CCDC94

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.45329124
2ribosomal small subunit assembly (GO:0000028)4.56308623
3DNA strand elongation involved in DNA replication (GO:0006271)4.55508045
4telomere maintenance via semi-conservative replication (GO:0032201)4.38820655
5DNA strand elongation (GO:0022616)4.32417005
6formation of translation preinitiation complex (GO:0001731)4.27102474
7DNA replication initiation (GO:0006270)3.97537242
8DNA unwinding involved in DNA replication (GO:0006268)3.90773336
9viral transcription (GO:0019083)3.90224119
10nucleobase biosynthetic process (GO:0046112)3.85873163
11maturation of SSU-rRNA (GO:0030490)3.80848538
12ribosome biogenesis (GO:0042254)3.80766125
13translational termination (GO:0006415)3.80554879
14telomere maintenance via recombination (GO:0000722)3.79598143
15pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.61264208
16purine nucleobase biosynthetic process (GO:0009113)3.59625563
17protein localization to kinetochore (GO:0034501)3.56348602
18IMP biosynthetic process (GO:0006188)3.56028015
19translational elongation (GO:0006414)3.55367765
20ribonucleoprotein complex biogenesis (GO:0022613)3.54495943
21translational initiation (GO:0006413)3.48052146
22protein maturation by protein folding (GO:0022417)3.47670376
23ribosomal small subunit biogenesis (GO:0042274)3.43608998
24peptidyl-arginine omega-N-methylation (GO:0035247)3.43331608
25mitotic recombination (GO:0006312)3.42588234
26deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.38786796
27telomere maintenance via telomere lengthening (GO:0010833)3.37430561
28ribosome assembly (GO:0042255)3.34954638
29rRNA modification (GO:0000154)3.33800438
30IMP metabolic process (GO:0046040)3.32210466
31pseudouridine synthesis (GO:0001522)3.31719306
32base-excision repair, AP site formation (GO:0006285)3.30864883
33DNA replication checkpoint (GO:0000076)3.27542525
34negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.25225107
35nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.25114705
36ribosomal large subunit biogenesis (GO:0042273)3.23193260
37rRNA processing (GO:0006364)3.22524793
38folic acid-containing compound biosynthetic process (GO:0009396)3.22132693
39nucleotide-excision repair, DNA gap filling (GO:0006297)3.18193741
40regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.17772650
41negative regulation of interleukin-12 production (GO:0032695)3.15966911
42response to peptidoglycan (GO:0032494)3.15724883
43SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.15638836
44modulation by virus of host process (GO:0019054)3.13604497
45rRNA metabolic process (GO:0016072)3.09358888
46positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.09034687
47pyrimidine nucleotide catabolic process (GO:0006244)3.06947411
48cellular response to arsenic-containing substance (GO:0071243)3.05895315
49protein localization to chromosome, centromeric region (GO:0071459)3.05056919
50proteasome assembly (GO:0043248)3.05026246
51spliceosomal snRNP assembly (GO:0000387)3.04675033
52mitotic nuclear envelope disassembly (GO:0007077)3.04514189
53protein targeting to ER (GO:0045047)3.03796463
54cotranslational protein targeting to membrane (GO:0006613)3.03321979
55viral life cycle (GO:0019058)3.03126127
56modulation by symbiont of host cellular process (GO:0044068)3.01832950
573-UTR-mediated mRNA stabilization (GO:0070935)3.01393696
58folic acid metabolic process (GO:0046655)3.00175364
59pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.00022197
60somatic diversification of immune receptors via somatic mutation (GO:0002566)2.98285992
61somatic hypermutation of immunoglobulin genes (GO:0016446)2.98285992
62deoxyribonucleotide catabolic process (GO:0009264)2.94532271
63histone arginine methylation (GO:0034969)2.93485906
64cellular protein complex disassembly (GO:0043624)2.91582088
65CENP-A containing nucleosome assembly (GO:0034080)2.90771708
66protein localization to endoplasmic reticulum (GO:0070972)2.87469825
67mitotic metaphase plate congression (GO:0007080)2.87116524
68establishment of protein localization to endoplasmic reticulum (GO:0072599)2.85826780
69negative regulation of B cell apoptotic process (GO:0002903)2.85302171
70DNA replication-dependent nucleosome organization (GO:0034723)2.85138490
71DNA replication-dependent nucleosome assembly (GO:0006335)2.85138490
72negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.85111962
73nuclear envelope reassembly (GO:0031468)2.85051079
74mitotic nuclear envelope reassembly (GO:0007084)2.85051079
75purine deoxyribonucleotide catabolic process (GO:0009155)2.80785004
76immunoglobulin mediated immune response (GO:0016064)2.80382475
77chromatin remodeling at centromere (GO:0031055)2.79703149
78positive regulation of B cell differentiation (GO:0045579)2.78763316
79deoxyribose phosphate catabolic process (GO:0046386)2.78365982
80negative regulation of erythrocyte differentiation (GO:0045647)2.77912089
81regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.77486018
82anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.77139375
83DNA replication-independent nucleosome assembly (GO:0006336)2.76834424
84DNA replication-independent nucleosome organization (GO:0034724)2.76834424
85purine nucleotide salvage (GO:0032261)2.76720457
86positive regulation of release of cytochrome c from mitochondria (GO:0090200)2.76360550
87GDP-mannose metabolic process (GO:0019673)2.75675712
88regulation of type I interferon-mediated signaling pathway (GO:0060338)2.75588937
89membrane disassembly (GO:0030397)2.75573738
90nuclear envelope disassembly (GO:0051081)2.75573738
91purine-containing compound salvage (GO:0043101)2.75273424
92iron-sulfur cluster assembly (GO:0016226)2.75182232
93metallo-sulfur cluster assembly (GO:0031163)2.75182232
94cellular response to virus (GO:0098586)2.75047988
95positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.74088039
96peptidyl-arginine methylation (GO:0018216)2.73500785
97peptidyl-arginine N-methylation (GO:0035246)2.73500785
98protein complex disassembly (GO:0043241)2.71494806
99L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.70709718
100negative regulation of myeloid cell apoptotic process (GO:0033033)2.70219719
101translation (GO:0006412)2.69390279
102nuclear-transcribed mRNA catabolic process (GO:0000956)2.69217094
103rRNA methylation (GO:0031167)2.68732999
104termination of RNA polymerase II transcription (GO:0006369)2.68473726
105nucleotide salvage (GO:0043173)2.68456509
106positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.68246638
107activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.67849175
108Arp2/3 complex-mediated actin nucleation (GO:0034314)2.67403043
109negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.66117219
110NIK/NF-kappaB signaling (GO:0038061)2.64759015
111pteridine-containing compound biosynthetic process (GO:0042559)2.63404358
112negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.62840015
113negative regulation of ligase activity (GO:0051352)2.62840015
114antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.62170416
115antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.62170416
116regulation of spindle organization (GO:0090224)2.62162209
117myeloid dendritic cell activation (GO:0001773)2.61855447
118cellular component biogenesis (GO:0044085)2.58241764
119myeloid dendritic cell differentiation (GO:0043011)2.57810354
120RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.57793795
121mRNA splicing, via spliceosome (GO:0000398)2.57793795
122macromolecular complex disassembly (GO:0032984)2.57198879
123mRNA cleavage (GO:0006379)2.57180863
124mRNA catabolic process (GO:0006402)2.57114309
125RNA splicing, via transesterification reactions (GO:0000375)2.56930680
126G1/S transition of mitotic cell cycle (GO:0000082)2.56617591
127cell cycle G1/S phase transition (GO:0044843)2.56617591
128response to muramyl dipeptide (GO:0032495)2.56407063
129rRNA transcription (GO:0009303)2.56336590
130establishment of viral latency (GO:0019043)2.56262956
131RNA catabolic process (GO:0006401)2.56240816
132transcription-coupled nucleotide-excision repair (GO:0006283)2.55881934
133base-excision repair (GO:0006284)2.55667867
134regulation of double-strand break repair via homologous recombination (GO:0010569)2.54317589
135regulation of superoxide anion generation (GO:0032928)2.54156041
136positive regulation of lymphocyte apoptotic process (GO:0070230)2.53738095
137neutrophil activation involved in immune response (GO:0002283)2.53715004
138amino sugar catabolic process (GO:0046348)2.53472289
139lipopolysaccharide-mediated signaling pathway (GO:0031663)2.53215733
140positive regulation of gamma-delta T cell activation (GO:0046645)2.52351514
141regulation of B cell apoptotic process (GO:0002902)2.52004855
142antigen processing and presentation of endogenous antigen (GO:0019883)2.51908252
143transcription from mitochondrial promoter (GO:0006390)2.51078087
144negative regulation of RNA splicing (GO:0033119)2.50670693
145positive regulation by symbiont of host defense response (GO:0052509)2.50271258
146modulation by symbiont of host defense response (GO:0052031)2.50271258
147modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.50271258
148modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.50271258
149positive regulation by organism of defense response of other organism involved in symbiotic interact2.50271258
150modulation by symbiont of host immune response (GO:0052553)2.50271258
151regulation of release of cytochrome c from mitochondria (GO:0090199)2.49870761
152translesion synthesis (GO:0019985)2.49727902
153negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.48076449
154mitotic G1 DNA damage checkpoint (GO:0031571)2.47542155
155mismatch repair (GO:0006298)2.47039955
156ncRNA processing (GO:0034470)2.46667704
157pentose-phosphate shunt (GO:0006098)2.46198690
158telomere organization (GO:0032200)2.45958065
159cellular response to type I interferon (GO:0071357)2.44825493
160type I interferon signaling pathway (GO:0060337)2.44825493
161ncRNA 3-end processing (GO:0043628)2.43530293
162regulation of interleukin-2 biosynthetic process (GO:0045076)2.41250182
163negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.40122200
164regulation of vitamin D biosynthetic process (GO:0060556)2.39710918
165regulation of defense response to virus by virus (GO:0050690)2.38793615
166response to type I interferon (GO:0034340)2.36485201
167negative regulation of type I interferon production (GO:0032480)2.35916302
168negative regulation of DNA-templated transcription, elongation (GO:0032785)2.33971540
169T cell apoptotic process (GO:0070231)2.32950440
170spliceosomal tri-snRNP complex assembly (GO:0000244)2.32685371
171T cell migration (GO:0072678)2.32440308
172pyrimidine-containing compound salvage (GO:0008655)2.31029764
173pyrimidine nucleoside salvage (GO:0043097)2.31029764
174response to protozoan (GO:0001562)2.30237074
1752-deoxyribonucleotide metabolic process (GO:0009394)2.29681413
176negative regulation of innate immune response (GO:0045824)2.27065644
177pinocytosis (GO:0006907)2.26869637
178ubiquinone biosynthetic process (GO:0006744)2.26106596
179antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.26104300
180positive regulation of T cell apoptotic process (GO:0070234)2.24799710
181regulation of chemokine biosynthetic process (GO:0045073)2.23656337
182antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.23501417
183tolerance induction (GO:0002507)2.23245562
184deoxyribose phosphate biosynthetic process (GO:0046385)2.22473502
1852-deoxyribonucleotide biosynthetic process (GO:0009265)2.22473502
186positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.20004717

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.19965715
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.76190273
3* MYC_18555785_ChIP-Seq_MESCs_Mouse3.71650066
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.85609033
5MYC_18358816_ChIP-ChIP_MESCs_Mouse2.64757346
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.58524175
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.50407515
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.50239750
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.46242512
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.41247908
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.39879840
12* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.38273105
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.37780002
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.35149822
15MYC_22102868_ChIP-Seq_BL_Human2.35044168
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.33499785
17SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.20580065
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.15487011
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14743602
20BP1_19119308_ChIP-ChIP_Hs578T_Human2.06849454
21* VDR_23849224_ChIP-Seq_CD4+_Human2.05837097
22* XRN2_22483619_ChIP-Seq_HELA_Human2.05675854
23NELFA_20434984_ChIP-Seq_ESCs_Mouse1.96115915
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.93020736
25ELF1_17652178_ChIP-ChIP_JURKAT_Human1.89757794
26* FOXP3_21729870_ChIP-Seq_TREG_Human1.86608569
27VDR_21846776_ChIP-Seq_THP-1_Human1.84997013
28GABP_19822575_ChIP-Seq_HepG2_Human1.82037930
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.76876369
30* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.75567333
31DCP1A_22483619_ChIP-Seq_HELA_Human1.73616828
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.73348866
33* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.71143253
34LXR_22292898_ChIP-Seq_THP-1_Human1.69375055
35IRF8_22096565_ChIP-ChIP_GC-B_Human1.66535830
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.65264816
37PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.62990459
38NOTCH1_21737748_ChIP-Seq_TLL_Human1.62050037
39NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61819844
40CIITA_25753668_ChIP-Seq_RAJI_Human1.60175328
41ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57991312
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57844204
43* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.57716140
44THAP11_20581084_ChIP-Seq_MESCs_Mouse1.54298569
45* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51536998
46IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.50644739
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50385907
48TTF2_22483619_ChIP-Seq_HELA_Human1.50200573
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.49657634
50KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.46994755
51POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46291566
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.45874582
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.45594823
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.44290767
55FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.44147519
56MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.44109614
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.43018074
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.41294233
59ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40157892
60* SRF_21415370_ChIP-Seq_HL-1_Mouse1.39726342
61ELF1_20517297_ChIP-Seq_JURKAT_Human1.38752618
62SPI1_23547873_ChIP-Seq_NB4_Human1.36438275
63TET1_21451524_ChIP-Seq_MESCs_Mouse1.36424900
64ERG_20887958_ChIP-Seq_HPC-7_Mouse1.35900708
65AR_21909140_ChIP-Seq_LNCAP_Human1.35696898
66KDM5A_27292631_Chip-Seq_BREAST_Human1.35636884
67SCL_19346495_ChIP-Seq_HPC-7_Human1.35564367
68RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.35146921
69* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.33062124
70KDM2B_26808549_Chip-Seq_DND41_Human1.32305465
71E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.31100068
72P68_20966046_ChIP-Seq_HELA_Human1.30433770
73* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28927085
74DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.26402723
75POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25640656
76TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23575297
77BCOR_27268052_Chip-Seq_Bcells_Human1.23153426
78KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22919677
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.22748426
80BCL6_27268052_Chip-Seq_Bcells_Human1.22486143
81BRD4_27068464_Chip-Seq_AML-cells_Mouse1.22037779
82SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.21060247
83CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.20482707
84PU.1_20513432_ChIP-Seq_Bcells_Mouse1.20192066
85ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17725684
86MYB_21317192_ChIP-Seq_ERMYB_Mouse1.17187470
87ELK1_19687146_ChIP-ChIP_HELA_Human1.16014353
88TFEB_21752829_ChIP-Seq_HELA_Human1.15783229
89YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14379881
90SA1_27219007_Chip-Seq_ERYTHROID_Human1.13744548
91RACK7_27058665_Chip-Seq_MCF-7_Human1.13727888
92MAF_26560356_Chip-Seq_TH1_Human1.12988369
93PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12709716
94* CTCF_26484167_Chip-Seq_Bcells_Mouse1.12348676
95KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12216448
96SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.11619164
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.11509071
98KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.11220666
99* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.10898575
100NCOR1_26117541_ChIP-Seq_K562_Human1.10627149
101NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10477958
102* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.10453870
103NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10330369
104SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.09499808
105UTX_26944678_Chip-Seq_JUKART_Human1.09150821
106RUNX1_22412390_ChIP-Seq_EML_Mouse1.06530868
107BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.05870823
108E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.04704800
109E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01788337
110MYB_26560356_Chip-Seq_TH1_Human0.99827072
111TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.99473252
112STAT4_19710469_ChIP-ChIP_TH1__Mouse0.99296480
113MAF_26560356_Chip-Seq_TH2_Human0.99039864
114VDR_24763502_ChIP-Seq_THP-1_Human0.99014665
115* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.98532904
116KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98429565
117MYB_26560356_Chip-Seq_TH2_Human0.98199579
118SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.97314564
119CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.96631594
120IRF8_21731497_ChIP-ChIP_J774_Mouse0.96455519
121CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.96115310
122CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.95631611
123* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95251966
124PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.94986346
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94169005
126TCF7_22412390_ChIP-Seq_EML_Mouse0.90628459
127ELK3_25401928_ChIP-Seq_HUVEC_Human0.90544611

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.36605082
2MP0003111_abnormal_nucleus_morphology3.39955135
3MP0002396_abnormal_hematopoietic_system3.23877868
4MP0004957_abnormal_blastocyst_morpholog3.19282379
5MP0010094_abnormal_chromosome_stability3.17671557
6MP0003077_abnormal_cell_cycle3.06845543
7MP0005451_abnormal_body_composition2.94426720
8MP0008058_abnormal_DNA_repair2.75895028
9MP0008057_abnormal_DNA_replication2.66818555
10MP0008260_abnormal_autophagy2.54448634
11MP0008007_abnormal_cellular_replicative2.46074930
12MP0003763_abnormal_thymus_physiology2.30633177
13MP0001835_abnormal_antigen_presentation2.30475292
14MP0005397_hematopoietic_system_phenotyp2.19356242
15MP0001545_abnormal_hematopoietic_system2.19356242
16MP0009333_abnormal_splenocyte_physiolog2.18140717
17MP0004808_abnormal_hematopoietic_stem2.13339231
18MP0000685_abnormal_immune_system2.03312266
19MP0000490_abnormal_crypts_of2.01269698
20MP0002398_abnormal_bone_marrow1.97867528
21MP0010352_gastrointestinal_tract_polyps1.87049525
22MP0001853_heart_inflammation1.85408213
23MP0001800_abnormal_humoral_immune1.80431236
24MP0003436_decreased_susceptibility_to1.80331174
25MP0000689_abnormal_spleen_morphology1.79965191
26MP0002722_abnormal_immune_system1.78897690
27MP0005671_abnormal_response_to1.76245979
28MP0005075_abnormal_melanosome_morpholog1.73581060
29MP0008932_abnormal_embryonic_tissue1.69223813
30MP0000350_abnormal_cell_proliferation1.68415874
31MP0009278_abnormal_bone_marrow1.66001719
32MP0003786_premature_aging1.64752640
33MP0001730_embryonic_growth_arrest1.64325085
34MP0009785_altered_susceptibility_to1.64284406
35MP0002019_abnormal_tumor_incidence1.62247036
36MP0002452_abnormal_antigen_presenting1.60484962
37MP0000703_abnormal_thymus_morphology1.59920965
38MP0006082_CNS_inflammation1.58523852
39MP0003191_abnormal_cellular_cholesterol1.57938533
40MP0000716_abnormal_immune_system1.57823704
41MP0005464_abnormal_platelet_physiology1.57105130
42MP0002420_abnormal_adaptive_immunity1.55824107
43MP0002429_abnormal_blood_cell1.55668009
44MP0001819_abnormal_immune_cell1.54092964
45MP0002723_abnormal_immune_serum1.52949858
46MP0005025_abnormal_response_to1.51885181
47MP0005000_abnormal_immune_tolerance1.49453250
48MP0001533_abnormal_skeleton_physiology1.48099825
49MP0010307_abnormal_tumor_latency1.43786011
50MP0000313_abnormal_cell_death1.41753299
51MP0009840_abnormal_foam_cell1.41118702
52MP0002405_respiratory_system_inflammati1.39385582
53MP0009764_decreased_sensitivity_to1.39006861
54MP0000465_gastrointestinal_hemorrhage1.36157644
55MP0003806_abnormal_nucleotide_metabolis1.34943893
56MP0003656_abnormal_erythrocyte_physiolo1.32696205
57MP0003075_altered_response_to1.31699842
58MP0001727_abnormal_embryo_implantation1.31402182
59MP0004185_abnormal_adipocyte_glucose1.27360325
60MP0002254_reproductive_system_inflammat1.25756056
61MP0001873_stomach_inflammation1.24783159
62MP0003300_gastrointestinal_ulcer1.23444533
63MP0006035_abnormal_mitochondrial_morpho1.22354287
64MP0000343_altered_response_to1.20930422
65MP0000604_amyloidosis1.20536992
66MP0010155_abnormal_intestine_physiology1.20490752
67MP0002080_prenatal_lethality1.18248429
68MP0002132_abnormal_respiratory_system1.17873093
69MP0002419_abnormal_innate_immunity1.17405034
70MP0001697_abnormal_embryo_size1.16951965
71MP0002163_abnormal_gland_morphology1.13964923
72MP0000858_altered_metastatic_potential1.13146050
73MP0002166_altered_tumor_susceptibility1.09565381
74MP0001790_abnormal_immune_system1.08563479
75MP0005387_immune_system_phenotype1.08563479
76MP0005380_embryogenesis_phenotype1.07867117
77MP0001672_abnormal_embryogenesis/_devel1.07867117
78MP0001348_abnormal_lacrimal_gland1.06514561
79MP0003186_abnormal_redox_activity1.04982622
80MP0003567_abnormal_fetal_cardiomyocyte1.04340890
81MP0003718_maternal_effect1.02070762
82MP0003221_abnormal_cardiomyocyte_apopto1.01232346
83MP0002148_abnormal_hypersensitivity_rea1.01230677
84MP0004947_skin_inflammation1.00733675
85MP0001845_abnormal_inflammatory_respons1.00448722
86MP0003984_embryonic_growth_retardation0.99555877
87MP0008877_abnormal_DNA_methylation0.97849933
88MP0002088_abnormal_embryonic_growth/wei0.96770881
89MP0003866_abnormal_defecation0.95504933
90MP0000358_abnormal_cell_content/0.94763801
91MP0002086_abnormal_extraembryonic_tissu0.92843266
92MP0005174_abnormal_tail_pigmentation0.91546013
93MP0002006_tumorigenesis0.91189088
94MP0003329_amyloid_beta_deposits0.91161925
95MP0005023_abnormal_wound_healing0.90348994
96MP0001542_abnormal_bone_strength0.89926222
97MP0003724_increased_susceptibility_to0.85893487
98MP0008469_abnormal_protein_level0.85810178
99MP0008995_early_reproductive_senescence0.85297069
100MP0006036_abnormal_mitochondrial_physio0.85259455
101MP0004510_myositis0.85140623
102MP0002877_abnormal_melanocyte_morpholog0.82954021
103MP0002095_abnormal_skin_pigmentation0.81616020
104MP0005666_abnormal_adipose_tissue0.79488251
105MP0003172_abnormal_lysosome_physiology0.79486635
106MP0002085_abnormal_embryonic_tissue0.79468128
107MP0005166_decreased_susceptibility_to0.79193299
108MP0002332_abnormal_exercise_endurance0.77908511
109MP0000598_abnormal_liver_morphology0.77368483
110MP0000477_abnormal_intestine_morphology0.77253826
111MP0005621_abnormal_cell_physiology0.77216274
112MP0009763_increased_sensitivity_to0.76472315
113MP0005310_abnormal_salivary_gland0.74907498
114MP0005076_abnormal_cell_differentiation0.74042276
115MP0005384_cellular_phenotype0.73027542
116MP0003448_altered_tumor_morphology0.72682629
117MP0005266_abnormal_metabolism0.72383270
118MP0003303_peritoneal_inflammation0.72323818
119MP0001764_abnormal_homeostasis0.72110236
120MP0003566_abnormal_cell_adhesion0.72021212
121MP0002084_abnormal_developmental_patter0.72000188
122MP0009765_abnormal_xenobiotic_induced0.71893708
123MP0003453_abnormal_keratinocyte_physiol0.71037577
124MP0001851_eye_inflammation0.70242757
125MP0002653_abnormal_ependyma_morphology0.70179362
126MP0005058_abnormal_lysosome_morphology0.69856453
127MP0004084_abnormal_cardiac_muscle0.69674558
128MP0002998_abnormal_bone_remodeling0.68681446
129MP0005319_abnormal_enzyme/_coenzyme0.68639535
130MP0000750_abnormal_muscle_regeneration0.66995404
131MP0000609_abnormal_liver_physiology0.66121722

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.17979517
2Abnormal number of erythroid precursors (HP:0012131)4.05332467
3Birth length less than 3rd percentile (HP:0003561)3.96978215
4Abnormality of liposaccharide metabolism (HP:0010968)3.81292991
5Abnormality of glycosphingolipid metabolism (HP:0004343)3.81292991
6Abnormality of glycolipid metabolism (HP:0010969)3.81292991
7Aplastic anemia (HP:0001915)3.66843795
8Thrombocytosis (HP:0001894)3.66460311
9Mediastinal lymphadenopathy (HP:0100721)3.61900581
10Eczematoid dermatitis (HP:0000976)3.28180477
11Progressive muscle weakness (HP:0003323)3.27014798
12Stomatitis (HP:0010280)3.20551305
13Selective tooth agenesis (HP:0001592)3.19068904
14IgM deficiency (HP:0002850)3.17883062
15Oral leukoplakia (HP:0002745)3.17396226
16Reticulocytopenia (HP:0001896)3.17319118
17Elevated erythrocyte sedimentation rate (HP:0003565)3.15692517
18Recurrent bacterial skin infections (HP:0005406)3.09227078
19Increased IgM level (HP:0003496)3.09115790
20Abnormality of macrophages (HP:0004311)3.08259690
21Increased cerebral lipofuscin (HP:0011813)3.05977294
22Microretrognathia (HP:0000308)2.99207606
23Loss of speech (HP:0002371)2.89845265
24Petechiae (HP:0000967)2.81478181
25Multiple enchondromatosis (HP:0005701)2.78067594
26Ependymoma (HP:0002888)2.77352920
27Nasal polyposis (HP:0100582)2.77146166
28Increased neuronal autofluorescent lipopigment (HP:0002074)2.73387791
29Recurrent gram-negative bacterial infections (HP:0005420)2.72515821
30Abnormality of the nasal mucosa (HP:0000433)2.66319652
31Degeneration of anterior horn cells (HP:0002398)2.66235511
32Abnormality of the anterior horn cell (HP:0006802)2.66235511
33Cholecystitis (HP:0001082)2.65704500
34Abnormal gallbladder physiology (HP:0012438)2.65704500
35Rough bone trabeculation (HP:0100670)2.65482822
36Lymphoma (HP:0002665)2.65280139
37Abnormality of T cell physiology (HP:0011840)2.63918827
38Obstructive lung disease (HP:0006536)2.62283033
39Chronic obstructive pulmonary disease (HP:0006510)2.62283033
40Breast hypoplasia (HP:0003187)2.61929389
41Increased serum ferritin (HP:0003281)2.59960603
42Medulloblastoma (HP:0002885)2.59908839
43Agnosia (HP:0010524)2.58305281
44Abnormality of T cells (HP:0002843)2.58270467
45Chronic otitis media (HP:0000389)2.58235475
46Recurrent viral infections (HP:0004429)2.58019223
47Pallor (HP:0000980)2.55306125
48Dysostosis multiplex (HP:0000943)2.53381944
49Hepatosplenomegaly (HP:0001433)2.52555327
50Cerebral hypomyelination (HP:0006808)2.50689075
51Basal cell carcinoma (HP:0002671)2.50058674
52Amaurosis fugax (HP:0100576)2.46243851
53Vertebral compression fractures (HP:0002953)2.45749172
54Macrocytic anemia (HP:0001972)2.45309634
55Recurrent bronchitis (HP:0002837)2.44999704
56Patellar aplasia (HP:0006443)2.44754791
57Aplasia/Hypoplasia of the sacrum (HP:0008517)2.43690324
58Poikiloderma (HP:0001029)2.43095643
59Pancytopenia (HP:0001876)2.39754630
60Carpal bone hypoplasia (HP:0001498)2.39580135
61Axonal loss (HP:0003447)2.39137295
62Microvesicular hepatic steatosis (HP:0001414)2.37753317
63Panhypogammaglobulinemia (HP:0003139)2.36636823
64Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.34253022
65Hypertensive crisis (HP:0100735)2.33698581
66Muscle fiber atrophy (HP:0100295)2.32734202
67Meningitis (HP:0001287)2.32543433
68Colon cancer (HP:0003003)2.32235993
69Abnormality of the prostate (HP:0008775)2.29137763
70Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.28744761
71Systemic lupus erythematosus (HP:0002725)2.28670925
72Premature graying of hair (HP:0002216)2.28080371
73Aplasia/Hypoplasia of the patella (HP:0006498)2.28076857
74Reduced antithrombin III activity (HP:0001976)2.27235765
75Colitis (HP:0002583)2.26652786
76Gastrointestinal inflammation (HP:0004386)2.26146447
77IgG deficiency (HP:0004315)2.26097131
78Gastrointestinal stroma tumor (HP:0100723)2.24349005
79Myelodysplasia (HP:0002863)2.24302973
80Urticaria (HP:0001025)2.23860844
81Abnormality of the heme biosynthetic pathway (HP:0010472)2.23640517
82Increased intramyocellular lipid droplets (HP:0012240)2.21702911
83Prolonged neonatal jaundice (HP:0006579)2.18642629
84Increased muscle lipid content (HP:0009058)2.18148486
85Orchitis (HP:0100796)2.16922248
86Type I transferrin isoform profile (HP:0003642)2.15764665
87Prolonged bleeding time (HP:0003010)2.15311177
88Abnormal delayed hypersensitivity skin test (HP:0002963)2.14400389
89Pustule (HP:0200039)2.14261788
90Upper motor neuron abnormality (HP:0002127)2.13892900
91Achilles tendon contracture (HP:0001771)2.12814698
92Neoplasm of the pancreas (HP:0002894)2.12417481
93Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.11247194
94Myositis (HP:0100614)2.10713081
95T lymphocytopenia (HP:0005403)2.10375093
96Acute lymphatic leukemia (HP:0006721)2.09697879
97Abnormality of cells of the lymphoid lineage (HP:0012140)2.09421071
98Broad distal phalanx of finger (HP:0009836)2.09125089
99Bone marrow hypocellularity (HP:0005528)2.08335472
100Abnormality of iron homeostasis (HP:0011031)2.07976219
101Abnormality of polysaccharide metabolism (HP:0011012)2.07700844
102Abnormality of glycosaminoglycan metabolism (HP:0004371)2.07700844
103Abnormality of mucopolysaccharide metabolism (HP:0011020)2.07700844
104Type 2 muscle fiber atrophy (HP:0003554)2.07426888
105Progressive neurologic deterioration (HP:0002344)2.07383673
106Abnormal platelet function (HP:0011869)2.06638372
107Impaired platelet aggregation (HP:0003540)2.06638372
108Lymphopenia (HP:0001888)2.05568507
109Encephalitis (HP:0002383)2.05098006
110Entropion (HP:0000621)2.04739276
111Gingivitis (HP:0000230)2.04495006
112Increased IgE level (HP:0003212)2.03297745
113Centrally nucleated skeletal muscle fibers (HP:0003687)2.03273557
114Recurrent fungal infections (HP:0002841)2.02745066
115Inflammation of the large intestine (HP:0002037)2.01559164
116Thoracic kyphosis (HP:0002942)2.01448839
117Purpura (HP:0000979)2.00491088
118Agammaglobulinemia (HP:0004432)1.98511485
119Recurrent skin infections (HP:0001581)1.97829145
120Abnormality of T cell number (HP:0011839)1.97564719
121Neuronal loss in central nervous system (HP:0002529)1.97106238
122Ragged-red muscle fibers (HP:0003200)1.95761628
123Retrobulbar optic neuritis (HP:0100654)1.95626708
124Optic neuritis (HP:0100653)1.95626708
125Hypergammaglobulinemia (HP:0010702)1.95146635
126Cerebellar dysplasia (HP:0007033)1.95117826
127Autoimmune hemolytic anemia (HP:0001890)1.95001829
128Granulocytopenia (HP:0001913)1.94045276
129Prostate neoplasm (HP:0100787)1.93617542
130Cellular immunodeficiency (HP:0005374)1.92893619
131Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.92732856
132Decreased activity of mitochondrial respiratory chain (HP:0008972)1.92732856
133Recurrent cutaneous fungal infections (HP:0011370)1.92663350
134Chronic mucocutaneous candidiasis (HP:0002728)1.92663350
135Autoimmune thrombocytopenia (HP:0001973)1.92624614
136Albinism (HP:0001022)1.92552986
137Hepatocellular necrosis (HP:0001404)1.92122238
138IgA deficiency (HP:0002720)1.91933719
139Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.91550398
140Abnormality of B cell number (HP:0010975)1.91520147
141B lymphocytopenia (HP:0010976)1.91520147
142CNS hypomyelination (HP:0003429)1.91446235
143Vasculitis (HP:0002633)1.89878467
144Peripheral hypomyelination (HP:0007182)1.89456441
145Combined immunodeficiency (HP:0005387)1.88894672
146Rhabdomyosarcoma (HP:0002859)1.88393346
147Trismus (HP:0000211)1.88372004
148Recurrent abscess formation (HP:0002722)1.87652691
149Pulmonary fibrosis (HP:0002206)1.86737024
150Progressive external ophthalmoplegia (HP:0000590)1.86558468
15111 pairs of ribs (HP:0000878)1.85156008
152Premature ovarian failure (HP:0008209)1.84626143
153Absent thumb (HP:0009777)1.84012424
154Opisthotonus (HP:0002179)1.83332202
155Epistaxis (HP:0000421)1.83206739
156Leukopenia (HP:0001882)1.83106681
157Poor head control (HP:0002421)1.82832709
158Cellulitis (HP:0100658)1.82576395
159Abnormal trabecular bone morphology (HP:0100671)1.78814612
160Chromosomal breakage induced by crosslinking agents (HP:0003221)1.77059264
161Abnormality of eosinophils (HP:0001879)1.75203306
162Chromsome breakage (HP:0040012)1.75137204
163Optic nerve coloboma (HP:0000588)1.74840669
164Prominent nose (HP:0000448)1.74336854
165Abnormality of the preputium (HP:0100587)1.74014245
166Abnormality of the ileum (HP:0001549)1.73707555
167Abnormal number of incisors (HP:0011064)1.72155561
168Squamous cell carcinoma (HP:0002860)1.70697060

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.73775927
2WEE13.61565407
3MAP4K13.07285258
4EIF2AK12.57416139
5MAP3K102.53453887
6PRPF4B2.51421556
7NME22.36540640
8TESK12.24199310
9PIK3CG2.23572614
10STK162.20552530
11FLT32.17498587
12SMG12.15479662
13VRK22.14990370
14KIT2.14171566
15TAOK22.12818295
16NEK22.09060528
17CDC71.95687328
18ICK1.89076884
19ARAF1.81344969
20TESK21.79273469
21DYRK31.78107985
22RPS6KA41.70730238
23EEF2K1.67667980
24EIF2AK31.65763561
25PIM21.65417204
26CDK71.61727006
27STK101.56202422
28ZAP701.44713277
29ACVR1B1.44085420
30PKN21.43994562
31PLK41.43710721
32KDR1.43182874
33MAP3K141.42316086
34RPS6KB21.40926818
35PLK11.39809158
36BRSK21.37040512
37JAK31.36580424
38BCKDK1.34146678
39CSF1R1.33748512
40TGFBR11.30624682
41TYK21.30204972
42TAOK11.28588992
43TSSK61.28310233
44ERN11.27597770
45CDK41.26895150
46NEK11.25736185
47ATR1.25657591
48BTK1.25108721
49RIPK41.25071019
50PAK41.22172989
51MAP2K31.21515614
52VRK11.19886985
53MAP3K111.18063410
54SRPK11.18050304
55PIM11.17654866
56CCNB11.16604609
57PASK1.12775730
58AURKB1.12553736
59LIMK11.09916782
60BLK1.09867781
61FES1.09239393
62BRAF1.09123150
63MAP3K81.07578980
64TBK11.06881771
65GRK71.06611640
66TEC1.04952247
67TTK1.04329848
68GRK61.03088287
69TXK1.02316038
70MATK1.00879628
71MKNK10.99022277
72TNK20.96890331
73IKBKB0.96578020
74IRAK30.93641760
75LRRK20.93068604
76TRIB30.92517023
77PBK0.90437086
78ABL20.90403819
79MAP3K30.85952928
80SCYL20.82655407
81CHEK20.82329824
82TGFBR20.81635584
83CDK120.80871900
84STK40.79772660
85IKBKE0.78308379
86CHUK0.77289600
87SYK0.77026972
88BRSK10.76875961
89CSNK1G30.76203181
90SIK30.75519185
91AURKA0.75275064
92IRAK40.74734767
93TAF10.69824118
94RPS6KA50.68296543
95EPHB10.66169019
96CHEK10.65719595
97MAPK110.64744105
98MARK30.63575785
99RPS6KC10.62697648
100RPS6KL10.62697648
101MAPKAPK30.62274438
102MAP2K20.61322192
103CDK80.59029583
104LYN0.58061906
105BMX0.57782465
106MAP3K10.57257649
107LCK0.57114922
108HCK0.55653343
109IRAK20.55523311
110CSNK1A1L0.55293136
111RPS6KA20.53381522
112DAPK30.52483634
113HIPK20.52361196
114PRKD20.51713546
115RAF10.51647828
116PAK10.51600081
117CDK20.51387211
118FGR0.51218307
119FGFR40.49644465
120SIK20.49279422
121CSNK2A10.46939988
122MOS0.46409012
123TLK10.45080363
124PDK20.44224208
125CSNK2A20.43823948
126PRKCI0.43110215
127RIPK10.42968537
128CDK60.42667180
129MKNK20.42024205
130TAOK30.41971191
131EPHA20.41438728
132ILK0.40845979
133MAP2K60.39999374
134ALK0.39846062
135AKT20.39840827
136ITK0.39572584
137DAPK10.39170753
138DYRK1B0.35921559
139ATM0.35056915
140RPS6KA60.34064876
141CSK0.33635224
142CDK190.33236848
143RPS6KA10.32590805

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.87350541
2Mismatch repair_Homo sapiens_hsa034304.01506305
3Ribosome_Homo sapiens_hsa030103.49156393
4Base excision repair_Homo sapiens_hsa034103.01677693
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.01283771
6Spliceosome_Homo sapiens_hsa030402.95892270
7Proteasome_Homo sapiens_hsa030502.85881547
8RNA polymerase_Homo sapiens_hsa030202.72290005
9RNA transport_Homo sapiens_hsa030132.49876453
10Homologous recombination_Homo sapiens_hsa034402.45773104
11Nucleotide excision repair_Homo sapiens_hsa034202.32988581
12Pyrimidine metabolism_Homo sapiens_hsa002402.30562630
13One carbon pool by folate_Homo sapiens_hsa006702.17073516
14Cell cycle_Homo sapiens_hsa041102.12092265
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.08547436
16Primary immunodeficiency_Homo sapiens_hsa053401.72262943
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65335233
18Fanconi anemia pathway_Homo sapiens_hsa034601.64417503
19Folate biosynthesis_Homo sapiens_hsa007901.62773443
20Graft-versus-host disease_Homo sapiens_hsa053321.54647444
21Autoimmune thyroid disease_Homo sapiens_hsa053201.52569007
22Pentose phosphate pathway_Homo sapiens_hsa000301.42569335
23RNA degradation_Homo sapiens_hsa030181.41239864
24p53 signaling pathway_Homo sapiens_hsa041151.39327648
25Sulfur relay system_Homo sapiens_hsa041221.33693730
26Lysosome_Homo sapiens_hsa041421.31553176
27Tuberculosis_Homo sapiens_hsa051521.31423351
28Antigen processing and presentation_Homo sapiens_hsa046121.31363145
29Herpes simplex infection_Homo sapiens_hsa051681.30942664
30Rheumatoid arthritis_Homo sapiens_hsa053231.26309201
31Epstein-Barr virus infection_Homo sapiens_hsa051691.22745370
32Salmonella infection_Homo sapiens_hsa051321.18932447
33Glycosaminoglycan degradation_Homo sapiens_hsa005311.17312006
34Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.15026543
35Basal transcription factors_Homo sapiens_hsa030221.13920736
36Measles_Homo sapiens_hsa051621.13161313
37mRNA surveillance pathway_Homo sapiens_hsa030151.10923274
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.10826914
39Purine metabolism_Homo sapiens_hsa002301.10721148
40Biosynthesis of amino acids_Homo sapiens_hsa012301.09122985
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.08517847
42Selenocompound metabolism_Homo sapiens_hsa004501.08493885
43Type I diabetes mellitus_Homo sapiens_hsa049401.08044888
44Malaria_Homo sapiens_hsa051441.07898114
45Staphylococcus aureus infection_Homo sapiens_hsa051501.06968931
46Non-homologous end-joining_Homo sapiens_hsa034501.06826727
47Pertussis_Homo sapiens_hsa051331.06276958
48Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.04265512
49Legionellosis_Homo sapiens_hsa051341.01456163
50Bladder cancer_Homo sapiens_hsa052191.00890335
51Hepatitis C_Homo sapiens_hsa051600.97236230
52Leishmaniasis_Homo sapiens_hsa051400.95014092
53Acute myeloid leukemia_Homo sapiens_hsa052210.92973594
54Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91641181
55NF-kappa B signaling pathway_Homo sapiens_hsa040640.90452016
56Parkinsons disease_Homo sapiens_hsa050120.88080859
57B cell receptor signaling pathway_Homo sapiens_hsa046620.87905583
58Viral carcinogenesis_Homo sapiens_hsa052030.85513770
59Vitamin B6 metabolism_Homo sapiens_hsa007500.84941063
60Fructose and mannose metabolism_Homo sapiens_hsa000510.84151608
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.83586304
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.81620801
63RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.81136552
64Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.80180193
65Apoptosis_Homo sapiens_hsa042100.77530340
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.75203772
67African trypanosomiasis_Homo sapiens_hsa051430.74509281
68HTLV-I infection_Homo sapiens_hsa051660.74341769
69Oxidative phosphorylation_Homo sapiens_hsa001900.72675998
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72271995
71Hematopoietic cell lineage_Homo sapiens_hsa046400.72246479
72Systemic lupus erythematosus_Homo sapiens_hsa053220.71371619
73Shigellosis_Homo sapiens_hsa051310.70763008
74Hepatitis B_Homo sapiens_hsa051610.70080441
75Small cell lung cancer_Homo sapiens_hsa052220.67491534
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65167877
772-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.64958736
78Phagosome_Homo sapiens_hsa041450.64315547
79Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61565896
80Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61405985
81Cyanoamino acid metabolism_Homo sapiens_hsa004600.61270789
82Prion diseases_Homo sapiens_hsa050200.60873402
83Influenza A_Homo sapiens_hsa051640.59711915
84Jak-STAT signaling pathway_Homo sapiens_hsa046300.59225243
85Chronic myeloid leukemia_Homo sapiens_hsa052200.59138758
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59048980
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.58119561
88Allograft rejection_Homo sapiens_hsa053300.57066652
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56562198
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55503444
91Galactose metabolism_Homo sapiens_hsa000520.55385030
92VEGF signaling pathway_Homo sapiens_hsa043700.55135733
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54706125
94Carbon metabolism_Homo sapiens_hsa012000.53726808
95Asthma_Homo sapiens_hsa053100.52408986
96Thyroid cancer_Homo sapiens_hsa052160.51285271
97Osteoclast differentiation_Homo sapiens_hsa043800.51116330
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49649815
99Huntingtons disease_Homo sapiens_hsa050160.49254253
100Toll-like receptor signaling pathway_Homo sapiens_hsa046200.49116926
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48858872
102Central carbon metabolism in cancer_Homo sapiens_hsa052300.47846532
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47166068
104Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46353812
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46211948
106T cell receptor signaling pathway_Homo sapiens_hsa046600.45471213
107N-Glycan biosynthesis_Homo sapiens_hsa005100.45441182
108Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.44508294
109Notch signaling pathway_Homo sapiens_hsa043300.44497437
110Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44173659
111NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40486098
112Colorectal cancer_Homo sapiens_hsa052100.40293067
113Other glycan degradation_Homo sapiens_hsa005110.39796893
114Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.37796423
115Toxoplasmosis_Homo sapiens_hsa051450.37619076
116HIF-1 signaling pathway_Homo sapiens_hsa040660.36402740
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34361579
118Caffeine metabolism_Homo sapiens_hsa002320.34179988
119Non-small cell lung cancer_Homo sapiens_hsa052230.32501590
120TNF signaling pathway_Homo sapiens_hsa046680.30910002
121Pancreatic cancer_Homo sapiens_hsa052120.30194763
122Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.29074572
123Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28598944
124Oocyte meiosis_Homo sapiens_hsa041140.28030715
125mTOR signaling pathway_Homo sapiens_hsa041500.26638607
126Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.26252963
127Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.24578979
128Glutathione metabolism_Homo sapiens_hsa004800.23949075
129Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22535198
130Viral myocarditis_Homo sapiens_hsa054160.20875082

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