa034400.47548109
125DNA replication_Homo sapiens_hsa030300.46676716
126Dilated cardiomyopathy_Homo sapiens_hsa054140.46246459
127Mismatch repair_Homo sapiens_hsa034300.46104701
128Maturity onset diabetes of the young_Homo sapiens_hsa049500.46074322
129Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.45926128
130Basal cell carcinoma_Homo sapiens_hsa052170.45657816
131Endocytosis_Homo sapiens_hsa041440.44351758
132Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44231627
133Purine metabolism_Homo sapiens_hsa002300.43670890
134Renal cell carcinoma_Homo sapiens_hsa052110.43333826
135Ras signaling pathway_Homo sapiens_hsa040140.42915098
136Bile secretion_Homo sapiens_hsa049760.40948658
137mRNA surveillance pathway_Homo sapiens_hsa030150.38830224
138Rap1 signaling pathway_Homo sapiens_hsa040150.37933390
139Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37692072
140Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.35761689
141Wnt signaling pathway_Homo sapiens_hsa043100.35683900
142Prion diseases_Homo sapiens_hsa050200.34089329
143Sphingolipid signaling pathway_Homo sapiens_hsa040710.33772518
144SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33288347
145Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29500484
146Ovarian steroidogenesis_Homo sapiens_hsa049130.26251712
147Colorectal cancer_Homo sapiens_hsa052100.26079232
148Central carbon metabolism in cancer_Homo sapiens_hsa052300.25746270
149AMPK signaling pathway_Homo sapiens_hsa041520.25026247
150FoxO signaling pathway_Homo sapiens_hsa040680.24637420
151Bladder cancer_Homo sapiens_hsa052190.23695084
152Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.21795248

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