CCL4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of chemokine biosynthetic process (GO:0045080)6.30394361
2cytidine deamination (GO:0009972)6.23224216
3cytidine metabolic process (GO:0046087)6.23224216
4cytidine catabolic process (GO:0006216)6.23224216
5regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.13798163
6DNA deamination (GO:0045006)5.67649015
7response to peptidoglycan (GO:0032494)5.64765600
8pyrimidine ribonucleoside catabolic process (GO:0046133)5.50848338
9regulation of chemokine biosynthetic process (GO:0045073)5.30022525
10positive regulation by symbiont of host defense response (GO:0052509)5.24087179
11modulation by symbiont of host defense response (GO:0052031)5.24087179
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.24087179
13modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.24087179
14positive regulation by organism of defense response of other organism involved in symbiotic interact5.24087179
15modulation by symbiont of host immune response (GO:0052553)5.24087179
16negative regulation of interleukin-12 production (GO:0032695)5.18158333
17cellular response to exogenous dsRNA (GO:0071360)5.13128400
18lipopolysaccharide-mediated signaling pathway (GO:0031663)4.95645547
19regulation of T-helper 1 cell differentiation (GO:0045625)4.81966452
20positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)4.70803740
21regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)4.70803740
22eosinophil chemotaxis (GO:0048245)4.68024190
23cellular response to interferon-beta (GO:0035458)4.67006627
24positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.57301748
25neutrophil activation involved in immune response (GO:0002283)4.56651459
26positive regulation of interferon-alpha production (GO:0032727)4.52519979
27regulation of interleukin-2 biosynthetic process (GO:0045076)4.45060446
28positive regulation of heat generation (GO:0031652)4.43248933
29regulation of fever generation (GO:0031620)4.40359193
30positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.34234358
31negative regulation of interleukin-17 production (GO:0032700)4.30879222
32positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.30734238
33regulation of interferon-alpha production (GO:0032647)4.28779637
34positive regulation of natural killer cell mediated immunity (GO:0002717)4.28671884
35myeloid dendritic cell differentiation (GO:0043011)4.25956396
36positive regulation of heterotypic cell-cell adhesion (GO:0034116)4.25064902
37regulation of vitamin D biosynthetic process (GO:0060556)4.23343632
38negative regulation of viral genome replication (GO:0045071)4.22065372
39positive regulation of defense response to virus by host (GO:0002230)4.15447091
40positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)4.13656656
41eosinophil migration (GO:0072677)4.13426241
42positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.05659167
43hydrogen peroxide biosynthetic process (GO:0050665)4.05559194
44antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.04470950
45positive regulation of gamma-delta T cell activation (GO:0046645)3.94910585
46regulation of natural killer cell mediated immunity (GO:0002715)3.94577123
47regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.94577123
48response to interferon-beta (GO:0035456)3.93270480
49granulocyte activation (GO:0036230)3.92880727
50macrophage activation involved in immune response (GO:0002281)3.91165783
51cellular response to type I interferon (GO:0071357)3.91109985
52type I interferon signaling pathway (GO:0060337)3.91109985
53regulation of chronic inflammatory response (GO:0002676)3.88851170
54regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.87756343
55cellular response to interleukin-15 (GO:0071350)3.86011213
56response to type I interferon (GO:0034340)3.85744411
57positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.83629271
58regulation of T cell tolerance induction (GO:0002664)3.83395342
59regulation of cytokine secretion involved in immune response (GO:0002739)3.81922007
60NIK/NF-kappaB signaling (GO:0038061)3.81848834
61regulation of activation of Janus kinase activity (GO:0010533)3.81435419
62respiratory burst (GO:0045730)3.80229204
63regulation of mononuclear cell migration (GO:0071675)3.79686680
64CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.77045684
65lymphocyte chemotaxis (GO:0048247)3.76588629
66regulation of interleukin-17 production (GO:0032660)3.75298390
67production of molecular mediator involved in inflammatory response (GO:0002532)3.74772755
68regulation of vitamin metabolic process (GO:0030656)3.74529323
69T cell migration (GO:0072678)3.73509029
70macrophage chemotaxis (GO:0048246)3.71298910
71myeloid dendritic cell activation (GO:0001773)3.70149715
72regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.70048944
73superoxide anion generation (GO:0042554)3.68064867
74regulation of podosome assembly (GO:0071801)3.67325940
75response to protozoan (GO:0001562)3.65469672
76positive regulation of type 2 immune response (GO:0002830)3.64878585
77monocyte chemotaxis (GO:0002548)3.62237404
78regulation of interferon-beta biosynthetic process (GO:0045357)3.58789400
79regulation of T cell cytokine production (GO:0002724)3.58502151
80positive regulation of NF-kappaB import into nucleus (GO:0042346)3.57890709
81reactive oxygen species biosynthetic process (GO:1903409)3.57657882
82positive regulation of tolerance induction (GO:0002645)3.56697155
83regulation of heterotypic cell-cell adhesion (GO:0034114)3.54425824
84positive regulation of interleukin-1 beta secretion (GO:0050718)3.53894748
85response to host immune response (GO:0052572)3.53309281
86response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.53309281
87response to interleukin-15 (GO:0070672)3.50782629
88cellular response to interferon-alpha (GO:0035457)3.49063283
89defense response to protozoan (GO:0042832)3.46851779
90regulation of interleukin-12 biosynthetic process (GO:0045075)3.44187072
91positive regulation of T cell cytokine production (GO:0002726)3.42432200
92negative regulation of cytokine production involved in immune response (GO:0002719)3.41436725
93positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.41386302
94negative regulation of amino acid transport (GO:0051956)3.41300921
95positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.34839687
96cellular response to nicotine (GO:0071316)3.34772900
97positive regulation of nitric oxide biosynthetic process (GO:0045429)3.34525794
98positive regulation of chemokine production (GO:0032722)3.34139592
99immunoglobulin mediated immune response (GO:0016064)3.33923858
100regulation of leukocyte mediated cytotoxicity (GO:0001910)3.32217821
101myeloid cell activation involved in immune response (GO:0002275)3.31742409
102sarcoplasmic reticulum calcium ion transport (GO:0070296)3.31613620
103positive regulation of interferon-beta production (GO:0032728)3.31067052
104regulation of growth of symbiont in host (GO:0044126)3.30928282
105negative regulation of growth of symbiont in host (GO:0044130)3.30928282
106negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.30928282
107modulation of growth of symbiont involved in interaction with host (GO:0044144)3.30928282
108regulation of heat generation (GO:0031650)3.30621401
109positive regulation of interleukin-12 production (GO:0032735)3.29879176
110positive regulation of B cell mediated immunity (GO:0002714)3.28984181
111positive regulation of immunoglobulin mediated immune response (GO:0002891)3.28984181
112detection of molecule of bacterial origin (GO:0032490)3.28573196
113positive regulation of interleukin-10 production (GO:0032733)3.28374360
114positive regulation of interleukin-1 secretion (GO:0050716)3.28300663
115microglial cell activation (GO:0001774)3.27941098
116positive regulation of lymphocyte apoptotic process (GO:0070230)3.27508417
117neutrophil chemotaxis (GO:0030593)3.26369418
118* positive regulation of lymphocyte migration (GO:2000403)3.26047779
119positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.25584620
120positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610813.25495100
121positive regulation of cytokine biosynthetic process (GO:0042108)3.25382913
122regulation of T cell chemotaxis (GO:0010819)3.24910797
123positive regulation of T cell chemotaxis (GO:0010820)3.24910797
124response to interferon-alpha (GO:0035455)3.23955461
125* regulation of lymphocyte chemotaxis (GO:1901623)3.23678012
126regulation of cell killing (GO:0031341)3.18665107
127regulation of interleukin-12 production (GO:0032655)3.18308731
128* negative regulation by host of viral transcription (GO:0043922)3.17789104
129negative regulation of interleukin-2 production (GO:0032703)3.17771854
130regulation of immunoglobulin secretion (GO:0051023)3.17730157
131neutrophil migration (GO:1990266)3.17509373
132regulation of interferon-gamma biosynthetic process (GO:0045072)3.17202875
133positive regulation of humoral immune response (GO:0002922)3.17111684
134positive regulation of interleukin-17 production (GO:0032740)3.15914915
135positive regulation of mast cell activation involved in immune response (GO:0033008)3.15550472
136positive regulation of mast cell degranulation (GO:0043306)3.15550472
137regulation of tolerance induction (GO:0002643)3.14544582
138* positive regulation of calcium-mediated signaling (GO:0050850)3.14000045
139positive regulation of monocyte chemotaxis (GO:0090026)3.13842217
140negative regulation of production of molecular mediator of immune response (GO:0002701)3.12211379
141regulation of viral genome replication (GO:0045069)3.09251034
142* negative regulation of viral process (GO:0048525)3.05700283
143regulation of interleukin-1 beta secretion (GO:0050706)3.03291259
144* regulation of lymphocyte migration (GO:2000401)3.03013613
145interferon-gamma-mediated signaling pathway (GO:0060333)3.02938437
146germinal center formation (GO:0002467)3.01351853
147negative regulation of T cell activation (GO:0050868)3.00389279
148positive regulation of cell killing (GO:0031343)2.99333416
149positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.98004594
150regulation of B cell receptor signaling pathway (GO:0050855)2.95862565
151positive regulation of T cell apoptotic process (GO:0070234)2.95423635
152negative regulation of T cell mediated immunity (GO:0002710)2.94632726
153negative regulation of cell killing (GO:0031342)2.94405478
154negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.94405478
155positive regulation of lymphocyte mediated immunity (GO:0002708)2.91667358

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human8.11943587
2IRF8_21731497_ChIP-ChIP_J774_Mouse8.00125859
3* BP1_19119308_ChIP-ChIP_Hs578T_Human5.84978255
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse5.05808449
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.97641201
6* IRF8_27001747_Chip-Seq_BMDM_Mouse4.44063498
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.98024698
8* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.91416824
9* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.66948680
10* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.66174538
11Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.44080972
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.06507730
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.93742996
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.92581519
15STAT4_19710469_ChIP-ChIP_TH1__Mouse2.91727234
16SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.73756491
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.73365504
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.58924402
19NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.09061897
20STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.03546921
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.91058615
22PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.85792702
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.82582682
24* SPI1_23547873_ChIP-Seq_NB4_Human1.78573573
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.77667643
26* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.72796151
27BRD4_27068464_Chip-Seq_AML-cells_Mouse1.70667951
28* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.68806193
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.67459840
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.66208784
31VDR_24787735_ChIP-Seq_THP-1_Human1.65313387
32PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.64885340
33MAF_26560356_Chip-Seq_TH2_Human1.63766531
34THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.55586557
35TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.53636816
36CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.49836490
37* PU_27001747_Chip-Seq_BMDM_Mouse1.48349276
38RUNX_20019798_ChIP-Seq_JUKART_Human1.47537137
39SMAD_19615063_ChIP-ChIP_OVARY_Human1.46406675
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46289603
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.43488244
42MYB_26560356_Chip-Seq_TH2_Human1.43467974
43STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.42628030
44IKZF1_21737484_ChIP-ChIP_HCT116_Human1.41000464
45VDR_24763502_ChIP-Seq_THP-1_Human1.35275241
46RUNX1_22412390_ChIP-Seq_EML_Mouse1.34288247
47* CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.33672191
48* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.32313413
49LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.28702010
50FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.26782891
51NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.25332119
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22260442
53SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.21862816
54GATA3_26560356_Chip-Seq_TH2_Human1.20400144
55SCL_19346495_ChIP-Seq_HPC-7_Human1.18256036
56* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.15942466
57SPI1_23127762_ChIP-Seq_K562_Human1.15049118
58LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.14586288
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11474506
60* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.08925164
61MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.08398530
62GATA3_27048872_Chip-Seq_THYMUS_Human1.08321063
63EGR1_23403033_ChIP-Seq_LIVER_Mouse1.05824918
64NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.05295657
65NRF2_20460467_ChIP-Seq_MEFs_Mouse1.05295657
66GATA1_22025678_ChIP-Seq_K562_Human1.03602453
67GATA2_22383799_ChIP-Seq_G1ME_Mouse1.02556167
68GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00973237
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96363260
70* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95870200
71SOX2_20726797_ChIP-Seq_SW620_Human0.95414211
72EGR1_19032775_ChIP-ChIP_M12_Human0.95275838
73SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94474646
74CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.94466148
75TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.93779572
76MAF_26560356_Chip-Seq_TH1_Human0.91044106
77MYB_26560356_Chip-Seq_TH1_Human0.90996947
78NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87328074
79GATA2_21666600_ChIP-Seq_HMVEC_Human0.85656082
80BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.84649057
81TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83863843
82HOXB4_20404135_ChIP-ChIP_EML_Mouse0.83782778
83VDR_21846776_ChIP-Seq_THP-1_Human0.83735204
84VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.83534817
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.82218072
86SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.79823309
87STAT1_20625510_ChIP-Seq_HELA_Human0.79017022
88STAT6_21828071_ChIP-Seq_BEAS2B_Human0.79005312
89CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.78487408
90JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.76180228
91FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.75633535
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75307755
93ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.74240129
94TP63_17297297_ChIP-ChIP_HaCaT_Human0.72908818
95TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.72596291
96MYC_22102868_ChIP-Seq_BL_Human0.71592580
97CDX2_19796622_ChIP-Seq_MESCs_Mouse0.71574612
98BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.71541321
99CJUN_26792858_Chip-Seq_BT549_Human0.70143354
100JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.69619459
101CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.69266521
102MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.68609318
103RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.68414564
104BCL6_27268052_Chip-Seq_Bcells_Human0.68278487
105SA1_27219007_Chip-Seq_Bcells_Human0.67195881
106GATA1_19941827_ChIP-Seq_MEL_Mouse0.66790194
107KDM2B_26808549_Chip-Seq_DND41_Human0.66214338
108E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.66192383
109SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.65914786
110SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.65914786
111BCOR_27268052_Chip-Seq_Bcells_Human0.65744933
112UTX_26944678_Chip-Seq_JUKART_Human0.64472986
113GATA3_26560356_Chip-Seq_TH1_Human0.64115686
114TRIM28_21343339_ChIP-Seq_HEK293_Human0.63633072
115TFEB_21752829_ChIP-Seq_HELA_Human0.62065107
116TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.61956065
117CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.61099321
118* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.60947662
119EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.60120373
120ELF1_20517297_ChIP-Seq_JURKAT_Human0.58703622
121CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.58349442
122PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.58066838
123KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.57782339
124KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.57782339
125PU1_27457419_Chip-Seq_LIVER_Mouse0.57680158
126KAP1_22055183_ChIP-Seq_ESCs_Mouse0.57200908
127CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.57138235
128SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.56180401
129* SPI1_20517297_ChIP-Seq_HL60_Human0.55754205
130SALL4_22934838_ChIP-ChIP_CD34+_Human0.55497548
131GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.54865530
132SMAD1_18555785_Chip-Seq_ESCs_Mouse0.54397855
133STAT3_18555785_Chip-Seq_ESCs_Mouse0.53453384
134GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.50939607
135SMRT_27268052_Chip-Seq_Bcells_Human0.50580453

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006082_CNS_inflammation5.33636889
2MP0009785_altered_susceptibility_to5.10362515
3MP0001835_abnormal_antigen_presentation4.49861557
4MP0003436_decreased_susceptibility_to4.43160371
5MP0002148_abnormal_hypersensitivity_rea4.43083144
6MP0003724_increased_susceptibility_to4.18406613
7MP0005000_abnormal_immune_tolerance3.79070268
8MP0002419_abnormal_innate_immunity3.38640311
9MP0005025_abnormal_response_to3.38024858
10MP0005671_abnormal_response_to2.95629711
11MP0003303_peritoneal_inflammation2.95322599
12MP0009764_decreased_sensitivity_to2.72498276
13MP0002723_abnormal_immune_serum2.65534411
14MP0002452_abnormal_antigen_presenting2.58415901
15MP0001800_abnormal_humoral_immune2.45874111
16MP0001533_abnormal_skeleton_physiology2.44570488
17MP0001853_heart_inflammation2.36807228
18MP0002006_tumorigenesis2.35711999
19MP0004947_skin_inflammation2.25694186
20MP0001790_abnormal_immune_system2.20947813
21MP0005387_immune_system_phenotype2.20947813
22MP0001819_abnormal_immune_cell2.17635503
23MP0002420_abnormal_adaptive_immunity2.14698006
24MP0000685_abnormal_immune_system2.10217445
25MP0004510_myositis2.10121901
26MP0005464_abnormal_platelet_physiology2.05078696
27MP0008469_abnormal_protein_level1.98351851
28MP0002405_respiratory_system_inflammati1.96310860
29MP0001845_abnormal_inflammatory_respons1.95598761
30MP0005058_abnormal_lysosome_morphology1.91607812
31MP0009333_abnormal_splenocyte_physiolog1.87116228
32MP0003448_altered_tumor_morphology1.85942508
33MP0003075_altered_response_to1.83612359
34MP0000569_abnormal_digit_pigmentation1.80257186
35MP0000343_altered_response_to1.65122936
36MP0005166_decreased_susceptibility_to1.62311834
37MP0010155_abnormal_intestine_physiology1.58836190
38MP0002138_abnormal_hepatobiliary_system1.56408417
39MP0003186_abnormal_redox_activity1.54208726
40MP0000858_altered_metastatic_potential1.52228842
41MP0009278_abnormal_bone_marrow1.52145220
42MP0003690_abnormal_glial_cell1.49987867
43MP0000716_abnormal_immune_system1.45824741
44MP0005167_abnormal_blood-brain_barrier1.45624335
45MP0002139_abnormal_hepatobiliary_system1.41807907
46MP0002877_abnormal_melanocyte_morpholog1.41303642
47MP0003172_abnormal_lysosome_physiology1.38690667
48MP0002998_abnormal_bone_remodeling1.34312752
49MP0002398_abnormal_bone_marrow1.31295316
50MP0003806_abnormal_nucleotide_metabolis1.25914103
51MP0005164_abnormal_response_to1.25812888
52MP0003195_calcinosis1.24063106
53MP0003191_abnormal_cellular_cholesterol1.23006208
54MP0005310_abnormal_salivary_gland1.17452606
55MP0005390_skeleton_phenotype1.16232936
56MP0002933_joint_inflammation1.16023428
57MP0002429_abnormal_blood_cell1.15451383
58MP0003828_pulmonary_edema1.13925460
59MP0000604_amyloidosis1.08552365
60MP0000703_abnormal_thymus_morphology1.05316966
61MP0000689_abnormal_spleen_morphology1.04618060
62MP0006054_spinal_hemorrhage1.02229566
63MP0004782_abnormal_surfactant_physiolog1.01605532
64MP0009763_increased_sensitivity_to1.01221643
65MP0008004_abnormal_stomach_pH1.01186182
66MP0002722_abnormal_immune_system0.97602141
67MP0005397_hematopoietic_system_phenotyp0.95341597
68MP0001545_abnormal_hematopoietic_system0.95341597
69MP0002277_abnormal_respiratory_mucosa0.95064598
70MP0005451_abnormal_body_composition0.87604097
71MP0001851_eye_inflammation0.86884901
72MP0002332_abnormal_exercise_endurance0.85157645
73MP0010307_abnormal_tumor_latency0.84135448
74MP0003453_abnormal_keratinocyte_physiol0.83754084
75MP0001501_abnormal_sleep_pattern0.82840905
76MP0009840_abnormal_foam_cell0.81772497
77MP0000920_abnormal_myelination0.80565033
78MP0003646_muscle_fatigue0.79563144
79MP0004883_abnormal_blood_vessel0.77438151
80MP0003656_abnormal_erythrocyte_physiolo0.76976116
81MP0005535_abnormal_body_temperature0.75099413
82MP0004742_abnormal_vestibular_system0.72230583
83MP0002163_abnormal_gland_morphology0.68664159
84MP0000249_abnormal_blood_vessel0.68506168
85MP0001919_abnormal_reproductive_system0.66847504
86MP0005165_increased_susceptibility_to0.63358198
87MP0002136_abnormal_kidney_physiology0.63208525
88MP0009765_abnormal_xenobiotic_induced0.60735870
89MP0001542_abnormal_bone_strength0.59751070
90MP0003763_abnormal_thymus_physiology0.57267336
91MP0001958_emphysema0.57205227
92MP0001873_stomach_inflammation0.56975008
93MP0004381_abnormal_hair_follicle0.56835262
94MP0003795_abnormal_bone_structure0.54287242
95MP0003183_abnormal_peptide_metabolism0.53748198
96MP0002693_abnormal_pancreas_physiology0.53714467
97MP0001727_abnormal_embryo_implantation0.53417894
98MP0010386_abnormal_urinary_bladder0.51205475
99MP0001663_abnormal_digestive_system0.50876505
100MP0002090_abnormal_vision0.49030904
101MP0005647_abnormal_sex_gland0.47851255
102MP0002254_reproductive_system_inflammat0.47723404
103MP0005408_hypopigmentation0.47546081
104MP0002166_altered_tumor_susceptibility0.46285323
105MP0008260_abnormal_autophagy0.45524858
106MP0003300_gastrointestinal_ulcer0.45318893
107MP0008873_increased_physiological_sensi0.43878014
108MP0010352_gastrointestinal_tract_polyps0.43056386
109MP0005319_abnormal_enzyme/_coenzyme0.43002155
110MP0005171_absent_coat_pigmentation0.40237786
111MP0000371_diluted_coat_color0.39672526
112MP0000609_abnormal_liver_physiology0.37509863
113MP0009642_abnormal_blood_homeostasis0.35210515
114MP0000490_abnormal_crypts_of0.34698033
115MP0003045_fibrosis0.34202508
116MP0005584_abnormal_enzyme/coenzyme_acti0.34062965
117MP0003866_abnormal_defecation0.32811359

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)7.69993817
2Eczematoid dermatitis (HP:0000976)7.27214158
3Recurrent bacterial skin infections (HP:0005406)6.92032618
4Recurrent gram-negative bacterial infections (HP:0005420)6.79979037
5Stomatitis (HP:0010280)6.48654787
6Elevated erythrocyte sedimentation rate (HP:0003565)6.03611744
7Mediastinal lymphadenopathy (HP:0100721)5.75077849
8Systemic lupus erythematosus (HP:0002725)5.53849336
9Abnormality of macrophages (HP:0004311)5.18009130
10Retrobulbar optic neuritis (HP:0100654)4.47116969
11Optic neuritis (HP:0100653)4.47116969
12Interstitial pulmonary disease (HP:0006530)4.36759575
13Orchitis (HP:0100796)4.36655697
14Myositis (HP:0100614)4.28369854
15Gingivitis (HP:0000230)4.25306120
16Recurrent skin infections (HP:0001581)4.20873468
17Autoimmune thrombocytopenia (HP:0001973)4.17841116
18Abnormality of T cells (HP:0002843)4.10172520
19Basal ganglia calcification (HP:0002135)4.10066244
20Abnormal delayed hypersensitivity skin test (HP:0002963)4.00631292
21Chronic obstructive pulmonary disease (HP:0006510)3.89051475
22Obstructive lung disease (HP:0006536)3.89051475
23Vasculitis (HP:0002633)3.84316919
24Increased neuronal autofluorescent lipopigment (HP:0002074)3.75889579
25Recurrent fungal infections (HP:0002841)3.64146098
26Increased cerebral lipofuscin (HP:0011813)3.61405917
27Vacuolated lymphocytes (HP:0001922)3.53313164
28Encephalitis (HP:0002383)3.53236095
29Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.51800154
30Recurrent bronchitis (HP:0002837)3.45421262
31Increased IgM level (HP:0003496)3.42651093
32Axonal loss (HP:0003447)3.37045773
33Pulmonary infiltrates (HP:0002113)3.23677527
34Petechiae (HP:0000967)3.22008908
35Poor head control (HP:0002421)3.21485287
36Abnormality of eosinophils (HP:0001879)3.18529158
37Recurrent viral infections (HP:0004429)3.17879222
38IgG deficiency (HP:0004315)3.06137728
39Severe combined immunodeficiency (HP:0004430)3.05891652
40Purpura (HP:0000979)2.99544819
41Disinhibition (HP:0000734)2.97576799
42Eosinophilia (HP:0001880)2.92541516
43Hepatosplenomegaly (HP:0001433)2.88273861
44Combined immunodeficiency (HP:0005387)2.86132953
45Nausea (HP:0002018)2.84676561
46Pustule (HP:0200039)2.81988047
47Recurrent cutaneous fungal infections (HP:0011370)2.81413188
48Chronic mucocutaneous candidiasis (HP:0002728)2.81413188
49Urticaria (HP:0001025)2.80859821
50Glomerulonephritis (HP:0000099)2.78243345
51Prostate neoplasm (HP:0100787)2.76264930
52Hemorrhage of the eye (HP:0011885)2.72966500
53Abnormality of the pericardium (HP:0001697)2.71749425
54Periodontitis (HP:0000704)2.71056581
55Joint swelling (HP:0001386)2.69951889
56Aplastic anemia (HP:0001915)2.69939917
57Thick nail (HP:0001805)2.69374499
58Recurrent pneumonia (HP:0006532)2.67752737
59Porencephaly (HP:0002132)2.66606811
60Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.66120831
61Joint hemorrhage (HP:0005261)2.63722999
62Cellulitis (HP:0100658)2.63355847
63Meningitis (HP:0001287)2.61920771
64Nephritis (HP:0000123)2.60662953
65Polyneuropathy (HP:0001271)2.60404571
66Prolonged neonatal jaundice (HP:0006579)2.58403190
67Increased serum ferritin (HP:0003281)2.57955108
68Keratoconjunctivitis sicca (HP:0001097)2.53802393
69Hypergammaglobulinemia (HP:0010702)2.53526878
70Agnosia (HP:0010524)2.51402241
71Abnormality of liposaccharide metabolism (HP:0010968)2.51003582
72Abnormality of glycosphingolipid metabolism (HP:0004343)2.51003582
73Abnormality of glycolipid metabolism (HP:0010969)2.51003582
74Gingival bleeding (HP:0000225)2.50002878
75Tetraparesis (HP:0002273)2.49789824
76Thyroiditis (HP:0100646)2.48415829
77Granulocytopenia (HP:0001913)2.48118500
78Arterial thrombosis (HP:0004420)2.47794075
79Mutism (HP:0002300)2.44186677
80Abnormality of T cell physiology (HP:0011840)2.43926144
81Hypoproteinemia (HP:0003075)2.42825247
82Abnormality of the pleura (HP:0002103)2.40268554
83Pulmonary embolism (HP:0002204)2.39631410
84IgA deficiency (HP:0002720)2.37981205
85Alveolar cell carcinoma (HP:0006519)2.35801582
86Fused cervical vertebrae (HP:0002949)2.34065583
87Abnormality of T cell number (HP:0011839)2.32465172
88Hemoptysis (HP:0002105)2.31591078
89Recurrent lower respiratory tract infections (HP:0002783)2.31179697
90Keratoconjunctivitis (HP:0001096)2.30551262
91Lymphopenia (HP:0001888)2.30115714
92Abnormality of cells of the lymphoid lineage (HP:0012140)2.27102297
93Chronic otitis media (HP:0000389)2.23431062
94Lower limb hyperreflexia (HP:0002395)2.22245905
95Abnormality of polysaccharide metabolism (HP:0011012)2.21384591
96Abnormality of glycosaminoglycan metabolism (HP:0004371)2.21384591
97Abnormality of mucopolysaccharide metabolism (HP:0011020)2.21384591
98T lymphocytopenia (HP:0005403)2.20523277
99Abnormality of B cell number (HP:0010975)2.20427948
100Arthralgia (HP:0002829)2.19141567
101Pigmentary retinal degeneration (HP:0001146)2.17933494
102Glomerulopathy (HP:0100820)2.17710086
103Premature loss of primary teeth (HP:0006323)2.17344041
104Leukocytosis (HP:0001974)2.16870724
105Loss of speech (HP:0002371)2.16384299
106Agammaglobulinemia (HP:0004432)2.16366394
107Osteomyelitis (HP:0002754)2.15521898
108B lymphocytopenia (HP:0010976)2.13322695
109Progressive visual loss (HP:0000529)2.11390497
110Neoplasm of the tracheobronchial system (HP:0100552)2.10394345
111Oral leukoplakia (HP:0002745)2.09470421
112Bone pain (HP:0002653)2.07323570
113Chest pain (HP:0100749)2.04822759
114Autoimmune hemolytic anemia (HP:0001890)2.04562916
115Cleft eyelid (HP:0000625)2.03997894
116Anorexia (HP:0002039)2.03580232
117Chronic diarrhea (HP:0002028)2.03468667
118Acute hepatic failure (HP:0006554)2.03165414
119Abnormality of iron homeostasis (HP:0011031)1.96815746
120Parakeratosis (HP:0001036)1.96505280
121Lymphoma (HP:0002665)1.94634426
122Abnormality of the prostate (HP:0008775)1.94342149
123Bronchitis (HP:0012387)1.93420368
124Myocardial infarction (HP:0001658)1.93108381
125Episodic fever (HP:0001954)1.92878730
126Gangrene (HP:0100758)1.92417580
127Gastrointestinal infarctions (HP:0005244)1.92207748
128Dysostosis multiplex (HP:0000943)1.92176924
129Pathologic fracture (HP:0002756)1.90065290
130Pulmonary fibrosis (HP:0002206)1.89018702
131Mucopolysacchariduria (HP:0008155)1.87216131
132Urinary glycosaminoglycan excretion (HP:0003541)1.87216131
133Abnormality of the basal ganglia (HP:0002134)1.86672241
134Nasal polyposis (HP:0100582)1.85998931
135Upper motor neuron abnormality (HP:0002127)1.84790608
136Gastrointestinal stroma tumor (HP:0100723)1.84674185
137Memory impairment (HP:0002354)1.83638313
138Skin ulcer (HP:0200042)1.78434975
139Neoplasm of head and neck (HP:0012288)1.77087041
140Esophageal neoplasm (HP:0100751)1.77087041
141Micronodular cirrhosis (HP:0001413)1.74236093
142Segmental peripheral demyelination/remyelination (HP:0003481)1.73710877

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BLK5.31779813
2PBK5.22869759
3RIPK44.21519706
4MAP3K144.01972773
5TXK3.87841250
6TBK13.82174556
7IRAK32.95562457
8IRAK42.89297452
9MAP4K12.70345793
10IKBKE2.55867774
11IKBKB2.55451178
12TAOK22.46479266
13PIM22.28211301
14TYK22.13834575
15KDR2.11847342
16BMPR22.08235253
17JAK31.96090286
18MST41.80699741
19CSK1.80240856
20KIT1.73374656
21TAOK31.71850155
22MAP3K31.71759905
23DDR21.68141473
24ERN11.67975263
25JAK11.60848716
26ZAP701.59931871
27MAP3K121.54211261
28TAOK11.53510697
29FGR1.51194267
30BMX1.47950632
31MAP3K131.43366181
32CHUK1.37294305
33LYN1.34587685
34TYRO31.32185969
35SYK1.31542746
36NME21.28987312
37ABL21.28611845
38MST1R1.25868734
39EIF2AK21.23346908
40GRK71.19664646
41HCK1.16595315
42MATK1.09859014
43LCK1.08643057
44ADRBK21.07543291
45IRAK21.06365136
46MAP3K51.03925377
47MAP2K31.03891852
48MUSK1.01193372
49BUB10.97923681
50PIM10.95616976
51CSF1R0.92722097
52BTK0.91770364
53MAP2K60.90486583
54IRAK10.88938317
55FES0.88936594
56PRKCD0.87427582
57STK100.85844189
58MARK30.84383108
59TEC0.81294317
60SCYL20.78961709
61TGFBR20.78106856
62ARAF0.77169161
63YES10.76799646
64SIK30.76353149
65RPS6KA40.75845868
66NEK90.74880718
67ERBB30.74473532
68JAK20.74128851
69TESK20.73334445
70ERBB40.73245717
71STK40.71641404
72TNK20.66220704
73ABL10.60193436
74ITK0.59542228
75EPHB10.58405511
76MAPKAPK30.56130239
77BMPR1B0.51829309
78EGFR0.50681030
79HIPK20.50501894
80EIF2AK30.49994086
81CAMKK20.49431272
82CLK10.48644534
83PRKCQ0.44353794
84DAPK30.44267337
85CDC42BPA0.43475688
86ALK0.42805150
87TRPM70.42494320
88FYN0.42022736
89BCKDK0.39314569
90MOS0.38882463
91TESK10.38596122
92ADRBK10.38144776
93PIK3CG0.37748761
94ACVR1B0.35950968
95WNK40.34955506
96IGF1R0.31284557
97DAPK20.27600150
98INSR0.27588753
99FGFR40.26992799
100PIK3CA0.26685976
101SIK20.25986886
102DYRK30.25641157
103LRRK20.25175051
104MAP3K110.24994606
105PDK10.22533857
106FGFR10.21145186
107MAP3K10.19933824
108TSSK60.18585397
109FGFR30.17941902
110RIPK10.17858473
111MAPK110.17707815
112RPS6KA10.16206611
113PRKCH0.15852766
114DAPK10.15743043
115RPS6KA50.15563119
116STK30.15466255
117MAP3K80.15410942
118SRPK10.14677393
119MAPKAPK20.14498036
120PDPK10.14041124
121PLK20.12551130
122SRC0.11426113
123PKN10.11043205
124EPHA30.08280735
125PRKG20.08248280
126PDGFRB0.07851726
127MYLK0.06217926
128MAPK40.05953562
129NLK0.05796261
130GRK60.05779080
131PRKCE0.05492677
132PRKACG0.04838028
133PRKCA0.04135445

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053325.75610856
2Type I diabetes mellitus_Homo sapiens_hsa049404.06184529
3Allograft rejection_Homo sapiens_hsa053303.46589648
4Leishmaniasis_Homo sapiens_hsa051403.36424225
5Rheumatoid arthritis_Homo sapiens_hsa053233.03809572
6Legionellosis_Homo sapiens_hsa051342.99414589
7* Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.93585100
8Staphylococcus aureus infection_Homo sapiens_hsa051502.91144870
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.73633644
10* Toll-like receptor signaling pathway_Homo sapiens_hsa046202.72590840
11NOD-like receptor signaling pathway_Homo sapiens_hsa046212.55844955
12Pertussis_Homo sapiens_hsa051332.44708101
13Malaria_Homo sapiens_hsa051442.40590209
14RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.36237340
15Asthma_Homo sapiens_hsa053102.32253043
16* NF-kappa B signaling pathway_Homo sapiens_hsa040642.31349032
17African trypanosomiasis_Homo sapiens_hsa051432.14208724
18* Salmonella infection_Homo sapiens_hsa051322.13733725
19Tuberculosis_Homo sapiens_hsa051522.13435557
20Measles_Homo sapiens_hsa051622.01384786
21Osteoclast differentiation_Homo sapiens_hsa043801.94451009
22TNF signaling pathway_Homo sapiens_hsa046681.89150481
23Hematopoietic cell lineage_Homo sapiens_hsa046401.79376212
24Influenza A_Homo sapiens_hsa051641.76397790
25* Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.70990324
26Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.57407825
27Herpes simplex infection_Homo sapiens_hsa051681.52210922
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.41958489
29Intestinal immune network for IgA production_Homo sapiens_hsa046721.40228060
30Prion diseases_Homo sapiens_hsa050201.39969986
31Autoimmune thyroid disease_Homo sapiens_hsa053201.38870492
32Phagosome_Homo sapiens_hsa041451.28534802
33Jak-STAT signaling pathway_Homo sapiens_hsa046301.18500819
34Lysosome_Homo sapiens_hsa041421.18066331
35Antigen processing and presentation_Homo sapiens_hsa046121.14179107
36Toxoplasmosis_Homo sapiens_hsa051451.10093631
37* Chemokine signaling pathway_Homo sapiens_hsa040621.08855874
38Amoebiasis_Homo sapiens_hsa051461.08717094
39Complement and coagulation cascades_Homo sapiens_hsa046100.91158814
40AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.90765138
41Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.90480157
42Apoptosis_Homo sapiens_hsa042100.87835924
43Hepatitis C_Homo sapiens_hsa051600.83923790
44B cell receptor signaling pathway_Homo sapiens_hsa046620.81871987
45Hepatitis B_Homo sapiens_hsa051610.80338546
46T cell receptor signaling pathway_Homo sapiens_hsa046600.74705288
47Viral myocarditis_Homo sapiens_hsa054160.73243555
48Collecting duct acid secretion_Homo sapiens_hsa049660.72109312
49Shigellosis_Homo sapiens_hsa051310.69702596
50Primary immunodeficiency_Homo sapiens_hsa053400.61649933
51Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59843425
52Other glycan degradation_Homo sapiens_hsa005110.58009842
53Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.55831696
54Proteasome_Homo sapiens_hsa030500.51992282
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50585950
56Protein export_Homo sapiens_hsa030600.50459903
57Mineral absorption_Homo sapiens_hsa049780.49280276
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.49132376
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47110328
60Sulfur metabolism_Homo sapiens_hsa009200.46124316
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40901218
62Leukocyte transendothelial migration_Homo sapiens_hsa046700.40584023
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40292275
64Glycosaminoglycan degradation_Homo sapiens_hsa005310.40065835
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38449341
66Adipocytokine signaling pathway_Homo sapiens_hsa049200.37860380
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33755315
68Bladder cancer_Homo sapiens_hsa052190.33462750
69Epstein-Barr virus infection_Homo sapiens_hsa051690.31931605
70Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.28617320
71Type II diabetes mellitus_Homo sapiens_hsa049300.27842340
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26657338
73Platelet activation_Homo sapiens_hsa046110.25490806
74Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.25066927
75HIF-1 signaling pathway_Homo sapiens_hsa040660.22726059
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.19962883
77Vibrio cholerae infection_Homo sapiens_hsa051100.19738787
78Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18660794
79Acute myeloid leukemia_Homo sapiens_hsa052210.17350607
80Oxidative phosphorylation_Homo sapiens_hsa001900.16830300
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.16088517
82Prolactin signaling pathway_Homo sapiens_hsa049170.14567871
83Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.13529149
84Systemic lupus erythematosus_Homo sapiens_hsa053220.12620501
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.10180857
86Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.06946277
87Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.06526284
88Transcriptional misregulation in cancer_Homo sapiens_hsa052020.05943742
89Steroid biosynthesis_Homo sapiens_hsa001000.05930632
90Regulation of autophagy_Homo sapiens_hsa041400.05714896
91Parkinsons disease_Homo sapiens_hsa050120.04735956
92Synaptic vesicle cycle_Homo sapiens_hsa047210.03865508
93HTLV-I infection_Homo sapiens_hsa051660.03569641
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.03401099
95MAPK signaling pathway_Homo sapiens_hsa040100.02160505
96Chronic myeloid leukemia_Homo sapiens_hsa052200.01741813
97Tryptophan metabolism_Homo sapiens_hsa003800.01711968
98Viral carcinogenesis_Homo sapiens_hsa052030.01335140
99Proteoglycans in cancer_Homo sapiens_hsa052050.00306518
100Endocytosis_Homo sapiens_hsa04144-0.0501964
101Ether lipid metabolism_Homo sapiens_hsa00565-0.0456445
102Sphingolipid metabolism_Homo sapiens_hsa00600-0.0430520
103Small cell lung cancer_Homo sapiens_hsa05222-0.0424664
104Caffeine metabolism_Homo sapiens_hsa00232-0.0413491
105Peroxisome_Homo sapiens_hsa04146-0.0388986
106Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080-0.0333001
107Histidine metabolism_Homo sapiens_hsa00340-0.0325261
108Pancreatic cancer_Homo sapiens_hsa05212-0.0276314
109Regulation of actin cytoskeleton_Homo sapiens_hsa04810-0.0191601
110Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0190594
111Alzheimers disease_Homo sapiens_hsa05010-0.0168513
112Insulin resistance_Homo sapiens_hsa04931-0.0166620
113VEGF signaling pathway_Homo sapiens_hsa04370-0.0111672
114alpha-Linolenic acid metabolism_Homo sapiens_hsa00592-0.0109189
115Fatty acid biosynthesis_Homo sapiens_hsa00061-0.0106226
116RNA polymerase_Homo sapiens_hsa03020-0.0055406

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