CCDC97

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of histone deacetylation (GO:0031065)5.34982785
2positive regulation of gamma-delta T cell activation (GO:0046645)4.91759328
3regulation of gamma-delta T cell differentiation (GO:0045586)4.81635970
4negative regulation of erythrocyte differentiation (GO:0045647)4.58109382
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.54402776
6positive regulation of type I interferon-mediated signaling pathway (GO:0060340)4.46251288
7antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.42284410
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.42284410
9modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.38387157
10positive regulation by organism of defense response of other organism involved in symbiotic interact4.38387157
11modulation by symbiont of host immune response (GO:0052553)4.38387157
12positive regulation by symbiont of host defense response (GO:0052509)4.38387157
13modulation by symbiont of host defense response (GO:0052031)4.38387157
14modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.38387157
15regulation of gamma-delta T cell activation (GO:0046643)4.27997381
16positive regulation of protein deacetylation (GO:0090312)4.08578474
17antigen processing and presentation of endogenous antigen (GO:0019883)3.98045538
18detection of bacterium (GO:0016045)3.91878299
19detection of other organism (GO:0098543)3.87673080
20negative regulation of cell size (GO:0045792)3.87463258
21response to peptidoglycan (GO:0032494)3.86748531
22modulation by virus of host process (GO:0019054)3.79686837
23positive thymic T cell selection (GO:0045059)3.77886483
24response to muramyl dipeptide (GO:0032495)3.73440421
25neutrophil activation involved in immune response (GO:0002283)3.69477971
26macrophage activation involved in immune response (GO:0002281)3.59654254
27positive regulation of B cell differentiation (GO:0045579)3.58854824
28megakaryocyte development (GO:0035855)3.55330338
29leukocyte aggregation (GO:0070486)3.53999750
30modulation by symbiont of host cellular process (GO:0044068)3.52518480
31sarcomere organization (GO:0045214)3.52124581
32intracellular estrogen receptor signaling pathway (GO:0030520)3.48405186
33regulation of erythrocyte differentiation (GO:0045646)3.40745762
34natural killer cell differentiation (GO:0001779)3.37557915
35immunoglobulin mediated immune response (GO:0016064)3.36227624
36regulation of interleukin-12 biosynthetic process (GO:0045075)3.33108392
37tolerance induction (GO:0002507)3.29963144
38germinal center formation (GO:0002467)3.28115771
39regulation of interferon-beta biosynthetic process (GO:0045357)3.26754258
40response to type I interferon (GO:0034340)3.22897697
41type I interferon signaling pathway (GO:0060337)3.22591910
42cellular response to type I interferon (GO:0071357)3.22591910
43platelet formation (GO:0030220)3.17010181
44cardiac myofibril assembly (GO:0055003)3.16870000
45thymic T cell selection (GO:0045061)3.16429486
46antigen processing and presentation via MHC class Ib (GO:0002475)3.15859389
47regulation of T-helper 2 cell differentiation (GO:0045628)3.15453875
48negative regulation of stress fiber assembly (GO:0051497)3.15053833
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.14812139
50negative regulation of cell killing (GO:0031342)3.14812139
51positive regulation of gene expression, epigenetic (GO:0045815)3.14601849
52detection of external biotic stimulus (GO:0098581)3.09344890
533-UTR-mediated mRNA stabilization (GO:0070935)3.08325318
54cellular response to virus (GO:0098586)3.04260239
55positive regulation of Cdc42 GTPase activity (GO:0043089)3.02092303
56regulation of NFAT protein import into nucleus (GO:0051532)3.01935163
57response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.01054598
58response to host immune response (GO:0052572)3.01054598
59positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.01000076
60negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.99773995
61response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.98926796
62response to host (GO:0075136)2.98926796
63response to host defenses (GO:0052200)2.98926796
64nucleosome disassembly (GO:0006337)2.97384978
65protein-DNA complex disassembly (GO:0032986)2.97384978
66B cell receptor signaling pathway (GO:0050853)2.97094488
67maternal placenta development (GO:0001893)2.96114874
68apoptotic process involved in morphogenesis (GO:0060561)2.96002709
69regulation of leukocyte degranulation (GO:0043300)2.95837915
70cellular response to zinc ion (GO:0071294)2.94308218
71negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.94077152
72regulation of B cell differentiation (GO:0045577)2.91347604
73negative regulation of leukocyte mediated immunity (GO:0002704)2.91290420
74embryonic hemopoiesis (GO:0035162)2.91248612
75pre-miRNA processing (GO:0031054)2.90091891
76regulation of B cell receptor signaling pathway (GO:0050855)2.89963836
77negative regulation of lymphocyte mediated immunity (GO:0002707)2.89827687
78regulation of myeloid leukocyte mediated immunity (GO:0002886)2.88529341
79negative regulation of viral release from host cell (GO:1902187)2.88434343
80negative regulation of histone methylation (GO:0031061)2.86512498
81positive regulation of lamellipodium organization (GO:1902745)2.86077835
82negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.85817807
83mitotic G1 DNA damage checkpoint (GO:0031571)2.83886518
84negative regulation of toll-like receptor signaling pathway (GO:0034122)2.82645081
85regulation of translational fidelity (GO:0006450)2.79432067
86regulation of mast cell degranulation (GO:0043304)2.78208078
87negative regulation of phagocytosis (GO:0050765)2.78066199
88myofibril assembly (GO:0030239)2.77396256
89neutrophil activation (GO:0042119)2.77076002
90mannose metabolic process (GO:0006013)2.76989451
91positive regulation of lamellipodium assembly (GO:0010592)2.76928002
92negative regulation of granulocyte differentiation (GO:0030853)2.76763225
93cell-substrate adherens junction assembly (GO:0007045)2.76060346
94focal adhesion assembly (GO:0048041)2.76060346
95regulation of histone deacetylation (GO:0031063)2.75918318
96NLS-bearing protein import into nucleus (GO:0006607)2.75807892
97negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.75535145
98trophectodermal cell differentiation (GO:0001829)2.73628368
99negative regulation of innate immune response (GO:0045824)2.73446353
100negative thymic T cell selection (GO:0045060)2.73402069
101detection of biotic stimulus (GO:0009595)2.70778786
102negative regulation of potassium ion transmembrane transport (GO:1901380)2.70611169
103erythrocyte development (GO:0048821)2.69814466
104regulation of dendritic cell antigen processing and presentation (GO:0002604)2.69779604
105T cell selection (GO:0045058)2.69403129
106histone H3-K36 demethylation (GO:0070544)2.69392483
107negative regulation of nucleotide catabolic process (GO:0030812)2.69037838
108dosage compensation (GO:0007549)2.67823513
109positive regulation of blood vessel endothelial cell migration (GO:0043536)2.66954331
110T cell apoptotic process (GO:0070231)2.66865899
111response to interleukin-15 (GO:0070672)2.66405405
112regulation of integrin activation (GO:0033623)2.66187268
113negative regulation of type 2 immune response (GO:0002829)2.65397072
114granulocyte activation (GO:0036230)2.64984611
115negative T cell selection (GO:0043383)2.64963630
116retinoic acid receptor signaling pathway (GO:0048384)2.64561765
117positive T cell selection (GO:0043368)2.62240124
118plasma membrane repair (GO:0001778)2.62230785
119RNA stabilization (GO:0043489)2.61694857
120mRNA stabilization (GO:0048255)2.61694857
121histone H4-K16 acetylation (GO:0043984)2.60779587
122regulation of T cell tolerance induction (GO:0002664)2.59732022
123positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.56697494
124lipopolysaccharide-mediated signaling pathway (GO:0031663)2.56076412
125positive regulation of triglyceride biosynthetic process (GO:0010867)2.55341500
126respiratory burst (GO:0045730)2.53866712
127poly(A)+ mRNA export from nucleus (GO:0016973)2.52962415
128negative regulation of T cell mediated immunity (GO:0002710)2.52775011
129regulation of tolerance induction (GO:0002643)2.51549926
130NIK/NF-kappaB signaling (GO:0038061)2.51489084
131B cell homeostasis (GO:0001782)2.51221829
132detection of molecule of bacterial origin (GO:0032490)2.50774449
133mitotic G1/S transition checkpoint (GO:0044819)2.50578184
134regulation of type I interferon-mediated signaling pathway (GO:0060338)2.49914435
135cardiac muscle contraction (GO:0060048)2.49627218
136negative regulation of necroptotic process (GO:0060546)2.48947013
137positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.47756572
138JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.46963387
139regulation of chromatin binding (GO:0035561)2.44983656
140peptidyl-lysine dimethylation (GO:0018027)2.44474861
141regulation of cholesterol homeostasis (GO:2000188)2.44427221
142defense response to protozoan (GO:0042832)2.43264220
143negative regulation of interleukin-12 production (GO:0032695)2.43157723
144adherens junction assembly (GO:0034333)2.43155649
145regulation of necroptotic process (GO:0060544)2.42891177
146T cell migration (GO:0072678)2.42509382
147regulation of type 2 immune response (GO:0002828)2.42295629
148myeloid cell development (GO:0061515)2.41823139
149negative regulation of RNA splicing (GO:0033119)2.41416413
150mucosal-associated lymphoid tissue development (GO:0048537)2.41389017
151Peyers patch development (GO:0048541)2.41389017
152cell-substrate junction assembly (GO:0007044)2.41332029
153execution phase of apoptosis (GO:0097194)2.41190799
154regulation of protein deacetylation (GO:0090311)2.40966235
155positive regulation of type 2 immune response (GO:0002830)2.40483792
156positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.40335736
157myeloid cell activation involved in immune response (GO:0002275)2.40214696
158signal complex assembly (GO:0007172)2.39792305
159response to protozoan (GO:0001562)2.39444547
160sodium ion export (GO:0071436)2.39362153
161modulation by virus of host morphology or physiology (GO:0019048)2.39320886
162positive regulation of erythrocyte differentiation (GO:0045648)2.39223868
163negative regulation of gene expression, epigenetic (GO:0045814)2.37321740
164activation of JUN kinase activity (GO:0007257)2.36612237
165barbed-end actin filament capping (GO:0051016)2.35810385
166positive regulation of RNA splicing (GO:0033120)2.35063130
167stress fiber assembly (GO:0043149)2.32218205
168response to laminar fluid shear stress (GO:0034616)2.31730258

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* MYC_22102868_ChIP-Seq_BL_Human4.01882827
2* VDR_21846776_ChIP-Seq_THP-1_Human3.17518766
3EGR1_19374776_ChIP-ChIP_THP-1_Human2.71866211
4TCF7_22412390_ChIP-Seq_EML_Mouse2.64890529
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.62077333
6* KDM2B_26808549_Chip-Seq_DND41_Human2.52905264
7* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.51916039
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.36464636
9KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.36371839
10ELK3_25401928_ChIP-Seq_HUVEC_Human2.24721211
11SCL_19346495_ChIP-Seq_HPC-7_Human2.24060678
12KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.22475517
13TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.19566160
14LXR_22292898_ChIP-Seq_THP-1_Human2.16928016
15* MAF_26560356_Chip-Seq_TH1_Human2.16518223
16* UTX_26944678_Chip-Seq_JUKART_Human2.07856123
17TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.06304908
18E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.02791048
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.99441408
20* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.94583842
21RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.92531802
22FOXM1_23109430_ChIP-Seq_U2OS_Human1.91127171
23CIITA_25753668_ChIP-Seq_RAJI_Human1.86212071
24THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.81868010
25* VDR_24763502_ChIP-Seq_THP-1_Human1.79892057
26SPI1_23127762_ChIP-Seq_K562_Human1.72349860
27GATA1_19941827_ChIP-Seq_MEL_Mouse1.71337543
28RARG_19884340_ChIP-ChIP_MEFs_Mouse1.71173707
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.68856528
30STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62729608
31E2F7_22180533_ChIP-Seq_HELA_Human1.60247193
32BRD4_27068464_Chip-Seq_AML-cells_Mouse1.58219264
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57749312
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.55691645
35TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.53678941
36MYB_21317192_ChIP-Seq_ERMYB_Mouse1.53388466
37KDM2B_26808549_Chip-Seq_JURKAT_Human1.53039138
38MAF_26560356_Chip-Seq_TH2_Human1.50983811
39* RUNX1_22412390_ChIP-Seq_EML_Mouse1.50479378
40* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.49887319
41P68_20966046_ChIP-Seq_HELA_Human1.48874065
42GATA1_22383799_ChIP-Seq_G1ME_Mouse1.47683390
43RACK7_27058665_Chip-Seq_MCF-7_Human1.47143097
44NCOR1_26117541_ChIP-Seq_K562_Human1.43205515
45IRF8_21731497_ChIP-ChIP_J774_Mouse1.42538541
46BP1_19119308_ChIP-ChIP_Hs578T_Human1.41468020
47FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.41160386
48ELF1_20517297_ChIP-Seq_JURKAT_Human1.40496568
49* MYB_26560356_Chip-Seq_TH1_Human1.40432585
50* MYB_26560356_Chip-Seq_TH2_Human1.37140869
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.35389122
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.35154559
53SMC4_20622854_ChIP-Seq_HELA_Human1.32762324
54PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.32611361
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.30431210
56SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30415686
57KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.29830854
58IRF8_22096565_ChIP-ChIP_GC-B_Human1.29820166
59PU.1_20513432_ChIP-Seq_Bcells_Mouse1.29560895
60SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28618285
61KDM2B_26808549_Chip-Seq_K562_Human1.28063468
62BCL6_27268052_Chip-Seq_Bcells_Human1.27150954
63* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.24990877
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.24154434
65* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23883019
66BCOR_27268052_Chip-Seq_Bcells_Human1.23868116
67CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23739193
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23228229
69NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22686282
70CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.22539173
71* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.21072131
72ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.20993296
73ZFP281_27345836_Chip-Seq_ESCs_Mouse1.19584461
74MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.19524062
75ZNF263_19887448_ChIP-Seq_K562_Human1.19350261
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.18294574
77CTCF_27219007_Chip-Seq_ERYTHROID_Human1.17547457
78GATA1_19941826_ChIP-Seq_K562_Human1.17185366
79FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.16556355
80* SA1_27219007_Chip-Seq_ERYTHROID_Human1.16470933
81PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.16465750
82PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.16458144
83* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.16049063
84SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.15723183
85RUNX_20019798_ChIP-Seq_JUKART_Human1.15259950
86CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.14299478
87RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.14012333
88HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.13824447
89P300_27058665_Chip-Seq_ZR-75-30cells_Human1.13773602
90ATF3_27146783_Chip-Seq_COLON_Human1.12351517
91* CTCF_21964334_Chip-Seq_Bcells_Human1.12318106
92DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.12019977
93CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.11499420
94* IRF8_27001747_Chip-Seq_BMDM_Mouse1.10387180
95PHF8_20622854_ChIP-Seq_HELA_Human1.10226855
96LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.08144929
97CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.07940995
98GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07693374
99SPI1_23547873_ChIP-Seq_NB4_Human1.06420649
100CREB1_26743006_Chip-Seq_LNCaP_Human1.06288307
101FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.06216726
102KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.06188162
103* CTCF_26484167_Chip-Seq_Bcells_Mouse1.05733020
104SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.05227806
105CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.03622371
106TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.03431060
107UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02364027
108SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.01945542
109VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01932086
110SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01790100
111GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01577370
112SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01391185
113TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00712334
114ETS1_21867929_ChIP-Seq_TH2_Mouse1.00710907
115SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00350430
116TET1_21451524_ChIP-Seq_MESCs_Mouse0.99964887
117GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.99467387
118TBX20_22080862_ChIP-Seq_HEART_Mouse0.98901012
119TBX20_22328084_ChIP-Seq_HEART_Mouse0.98901012
120E2F1_20622854_ChIP-Seq_HELA_Human0.98886835
121SPI1_20517297_ChIP-Seq_HL60_Human0.98500099
122SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.98498987
123KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98235889

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009278_abnormal_bone_marrow3.20851575
2MP0005451_abnormal_body_composition3.12066883
3MP0003705_abnormal_hypodermis_morpholog2.69506071
4MP0003646_muscle_fatigue2.67370454
5MP0008260_abnormal_autophagy2.54199094
6MP0002396_abnormal_hematopoietic_system2.39561782
7MP0003724_increased_susceptibility_to2.35374379
8MP0004510_myositis2.30966321
9MP0003303_peritoneal_inflammation2.24815745
10MP0000685_abnormal_immune_system2.23518218
11MP0001545_abnormal_hematopoietic_system2.18378735
12MP0005397_hematopoietic_system_phenotyp2.18378735
13MP0003300_gastrointestinal_ulcer2.17155079
14MP0008961_abnormal_basal_metabolism2.15770915
15MP0004084_abnormal_cardiac_muscle2.11981491
16MP0000751_myopathy2.10028215
17MP0004808_abnormal_hematopoietic_stem2.09479740
18MP0010352_gastrointestinal_tract_polyps2.03264036
19MP0003436_decreased_susceptibility_to2.02469951
20MP0002837_dystrophic_cardiac_calcinosis1.93948502
21MP0002398_abnormal_bone_marrow1.86817366
22MP0009785_altered_susceptibility_to1.84240907
23MP0005076_abnormal_cell_differentiation1.83289528
24MP0004087_abnormal_muscle_fiber1.77993928
25MP0001800_abnormal_humoral_immune1.75953150
26MP0000749_muscle_degeneration1.74272941
27MP0003763_abnormal_thymus_physiology1.73933423
28MP0002148_abnormal_hypersensitivity_rea1.69212061
29MP0010630_abnormal_cardiac_muscle1.69163093
30MP0005464_abnormal_platelet_physiology1.68452600
31MP0000750_abnormal_muscle_regeneration1.65892570
32MP0002269_muscular_atrophy1.63661839
33MP0001533_abnormal_skeleton_physiology1.62827651
34MP0003656_abnormal_erythrocyte_physiolo1.62747429
35MP0000858_altered_metastatic_potential1.61800982
36MP0009840_abnormal_foam_cell1.61607529
37MP0004381_abnormal_hair_follicle1.61550272
38MP0001790_abnormal_immune_system1.60962798
39MP0005387_immune_system_phenotype1.60962798
40MP0002132_abnormal_respiratory_system1.59052796
41MP0003566_abnormal_cell_adhesion1.56270764
42MP0000689_abnormal_spleen_morphology1.55476747
43MP0004130_abnormal_muscle_cell1.54223874
44MP0000703_abnormal_thymus_morphology1.53942175
45MP0003172_abnormal_lysosome_physiology1.51874019
46MP0001835_abnormal_antigen_presentation1.51102842
47MP0002722_abnormal_immune_system1.51092684
48MP0004036_abnormal_muscle_relaxation1.45797867
49MP0003453_abnormal_keratinocyte_physiol1.45768042
50MP0000716_abnormal_immune_system1.45760945
51MP0003191_abnormal_cellular_cholesterol1.44720410
52MP0002106_abnormal_muscle_physiology1.43918466
53MP0003828_pulmonary_edema1.42475187
54MP0002452_abnormal_antigen_presenting1.41133605
55MP0004858_abnormal_nervous_system1.40428391
56MP0001849_ear_inflammation1.39336135
57MP0002420_abnormal_adaptive_immunity1.39283841
58MP0001819_abnormal_immune_cell1.38183894
59MP0002405_respiratory_system_inflammati1.37072675
60MP0002429_abnormal_blood_cell1.35788024
61MP0005330_cardiomyopathy1.33888797
62MP0000759_abnormal_skeletal_muscle1.32996013
63MP0002723_abnormal_immune_serum1.32977069
64MP0002653_abnormal_ependyma_morphology1.32567969
65MP0000678_abnormal_parathyroid_gland1.30659857
66MP0009333_abnormal_splenocyte_physiolog1.29304099
67MP0004233_abnormal_muscle_weight1.23821812
68MP0000747_muscle_weakness1.22704910
69MP0005671_abnormal_response_to1.20548114
70MP0005000_abnormal_immune_tolerance1.20480344
71MP0006082_CNS_inflammation1.19644250
72MP0002998_abnormal_bone_remodeling1.17904911
73MP0001873_stomach_inflammation1.17157102
74MP0000733_abnormal_muscle_development1.16467332
75MP0000465_gastrointestinal_hemorrhage1.14515012
76MP0003866_abnormal_defecation1.14508457
77MP0010155_abnormal_intestine_physiology1.14353439
78MP0004947_skin_inflammation1.14138969
79MP0003183_abnormal_peptide_metabolism1.12835267
80MP0005025_abnormal_response_to1.12490311
81MP0008775_abnormal_heart_ventricle1.11813713
82MP0005666_abnormal_adipose_tissue1.09974131
83MP0001853_heart_inflammation1.09817388
84MP0008469_abnormal_protein_level1.06633644
85MP0000266_abnormal_heart_morphology1.05604302
86MP0000490_abnormal_crypts_of1.03647838
87MP0005023_abnormal_wound_healing1.03319628
88MP0005375_adipose_tissue_phenotype1.02999583
89MP0002249_abnormal_larynx_morphology1.02743493
90MP0005670_abnormal_white_adipose1.01798294
91MP0002277_abnormal_respiratory_mucosa1.00433177
92MP0005369_muscle_phenotype0.99056853
93MP0005310_abnormal_salivary_gland0.98232284
94MP0001544_abnormal_cardiovascular_syste0.98182430
95MP0005385_cardiovascular_system_phenoty0.98182430
96MP0002166_altered_tumor_susceptibility0.97890502
97MP0004215_abnormal_myocardial_fiber0.96781678
98MP0003984_embryonic_growth_retardation0.96147732
99MP0002088_abnormal_embryonic_growth/wei0.94592444
100MP0002796_impaired_skin_barrier0.94048394
101MP0004264_abnormal_extraembryonic_tissu0.93570726
102MP0005409_darkened_coat_color0.93468662
103MP0004185_abnormal_adipocyte_glucose0.93317800
104MP0003279_aneurysm0.89785310
105MP0003221_abnormal_cardiomyocyte_apopto0.89647862
106MP0000343_altered_response_to0.88770777
107MP0002925_abnormal_cardiovascular_devel0.88678271
108MP0005058_abnormal_lysosome_morphology0.88647177
109MP0002419_abnormal_innate_immunity0.88608869
110MP0001851_eye_inflammation0.87640308
111MP0005390_skeleton_phenotype0.87302011
112MP0002019_abnormal_tumor_incidence0.86425099
113MP0009672_abnormal_birth_weight0.85606831
114MP0002086_abnormal_extraembryonic_tissu0.83035173
115MP0001845_abnormal_inflammatory_respons0.82667813
116MP0008770_decreased_survivor_rate0.81843765
117MP0000313_abnormal_cell_death0.80485396
118MP0002909_abnormal_adrenal_gland0.78892523
119MP0002970_abnormal_white_adipose0.78888794
120MP0002877_abnormal_melanocyte_morpholog0.78699474
121MP0001672_abnormal_embryogenesis/_devel0.78343460
122MP0005380_embryogenesis_phenotype0.78343460
123MP0003077_abnormal_cell_cycle0.78336540
124MP0001348_abnormal_lacrimal_gland0.78031660
125MP0003075_altered_response_to0.76752757
126MP0002972_abnormal_cardiac_muscle0.76557444
127MP0003091_abnormal_cell_migration0.76527897
128MP0005501_abnormal_skin_physiology0.75262226
129MP0009931_abnormal_skin_appearance0.75111018
130MP0002933_joint_inflammation0.74872711
131MP0000604_amyloidosis0.72177832
132MP0005083_abnormal_biliary_tract0.71347199
133MP0005621_abnormal_cell_physiology0.71258490
134MP0003329_amyloid_beta_deposits0.70386180
135MP0002009_preneoplasia0.69341269
136MP0003111_abnormal_nucleus_morphology0.67703665
137MP0001730_embryonic_growth_arrest0.67612016
138MP0001663_abnormal_digestive_system0.64603480
139MP0003448_altered_tumor_morphology0.62214285
140MP0008874_decreased_physiological_sensi0.61604237

Predicted human phenotypes

RankGene SetZ-score
1Recurrent bacterial skin infections (HP:0005406)4.00392368
2Abnormality of macrophages (HP:0004311)3.67395214
3Myositis (HP:0100614)3.42232946
4Ventricular tachycardia (HP:0004756)3.39812772
5Exercise-induced myalgia (HP:0003738)3.39406062
6Hyperacusis (HP:0010780)3.26024046
7Mediastinal lymphadenopathy (HP:0100721)3.23772151
8Asymmetric septal hypertrophy (HP:0001670)3.16285794
9Polycythemia (HP:0001901)3.08834445
10Colitis (HP:0002583)3.05539525
11Abnormality of the fingertips (HP:0001211)3.04873097
12Cellulitis (HP:0100658)3.04386760
13Chronic obstructive pulmonary disease (HP:0006510)3.04282621
14Obstructive lung disease (HP:0006536)3.04282621
15Nasal polyposis (HP:0100582)3.02593194
16Abnormality of the nasal mucosa (HP:0000433)3.01396825
17Orchitis (HP:0100796)2.99116543
18Meningitis (HP:0001287)2.98305428
19Sudden death (HP:0001699)2.96237816
20Cerebral aneurysm (HP:0004944)2.95201168
21Exercise-induced muscle cramps (HP:0003710)2.90210834
22Difficulty running (HP:0009046)2.88364110
23Verrucae (HP:0200043)2.87991581
24Papilloma (HP:0012740)2.87991581
25Gastrointestinal infarctions (HP:0005244)2.83250785
26Hyporeflexia of lower limbs (HP:0002600)2.75709677
27Recurrent viral infections (HP:0004429)2.75232496
28Gastrointestinal inflammation (HP:0004386)2.74796678
29Difficulty climbing stairs (HP:0003551)2.72771755
30Recurrent gram-negative bacterial infections (HP:0005420)2.71454394
31Increased connective tissue (HP:0009025)2.70341671
32Muscle fiber splitting (HP:0003555)2.59399767
33Inflammation of the large intestine (HP:0002037)2.57671775
34Panhypogammaglobulinemia (HP:0003139)2.56547062
35Chronic otitis media (HP:0000389)2.55299550
36Gingivitis (HP:0000230)2.54476040
37Increased density of long bones (HP:0006392)2.53353652
38Recurrent skin infections (HP:0001581)2.52862217
39Abnormal platelet function (HP:0011869)2.51623198
40Impaired platelet aggregation (HP:0003540)2.51623198
41Obstructive sleep apnea (HP:0002870)2.51226271
42Myoglobinuria (HP:0002913)2.48378979
43Subaortic stenosis (HP:0001682)2.43994080
44Abnormality of the left ventricular outflow tract (HP:0011103)2.43994080
45Gastrointestinal stroma tumor (HP:0100723)2.43825441
46Easy fatigability (HP:0003388)2.43789198
47Abnormal delayed hypersensitivity skin test (HP:0002963)2.41447684
48Hemorrhage of the eye (HP:0011885)2.40178495
49Optic neuritis (HP:0100653)2.38776943
50Retrobulbar optic neuritis (HP:0100654)2.38776943
51Vasculitis (HP:0002633)2.37025565
52Prolonged bleeding time (HP:0003010)2.36957513
53Bundle branch block (HP:0011710)2.36859537
54Urticaria (HP:0001025)2.36637859
55Dysmetric saccades (HP:0000641)2.35598981
56Broad face (HP:0000283)2.33378502
57Centrally nucleated skeletal muscle fibers (HP:0003687)2.32753848
58Recurrent fungal infections (HP:0002841)2.32282059
59Hypertensive crisis (HP:0100735)2.31035230
60Limb-girdle muscle atrophy (HP:0003797)2.30226865
61Ragged-red muscle fibers (HP:0003200)2.27395057
62Distal upper limb amyotrophy (HP:0007149)2.25379947
63Upper limb amyotrophy (HP:0009129)2.25379947
64Myopathic facies (HP:0002058)2.25149432
65Spontaneous hematomas (HP:0007420)2.25091971
66Chronic mucocutaneous candidiasis (HP:0002728)2.22968051
67Recurrent cutaneous fungal infections (HP:0011370)2.22968051
68Frequent falls (HP:0002359)2.20702436
69Autoimmune thrombocytopenia (HP:0001973)2.20428665
70Recurrent bronchitis (HP:0002837)2.20399148
71Agammaglobulinemia (HP:0004432)2.19347421
72Fatigue (HP:0012378)2.18918486
73Reticulocytosis (HP:0001923)2.17853744
74Loss of speech (HP:0002371)2.16157820
75Polygenic inheritance (HP:0010982)2.14040286
76Encephalitis (HP:0002383)2.12418453
77Hand muscle atrophy (HP:0009130)2.12244232
78Metaphyseal cupping (HP:0003021)2.10258338
79Thoracic kyphosis (HP:0002942)2.10163211
80Stomatitis (HP:0010280)2.09357597
81EMG: myopathic abnormalities (HP:0003458)2.08707198
82Broad distal phalanx of finger (HP:0009836)2.05968219
83EMG: neuropathic changes (HP:0003445)2.05182065
84Segmental peripheral demyelination/remyelination (HP:0003481)2.04967894
85Long eyelashes (HP:0000527)2.04776676
86Abnormality of the columella (HP:0009929)2.03381579
87Abnormality of the thoracic spine (HP:0100711)2.02598055
88Petechiae (HP:0000967)2.00224477
89Hypochromic anemia (HP:0001931)1.99865820
90Long toe (HP:0010511)1.99236107
91Neuronal loss in central nervous system (HP:0002529)1.99146031
92Lymphopenia (HP:0001888)1.99010581
93Long palpebral fissure (HP:0000637)1.98625065
94Distal lower limb muscle weakness (HP:0009053)1.97732621
95Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.97310874
96Chest pain (HP:0100749)1.97103250
97Elevated erythrocyte sedimentation rate (HP:0003565)1.96552014
98Broad palm (HP:0001169)1.95833191
99Slow saccadic eye movements (HP:0000514)1.95329604
100Atrial fibrillation (HP:0005110)1.93981267
101Aneurysm (HP:0002617)1.91982875
102Thin bony cortex (HP:0002753)1.91609022
103Abnormality of cells of the lymphoid lineage (HP:0012140)1.91590218
104Bicuspid aortic valve (HP:0001647)1.90820086
105Increased cerebral lipofuscin (HP:0011813)1.89925300
106Increased IgM level (HP:0003496)1.89704411
107Atrioventricular block (HP:0001678)1.89668159
108Ulnar bowing (HP:0003031)1.88403094
109Macroorchidism (HP:0000053)1.88344834
110Increased serum ferritin (HP:0003281)1.88024100
111Lipoatrophy (HP:0100578)1.87907401
112Abnormality of the lower motor neuron (HP:0002366)1.87258066
113Primary atrial arrhythmia (HP:0001692)1.86113523
114Ulnar deviation of the wrist (HP:0003049)1.86110605
115Axonal loss (HP:0003447)1.85141091
116Pustule (HP:0200039)1.84855623
117Supraventricular tachycardia (HP:0004755)1.84347910
118Large for gestational age (HP:0001520)1.83284756
119Abnormality of T cell physiology (HP:0011840)1.81753821
120Heart block (HP:0012722)1.81403548
121Supraventricular arrhythmia (HP:0005115)1.81263753
122Insomnia (HP:0100785)1.80711843
123Sepsis (HP:0100806)1.80137987
124Progressive external ophthalmoplegia (HP:0000590)1.79927237
125Osteomyelitis (HP:0002754)1.79587458
126Calf muscle hypertrophy (HP:0008981)1.79197173
127Dislocated radial head (HP:0003083)1.77954238
128IgM deficiency (HP:0002850)1.77859646
129Rhabdomyolysis (HP:0003201)1.77587597
130Abnormality of skeletal muscle fiber size (HP:0012084)1.77166026
131Distal lower limb amyotrophy (HP:0008944)1.77125926
132Elfin facies (HP:0004428)1.76380658
133Recurrent abscess formation (HP:0002722)1.76142416
134Granulocytopenia (HP:0001913)1.75882129
135Basal cell carcinoma (HP:0002671)1.75800407
136Interstitial pulmonary disease (HP:0006530)1.74962914
137Hypercortisolism (HP:0001578)1.74894897
138Purpura (HP:0000979)1.74633542
139Emphysema (HP:0002097)1.73980278
140Annular pancreas (HP:0001734)1.73941953
141Increased IgE level (HP:0003212)1.73479195
142Neoplasm of the heart (HP:0100544)1.72978715
143Dysostosis multiplex (HP:0000943)1.72889267
144Viral hepatitis (HP:0006562)1.72360851
145Thrombocytosis (HP:0001894)1.71928222
146Keratoconjunctivitis sicca (HP:0001097)1.71762237
147Recurrent otitis media (HP:0000403)1.71656560
148Epistaxis (HP:0000421)1.71237665
149Abnormality of the radial head (HP:0003995)1.70757443
150Premature loss of primary teeth (HP:0006323)1.70317657
151Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.69595488
152Abnormal atrioventricular conduction (HP:0005150)1.69566941
153Right ventricular cardiomyopathy (HP:0011663)1.68908388
154Hypertriglyceridemia (HP:0002155)1.68016422
155Pointed chin (HP:0000307)1.67956235
156Dilated cardiomyopathy (HP:0001644)1.67670363
157Depressed nasal tip (HP:0000437)1.67605536
158Restrictive lung disease (HP:0002091)1.67505643
159Prominent nose (HP:0000448)1.65956031
160Eczematoid dermatitis (HP:0000976)1.65951955
161Disproportionate tall stature (HP:0001519)1.65381189
162Increased variability in muscle fiber diameter (HP:0003557)1.64629065
163Abnormality of T cells (HP:0002843)1.64624093
164Late onset (HP:0003584)1.64253354
165Myotonia (HP:0002486)1.64106453

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K104.20269158
2TRIB34.17408342
3EEF2K3.66342461
4ERN13.55979862
5MAP4K13.41962271
6PRPF4B3.39396653
7SMG13.17482894
8CDK123.08970764
9PKN22.77368592
10TTN2.57068473
11RIPK42.46132950
12ICK2.01785478
13IRAK41.97012280
14TAOK11.92657022
15SIK21.80932561
16IRAK31.69433462
17BLK1.64186861
18DMPK1.58814071
19STK101.54637473
20MAP2K31.51496436
21TESK21.51466897
22PRKD31.50403590
23RIPK11.48598377
24MAPKAPK31.42834927
25TNK21.42279587
26SIK11.39399406
27PTK61.37438979
28TYK21.37168107
29MAP3K141.32053970
30MAP3K31.30320439
31MAP3K71.30194995
32TGFBR21.27293599
33PRKD21.25971009
34ZAP701.25156150
35FES1.24941779
36GRK61.21790225
37LRRK21.17301680
38MAP3K111.09699621
39CSF1R1.07502319
40BTK1.06594510
41JAK31.06582748
42ALK1.03010357
43IRAK21.00297158
44RPS6KA41.00007915
45NEK20.98960639
46HIPK20.98820396
47BMX0.98590748
48MTOR0.95722754
49NME20.94016703
50CAMK1G0.93648047
51HCK0.92501725
52CAMK1D0.90859322
53CDK40.90356122
54TBK10.86762710
55SIK30.86068042
56RPS6KB20.85394195
57MARK20.81799304
58EPHB10.81475229
59SYK0.81234048
60KIT0.80514079
61MAP2K20.80478612
62PRKCH0.77720921
63PDPK10.76285412
64DYRK1B0.76174440
65PHKG10.75796252
66PHKG20.75796252
67FGFR40.75718573
68DYRK30.75532083
69JAK10.74536239
70RPS6KA60.72591855
71PIM10.71824996
72NEK10.71202026
73TESK10.70895339
74RPS6KC10.70886834
75RPS6KL10.70886834
76CAMK40.68519556
77JAK20.68023349
78EPHA20.67917089
79TAOK20.67911043
80KSR20.67417063
81FGR0.67379422
82PRKD10.66173596
83CSK0.65952217
84MAPK120.65838767
85ITK0.64824375
86PAK40.64682535
87RPS6KA20.61052413
88MAPK110.60904577
89LYN0.60399992
90MAPK70.60000852
91TYRO30.59220797
92CDK190.57506156
93MATK0.56478819
94PDGFRA0.56201855
95MAP3K10.55509132
96PDK10.55459756
97CLK10.55382274
98IKBKB0.54922657
99MAP3K80.53493379
100MAPK150.52738557
101CHUK0.51988046
102SGK30.51103847
103MAPKAPK20.51096870
104STK40.50240776
105MAP3K130.49237228
106CDK60.48728013
107ARAF0.48206534
108TAOK30.48058547
109CDK70.47887900
110CDK90.47720636
111MARK30.47584265
112MELK0.46172466
113RPS6KA10.46131737
114LMTK20.46063123
115CDC42BPA0.43529740
116BRD40.43037504
117PRKAA10.42559419
118LCK0.42222769
119ILK0.41461279
120STK380.41218394
121RAF10.40875675
122CAMK10.39661317
123MAP3K60.39082384
124RET0.38540929
125KDR0.38324087
126PIM20.38152767
127IKBKE0.38027658
128PRKG20.37868201
129IRAK10.32670967
130BCKDK0.31472586

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.42514246
2Acute myeloid leukemia_Homo sapiens_hsa052212.28912365
3Chronic myeloid leukemia_Homo sapiens_hsa052202.16009865
4Primary immunodeficiency_Homo sapiens_hsa053402.10768097
5Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.89448262
6Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.87664894
7Lysine degradation_Homo sapiens_hsa003101.85838412
8mTOR signaling pathway_Homo sapiens_hsa041501.66052818
9Osteoclast differentiation_Homo sapiens_hsa043801.64341960
10Non-small cell lung cancer_Homo sapiens_hsa052231.60958828
11Insulin resistance_Homo sapiens_hsa049311.56831915
12Allograft rejection_Homo sapiens_hsa053301.56740165
13Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.54151752
14Leishmaniasis_Homo sapiens_hsa051401.53578609
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.50151316
16Graft-versus-host disease_Homo sapiens_hsa053321.49710634
17Viral myocarditis_Homo sapiens_hsa054161.49522007
18VEGF signaling pathway_Homo sapiens_hsa043701.48209229
19Autoimmune thyroid disease_Homo sapiens_hsa053201.48167468
202-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.46789079
21Hepatitis C_Homo sapiens_hsa051601.45722420
22Sulfur relay system_Homo sapiens_hsa041221.44632016
23Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.43077188
24Staphylococcus aureus infection_Homo sapiens_hsa051501.41369329
25Notch signaling pathway_Homo sapiens_hsa043301.39609955
26Neurotrophin signaling pathway_Homo sapiens_hsa047221.38960120
27Thyroid hormone signaling pathway_Homo sapiens_hsa049191.37345690
28Dilated cardiomyopathy_Homo sapiens_hsa054141.33944529
29Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.31842611
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.29551797
31Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.28182916
32T cell receptor signaling pathway_Homo sapiens_hsa046601.28100422
33Toxoplasmosis_Homo sapiens_hsa051451.27883725
34Pancreatic cancer_Homo sapiens_hsa052121.27568091
35Insulin signaling pathway_Homo sapiens_hsa049101.27197498
36Longevity regulating pathway - mammal_Homo sapiens_hsa042111.23916693
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.19470052
38Central carbon metabolism in cancer_Homo sapiens_hsa052301.18475386
39Platelet activation_Homo sapiens_hsa046111.14948263
40Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.14709387
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.14205699
42Shigellosis_Homo sapiens_hsa051311.14101127
43Adipocytokine signaling pathway_Homo sapiens_hsa049201.12690394
44Endometrial cancer_Homo sapiens_hsa052131.11310177
45Measles_Homo sapiens_hsa051621.11278662
46Colorectal cancer_Homo sapiens_hsa052101.11172516
47Epstein-Barr virus infection_Homo sapiens_hsa051691.11072500
48Malaria_Homo sapiens_hsa051441.10496522
49Hepatitis B_Homo sapiens_hsa051611.10262202
50AMPK signaling pathway_Homo sapiens_hsa041521.08797431
51Apoptosis_Homo sapiens_hsa042101.06222256
52Prolactin signaling pathway_Homo sapiens_hsa049171.05518450
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.03596138
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.03194606
55HTLV-I infection_Homo sapiens_hsa051661.03006192
56Jak-STAT signaling pathway_Homo sapiens_hsa046301.02965854
57Glucagon signaling pathway_Homo sapiens_hsa049221.02543594
58Leukocyte transendothelial migration_Homo sapiens_hsa046701.01038975
59HIF-1 signaling pathway_Homo sapiens_hsa040661.00617358
60NOD-like receptor signaling pathway_Homo sapiens_hsa046211.00268051
61Small cell lung cancer_Homo sapiens_hsa052220.99798758
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.98715137
63NF-kappa B signaling pathway_Homo sapiens_hsa040640.95462524
64Type II diabetes mellitus_Homo sapiens_hsa049300.95082812
65Proteoglycans in cancer_Homo sapiens_hsa052050.95069298
66Antigen processing and presentation_Homo sapiens_hsa046120.93100877
67Base excision repair_Homo sapiens_hsa034100.92098717
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.91299052
69Herpes simplex infection_Homo sapiens_hsa051680.89906171
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89753119
71Biosynthesis of amino acids_Homo sapiens_hsa012300.89732146
72Glioma_Homo sapiens_hsa052140.87998949
73Influenza A_Homo sapiens_hsa051640.87847324
74Type I diabetes mellitus_Homo sapiens_hsa049400.85104191
75Fructose and mannose metabolism_Homo sapiens_hsa000510.84253037
76Tuberculosis_Homo sapiens_hsa051520.83943348
77Glycosaminoglycan degradation_Homo sapiens_hsa005310.83624438
78Toll-like receptor signaling pathway_Homo sapiens_hsa046200.82579343
79Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.82362423
80Prostate cancer_Homo sapiens_hsa052150.81710796
81Choline metabolism in cancer_Homo sapiens_hsa052310.81272164
82Hematopoietic cell lineage_Homo sapiens_hsa046400.80022133
83Focal adhesion_Homo sapiens_hsa045100.78298013
84ErbB signaling pathway_Homo sapiens_hsa040120.77876767
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.77148908
86Carbon metabolism_Homo sapiens_hsa012000.76917034
87Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.76527204
88Thyroid cancer_Homo sapiens_hsa052160.75007083
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.74776344
90Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.73942810
91Lysosome_Homo sapiens_hsa041420.73602929
92Chemokine signaling pathway_Homo sapiens_hsa040620.73300648
93TNF signaling pathway_Homo sapiens_hsa046680.72455517
94FoxO signaling pathway_Homo sapiens_hsa040680.71682765
95Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70701668
96Regulation of actin cytoskeleton_Homo sapiens_hsa048100.70578667
97Phagosome_Homo sapiens_hsa041450.70278348
98Pertussis_Homo sapiens_hsa051330.69487194
99Endocytosis_Homo sapiens_hsa041440.69362923
100MicroRNAs in cancer_Homo sapiens_hsa052060.68084052
101Renal cell carcinoma_Homo sapiens_hsa052110.65760380
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65270936
103Dorso-ventral axis formation_Homo sapiens_hsa043200.64724452
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.63566523
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.63231377
106Other glycan degradation_Homo sapiens_hsa005110.62762197
107Legionellosis_Homo sapiens_hsa051340.62623727
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61693627
109RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.61494992
110Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61396599
111GnRH signaling pathway_Homo sapiens_hsa049120.60966665
112Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.59879590
113Viral carcinogenesis_Homo sapiens_hsa052030.59864020
114Phosphatidylinositol signaling system_Homo sapiens_hsa040700.59788654
115Galactose metabolism_Homo sapiens_hsa000520.58158771
116Pentose phosphate pathway_Homo sapiens_hsa000300.57940116
117mRNA surveillance pathway_Homo sapiens_hsa030150.57935596
118African trypanosomiasis_Homo sapiens_hsa051430.56446310
119Bladder cancer_Homo sapiens_hsa052190.56009335
120Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55898020
121MAPK signaling pathway_Homo sapiens_hsa040100.55724070
122Estrogen signaling pathway_Homo sapiens_hsa049150.54599465
123Amoebiasis_Homo sapiens_hsa051460.54566240
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52421097
125Inositol phosphate metabolism_Homo sapiens_hsa005620.51002695
126Salmonella infection_Homo sapiens_hsa051320.50553188
127Prion diseases_Homo sapiens_hsa050200.50489423

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