CCDC96

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome reaction (GO:0007340)9.88005063
2plasma membrane fusion (GO:0045026)9.61069593
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.34045151
4cell-cell recognition (GO:0009988)8.93120334
5binding of sperm to zona pellucida (GO:0007339)8.89974562
6reproduction (GO:0000003)8.56935901
7spermatid development (GO:0007286)8.47179004
8piRNA metabolic process (GO:0034587)8.27241761
9regulation of cilium movement (GO:0003352)8.01402031
10male meiosis (GO:0007140)7.46780203
11synaptonemal complex organization (GO:0070193)7.02149757
12single fertilization (GO:0007338)6.98972923
13ventricular system development (GO:0021591)6.95392131
14primary alcohol catabolic process (GO:0034310)6.79121405
15sperm capacitation (GO:0048240)6.52978046
16synaptonemal complex assembly (GO:0007130)6.45173781
17negative regulation of inclusion body assembly (GO:0090084)6.27200441
18fertilization (GO:0009566)5.83956000
19vitamin transmembrane transport (GO:0035461)5.78076360
20spermatogenesis (GO:0007283)5.54509434
21axoneme assembly (GO:0035082)5.52607420
22male gamete generation (GO:0048232)5.52305228
23ethanol metabolic process (GO:0006067)5.41840074
24diterpenoid biosynthetic process (GO:0016102)5.37737485
25microtubule depolymerization (GO:0007019)5.34592725
26male meiosis I (GO:0007141)5.28279953
27negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)5.18308369
28regulation of inclusion body assembly (GO:0090083)5.16769559
29gamete generation (GO:0007276)5.12248281
30DNA methylation involved in gamete generation (GO:0043046)5.09250665
31organic cation transport (GO:0015695)4.99587034
32tolerance induction (GO:0002507)4.98514485
33microtubule severing (GO:0051013)4.95639111
34pyrimidine-containing compound transmembrane transport (GO:0072531)4.92813894
35response to xenobiotic stimulus (GO:0009410)4.89314600
36lung epithelium development (GO:0060428)4.88665722
37cellular process involved in reproduction in multicellular organism (GO:0022412)4.82242520
38germ cell development (GO:0007281)4.80591208
39regulation of microtubule-based movement (GO:0060632)4.78929797
40intraciliary transport (GO:0042073)4.74812296
41spermatid nucleus differentiation (GO:0007289)4.72504470
42one-carbon compound transport (GO:0019755)4.64306743
43calcium ion-dependent exocytosis (GO:0017156)4.61866200
44left/right pattern formation (GO:0060972)4.57538150
45establishment of apical/basal cell polarity (GO:0035089)4.46174839
46protein localization to cilium (GO:0061512)4.46110825
47cell recognition (GO:0008037)4.43583520
48chromosome organization involved in meiosis (GO:0070192)4.38489121
49meiotic nuclear division (GO:0007126)4.38300574
50glomerular epithelial cell development (GO:0072310)4.36478936
51negative regulation of T cell differentiation in thymus (GO:0033085)4.23254161
52meiosis I (GO:0007127)4.23033128
53regulation of interleukin-5 production (GO:0032674)4.21353173
54meiotic cell cycle (GO:0051321)4.19230983
55negative regulation of B cell mediated immunity (GO:0002713)4.12490033
56negative regulation of immunoglobulin mediated immune response (GO:0002890)4.12490033
57cilium organization (GO:0044782)4.09316699
58multicellular organismal reproductive process (GO:0048609)4.01950643
59ethanol oxidation (GO:0006069)4.01022475
60protein polyglutamylation (GO:0018095)3.98648599
61nucleoside diphosphate phosphorylation (GO:0006165)3.97714557
62establishment of monopolar cell polarity (GO:0061162)3.94986017
63establishment or maintenance of monopolar cell polarity (GO:0061339)3.94986017
64regulation of interleukin-13 production (GO:0032656)3.93311253
65microtubule-based movement (GO:0007018)3.92084918
66cilium assembly (GO:0042384)3.89662362
67terpenoid biosynthetic process (GO:0016114)3.84920148
68cilium morphogenesis (GO:0060271)3.82583910
69negative regulation of humoral immune response (GO:0002921)3.81620624
70regulation of germinal center formation (GO:0002634)3.79819754
71positive regulation of tolerance induction (GO:0002645)3.74647441
72left/right axis specification (GO:0070986)3.73206738
73seminiferous tubule development (GO:0072520)3.70512835
74retinoic acid metabolic process (GO:0042573)3.65170767
75GTP biosynthetic process (GO:0006183)3.62488611
76cellular component assembly involved in morphogenesis (GO:0010927)3.60358249
77centriole replication (GO:0007099)3.58770111
78cytoplasmic microtubule organization (GO:0031122)3.58304486
79centriole assembly (GO:0098534)3.50703109
80establishment of tissue polarity (GO:0007164)3.47629844
81establishment of planar polarity (GO:0001736)3.47629844
82monoubiquitinated protein deubiquitination (GO:0035520)3.39580445
83regulation of centriole replication (GO:0046599)3.32140095
84apical protein localization (GO:0045176)3.30037675
85chaperone-mediated protein complex assembly (GO:0051131)3.22195841
86UTP biosynthetic process (GO:0006228)3.20846706
87multicellular organismal development (GO:0007275)3.19200688
88regulation of autophagic vacuole assembly (GO:2000785)3.15500279
89regulation of microtubule depolymerization (GO:0031114)3.15297597
90genitalia morphogenesis (GO:0035112)3.15149883
91protein K11-linked deubiquitination (GO:0035871)3.12328526
92glycerol ether metabolic process (GO:0006662)3.11227507
93lateral ventricle development (GO:0021670)3.10243489
94gene silencing by RNA (GO:0031047)3.03093219
95retinol metabolic process (GO:0042572)3.01083845
96microtubule bundle formation (GO:0001578)3.01069697
97ear development (GO:0043583)2.99063381
98negative regulation of organelle assembly (GO:1902116)2.98284123
99positive regulation of smoothened signaling pathway (GO:0045880)2.96422733
100chromosome condensation (GO:0030261)2.95746481
101phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.93263125
102DNA packaging (GO:0006323)2.92978459
103amino-acid betaine transport (GO:0015838)2.91189561
104carnitine transport (GO:0015879)2.91189561
105microtubule polymerization or depolymerization (GO:0031109)2.90393221
106determination of left/right symmetry (GO:0007368)2.89960783
107UTP metabolic process (GO:0046051)2.89602647
108protein refolding (GO:0042026)2.88521919
109regulation of tolerance induction (GO:0002643)2.88039411
110carnitine transmembrane transport (GO:1902603)2.86768680
111primary alcohol metabolic process (GO:0034308)2.86422363
112ether metabolic process (GO:0018904)2.86190089
113regulation of meiosis I (GO:0060631)2.81910821
114microtubule-based process (GO:0007017)2.81379118
115O-glycan processing (GO:0016266)2.80683095
116dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.80246254
117exogenous drug catabolic process (GO:0042738)2.79008556
118regulation of spindle checkpoint (GO:0090231)2.76511656
119determination of bilateral symmetry (GO:0009855)2.76436317
120lateral sprouting from an epithelium (GO:0060601)2.76226062
121hydrogen peroxide biosynthetic process (GO:0050665)2.75339900
122multicellular organismal water homeostasis (GO:0050891)2.72199690
123regulation of vacuole organization (GO:0044088)2.71834417
124meiotic cell cycle process (GO:1903046)2.71601271
125specification of symmetry (GO:0009799)2.70460966
126single strand break repair (GO:0000012)2.69727055
127glutathione derivative biosynthetic process (GO:1901687)2.69504488
128glutathione derivative metabolic process (GO:1901685)2.69504488
129smoothened signaling pathway (GO:0007224)2.68804707
130negative regulation of microtubule depolymerization (GO:0007026)2.66985258
131sexual reproduction (GO:0019953)2.62692117
132nucleus organization (GO:0006997)2.61932198
133regulation of toll-like receptor 4 signaling pathway (GO:0034143)2.61297163
134alditol metabolic process (GO:0019400)2.61165113
135regulation of response to osmotic stress (GO:0047484)2.54489870
136regulation of cilium assembly (GO:1902017)2.53853866
137cell projection assembly (GO:0030031)2.53310661
138drug catabolic process (GO:0042737)2.52629071
139establishment or maintenance of bipolar cell polarity (GO:0061245)2.50586033
140establishment or maintenance of apical/basal cell polarity (GO:0035088)2.50586033
141glycolytic process (GO:0006096)2.43364968
142regulation of cytokine production involved in inflammatory response (GO:1900015)2.43210700
143organelle assembly (GO:0070925)2.42845717
144synapsis (GO:0007129)2.42422941
145retinal rod cell development (GO:0046548)2.42324759
146regulation of protein polyubiquitination (GO:1902914)2.41584875
147mitotic sister chromatid cohesion (GO:0007064)2.41188407
148hypotonic response (GO:0006971)2.38458906
149reactive oxygen species biosynthetic process (GO:1903409)2.38101734
150asymmetric protein localization (GO:0008105)2.35198271
151phosphatidylcholine biosynthetic process (GO:0006656)2.33713002
152regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.31762540
153progesterone metabolic process (GO:0042448)2.31755140
154phosphatidylethanolamine biosynthetic process (GO:0006646)2.31713867
155cilium or flagellum-dependent cell motility (GO:0001539)15.3586446
156fusion of sperm to egg plasma membrane (GO:0007342)12.6395271
157axonemal dynein complex assembly (GO:0070286)12.6044626
158sperm motility (GO:0030317)11.4010809
159epithelial cilium movement (GO:0003351)11.1586731
160cilium movement (GO:0003341)10.9129831
161cell wall macromolecule metabolic process (GO:0044036)10.8581226
162cell wall macromolecule catabolic process (GO:0016998)10.8581226
163motile cilium assembly (GO:0044458)10.6475069
164multicellular organism reproduction (GO:0032504)10.2671984
165acrosome assembly (GO:0001675)10.1062286
166sperm-egg recognition (GO:0035036)10.0229771

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.28782670
2EZH2_22144423_ChIP-Seq_EOC_Human4.63846330
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.53355480
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.51730120
5DROSHA_22980978_ChIP-Seq_HELA_Human3.08709116
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.99231490
7TRIM28_21343339_ChIP-Seq_HEK293_Human2.55856386
8FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.48642188
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.18888775
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.15951809
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.13236304
12GATA1_26923725_Chip-Seq_HPCs_Mouse2.11578828
13TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.11150640
14SMC4_20622854_ChIP-Seq_HELA_Human2.10747026
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.02268700
16ESR2_21235772_ChIP-Seq_MCF-7_Human2.01369806
17PCGF2_27294783_Chip-Seq_ESCs_Mouse1.99764437
18EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.94957940
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92044941
20ELF1_20517297_ChIP-Seq_JURKAT_Human1.87474614
21RUNX1_27514584_Chip-Seq_MCF-7_Human1.86403127
22VDR_22108803_ChIP-Seq_LS180_Human1.86272799
23* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.81967124
24CBX2_27304074_Chip-Seq_ESCs_Mouse1.81540181
25STAT1_20625510_ChIP-Seq_HELA_Human1.80635112
26ZNF274_21170338_ChIP-Seq_K562_Hela1.79773481
27KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.73241064
28WDR5_24793694_ChIP-Seq_LNCAP_Human1.73092647
29ELK4_26923725_Chip-Seq_MESODERM_Mouse1.72928867
30AHR_22903824_ChIP-Seq_MCF-7_Human1.72073479
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70058360
32TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.69762972
33CTCF_27219007_Chip-Seq_Bcells_Human1.67982550
34SOX2_27498859_Chip-Seq_STOMACH_Mouse1.64453966
35* TP63_22573176_ChIP-Seq_HFKS_Human1.61769268
36MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.58915271
37PCGF2_27294783_Chip-Seq_NPCs_Mouse1.58752996
38P68_20966046_ChIP-Seq_HELA_Human1.57219622
39LXR_22292898_ChIP-Seq_THP-1_Human1.56078974
40* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.55279390
41TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.54521009
42CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.53150638
43RACK7_27058665_Chip-Seq_MCF-7_Human1.52651958
44KAP1_22055183_ChIP-Seq_ESCs_Mouse1.51978284
45KLF5_25053715_ChIP-Seq_YYC3_Human1.51624833
46SUZ12_27294783_Chip-Seq_NPCs_Mouse1.51132751
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.50936155
48STAT6_21828071_ChIP-Seq_BEAS2B_Human1.50076973
49RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.49825345
50TP63_17297297_ChIP-ChIP_HaCaT_Human1.47919297
51ESR1_20079471_ChIP-ChIP_T-47D_Human1.46806041
52TAL1_26923725_Chip-Seq_HPCs_Mouse1.45415497
53ARNT_22903824_ChIP-Seq_MCF-7_Human1.44624174
54PHF8_20622854_ChIP-Seq_HELA_Human1.43280827
55GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.42282022
56TDRD3_21172665_ChIP-Seq_MCF-7_Human1.42215996
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.41531714
58TP63_23658742_ChIP-Seq_EP156T_Human1.40305778
59ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.39976018
60CTBP2_25329375_ChIP-Seq_LNCAP_Human1.39736952
61P63_26484246_Chip-Seq_KERATINOCYTES_Human1.39526250
62REST_21632747_ChIP-Seq_MESCs_Mouse1.39364465
63CBP_20019798_ChIP-Seq_JUKART_Human1.38404662
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.38404662
65FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.38127855
66POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.36974708
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36974708
68TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36215881
69KDM2B_26808549_Chip-Seq_REH_Human1.36073817
70* STAT1_17558387_ChIP-Seq_HELA_Human1.34307352
71SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34132227
72YY1_22570637_ChIP-Seq_MALME-3M_Human1.32532272
73* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.32523863
74KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31719921
75SOX2_22085726_ChIP-Seq_NPCs_Mouse1.31200397
76NANOG_18555785_Chip-Seq_ESCs_Mouse1.30874168
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.30564530
78* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.30092134
79EZH2_27294783_Chip-Seq_ESCs_Mouse1.29842687
80CREB1_26743006_Chip-Seq_LNCaP_Human1.27172429
81E2F1_20622854_ChIP-Seq_HELA_Human1.25882349
82GATA1_19941826_ChIP-Seq_K562_Human1.25798644
83CRX_20693478_ChIP-Seq_RETINA_Mouse1.25454421
84EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.22961453
85ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.22814912
86ESR1_21235772_ChIP-Seq_MCF-7_Human1.21924137
87RNF2_27304074_Chip-Seq_NSC_Mouse1.20726367
88* SMRT_27268052_Chip-Seq_Bcells_Human1.20613961
89CTCF_20526341_ChIP-Seq_ESCs_Human1.20464980
90GATA3_21867929_ChIP-Seq_CD8_Mouse1.19538599
91FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19276283
92* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19224773
93OCT4_18555785_Chip-Seq_ESCs_Mouse1.18896030
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.17282747
95LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.16816683
96GF1_26923725_Chip-Seq_HPCs_Mouse1.16297799
97P53_22387025_ChIP-Seq_ESCs_Mouse1.15983819
98ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.15783859
99ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15531227
100CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14493633
101EZH2_27294783_Chip-Seq_NPCs_Mouse1.14332408
102CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.13003825
103OCT4_21477851_ChIP-Seq_ESCs_Mouse1.12052387
104* BCOR_27268052_Chip-Seq_Bcells_Human1.11384588
105CMYC_18555785_Chip-Seq_ESCs_Mouse1.10211856
106FOXM1_26456572_ChIP-Seq_MCF-7_Human1.10031785
107AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.10026964
108TP53_18474530_ChIP-ChIP_U2OS_Human1.09932567
109ETV1_20927104_ChIP-Seq_GIST48_Human1.09287941
110RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08518015
111STAT3_18555785_Chip-Seq_ESCs_Mouse1.07755165
112P300_18555785_Chip-Seq_ESCs_Mouse1.07719415
113KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.07623197
114BCL6_27268052_Chip-Seq_Bcells_Human1.06659372
115SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05623082
116FOXA1_25552417_ChIP-Seq_VCAP_Human1.05610246
117PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.05352606
118ESRRB_18555785_Chip-Seq_ESCs_Mouse1.05290826
119CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05111519
120SOX9_26525672_Chip-Seq_HEART_Mouse1.04704103
121PIAS1_25552417_ChIP-Seq_VCAP_Human1.04572953
122SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04340484
123ER_23166858_ChIP-Seq_MCF-7_Human1.04134584
124MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.04092953
125NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03567201
126EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.03350784
127P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.03221728
128TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03200101
129CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.03034193
130CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02869117
131TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.02544647
132CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02140820
133SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.01956657
134TBL1_22424771_ChIP-Seq_293T_Human1.01444554
135GF1B_26923725_Chip-Seq_HPCs_Mouse1.01158167
136KLF4_18555785_Chip-Seq_ESCs_Mouse1.00854587
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00784406
138HNFA_21074721_ChIP-Seq_CACO-2_Human1.00514128
139NFYB_21822215_ChIP-Seq_K562_Human1.00496073
140SA1_27219007_Chip-Seq_ERYTHROID_Human1.00364517
141* SOX2_20726797_ChIP-Seq_SW620_Human1.00361353
142SOX2_21211035_ChIP-Seq_LN229_Human1.00287421
143RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99498551
144GATA3_21867929_ChIP-Seq_TH1_Mouse0.99428283
145MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.99301611
146P300_27268052_Chip-Seq_Bcells_Human0.98818318
147EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98707254
148RARG_19884340_ChIP-ChIP_MEFs_Mouse0.98597342
149PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.98072616
150TCF4_23295773_ChIP-Seq_U87_Human0.97957269
151SOX2_18555785_Chip-Seq_ESCs_Mouse0.97664129
152* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.97353595
153SMAD4_21741376_ChIP-Seq_EPCs_Human0.97293449
154E2F1_18555785_Chip-Seq_ESCs_Mouse0.96927970
155NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.96526806
156PCGF4_22325352_ChIP-Seq_293T-Rex_Human0.96043329
157SUZ12_27294783_Chip-Seq_ESCs_Mouse0.95674144
158PU1_27457419_Chip-Seq_LIVER_Mouse0.95339903
159SMAD4_21799915_ChIP-Seq_A2780_Human0.95280679
160* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94396155
161RAD21_21589869_ChIP-Seq_MESCs_Mouse0.94251110
162* P53_21459846_ChIP-Seq_SAOS-2_Human0.94210394
163FUS_26573619_Chip-Seq_HEK293_Human0.92856052
164PHF8_20622853_ChIP-Seq_HELA_Human0.92158592
165MYC_27129775_Chip-Seq_CORNEA_Mouse0.91338775
166TP53_22127205_ChIP-Seq_IMR90_Human0.90549423
167PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.90534143
168CTCF_18555785_Chip-Seq_ESCs_Mouse0.90024712
169ERG_21242973_ChIP-ChIP_JURKAT_Human0.89886468
170RBPJ_21746931_ChIP-Seq_IB4_Human0.89352034
171RUNX1_26923725_Chip-Seq_HPCs_Mouse0.88738527
172CTBP1_25329375_ChIP-Seq_LNCAP_Human0.88505136
173ZFX_18555785_Chip-Seq_ESCs_Mouse0.88338996
174FLI1_21867929_ChIP-Seq_CD8_Mouse0.88029961
175RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.87808849
176CBX2_22325352_ChIP-Seq_293T-Rex_Human0.87802261
177FOXO3_23340844_ChIP-Seq_DLD1_Human0.87073898
178RUNX1_27457419_Chip-Seq_LIVER_Mouse0.86762308
179EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.86291636
180TAF15_26573619_Chip-Seq_HEK293_Human0.86101831
181RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.85205618
182OCT4_20526341_ChIP-Seq_ESCs_Human0.84746059
183TET1_21490601_ChIP-Seq_MESCs_Mouse0.83999048
184TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.83750754
185SA1_27219007_Chip-Seq_Bcells_Human0.82778802
186GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.81217239
187CEBPB_22108803_ChIP-Seq_LS180_Human0.79936016
188* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.79903438
189KLF4_19829295_ChIP-Seq_ESCs_Human0.79897910
190KDM2B_26808549_Chip-Seq_SUP-B15_Human0.79850372
191BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human0.79784735

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok6.15963673
2MP0003698_abnormal_male_reproductive5.65673855
3MP0001929_abnormal_gametogenesis5.11759881
4MP0002653_abnormal_ependyma_morphology4.77192160
5MP0002132_abnormal_respiratory_system4.71020743
6MP0008877_abnormal_DNA_methylation4.27576589
7MP0009780_abnormal_chondrocyte_physiolo3.82140057
8MP0002210_abnormal_sex_determination3.51334810
9MP0002277_abnormal_respiratory_mucosa3.34313787
10MP0002161_abnormal_fertility/fecundity3.05708646
11MP0001145_abnormal_male_reproductive2.90258715
12MP0005623_abnormal_meninges_morphology2.81516928
13MP0000678_abnormal_parathyroid_gland2.58114746
14MP0000653_abnormal_sex_gland2.53823769
15MP0001984_abnormal_olfaction2.48138994
16MP0010030_abnormal_orbit_morphology2.16400246
17MP0005410_abnormal_fertilization13.9894101
18MP0002160_abnormal_reproductive_system1.98554282
19MP0004019_abnormal_vitamin_homeostasis1.98517663
20MP0002822_catalepsy1.97812245
21MP0009379_abnormal_foot_pigmentation1.95277986
22MP0002282_abnormal_trachea_morphology1.90837303
23MP0009046_muscle_twitch1.77163471
24MP0003136_yellow_coat_color1.56712164
25MP0005670_abnormal_white_adipose1.56440639
26MP0005377_hearing/vestibular/ear_phenot1.56181290
27MP0003878_abnormal_ear_physiology1.56181290
28MP0002909_abnormal_adrenal_gland1.55185501
29MP0000383_abnormal_hair_follicle1.54819544
30MP0002168_other_aberrant_phenotype1.50900954
31MP0005083_abnormal_biliary_tract1.46883412
32MP0010678_abnormal_skin_adnexa1.41034128
33MP0003656_abnormal_erythrocyte_physiolo1.39275355
34MP0005248_abnormal_Harderian_gland1.35310793
35MP0003646_muscle_fatigue1.30089983
36MP0003283_abnormal_digestive_organ1.26785391
37MP0003950_abnormal_plasma_membrane1.24026317
38MP0008004_abnormal_stomach_pH1.20010244
39MP0001485_abnormal_pinna_reflex1.17943823
40MP0010234_abnormal_vibrissa_follicle1.14280507
41MP0004233_abnormal_muscle_weight1.12942596
42MP0005647_abnormal_sex_gland1.07693455
43MP0002638_abnormal_pupillary_reflex1.06212787
44MP0008057_abnormal_DNA_replication1.03609727
45MP0005395_other_phenotype1.03450516
46MP0002102_abnormal_ear_morphology1.00196797
47MP0001502_abnormal_circadian_rhythm0.99079401
48MP0005551_abnormal_eye_electrophysiolog0.98947085
49MP0002896_abnormal_bone_mineralization0.98222758
50MP0003453_abnormal_keratinocyte_physiol0.97679772
51MP0002234_abnormal_pharynx_morphology0.97427493
52MP0005389_reproductive_system_phenotype0.95670236
53MP0004133_heterotaxia0.95403551
54MP0002928_abnormal_bile_duct0.94831503
55MP0005165_increased_susceptibility_to0.92738317
56MP0005423_abnormal_somatic_nervous0.91555363
57MP0008058_abnormal_DNA_repair0.90293307
58MP0004883_abnormal_blood_vessel0.89874671
59MP0001765_abnormal_ion_homeostasis0.88078510
60MP0005164_abnormal_response_to0.87415572
61MP0005310_abnormal_salivary_gland0.86947957
62MP0003303_peritoneal_inflammation0.86188132
63MP0005408_hypopigmentation0.84228395
64MP0001348_abnormal_lacrimal_gland0.83376413
65MP0008995_early_reproductive_senescence0.82795433
66MP0004270_analgesia0.82408004
67MP0001346_abnormal_lacrimal_gland0.81626591
68MP0000681_abnormal_thyroid_gland0.80363943
69MP0010155_abnormal_intestine_physiology0.80021920
70MP0002098_abnormal_vibrissa_morphology0.79485810
71MP0005253_abnormal_eye_physiology0.78937199
72MP0003115_abnormal_respiratory_system0.78038945
73MP0003011_delayed_dark_adaptation0.77780677
74MP0009250_abnormal_appendicular_skeleto0.72947264
75MP0002136_abnormal_kidney_physiology0.72356425
76MP0005409_darkened_coat_color0.72245125
77MP0004885_abnormal_endolymph0.71256893
78MP0000467_abnormal_esophagus_morphology0.69591146
79MP0005503_abnormal_tendon_morphology0.68110694
80MP0003075_altered_response_to0.67092484
81MP0009765_abnormal_xenobiotic_induced0.67065281
82MP0003861_abnormal_nervous_system0.63767597
83MP0009643_abnormal_urine_homeostasis0.63548304
84MP0001663_abnormal_digestive_system0.63053737
85MP0001944_abnormal_pancreas_morphology0.63041819
86MP0005391_vision/eye_phenotype0.62921405
87MP0001293_anophthalmia0.62109540
88MP0002735_abnormal_chemical_nociception0.60599954
89MP0003329_amyloid_beta_deposits0.60165625
90MP0000858_altered_metastatic_potential0.59725768
91MP0003806_abnormal_nucleotide_metabolis0.59011410
92MP0002152_abnormal_brain_morphology0.58565947
93MP0001970_abnormal_pain_threshold0.57541274
94MP0003938_abnormal_ear_development0.56176281
95MP0003633_abnormal_nervous_system0.56103645
96MP0003634_abnormal_glial_cell0.55778804
97MP0005394_taste/olfaction_phenotype0.54733168
98MP0005499_abnormal_olfactory_system0.54733168
99MP0003937_abnormal_limbs/digits/tail_de0.54707930
100MP0009053_abnormal_anal_canal0.53910078
101MP0000163_abnormal_cartilage_morphology0.52717309
102MP0001664_abnormal_digestion0.52577855
103MP0000049_abnormal_middle_ear0.51515669
104MP0003866_abnormal_defecation0.51330373
105MP0003942_abnormal_urinary_system0.51008411
106MP0004134_abnormal_chest_morphology0.50536173
107MP0008007_abnormal_cellular_replicative0.50404380
108MP0005195_abnormal_posterior_eye0.50234061
109MP0000778_abnormal_nervous_system0.49036057
110MP0005023_abnormal_wound_healing0.48993372
111MP0003699_abnormal_female_reproductive0.48372347
112MP0000465_gastrointestinal_hemorrhage0.48243770
113MP0001324_abnormal_eye_pigmentation0.47900765
114MP0010094_abnormal_chromosome_stability0.47737678
115MP0009115_abnormal_fat_cell0.46656414
116MP0001963_abnormal_hearing_physiology0.46446118
117MP0002752_abnormal_somatic_nervous0.45060581
118MP0001849_ear_inflammation0.44605340
119MP0000432_abnormal_head_morphology0.44496546
120MP0000534_abnormal_ureter_morphology0.43827787
121MP0002736_abnormal_nociception_after0.43149075
122MP0000026_abnormal_inner_ear0.41251716
123MP0000566_synostosis0.41124978
124MP0002116_abnormal_craniofacial_bone0.41043046
125MP0001299_abnormal_eye_distance/0.40380151
126MP0003631_nervous_system_phenotype0.39958669
127MP0002092_abnormal_eye_morphology0.38592791
128MP0005257_abnormal_intraocular_pressure0.38491618
129MP0000428_abnormal_craniofacial_morphol0.38270854
130MP0000631_abnormal_neuroendocrine_gland0.37698303
131MP0002233_abnormal_nose_morphology0.37331397
132MP0001440_abnormal_grooming_behavior0.37264789
133MP0001119_abnormal_female_reproductive0.36779642
134MP0005646_abnormal_pituitary_gland0.36454628
135MP0000358_abnormal_cell_content/0.36058278
136MP0002882_abnormal_neuron_morphology0.35753996
137MP0008789_abnormal_olfactory_epithelium0.34355447
138MP0002572_abnormal_emotion/affect_behav0.34161259
139MP0002084_abnormal_developmental_patter0.33655313
140MP0002249_abnormal_larynx_morphology0.33211956
141MP0005388_respiratory_system_phenotype0.33100096
142MP0002133_abnormal_respiratory_system0.33100096
143MP0001270_distended_abdomen0.32816638
144MP0002557_abnormal_social/conspecific_i0.32646877
145MP0002734_abnormal_mechanical_nocicepti0.32412726
146MP0002697_abnormal_eye_size0.32168728
147MP0001968_abnormal_touch/_nociception0.31397233
148MP0002109_abnormal_limb_morphology0.30603347
149MP0002229_neurodegeneration0.30288594
150MP0005636_abnormal_mineral_homeostasis0.29791789
151MP0003879_abnormal_hair_cell0.29707823
152MP0004043_abnormal_pH_regulation0.29337419
153MP0003936_abnormal_reproductive_system0.29149801
154MP0005167_abnormal_blood-brain_barrier0.27335591
155MP0004811_abnormal_neuron_physiology0.26699692
156MP0002269_muscular_atrophy0.25812906

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.50999055
2Abnormal respiratory epithelium morphology (HP:0012253)9.50999055
3Abnormal ciliary motility (HP:0012262)9.08656008
4Rhinitis (HP:0012384)8.81151325
5Chronic bronchitis (HP:0004469)7.30391635
6Nasal polyposis (HP:0100582)5.96366008
7Infertility (HP:0000789)5.44697784
8Bronchiectasis (HP:0002110)5.04889102
9Abnormality of the nasal mucosa (HP:0000433)4.82934524
10Nephronophthisis (HP:0000090)4.28355718
11Bronchitis (HP:0012387)4.24365377
12Male infertility (HP:0003251)3.51575408
13Recurrent sinusitis (HP:0011108)3.42083987
14Tubulointerstitial nephritis (HP:0001970)3.34089171
15Abnormality of the renal medulla (HP:0100957)3.30438430
16Recurrent otitis media (HP:0000403)3.25526728
17Atelectasis (HP:0100750)3.16210579
18Abnormality of midbrain morphology (HP:0002418)2.92242688
19Molar tooth sign on MRI (HP:0002419)2.92242688
20Chronic otitis media (HP:0000389)2.88076827
21Medial flaring of the eyebrow (HP:0010747)2.86303882
22Hyperactive renin-angiotensin system (HP:0000841)2.70950927
23Pancreatic fibrosis (HP:0100732)2.52140160
24Postaxial foot polydactyly (HP:0001830)2.42079395
25True hermaphroditism (HP:0010459)2.39298011
26Tubular atrophy (HP:0000092)2.36912860
27Chronic sinusitis (HP:0011109)2.33414858
28Tubulointerstitial abnormality (HP:0001969)2.31606465
29Fibular hypoplasia (HP:0003038)2.25555496
30Abnormal spermatogenesis (HP:0008669)2.21150985
31Recurrent bronchitis (HP:0002837)2.20347872
32Congenital hepatic fibrosis (HP:0002612)2.12603979
33Abnormality of dentin (HP:0010299)2.10715809
34Congenital primary aphakia (HP:0007707)2.09918080
35Gait imbalance (HP:0002141)2.06000273
36Bile duct proliferation (HP:0001408)2.04074568
37Abnormal biliary tract physiology (HP:0012439)2.04074568
38Stage 5 chronic kidney disease (HP:0003774)2.03385325
39Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.5268688
40Absent/shortened dynein arms (HP:0200106)11.6271838
41Dynein arm defect of respiratory motile cilia (HP:0012255)11.6271838
42Abnormal respiratory motile cilium physiology (HP:0012261)10.4805156
43Cystic liver disease (HP:0006706)1.96472664
44Abnormality of permanent molar morphology (HP:0011071)1.94391286
45Abnormality of the dental root (HP:0006486)1.94391286
46Taurodontia (HP:0000679)1.94391286
47Aplasia/Hypoplasia of the tongue (HP:0010295)1.88319981
48Abnormality of the dental pulp (HP:0006479)1.87833267
49Abnormality of the lower motor neuron (HP:0002366)1.87739327
50Median cleft lip (HP:0000161)1.87230310
51Impulsivity (HP:0100710)1.85936086
52Postaxial hand polydactyly (HP:0001162)1.85912273
53Abnormality of molar (HP:0011077)1.81211745
54Abnormality of molar morphology (HP:0011070)1.81211745
55Nephrogenic diabetes insipidus (HP:0009806)1.76523240
56Renal dysplasia (HP:0000110)1.75247992
57Short ribs (HP:0000773)1.74305945
58Oculomotor apraxia (HP:0000657)1.74201319
59Hyperkalemia (HP:0002153)1.74155438
60Gonadotropin excess (HP:0000837)1.73060665
61Supernumerary spleens (HP:0009799)1.71494767
62Hypoplasia of the capital femoral epiphysis (HP:0003090)1.69485823
63Aplasia/Hypoplasia of the lens (HP:0008063)1.68056886
64Occipital encephalocele (HP:0002085)1.67289821
65Azoospermia (HP:0000027)1.66194910
66Pancreatic cysts (HP:0001737)1.65946811
67Decreased circulating renin level (HP:0003351)1.65833513
68Microglossia (HP:0000171)1.63565045
69Facial cleft (HP:0002006)1.62627839
70Aplasia/Hypoplasia of the fibula (HP:0006492)1.58984514
71Genital tract atresia (HP:0001827)1.58615316
72Abnormal drinking behavior (HP:0030082)1.58350272
73Polydipsia (HP:0001959)1.58350272
74Tubulointerstitial fibrosis (HP:0005576)1.58100760
75Aplasia/Hypoplasia of the sacrum (HP:0008517)1.56192439
76Poor coordination (HP:0002370)1.55376850
77Abnormality of the distal phalanges of the toes (HP:0010182)1.54405175
78Vaginal atresia (HP:0000148)1.54165238
79Abnormality of renal excretion (HP:0011036)1.53651067
80Broad distal phalanx of finger (HP:0009836)1.52522975
81Amyotrophic lateral sclerosis (HP:0007354)1.52277315
82Renal salt wasting (HP:0000127)1.52128600
83Furrowed tongue (HP:0000221)1.51655639
84Absent epiphyses (HP:0010577)1.48593386
85Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.48593386
86Short femoral neck (HP:0100864)1.47584954
87Hand muscle atrophy (HP:0009130)1.46317193
88Decreased central vision (HP:0007663)1.45893781
89Abnormality of the renal cortex (HP:0011035)1.45767101
90Chronic hepatic failure (HP:0100626)1.45330133
91Heterotopia (HP:0002282)1.41457360
92Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.41042261
93J-shaped sella turcica (HP:0002680)1.38427087
94Aplasia/Hypoplasia of the spleen (HP:0010451)1.36853619
95Hemiparesis (HP:0001269)1.36788671
96Retinal dysplasia (HP:0007973)1.36488207
97Abnormality of chloride homeostasis (HP:0011422)1.35889549
98Nephropathy (HP:0000112)1.35704635
99Short thorax (HP:0010306)1.35470019
100Asplenia (HP:0001746)1.34834022
101Anencephaly (HP:0002323)1.33043140
102Fetal akinesia sequence (HP:0001989)1.31542819
103Sclerocornea (HP:0000647)1.31143666
104Preaxial hand polydactyly (HP:0001177)1.29943212
105Bell-shaped thorax (HP:0001591)1.29582905
106Aplasia of the musculature (HP:0100854)1.29397360
10711 pairs of ribs (HP:0000878)1.28646126
108Abnormality of renin-angiotensin system (HP:0000847)1.28238929
109Obstructive sleep apnea (HP:0002870)1.27553671
110Abnormal urine output (HP:0012590)1.26363240
111Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.25458572
112Abnormality of the frontal sinuses (HP:0002687)1.22478538
113Spastic tetraparesis (HP:0001285)1.21627741
114Absent frontal sinuses (HP:0002688)1.20938087
115Male pseudohermaphroditism (HP:0000037)1.20924999
116Bifid tongue (HP:0010297)1.19077547
117Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.18087391
118Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.17434183
119Hyperaldosteronism (HP:0000859)1.17219130
120Short nail (HP:0001799)1.16889283
121Flat acetabular roof (HP:0003180)1.16633712
122Abnormality of ocular smooth pursuit (HP:0000617)1.13522005
123Cone-rod dystrophy (HP:0000548)1.10717360
124Bifid scrotum (HP:0000048)1.10128395
125Distal upper limb amyotrophy (HP:0007149)1.10036408
126Upper limb amyotrophy (HP:0009129)1.10036408
127Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.08385553
128Glucose intolerance (HP:0000833)1.07463692
129Abnormality of abdominal situs (HP:0011620)1.05955353
130Abdominal situs inversus (HP:0003363)1.05955353
131Ventricular fibrillation (HP:0001663)1.03915938
132Spinal cord compression (HP:0002176)0.97375536

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.45977930
2PDK48.45977930
3PDK25.45449474
4TESK14.76687358
5EPHA24.64060316
6MST43.71152603
7PRKD33.54831208
8ICK3.41382135
9PNCK3.16440452
10SMG12.33526573
11WNK42.28187134
12MAP3K22.28070027
13PTK2B2.24810769
14MAPK152.21239830
15STK392.14196008
16SIK21.86175689
17TRIB31.65667131
18NEK21.55545476
19CSK1.40264812
20STK381.34886694
21LRRK21.34620946
22CAMK1G1.21861350
23TRPM71.20142868
24MST1R1.18118195
25ERN11.13858118
26STK31.11396365
27EPHB11.07509603
28DYRK1B1.03472187
29LMTK21.01233579
30WNK10.92725897
31PLK40.90748673
32STK38L0.89942680
33NME10.89534473
34PRKCI0.84381291
35HIPK20.84136667
36CDK190.81586547
37WEE10.79943607
38MAP3K70.79051767
39TYRO30.77845923
40TBK10.77311629
41PDK10.75691585
42CDC70.75532546
43DYRK30.73928219
44IRAK10.73826225
45CHEK20.71585077
46ARAF0.70238031
47NTRK20.67615992
48RPS6KA20.65447615
49PINK10.64580315
50MET0.62563100
51PASK0.59658546
52GRK60.59537576
53MAP2K40.56749244
54CDK120.55996000
55CCNB10.54602846
56YES10.53861141
57CHEK10.51695755
58PTK20.51510602
59TLK10.46851509
60GRK10.46545662
61PRKCG0.45960559
62PRKCD0.45878931
63PAK20.44743417
64MAP3K60.41788986
65PTK60.40884662
66CDK90.40517924
67TAOK10.40337620
68EPHB20.40153167
69TTK0.39860018
70RIPK10.39443315
71MAP3K40.38805504
72CAMK2G0.37481438
73PAK40.37397495
74CDC42BPA0.37070614
75MTOR0.36823579
76STK160.36618408
77WNK30.35803516
78PAK10.35140528
79EEF2K0.35039637
80MAP3K120.34404571
81RIPK40.34085950
82AKT20.33832323
83ATM0.32928250
84CAMK1D0.32561515
85ROCK20.32443588
86PRKAA20.32217233
87PRKD20.32099548
88BCR0.31253952
89PDPK10.31197465
90DYRK1A0.30660603
91ERBB20.30537341
92MARK10.30092863
93SGK10.29790363
94SIK10.29155084
95BLK0.28589668
96NEK60.28187208
97ABL20.27655142
98ATR0.26336928
99MAP2K20.26179790
100PLK10.25816492
101PRKAA10.25550216
102DMPK0.25460843
103LIMK10.25249518
104MAPKAPK30.24784911
105CAMKK10.24305803
106MAP3K30.24183370
107STK100.23584273
108ADRBK10.22015982
109STK40.22007371
110PAK60.20475304
111MAP3K90.19305544
112LATS20.18552140
113NEK90.18542757
114CSNK1D0.18405657
115MAP2K60.17477778
116SGK2230.17477122
117SGK4940.17477122
118ZAP700.17054981
119BRSK10.16889236
120PRKCA0.16451078
121LATS10.16187588
122MAPK100.16047330
123CAMK2A0.15717793
124AURKA0.15350978
125BRSK20.15289769
126MARK20.15096853
127PRKACA0.15046953
128PRKG10.14962335
129GSK3B0.14260957
130PBK0.14214765
131STK110.13947401
132CDK30.11466560
133PKN10.11255435
134CDK10.11202086
135ROCK10.10576096
136CDK150.09647724
137PRKCZ0.09163679
138TESK20.09061830
139PRKACG0.08826288
140CDK20.08722782
141PDGFRB0.08668961
142MAP2K70.07964611
143CSNK1E0.07466110
144CDK180.07417422
145CDK11A0.06819714
146RPS6KA10.06800966
147IRAK20.06459185
148RPS6KA30.06456842
149PRKDC0.06052514
150ERBB30.05773314
151PRKACB0.05591045
152MUSK0.05459095
153PLK20.05203035
154MARK30.05198272
155PRKG20.05042019
156CDK140.04912796
157RPS6KB10.04329929
158DDR20.04328150
159MAPK80.04324307
160STK240.04173133
161PRKCB0.03948329

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003605.25199726
2Fatty acid biosynthesis_Homo sapiens_hsa000614.35177849
3Vitamin B6 metabolism_Homo sapiens_hsa007504.14606577
4Histidine metabolism_Homo sapiens_hsa003404.07543280
5Tyrosine metabolism_Homo sapiens_hsa003504.00672999
6Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.33087053
7Pyruvate metabolism_Homo sapiens_hsa006203.08267381
8Basal transcription factors_Homo sapiens_hsa030222.84957972
9beta-Alanine metabolism_Homo sapiens_hsa004102.78069819
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.70967502
11Dorso-ventral axis formation_Homo sapiens_hsa043202.57316530
12Glucagon signaling pathway_Homo sapiens_hsa049222.34412697
13Propanoate metabolism_Homo sapiens_hsa006402.30278733
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.18533293
15Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.05051139
16Huntingtons disease_Homo sapiens_hsa050162.02603849
17Linoleic acid metabolism_Homo sapiens_hsa005912.00674442
18Carbohydrate digestion and absorption_Homo sapiens_hsa049731.99498025
19Caffeine metabolism_Homo sapiens_hsa002321.97915971
20Retinol metabolism_Homo sapiens_hsa008301.92911181
21Fanconi anemia pathway_Homo sapiens_hsa034601.90103379
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.89680047
23Oocyte meiosis_Homo sapiens_hsa041141.89161289
24Pentose phosphate pathway_Homo sapiens_hsa000301.76144869
25PPAR signaling pathway_Homo sapiens_hsa033201.64956145
26Glycerolipid metabolism_Homo sapiens_hsa005611.62452733
27Amphetamine addiction_Homo sapiens_hsa050311.57027265
28Selenocompound metabolism_Homo sapiens_hsa004501.52539668
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.50091794
30Renin secretion_Homo sapiens_hsa049241.39263194
31Mineral absorption_Homo sapiens_hsa049781.35965375
32Olfactory transduction_Homo sapiens_hsa047401.35535106
33Ether lipid metabolism_Homo sapiens_hsa005651.34905678
34Cardiac muscle contraction_Homo sapiens_hsa042601.32711133
35Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.31494258
36Glycerophospholipid metabolism_Homo sapiens_hsa005641.31195949
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.30199064
38Hedgehog signaling pathway_Homo sapiens_hsa043401.27859292
39Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.26737077
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.22214212
41Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.21471694
42Phototransduction_Homo sapiens_hsa047441.20956870
43Notch signaling pathway_Homo sapiens_hsa043301.15881517
44Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.14479347
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.13858664
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.09939025
47mRNA surveillance pathway_Homo sapiens_hsa030151.03144364
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01527150
49Cocaine addiction_Homo sapiens_hsa050300.98891877
50Purine metabolism_Homo sapiens_hsa002300.97184434
51Estrogen signaling pathway_Homo sapiens_hsa049150.96824972
52Fructose and mannose metabolism_Homo sapiens_hsa000510.96487353
53Gastric acid secretion_Homo sapiens_hsa049710.93824027
54Carbon metabolism_Homo sapiens_hsa012000.90859980
55Insulin secretion_Homo sapiens_hsa049110.90667821
56Long-term potentiation_Homo sapiens_hsa047200.90075799
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.86397068
58Circadian rhythm_Homo sapiens_hsa047100.85840404
59Lysosome_Homo sapiens_hsa041420.84803150
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84193740
61Glutathione metabolism_Homo sapiens_hsa004800.84103816
62Fatty acid metabolism_Homo sapiens_hsa012120.83654553
63Thyroid hormone synthesis_Homo sapiens_hsa049180.83591892
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81737596
65Salivary secretion_Homo sapiens_hsa049700.80877987
66Antigen processing and presentation_Homo sapiens_hsa046120.80515022
67Basal cell carcinoma_Homo sapiens_hsa052170.79553509
68Fatty acid degradation_Homo sapiens_hsa000710.76772213
69Calcium signaling pathway_Homo sapiens_hsa040200.76227688
70Bile secretion_Homo sapiens_hsa049760.74667521
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74539991
72RNA transport_Homo sapiens_hsa030130.74310977
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74252422
74Leukocyte transendothelial migration_Homo sapiens_hsa046700.73444784
75Circadian entrainment_Homo sapiens_hsa047130.71442932
76Choline metabolism in cancer_Homo sapiens_hsa052310.70941246
77Wnt signaling pathway_Homo sapiens_hsa043100.70650602
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68797790
79Hepatitis C_Homo sapiens_hsa051600.67863703
80Systemic lupus erythematosus_Homo sapiens_hsa053220.67481853
81Phagosome_Homo sapiens_hsa041450.66195283
82cAMP signaling pathway_Homo sapiens_hsa040240.65186650
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65038824
84Taste transduction_Homo sapiens_hsa047420.64732803
85Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64570621
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64243898
87Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.63130564
88ABC transporters_Homo sapiens_hsa020100.62538946
89Collecting duct acid secretion_Homo sapiens_hsa049660.62011336
90Vibrio cholerae infection_Homo sapiens_hsa051100.61812765
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59254161
92Renin-angiotensin system_Homo sapiens_hsa046140.58639335
93Fat digestion and absorption_Homo sapiens_hsa049750.57959454
94Pancreatic secretion_Homo sapiens_hsa049720.57457618
95Inositol phosphate metabolism_Homo sapiens_hsa005620.56417706
96Sphingolipid metabolism_Homo sapiens_hsa006000.55302153
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51942650
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51247978
99Protein digestion and absorption_Homo sapiens_hsa049740.50925807
100Adherens junction_Homo sapiens_hsa045200.49950909
101Adipocytokine signaling pathway_Homo sapiens_hsa049200.49780715
102Type II diabetes mellitus_Homo sapiens_hsa049300.49651869
103Glutamatergic synapse_Homo sapiens_hsa047240.49023354
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.48085938
105Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47879645
106Prostate cancer_Homo sapiens_hsa052150.47848571
107Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47806538
108Amoebiasis_Homo sapiens_hsa051460.47517574
109Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46372896
110Chemical carcinogenesis_Homo sapiens_hsa052040.45522306
111Synaptic vesicle cycle_Homo sapiens_hsa047210.43653615
112Biosynthesis of amino acids_Homo sapiens_hsa012300.42729990
113Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42489541
114Tight junction_Homo sapiens_hsa045300.41946949
115Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41557324
116Type I diabetes mellitus_Homo sapiens_hsa049400.41044293
117Alcoholism_Homo sapiens_hsa050340.40877030
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.40332923
119Peroxisome_Homo sapiens_hsa041460.39813449
120Arachidonic acid metabolism_Homo sapiens_hsa005900.39784400
121Endocytosis_Homo sapiens_hsa041440.39580728
122Serotonergic synapse_Homo sapiens_hsa047260.38802065
123Hematopoietic cell lineage_Homo sapiens_hsa046400.35438106
124Primary bile acid biosynthesis_Homo sapiens_hsa001200.35238128
125Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.34646286
126Hippo signaling pathway_Homo sapiens_hsa043900.34283540
127Nicotine addiction_Homo sapiens_hsa050330.32742347
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32031398
129Prion diseases_Homo sapiens_hsa050200.30661400
130Dopaminergic synapse_Homo sapiens_hsa047280.30236452
131Starch and sucrose metabolism_Homo sapiens_hsa005000.30007652
132Vascular smooth muscle contraction_Homo sapiens_hsa042700.29102121
133Insulin resistance_Homo sapiens_hsa049310.28736642
134Folate biosynthesis_Homo sapiens_hsa007900.28550052
135Metabolic pathways_Homo sapiens_hsa011000.27977321
136Homologous recombination_Homo sapiens_hsa034400.27562993
137Ovarian steroidogenesis_Homo sapiens_hsa049130.27346794
138Melanogenesis_Homo sapiens_hsa049160.27027633
139Cell cycle_Homo sapiens_hsa041100.26843030
140Axon guidance_Homo sapiens_hsa043600.26657306
141AMPK signaling pathway_Homo sapiens_hsa041520.26528395
142Gap junction_Homo sapiens_hsa045400.25452117
143Nitrogen metabolism_Homo sapiens_hsa009100.25328468
144N-Glycan biosynthesis_Homo sapiens_hsa005100.24046161
145Regulation of autophagy_Homo sapiens_hsa041400.22475653
146Oxytocin signaling pathway_Homo sapiens_hsa049210.22045416
147Steroid biosynthesis_Homo sapiens_hsa001000.21646066
148Arginine and proline metabolism_Homo sapiens_hsa003300.21431701
149Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.21248653
150Staphylococcus aureus infection_Homo sapiens_hsa051500.20887007
151Endometrial cancer_Homo sapiens_hsa052130.20011559
152Drug metabolism - other enzymes_Homo sapiens_hsa009830.19990273
153Complement and coagulation cascades_Homo sapiens_hsa046100.19791112
154Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.18317705
155Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.16869619
156Dilated cardiomyopathy_Homo sapiens_hsa054140.14464255
157Jak-STAT signaling pathway_Homo sapiens_hsa046300.14201792
158Rheumatoid arthritis_Homo sapiens_hsa053230.12440267

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