CCER1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1reproduction (GO:0000003)9.94511817
2spermatid development (GO:0007286)9.76201020
3motile cilium assembly (GO:0044458)9.52292635
4regulation of cilium movement (GO:0003352)8.55200448
5cilium movement (GO:0003341)8.53663300
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.87809506
7single fertilization (GO:0007338)7.56720509
8sperm capacitation (GO:0048240)7.49594307
9synaptonemal complex organization (GO:0070193)7.28696718
10male meiosis (GO:0007140)7.27843886
11synaptonemal complex assembly (GO:0007130)7.11096287
12piRNA metabolic process (GO:0034587)6.98871956
13negative regulation of inclusion body assembly (GO:0090084)6.86735769
14spermatogenesis (GO:0007283)6.43316154
15male gamete generation (GO:0048232)6.40947281
16fertilization (GO:0009566)6.33891429
17spermatid nucleus differentiation (GO:0007289)6.19819307
18microtubule depolymerization (GO:0007019)6.18500678
19organic cation transport (GO:0015695)6.14374714
20establishment of protein localization to Golgi (GO:0072600)6.01511511
21protein targeting to Golgi (GO:0000042)5.91777869
22gamete generation (GO:0007276)5.89240279
23regulation of inclusion body assembly (GO:0090083)5.75600570
24response to pheromone (GO:0019236)5.68303189
25calcium ion-dependent exocytosis (GO:0017156)5.57300267
26retrograde transport, vesicle recycling within Golgi (GO:0000301)5.47014441
27germ cell development (GO:0007281)5.41314833
28cellular process involved in reproduction in multicellular organism (GO:0022412)5.32151535
29sexual reproduction (GO:0019953)5.31325168
30ventricular system development (GO:0021591)5.28390550
31regulation of microtubule-based movement (GO:0060632)5.03030034
32cell recognition (GO:0008037)5.00973097
33single strand break repair (GO:0000012)4.87935771
34glycerol ether metabolic process (GO:0006662)4.87656611
35chromosome organization involved in meiosis (GO:0070192)4.82880830
36microtubule severing (GO:0051013)4.73988131
37male meiosis I (GO:0007141)4.72751631
38phosphatidylethanolamine biosynthetic process (GO:0006646)4.66389539
39multicellular organismal reproductive process (GO:0048609)4.64428246
40ether metabolic process (GO:0018904)4.50715377
41DNA methylation involved in gamete generation (GO:0043046)4.49201755
42regulation of centriole replication (GO:0046599)4.44524567
43chromosome condensation (GO:0030261)4.43585162
44regulation of Rab GTPase activity (GO:0032313)4.37634545
45positive regulation of Rab GTPase activity (GO:0032851)4.37634545
46meiotic nuclear division (GO:0007126)4.31914418
47rRNA methylation (GO:0031167)4.30956225
48left/right pattern formation (GO:0060972)4.27115217
49phosphatidylethanolamine metabolic process (GO:0046337)4.22138502
50seminiferous tubule development (GO:0072520)4.21391719
51DNA packaging (GO:0006323)4.18696470
52protein localization to Golgi apparatus (GO:0034067)4.16585828
53protein K11-linked deubiquitination (GO:0035871)3.92904331
54monoubiquitinated protein deubiquitination (GO:0035520)3.89691512
55meiosis I (GO:0007127)3.75647974
56chaperone-mediated protein complex assembly (GO:0051131)3.74694376
57regulation of transcription involved in cell fate commitment (GO:0060850)3.74332548
58multicellular organismal movement (GO:0050879)3.73129486
59musculoskeletal movement (GO:0050881)3.73129486
60genitalia morphogenesis (GO:0035112)3.72964011
61multicellular organismal development (GO:0007275)3.71355493
62cellular ketone body metabolic process (GO:0046950)3.66518560
63rRNA modification (GO:0000154)3.62434563
64regulation of phosphoprotein phosphatase activity (GO:0043666)3.47892157
65protein polyglutamylation (GO:0018095)3.47108160
66RNA destabilization (GO:0050779)3.40498497
67protein refolding (GO:0042026)3.38853611
68peptidyl-threonine dephosphorylation (GO:0035970)3.38062759
69primary amino compound metabolic process (GO:1901160)3.29718089
70histone H3-K9 demethylation (GO:0033169)3.29690602
71meiotic cell cycle (GO:0051321)3.29453204
72detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.26030249
73glycolytic process (GO:0006096)3.24205269
74microtubule polymerization or depolymerization (GO:0031109)3.22274769
75ketone body metabolic process (GO:1902224)3.20826444
76cellular response to pH (GO:0071467)3.20124214
77nucleus organization (GO:0006997)3.17286415
78Golgi to endosome transport (GO:0006895)3.11566682
79sequestering of actin monomers (GO:0042989)3.08176136
80amino-acid betaine transport (GO:0015838)3.05175346
81carnitine transport (GO:0015879)3.05175346
82resolution of meiotic recombination intermediates (GO:0000712)3.03535359
83protein localization to cilium (GO:0061512)3.01749325
84coenzyme catabolic process (GO:0009109)3.01089476
85regulation of spindle checkpoint (GO:0090231)2.98710149
86NAD biosynthetic process (GO:0009435)2.98580375
87regulation of female gonad development (GO:2000194)2.98290750
88mesenchymal cell differentiation involved in renal system development (GO:2001012)2.94788976
89mesenchymal cell differentiation involved in kidney development (GO:0072161)2.94788976
90cilium organization (GO:0044782)2.94249434
91polyol catabolic process (GO:0046174)2.92216039
92carnitine transmembrane transport (GO:1902603)2.90679972
93positive regulation of guanylate cyclase activity (GO:0031284)2.90330007
94nucleoside diphosphate phosphorylation (GO:0006165)2.89258161
95microtubule-based movement (GO:0007018)2.86213065
96serotonin metabolic process (GO:0042428)2.85304955
97alditol metabolic process (GO:0019400)2.84768714
98response to acidic pH (GO:0010447)2.84345774
99cilium assembly (GO:0042384)2.82401895
100mitotic sister chromatid cohesion (GO:0007064)2.81097001
101positive regulation of action potential (GO:0045760)2.80307369
102regulation of ARF GTPase activity (GO:0032312)2.79520692
103meiotic cell cycle process (GO:1903046)2.77975678
104positive regulation of macrophage activation (GO:0043032)2.77803351
105microtubule nucleation (GO:0007020)2.76825077
106peptidyl-glutamic acid modification (GO:0018200)2.76315220
107centriole assembly (GO:0098534)2.75634018
108chromatin silencing (GO:0006342)2.75534428
109glomerular visceral epithelial cell development (GO:0072015)2.75526894
110phosphatidylserine acyl-chain remodeling (GO:0036150)2.75207724
111regulation of guanylate cyclase activity (GO:0031282)2.74542697
112cellular component assembly involved in morphogenesis (GO:0010927)2.72463713
113intraciliary transport (GO:0042073)2.71635732
114interferon-gamma secretion (GO:0072643)2.71572109
115protein K48-linked deubiquitination (GO:0071108)2.70820890
116lactate metabolic process (GO:0006089)2.70193027
117synapsis (GO:0007129)2.69385833
118phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.66835943
119membrane depolarization during action potential (GO:0086010)2.66281856
120GTP biosynthetic process (GO:0006183)2.61652436
121negative regulation of organelle assembly (GO:1902116)2.60500700
122axoneme assembly (GO:0035082)2.60089350
123glomerular epithelial cell development (GO:0072310)2.57119483
124cilium morphogenesis (GO:0060271)2.56346071
125RNA localization (GO:0006403)2.53912132
126gene silencing by RNA (GO:0031047)2.53662914
127nucleosome disassembly (GO:0006337)2.51167934
128protein-DNA complex disassembly (GO:0032986)2.51167934
129polyamine biosynthetic process (GO:0006596)2.49004324
130centriole replication (GO:0007099)2.48821998
131gene silencing (GO:0016458)2.42471809
132sperm motility (GO:0030317)14.0793503
133cell wall macromolecule metabolic process (GO:0044036)13.8427724
134cell wall macromolecule catabolic process (GO:0016998)13.8427724
135fusion of sperm to egg plasma membrane (GO:0007342)13.5864799
136acrosome reaction (GO:0007340)11.8670815
137sperm-egg recognition (GO:0035036)11.5358446
138multicellular organism reproduction (GO:0032504)11.2685086
139acrosome assembly (GO:0001675)11.1897873
140epithelial cilium movement (GO:0003351)10.5497020
141binding of sperm to zona pellucida (GO:0007339)10.4798343
142plasma membrane fusion (GO:0045026)10.3683787
143cell-cell recognition (GO:0009988)10.3463936
144axonemal dynein complex assembly (GO:0070286)10.1744262
145cilium or flagellum-dependent cell motility (GO:0001539)10.0052431

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.49001501
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.00562069
3EZH2_22144423_ChIP-Seq_EOC_Human3.86960465
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.54830398
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.98025641
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.75300637
7PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.72862971
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.58366903
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.44732038
10AR_21572438_ChIP-Seq_LNCaP_Human2.34391731
11VDR_22108803_ChIP-Seq_LS180_Human2.30914103
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.26894457
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.23952700
14CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.22675986
15DROSHA_22980978_ChIP-Seq_HELA_Human2.21434654
16CTBP1_25329375_ChIP-Seq_LNCAP_Human2.20806111
17GBX2_23144817_ChIP-Seq_PC3_Human2.08306933
18IGF1R_20145208_ChIP-Seq_DFB_Human2.05820293
19GATA1_26923725_Chip-Seq_HPCs_Mouse2.03066246
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.02470923
21EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.02072162
22PCGF2_27294783_Chip-Seq_ESCs_Mouse1.93548078
23VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.89048607
24KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.86558956
25ZNF274_21170338_ChIP-Seq_K562_Hela1.79909883
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.77900468
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.77285599
28RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.77234347
29TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.76167159
30FUS_26573619_Chip-Seq_HEK293_Human1.74029543
31STAT1_17558387_ChIP-Seq_HELA_Human1.71714256
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.68211389
33GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66443232
34ELK4_26923725_Chip-Seq_MESODERM_Mouse1.65378834
35MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.63209622
36KAP1_22055183_ChIP-Seq_ESCs_Mouse1.62000799
37KDM2B_26808549_Chip-Seq_REH_Human1.61441278
38ER_23166858_ChIP-Seq_MCF-7_Human1.61151495
39GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.61011510
40AR_25329375_ChIP-Seq_VCAP_Human1.59736204
41FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59601277
42SMAD3_21741376_ChIP-Seq_EPCs_Human1.59549444
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.58412770
44TAL1_26923725_Chip-Seq_HPCs_Mouse1.56906627
45SMAD4_21799915_ChIP-Seq_A2780_Human1.55052508
46WDR5_24793694_ChIP-Seq_LNCAP_Human1.54405647
47SOX2_22085726_ChIP-Seq_NPCs_Mouse1.53896532
48ARNT_22903824_ChIP-Seq_MCF-7_Human1.50732860
49CBP_20019798_ChIP-Seq_JUKART_Human1.48781576
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48781576
51P300_19829295_ChIP-Seq_ESCs_Human1.48446458
52PCGF2_27294783_Chip-Seq_NPCs_Mouse1.47374584
53GATA3_21867929_ChIP-Seq_CD8_Mouse1.45642426
54ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.45369807
55JARID2_20075857_ChIP-Seq_MESCs_Mouse1.43377372
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41241801
57SMAD4_21741376_ChIP-Seq_EPCs_Human1.40545998
58EED_16625203_ChIP-ChIP_MESCs_Mouse1.40514723
59STAT3_23295773_ChIP-Seq_U87_Human1.40431509
60NFE2_27457419_Chip-Seq_LIVER_Mouse1.40262744
61SUZ12_27294783_Chip-Seq_ESCs_Mouse1.38730704
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.36007050
63EZH2_27294783_Chip-Seq_ESCs_Mouse1.35752799
64NANOG_20526341_ChIP-Seq_ESCs_Human1.34455448
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33910946
66CTCF_27219007_Chip-Seq_Bcells_Human1.33627340
67SMAD3_21741376_ChIP-Seq_ESCs_Human1.33440940
68CTBP2_25329375_ChIP-Seq_LNCAP_Human1.32325764
69RUNX2_22187159_ChIP-Seq_PCA_Human1.31979906
70SUZ12_27294783_Chip-Seq_NPCs_Mouse1.31976058
71SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.31620432
72REST_21632747_ChIP-Seq_MESCs_Mouse1.31564531
73GATA3_21867929_ChIP-Seq_TH1_Mouse1.31451811
74EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.31316621
75ERA_21632823_ChIP-Seq_H3396_Human1.31287947
76EZH2_27304074_Chip-Seq_ESCs_Mouse1.30824624
77RAC3_21632823_ChIP-Seq_H3396_Human1.30639261
78LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.29860168
79PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.28521741
80TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.28486265
81P53_21459846_ChIP-Seq_SAOS-2_Human1.28205801
82ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28203387
83TBL1_22424771_ChIP-Seq_293T_Human1.28040645
84TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27252594
85FLI1_21867929_ChIP-Seq_TH2_Mouse1.26418406
86BMI1_23680149_ChIP-Seq_NPCS_Mouse1.25950656
87OCT4_20526341_ChIP-Seq_ESCs_Human1.24754388
88FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.24614667
89SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.23951097
90SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.23723060
91MYC_19829295_ChIP-Seq_ESCs_Human1.23198315
92MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21005201
93TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20017028
94POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20017028
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.19261259
96CRX_20693478_ChIP-Seq_RETINA_Mouse1.17827542
97ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.16984205
98GF1_26923725_Chip-Seq_HPCs_Mouse1.14844875
99OCT1_27270436_Chip-Seq_PROSTATE_Human1.14457721
100RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.14296063
101CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.14098323
102AUTS2_25519132_ChIP-Seq_293T-REX_Human1.13450798
103JARID2_20064375_ChIP-Seq_MESCs_Mouse1.13117835
104PRDM14_20953172_ChIP-Seq_ESCs_Human1.13093911
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12954043
106OCT4_18555785_Chip-Seq_ESCs_Mouse1.12016743
107RUNX1_26923725_Chip-Seq_HPCs_Mouse1.11807853
108RAD21_21589869_ChIP-Seq_MESCs_Mouse1.11571173
109EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.11243346
110CMYC_18555785_Chip-Seq_ESCs_Mouse1.11201632
111TAF15_26573619_Chip-Seq_HEK293_Human1.10655465
112SMAD4_21741376_ChIP-Seq_HESCs_Human1.10571384
113P53_22387025_ChIP-Seq_ESCs_Mouse1.10382353
114ELF1_20517297_ChIP-Seq_JURKAT_Human1.09689550
115CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.09534971
116EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09278210
117AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08979739
118MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.08848737
119TDRD3_21172665_ChIP-Seq_MCF-7_Human1.08679715
120SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.08634679
121TP53_18474530_ChIP-ChIP_U2OS_Human1.08411519
122SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.07992645
123SPI1_26923725_Chip-Seq_HPCs_Mouse1.07892408
124PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.07869940
125TCF4_23295773_ChIP-Seq_U87_Human1.07213182
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07064586
127CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.06570451
128RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.06281184
129CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06277080
130SMC4_20622854_ChIP-Seq_HELA_Human1.06019812
131KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.05988040
132PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05210884
133AHR_22903824_ChIP-Seq_MCF-7_Human1.04755515
134CBX2_22325352_ChIP-Seq_293T-Rex_Human1.04731127
135P300_18555785_Chip-Seq_ESCs_Mouse1.04655647
136PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.04403108
137HNFA_21074721_ChIP-Seq_CACO-2_Human1.04367123
138SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.04283111
139FOXH1_21741376_ChIP-Seq_EPCs_Human1.03936834
140ESET_19884257_ChIP-Seq_ESCs_Mouse1.03625956
141NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02813227
142E2F1_20622854_ChIP-Seq_HELA_Human1.02032651
143RBPJ_21746931_ChIP-Seq_IB4_Human1.01823870
144PHF8_20622853_ChIP-Seq_HELA_Human1.01317029
145SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00844269
146CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00460307
147ERG_20517297_ChIP-Seq_VCAP_Human1.00434501
148SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.00100286
149CTCF_20526341_ChIP-Seq_ESCs_Human0.99997815
150ETV1_20927104_ChIP-Seq_GIST48_Human0.99353822
151KLF4_18555785_Chip-Seq_ESCs_Mouse0.99316596
152NFYA_21822215_ChIP-Seq_K562_Human0.98984403
153EZH2_18974828_ChIP-Seq_MESCs_Mouse0.98908083
154RNF2_18974828_ChIP-Seq_MESCs_Mouse0.98908083
155OCT4_21477851_ChIP-Seq_ESCs_Mouse0.98858740
156PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.98556452
157SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.98422214
158SOX9_26525672_Chip-Seq_HEART_Mouse0.97470431
159EZH2_27294783_Chip-Seq_NPCs_Mouse0.96818041
160SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95767895
161GATA1_19941827_ChIP-Seq_MEL86_Mouse0.95749244
162ESRRB_18555785_Chip-Seq_ESCs_Mouse0.95498507
163YY1_22570637_ChIP-Seq_MALME-3M_Human0.94833857
164NFYB_21822215_ChIP-Seq_K562_Human0.93894498
165EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93404546
166SUZ12_18555785_Chip-Seq_ESCs_Mouse0.92792247
167RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.92340887
168STAT3_18555785_Chip-Seq_ESCs_Mouse0.91188914
169RNF2_27304074_Chip-Seq_NSC_Mouse0.90940199
170RARA_24833708_ChIP-Seq_LIVER_Mouse0.90877700
171RXRA_24833708_ChIP-Seq_LIVER_Mouse0.90164258
172MYC_27129775_Chip-Seq_CORNEA_Mouse0.89694118
173GF1B_26923725_Chip-Seq_HPCs_Mouse0.89214207
174SOX2_18555785_Chip-Seq_ESCs_Mouse0.89133728
175LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.89116523

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.20167141
2MP0001929_abnormal_gametogenesis5.60135664
3MP0008877_abnormal_DNA_methylation4.19261371
4MP0002210_abnormal_sex_determination3.49089054
5MP0002161_abnormal_fertility/fecundity3.38625695
6MP0001145_abnormal_male_reproductive2.95640986
7MP0005670_abnormal_white_adipose2.79411424
8MP0001348_abnormal_lacrimal_gland2.77062262
9MP0001905_abnormal_dopamine_level2.67981257
10MP0000653_abnormal_sex_gland2.55949125
11MP0002653_abnormal_ependyma_morphology2.44498281
12MP0001485_abnormal_pinna_reflex2.31313780
13MP0001486_abnormal_startle_reflex2.26918320
14MP0005410_abnormal_fertilization16.3876489
15MP0001440_abnormal_grooming_behavior1.99061099
16MP0005310_abnormal_salivary_gland1.90942011
17MP0002822_catalepsy1.82401918
18MP0003718_maternal_effect1.79934694
19MP0005083_abnormal_biliary_tract1.77385222
20MP0003183_abnormal_peptide_metabolism1.71905071
21MP0005623_abnormal_meninges_morphology1.64326848
22MP0002735_abnormal_chemical_nociception1.61270367
23MP0009745_abnormal_behavioral_response1.58772225
24MP0009053_abnormal_anal_canal1.58648914
25MP0001501_abnormal_sleep_pattern1.54132230
26MP0001963_abnormal_hearing_physiology1.53757295
27MP0002572_abnormal_emotion/affect_behav1.49794358
28MP0002160_abnormal_reproductive_system1.48990882
29MP0004859_abnormal_synaptic_plasticity1.45333958
30MP0002282_abnormal_trachea_morphology1.37790623
31MP0002067_abnormal_sensory_capabilities1.36987977
32MP0004233_abnormal_muscle_weight1.35673640
33MP0000678_abnormal_parathyroid_gland1.34647906
34MP0003646_muscle_fatigue1.34329651
35MP0006276_abnormal_autonomic_nervous1.33324243
36MP0003880_abnormal_central_pattern1.27519520
37MP0003635_abnormal_synaptic_transmissio1.26873797
38MP0001765_abnormal_ion_homeostasis1.25905493
39MP0002733_abnormal_thermal_nociception1.25797294
40MP0005379_endocrine/exocrine_gland_phen1.22303507
41MP0002272_abnormal_nervous_system1.20329440
42MP0000026_abnormal_inner_ear1.16790186
43MP0001970_abnormal_pain_threshold1.16322449
44MP0000955_abnormal_spinal_cord1.14918907
45MP0002184_abnormal_innervation1.14068724
46MP0002734_abnormal_mechanical_nocicepti1.10346256
47MP0004085_abnormal_heartbeat1.08502922
48MP0005395_other_phenotype1.07082722
49MP0003119_abnormal_digestive_system1.06803677
50MP0003045_fibrosis1.05408444
51MP0002064_seizures1.04738078
52MP0008058_abnormal_DNA_repair1.02160375
53MP0004142_abnormal_muscle_tone1.01465823
54MP0008004_abnormal_stomach_pH0.97842706
55MP0002557_abnormal_social/conspecific_i0.97674243
56MP0005645_abnormal_hypothalamus_physiol0.97608703
57MP0005647_abnormal_sex_gland0.93175824
58MP0000230_abnormal_systemic_arterial0.92818951
59MP0009046_muscle_twitch0.92434780
60MP0001984_abnormal_olfaction0.89685878
61MP0001664_abnormal_digestion0.88446855
62MP0002249_abnormal_larynx_morphology0.87239788
63MP0002138_abnormal_hepatobiliary_system0.86448868
64MP0004084_abnormal_cardiac_muscle0.85514181
65MP0003136_yellow_coat_color0.84135346
66MP0004510_myositis0.82450951
67MP0005167_abnormal_blood-brain_barrier0.82390649
68MP0009697_abnormal_copulation0.82152168
69MP0000049_abnormal_middle_ear0.80041080
70MP0002063_abnormal_learning/memory/cond0.78919014
71MP0003632_abnormal_nervous_system0.76954389
72MP0003638_abnormal_response/metabolism_0.76898853
73MP0005389_reproductive_system_phenotype0.73837162
74MP0002168_other_aberrant_phenotype0.71931760
75MP0003115_abnormal_respiratory_system0.71785465
76MP0008995_early_reproductive_senescence0.71555346
77MP0000538_abnormal_urinary_bladder0.71283353
78MP0005636_abnormal_mineral_homeostasis0.68255876
79MP0003878_abnormal_ear_physiology0.67999168
80MP0005377_hearing/vestibular/ear_phenot0.67999168
81MP0002127_abnormal_cardiovascular_syste0.67665652
82MP0005595_abnormal_vascular_smooth0.64835285
83MP0002882_abnormal_neuron_morphology0.63642237
84MP0002752_abnormal_somatic_nervous0.63369461
85MP0001188_hyperpigmentation0.62634557
86MP0005248_abnormal_Harderian_gland0.60397239
87MP0000470_abnormal_stomach_morphology0.59700232
88MP0002234_abnormal_pharynx_morphology0.59459115
89MP0001666_abnormal_nutrient_absorption0.57514178
90MP0005666_abnormal_adipose_tissue0.57487751
91MP0000733_abnormal_muscle_development0.57162092
92MP0003137_abnormal_impulse_conducting0.55073973
93MP0001324_abnormal_eye_pigmentation0.54592809
94MP0003011_delayed_dark_adaptation0.53738263
95MP0000358_abnormal_cell_content/0.53517990
96MP0010094_abnormal_chromosome_stability0.53380757
97MP0004036_abnormal_muscle_relaxation0.52057803
98MP0000569_abnormal_digit_pigmentation0.51017411
99MP0003329_amyloid_beta_deposits0.50825617
100MP0001764_abnormal_homeostasis0.50482421
101MP0001293_anophthalmia0.50119884
102MP0003699_abnormal_female_reproductive0.48020665
103MP0003950_abnormal_plasma_membrane0.47940662
104MP0002928_abnormal_bile_duct0.45603221
105MP0002269_muscular_atrophy0.45278814
106MP0005551_abnormal_eye_electrophysiolog0.42416634
107MP0002102_abnormal_ear_morphology0.40599861
108MP0009115_abnormal_fat_cell0.40490887
109MP0002971_abnormal_brown_adipose0.39755545
110MP0006036_abnormal_mitochondrial_physio0.39510848
111MP0005253_abnormal_eye_physiology0.39087023
112MP0002736_abnormal_nociception_after0.38682609
113MP0003633_abnormal_nervous_system0.34762525
114MP0001545_abnormal_hematopoietic_system0.33981718
115MP0005397_hematopoietic_system_phenotyp0.33981718
116MP0009278_abnormal_bone_marrow0.33279424
117MP0004019_abnormal_vitamin_homeostasis0.33149407
118MP0001119_abnormal_female_reproductive0.32224754
119MP0003111_abnormal_nucleus_morphology0.31202624
120MP0005391_vision/eye_phenotype0.30898373
121MP0000534_abnormal_ureter_morphology0.30804052
122MP0002139_abnormal_hepatobiliary_system0.30223728
123MP0004133_heterotaxia0.29135152
124MP0004811_abnormal_neuron_physiology0.28317723
125MP0006035_abnormal_mitochondrial_morpho0.28269283
126MP0000604_amyloidosis0.27635223
127MP0003631_nervous_system_phenotype0.25701628
128MP0003879_abnormal_hair_cell0.23590363
129MP0008057_abnormal_DNA_replication0.23484199
130MP0004145_abnormal_muscle_electrophysio0.23201830
131MP0003942_abnormal_urinary_system0.23014748
132MP0004742_abnormal_vestibular_system0.22223250
133MP0003861_abnormal_nervous_system0.22145421
134MP0001849_ear_inflammation0.21879765
135MP0002152_abnormal_brain_morphology0.21789485
136MP0001968_abnormal_touch/_nociception0.21238264
137MP0002169_no_abnormal_phenotype0.20395770
138MP0002873_normal_phenotype0.20167287
139MP0003948_abnormal_gas_homeostasis0.20158629
140MP0001730_embryonic_growth_arrest0.20096731
141MP0002295_abnormal_pulmonary_circulatio0.19939952
142MP0000751_myopathy0.19161921
143MP0005423_abnormal_somatic_nervous0.19023049
144MP0008569_lethality_at_weaning0.18728261
145MP0010307_abnormal_tumor_latency0.18561889
146MP0002229_neurodegeneration0.18137935
147MP0005319_abnormal_enzyme/_coenzyme0.18072230
148MP0003786_premature_aging0.17776883
149MP0002132_abnormal_respiratory_system0.17735883
150MP0008875_abnormal_xenobiotic_pharmacok0.17409972
151MP0002092_abnormal_eye_morphology0.17238359
152MP0004270_analgesia0.17211705
153MP0002693_abnormal_pancreas_physiology0.17090834
154MP0008961_abnormal_basal_metabolism0.17004278
155MP0000313_abnormal_cell_death0.16481542
156MP0005375_adipose_tissue_phenotype0.16381263
157MP0005365_abnormal_bile_salt0.16374123
158MP0001727_abnormal_embryo_implantation0.16319090
159MP0001986_abnormal_taste_sensitivity0.15300885
160MP0002118_abnormal_lipid_homeostasis0.15189868
161MP0004043_abnormal_pH_regulation0.14260237
162MP0000920_abnormal_myelination0.13960853
163MP0003959_abnormal_lean_body0.13915711
164MP0004130_abnormal_muscle_cell0.13526223

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.35900157
2Abnormal respiratory epithelium morphology (HP:0012253)9.35900157
3Abnormal respiratory motile cilium physiology (HP:0012261)9.21411570
4Abnormal ciliary motility (HP:0012262)7.43048937
5Rhinitis (HP:0012384)7.41194607
6Chronic bronchitis (HP:0004469)7.26953230
7Infertility (HP:0000789)6.66635645
8Nasal polyposis (HP:0100582)6.37252862
9Severe visual impairment (HP:0001141)5.61390467
10Abnormality of the nasal mucosa (HP:0000433)5.24383475
11Congenital sensorineural hearing impairment (HP:0008527)5.15800045
12Progressive cerebellar ataxia (HP:0002073)4.91753351
13Male infertility (HP:0003251)4.79141713
14Bronchitis (HP:0012387)4.61051582
15Bony spicule pigmentary retinopathy (HP:0007737)4.60503835
16Attenuation of retinal blood vessels (HP:0007843)4.48728217
17Bronchiectasis (HP:0002110)4.44578701
18Nephronophthisis (HP:0000090)4.25478464
19Chronic hepatic failure (HP:0100626)4.23348865
20Postural instability (HP:0002172)4.23254479
21Resting tremor (HP:0002322)4.14262577
22Cone-rod dystrophy (HP:0000548)3.89313346
23Abnormality of macular pigmentation (HP:0008002)3.79223518
24Abnormality of dental color (HP:0011073)3.66648847
25Unilateral renal agenesis (HP:0000122)3.65514140
26Genetic anticipation (HP:0003743)3.59652831
27Abnormal spermatogenesis (HP:0008669)3.58189441
28Recurrent sinusitis (HP:0011108)3.40726413
29Recurrent otitis media (HP:0000403)3.32166400
30Retinal dysplasia (HP:0007973)3.30845104
31Abnormality of the renal medulla (HP:0100957)3.21876991
32Enlarged epiphyses (HP:0010580)3.19968731
33Tubulointerstitial nephritis (HP:0001970)3.10380077
34Renovascular hypertension (HP:0100817)2.99556474
35Hyperkalemia (HP:0002153)2.96633331
36Hypoplastic ischia (HP:0003175)2.96495692
37Upper limb muscle weakness (HP:0003484)2.91170740
38Abnormal rod and cone electroretinograms (HP:0008323)2.90152368
39Recurrent bronchitis (HP:0002837)2.83783817
40Facial shape deformation (HP:0011334)2.78966408
41Potter facies (HP:0002009)2.78966408
42Peripheral hypomyelination (HP:0007182)2.68570930
43Abnormality of the ischium (HP:0003174)2.67697993
44Molar tooth sign on MRI (HP:0002419)2.63217496
45Abnormality of midbrain morphology (HP:0002418)2.63217496
46Tubular atrophy (HP:0000092)2.62995657
47Atonic seizures (HP:0010819)2.61442218
48Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.58087134
49Abnormality of the costochondral junction (HP:0000919)2.55108344
50Aplasia/Hypoplasia of the earlobes (HP:0009906)2.53734942
51Myokymia (HP:0002411)2.53196190
52Medial flaring of the eyebrow (HP:0010747)2.52289626
53Impulsivity (HP:0100710)2.48825613
54Tubulointerstitial abnormality (HP:0001969)2.45904259
55Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.31188929
56Abnormal gallbladder physiology (HP:0012438)2.30145329
57Cholecystitis (HP:0001082)2.30145329
58Abnormality of binocular vision (HP:0011514)2.27897350
59Diplopia (HP:0000651)2.27897350
60Gonadotropin excess (HP:0000837)2.25783893
61Stereotypic behavior (HP:0000733)2.24567142
62Polyuria (HP:0000103)2.23533189
63Azoospermia (HP:0000027)2.23462985
64Ulnar claw (HP:0001178)2.22192021
65Abnormality of the columella (HP:0009929)2.20081104
66Amelogenesis imperfecta (HP:0000705)2.15576808
67Hypoalphalipoproteinemia (HP:0003233)2.13695653
68Dynein arm defect of respiratory motile cilia (HP:0012255)13.6564463
69Absent/shortened dynein arms (HP:0200106)13.6564463
70Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.0441859
71Dyschromatopsia (HP:0007641)1.99715650
72Reduced antithrombin III activity (HP:0001976)1.98574208
73Portal hypertension (HP:0001409)1.97626526
74Insulin-resistant diabetes mellitus (HP:0000831)1.96810930
75Abnormality of the diencephalon (HP:0010662)1.95170244
76Bradycardia (HP:0001662)1.94038463
77Abnormality of potassium homeostasis (HP:0011042)1.92926095
78Widely patent fontanelles and sutures (HP:0004492)1.89065785
79Postaxial foot polydactyly (HP:0001830)1.87279681
80Spastic tetraparesis (HP:0001285)1.87033297
81Pancreatic cysts (HP:0001737)1.86337181
82Asymmetric septal hypertrophy (HP:0001670)1.86217813
83Febrile seizures (HP:0002373)1.86182765
84Abnormality of the hepatic vasculature (HP:0006707)1.83282021
85Tubulointerstitial fibrosis (HP:0005576)1.82826705
86Hypoplasia of the thymus (HP:0000778)1.82615431
87Stage 5 chronic kidney disease (HP:0003774)1.81670080
88Epiphyseal dysplasia (HP:0002656)1.81239866
89Protruding tongue (HP:0010808)1.80348369
90Decreased central vision (HP:0007663)1.79782593
91Heterotopia (HP:0002282)1.78955300
92Bradykinesia (HP:0002067)1.76902310
93Segmental peripheral demyelination/remyelination (HP:0003481)1.76781589
94Progressive sensorineural hearing impairment (HP:0000408)1.76532279
95Limb dystonia (HP:0002451)1.76084048
96Failure to thrive in infancy (HP:0001531)1.74475511
97Gaze-evoked nystagmus (HP:0000640)1.73426450
98Sclerocornea (HP:0000647)1.73070730
99Choroideremia (HP:0001139)1.72098120
100Polydipsia (HP:0001959)1.71130529
101Abnormal drinking behavior (HP:0030082)1.71130529
102Congenital hepatic fibrosis (HP:0002612)1.70277603
103Menstrual irregularities (HP:0000858)1.69890781
104Intellectual disability, moderate (HP:0002342)1.69860010
105Type I diabetes mellitus (HP:0100651)1.68702613
106Abnormality of the renal cortex (HP:0011035)1.68683590
107Abnormal biliary tract physiology (HP:0012439)1.67675392
108Bile duct proliferation (HP:0001408)1.67675392
109Bell-shaped thorax (HP:0001591)1.66180154
110Abnormality of renal excretion (HP:0011036)1.64175081
111Inability to walk (HP:0002540)1.63555005
112Congenital stationary night blindness (HP:0007642)1.63328899
113Macular degeneration (HP:0000608)1.62769692
114Hypergonadotropic hypogonadism (HP:0000815)1.61877137
115Osteomalacia (HP:0002749)1.61543583
116Abnormality of the dental root (HP:0006486)1.61327748
117Taurodontia (HP:0000679)1.61327748
118Abnormality of permanent molar morphology (HP:0011071)1.61327748
119Abnormality of the lower motor neuron (HP:0002366)1.61282715
120Type II diabetes mellitus (HP:0005978)1.61278432
121Short ribs (HP:0000773)1.58848811
122Oculomotor apraxia (HP:0000657)1.58740548
123Bundle branch block (HP:0011710)1.55621580
124Hemorrhage of the eye (HP:0011885)1.52015040
125Abnormality of molar (HP:0011077)1.50301360
126Abnormality of molar morphology (HP:0011070)1.50301360
127Chronic sinusitis (HP:0011109)1.48273637
128Abnormality of the dental pulp (HP:0006479)1.48134344
129Postaxial hand polydactyly (HP:0001162)1.45788928
130Hypoplasia of the capital femoral epiphysis (HP:0003090)1.45767813
131Fibular hypoplasia (HP:0003038)1.44464715
132Abnormality of dentin (HP:0010299)1.42583033
133Aplasia/Hypoplasia of the lens (HP:0008063)1.39197270
134Cystic liver disease (HP:0006706)1.38762876
135Gait imbalance (HP:0002141)1.37981089
136Congenital primary aphakia (HP:0007707)1.37875060
137Neurofibrillary tangles (HP:0002185)1.36964115
138Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.36794267
139Constricted visual fields (HP:0001133)1.35653898
140Renal dysplasia (HP:0000110)1.35208319
141Abnormality of saccadic eye movements (HP:0000570)1.33394395
142Pancreatic fibrosis (HP:0100732)1.33174936
143Decreased electroretinogram (ERG) amplitude (HP:0000654)1.31485899
144Amyotrophic lateral sclerosis (HP:0007354)1.29311228
145Facial cleft (HP:0002006)1.29129820
146Abnormal urine output (HP:0012590)1.28929784
147Microglossia (HP:0000171)1.27564397
148Optic nerve hypoplasia (HP:0000609)1.27541473
149Abnormality of ocular smooth pursuit (HP:0000617)1.27441900
150Absent frontal sinuses (HP:0002688)1.26657939
151Congenital malformation of the right heart (HP:0011723)1.25231297
152Double outlet right ventricle (HP:0001719)1.25231297
153Deformed sella turcica (HP:0002681)1.24306444
154Aplasia/Hypoplasia of the tongue (HP:0010295)1.24165105
155Supernumerary spleens (HP:0009799)1.19896279
156Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.19104258
157Nephropathy (HP:0000112)1.18912254
158Hemiparesis (HP:0001269)1.17938189
159Short thorax (HP:0010306)1.17507207
160Cerebellar dysplasia (HP:0007033)1.16769129
161Truncal obesity (HP:0001956)1.16426254
162Vascular calcification (HP:0004934)1.16160417
163Easy fatigability (HP:0003388)1.16158000
164J-shaped sella turcica (HP:0002680)1.15487700
165Sensory axonal neuropathy (HP:0003390)1.15467697
166Nephrogenic diabetes insipidus (HP:0009806)1.15312760
167True hermaphroditism (HP:0010459)1.14814396

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK49.15526194
2PDK39.15526194
3PDK25.95647171
4INSRR5.34096090
5TESK15.12185890
6PRKD34.46066634
7DDR24.09205486
8ICK3.74693194
9FRK3.34424950
10TRIM282.66400834
11SIK22.42769738
12PLK22.42687110
13BRD42.42608407
14RPS6KA42.19502035
15PTK2B2.01975212
16PNCK1.85164363
17WNK41.81588760
18STK391.73543986
19PIK3CG1.72471572
20MAP4K21.69374235
21TAOK31.65657790
22CDK31.64957913
23MARK11.64762377
24ADRBK21.54641520
25LATS11.49691106
26STK381.45457473
27TRPM71.37967450
28DYRK1B1.32295556
29NEK21.30224329
30ERN11.24655299
31CAMK11.18889407
32MST1R1.17188089
33RPS6KA51.12542495
34PDK11.11274300
35NTRK31.09045367
36ZAK1.03339485
37BMPR1B0.82792521
38IRAK10.80085260
39CASK0.76051595
40TYRO30.75271283
41LMTK20.75028531
42DYRK30.74668430
43MAPK150.71368750
44WNK10.69925348
45CAMK1D0.69631857
46CDK70.69131718
47SGK4940.62635012
48SGK2230.62635012
49ERBB40.61388900
50CDK190.60872635
51RPS6KA20.60530004
52PASK0.58961072
53UHMK10.58591627
54MAP2K60.58429634
55PDPK10.56459165
56PRKAA20.55921440
57CCNB10.53932962
58RIPK40.53739886
59CAMK1G0.53691488
60RPS6KA60.53566969
61TNK20.51956249
62TLK10.51403170
63PRKCE0.51036740
64CAMK40.50767506
65STK30.50764327
66CHEK20.48597926
67RPS6KL10.47395510
68RPS6KC10.47395510
69EEF2K0.47158620
70TTK0.46609831
71IRAK20.46453760
72MYLK0.44656996
73CSNK1A10.43095204
74MAP3K90.40522557
75HIPK20.38862422
76PINK10.37479391
77CHEK10.36961604
78ROCK10.35364633
79GRK10.35316645
80TESK20.35002924
81PAK10.34509777
82MUSK0.34280171
83PLK40.33395890
84STK38L0.32946146
85TIE10.32625490
86SGK20.31966706
87MAPK130.30595901
88OXSR10.29781897
89MAP2K70.29137617
90MAPK10.27863997
91SGK10.27608642
92AKT30.27466092
93WEE10.27244275
94NTRK20.26989393
95PRKCG0.25959190
96PAK20.24870832
97ATM0.24453510
98DYRK20.24401725
99MTOR0.23702263
100CDC70.23289290
101KIT0.20691301
102CAMK2G0.20685834
103NEK60.20674264
104ATR0.19729779
105MARK20.18598629
106MAP3K100.18479186
107MAPKAPK50.18149378
108CAMKK10.17195942
109BRSK20.16590349
110PRKAA10.16466374
111CDC42BPA0.15377592
112PRKCZ0.14662327
113AKT10.14224219
114PAK40.12663024
115RPS6KB10.12496557
116PLK10.11065702
117PRKCQ0.09152074
118CDK120.08981543
119PRKG20.08743525
120CDK150.08517720
121CDK180.06279790
122PKN10.06203278
123GSK3B0.06167585
124MARK30.05737624
125BRSK10.05101553
126CDK11A0.05078579
127CSNK2A10.04457260
128WNK30.03756162
129CDK60.03490874
130RPS6KA10.03474512
131PRKG10.03426652
132CSNK1D0.03397905
133CDK140.03158330
134CDK20.03094600
135PRKACG0.02558999
136CSNK2A20.02455822
137YES10.02421558
138CAMK2A0.02380101
139CDK10.02088403
140MAP3K50.02008794
141MAPK80.01686243
142ZAP700.01429530
143STK110.00950246
144PRKCB0.00937111
145PRKACB0.00028162
146PDGFRB-0.0258519
147RIPK1-0.0254855
148MAPK10-0.0250546
149PIM1-0.0237844
150MAP3K4-0.0202631
151PAK6-0.0197957
152CDK4-0.0176255
153GSK3A-0.0161054
154EGFR-0.0114385
155EPHB1-0.0112200
156PRKCA-0.0108552
157RPS6KA3-0.0077350
158PRKCD-0.0044750
159STK10-0.0044072

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.58386872
2Fatty acid biosynthesis_Homo sapiens_hsa000614.12917588
3Olfactory transduction_Homo sapiens_hsa047403.62541977
4Pyruvate metabolism_Homo sapiens_hsa006203.60443272
5Vitamin B6 metabolism_Homo sapiens_hsa007503.46471345
6Nicotine addiction_Homo sapiens_hsa050333.10515340
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.09639448
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.88152692
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.86529221
10Linoleic acid metabolism_Homo sapiens_hsa005912.79975743
11Propanoate metabolism_Homo sapiens_hsa006402.63484587
12Glucagon signaling pathway_Homo sapiens_hsa049222.56294064
13Carbohydrate digestion and absorption_Homo sapiens_hsa049732.38519106
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.32310596
15Basal transcription factors_Homo sapiens_hsa030222.14798081
16Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.03275736
17Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.99498874
18Glycerolipid metabolism_Homo sapiens_hsa005611.98493827
19Selenocompound metabolism_Homo sapiens_hsa004501.97587506
20Glycosaminoglycan degradation_Homo sapiens_hsa005311.94179789
21Butanoate metabolism_Homo sapiens_hsa006501.93581434
22Morphine addiction_Homo sapiens_hsa050321.91442177
23Primary bile acid biosynthesis_Homo sapiens_hsa001201.86632699
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.84949386
25Oocyte meiosis_Homo sapiens_hsa041141.84644824
26PPAR signaling pathway_Homo sapiens_hsa033201.78264156
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.75506740
28Dorso-ventral axis formation_Homo sapiens_hsa043201.71974003
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69927359
30Glycerophospholipid metabolism_Homo sapiens_hsa005641.67741623
31Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.67027722
32Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.64841626
33Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.62858208
34Mineral absorption_Homo sapiens_hsa049781.55993799
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.55591568
36Pentose phosphate pathway_Homo sapiens_hsa000301.55558402
37Fructose and mannose metabolism_Homo sapiens_hsa000511.54267341
38GABAergic synapse_Homo sapiens_hsa047271.50255891
39Serotonergic synapse_Homo sapiens_hsa047261.49638944
40Carbon metabolism_Homo sapiens_hsa012001.44686607
41Nitrogen metabolism_Homo sapiens_hsa009101.37915092
42Amphetamine addiction_Homo sapiens_hsa050311.35413778
43Ether lipid metabolism_Homo sapiens_hsa005651.34082440
44Aldosterone synthesis and secretion_Homo sapiens_hsa049251.33444960
45Maturity onset diabetes of the young_Homo sapiens_hsa049501.31985172
46Cardiac muscle contraction_Homo sapiens_hsa042601.31436392
47Fat digestion and absorption_Homo sapiens_hsa049751.30736785
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26864505
49Fatty acid metabolism_Homo sapiens_hsa012121.25915816
50Fatty acid degradation_Homo sapiens_hsa000711.25370682
51Fanconi anemia pathway_Homo sapiens_hsa034601.24308135
52Antigen processing and presentation_Homo sapiens_hsa046121.21908202
53Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.14803596
54Cholinergic synapse_Homo sapiens_hsa047251.11619196
55Phototransduction_Homo sapiens_hsa047441.10513251
56Huntingtons disease_Homo sapiens_hsa050161.08465760
57Gap junction_Homo sapiens_hsa045401.08233148
58Renin secretion_Homo sapiens_hsa049241.06790868
59Cysteine and methionine metabolism_Homo sapiens_hsa002701.03136410
60mRNA surveillance pathway_Homo sapiens_hsa030151.01408164
61Purine metabolism_Homo sapiens_hsa002300.99794850
62Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.96608401
63Glutathione metabolism_Homo sapiens_hsa004800.91113434
64Collecting duct acid secretion_Homo sapiens_hsa049660.89415777
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89159426
66Biosynthesis of amino acids_Homo sapiens_hsa012300.87948497
67Bile secretion_Homo sapiens_hsa049760.87295089
68RNA transport_Homo sapiens_hsa030130.85913137
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.83770544
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83297564
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.82370135
72Insulin secretion_Homo sapiens_hsa049110.81498335
73Oxytocin signaling pathway_Homo sapiens_hsa049210.81176917
74Retinol metabolism_Homo sapiens_hsa008300.80779727
75ECM-receptor interaction_Homo sapiens_hsa045120.77201261
76Thyroid hormone synthesis_Homo sapiens_hsa049180.75359315
77Chemical carcinogenesis_Homo sapiens_hsa052040.74999640
78Hedgehog signaling pathway_Homo sapiens_hsa043400.74877449
79Sulfur relay system_Homo sapiens_hsa041220.74069158
80Adipocytokine signaling pathway_Homo sapiens_hsa049200.73867615
81Estrogen signaling pathway_Homo sapiens_hsa049150.73548558
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.70252716
83Inositol phosphate metabolism_Homo sapiens_hsa005620.68863973
84Tryptophan metabolism_Homo sapiens_hsa003800.67589639
85Legionellosis_Homo sapiens_hsa051340.67202487
86Arginine biosynthesis_Homo sapiens_hsa002200.66132706
87Arachidonic acid metabolism_Homo sapiens_hsa005900.65382326
88Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64669813
89Long-term potentiation_Homo sapiens_hsa047200.64273542
90Renin-angiotensin system_Homo sapiens_hsa046140.62315513
91cGMP-PKG signaling pathway_Homo sapiens_hsa040220.61633963
92Graft-versus-host disease_Homo sapiens_hsa053320.59675017
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.59429193
94Calcium signaling pathway_Homo sapiens_hsa040200.59087238
95Protein digestion and absorption_Homo sapiens_hsa049740.58911351
96Pancreatic secretion_Homo sapiens_hsa049720.56284312
97Salivary secretion_Homo sapiens_hsa049700.56148198
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.56068426
99Systemic lupus erythematosus_Homo sapiens_hsa053220.55204685
100ABC transporters_Homo sapiens_hsa020100.55060464
101Phospholipase D signaling pathway_Homo sapiens_hsa040720.54709425
102Synaptic vesicle cycle_Homo sapiens_hsa047210.52288667
103Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.52097232
104Gastric acid secretion_Homo sapiens_hsa049710.51209276
105Endocytosis_Homo sapiens_hsa041440.49550060
106Sulfur metabolism_Homo sapiens_hsa009200.48885335
107beta-Alanine metabolism_Homo sapiens_hsa004100.48882385
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47612753
109MAPK signaling pathway_Homo sapiens_hsa040100.47360081
110Lysine degradation_Homo sapiens_hsa003100.46800204
111Arginine and proline metabolism_Homo sapiens_hsa003300.46332890
112Transcriptional misregulation in cancer_Homo sapiens_hsa052020.45321214
113Taste transduction_Homo sapiens_hsa047420.45063562
114Type I diabetes mellitus_Homo sapiens_hsa049400.45019450
115AMPK signaling pathway_Homo sapiens_hsa041520.42966930
116Long-term depression_Homo sapiens_hsa047300.41052132
117Circadian entrainment_Homo sapiens_hsa047130.40674415
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40467361
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40346477
120Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.38962432
121Autoimmune thyroid disease_Homo sapiens_hsa053200.38085233
122Metabolic pathways_Homo sapiens_hsa011000.37937746
123Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.37570900
124Dopaminergic synapse_Homo sapiens_hsa047280.37271976
125Allograft rejection_Homo sapiens_hsa053300.35308831
126Vascular smooth muscle contraction_Homo sapiens_hsa042700.34615538
127cAMP signaling pathway_Homo sapiens_hsa040240.34590326
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.30821124
129Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.30546737
130Platelet activation_Homo sapiens_hsa046110.29795867
131Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28840491
132Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.28564040
133VEGF signaling pathway_Homo sapiens_hsa043700.25616781
134Alcoholism_Homo sapiens_hsa050340.21021114
135Pyrimidine metabolism_Homo sapiens_hsa002400.17220559
136Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.16501765
137Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.14878742
138HIF-1 signaling pathway_Homo sapiens_hsa040660.12671966
139Cocaine addiction_Homo sapiens_hsa050300.12426731
140Salmonella infection_Homo sapiens_hsa051320.08043993
141Wnt signaling pathway_Homo sapiens_hsa043100.07145067
142N-Glycan biosynthesis_Homo sapiens_hsa005100.05013040
143Basal cell carcinoma_Homo sapiens_hsa052170.04097734
144Glutamatergic synapse_Homo sapiens_hsa047240.04094574
145Type II diabetes mellitus_Homo sapiens_hsa049300.02836184

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