Rank | Gene Set | Z-score |
---|---|---|
1 | cytidine metabolic process (GO:0046087) | 8.55826403 |
2 | cytidine catabolic process (GO:0006216) | 8.55826403 |
3 | cytidine deamination (GO:0009972) | 8.55826403 |
4 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.62206577 |
5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.84245300 |
6 | DNA deamination (GO:0045006) | 6.25197920 |
7 | regulation of T-helper 1 cell differentiation (GO:0045625) | 5.63847881 |
8 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 5.50068096 |
9 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.30395070 |
10 | regulation of regulatory T cell differentiation (GO:0045589) | 5.13596772 |
11 | positive regulation of type 2 immune response (GO:0002830) | 5.09523467 |
12 | regulation of natural killer cell mediated immunity (GO:0002715) | 5.09236819 |
13 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 5.09236819 |
14 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.07809727 |
15 | T-helper 1 type immune response (GO:0042088) | 5.06313121 |
16 | cellular response to interleukin-15 (GO:0071350) | 5.06110888 |
17 | cellular response to type I interferon (GO:0071357) | 4.95102188 |
18 | type I interferon signaling pathway (GO:0060337) | 4.95102188 |
19 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.94650528 |
20 | positive regulation of T-helper cell differentiation (GO:0045624) | 4.91187631 |
21 | positive regulation of natural killer cell differentiation (GO:0032825) | 4.90759950 |
22 | neutrophil activation involved in immune response (GO:0002283) | 4.89856290 |
23 | positive regulation of T cell cytokine production (GO:0002726) | 4.88786699 |
24 | response to type I interferon (GO:0034340) | 4.87942391 |
25 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 4.75244086 |
26 | regulation of T-helper 2 cell differentiation (GO:0045628) | 4.74952442 |
27 | regulation of memory T cell differentiation (GO:0043380) | 4.72215375 |
28 | negative thymic T cell selection (GO:0045060) | 4.71186668 |
29 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.68218061 |
30 | negative T cell selection (GO:0043383) | 4.62660113 |
31 | T cell migration (GO:0072678) | 4.51661418 |
32 | positive regulation of interleukin-12 production (GO:0032735) | 4.49563085 |
33 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.44692198 |
34 | negative regulation of cell killing (GO:0031342) | 4.44604248 |
35 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.44604248 |
36 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 4.40422254 |
37 | response to interleukin-15 (GO:0070672) | 4.39479644 |
38 | positive regulation of interferon-alpha production (GO:0032727) | 4.36566346 |
39 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.34520100 |
40 | regulation of T cell tolerance induction (GO:0002664) | 4.33581542 |
41 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 4.28648675 |
42 | myeloid dendritic cell differentiation (GO:0043011) | 4.26229424 |
43 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.23972041 |
44 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 4.23836833 |
45 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.22162334 |
46 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.21695726 |
47 | cellular response to zinc ion (GO:0071294) | 4.17159042 |
48 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.16797373 |
49 | positive regulation of isotype switching (GO:0045830) | 4.15873275 |
50 | positive regulation of defense response to virus by host (GO:0002230) | 4.13475702 |
51 | regulation of T-helper cell differentiation (GO:0045622) | 4.12044329 |
52 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.10094508 |
53 | regulation of interferon-alpha production (GO:0032647) | 4.09191321 |
54 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.07168297 |
55 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 4.06902050 |
56 | regulation of hypersensitivity (GO:0002883) | 4.06610590 |
57 | positive regulation of tolerance induction (GO:0002645) | 4.02959492 |
58 | regulation of RIG-I signaling pathway (GO:0039535) | 4.01057557 |
59 | natural killer cell mediated immunity (GO:0002228) | 3.99171394 |
60 | natural killer cell mediated cytotoxicity (GO:0042267) | 3.99171394 |
61 | positive regulation of interleukin-17 production (GO:0032740) | 3.98197194 |
62 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.98043195 |
63 | cellular response to interferon-beta (GO:0035458) | 3.97894293 |
64 | positive regulation of humoral immune response (GO:0002922) | 3.97757689 |
65 | natural killer cell activation (GO:0030101) | 3.96308081 |
66 | regulation of immunoglobulin secretion (GO:0051023) | 3.95923467 |
67 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.94910495 |
68 | myeloid dendritic cell activation (GO:0001773) | 3.94081841 |
69 | positive regulation of cell killing (GO:0031343) | 3.93559084 |
70 | regulation of cell killing (GO:0031341) | 3.92424127 |
71 | negative regulation of interleukin-17 production (GO:0032700) | 3.88688967 |
72 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.88578217 |
73 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.88578217 |
74 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.84236580 |
75 | positive regulation of interleukin-2 production (GO:0032743) | 3.83503795 |
76 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.82844677 |
77 | positive regulation of antigen processing and presentation (GO:0002579) | 3.81867393 |
78 | positive T cell selection (GO:0043368) | 3.80991061 |
79 | positive thymic T cell selection (GO:0045059) | 3.80805412 |
80 | cellular response to interferon-alpha (GO:0035457) | 3.79356890 |
81 | positive regulation of DNA recombination (GO:0045911) | 3.78349360 |
82 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.76404383 |
83 | regulation of gamma-delta T cell activation (GO:0046643) | 3.71320927 |
84 | T cell costimulation (GO:0031295) | 3.71166641 |
85 | * regulation of activation of Janus kinase activity (GO:0010533) | 3.71044483 |
86 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.68849298 |
87 | regulation of T-helper 1 type immune response (GO:0002825) | 3.66949324 |
88 | actin nucleation (GO:0045010) | 3.66684824 |
89 | lymphocyte costimulation (GO:0031294) | 3.66088345 |
90 | response to interferon-alpha (GO:0035455) | 3.64609942 |
91 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.63323662 |
92 | natural killer cell differentiation (GO:0001779) | 3.61733044 |
93 | * negative regulation of viral genome replication (GO:0045071) | 3.60550493 |
94 | positive regulation of B cell differentiation (GO:0045579) | 3.59150107 |
95 | defense response to protozoan (GO:0042832) | 3.56714885 |
96 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.54933941 |
97 | regulation of T cell cytokine production (GO:0002724) | 3.54629742 |
98 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.53706192 |
99 | positive regulation of B cell mediated immunity (GO:0002714) | 3.53706192 |
100 | lymphocyte migration (GO:0072676) | 3.53680801 |
101 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.53367723 |
102 | positive regulation of interleukin-10 production (GO:0032733) | 3.52692694 |
103 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.52292808 |
104 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.51923032 |
105 | cellular defense response (GO:0006968) | 3.51181460 |
106 | response to peptidoglycan (GO:0032494) | 3.49901462 |
107 | positive regulation of activated T cell proliferation (GO:0042104) | 3.49869523 |
108 | regulation of interleukin-12 production (GO:0032655) | 3.49774601 |
109 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.49503047 |
110 | regulation of tolerance induction (GO:0002643) | 3.49459184 |
111 | cellular response to exogenous dsRNA (GO:0071360) | 3.48593058 |
112 | interferon-gamma production (GO:0032609) | 3.48174341 |
113 | * granulocyte activation (GO:0036230) | 3.47549638 |
114 | lymphocyte chemotaxis (GO:0048247) | 3.45504773 |
115 | regulation of interleukin-17 production (GO:0032660) | 3.45070546 |
116 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.41026097 |
117 | negative regulation of B cell proliferation (GO:0030889) | 3.39704323 |
118 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.38266405 |
119 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.37048674 |
120 | regulation of response to tumor cell (GO:0002834) | 3.36703876 |
121 | positive regulation of response to tumor cell (GO:0002836) | 3.36703876 |
122 | positive regulation of immune response to tumor cell (GO:0002839) | 3.36703876 |
123 | regulation of immune response to tumor cell (GO:0002837) | 3.36703876 |
124 | regulation of B cell differentiation (GO:0045577) | 3.35110238 |
125 | cytolysis (GO:0019835) | 3.34333235 |
126 | immunoglobulin mediated immune response (GO:0016064) | 3.33647342 |
127 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.33518234 |
128 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.33518234 |
129 | * neutrophil activation (GO:0042119) | 3.33397372 |
130 | positive regulation of interferon-gamma production (GO:0032729) | 3.32926231 |
131 | positive regulation of alpha-beta T cell differentiation (GO:0046638) | 3.31653976 |
132 | positive regulation of response to biotic stimulus (GO:0002833) | 3.30700396 |
133 | T-helper cell differentiation (GO:0042093) | 3.30676948 |
134 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.30676948 |
135 | regulation of antigen processing and presentation (GO:0002577) | 3.30503796 |
136 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.30304649 |
137 | response to interferon-beta (GO:0035456) | 3.29505495 |
138 | activated T cell proliferation (GO:0050798) | 3.28905480 |
139 | NIK/NF-kappaB signaling (GO:0038061) | 3.27651630 |
140 | T cell receptor signaling pathway (GO:0050852) | 3.26938451 |
141 | thymic T cell selection (GO:0045061) | 3.24103759 |
142 | dendritic cell differentiation (GO:0097028) | 3.22695520 |
143 | cellular response to virus (GO:0098586) | 3.22486737 |
144 | regulation of calcium-mediated signaling (GO:0050848) | 3.17005899 |
145 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.15882763 |
146 | T cell selection (GO:0045058) | 3.15512199 |
147 | negative regulation of interleukin-12 production (GO:0032695) | 3.13402297 |
148 | regulation of interleukin-8 secretion (GO:2000482) | 3.04107063 |
149 | * negative regulation of viral process (GO:0048525) | 3.02868519 |
150 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.02329331 |
151 | B cell mediated immunity (GO:0019724) | 3.01697273 |
152 | * negative regulation of T cell apoptotic process (GO:0070233) | 3.00829976 |
153 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.00577120 |
154 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.95490138 |
155 | regulation of defense response to virus by host (GO:0050691) | 2.95475365 |
156 | * regulation of viral genome replication (GO:0045069) | 2.95354439 |
157 | positive regulation of macrophage differentiation (GO:0045651) | 2.90779576 |
158 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.88870539 |
159 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 2.88766303 |
160 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.87328016 |
161 | negative regulation of T cell activation (GO:0050868) | 2.87104405 |
162 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.84381687 |
163 | negative regulation of B cell activation (GO:0050869) | 2.84333757 |
164 | positive regulation of leukocyte mediated immunity (GO:0002705) | 2.79405924 |
165 | regulation of lymphocyte mediated immunity (GO:0002706) | 2.78712095 |
166 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.78304549 |
167 | leukocyte degranulation (GO:0043299) | 2.77729835 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 8.43641499 |
2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.93530542 |
3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 6.37685516 |
4 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 5.72764102 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.63904720 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.63434258 |
7 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.92501159 |
8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.92482546 |
9 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.50352114 |
10 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.39838348 |
11 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.32897909 |
12 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.12373787 |
13 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.00298670 |
14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.93018423 |
15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.87384006 |
16 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.54102027 |
17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.10642235 |
18 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.06748991 |
19 | * MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.06613134 |
20 | MYB_26560356_Chip-Seq_TH2_Human | 2.04272064 |
21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.03089060 |
22 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.98056422 |
23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.90871314 |
24 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.79567128 |
25 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.76596729 |
26 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.75608320 |
27 | MAF_26560356_Chip-Seq_TH1_Human | 1.70326662 |
28 | MYB_26560356_Chip-Seq_TH1_Human | 1.66154407 |
29 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.55312768 |
30 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.52523367 |
31 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.52112684 |
32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.47192276 |
33 | * NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.47175166 |
34 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.46384116 |
35 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.46243530 |
36 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.42945708 |
37 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.39401694 |
38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.38204570 |
39 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.37632431 |
40 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.37569684 |
41 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.35448711 |
42 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.30870702 |
43 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.29129394 |
44 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.26879759 |
45 | GATA1_22025678_ChIP-Seq_K562_Human | 1.25469935 |
46 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.25439406 |
47 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.24470156 |
48 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.22077946 |
49 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.22061861 |
50 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.21484508 |
51 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.15793654 |
52 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.15712323 |
53 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.13131986 |
54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12764494 |
55 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10927769 |
56 | SPI1_23127762_ChIP-Seq_K562_Human | 1.09543903 |
57 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08114812 |
58 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07297951 |
59 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06726598 |
60 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.04563770 |
61 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.03900500 |
62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.99449400 |
63 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.99193982 |
64 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98375481 |
65 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.98274968 |
66 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.97777753 |
67 | * LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96171539 |
68 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.95890197 |
69 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95071942 |
70 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90822984 |
71 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.90422462 |
72 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.89871523 |
73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.89609430 |
74 | GATA3_26560356_Chip-Seq_TH1_Human | 0.89526428 |
75 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.88519452 |
76 | GATA1_19941826_ChIP-Seq_K562_Human | 0.87845593 |
77 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87799300 |
78 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87302031 |
79 | * NANOG_20526341_ChIP-Seq_ESCs_Human | 0.86922130 |
80 | SA1_27219007_Chip-Seq_Bcells_Human | 0.86049866 |
81 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.85226287 |
82 | MAF_26560356_Chip-Seq_TH2_Human | 0.85213813 |
83 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.84393855 |
84 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.83403176 |
85 | * BCOR_27268052_Chip-Seq_Bcells_Human | 0.83389754 |
86 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.82581801 |
87 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.82408914 |
88 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.81417922 |
89 | UTX_26944678_Chip-Seq_JUKART_Human | 0.80914547 |
90 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.80890141 |
91 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.80317667 |
92 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.79450295 |
93 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.78968380 |
94 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.77770954 |
95 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.76992122 |
96 | * P300_27268052_Chip-Seq_Bcells_Human | 0.76107062 |
97 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.75687627 |
98 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.75656375 |
99 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74981156 |
100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74225171 |
101 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.73704244 |
102 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.73266274 |
103 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.73027221 |
104 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.72696819 |
105 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.72614935 |
106 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.72348882 |
107 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.72348882 |
108 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.71877571 |
109 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.71284358 |
110 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.69647426 |
111 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.69623351 |
112 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.69028841 |
113 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.68652527 |
114 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.67785682 |
115 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.67548445 |
116 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.67175509 |
117 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.66398334 |
118 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.66343808 |
119 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.64802835 |
120 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.64326857 |
121 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.63877845 |
122 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.62215526 |
123 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.61245111 |
124 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.60271181 |
125 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.59988468 |
126 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.59040327 |
127 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.58386878 |
128 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.56418212 |
129 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.56294399 |
130 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.56294399 |
131 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.56181502 |
132 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.55243793 |
133 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.54759552 |
134 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.52654046 |
135 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.52594489 |
136 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.52395042 |
137 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.50775408 |
138 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.50399139 |
139 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.50292214 |
140 | CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.49817516 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 5.37120085 |
2 | MP0009785_altered_susceptibility_to | 4.65817955 |
3 | MP0005671_abnormal_response_to | 4.57304637 |
4 | * MP0002148_abnormal_hypersensitivity_rea | 4.22366988 |
5 | MP0000685_abnormal_immune_system | 4.20829811 |
6 | MP0006082_CNS_inflammation | 3.80131366 |
7 | MP0003436_decreased_susceptibility_to | 3.54251520 |
8 | MP0001790_abnormal_immune_system | 3.53663766 |
9 | MP0005387_immune_system_phenotype | 3.53663766 |
10 | MP0005000_abnormal_immune_tolerance | 3.46509585 |
11 | MP0005025_abnormal_response_to | 3.23753365 |
12 | MP0003724_increased_susceptibility_to | 2.89662168 |
13 | MP0001800_abnormal_humoral_immune | 2.82473831 |
14 | * MP0002723_abnormal_immune_serum | 2.77686769 |
15 | MP0002419_abnormal_innate_immunity | 2.70022665 |
16 | MP0002452_abnormal_antigen_presenting | 2.70005061 |
17 | MP0002006_tumorigenesis | 2.62785458 |
18 | MP0001348_abnormal_lacrimal_gland | 2.61047758 |
19 | MP0004510_myositis | 2.59672931 |
20 | MP0002163_abnormal_gland_morphology | 2.57984869 |
21 | * MP0001819_abnormal_immune_cell | 2.50632346 |
22 | * MP0002420_abnormal_adaptive_immunity | 2.44321938 |
23 | MP0005310_abnormal_salivary_gland | 2.18286495 |
24 | MP0002166_altered_tumor_susceptibility | 2.17791733 |
25 | MP0003763_abnormal_thymus_physiology | 1.95173140 |
26 | MP0002138_abnormal_hepatobiliary_system | 1.91034324 |
27 | MP0002405_respiratory_system_inflammati | 1.89677080 |
28 | MP0001346_abnormal_lacrimal_gland | 1.87751540 |
29 | MP0009764_decreased_sensitivity_to | 1.87671270 |
30 | * MP0000716_abnormal_immune_system | 1.87154095 |
31 | MP0001845_abnormal_inflammatory_respons | 1.83338770 |
32 | * MP0002398_abnormal_bone_marrow | 1.83245317 |
33 | MP0004947_skin_inflammation | 1.78787538 |
34 | MP0001853_heart_inflammation | 1.78382667 |
35 | MP0001533_abnormal_skeleton_physiology | 1.76522424 |
36 | MP0003448_altered_tumor_morphology | 1.75796250 |
37 | MP0010155_abnormal_intestine_physiology | 1.65120550 |
38 | MP0008469_abnormal_protein_level | 1.61483506 |
39 | MP0000858_altered_metastatic_potential | 1.54611259 |
40 | MP0003300_gastrointestinal_ulcer | 1.51496253 |
41 | MP0005464_abnormal_platelet_physiology | 1.50792020 |
42 | MP0003303_peritoneal_inflammation | 1.47531427 |
43 | MP0009333_abnormal_splenocyte_physiolog | 1.46600305 |
44 | * MP0002429_abnormal_blood_cell | 1.41403375 |
45 | MP0008004_abnormal_stomach_pH | 1.40438138 |
46 | MP0000569_abnormal_digit_pigmentation | 1.38660708 |
47 | MP0002722_abnormal_immune_system | 1.31075001 |
48 | MP0005379_endocrine/exocrine_gland_phen | 1.29283633 |
49 | MP0002277_abnormal_respiratory_mucosa | 1.27856986 |
50 | MP0000689_abnormal_spleen_morphology | 1.25585715 |
51 | MP0002009_preneoplasia | 1.16841780 |
52 | MP0002998_abnormal_bone_remodeling | 1.16269862 |
53 | MP0004782_abnormal_surfactant_physiolog | 1.06830628 |
54 | MP0001919_abnormal_reproductive_system | 1.05551545 |
55 | MP0005058_abnormal_lysosome_morphology | 1.05466723 |
56 | MP0009763_increased_sensitivity_to | 0.97903561 |
57 | MP0003806_abnormal_nucleotide_metabolis | 0.97845761 |
58 | MP0003186_abnormal_redox_activity | 0.95522334 |
59 | MP0000703_abnormal_thymus_morphology | 0.92958805 |
60 | MP0003195_calcinosis | 0.92162133 |
61 | MP0002254_reproductive_system_inflammat | 0.91905459 |
62 | MP0005397_hematopoietic_system_phenotyp | 0.89185412 |
63 | MP0001545_abnormal_hematopoietic_system | 0.89185412 |
64 | MP0005166_decreased_susceptibility_to | 0.88314358 |
65 | MP0003075_altered_response_to | 0.87140721 |
66 | MP0002933_joint_inflammation | 0.84656535 |
67 | MP0003183_abnormal_peptide_metabolism | 0.84070157 |
68 | MP0001501_abnormal_sleep_pattern | 0.83583362 |
69 | MP0000465_gastrointestinal_hemorrhage | 0.82550708 |
70 | MP0000343_altered_response_to | 0.81632944 |
71 | MP0003091_abnormal_cell_migration | 0.80610231 |
72 | MP0003191_abnormal_cellular_cholesterol | 0.78459941 |
73 | MP0001663_abnormal_digestive_system | 0.77517238 |
74 | MP0001873_stomach_inflammation | 0.76326087 |
75 | MP0005390_skeleton_phenotype | 0.74394895 |
76 | MP0003045_fibrosis | 0.73577084 |
77 | MP0001542_abnormal_bone_strength | 0.71896822 |
78 | MP0010386_abnormal_urinary_bladder | 0.70281550 |
79 | MP0008057_abnormal_DNA_replication | 0.69665080 |
80 | MP0005451_abnormal_body_composition | 0.66918341 |
81 | MP0005076_abnormal_cell_differentiation | 0.66663824 |
82 | MP0008873_increased_physiological_sensi | 0.66263290 |
83 | MP0000604_amyloidosis | 0.65664571 |
84 | MP0004130_abnormal_muscle_cell | 0.65495093 |
85 | MP0005410_abnormal_fertilization | 0.65203443 |
86 | MP0002876_abnormal_thyroid_physiology | 0.65139158 |
87 | MP0001881_abnormal_mammary_gland | 0.64827784 |
88 | MP0002136_abnormal_kidney_physiology | 0.64713791 |
89 | MP0003866_abnormal_defecation | 0.64186579 |
90 | MP0009278_abnormal_bone_marrow | 0.63315356 |
91 | MP0009840_abnormal_foam_cell | 0.62840991 |
92 | MP0003172_abnormal_lysosome_physiology | 0.62837791 |
93 | MP0003453_abnormal_keratinocyte_physiol | 0.62695402 |
94 | MP0002132_abnormal_respiratory_system | 0.62551268 |
95 | MP0005165_increased_susceptibility_to | 0.61639014 |
96 | MP0005164_abnormal_response_to | 0.61137266 |
97 | MP0008874_decreased_physiological_sensi | 0.60243506 |
98 | MP0009643_abnormal_urine_homeostasis | 0.59402560 |
99 | MP0002332_abnormal_exercise_endurance | 0.58897704 |
100 | MP0004381_abnormal_hair_follicle | 0.58882878 |
101 | MP0000371_diluted_coat_color | 0.58560536 |
102 | MP0004883_abnormal_blood_vessel | 0.58201036 |
103 | MP0002019_abnormal_tumor_incidence | 0.57582731 |
104 | MP0002693_abnormal_pancreas_physiology | 0.57512022 |
105 | MP0000249_abnormal_blood_vessel | 0.57387385 |
106 | MP0005174_abnormal_tail_pigmentation | 0.56698079 |
107 | MP0003646_muscle_fatigue | 0.56185010 |
108 | MP0000627_abnormal_mammary_gland | 0.54470238 |
109 | MP0003566_abnormal_cell_adhesion | 0.54019358 |
110 | MP0001905_abnormal_dopamine_level | 0.51657005 |
111 | MP0001765_abnormal_ion_homeostasis | 0.50143250 |
112 | MP0000372_irregular_coat_pigmentation | 0.49730437 |
113 | MP0000613_abnormal_salivary_gland | 0.49683058 |
114 | MP0010307_abnormal_tumor_latency | 0.48890381 |
115 | MP0009765_abnormal_xenobiotic_induced | 0.48481923 |
116 | MP0005389_reproductive_system_phenotype | 0.47938514 |
117 | MP0002139_abnormal_hepatobiliary_system | 0.46567524 |
118 | MP0000230_abnormal_systemic_arterial | 0.46512703 |
119 | MP0001191_abnormal_skin_condition | 0.45749557 |
120 | MP0000920_abnormal_myelination | 0.45371944 |
121 | MP0004808_abnormal_hematopoietic_stem | 0.45369380 |
122 | MP0005167_abnormal_blood-brain_barrier | 0.43508718 |
123 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.41287769 |
124 | MP0003690_abnormal_glial_cell | 0.39953326 |
125 | MP0002877_abnormal_melanocyte_morpholog | 0.39759023 |
126 | MP0000490_abnormal_crypts_of | 0.38881086 |
127 | MP0001851_eye_inflammation | 0.38627042 |
128 | MP0005535_abnormal_body_temperature | 0.35685659 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased IgM level (HP:0003496) | 7.29361406 |
2 | Autoimmune thrombocytopenia (HP:0001973) | 6.04893294 |
3 | Eczematoid dermatitis (HP:0000976) | 6.01898365 |
4 | Recurrent abscess formation (HP:0002722) | 5.79257320 |
5 | Recurrent bacterial skin infections (HP:0005406) | 5.58567319 |
6 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.42250647 |
7 | Retrobulbar optic neuritis (HP:0100654) | 5.36378334 |
8 | Optic neuritis (HP:0100653) | 5.36378334 |
9 | Orchitis (HP:0100796) | 5.00361659 |
10 | Abnormality of T cell number (HP:0011839) | 4.95119646 |
11 | Gastrointestinal infarctions (HP:0005244) | 4.84501116 |
12 | Myositis (HP:0100614) | 4.80323290 |
13 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.70044458 |
14 | Vasculitis (HP:0002633) | 4.64340896 |
15 | Mediastinal lymphadenopathy (HP:0100721) | 4.57681287 |
16 | Abnormality of macrophages (HP:0004311) | 4.32276298 |
17 | T lymphocytopenia (HP:0005403) | 4.18162355 |
18 | Hypergammaglobulinemia (HP:0010702) | 4.13650381 |
19 | Hypoproteinemia (HP:0003075) | 4.06162610 |
20 | Recurrent fungal infections (HP:0002841) | 4.03603051 |
21 | Basal ganglia calcification (HP:0002135) | 3.97424444 |
22 | Aplastic anemia (HP:0001915) | 3.90017737 |
23 | Recurrent viral infections (HP:0004429) | 3.80981883 |
24 | Autoimmune hemolytic anemia (HP:0001890) | 3.79318798 |
25 | Stomatitis (HP:0010280) | 3.68320357 |
26 | Chronic otitis media (HP:0000389) | 3.66151934 |
27 | Recurrent skin infections (HP:0001581) | 3.65747499 |
28 | Nasal polyposis (HP:0100582) | 3.38192953 |
29 | Pulmonary infiltrates (HP:0002113) | 3.35915940 |
30 | Abnormality of T cells (HP:0002843) | 3.34554396 |
31 | Gingivitis (HP:0000230) | 3.33277898 |
32 | Systemic lupus erythematosus (HP:0002725) | 3.26562614 |
33 | Joint swelling (HP:0001386) | 3.21914673 |
34 | Keratoconjunctivitis sicca (HP:0001097) | 3.20555659 |
35 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.16782053 |
36 | Hemoptysis (HP:0002105) | 3.14361919 |
37 | Chronic obstructive pulmonary disease (HP:0006510) | 3.13058351 |
38 | Obstructive lung disease (HP:0006536) | 3.13058351 |
39 | Recurrent cutaneous fungal infections (HP:0011370) | 3.05350971 |
40 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.05350971 |
41 | Pustule (HP:0200039) | 3.04398967 |
42 | Porencephaly (HP:0002132) | 3.04156170 |
43 | Arterial thrombosis (HP:0004420) | 3.02084622 |
44 | Periodontitis (HP:0000704) | 2.99771310 |
45 | Hemiplegia (HP:0002301) | 2.97530952 |
46 | Tetraparesis (HP:0002273) | 2.96320443 |
47 | Keratoconjunctivitis (HP:0001096) | 2.93757435 |
48 | Meningitis (HP:0001287) | 2.91853892 |
49 | Abnormality of the prostate (HP:0008775) | 2.87662592 |
50 | Eosinophilia (HP:0001880) | 2.85781626 |
51 | Leukocytosis (HP:0001974) | 2.85658450 |
52 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.84736659 |
53 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.84736659 |
54 | Abnormality of glycolipid metabolism (HP:0010969) | 2.84736659 |
55 | IgG deficiency (HP:0004315) | 2.82191766 |
56 | Gangrene (HP:0100758) | 2.80698951 |
57 | Interstitial pulmonary disease (HP:0006530) | 2.80102943 |
58 | Anorexia (HP:0002039) | 2.79168064 |
59 | Abnormality of the nasal mucosa (HP:0000433) | 2.79050430 |
60 | Increased serum ferritin (HP:0003281) | 2.74373317 |
61 | Recurrent bronchitis (HP:0002837) | 2.71077890 |
62 | Encephalitis (HP:0002383) | 2.66056987 |
63 | Prolonged bleeding time (HP:0003010) | 2.65974027 |
64 | Abnormality of eosinophils (HP:0001879) | 2.65649867 |
65 | Abnormality of T cell physiology (HP:0011840) | 2.63693643 |
66 | Epistaxis (HP:0000421) | 2.62457252 |
67 | Combined immunodeficiency (HP:0005387) | 2.56760891 |
68 | IgA deficiency (HP:0002720) | 2.53976275 |
69 | Abnormality of the pericardium (HP:0001697) | 2.53762204 |
70 | Prolonged neonatal jaundice (HP:0006579) | 2.53044829 |
71 | Purpura (HP:0000979) | 2.51910850 |
72 | Abnormality of B cell number (HP:0010975) | 2.50531762 |
73 | Urticaria (HP:0001025) | 2.47265171 |
74 | Cleft eyelid (HP:0000625) | 2.44588951 |
75 | Thick nail (HP:0001805) | 2.42203022 |
76 | Gingival bleeding (HP:0000225) | 2.38352648 |
77 | Recurrent pneumonia (HP:0006532) | 2.37837035 |
78 | Severe combined immunodeficiency (HP:0004430) | 2.36781349 |
79 | Abnormality of iron homeostasis (HP:0011031) | 2.36203173 |
80 | Poor head control (HP:0002421) | 2.33325107 |
81 | Petechiae (HP:0000967) | 2.33058451 |
82 | Granulocytopenia (HP:0001913) | 2.31958061 |
83 | Cellulitis (HP:0100658) | 2.31071412 |
84 | Amaurosis fugax (HP:0100576) | 2.29116839 |
85 | Keratitis (HP:0000491) | 2.26735907 |
86 | Abnormality of the pleura (HP:0002103) | 2.25453903 |
87 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.24975052 |
88 | Chest pain (HP:0100749) | 2.24024530 |
89 | Recurrent lower respiratory tract infections (HP:0002783) | 2.23782804 |
90 | Chronic sinusitis (HP:0011109) | 2.22153569 |
91 | Arthralgia (HP:0002829) | 2.22144067 |
92 | Abnormal albumin level (HP:0012116) | 2.21849378 |
93 | Hypoalbuminemia (HP:0003073) | 2.21849378 |
94 | Agammaglobulinemia (HP:0004432) | 2.21527427 |
95 | Prostate neoplasm (HP:0100787) | 2.21430408 |
96 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.21241728 |
97 | Polyneuropathy (HP:0001271) | 2.20148161 |
98 | 3-Methylglutaconic aciduria (HP:0003535) | 2.18546604 |
99 | Increased cerebral lipofuscin (HP:0011813) | 2.17910779 |
100 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.17896237 |
101 | Lymphoma (HP:0002665) | 2.17678692 |
102 | Vacuolated lymphocytes (HP:0001922) | 2.17551857 |
103 | Thyroiditis (HP:0100646) | 2.16537338 |
104 | Lower limb hyperreflexia (HP:0002395) | 2.16178708 |
105 | Hypochromic anemia (HP:0001931) | 2.11068613 |
106 | Cerebral ischemia (HP:0002637) | 2.10712201 |
107 | Hypoplasia of the thymus (HP:0000778) | 2.06084010 |
108 | Chronic diarrhea (HP:0002028) | 2.05425337 |
109 | Premature loss of primary teeth (HP:0006323) | 2.04433093 |
110 | Episodic fever (HP:0001954) | 2.02993804 |
111 | Hepatosplenomegaly (HP:0001433) | 2.02910424 |
112 | Ureteral stenosis (HP:0000071) | 2.02791901 |
113 | Osteolytic defects of the hand bones (HP:0009699) | 2.02154642 |
114 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.02154642 |
115 | Abnormality of the endocardium (HP:0004306) | 2.01669267 |
116 | Tetraplegia (HP:0002445) | 2.01150786 |
117 | Glomerulopathy (HP:0100820) | 1.99054023 |
118 | Vertebral compression fractures (HP:0002953) | 1.98380054 |
119 | Acute hepatic failure (HP:0006554) | 1.97606528 |
120 | Lymphopenia (HP:0001888) | 1.96601416 |
121 | Hemorrhage of the eye (HP:0011885) | 1.96390957 |
122 | Neutropenia (HP:0001875) | 1.95733429 |
123 | IgM deficiency (HP:0002850) | 1.94793720 |
124 | Skin ulcer (HP:0200042) | 1.91745822 |
125 | B lymphocytopenia (HP:0010976) | 1.90572088 |
126 | Ureteral obstruction (HP:0006000) | 1.88370287 |
127 | Pulmonary fibrosis (HP:0002206) | 1.87743202 |
128 | Dysostosis multiplex (HP:0000943) | 1.86683319 |
129 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.86392324 |
130 | Pulmonary embolism (HP:0002204) | 1.86034062 |
131 | J-shaped sella turcica (HP:0002680) | 1.85459932 |
132 | Spontaneous hematomas (HP:0007420) | 1.85417850 |
133 | Skin rash (HP:0000988) | 1.84854861 |
134 | Bronchitis (HP:0012387) | 1.84461243 |
135 | Osteomyelitis (HP:0002754) | 1.84000133 |
136 | Increased IgE level (HP:0003212) | 1.83852765 |
137 | Thrombocytosis (HP:0001894) | 1.83194173 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K14 | 5.42914460 |
2 | KDR | 3.93378183 |
3 | JAK3 | 3.92515828 |
4 | TBK1 | 3.81064865 |
5 | PBK | 3.72005875 |
6 | TYK2 | 3.58732273 |
7 | IKBKE | 3.15859073 |
8 | TESK2 | 3.11265506 |
9 | IKBKB | 3.09000515 |
10 | IRAK4 | 2.99543574 |
11 | TXK | 2.94069223 |
12 | RIPK4 | 2.92085558 |
13 | JAK1 | 2.65458174 |
14 | MAP3K13 | 2.60371582 |
15 | BLK | 2.50559180 |
16 | MST4 | 2.21805781 |
17 | CHUK | 2.15882994 |
18 | MAP4K1 | 2.09478726 |
19 | PIM2 | 2.08887338 |
20 | BMPR2 | 2.02182609 |
21 | CSK | 1.80596373 |
22 | NEK9 | 1.78412714 |
23 | SYK | 1.59608905 |
24 | TYRO3 | 1.50903139 |
25 | BCKDK | 1.49006318 |
26 | TLK1 | 1.47332914 |
27 | ZAP70 | 1.46755195 |
28 | BCR | 1.45267365 |
29 | IRAK3 | 1.44891989 |
30 | ARAF | 1.40201462 |
31 | SIK3 | 1.36843494 |
32 | FGFR4 | 1.36508831 |
33 | DAPK2 | 1.35961267 |
34 | PIM1 | 1.32466735 |
35 | STK4 | 1.27295482 |
36 | EPHB1 | 1.22234346 |
37 | KIT | 1.18156771 |
38 | EIF2AK2 | 1.18015776 |
39 | NUAK1 | 1.17576784 |
40 | MAPKAPK3 | 1.15925367 |
41 | LCK | 1.15715634 |
42 | MAP3K12 | 1.09506089 |
43 | PRKCQ | 1.04459724 |
44 | FGFR3 | 1.04305639 |
45 | HCK | 1.02372538 |
46 | ITK | 1.02192894 |
47 | BMX | 1.00358250 |
48 | ABL2 | 0.99952235 |
49 | TESK1 | 0.99658714 |
50 | BTK | 0.96222128 |
51 | JAK2 | 0.95365937 |
52 | TNK2 | 0.94280057 |
53 | CAMKK2 | 0.94109145 |
54 | RPS6KA4 | 0.90408302 |
55 | LYN | 0.87599471 |
56 | MARK3 | 0.87123705 |
57 | IRAK1 | 0.85056672 |
58 | CLK1 | 0.79908348 |
59 | NME2 | 0.78892809 |
60 | TAOK2 | 0.76744195 |
61 | EPHA3 | 0.75624532 |
62 | WNK4 | 0.75543372 |
63 | ZAK | 0.74699206 |
64 | SIK2 | 0.72348043 |
65 | PIK3CA | 0.71326587 |
66 | YES1 | 0.70101889 |
67 | ADRBK2 | 0.69420326 |
68 | PRKCD | 0.66513450 |
69 | IRAK2 | 0.65679448 |
70 | ERBB3 | 0.65578691 |
71 | GRK5 | 0.65467707 |
72 | LIMK1 | 0.65041396 |
73 | TEC | 0.64751006 |
74 | TGFBR2 | 0.61232921 |
75 | GRK1 | 0.60853133 |
76 | MYLK | 0.60435950 |
77 | NLK | 0.60154848 |
78 | TRPM7 | 0.59163148 |
79 | PIK3CG | 0.57667490 |
80 | TAOK3 | 0.57558632 |
81 | MAP3K5 | 0.54255740 |
82 | ABL1 | 0.54212841 |
83 | PDK1 | 0.54182552 |
84 | PDGFRB | 0.53641130 |
85 | ACVR1B | 0.53619141 |
86 | MST1R | 0.52834407 |
87 | STK24 | 0.51599280 |
88 | STK10 | 0.49592952 |
89 | GRK7 | 0.46889193 |
90 | STK3 | 0.46787975 |
91 | CSF1R | 0.46755738 |
92 | PKN1 | 0.45408926 |
93 | FRK | 0.44849655 |
94 | FES | 0.44562114 |
95 | RAF1 | 0.44450686 |
96 | DAPK1 | 0.42584799 |
97 | MAPKAPK2 | 0.41585460 |
98 | MOS | 0.38004114 |
99 | PRKCH | 0.34970809 |
100 | ADRBK1 | 0.34642482 |
101 | PAK1 | 0.34502659 |
102 | GRK6 | 0.33601036 |
103 | MAP3K3 | 0.33417065 |
104 | ERN1 | 0.33239095 |
105 | DAPK3 | 0.32748502 |
106 | MAP3K1 | 0.32707718 |
107 | PRKCA | 0.30835107 |
108 | EGFR | 0.30559326 |
109 | MAP4K2 | 0.28411186 |
110 | LRRK2 | 0.27561982 |
111 | CAMK2A | 0.25934403 |
112 | TAOK1 | 0.25757627 |
113 | RPS6KA1 | 0.25447258 |
114 | VRK1 | 0.24126228 |
115 | CDK4 | 0.23934899 |
116 | FLT3 | 0.23723577 |
117 | FGR | 0.23628891 |
118 | PTK6 | 0.23450245 |
119 | MATK | 0.22443219 |
120 | MAPK11 | 0.22215593 |
121 | IGF1R | 0.21513667 |
122 | ROCK1 | 0.20377905 |
123 | PRKCE | 0.20066428 |
124 | DMPK | 0.19489546 |
125 | ERBB2 | 0.17899272 |
126 | PRKACA | 0.17778501 |
127 | PTK2B | 0.17740638 |
128 | INSR | 0.17739347 |
129 | FYN | 0.17434244 |
130 | PRKACG | 0.17373869 |
131 | PRKCB | 0.16788353 |
132 | MAP3K11 | 0.16708463 |
133 | ILK | 0.16647098 |
134 | RPS6KA5 | 0.14130486 |
135 | BMPR1B | 0.13733041 |
136 | SRC | 0.13299547 |
137 | KSR2 | 0.12683208 |
138 | MAP2K6 | 0.11897643 |
139 | RIPK1 | 0.09546906 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 5.61599591 |
2 | Allograft rejection_Homo sapiens_hsa05330 | 4.99799690 |
3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.29644469 |
4 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.23452757 |
5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00172749 |
6 | * Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.72254950 |
7 | Leishmaniasis_Homo sapiens_hsa05140 | 2.67928597 |
8 | * Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.56466407 |
9 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.49656969 |
10 | Measles_Homo sapiens_hsa05162 | 2.49477506 |
11 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.44249601 |
12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.38213453 |
13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.18080937 |
14 | Viral myocarditis_Homo sapiens_hsa05416 | 1.92794025 |
15 | Legionellosis_Homo sapiens_hsa05134 | 1.90213139 |
16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.89935117 |
17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.89254862 |
18 | Pertussis_Homo sapiens_hsa05133 | 1.85385678 |
19 | * NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.83880180 |
20 | * Influenza A_Homo sapiens_hsa05164 | 1.82340336 |
21 | * Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.78214164 |
22 | Asthma_Homo sapiens_hsa05310 | 1.77752063 |
23 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.76015781 |
24 | Malaria_Homo sapiens_hsa05144 | 1.75484862 |
25 | * TNF signaling pathway_Homo sapiens_hsa04668 | 1.71653321 |
26 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.70864495 |
27 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.69742676 |
28 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.68129590 |
29 | * Herpes simplex infection_Homo sapiens_hsa05168 | 1.61227519 |
30 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.48883707 |
31 | Tuberculosis_Homo sapiens_hsa05152 | 1.48831028 |
32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.48150533 |
33 | * Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.45736866 |
34 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.31101143 |
35 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.25100251 |
36 | Salmonella infection_Homo sapiens_hsa05132 | 1.22681506 |
37 | Apoptosis_Homo sapiens_hsa04210 | 1.20480643 |
38 | * Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.12861464 |
39 | Shigellosis_Homo sapiens_hsa05131 | 1.11189012 |
40 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.09150028 |
41 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.04788592 |
42 | Hepatitis B_Homo sapiens_hsa05161 | 0.98156708 |
43 | Hepatitis C_Homo sapiens_hsa05160 | 0.89358969 |
44 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.81167846 |
45 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.80502979 |
46 | Proteasome_Homo sapiens_hsa03050 | 0.78572773 |
47 | Phagosome_Homo sapiens_hsa04145 | 0.72758229 |
48 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.72315028 |
49 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.70275831 |
50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69503536 |
51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.68377447 |
52 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.64808804 |
53 | Lysosome_Homo sapiens_hsa04142 | 0.63322928 |
54 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.61355613 |
55 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.61217177 |
56 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.59458269 |
57 | Amoebiasis_Homo sapiens_hsa05146 | 0.59164485 |
58 | * Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.59085794 |
59 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.56455072 |
60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.55304104 |
61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54584579 |
62 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47755534 |
63 | Parkinsons disease_Homo sapiens_hsa05012 | 0.47108486 |
64 | Phototransduction_Homo sapiens_hsa04744 | 0.46381175 |
65 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44756255 |
66 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.43319995 |
67 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.42512760 |
68 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.42076995 |
69 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.41584325 |
70 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.40869953 |
71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.40311575 |
72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.40270575 |
73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.40122537 |
74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39807877 |
75 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.38157472 |
76 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37040273 |
77 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.36393987 |
78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.36229249 |
79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.31763557 |
80 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.31368131 |
81 | Platelet activation_Homo sapiens_hsa04611 | 0.29708472 |
82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.29551919 |
83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.27189810 |
84 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.26965882 |
85 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.24909439 |
86 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.24831487 |
87 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24280586 |
88 | ABC transporters_Homo sapiens_hsa02010 | 0.24144620 |
89 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.23432949 |
90 | Alzheimers disease_Homo sapiens_hsa05010 | 0.23338907 |
91 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.23273346 |
92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.22280977 |
93 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.20427117 |
94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.20159965 |
95 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.19047323 |
96 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.18991882 |
97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.16874169 |
98 | Peroxisome_Homo sapiens_hsa04146 | 0.15950740 |
99 | Other glycan degradation_Homo sapiens_hsa00511 | 0.15777070 |
100 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.15426989 |
101 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.14674096 |
102 | * Prion diseases_Homo sapiens_hsa05020 | 0.14500820 |
103 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.13734232 |
104 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.13708997 |
105 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.13477939 |
106 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.08588088 |
107 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.06662332 |
108 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.06511100 |
109 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.06105702 |
110 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.05765371 |
111 | Mineral absorption_Homo sapiens_hsa04978 | 0.05434903 |
112 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.05084123 |
113 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.04530060 |
114 | Bladder cancer_Homo sapiens_hsa05219 | 0.04298187 |
115 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.03478658 |
116 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.03339273 |
117 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.03260355 |
118 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.03026998 |
119 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.02644435 |
120 | Morphine addiction_Homo sapiens_hsa05032 | 0.02264532 |
121 | Insulin resistance_Homo sapiens_hsa04931 | 0.02125868 |
122 | Adherens junction_Homo sapiens_hsa04520 | 0.01019572 |
123 | Endocytosis_Homo sapiens_hsa04144 | 0.00885374 |
124 | Pathways in cancer_Homo sapiens_hsa05200 | -0.0321704 |
125 | Ras signaling pathway_Homo sapiens_hsa04014 | -0.0320363 |
126 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.0180065 |
127 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | -0.0001983 |