CCER2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hair cell differentiation (GO:0035315)9.16072966
2inner ear receptor cell differentiation (GO:0060113)8.80165319
3pentose metabolic process (GO:0019321)8.67599416
4synaptic vesicle exocytosis (GO:0016079)7.41809945
5behavioral response to nicotine (GO:0035095)7.14845966
6mechanoreceptor differentiation (GO:0042490)7.12950906
7diterpenoid biosynthetic process (GO:0016102)6.93409210
8righting reflex (GO:0060013)6.86728497
9pyrimidine nucleobase catabolic process (GO:0006208)6.83060900
10layer formation in cerebral cortex (GO:0021819)6.02437598
11cell migration in hindbrain (GO:0021535)5.96127303
12sensory perception of sound (GO:0007605)5.92383663
13inner ear morphogenesis (GO:0042472)5.89888199
14sensory perception of mechanical stimulus (GO:0050954)5.86392786
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.66060783
16substrate-independent telencephalic tangential migration (GO:0021826)5.49035739
17substrate-independent telencephalic tangential interneuron migration (GO:0021843)5.49035739
18neuron recognition (GO:0008038)5.37693157
19nucleobase catabolic process (GO:0046113)5.29368389
20face development (GO:0060324)5.29193486
21terpenoid biosynthetic process (GO:0016114)4.88116226
22regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.79599772
23endocardial cushion morphogenesis (GO:0003203)4.78971989
24establishment of mitochondrion localization (GO:0051654)4.77332766
25adult walking behavior (GO:0007628)4.67087384
26cranial nerve development (GO:0021545)4.64713367
27establishment of skin barrier (GO:0061436)4.63935757
28regulation of synapse structural plasticity (GO:0051823)4.58442814
29regulation of water loss via skin (GO:0033561)4.54015888
30positive regulation of protein homooligomerization (GO:0032464)4.37096075
31calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.31678091
32mitochondrion transport along microtubule (GO:0047497)4.31472349
33establishment of mitochondrion localization, microtubule-mediated (GO:0034643)4.31472349
34regulation of secondary heart field cardioblast proliferation (GO:0003266)4.31238901
35regulation of cardioblast proliferation (GO:0003264)4.31238901
36lateral sprouting from an epithelium (GO:0060601)4.29076625
37retinal metabolic process (GO:0042574)4.28530054
38neuronal ion channel clustering (GO:0045161)4.27132473
39axonal fasciculation (GO:0007413)4.26225040
40presynaptic membrane organization (GO:0097090)4.25097666
41adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)4.23430497
42cornea development in camera-type eye (GO:0061303)4.23059422
43spinal cord motor neuron differentiation (GO:0021522)4.18092132
44detection of mechanical stimulus (GO:0050982)4.15926035
45retinal ganglion cell axon guidance (GO:0031290)4.08950765
46bone trabecula formation (GO:0060346)4.06410862
47neuromuscular process controlling balance (GO:0050885)4.04582310
48planar cell polarity pathway involved in neural tube closure (GO:0090179)4.02075858
49mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.92467801
50positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.92467801
51response to pheromone (GO:0019236)3.87803886
52mesenchyme morphogenesis (GO:0072132)3.85636062
53aorta morphogenesis (GO:0035909)3.81915740
54central nervous system myelination (GO:0022010)3.78380115
55axon ensheathment in central nervous system (GO:0032291)3.78380115
56cell differentiation in spinal cord (GO:0021515)3.77081906
57detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.75900211
58mechanosensory behavior (GO:0007638)3.69679235
59regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.68623842
60positive regulation of filopodium assembly (GO:0051491)3.63639523
61protein polyglutamylation (GO:0018095)3.61816912
62embryonic eye morphogenesis (GO:0048048)3.57594702
63outer ear morphogenesis (GO:0042473)3.56399212
64synapse assembly (GO:0007416)3.54941011
65collecting duct development (GO:0072044)3.52690404
66ear development (GO:0043583)3.52064655
67regulation of dopamine secretion (GO:0014059)3.50382731
68response to gravity (GO:0009629)3.49115101
69reflex (GO:0060004)3.48745544
70regulation of action potential (GO:0098900)3.45470533
71regulation of glutamate receptor signaling pathway (GO:1900449)3.44816408
72positive regulation of dendritic spine morphogenesis (GO:0061003)3.42829927
73post-embryonic morphogenesis (GO:0009886)3.42689904
74neuronal action potential propagation (GO:0019227)3.41481309
75keratinization (GO:0031424)3.40086769
76seminiferous tubule development (GO:0072520)3.39294699
77cranial nerve morphogenesis (GO:0021602)3.38679653
78auditory behavior (GO:0031223)3.37935415
79regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.37174414
80morphogenesis of embryonic epithelium (GO:0016331)3.36599688
81epidermal cell differentiation (GO:0009913)3.33665978
82neuromuscular process controlling posture (GO:0050884)3.31606554
83nerve development (GO:0021675)3.30712817
84neuron migration (GO:0001764)3.26241896
85positive regulation of gastrulation (GO:2000543)3.25546106
86synaptic transmission, cholinergic (GO:0007271)3.22886624
87limb bud formation (GO:0060174)3.22456672
88negative regulation of cytosolic calcium ion concentration (GO:0051481)3.21491843
89ionotropic glutamate receptor signaling pathway (GO:0035235)3.15866481
90regulation of transforming growth factor beta2 production (GO:0032909)3.15132036
91cerebral cortex radially oriented cell migration (GO:0021799)3.13779869
92axon extension (GO:0048675)3.13305619
93regulation of chromatin binding (GO:0035561)3.13049148
94metanephric mesenchyme development (GO:0072075)3.12702590
95cochlea development (GO:0090102)3.10352672
96peristalsis (GO:0030432)3.09803642
97dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.05205300
98dendritic spine morphogenesis (GO:0060997)3.04509060
99neurofilament cytoskeleton organization (GO:0060052)3.03074660
100synaptic vesicle maturation (GO:0016188)3.02627740
101postsynaptic membrane organization (GO:0001941)3.02402703
102cytoskeletal anchoring at plasma membrane (GO:0007016)3.00943525
103dopamine receptor signaling pathway (GO:0007212)2.99961322
104regulation of microtubule-based movement (GO:0060632)2.98224255
105regulation of chemokine-mediated signaling pathway (GO:0070099)2.95478922
106regulation of heart morphogenesis (GO:2000826)2.94731301
107generation of neurons (GO:0048699)2.94486693
108glutamate secretion (GO:0014047)2.94379674
109cochlea morphogenesis (GO:0090103)2.94101013
110regulation of calcium ion-dependent exocytosis (GO:0017158)2.91379112
111transmission of nerve impulse (GO:0019226)2.89682213
112regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.89531239
113kidney mesenchyme development (GO:0072074)2.88085896
114nephron tubule formation (GO:0072079)2.88017866
115glial cell proliferation (GO:0014009)2.86498555
116establishment of tissue polarity (GO:0007164)2.85738065
117establishment of planar polarity (GO:0001736)2.85738065
118positive regulation of dendritic spine development (GO:0060999)2.85689951
119cerebellar Purkinje cell differentiation (GO:0021702)2.83961060
120neuron projection extension (GO:1990138)2.83089287
121non-canonical Wnt signaling pathway (GO:0035567)2.82893432
122multicellular organismal water homeostasis (GO:0050891)2.81066864
123regulation of filopodium assembly (GO:0051489)2.80514764
124synaptic transmission, glutamatergic (GO:0035249)2.80033018
125negative regulation of mast cell activation (GO:0033004)2.78590055
126synaptic transmission, dopaminergic (GO:0001963)2.78405441
127calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.77757445
128RNA localization (GO:0006403)2.77747683
129desmosome organization (GO:0002934)2.75430955
130prepulse inhibition (GO:0060134)2.74826825
131Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.74396817
132neuromuscular synaptic transmission (GO:0007274)2.74000232
133positive regulation of synapse assembly (GO:0051965)2.73576767
134synapse organization (GO:0050808)2.73121947
135response to misfolded protein (GO:0051788)2.72403069
136cell proliferation in forebrain (GO:0021846)2.71282401
137hemidesmosome assembly (GO:0031581)2.67360033
138neuron cell-cell adhesion (GO:0007158)2.67141354
139phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.65631368
140lung epithelium development (GO:0060428)2.65131403
141epithelial cilium movement (GO:0003351)2.65079452
142neuromuscular process (GO:0050905)2.65041415
143multicellular organismal signaling (GO:0035637)2.64787944
144neuron fate commitment (GO:0048663)2.64430016
145cell differentiation involved in metanephros development (GO:0072202)2.63452186
146regulation of respiratory system process (GO:0044065)2.61852169
147inner ear receptor cell development (GO:0060119)2.61681241
148spinal cord association neuron differentiation (GO:0021527)2.61654252
149retinoic acid metabolic process (GO:0042573)2.61475003
150regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.60014787
151regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.59966581
152regulation of establishment of planar polarity (GO:0090175)2.59585983
153regulation of protein homooligomerization (GO:0032462)2.58673064
154vocalization behavior (GO:0071625)2.58634214
155urogenital system development (GO:0001655)2.58509721
156metanephric nephron tubule development (GO:0072234)2.58108577
157metanephric tubule development (GO:0072170)2.58108577
158dendrite morphogenesis (GO:0048813)2.57660414
159neuron-neuron synaptic transmission (GO:0007270)2.57145408
160dorsal/ventral axis specification (GO:0009950)2.56739154
161inner ear receptor stereocilium organization (GO:0060122)2.56427001
162exploration behavior (GO:0035640)2.55400024
163positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.54797296
164digestive tract morphogenesis (GO:0048546)2.54287956
165regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.54217664
166regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.54217664
167regulation of cilium movement (GO:0003352)2.54128035
168establishment of synaptic vesicle localization (GO:0097480)2.53946251
169synaptic vesicle transport (GO:0048489)2.53946251
170middle ear morphogenesis (GO:0042474)2.53421100
171forebrain neuron differentiation (GO:0021879)2.53313929
172atrioventricular valve morphogenesis (GO:0003181)2.51797943
173negative regulation of cell fate specification (GO:0009996)2.50860905
174skin morphogenesis (GO:0043589)2.49175293
175cardiac muscle cell proliferation (GO:0060038)2.47643975
176detection of mechanical stimulus involved in sensory perception (GO:0050974)2.46952072
177growth hormone receptor signaling pathway (GO:0060396)2.43561783
178citrulline biosynthetic process (GO:0019240)2.43513366
179apical protein localization (GO:0045176)2.36817427
180negative regulation of leukocyte chemotaxis (GO:0002689)2.36556919
181outflow tract septum morphogenesis (GO:0003148)2.36368162
182regulation of hair follicle development (GO:0051797)2.34450586
183tight junction assembly (GO:0070830)2.33516783
184negative regulation of smooth muscle cell migration (GO:0014912)2.32316641
185eye morphogenesis (GO:0048592)2.31914634
186heart valve morphogenesis (GO:0003179)2.31097162
187pharyngeal system development (GO:0060037)2.31088455
188cellular response to prostaglandin stimulus (GO:0071379)2.30074480
189response to inactivity (GO:0014854)2.29120749
190regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.28291535
191epithelial cell fate commitment (GO:0072148)2.28067070
192positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.24745908
193ectodermal placode formation (GO:0060788)2.23905496
194developmental cell growth (GO:0048588)2.23785690
195auditory receptor cell differentiation (GO:0042491)14.1846321

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.00188398
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.96608768
3EZH2_22144423_ChIP-Seq_EOC_Human3.14087705
4DROSHA_22980978_ChIP-Seq_HELA_Human2.91682262
5CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.69412263
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.39812909
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.39812909
8REST_18959480_ChIP-ChIP_MESCs_Mouse2.34220913
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.34180786
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.23493648
11SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16016431
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.15695536
13EZH2_27294783_Chip-Seq_ESCs_Mouse2.15371960
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.15015274
15ZNF217_24962896_ChIP-Seq_MCF-7_Human2.11544405
16SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.08154678
17CBX2_27304074_Chip-Seq_ESCs_Mouse2.07515597
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.04666940
19TRIM28_21343339_ChIP-Seq_HEK293_Human2.01203871
20SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.00332720
21SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.98046645
22MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.96611410
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.95761329
24EZH2_27304074_Chip-Seq_ESCs_Mouse1.93858546
25CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.84153959
26MTF2_20144788_ChIP-Seq_MESCs_Mouse1.83326840
27EED_16625203_ChIP-ChIP_MESCs_Mouse1.82193576
28ERG_21242973_ChIP-ChIP_JURKAT_Human1.81259818
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79192959
30TP53_18474530_ChIP-ChIP_U2OS_Human1.79003031
31WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.78963152
32AR_21572438_ChIP-Seq_LNCaP_Human1.77046306
33RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.71943174
34DNAJC2_21179169_ChIP-ChIP_NT2_Human1.68784925
35ZNF263_19887448_ChIP-Seq_K562_Human1.64655125
36VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.64162937
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.60734034
38PKCTHETA_26484144_Chip-Seq_BREAST_Human1.58592435
39KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.58303040
40KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.58303040
41KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.58303040
42TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.57773262
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57735766
44RBPJ_22232070_ChIP-Seq_NCS_Mouse1.57540295
45RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.57273080
46WT1_25993318_ChIP-Seq_PODOCYTE_Human1.55876380
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.54278913
48RNF2_27304074_Chip-Seq_NSC_Mouse1.53813072
49AHR_22903824_ChIP-Seq_MCF-7_Human1.52268915
50CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.50985795
51TP63_19390658_ChIP-ChIP_HaCaT_Human1.50894479
52RING1B_27294783_Chip-Seq_ESCs_Mouse1.49839972
53ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.47310138
54VDR_24787735_ChIP-Seq_THP-1_Human1.47081528
55ARNT_22903824_ChIP-Seq_MCF-7_Human1.46616819
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.44996134
57CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.44337489
58KDM2B_26808549_Chip-Seq_K562_Human1.44162803
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.42895584
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.42769893
61EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.42609222
62RING1B_27294783_Chip-Seq_NPCs_Mouse1.39358959
63RXR_22108803_ChIP-Seq_LS180_Human1.39100561
64PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.36031605
65CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30661396
66CTCF_27219007_Chip-Seq_Bcells_Human1.30458657
67GATA1_26923725_Chip-Seq_HPCs_Mouse1.27214844
68KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22702478
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.21521805
70CTBP2_25329375_ChIP-Seq_LNCAP_Human1.19460049
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18394606
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18394606
73ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.18371294
74RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.16677028
75ZNF274_21170338_ChIP-Seq_K562_Hela1.15932911
76REST_21632747_ChIP-Seq_MESCs_Mouse1.15670574
77SOX9_24532713_ChIP-Seq_HFSC_Mouse1.14343987
78YY1_22570637_ChIP-Seq_MALME-3M_Human1.13441288
79SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.12193856
80TP53_20018659_ChIP-ChIP_R1E_Mouse1.11158925
81PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.09462276
82VDR_22108803_ChIP-Seq_LS180_Human1.08905387
83ZFP281_27345836_Chip-Seq_ESCs_Mouse1.08311897
84KDM2B_26808549_Chip-Seq_JURKAT_Human1.08087883
85ERA_21632823_ChIP-Seq_H3396_Human1.07466303
86SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.07462694
87RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.06742680
88SMAD3_21741376_ChIP-Seq_ESCs_Human1.06702020
89NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.06004805
90WDR5_24793694_ChIP-Seq_LNCAP_Human1.05848465
91KDM2B_26808549_Chip-Seq_DND41_Human1.04702963
92EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.04356524
93BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.04134889
94PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.04001730
95KLF4_19829295_ChIP-Seq_ESCs_Human1.03680063
96RARG_19884340_ChIP-ChIP_MEFs_Mouse1.03524819
97NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.02628003
98NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.02459034
99DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.00506176
100IGF1R_20145208_ChIP-Seq_DFB_Human1.00467171
101SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99932110
102STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.99813838
103SMAD3_21741376_ChIP-Seq_EPCs_Human0.98888218
104IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98405911
105EP300_21415370_ChIP-Seq_HL-1_Mouse0.98051606
106ETV2_25802403_ChIP-Seq_MESCs_Mouse0.97467468
107EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96481230
108AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.96324554
109FOXO3_23340844_ChIP-Seq_DLD1_Human0.96303616
110RARB_27405468_Chip-Seq_BRAIN_Mouse0.95427360
111TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95180917
112OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.94896528
113CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94777957
114OCT4_19829295_ChIP-Seq_ESCs_Human0.94115627
115P68_20966046_ChIP-Seq_HELA_Human0.93845885
116WT1_19549856_ChIP-ChIP_CCG9911_Human0.92873595
117ELF1_20517297_ChIP-Seq_JURKAT_Human0.92526709
118GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92357548
119TP53_22573176_ChIP-Seq_HFKS_Human0.92310940
120TP53_22127205_ChIP-Seq_IMR90_Human0.91967543
121TAF2_19829295_ChIP-Seq_ESCs_Human0.91791600
122CTCF_20526341_ChIP-Seq_ESCs_Human0.91747932
123P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91647072
124SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.91299048
125HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.90863749
126ISL1_27105846_Chip-Seq_CPCs_Mouse0.90394754
127RACK7_27058665_Chip-Seq_MCF-7_Human0.89046683
128SMAD4_21799915_ChIP-Seq_A2780_Human0.88455107
129ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.88057066
130BCL6_27268052_Chip-Seq_Bcells_Human0.87819798
131BMI1_23680149_ChIP-Seq_NPCS_Mouse0.87251286
132TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.86200219
133RUNX1_27514584_Chip-Seq_MCF-7_Human0.86028759
134CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.85854987
135TCF4_22108803_ChIP-Seq_LS180_Human0.85851458
136GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85843903
137SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.85207199
138E2F1_20622854_ChIP-Seq_HELA_Human0.85076770
139FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.84842876
140SMC4_20622854_ChIP-Seq_HELA_Human0.84175369
141MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.83970426
142KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.83795442
143LXR_22292898_ChIP-Seq_THP-1_Human0.83789655
144RAC3_21632823_ChIP-Seq_H3396_Human0.82857099
145YAP1_20516196_ChIP-Seq_MESCs_Mouse0.82855374
146NANOG_20526341_ChIP-Seq_ESCs_Human0.82692332
147ESR1_21235772_ChIP-Seq_MCF-7_Human0.82598320
148KLF5_25053715_ChIP-Seq_YYC3_Human0.81956006
149MYC_19829295_ChIP-Seq_ESCs_Human0.81538719
150EGR1_19374776_ChIP-ChIP_THP-1_Human0.81521930
151NCOR_22424771_ChIP-Seq_293T_Human0.80746059
152PRDM14_20953172_ChIP-Seq_ESCs_Human0.79025813
153MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.78455541
154TOP2B_26459242_ChIP-Seq_MCF-7_Human0.78160933
155BCOR_27268052_Chip-Seq_Bcells_Human0.77913313
156PHF8_20622854_ChIP-Seq_HELA_Human0.77290331

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003879_abnormal_hair_cell9.13179055
2MP0001485_abnormal_pinna_reflex8.53348175
3MP0003878_abnormal_ear_physiology8.47868041
4MP0005377_hearing/vestibular/ear_phenot8.47868041
5MP0005423_abnormal_somatic_nervous5.45281102
6MP0000026_abnormal_inner_ear3.74793762
7MP0002822_catalepsy3.61733427
8MP0001486_abnormal_startle_reflex3.44743929
9MP0003787_abnormal_imprinting3.21964144
10MP0001963_abnormal_hearing_physiology3.13354225
11MP0004742_abnormal_vestibular_system3.00803197
12MP0005248_abnormal_Harderian_gland2.85392054
13MP0002638_abnormal_pupillary_reflex2.15399785
14MP0009379_abnormal_foot_pigmentation1.94068263
15MP0002163_abnormal_gland_morphology1.90245556
16MP0010234_abnormal_vibrissa_follicle1.80269236
17MP0003938_abnormal_ear_development1.79289584
18MP0000569_abnormal_digit_pigmentation1.75512125
19MP0002909_abnormal_adrenal_gland1.73653197
20MP0005394_taste/olfaction_phenotype1.73142036
21MP0005499_abnormal_olfactory_system1.73142036
22MP0008789_abnormal_olfactory_epithelium1.71018294
23MP0002876_abnormal_thyroid_physiology1.62893583
24MP0002557_abnormal_social/conspecific_i1.59315883
25MP0002734_abnormal_mechanical_nocicepti1.51047439
26MP0001188_hyperpigmentation1.50032602
27MP0006276_abnormal_autonomic_nervous1.47995778
28MP0006292_abnormal_olfactory_placode1.47439716
29MP0003136_yellow_coat_color1.46669786
30MP0002837_dystrophic_cardiac_calcinosis1.42625828
31MP0005551_abnormal_eye_electrophysiolog1.42409862
32MP0005275_abnormal_skin_tensile1.36601998
33MP0009745_abnormal_behavioral_response1.36326690
34MP0008877_abnormal_DNA_methylation1.35038569
35MP0003646_muscle_fatigue1.34918856
36MP0002160_abnormal_reproductive_system1.34222402
37MP0004130_abnormal_muscle_cell1.33127714
38MP0002796_impaired_skin_barrier1.31950356
39MP0003121_genomic_imprinting1.31889861
40MP0005670_abnormal_white_adipose1.26716516
41MP0003890_abnormal_embryonic-extraembry1.26460974
42MP0001529_abnormal_vocalization1.26246408
43MP0004142_abnormal_muscle_tone1.26239993
44MP0004147_increased_porphyrin_level1.25048445
45MP0003941_abnormal_skin_development1.23335313
46MP0004859_abnormal_synaptic_plasticity1.22823999
47MP0003705_abnormal_hypodermis_morpholog1.21863282
48MP0005646_abnormal_pituitary_gland1.21294795
49MP0001970_abnormal_pain_threshold1.19413486
50MP0002653_abnormal_ependyma_morphology1.17459023
51MP0001849_ear_inflammation1.16319101
52MP0001502_abnormal_circadian_rhythm1.14323594
53MP0010030_abnormal_orbit_morphology1.11509697
54MP0001346_abnormal_lacrimal_gland1.11118062
55MP0005379_endocrine/exocrine_gland_phen1.06138785
56MP0004145_abnormal_muscle_electrophysio1.03627591
57MP0010678_abnormal_skin_adnexa1.03395804
58MP0001984_abnormal_olfaction1.02540790
59MP0000579_abnormal_nail_morphology1.02261767
60MP0005623_abnormal_meninges_morphology1.02177816
61MP0000762_abnormal_tongue_morphology1.01993972
62MP0004811_abnormal_neuron_physiology1.01522996
63MP0002938_white_spotting0.96485988
64MP0005389_reproductive_system_phenotype0.96214465
65MP0001986_abnormal_taste_sensitivity0.94588376
66MP0004858_abnormal_nervous_system0.93484583
67MP0000383_abnormal_hair_follicle0.93105571
68MP0002152_abnormal_brain_morphology0.92945976
69MP0003011_delayed_dark_adaptation0.92310983
70MP0001919_abnormal_reproductive_system0.89565375
71MP0002735_abnormal_chemical_nociception0.89482260
72MP0002752_abnormal_somatic_nervous0.89444305
73MP0003942_abnormal_urinary_system0.88866111
74MP0000534_abnormal_ureter_morphology0.88339058
75MP0002184_abnormal_innervation0.87576871
76MP0002210_abnormal_sex_determination0.87106672
77MP0002249_abnormal_larynx_morphology0.85535206
78MP0002095_abnormal_skin_pigmentation0.84906450
79MP0005195_abnormal_posterior_eye0.84706195
80MP0002733_abnormal_thermal_nociception0.84243487
81MP0000613_abnormal_salivary_gland0.83941447
82MP0010386_abnormal_urinary_bladder0.83685516
83MP0005386_behavior/neurological_phenoty0.82929037
84MP0004924_abnormal_behavior0.82929037
85MP0004885_abnormal_endolymph0.81545489
86MP0001440_abnormal_grooming_behavior0.80136115
87MP0002233_abnormal_nose_morphology0.78654791
88MP0001905_abnormal_dopamine_level0.78498767
89MP0004272_abnormal_basement_membrane0.74950029
90MP0002229_neurodegeneration0.74347015
91MP0002882_abnormal_neuron_morphology0.73980204
92MP0006072_abnormal_retinal_apoptosis0.73799692
93MP0008995_early_reproductive_senescence0.73693352
94MP0005174_abnormal_tail_pigmentation0.72632000
95MP0003698_abnormal_male_reproductive0.71461999
96MP0004270_analgesia0.71139886
97MP0010352_gastrointestinal_tract_polyps0.68495295
98MP0005645_abnormal_hypothalamus_physiol0.67859120
99MP0005253_abnormal_eye_physiology0.67824890
100MP0001348_abnormal_lacrimal_gland0.66518589
101MP0002272_abnormal_nervous_system0.66263930
102MP0002067_abnormal_sensory_capabilities0.65603822
103MP0002254_reproductive_system_inflammat0.65380420
104MP0009046_muscle_twitch0.64926186
105MP0002060_abnormal_skin_morphology0.63844147
106MP0005501_abnormal_skin_physiology0.62473999
107MP0001968_abnormal_touch/_nociception0.62217929
108MP0001216_abnormal_epidermal_layer0.61189556
109MP0003635_abnormal_synaptic_transmissio0.60854223
110MP0005076_abnormal_cell_differentiation0.60455476
111MP0000049_abnormal_middle_ear0.59954499
112MP0008438_abnormal_cutaneous_collagen0.59473229
113MP0004133_heterotaxia0.58746909
114MP0001324_abnormal_eye_pigmentation0.58746780
115MP0001340_abnormal_eyelid_morphology0.58740870
116MP0002282_abnormal_trachea_morphology0.55996581
117MP0002098_abnormal_vibrissa_morphology0.55551599
118MP0001943_abnormal_respiration0.55332000
119MP0010771_integument_phenotype0.54136022
120MP0000467_abnormal_esophagus_morphology0.51234433
121MP0002102_abnormal_ear_morphology0.50842186
122MP0003122_maternal_imprinting0.50740305
123MP0000647_abnormal_sebaceous_gland0.48267888
124MP0002277_abnormal_respiratory_mucosa0.48148910
125MP0000377_abnormal_hair_follicle0.48024851
126MP0003755_abnormal_palate_morphology0.47797401
127MP0001243_abnormal_dermal_layer0.44748233
128MP0000631_abnormal_neuroendocrine_gland0.44068763
129MP0001299_abnormal_eye_distance/0.43730086
130MP0003566_abnormal_cell_adhesion0.42873440
131MP0003329_amyloid_beta_deposits0.41495725
132MP0000778_abnormal_nervous_system0.40487054
133MP0003880_abnormal_central_pattern0.40104860
134MP0002751_abnormal_autonomic_nervous0.39880502
135MP0000462_abnormal_digestive_system0.39062353
136MP0003115_abnormal_respiratory_system0.37093611
137MP0009250_abnormal_appendicular_skeleto0.36994792
138MP0009384_cardiac_valve_regurgitation0.36876662
139MP0002116_abnormal_craniofacial_bone0.36646338
140MP0002177_abnormal_outer_ear0.34997830
141MP0002066_abnormal_motor_capabilities/c0.34513064
142MP0004381_abnormal_hair_follicle0.33790951
143MP0009053_abnormal_anal_canal0.32422983
144MP0001286_abnormal_eye_development0.31288821
145MP0003123_paternal_imprinting0.31190881
146MP0002234_abnormal_pharynx_morphology0.31112260
147MP0002063_abnormal_learning/memory/cond0.30671299
148MP0003453_abnormal_keratinocyte_physiol0.28928352
149MP0001727_abnormal_embryo_implantation0.28849106
150MP0002089_abnormal_postnatal_growth/wei0.28649917
151MP0004134_abnormal_chest_morphology0.27615878
152MP0003935_abnormal_craniofacial_develop0.27536589
153MP0003861_abnormal_nervous_system0.27424317
154MP0000955_abnormal_spinal_cord0.27154998
155MP0002064_seizures0.26938796
156MP0008961_abnormal_basal_metabolism0.26806603
157MP0000427_abnormal_hair_cycle0.26695226
158MP0002572_abnormal_emotion/affect_behav0.26328528
159MP0000428_abnormal_craniofacial_morphol0.25676527
160MP0000751_myopathy0.25616034
161MP0001270_distended_abdomen0.24792162

Predicted human phenotypes

RankGene SetZ-score
1Lip pit (HP:0100267)5.17695602
2Myokymia (HP:0002411)4.56164613
3Congenital sensorineural hearing impairment (HP:0008527)4.55885251
4Hyperventilation (HP:0002883)4.28422799
5Milia (HP:0001056)4.21469093
6Pili torti (HP:0003777)4.17259708
7Morphological abnormality of the middle ear (HP:0008609)3.80119022
8Thoracolumbar scoliosis (HP:0002944)3.77270712
9Increased IgE level (HP:0003212)3.75193730
10Atrophic scars (HP:0001075)3.64939507
11Agitation (HP:0000713)3.62929419
12Severe Myopia (HP:0011003)3.61511348
13Epiphyseal dysplasia (HP:0002656)3.56955719
14Supranuclear gaze palsy (HP:0000605)3.55587479
15Premature rupture of membranes (HP:0001788)3.53269200
16Vitreoretinal degeneration (HP:0000655)3.53034054
17Midline defect of the nose (HP:0004122)3.32873321
18Severe visual impairment (HP:0001141)3.32352720
19Abnormal drinking behavior (HP:0030082)3.29404231
20Polydipsia (HP:0001959)3.29404231
21Aplasia/Hypoplasia of the pubic bone (HP:0009104)3.29289638
22Progressive cerebellar ataxia (HP:0002073)3.29032250
23Rib fusion (HP:0000902)3.27316757
24Down-sloping shoulders (HP:0200021)3.26729258
25Congenital stationary night blindness (HP:0007642)3.16519402
26Abnormal pancreas size (HP:0012094)3.07758671
27Shallow orbits (HP:0000586)3.05752824
28Hyperthyroidism (HP:0000836)3.05598518
29Focal seizures (HP:0007359)3.05109454
30Broad-based gait (HP:0002136)3.02683491
31Diastasis recti (HP:0001540)2.96840436
32Fragile skin (HP:0001030)2.96011180
33Absent eyelashes (HP:0000561)2.93502410
34Pachygyria (HP:0001302)2.90435921
35Abnormality of macular pigmentation (HP:0008002)2.85076233
36Aplasia involving bones of the extremities (HP:0009825)2.84909402
37Aplasia involving bones of the upper limbs (HP:0009823)2.84909402
38Aplasia of the phalanges of the hand (HP:0009802)2.84909402
39Optic nerve coloboma (HP:0000588)2.77813548
40Hypotrichosis (HP:0001006)2.76259510
41Tubular atrophy (HP:0000092)2.71166686
42Pancreatic fibrosis (HP:0100732)2.70857916
43Abnormality of the labia minora (HP:0012880)2.68909851
44Nephronophthisis (HP:0000090)2.65245607
45Arterial tortuosity (HP:0005116)2.64752746
46Anomalous pulmonary venous return (HP:0010772)2.58504096
47Neoplasm of the heart (HP:0100544)2.57534957
48Pancreatic cysts (HP:0001737)2.56838408
49Optic nerve hypoplasia (HP:0000609)2.56701851
50Abnormality of the corticospinal tract (HP:0002492)2.54764983
51Abnormality of the pubic bones (HP:0003172)2.54497872
52Fetal akinesia sequence (HP:0001989)2.52941622
53Protruding tongue (HP:0010808)2.51924764
54Decreased circulating renin level (HP:0003351)2.50680027
55Drooling (HP:0002307)2.47756851
56Abnormal hair laboratory examination (HP:0003328)2.46361851
57Abnormality of the renal cortex (HP:0011035)2.45558422
58Chin dimple (HP:0010751)2.42904312
59Abnormality of the renal medulla (HP:0100957)2.39243457
60Amblyopia (HP:0000646)2.39021817
61Radial bowing (HP:0002986)2.36606378
62Oligodactyly (hands) (HP:0001180)2.35823675
63Partial agenesis of the corpus callosum (HP:0001338)2.34569253
64Epileptiform EEG discharges (HP:0011182)2.33872892
65Aplasia/Hypoplasia of the sternum (HP:0006714)2.33769859
66Polyuria (HP:0000103)2.33404590
67Bicornuate uterus (HP:0000813)2.32963091
68Focal motor seizures (HP:0011153)2.31240546
69Ankyloglossia (HP:0010296)2.30660109
70Hyperacusis (HP:0010780)2.30429913
71Hepatoblastoma (HP:0002884)2.30282158
72EEG with generalized epileptiform discharges (HP:0011198)2.28860061
73Mixed hearing impairment (HP:0000410)2.28767662
74Hypsarrhythmia (HP:0002521)2.28319425
75Rectal prolapse (HP:0002035)2.27654229
76Excessive salivation (HP:0003781)2.27229182
77Alacrima (HP:0000522)2.26861093
78Skin pits (HP:0100276)2.26059749
79Eczematoid dermatitis (HP:0000976)2.25997252
80Vascular tortuosity (HP:0004948)2.25840095
81Pendular nystagmus (HP:0012043)2.25288939
82Hypoplastic ischia (HP:0003175)2.22117168
83Turricephaly (HP:0000262)2.21187497
84Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.20754748
85Short 4th metacarpal (HP:0010044)2.20754748
86Mild short stature (HP:0003502)2.16600561
87Cystic liver disease (HP:0006706)2.15405520
88Facial hemangioma (HP:0000329)2.14077200
89Abnormality of the lacrimal duct (HP:0011481)2.13512385
90Conjunctival hamartoma (HP:0100780)2.13498341
91Mitral valve prolapse (HP:0001634)2.12522959
92Enlarged kidneys (HP:0000105)2.11778870
93Abnormality of the pulmonary veins (HP:0011718)2.11313538
94Lissencephaly (HP:0001339)2.11239431
95Polyphagia (HP:0002591)2.10558190
96Bladder diverticulum (HP:0000015)2.09864006
97Abnormality of cells of the erythroid lineage (HP:0012130)2.09557665
98Molar tooth sign on MRI (HP:0002419)2.08289076
99Abnormality of midbrain morphology (HP:0002418)2.08289076
100Abnormality of the nasolacrimal system (HP:0000614)2.07752445
101Adrenal hypoplasia (HP:0000835)2.05995768
102Metaphyseal dysplasia (HP:0100255)2.02736666
103Abnormality of the labia majora (HP:0012881)2.02589866
104Aplasia/Hypoplasia of the brainstem (HP:0007362)2.02541342
105Hypoplasia of the brainstem (HP:0002365)2.02541342
106Abnormality of oral frenula (HP:0000190)2.02482991
107Hamartoma (HP:0010566)2.02390920
108Supernumerary ribs (HP:0005815)2.02020343
109Aortic dissection (HP:0002647)2.01730378
110Hyperphosphatemia (HP:0002905)2.01622524
111Abnormality of the ischium (HP:0003174)2.01548229
112Thick nail (HP:0001805)2.00991827
113Long toe (HP:0010511)2.00786324
114Oligodactyly (HP:0012165)2.00222393
115Abnormal auditory evoked potentials (HP:0006958)11.1050944
116Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.98979666
117Blepharitis (HP:0000498)1.98920132
118Epileptic encephalopathy (HP:0200134)1.98646754
119Ankle contracture (HP:0006466)1.98425524
120Plantar hyperkeratosis (HP:0007556)1.96491054
121Hamartoma of the eye (HP:0010568)1.96100491
122Polymicrogyria (HP:0002126)1.95899732
123Renovascular hypertension (HP:0100817)1.95674507
124Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)1.94895854
125Arnold-Chiari malformation (HP:0002308)1.94157963
126Type II lissencephaly (HP:0007260)1.93464327
127Abnormal urine output (HP:0012590)1.93199796
128Macroglossia (HP:0000158)1.91923255
129Parakeratosis (HP:0001036)1.91179095
130Abnormality of the 4th metacarpal (HP:0010012)1.90400187
131Anophthalmia (HP:0000528)1.90352927
132Broad ribs (HP:0000885)1.89976283
133Insomnia (HP:0100785)1.89466904
134Onycholysis (HP:0001806)1.89154400
135Hypoplastic labia majora (HP:0000059)1.88849203
136Palmoplantar hyperkeratosis (HP:0000972)1.88474396
137Choanal stenosis (HP:0000452)1.87086692
138Camptodactyly of toe (HP:0001836)1.86923898
139Overriding aorta (HP:0002623)1.85791008
140Elfin facies (HP:0004428)1.85300556
141Selective tooth agenesis (HP:0001592)1.84573305
142Bony spicule pigmentary retinopathy (HP:0007737)1.84046502
143Gait imbalance (HP:0002141)1.84000361
144True hermaphroditism (HP:0010459)1.83928568
145Congenital hepatic fibrosis (HP:0002612)1.83206637
146Abnormal number of incisors (HP:0011064)1.83191919
147Preauricular pit (HP:0004467)1.82088526
148Periauricular skin pits (HP:0100277)1.82088526
149Shawl scrotum (HP:0000049)1.81899443
150Pterygium (HP:0001059)1.81478430
151Neonatal hypoglycemia (HP:0001998)1.80919543
152Renal duplication (HP:0000075)1.80776731
153Elbow flexion contracture (HP:0002987)1.79687058
154Abnormal number of erythroid precursors (HP:0012131)1.79026450
155Restlessness (HP:0000711)1.78781485
156Hypoventilation (HP:0002791)1.78052299
157Vaginal atresia (HP:0000148)1.76399356
158Exotropia (HP:0000577)1.76275679
159Retinal detachment (HP:0000541)1.76098832
160Supernumerary bones of the axial skeleton (HP:0009144)1.75622359
161Scrotal hypoplasia (HP:0000046)1.75541950
162Chronic hepatic failure (HP:0100626)1.74836441
163Adactyly (HP:0009776)1.74370036
164Abolished electroretinogram (ERG) (HP:0000550)1.73634270
165Palmar hyperkeratosis (HP:0010765)1.73458576
166Medial flaring of the eyebrow (HP:0010747)1.72521203
167Stage 5 chronic kidney disease (HP:0003774)1.72514562
168Limb hypertonia (HP:0002509)1.72139664
169Decreased lacrimation (HP:0000633)1.71983774
170Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.71786490
171Anxiety (HP:0000739)1.70757633
172Genital tract atresia (HP:0001827)1.70313881
173Meningocele (HP:0002435)1.70264957
174Tubulointerstitial nephritis (HP:0001970)1.69809496
175Dilatation of the ascending aorta (HP:0005111)1.68654984
176Short phalanx of the thumb (HP:0009660)1.68569133
177Focal dystonia (HP:0004373)1.68566029
178Osteoarthritis (HP:0002758)1.68506914
179Renal dysplasia (HP:0000110)1.68226957
180Mildly elevated creatine phosphokinase (HP:0008180)1.67517566
181Labial hypoplasia (HP:0000066)1.67272324
182Humeroradial synostosis (HP:0003041)1.66709664
183Synostosis involving the elbow (HP:0003938)1.66709664
184Round ear (HP:0100830)1.63654886
185Hypoplastic nipples (HP:0002557)1.61858003
186Increased connective tissue (HP:0009025)1.61114700
187Facial shape deformation (HP:0011334)1.60729803
188Potter facies (HP:0002009)1.60729803
189Septo-optic dysplasia (HP:0100842)1.60473008

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA25.43044915
2EPHB14.57283179
3CASK4.30520397
4EPHA33.83017603
5MAPK153.59897581
6DDR23.36430882
7PINK13.26836446
8TXK2.90937217
9WNK42.89091921
10SIK22.80899870
11MUSK2.75833495
12MAP3K92.72288775
13FGFR42.69175437
14LATS12.58985808
15MAP4K22.55540363
16NTRK32.51791983
17CAMKK12.46758311
18DYRK22.39518799
19FER2.38370174
20NTRK12.31551281
21CAMK1D2.31353932
22CAMKK22.11517540
23EEF2K2.07459685
24MAP3K131.79441295
25TRPM71.70513497
26IRAK11.69460664
27PAK31.69134779
28LATS21.58043676
29MAP3K101.44956551
30MAPK131.44944959
31RIPK11.43549205
32TAOK11.37963357
33ERBB21.35905171
34KSR11.32635708
35MAP3K71.26185045
36MAP3K121.25736367
37ADRBK21.25511828
38EPHA41.24082334
39PRKD31.23293921
40ALK1.20705063
41PRKCE1.20077153
42CDK31.14315719
43PTK61.14105995
44DYRK1B1.10774375
45PNCK1.08442243
46MAP2K71.06966801
47MARK31.04496718
48TRIB31.03927458
49MAPKAPK31.02863232
50NTRK21.00931121
51BRSK11.00631909
52MINK10.99845771
53FGFR30.99321288
54STK38L0.96319582
55DMPK0.96304876
56RET0.95748872
57WNK30.95477333
58HIPK20.91608549
59BTK0.90540965
60WNK10.89906825
61SGK4940.87929346
62SGK2230.87929346
63MAP3K40.87912799
64MAP2K40.85921374
65MAPK110.85472160
66MST40.83088905
67DYRK30.82534819
68MAP3K110.82176767
69DAPK20.81713423
70MAP3K20.80990554
71SIK10.80011325
72MAP3K10.78633136
73CDK50.77716203
74CSNK1A1L0.76990672
75UHMK10.76877293
76PRKCG0.74253239
77FGFR10.73063972
78MAPK120.70924307
79TAOK30.69060196
80ROCK20.69044068
81BMX0.68816767
82INSRR0.67121397
83ZAK0.66888213
84PAK60.66456525
85MARK20.65591103
86LMTK20.65261032
87RPS6KB20.65010857
88RPS6KA60.63607105
89MAP2K20.62287461
90PRKACA0.60887284
91KSR20.60110245
92PAK40.59910209
93CDC42BPA0.59023721
94BCR0.58786334
95FYN0.57188653
96CAMK1G0.56686218
97TTN0.56484132
98RPS6KC10.55838530
99RPS6KL10.55838530
100PKN20.55616558
101CSNK1D0.53449291
102PRKCQ0.53157669
103RPS6KA10.52344478
104NME10.52062935
105CDK190.50915356
106DYRK1A0.50894720
107NLK0.50278885
108PKN10.49021252
109OXSR10.48360203
110RPS6KA20.48101096
111IRAK20.47866019
112PRKAA20.47806381
113TLK10.47723204
114CDK120.47216905
115AKT10.45913634
116MAPK40.44488672
117RIPK40.44246912
118EPHB20.43842127
119PRKAA10.43507010
120STK110.41073963
121GRK10.40675604
122PDK20.40609976
123CDK150.39051801
124TYRO30.38870908
125CSNK1E0.38745248
126PRKCH0.38215259
127CAMK2B0.38197648
128ERBB40.37889238
129CDK11A0.37590542
130CAMK10.37533990
131MTOR0.37076343
132MARK10.36775920
133LRRK20.36692228
134MAPK80.36303714
135CSNK1G20.36287374
136PHKG20.35597314
137PHKG10.35597314
138PRKCZ0.35540104
139MAPKAPK50.35430550
140MATK0.35312331
141MAPKAPK20.35167962
142CDK180.32921751
143LIMK10.32887069
144CDK140.32811953
145GSK3B0.32577854
146ITK0.31646040
147RPS6KA30.31426334
148PRKCI0.31293322
149CAMK40.30874260
150STK390.30694612
151MAPK90.29751731
152PRKD20.29117291
153CAMK2D0.28911754
154ICK0.28757354
155MAPK100.28659166
156PTK20.27763859
157EGFR0.27760123
158CAMK2G0.27713939
159CSNK1G30.27586430

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003603.09798214
2Sulfur relay system_Homo sapiens_hsa041222.84116054
3Cardiac muscle contraction_Homo sapiens_hsa042602.80737663
4Phototransduction_Homo sapiens_hsa047442.63544329
5Cell adhesion molecules (CAMs)_Homo sapiens_hsa045142.42543252
6Morphine addiction_Homo sapiens_hsa050322.38392381
7Oxidative phosphorylation_Homo sapiens_hsa001902.36959532
8Parkinsons disease_Homo sapiens_hsa050122.35871036
9Histidine metabolism_Homo sapiens_hsa003402.06193468
10Basal cell carcinoma_Homo sapiens_hsa052172.02675937
11Graft-versus-host disease_Homo sapiens_hsa053321.97767750
12Ribosome_Homo sapiens_hsa030101.85882125
13Regulation of autophagy_Homo sapiens_hsa041401.85178783
14Leukocyte transendothelial migration_Homo sapiens_hsa046701.79664870
15Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.76271018
16Tight junction_Homo sapiens_hsa045301.69047832
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.67164896
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.63398933
19Protein digestion and absorption_Homo sapiens_hsa049741.60077046
20ECM-receptor interaction_Homo sapiens_hsa045121.58832937
21Alzheimers disease_Homo sapiens_hsa050101.58401182
22Huntingtons disease_Homo sapiens_hsa050161.56210876
23Basal transcription factors_Homo sapiens_hsa030221.55876455
24Hedgehog signaling pathway_Homo sapiens_hsa043401.55021016
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.48012625
26Axon guidance_Homo sapiens_hsa043601.43468482
27Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.42135274
28Hippo signaling pathway_Homo sapiens_hsa043901.41335696
29Olfactory transduction_Homo sapiens_hsa047401.41210964
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40515055
31Melanogenesis_Homo sapiens_hsa049161.39406366
32ErbB signaling pathway_Homo sapiens_hsa040121.38806715
33Amphetamine addiction_Homo sapiens_hsa050311.36673618
34Fatty acid biosynthesis_Homo sapiens_hsa000611.35684729
35Estrogen signaling pathway_Homo sapiens_hsa049151.30630459
36Steroid biosynthesis_Homo sapiens_hsa001001.29253732
37Synaptic vesicle cycle_Homo sapiens_hsa047211.28242371
38Cocaine addiction_Homo sapiens_hsa050301.25849114
39Tyrosine metabolism_Homo sapiens_hsa003501.23771084
40Gastric acid secretion_Homo sapiens_hsa049711.22779334
41Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.22208179
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.22191730
43Wnt signaling pathway_Homo sapiens_hsa043101.21548063
44Hepatitis C_Homo sapiens_hsa051601.19957322
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.19692071
46Dorso-ventral axis formation_Homo sapiens_hsa043201.18711405
47Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.17385609
48Adherens junction_Homo sapiens_hsa045201.16455956
49Nicotine addiction_Homo sapiens_hsa050331.15788420
50beta-Alanine metabolism_Homo sapiens_hsa004101.15480548
51Circadian entrainment_Homo sapiens_hsa047131.14309489
52Long-term potentiation_Homo sapiens_hsa047201.13368551
53Salivary secretion_Homo sapiens_hsa049701.12013180
54Type II diabetes mellitus_Homo sapiens_hsa049301.11085324
55Focal adhesion_Homo sapiens_hsa045101.09701314
56Glioma_Homo sapiens_hsa052141.09118681
57Dopaminergic synapse_Homo sapiens_hsa047281.07629176
58Glutamatergic synapse_Homo sapiens_hsa047241.05262084
59Proteoglycans in cancer_Homo sapiens_hsa052051.03746594
60Aldosterone synthesis and secretion_Homo sapiens_hsa049251.03461239
61Amoebiasis_Homo sapiens_hsa051461.02526877
62Dilated cardiomyopathy_Homo sapiens_hsa054141.02335355
63GABAergic synapse_Homo sapiens_hsa047270.98420025
64Oxytocin signaling pathway_Homo sapiens_hsa049210.98252811
65Serotonergic synapse_Homo sapiens_hsa047260.98057479
66Insulin secretion_Homo sapiens_hsa049110.97743014
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.97316911
68Taste transduction_Homo sapiens_hsa047420.97261701
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.95951714
70Chronic myeloid leukemia_Homo sapiens_hsa052200.95303736
71AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.95128300
72GnRH signaling pathway_Homo sapiens_hsa049120.93182714
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.92056865
74Notch signaling pathway_Homo sapiens_hsa043300.90975612
75Renal cell carcinoma_Homo sapiens_hsa052110.90762203
76Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89633045
77Cholinergic synapse_Homo sapiens_hsa047250.88710956
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.87826558
79Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.87499270
80Antigen processing and presentation_Homo sapiens_hsa046120.87316374
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.86020444
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.85484182
83Linoleic acid metabolism_Homo sapiens_hsa005910.84439426
84Rap1 signaling pathway_Homo sapiens_hsa040150.83725049
85Renin secretion_Homo sapiens_hsa049240.82728554
86cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80601120
87Thyroid hormone synthesis_Homo sapiens_hsa049180.80535975
88Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.80201969
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78895851
90Endometrial cancer_Homo sapiens_hsa052130.77357215
91Colorectal cancer_Homo sapiens_hsa052100.77129379
92MAPK signaling pathway_Homo sapiens_hsa040100.75713915
93Lysine degradation_Homo sapiens_hsa003100.75423906
94Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74561233
95Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74410903
96Pancreatic cancer_Homo sapiens_hsa052120.73598983
97FoxO signaling pathway_Homo sapiens_hsa040680.72853804
98Insulin resistance_Homo sapiens_hsa049310.72016317
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.71948769
100Ovarian steroidogenesis_Homo sapiens_hsa049130.71587511
101Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70522378
102cAMP signaling pathway_Homo sapiens_hsa040240.70162241
103Gap junction_Homo sapiens_hsa045400.70039289
104Prion diseases_Homo sapiens_hsa050200.69406612
105Ras signaling pathway_Homo sapiens_hsa040140.69056789
106Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.69037450
107MicroRNAs in cancer_Homo sapiens_hsa052060.68926022
108Prolactin signaling pathway_Homo sapiens_hsa049170.68156963
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67277785
110Calcium signaling pathway_Homo sapiens_hsa040200.67009566
111Acute myeloid leukemia_Homo sapiens_hsa052210.66460291
112Glycerophospholipid metabolism_Homo sapiens_hsa005640.66427798
113Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.66213081
114VEGF signaling pathway_Homo sapiens_hsa043700.65720192
115Ether lipid metabolism_Homo sapiens_hsa005650.65567080
116Maturity onset diabetes of the young_Homo sapiens_hsa049500.65306369
117Nitrogen metabolism_Homo sapiens_hsa009100.65056441
118Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64074174
119Glycerolipid metabolism_Homo sapiens_hsa005610.64033523
120Insulin signaling pathway_Homo sapiens_hsa049100.63466934
121Melanoma_Homo sapiens_hsa052180.61914864
122Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.61353724
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59947731
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.59690429
125Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58343149
126Long-term depression_Homo sapiens_hsa047300.57629303
127Butanoate metabolism_Homo sapiens_hsa006500.56586838
128Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56059482
129Phospholipase D signaling pathway_Homo sapiens_hsa040720.55689504
130Adipocytokine signaling pathway_Homo sapiens_hsa049200.55372167
131Vibrio cholerae infection_Homo sapiens_hsa051100.55137699
132Pathways in cancer_Homo sapiens_hsa052000.53928473
133Prostate cancer_Homo sapiens_hsa052150.53288857
134Non-small cell lung cancer_Homo sapiens_hsa052230.53277375
135T cell receptor signaling pathway_Homo sapiens_hsa046600.49554689
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48902397
137Alcoholism_Homo sapiens_hsa050340.47567938
138Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.46174393
139Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39701972
140Endocytosis_Homo sapiens_hsa041440.35332955
141Steroid hormone biosynthesis_Homo sapiens_hsa001400.33744953
142Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33447251
143Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.32453020
144Glucagon signaling pathway_Homo sapiens_hsa049220.26944000
145ABC transporters_Homo sapiens_hsa020100.26725459
146Sulfur metabolism_Homo sapiens_hsa009200.25830150
147Bile secretion_Homo sapiens_hsa049760.25362512

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