CCL24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* eosinophil chemotaxis (GO:0048245)7.69171877
2fat-soluble vitamin biosynthetic process (GO:0042362)7.45938899
3* eosinophil migration (GO:0072677)6.68483132
4glycosphingolipid catabolic process (GO:0046479)6.54552472
5monocyte chemotaxis (GO:0002548)6.30046254
6positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)6.27148580
7neutrophil activation involved in immune response (GO:0002283)6.16796701
8glycolipid catabolic process (GO:0019377)5.95338721
9positive regulation of bone resorption (GO:0045780)5.86705419
10positive regulation of bone remodeling (GO:0046852)5.86705419
11oligosaccharide catabolic process (GO:0009313)5.82774857
12cellular response to ethanol (GO:0071361)5.81353583
13phagocytosis, engulfment (GO:0006911)5.49898239
14regulation of lymphocyte chemotaxis (GO:1901623)5.46514072
15ceramide catabolic process (GO:0046514)5.28573142
16lipoxygenase pathway (GO:0019372)5.20447217
17cellular response to thyroid hormone stimulus (GO:0097067)5.08009957
18pinocytosis (GO:0006907)5.01147480
19amino sugar catabolic process (GO:0046348)4.90964006
20positive regulation of lymphocyte migration (GO:2000403)4.84392200
21cellular extravasation (GO:0045123)4.76874336
22production of molecular mediator involved in inflammatory response (GO:0002532)4.76547484
23positive regulation of monocyte chemotaxis (GO:0090026)4.72024323
24regulation of MHC class II biosynthetic process (GO:0045346)4.54333790
25membrane lipid catabolic process (GO:0046466)4.52700475
26vitamin D metabolic process (GO:0042359)4.51248642
27regulation of syncytium formation by plasma membrane fusion (GO:0060142)4.46982553
28osteoclast differentiation (GO:0030316)4.45362668
29peptide catabolic process (GO:0043171)4.45347267
30microglial cell activation (GO:0001774)4.38929475
31regulation of apoptotic cell clearance (GO:2000425)4.35337235
32regulation of lymphocyte migration (GO:2000401)4.24082222
33macrophage activation involved in immune response (GO:0002281)4.22805764
34response to peptidoglycan (GO:0032494)4.19553212
35positive regulation of macrophage differentiation (GO:0045651)4.13348846
36barbed-end actin filament capping (GO:0051016)4.10919462
37macrophage activation (GO:0042116)4.07587815
38glucosamine-containing compound catabolic process (GO:1901072)4.04522159
39positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.02788749
40positive regulation of cellular amide metabolic process (GO:0034250)3.97571476
41phagosome maturation (GO:0090382)3.95830327
42response to thyroid hormone (GO:0097066)3.95758981
43sexual reproduction (GO:0019953)3.95237727
44phospholipid efflux (GO:0033700)3.92418455
45positive regulation of leukocyte degranulation (GO:0043302)3.92129097
46superoxide anion generation (GO:0042554)3.87967673
47modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.87527977
48positive regulation by organism of defense response of other organism involved in symbiotic interact3.87527977
49modulation by symbiont of host immune response (GO:0052553)3.87527977
50positive regulation by symbiont of host defense response (GO:0052509)3.87527977
51modulation by symbiont of host defense response (GO:0052031)3.87527977
52modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.87527977
53positive regulation of tissue remodeling (GO:0034105)3.86634967
54antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.85479646
55membrane invagination (GO:0010324)3.81351547
56positive regulation of cholesterol efflux (GO:0010875)3.81011967
57regulation of macrophage chemotaxis (GO:0010758)3.79702423
58hydrogen peroxide biosynthetic process (GO:0050665)3.79433463
59positive regulation of interferon-alpha production (GO:0032727)3.78926103
60negative regulation of granulocyte differentiation (GO:0030853)3.77587082
61sphingolipid catabolic process (GO:0030149)3.76315547
62regulation of interferon-alpha production (GO:0032647)3.72417071
63granulocyte activation (GO:0036230)3.71796473
64regulation of mononuclear cell migration (GO:0071675)3.70710317
65bile acid biosynthetic process (GO:0006699)3.69459307
66regulation of monocyte differentiation (GO:0045655)3.65563566
67positive regulation of extracellular matrix organization (GO:1903055)3.64084721
68lens fiber cell differentiation (GO:0070306)3.63158164
69myeloid cell activation involved in immune response (GO:0002275)3.62761062
70positive regulation of gamma-delta T cell activation (GO:0046645)3.62151525
71negative regulation of interleukin-17 production (GO:0032700)3.61550555
72neutrophil chemotaxis (GO:0030593)3.59901589
73positive regulation of macrophage derived foam cell differentiation (GO:0010744)3.56394991
74positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.56033843
75vitamin biosynthetic process (GO:0009110)3.54970464
76lymphocyte chemotaxis (GO:0048247)3.53415900
77negative regulation of interleukin-12 production (GO:0032695)3.51454007
78neutrophil migration (GO:1990266)3.50724927
79positive regulation of interleukin-1 beta secretion (GO:0050718)3.49133595
80regulation of monocyte chemotaxis (GO:0090025)3.48249082
81neutrophil activation (GO:0042119)3.47739877
82response to muramyl dipeptide (GO:0032495)3.46185556
83positive regulation of sterol transport (GO:0032373)3.46014749
84positive regulation of cholesterol transport (GO:0032376)3.46014749
85regulation of interferon-beta biosynthetic process (GO:0045357)3.45308085
86lipopolysaccharide-mediated signaling pathway (GO:0031663)3.44400971
87regulation of macrophage derived foam cell differentiation (GO:0010743)3.39494798
88regulation of B cell receptor signaling pathway (GO:0050855)3.39239379
89reactive oxygen species biosynthetic process (GO:1903409)3.34302463
90glucose 6-phosphate metabolic process (GO:0051156)3.32854629
91plasma lipoprotein particle assembly (GO:0034377)3.31484141
92positive regulation of mast cell activation (GO:0033005)3.31095139
93positive regulation of B cell differentiation (GO:0045579)3.30837334
94decidualization (GO:0046697)3.25089179
95positive regulation of interleukin-1 secretion (GO:0050716)3.23989948
96negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.21186255
97positive regulation of mast cell degranulation (GO:0043306)3.19802270
98positive regulation of mast cell activation involved in immune response (GO:0033008)3.19802270
99cellular response to zinc ion (GO:0071294)3.17399725
100regulation of interleukin-1 beta secretion (GO:0050706)3.17182191
101myeloid dendritic cell differentiation (GO:0043011)3.16935106
102leukotriene biosynthetic process (GO:0019370)3.15919006
103complement activation, alternative pathway (GO:0006957)3.15896342
104macrophage differentiation (GO:0030225)3.14025806
105negative regulation of nitric oxide biosynthetic process (GO:0045019)3.13550804
106detection of molecule of bacterial origin (GO:0032490)3.12722349
107negative regulation of leukocyte chemotaxis (GO:0002689)3.12349553
108macrophage chemotaxis (GO:0048246)3.11768838
109positive regulation of antigen processing and presentation (GO:0002579)3.11226592
110cellular response to cadmium ion (GO:0071276)3.10872212
111T cell migration (GO:0072678)3.10695638
112* granulocyte chemotaxis (GO:0071621)3.09801633
113respiratory burst (GO:0045730)3.09502425
114transferrin transport (GO:0033572)3.09265627
115positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)3.09261255
116reverse cholesterol transport (GO:0043691)3.06305446
117positive regulation of leukocyte chemotaxis (GO:0002690)3.05704052
118regulation of bone resorption (GO:0045124)3.05228560
119low-density lipoprotein particle remodeling (GO:0034374)3.04300791
120apoptotic cell clearance (GO:0043277)3.03406415
121positive regulation of calcium ion import (GO:0090280)3.03364236
122L-glutamate transport (GO:0015813)3.03301985
123detection of other organism (GO:0098543)3.01383252
124positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.00596244
125cyclooxygenase pathway (GO:0019371)2.98567577
126myeloid dendritic cell activation (GO:0001773)2.97451257
127positive regulation of T cell migration (GO:2000406)2.97021731
128regulation of interleukin-1 secretion (GO:0050704)2.96889460
129regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.96528452
130leukotriene metabolic process (GO:0006691)2.96042526
131positive regulation of tumor necrosis factor production (GO:0032760)2.95773759
132negative regulation of bone resorption (GO:0045779)2.95257240
133* granulocyte migration (GO:0097530)2.95074723
134response to lipoprotein particle (GO:0055094)2.92499094
135regulation of cholesterol storage (GO:0010885)2.92090154
136positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.91445213
137protein-lipid complex assembly (GO:0065005)2.90326684
138regulation of vitamin D biosynthetic process (GO:0060556)2.90296279
139regulation of mast cell activation (GO:0033003)2.88448131
140mannose metabolic process (GO:0006013)2.88306285
141positive regulation of smooth muscle cell migration (GO:0014911)2.87370311
142protein localization to endosome (GO:0036010)2.87121628
143positive regulation of phagocytosis (GO:0050766)2.86786740
144regulation of integrin activation (GO:0033623)2.86364812
145regulation of leukocyte chemotaxis (GO:0002688)2.85120849
146immunoglobulin mediated immune response (GO:0016064)2.85029328
147negative regulation of lipid storage (GO:0010888)2.83799293
148regulation of T cell migration (GO:2000404)2.83742211
149positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.83697220
150regulation of leukocyte degranulation (GO:0043300)2.83440766
151pyrimidine-containing compound transmembrane transport (GO:0072531)2.83351332
152* leukocyte chemotaxis (GO:0030595)2.83243631
153trivalent inorganic cation transport (GO:0072512)2.83059392
154ferric iron transport (GO:0015682)2.83059392
155regulation of macrophage differentiation (GO:0045649)2.82195752
156regulation of antigen processing and presentation (GO:0002577)2.81819271
157regulation of platelet activation (GO:0010543)2.81715436
158regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.81518488
159polyol biosynthetic process (GO:0046173)2.81470322
160angiotensin maturation (GO:0002003)2.81264834
161acidic amino acid transport (GO:0015800)2.80759506
162positive regulation of osteoclast differentiation (GO:0045672)2.79697890
163regulation of cholesterol esterification (GO:0010872)2.78279474
164phospholipid homeostasis (GO:0055091)2.77876373
165glial cell migration (GO:0008347)2.77043625
166* myeloid leukocyte migration (GO:0097529)2.76496392
167iron ion import (GO:0097286)2.75519789
168myeloid leukocyte activation (GO:0002274)2.75125374
169lipopolysaccharide metabolic process (GO:0008653)2.75108698
170intracellular pH reduction (GO:0051452)2.75022212
171regulation of vitamin metabolic process (GO:0030656)2.74865539
172ganglioside metabolic process (GO:0001573)2.73739972
173complement activation (GO:0006956)2.72061433
174regulation of dendritic cell antigen processing and presentation (GO:0002604)2.71312714
175response to cholesterol (GO:0070723)2.69768294

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.77959077
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.50758836
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.70162379
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.69224741
5SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.58813600
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.61979873
7NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.49075304
8* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.48134013
9NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.99032461
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.69627296
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.53492533
12STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.50796966
13PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse2.45705430
14RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.45062036
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.40900345
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.34711009
17SCL_19346495_ChIP-Seq_HPC-7_Human2.23779360
18VDR_24787735_ChIP-Seq_THP-1_Human2.23659748
19EGR1_19032775_ChIP-ChIP_M12_Human2.13020593
20STAT4_19710469_ChIP-ChIP_TH1__Mouse2.00181067
21SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.94180729
22LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.93634869
23RUNX_20019798_ChIP-Seq_JUKART_Human1.89923768
24IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84442115
25GATA2_21666600_ChIP-Seq_HMVEC_Human1.81981291
26PU_27001747_Chip-Seq_BMDM_Mouse1.73579760
27NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.72030947
28BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69516430
29VDR_24763502_ChIP-Seq_THP-1_Human1.69203173
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.67292450
31PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.66338696
32RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.62449712
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57794824
34WT1_19549856_ChIP-ChIP_CCG9911_Human1.51378139
35THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.49267887
36CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.49215915
37* SPI1_23547873_ChIP-Seq_NB4_Human1.48817485
38ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.48257576
39LXR_22158963_ChIP-Seq_LIVER_Mouse1.48128780
40SPI1_23127762_ChIP-Seq_K562_Human1.47537241
41NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.46715102
42CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.45710884
43RXR_22158963_ChIP-Seq_LIVER_Mouse1.43054238
44LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.41872552
45CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.40966278
46TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.39421474
47CDX2_19796622_ChIP-Seq_MESCs_Mouse1.39343134
48CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.35945338
49EGR1_23403033_ChIP-Seq_LIVER_Mouse1.35458074
50FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.34048187
51RUNX1_22412390_ChIP-Seq_EML_Mouse1.32741567
52E2F7_22180533_ChIP-Seq_HELA_Human1.32292294
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.31628575
54TFEB_21752829_ChIP-Seq_HELA_Human1.31054650
55FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.27856484
56PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27330609
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.21817647
58CDX2_20551321_ChIP-Seq_CACO-2_Human1.21667377
59FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.20997352
60CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.20897419
61PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.20122902
62GATA1_19941826_ChIP-Seq_K562_Human1.19695787
63TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.19654176
64* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.17666226
65PPARA_22158963_ChIP-Seq_LIVER_Mouse1.16166053
66KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.15760948
67KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.15760948
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.15760948
69MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15726736
70VDR_21846776_ChIP-Seq_THP-1_Human1.14984084
71STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13533088
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.13130289
73PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.11778144
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11689461
75BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.10553876
76SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.10390367
77TP53_16413492_ChIP-PET_HCT116_Human1.08553580
78LXR_22292898_ChIP-Seq_THP-1_Human1.06476046
79TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.05704487
80CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05296610
81SOX2_27498859_Chip-Seq_STOMACH_Mouse1.02595233
82MAF_26560356_Chip-Seq_TH1_Human1.02249309
83GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.01992219
84RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01894778
85CJUN_26792858_Chip-Seq_BT549_Human1.01257224
86NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.01072794
87SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98614494
88SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98143057
89GATA2_19941826_ChIP-Seq_K562_Human0.98115851
90CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.97912642
91CLOCK_20551151_ChIP-Seq_293T_Human0.96888148
92PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95771617
93GATA2_22383799_ChIP-Seq_G1ME_Mouse0.94273665
94ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.93973900
95SPI1_20517297_ChIP-Seq_HL60_Human0.93006653
96GATA3_26560356_Chip-Seq_TH2_Human0.91815109
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91644875
98* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90909110
99GATA1_22025678_ChIP-Seq_K562_Human0.90658053
100SALL4_18804426_ChIP-ChIP_XEN_Mouse0.90007214
101STAT6_21828071_ChIP-Seq_BEAS2B_Human0.88915324
102RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88235619
103SOX2_20726797_ChIP-Seq_SW620_Human0.87798581
104ESR1_20079471_ChIP-ChIP_T-47D_Human0.87676718
105NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87074550
106NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87074550
107MYB_26560356_Chip-Seq_TH2_Human0.86995560
108CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.86411348
109* GATA3_27048872_Chip-Seq_THYMUS_Human0.85375981
110BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.84586927
111ESR1_21235772_ChIP-Seq_MCF-7_Human0.82688208
112FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.81199633
113BCL6_27268052_Chip-Seq_Bcells_Human0.80339624
114GATA1_19941827_ChIP-Seq_MEL_Mouse0.80238546
115CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.79770155
116MYB_26560356_Chip-Seq_TH1_Human0.78982072
117JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78919110
118ESR2_21235772_ChIP-Seq_MCF-7_Human0.78437705
119EGR1_19374776_ChIP-ChIP_THP-1_Human0.78424253
120E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.77526172
121CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.77348079
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.77043297
123TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77043297
124KDM2B_26808549_Chip-Seq_SUP-B15_Human0.75233332
125PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.73560207
126CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.73083821
127PPAR_26484153_Chip-Seq_NCI-H1993_Human0.72523254

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell4.92957553
2MP0002254_reproductive_system_inflammat4.25718106
3MP0002148_abnormal_hypersensitivity_rea4.05713706
4MP0003436_decreased_susceptibility_to4.03273780
5MP0005058_abnormal_lysosome_morphology4.01467894
6MP0001835_abnormal_antigen_presentation3.83415690
7MP0002419_abnormal_innate_immunity3.15981440
8MP0003195_calcinosis3.09267096
9MP0005451_abnormal_body_composition3.04671804
10MP0003191_abnormal_cellular_cholesterol2.98455132
11MP0005000_abnormal_immune_tolerance2.75610808
12MP0003690_abnormal_glial_cell2.67808105
13MP0002877_abnormal_melanocyte_morpholog2.58460067
14MP0000343_altered_response_to2.56799802
15MP0003724_increased_susceptibility_to2.56491405
16MP0009278_abnormal_bone_marrow2.49682757
17MP0005025_abnormal_response_to2.48323451
18MP0002452_abnormal_antigen_presenting2.38436276
19MP0001800_abnormal_humoral_immune2.37640711
20MP0005671_abnormal_response_to2.30021685
21MP0003303_peritoneal_inflammation2.29058840
22MP0001533_abnormal_skeleton_physiology2.27639131
23MP0005464_abnormal_platelet_physiology2.25306928
24MP0006082_CNS_inflammation2.25028424
25MP0009785_altered_susceptibility_to2.21766178
26MP0002139_abnormal_hepatobiliary_system2.20157215
27MP0003806_abnormal_nucleotide_metabolis2.19293370
28MP0002723_abnormal_immune_serum2.15176312
29MP0002405_respiratory_system_inflammati2.02922523
30* MP0005387_immune_system_phenotype2.01029155
31* MP0001790_abnormal_immune_system2.01029155
32MP0003075_altered_response_to2.00302555
33MP0000604_amyloidosis1.98185102
34MP0002420_abnormal_adaptive_immunity1.94161094
35MP0005365_abnormal_bile_salt1.93753063
36MP0003329_amyloid_beta_deposits1.91986410
37MP0000685_abnormal_immune_system1.91086299
38MP0001819_abnormal_immune_cell1.90861109
39MP0001853_heart_inflammation1.84684934
40MP0005397_hematopoietic_system_phenotyp1.81867295
41MP0001545_abnormal_hematopoietic_system1.81867295
42MP0003279_aneurysm1.80712756
43MP0001845_abnormal_inflammatory_respons1.69315267
44MP0004233_abnormal_muscle_weight1.66281080
45MP0002138_abnormal_hepatobiliary_system1.62799228
46MP0005085_abnormal_gallbladder_physiolo1.62754361
47MP0008469_abnormal_protein_level1.55922144
48MP0004510_myositis1.46607929
49MP0009764_decreased_sensitivity_to1.45579850
50MP0003656_abnormal_erythrocyte_physiolo1.44760624
51MP0010368_abnormal_lymphatic_system1.43674869
52MP0005164_abnormal_response_to1.42919658
53MP0003828_pulmonary_edema1.40999300
54MP0002277_abnormal_respiratory_mucosa1.38820849
55MP0010234_abnormal_vibrissa_follicle1.38685766
56MP0005310_abnormal_salivary_gland1.35364167
57MP0004883_abnormal_blood_vessel1.33543905
58MP0004019_abnormal_vitamin_homeostasis1.33212314
59MP0001727_abnormal_embryo_implantation1.30990767
60MP0002998_abnormal_bone_remodeling1.30459286
61MP0002638_abnormal_pupillary_reflex1.28621012
62MP0009333_abnormal_splenocyte_physiolog1.27038232
63MP0000716_abnormal_immune_system1.20877386
64MP0000689_abnormal_spleen_morphology1.17397803
65MP0005390_skeleton_phenotype1.15055197
66MP0008260_abnormal_autophagy1.14674049
67MP0005167_abnormal_blood-brain_barrier1.12601293
68MP0005166_decreased_susceptibility_to1.11534892
69MP0003453_abnormal_keratinocyte_physiol1.10504318
70MP0002132_abnormal_respiratory_system1.08909336
71MP0010155_abnormal_intestine_physiology1.08513649
72MP0003091_abnormal_cell_migration1.07993195
73MP0001851_eye_inflammation1.07701348
74MP0000015_abnormal_ear_pigmentation1.06315185
75MP0009763_increased_sensitivity_to1.05993398
76MP0000249_abnormal_blood_vessel1.01698594
77MP0002398_abnormal_bone_marrow1.00304506
78MP0002295_abnormal_pulmonary_circulatio0.99741479
79MP0002429_abnormal_blood_cell0.99551870
80MP0004947_skin_inflammation0.97955172
81MP0003183_abnormal_peptide_metabolism0.95322888
82MP0000767_abnormal_smooth_muscle0.93921288
83MP0003448_altered_tumor_morphology0.93737686
84MP0002896_abnormal_bone_mineralization0.92935243
85MP0000920_abnormal_myelination0.92805501
86MP0004782_abnormal_surfactant_physiolog0.91435738
87MP0005174_abnormal_tail_pigmentation0.89223093
88MP0002722_abnormal_immune_system0.89192774
89MP0003172_abnormal_lysosome_physiology0.88578093
90MP0004147_increased_porphyrin_level0.88439459
91MP0008875_abnormal_xenobiotic_pharmacok0.88351858
92MP0010329_abnormal_lipoprotein_level0.87869257
93MP0000609_abnormal_liver_physiology0.86554491
94MP0001186_pigmentation_phenotype0.85963022
95MP0005023_abnormal_wound_healing0.85284304
96MP0008438_abnormal_cutaneous_collagen0.84043122
97MP0000569_abnormal_digit_pigmentation0.83733805
98MP0002075_abnormal_coat/hair_pigmentati0.83607832
99MP0008874_decreased_physiological_sensi0.83544329
100MP0001666_abnormal_nutrient_absorption0.83500709
101MP0003186_abnormal_redox_activity0.80606214
102MP0009115_abnormal_fat_cell0.80007594
103MP0002136_abnormal_kidney_physiology0.77838031
104MP0003300_gastrointestinal_ulcer0.76449655
105MP0005647_abnormal_sex_gland0.73781481
106MP0005076_abnormal_cell_differentiation0.73570988
107MP0001915_intracranial_hemorrhage0.73194045
108MP0005165_increased_susceptibility_to0.72139943
109MP0002166_altered_tumor_susceptibility0.72133490
110MP0002837_dystrophic_cardiac_calcinosis0.71469580
111MP0005584_abnormal_enzyme/coenzyme_acti0.70374709
112MP0003795_abnormal_bone_structure0.70260802
113MP0003632_abnormal_nervous_system0.70056754
114MP0000465_gastrointestinal_hemorrhage0.69058779
115MP0004808_abnormal_hematopoietic_stem0.68965563
116MP0002090_abnormal_vision0.68707850
117MP0009765_abnormal_xenobiotic_induced0.66639602
118MP0005646_abnormal_pituitary_gland0.66580820
119MP0000858_altered_metastatic_potential0.66086031
120MP0003763_abnormal_thymus_physiology0.63056503
121MP0005360_urolithiasis0.62840600
122MP0005171_absent_coat_pigmentation0.62107470
123MP0003633_abnormal_nervous_system0.57895989
124MP0002396_abnormal_hematopoietic_system0.56419525
125MP0001873_stomach_inflammation0.55524772
126MP0000371_diluted_coat_color0.55072925
127MP0005197_abnormal_uvea_morphology0.53627880
128MP0005248_abnormal_Harderian_gland0.52968575
129MP0002118_abnormal_lipid_homeostasis0.51809634
130MP0005332_abnormal_amino_acid0.50954248
131MP0005319_abnormal_enzyme/_coenzyme0.50914282

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)9.59231757
2Abnormality of liposaccharide metabolism (HP:0010968)7.12337287
3Abnormality of glycosphingolipid metabolism (HP:0004343)7.12337287
4Abnormality of glycolipid metabolism (HP:0010969)7.12337287
5Glomerulonephritis (HP:0000099)6.54141666
6Recurrent abscess formation (HP:0002722)6.20700436
7Complement deficiency (HP:0004431)5.75972513
8Recurrent bacterial skin infections (HP:0005406)5.67215623
9Abnormality of complement system (HP:0005339)5.34660571
10Eczematoid dermatitis (HP:0000976)5.25221930
11Epidermoid cyst (HP:0200040)5.23845955
12Disinhibition (HP:0000734)5.16762865
13Vacuolated lymphocytes (HP:0001922)4.98101166
14Axonal loss (HP:0003447)4.58885305
15Spontaneous hematomas (HP:0007420)4.58475819
16Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)4.51781440
17Recurrent gram-negative bacterial infections (HP:0005420)4.43763277
18Abnormality of the periventricular white matter (HP:0002518)4.16348048
19Joint hemorrhage (HP:0005261)4.02519607
20Skin nodule (HP:0200036)4.02184347
21Prostate neoplasm (HP:0100787)3.97218735
22Agnosia (HP:0010524)3.84870650
23Abnormality of macrophages (HP:0004311)3.77816775
24Dysostosis multiplex (HP:0000943)3.74047836
25Nephritis (HP:0000123)3.70190715
26Neurofibrillary tangles (HP:0002185)3.67125180
27Loss of speech (HP:0002371)3.52505061
28Upper motor neuron abnormality (HP:0002127)3.51027330
29Metaphyseal irregularity (HP:0003025)3.49105826
30Mediastinal lymphadenopathy (HP:0100721)3.40262965
31Increased neuronal autofluorescent lipopigment (HP:0002074)3.33130881
32Increased cerebral lipofuscin (HP:0011813)3.28905391
33Progressive visual loss (HP:0000529)3.24083743
34Myocardial infarction (HP:0001658)3.18629603
35Inappropriate behavior (HP:0000719)3.00753879
36Abnormality of the common coagulation pathway (HP:0010990)3.00613238
37Multiple lipomas (HP:0001012)2.99589275
38Orchitis (HP:0100796)2.97016743
39Retinal atrophy (HP:0001105)2.96877312
40Recurrent skin infections (HP:0001581)2.96677178
41Peripheral demyelination (HP:0011096)2.96630710
42Pustule (HP:0200039)2.92625203
43Myositis (HP:0100614)2.86601840
44Nausea (HP:0002018)2.85463901
45Basal ganglia calcification (HP:0002135)2.80577182
46Osteolytic defects of the hand bones (HP:0009699)2.66776926
47Osteolytic defects of the phalanges of the hand (HP:0009771)2.66776926
48Gingivitis (HP:0000230)2.65698889
49Mucopolysacchariduria (HP:0008155)2.65008696
50Urinary glycosaminoglycan excretion (HP:0003541)2.65008696
51Pseudobulbar signs (HP:0002200)2.61199189
52Retrobulbar optic neuritis (HP:0100654)2.58396538
53Optic neuritis (HP:0100653)2.58396538
54Cerebral inclusion bodies (HP:0100314)2.57966135
55Malnutrition (HP:0004395)2.55890600
56Segmental peripheral demyelination/remyelination (HP:0003481)2.54009243
57Protuberant abdomen (HP:0001538)2.46342101
58Hepatosplenomegaly (HP:0001433)2.44980093
59Hypoalphalipoproteinemia (HP:0003233)2.42959831
60Dysphonia (HP:0001618)2.40823013
61Abnormality of the prostate (HP:0008775)2.36684420
62Obstructive lung disease (HP:0006536)2.36666154
63Chronic obstructive pulmonary disease (HP:0006510)2.36666154
64Thin bony cortex (HP:0002753)2.34656358
65Panhypogammaglobulinemia (HP:0003139)2.31400777
66Diminished motivation (HP:0000745)2.31322428
67Abnormality of the phalanges of the 2nd finger (HP:0009541)2.31266150
68Abnormality of glycosaminoglycan metabolism (HP:0004371)2.29457375
69Abnormality of mucopolysaccharide metabolism (HP:0011020)2.29457375
70Abnormality of polysaccharide metabolism (HP:0011012)2.29457375
71Recurrent fungal infections (HP:0002841)2.28379170
72Periodontitis (HP:0000704)2.28231974
73Colitis (HP:0002583)2.28209586
74Pathologic fracture (HP:0002756)2.26837425
75Facial diplegia (HP:0001349)2.25213032
76Prolonged bleeding time (HP:0003010)2.22084477
77Stomatitis (HP:0010280)2.20182720
78Pulmonary infiltrates (HP:0002113)2.19111871
79Prolonged partial thromboplastin time (HP:0003645)2.17346778
80Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)2.16813387
81Abnormality of the middle phalanges of the toes (HP:0010183)2.14220665
82Urticaria (HP:0001025)2.14151257
83Abnormality of B cell number (HP:0010975)2.13687238
84B lymphocytopenia (HP:0010976)2.13687238
85Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.10092724
86Apathy (HP:0000741)2.08719967
87Recurrent viral infections (HP:0004429)2.06384199
88Delusions (HP:0000746)2.06150051
89Epistaxis (HP:0000421)2.05701467
90Dementia (HP:0000726)2.05196535
91Steatorrhea (HP:0002570)2.04531116
92Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.03636199
93Multiple enchondromatosis (HP:0005701)2.01825979
94Mutism (HP:0002300)2.00907307
95Cellulitis (HP:0100658)2.00037290
96Keratoconjunctivitis sicca (HP:0001097)1.98648284
97Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.98418249
98Tetraparesis (HP:0002273)1.97422664
99Mesangial abnormality (HP:0001966)1.97288084
100Petechiae (HP:0000967)1.96835337
101Thick nail (HP:0001805)1.96674395
102Neuronal loss in central nervous system (HP:0002529)1.96096184
103Increased serum ferritin (HP:0003281)1.95743502
104T lymphocytopenia (HP:0005403)1.95526284
105Bone pain (HP:0002653)1.94749544
106Xanthomatosis (HP:0000991)1.93345832
107Stomach cancer (HP:0012126)1.93085252
108J-shaped sella turcica (HP:0002680)1.92477583
109Autoimmune thrombocytopenia (HP:0001973)1.91447307
110Deep venous thrombosis (HP:0002625)1.91128171
111Chronic mucocutaneous candidiasis (HP:0002728)1.90818561
112Recurrent cutaneous fungal infections (HP:0011370)1.90818561
113Arthropathy (HP:0003040)1.90291072
114Abnormality of the vasculature of the conjunctiva (HP:0008054)1.89708214
115Hematochezia (HP:0002573)1.88762332
116Asymmetric septal hypertrophy (HP:0001670)1.88575053
117Esophageal varix (HP:0002040)1.87857858
118Osteomyelitis (HP:0002754)1.87437359
119Recurrent pneumonia (HP:0006532)1.87369566
120Abnormality of iron homeostasis (HP:0011031)1.87345947
121Interstitial pulmonary disease (HP:0006530)1.87240333
122Premature loss of primary teeth (HP:0006323)1.86452254
123Amyloidosis (HP:0011034)1.85552224
124Intrahepatic cholestasis (HP:0001406)1.84803181
125Thoracic kyphosis (HP:0002942)1.83002124
126Gastrointestinal infarctions (HP:0005244)1.82057476
127Generalized aminoaciduria (HP:0002909)1.81503414
128Purpura (HP:0000979)1.80675610
129Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.80563478
130Elevated erythrocyte sedimentation rate (HP:0003565)1.80382085
131Meningitis (HP:0001287)1.78605007
132Abnormality of the pleura (HP:0002103)1.78588290
133Inflammation of the large intestine (HP:0002037)1.77652250
134Keratoconjunctivitis (HP:0001096)1.77390059
135Albinism (HP:0001022)1.77334961
136Poor head control (HP:0002421)1.76743551
137Abnormality of pyrimidine metabolism (HP:0004353)1.76340552
138Cholelithiasis (HP:0001081)1.75659538
139Failure to thrive in infancy (HP:0001531)1.74268040
140Personality changes (HP:0000751)1.73320461
141Abnormality of T cell number (HP:0011839)1.71494899
142Progressive neurologic deterioration (HP:0002344)1.71400237
143Enlarged epiphyses (HP:0010580)1.71045798
144Fat malabsorption (HP:0002630)1.70770762
145Nuclear cataract (HP:0100018)1.69916502
146Symptomatic seizures (HP:0011145)1.69767980
147Prolonged neonatal jaundice (HP:0006579)1.69297199
148Amaurosis fugax (HP:0100576)1.69286295
149Increased CSF protein (HP:0002922)1.65136183

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K107.77470452
2PDK25.72647917
3MAP3K144.70351365
4BLK4.36843920
5TYK23.81809909
6NME23.41233670
7ACVR1B3.14993007
8TGFBR23.06632796
9IRAK32.90096072
10GRK72.76821676
11NEK92.34398486
12IRAK42.28266928
13CAMKK22.16681450
14IKBKB1.99295229
15TBK11.89171155
16EIF2AK21.81440249
17EPHB11.72588352
18CLK11.70708158
19IKBKE1.66525437
20ERN11.63408471
21TEC1.63237291
22BTK1.49218882
23BMPR21.46071081
24FES1.46012937
25MAP3K131.40391840
26NEK61.40172037
27PDPK11.39094279
28JAK11.32423535
29DDR21.31196646
30RIPK41.30116728
31CSF1R1.28287626
32MAP4K11.27746780
33DMPK1.25450821
34PIM21.23883779
35STK101.17398510
36LIMK11.16970827
37LYN1.15803243
38MAP3K21.15447898
39PDK11.15345296
40HCK1.15152508
41MAP2K31.14672570
42TXK1.11469754
43MAP3K111.11256492
44CHUK1.09547305
45TESK21.05926805
46LCK1.05184278
47SYK1.03417252
48CSK1.02064891
49ERBB40.98655798
50KSR20.96613601
51TRPM70.96145506
52TAOK30.90356217
53PBK0.89901469
54JAK20.89718532
55MOS0.88192721
56MAP3K80.86832162
57YES10.86029111
58TAOK20.85129074
59ERBB30.83714843
60MAP3K30.82425656
61CDC42BPA0.81148495
62MST40.80158351
63PIM10.77942222
64ZAP700.76962899
65BMX0.76649757
66PIK3CG0.75638830
67SGK30.75616390
68KIT0.74667351
69JAK30.74586320
70IGF1R0.71318779
71PKN10.71175419
72PRKG20.70484009
73ADRBK20.66773979
74PRKCD0.64728314
75IRAK20.64456694
76EGFR0.63848818
77ABL20.62251442
78MAPK120.61079166
79PRPF4B0.60980979
80FGR0.59758075
81MST1R0.58981129
82ARAF0.58480096
83EPHA30.58232272
84ABL10.55706545
85GRK50.55137576
86MAPK40.53637230
87EIF2AK30.53054574
88MARK30.52795682
89CAMKK10.51441991
90RIPK10.50397962
91MAP3K50.48987633
92MAPKAPK20.48765861
93CAMK40.46990886
94ITK0.46949600
95SIK20.46817189
96RPS6KA10.46044367
97MET0.45093670
98CAMK1D0.44229160
99MAPK70.43680673
100PAK40.43126294
101MAP3K10.41118270
102GSK3A0.41112888
103RPS6KL10.39975982
104RPS6KC10.39975982
105FGFR30.39557300
106EEF2K0.39328696
107CDK60.39025652
108INSR0.38554795
109MAP2K20.37123959
110FYN0.36329501
111ALK0.34789655
112ERBB20.34482578
113RPS6KA60.34038346
114PRKACB0.33873557
115SCYL20.33865960
116KSR10.32884827
117PRKACG0.32705619
118CAMK2G0.32361679
119CAMK1G0.31646065
120IRAK10.31263372
121PRKG10.30498490
122STK240.30331064
123CAMK2D0.29269086
124RPS6KA20.28352650
125MAPK90.28006482
126MAP3K60.27082823
127EIF2AK10.24697670
128PTK2B0.24544192
129MATK0.24516316
130PRKD10.23709155
131PTK60.23307239
132HIPK20.23146492
133INSRR0.23125939
134MAPK30.23109572
135TTN0.20969191
136MAPK150.20682839
137SGK20.20314919
138PTK20.19402428

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051506.55762014
2Complement and coagulation cascades_Homo sapiens_hsa046103.46101797
3Pertussis_Homo sapiens_hsa051332.83191899
4Leishmaniasis_Homo sapiens_hsa051402.66071456
5Glycosaminoglycan degradation_Homo sapiens_hsa005312.54463415
6Lysosome_Homo sapiens_hsa041422.48821031
7Osteoclast differentiation_Homo sapiens_hsa043802.30741508
8Other glycan degradation_Homo sapiens_hsa005112.27198215
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.13715987
10Collecting duct acid secretion_Homo sapiens_hsa049662.06959566
11Allograft rejection_Homo sapiens_hsa053302.03784697
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.02515486
13Sulfur metabolism_Homo sapiens_hsa009201.91894635
14Legionellosis_Homo sapiens_hsa051341.91890370
15Tuberculosis_Homo sapiens_hsa051521.88627078
16Phagosome_Homo sapiens_hsa041451.81341638
17Rheumatoid arthritis_Homo sapiens_hsa053231.75823057
18NF-kappa B signaling pathway_Homo sapiens_hsa040641.74278982
19NOD-like receptor signaling pathway_Homo sapiens_hsa046211.74114305
20Graft-versus-host disease_Homo sapiens_hsa053321.70263353
21* Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.70049357
22* Chemokine signaling pathway_Homo sapiens_hsa040621.68307660
23Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.60791175
24Malaria_Homo sapiens_hsa051441.58093192
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.56495773
26B cell receptor signaling pathway_Homo sapiens_hsa046621.53584435
27Arachidonic acid metabolism_Homo sapiens_hsa005901.50562422
28Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.49990105
29Vibrio cholerae infection_Homo sapiens_hsa051101.49036789
30Fructose and mannose metabolism_Homo sapiens_hsa000511.47307042
31Galactose metabolism_Homo sapiens_hsa000521.44808177
32Asthma_Homo sapiens_hsa053101.40095023
33Salmonella infection_Homo sapiens_hsa051321.39599080
34Pentose phosphate pathway_Homo sapiens_hsa000301.34962422
35Measles_Homo sapiens_hsa051621.34462846
36Prion diseases_Homo sapiens_hsa050201.34390321
37Hematopoietic cell lineage_Homo sapiens_hsa046401.28529427
38Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.28510080
39Toxoplasmosis_Homo sapiens_hsa051451.25642074
40Autoimmune thyroid disease_Homo sapiens_hsa053201.18417880
41Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.16925150
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.09581342
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.08510519
44ABC transporters_Homo sapiens_hsa020101.04693238
45Shigellosis_Homo sapiens_hsa051311.04485942
46Caffeine metabolism_Homo sapiens_hsa002321.02356084
47Pentose and glucuronate interconversions_Homo sapiens_hsa000401.02076245
48Jak-STAT signaling pathway_Homo sapiens_hsa046300.98871089
49Apoptosis_Homo sapiens_hsa042100.97426170
50Primary bile acid biosynthesis_Homo sapiens_hsa001200.94894297
51Histidine metabolism_Homo sapiens_hsa003400.92094848
52Influenza A_Homo sapiens_hsa051640.90238105
53Renin-angiotensin system_Homo sapiens_hsa046140.90186519
54RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83181194
55African trypanosomiasis_Homo sapiens_hsa051430.82478034
56Type I diabetes mellitus_Homo sapiens_hsa049400.82261190
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.78837627
58Viral myocarditis_Homo sapiens_hsa054160.77641227
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77278009
60TNF signaling pathway_Homo sapiens_hsa046680.75504140
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73219476
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.72561022
63Glutathione metabolism_Homo sapiens_hsa004800.72522379
64Herpes simplex infection_Homo sapiens_hsa051680.71283316
65Synaptic vesicle cycle_Homo sapiens_hsa047210.70036442
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67045068
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.66979784
68HIF-1 signaling pathway_Homo sapiens_hsa040660.65899251
69Primary immunodeficiency_Homo sapiens_hsa053400.65899029
70Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.63317633
71Chemical carcinogenesis_Homo sapiens_hsa052040.61988636
72Nitrogen metabolism_Homo sapiens_hsa009100.61820987
73Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60110163
74Hepatitis C_Homo sapiens_hsa051600.59561882
75AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.59003231
76PPAR signaling pathway_Homo sapiens_hsa033200.58528586
77Amoebiasis_Homo sapiens_hsa051460.58477484
78Non-homologous end-joining_Homo sapiens_hsa034500.57949633
79Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57408807
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56739920
81Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56357336
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55334939
83beta-Alanine metabolism_Homo sapiens_hsa004100.55245999
84Sphingolipid metabolism_Homo sapiens_hsa006000.52679273
85Arginine biosynthesis_Homo sapiens_hsa002200.50603963
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.49661649
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49338900
88Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48977589
89Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48415239
90Mineral absorption_Homo sapiens_hsa049780.48176022
91Hepatitis B_Homo sapiens_hsa051610.47680443
92Platelet activation_Homo sapiens_hsa046110.47580330
93Glycerolipid metabolism_Homo sapiens_hsa005610.47286392
94Carbon metabolism_Homo sapiens_hsa012000.46150908
95Antigen processing and presentation_Homo sapiens_hsa046120.45272142
96Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45141475
97Steroid biosynthesis_Homo sapiens_hsa001000.43746247
98Bladder cancer_Homo sapiens_hsa052190.42057103
99T cell receptor signaling pathway_Homo sapiens_hsa046600.40517081
100Tryptophan metabolism_Homo sapiens_hsa003800.39621465
101Starch and sucrose metabolism_Homo sapiens_hsa005000.37270285
102Folate biosynthesis_Homo sapiens_hsa007900.37114940
103Ether lipid metabolism_Homo sapiens_hsa005650.36608412
104Fatty acid biosynthesis_Homo sapiens_hsa000610.35617542
105Vitamin B6 metabolism_Homo sapiens_hsa007500.34283563
106Fatty acid degradation_Homo sapiens_hsa000710.34048141
107Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33440755
108Systemic lupus erythematosus_Homo sapiens_hsa053220.32209998
109Retinol metabolism_Homo sapiens_hsa008300.31214408
110Phenylalanine metabolism_Homo sapiens_hsa003600.30453387
111Type II diabetes mellitus_Homo sapiens_hsa049300.30009664
112Chronic myeloid leukemia_Homo sapiens_hsa052200.28864421
113Acute myeloid leukemia_Homo sapiens_hsa052210.27563019
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.27514810
115Vitamin digestion and absorption_Homo sapiens_hsa049770.26860474
116Peroxisome_Homo sapiens_hsa041460.26593869
117Fat digestion and absorption_Homo sapiens_hsa049750.25424608
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.23158091
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.21693017
120Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.21067976
1212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.20146856
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.20062956
123Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.19930002
124Pancreatic cancer_Homo sapiens_hsa052120.19310558
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.18849738
126Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.17813550
127Endocytosis_Homo sapiens_hsa041440.17251048
128Insulin resistance_Homo sapiens_hsa049310.16012647

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