Rank | Gene Set | Z-score |
---|---|---|
1 | lymph vessel development (GO:0001945) | 6.61646768 |
2 | endothelium development (GO:0003158) | 5.55104948 |
3 | vascular endothelial growth factor signaling pathway (GO:0038084) | 5.37488848 |
4 | blood vessel maturation (GO:0001955) | 5.19611660 |
5 | low-density lipoprotein particle clearance (GO:0034383) | 4.96824876 |
6 | surfactant homeostasis (GO:0043129) | 4.91666765 |
7 | positive regulation of vasculogenesis (GO:2001214) | 4.78482505 |
8 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 4.66506363 |
9 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 4.50721911 |
10 | regulation of endothelial cell differentiation (GO:0045601) | 4.36688393 |
11 | morphogenesis of an endothelium (GO:0003159) | 4.35155776 |
12 | endothelial tube morphogenesis (GO:0061154) | 4.35155776 |
13 | positive regulation of protein kinase C signaling (GO:0090037) | 4.30774155 |
14 | heart trabecula formation (GO:0060347) | 4.29637494 |
15 | regulation of vasculogenesis (GO:2001212) | 4.27654442 |
16 | endothelial cell morphogenesis (GO:0001886) | 4.25250677 |
17 | ovulation from ovarian follicle (GO:0001542) | 4.14315554 |
18 | venous blood vessel morphogenesis (GO:0048845) | 4.11754593 |
19 | lymphangiogenesis (GO:0001946) | 4.08121240 |
20 | hyaluronan catabolic process (GO:0030214) | 3.92344539 |
21 | cardiac myofibril assembly (GO:0055003) | 3.90322477 |
22 | patterning of blood vessels (GO:0001569) | 3.90031411 |
23 | cAMP biosynthetic process (GO:0006171) | 3.87655751 |
24 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 3.82458748 |
25 | chemical homeostasis within a tissue (GO:0048875) | 3.76669867 |
26 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 3.75280937 |
27 | positive regulation of urine volume (GO:0035810) | 3.68779701 |
28 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.67956575 |
29 | sarcomere organization (GO:0045214) | 3.66993239 |
30 | basement membrane organization (GO:0071711) | 3.63979838 |
31 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.62086921 |
32 | fatty acid transmembrane transport (GO:1902001) | 3.61495102 |
33 | definitive hemopoiesis (GO:0060216) | 3.54375463 |
34 | transcytosis (GO:0045056) | 3.53041692 |
35 | blood vessel endothelial cell migration (GO:0043534) | 3.50895126 |
36 | negative regulation of endothelial cell migration (GO:0010596) | 3.48936154 |
37 | endothelial cell chemotaxis (GO:0035767) | 3.48055573 |
38 | negative regulation of platelet activation (GO:0010544) | 3.42311117 |
39 | glomerular filtration (GO:0003094) | 3.41378054 |
40 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.41164630 |
41 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.39192891 |
42 | cellular response to cadmium ion (GO:0071276) | 3.38252900 |
43 | endothelial cell differentiation (GO:0045446) | 3.38062549 |
44 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 3.36418355 |
45 | myofibril assembly (GO:0030239) | 3.35540799 |
46 | complement activation, alternative pathway (GO:0006957) | 3.35067053 |
47 | vasculogenesis (GO:0001570) | 3.32433009 |
48 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.32290248 |
49 | negative regulation of amino acid transport (GO:0051956) | 3.31271364 |
50 | negative regulation of blood vessel endothelial cell migration (GO:0043537) | 3.31003276 |
51 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.30677434 |
52 | carnitine shuttle (GO:0006853) | 3.30052811 |
53 | plasma membrane repair (GO:0001778) | 3.26358567 |
54 | diacylglycerol metabolic process (GO:0046339) | 3.25613950 |
55 | renal filtration (GO:0097205) | 3.24535305 |
56 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.23938861 |
57 | protein kinase C signaling (GO:0070528) | 3.20484431 |
58 | response to dietary excess (GO:0002021) | 3.19973850 |
59 | Notch signaling involved in heart development (GO:0061314) | 3.19760977 |
60 | regulation of actin filament-based movement (GO:1903115) | 3.15748234 |
61 | angiogenesis involved in wound healing (GO:0060055) | 3.14491034 |
62 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.11867751 |
63 | axon extension involved in axon guidance (GO:0048846) | 3.11867751 |
64 | regulation of female gonad development (GO:2000194) | 3.08607728 |
65 | regulation of p38MAPK cascade (GO:1900744) | 3.07410389 |
66 | barbed-end actin filament capping (GO:0051016) | 3.02563660 |
67 | regulation of sequestering of triglyceride (GO:0010889) | 3.01454146 |
68 | cGMP-mediated signaling (GO:0019934) | 2.98972991 |
69 | muscle filament sliding (GO:0030049) | 2.96968013 |
70 | actin-myosin filament sliding (GO:0033275) | 2.96968013 |
71 | positive regulation of heat generation (GO:0031652) | 2.96243509 |
72 | fatty acid beta-oxidation (GO:0006635) | 2.95798703 |
73 | semaphorin-plexin signaling pathway (GO:0071526) | 2.95335413 |
74 | regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) | 2.93583137 |
75 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.91518525 |
76 | sprouting angiogenesis (GO:0002040) | 2.90525792 |
77 | regulation of sarcomere organization (GO:0060297) | 2.90179105 |
78 | establishment of endothelial barrier (GO:0061028) | 2.88253212 |
79 | labyrinthine layer development (GO:0060711) | 2.86426054 |
80 | negative regulation of focal adhesion assembly (GO:0051895) | 2.85844032 |
81 | negative regulation of cell junction assembly (GO:1901889) | 2.85844032 |
82 | negative regulation of adherens junction organization (GO:1903392) | 2.85844032 |
83 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 2.84288859 |
84 | lysine metabolic process (GO:0006553) | 2.82142470 |
85 | lysine catabolic process (GO:0006554) | 2.82142470 |
86 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 2.81372514 |
87 | endothelial cell migration (GO:0043542) | 2.80769815 |
88 | cardiac muscle tissue morphogenesis (GO:0055008) | 2.79840105 |
89 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 2.79549099 |
90 | NADH metabolic process (GO:0006734) | 2.79330390 |
91 | 2-oxoglutarate metabolic process (GO:0006103) | 2.79107209 |
92 | cardiac muscle cell proliferation (GO:0060038) | 2.77022942 |
93 | regulation of fever generation (GO:0031620) | 2.76383951 |
94 | regulation of cholesterol storage (GO:0010885) | 2.75924341 |
95 | virion attachment to host cell (GO:0019062) | 2.75819861 |
96 | adhesion of symbiont to host cell (GO:0044650) | 2.75819861 |
97 | negative regulation of DNA biosynthetic process (GO:2000279) | 2.75222059 |
98 | regulation of protein kinase C signaling (GO:0090036) | 2.74122908 |
99 | negative regulation of endothelial cell apoptotic process (GO:2000352) | 2.73696781 |
100 | regulation of urine volume (GO:0035809) | 2.73596959 |
101 | cell migration involved in heart development (GO:0060973) | 2.73472678 |
102 | arginine catabolic process (GO:0006527) | 2.70362568 |
103 | blood vessel remodeling (GO:0001974) | 2.69917337 |
104 | negative regulation of macrophage differentiation (GO:0045650) | 2.69882379 |
105 | regulation of macrophage chemotaxis (GO:0010758) | 2.68581829 |
106 | actin-mediated cell contraction (GO:0070252) | 2.67843533 |
107 | regulation of phospholipid biosynthetic process (GO:0071071) | 2.67239369 |
108 | adherens junction assembly (GO:0034333) | 2.66768149 |
109 | coronary vasculature morphogenesis (GO:0060977) | 2.66093105 |
110 | cholesterol catabolic process (GO:0006707) | 2.64969572 |
111 | sterol catabolic process (GO:0016127) | 2.64969572 |
112 | regulation of relaxation of muscle (GO:1901077) | 2.63461591 |
113 | negative regulation of endothelial cell proliferation (GO:0001937) | 2.63336149 |
114 | fatty acid oxidation (GO:0019395) | 2.62896521 |
115 | neuron remodeling (GO:0016322) | 2.62662302 |
116 | cardiac muscle contraction (GO:0060048) | 2.62103923 |
117 | regulation of vascular permeability (GO:0043114) | 2.61065885 |
118 | mRNA transcription (GO:0009299) | 2.60264132 |
119 | regulation of complement activation (GO:0030449) | 2.60192138 |
120 | regulation of the force of heart contraction (GO:0002026) | 2.59442825 |
121 | regulation of protein activation cascade (GO:2000257) | 2.58603330 |
122 | regulation of blood vessel endothelial cell migration (GO:0043535) | 2.58429177 |
123 | embryonic heart tube development (GO:0035050) | 2.57257890 |
124 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 2.57085667 |
125 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.56747111 |
126 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.55884358 |
127 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.55778200 |
128 | lipid oxidation (GO:0034440) | 2.55614667 |
129 | epoxygenase P450 pathway (GO:0019373) | 2.55195220 |
130 | negative regulation of epithelial cell migration (GO:0010633) | 2.54837077 |
131 | actomyosin structure organization (GO:0031032) | 2.54814078 |
132 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.54704165 |
133 | regulation of DNA methylation (GO:0044030) | 2.54681105 |
134 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.54584748 |
135 | paraxial mesoderm development (GO:0048339) | 2.53793864 |
136 | ganglion development (GO:0061548) | 2.53464747 |
137 | response to mercury ion (GO:0046689) | 2.53413854 |
138 | regulation of mononuclear cell migration (GO:0071675) | 2.52988361 |
139 | carnitine transmembrane transport (GO:1902603) | 2.52975489 |
140 | carnitine metabolic process (GO:0009437) | 2.52900456 |
141 | ovulation (GO:0030728) | 2.52489945 |
142 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.52430529 |
143 | negative regulation of vascular permeability (GO:0043116) | 2.52209407 |
144 | muscle tissue morphogenesis (GO:0060415) | 2.51526935 |
145 | positive regulation of lipid storage (GO:0010884) | 2.50826576 |
146 | tricarboxylic acid cycle (GO:0006099) | 2.49560554 |
147 | cardiac muscle hypertrophy (GO:0003300) | 2.48981677 |
148 | regulation of endothelial cell migration (GO:0010594) | 2.47482989 |
149 | adhesion of symbiont to host (GO:0044406) | 2.47329138 |
150 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 2.45485736 |
151 | regulation of synapse maturation (GO:0090128) | 2.45210905 |
152 | heart contraction (GO:0060047) | 2.44484629 |
153 | heart process (GO:0003015) | 2.44484629 |
154 | positive regulation of glomerulus development (GO:0090193) | 2.43296478 |
155 | polyol transport (GO:0015791) | 2.41124858 |
156 | negative regulation of heart growth (GO:0061117) | 2.40956333 |
157 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 2.40956333 |
158 | growth hormone secretion (GO:0030252) | 2.40627198 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 6.13050752 |
2 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 4.82348442 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.53907244 |
4 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.35622489 |
5 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 3.34697406 |
6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.32585418 |
7 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 3.24540514 |
8 | CLOCK_20551151_ChIP-Seq_293T_Human | 3.16899489 |
9 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.04585676 |
10 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.04585676 |
11 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.04585676 |
12 | GATA1_22025678_ChIP-Seq_K562_Human | 2.95161283 |
13 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.94786357 |
14 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.93438777 |
15 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.78408535 |
16 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.67821236 |
17 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.43883097 |
18 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.40853511 |
19 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.38897880 |
20 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.38188630 |
21 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.36958677 |
22 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.30805966 |
23 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.29352872 |
24 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.10947288 |
25 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.10947288 |
26 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.07296745 |
27 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.06564407 |
28 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.97818728 |
29 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.97408535 |
30 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.94362676 |
31 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.92608100 |
32 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.90147529 |
33 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.79182737 |
34 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.75221522 |
35 | GATA1_19941826_ChIP-Seq_K562_Human | 1.70540696 |
36 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.70333748 |
37 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.64678654 |
38 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.63539925 |
39 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.61904972 |
40 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.61559797 |
41 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.60867499 |
42 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.59901604 |
43 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59438778 |
44 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.49631255 |
45 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.49580293 |
46 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.46504595 |
47 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.45693298 |
48 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.44241613 |
49 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.41666495 |
50 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.40321924 |
51 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.39952805 |
52 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.39708613 |
53 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.39605753 |
54 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.39605753 |
55 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.39023564 |
56 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.38782705 |
57 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.37747174 |
58 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.35656461 |
59 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.34387091 |
60 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.31111829 |
61 | GATA2_19941826_ChIP-Seq_K562_Human | 1.31071974 |
62 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.29915525 |
63 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.28563983 |
64 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.28539509 |
65 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.27467891 |
66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.24189348 |
67 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.23543236 |
68 | SPI1_23127762_ChIP-Seq_K562_Human | 1.22313604 |
69 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.21381193 |
70 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.19812036 |
71 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.18769562 |
72 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.18714506 |
73 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.17739284 |
74 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16860999 |
75 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.16677845 |
76 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16570897 |
77 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.16536324 |
78 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.16318810 |
79 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.15724500 |
80 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.15199939 |
81 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.14536749 |
82 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.14170194 |
83 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.11652085 |
84 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11265262 |
85 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.10948816 |
86 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.10770334 |
87 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.10311607 |
88 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.09532133 |
89 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.09163225 |
90 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.09054907 |
91 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08974791 |
92 | P68_20966046_ChIP-Seq_HELA_Human | 1.08941190 |
93 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.06849180 |
94 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.06537754 |
95 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.06511458 |
96 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.05784576 |
97 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.05383621 |
98 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.05287177 |
99 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.05142216 |
100 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.04826682 |
101 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.04609780 |
102 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.04506490 |
103 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.04166840 |
104 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.03880038 |
105 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.03079572 |
106 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.02930224 |
107 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.02854146 |
108 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.00696241 |
109 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.00356182 |
110 | KDM2B_26808549_Chip-Seq_K562_Human | 1.00088704 |
111 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.98264094 |
112 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97955348 |
113 | CJUN_26792858_Chip-Seq_BT549_Human | 0.97600330 |
114 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.97209552 |
115 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.96989825 |
116 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 0.96714648 |
117 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.96138329 |
118 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.95549629 |
119 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93825355 |
120 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.92275426 |
121 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.92074660 |
122 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.91873798 |
123 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.91858342 |
124 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.91207780 |
125 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.90971083 |
126 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.90256618 |
127 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.90067935 |
128 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.88715270 |
129 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.88443843 |
130 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.88435776 |
131 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.87821879 |
132 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.87666273 |
133 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.87641806 |
134 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.86513842 |
135 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.86049681 |
136 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.85749885 |
137 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.85692890 |
138 | MAF_26560356_Chip-Seq_TH1_Human | 0.85380881 |
139 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.85161099 |
140 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.84946736 |
141 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.83960567 |
142 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.83943888 |
143 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.82533319 |
144 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.81635306 |
145 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.81622615 |
146 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80822146 |
147 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.79937655 |
148 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.79797301 |
149 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.78871199 |
150 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.78821832 |
151 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77520182 |
152 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.76529665 |
153 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.75333157 |
154 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.74947250 |
155 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.74896953 |
156 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.74853652 |
157 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.74696029 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010368_abnormal_lymphatic_system | 6.42438527 |
2 | MP0001879_abnormal_lymphatic_vessel | 4.78716536 |
3 | MP0005167_abnormal_blood-brain_barrier | 4.48828507 |
4 | MP0004084_abnormal_cardiac_muscle | 3.98821564 |
5 | MP0004272_abnormal_basement_membrane | 3.03282718 |
6 | MP0002837_dystrophic_cardiac_calcinosis | 2.93124099 |
7 | MP0003828_pulmonary_edema | 2.92059229 |
8 | MP0004036_abnormal_muscle_relaxation | 2.72896159 |
9 | MP0000751_myopathy | 2.55652020 |
10 | MP0003724_increased_susceptibility_to | 2.47354110 |
11 | MP0006138_congestive_heart_failure | 2.45726859 |
12 | MP0004215_abnormal_myocardial_fiber | 2.40161416 |
13 | MP0005330_cardiomyopathy | 2.23761783 |
14 | MP0002254_reproductive_system_inflammat | 2.23333714 |
15 | MP0000767_abnormal_smooth_muscle | 2.08351879 |
16 | MP0005385_cardiovascular_system_phenoty | 2.05014008 |
17 | MP0001544_abnormal_cardiovascular_syste | 2.05014008 |
18 | MP0005360_urolithiasis | 2.02680760 |
19 | MP0005058_abnormal_lysosome_morphology | 2.01009790 |
20 | MP0005409_darkened_coat_color | 1.98512078 |
21 | MP0008775_abnormal_heart_ventricle | 1.98154563 |
22 | MP0003191_abnormal_cellular_cholesterol | 1.95242949 |
23 | MP0009840_abnormal_foam_cell | 1.94634022 |
24 | MP0010630_abnormal_cardiac_muscle | 1.94090347 |
25 | MP0003279_aneurysm | 1.91004056 |
26 | MP0004147_increased_porphyrin_level | 1.88971717 |
27 | MP0003646_muscle_fatigue | 1.83797922 |
28 | MP0004130_abnormal_muscle_cell | 1.81358568 |
29 | MP0002972_abnormal_cardiac_muscle | 1.77206000 |
30 | MP0003705_abnormal_hypodermis_morpholog | 1.73707765 |
31 | MP0005085_abnormal_gallbladder_physiolo | 1.71008483 |
32 | MP0004484_altered_response_of | 1.70371316 |
33 | MP0000749_muscle_degeneration | 1.68223657 |
34 | MP0002138_abnormal_hepatobiliary_system | 1.67884734 |
35 | MP0003950_abnormal_plasma_membrane | 1.63331631 |
36 | MP0000343_altered_response_to | 1.61145621 |
37 | MP0004087_abnormal_muscle_fiber | 1.61059358 |
38 | MP0000249_abnormal_blood_vessel | 1.59698573 |
39 | MP0008875_abnormal_xenobiotic_pharmacok | 1.56458347 |
40 | MP0008004_abnormal_stomach_pH | 1.52581700 |
41 | MP0004085_abnormal_heartbeat | 1.51814937 |
42 | MP0002139_abnormal_hepatobiliary_system | 1.49754839 |
43 | MP0005165_increased_susceptibility_to | 1.47828443 |
44 | MP0005620_abnormal_muscle_contractility | 1.45815082 |
45 | MP0005670_abnormal_white_adipose | 1.42555318 |
46 | MP0002128_abnormal_blood_circulation | 1.42339970 |
47 | MP0006054_spinal_hemorrhage | 1.40385447 |
48 | MP0002127_abnormal_cardiovascular_syste | 1.40278355 |
49 | MP0004510_myositis | 1.38076087 |
50 | MP0009278_abnormal_bone_marrow | 1.37436634 |
51 | MP0005451_abnormal_body_composition | 1.36560655 |
52 | MP0002332_abnormal_exercise_endurance | 1.35052086 |
53 | MP0005365_abnormal_bile_salt | 1.34341856 |
54 | MP0001849_ear_inflammation | 1.31242576 |
55 | MP0002108_abnormal_muscle_morphology | 1.29563458 |
56 | MP0003566_abnormal_cell_adhesion | 1.28994826 |
57 | MP0004185_abnormal_adipocyte_glucose | 1.26729276 |
58 | MP0003690_abnormal_glial_cell | 1.25672509 |
59 | MP0001958_emphysema | 1.25312957 |
60 | MP0010329_abnormal_lipoprotein_level | 1.25280925 |
61 | MP0000003_abnormal_adipose_tissue | 1.23296957 |
62 | MP0000750_abnormal_muscle_regeneration | 1.21942761 |
63 | MP0005595_abnormal_vascular_smooth | 1.20264843 |
64 | MP0003567_abnormal_fetal_cardiomyocyte | 1.19887700 |
65 | MP0004233_abnormal_muscle_weight | 1.19547047 |
66 | MP0009697_abnormal_copulation | 1.19450685 |
67 | MP0002106_abnormal_muscle_physiology | 1.17114311 |
68 | MP0001614_abnormal_blood_vessel | 1.13289506 |
69 | MP0009379_abnormal_foot_pigmentation | 1.11505911 |
70 | MP0000465_gastrointestinal_hemorrhage | 1.11422498 |
71 | MP0005083_abnormal_biliary_tract | 1.11197191 |
72 | MP0010030_abnormal_orbit_morphology | 1.10966494 |
73 | MP0002925_abnormal_cardiovascular_devel | 1.09614552 |
74 | MP0000013_abnormal_adipose_tissue | 1.06969414 |
75 | MP0000266_abnormal_heart_morphology | 1.06916330 |
76 | MP0000230_abnormal_systemic_arterial | 1.06313801 |
77 | MP0004782_abnormal_surfactant_physiolog | 1.05393416 |
78 | MP0002998_abnormal_bone_remodeling | 1.02438495 |
79 | MP0003718_maternal_effect | 1.00855376 |
80 | MP0003879_abnormal_hair_cell | 1.00321666 |
81 | MP0003252_abnormal_bile_duct | 0.99870528 |
82 | MP0003011_delayed_dark_adaptation | 0.99470990 |
83 | MP0005666_abnormal_adipose_tissue | 0.97010736 |
84 | MP0001501_abnormal_sleep_pattern | 0.96866449 |
85 | MP0003186_abnormal_redox_activity | 0.96136036 |
86 | MP0002933_joint_inflammation | 0.95234398 |
87 | MP0004883_abnormal_blood_vessel | 0.94749260 |
88 | MP0005319_abnormal_enzyme/_coenzyme | 0.91699081 |
89 | MP0003453_abnormal_keratinocyte_physiol | 0.91465832 |
90 | MP0005369_muscle_phenotype | 0.91331931 |
91 | MP0005084_abnormal_gallbladder_morpholo | 0.90076880 |
92 | MP0003091_abnormal_cell_migration | 0.89200167 |
93 | MP0005535_abnormal_body_temperature | 0.88910532 |
94 | MP0004808_abnormal_hematopoietic_stem | 0.88673856 |
95 | MP0009115_abnormal_fat_cell | 0.86408099 |
96 | MP0005166_decreased_susceptibility_to | 0.85852256 |
97 | MP0008961_abnormal_basal_metabolism | 0.85341671 |
98 | MP0003137_abnormal_impulse_conducting | 0.84123934 |
99 | MP0001545_abnormal_hematopoietic_system | 0.83618605 |
100 | MP0005397_hematopoietic_system_phenotyp | 0.83618605 |
101 | MP0000747_muscle_weakness | 0.83390831 |
102 | MP0003806_abnormal_nucleotide_metabolis | 0.81521915 |
103 | MP0006036_abnormal_mitochondrial_physio | 0.81402488 |
104 | MP0003303_peritoneal_inflammation | 0.80577164 |
105 | MP0009643_abnormal_urine_homeostasis | 0.79974166 |
106 | MP0005623_abnormal_meninges_morphology | 0.79300844 |
107 | MP0005647_abnormal_sex_gland | 0.79289384 |
108 | MP0001727_abnormal_embryo_implantation | 0.79236495 |
109 | MP0000759_abnormal_skeletal_muscle | 0.78990593 |
110 | MP0005334_abnormal_fat_pad | 0.78568116 |
111 | MP0002118_abnormal_lipid_homeostasis | 0.78332461 |
112 | MP0003941_abnormal_skin_development | 0.77296441 |
113 | MP0003638_abnormal_response/metabolism_ | 0.76479355 |
114 | MP0002295_abnormal_pulmonary_circulatio | 0.74966455 |
115 | MP0005266_abnormal_metabolism | 0.73684695 |
116 | MP0009764_decreased_sensitivity_to | 0.73217414 |
117 | MP0005164_abnormal_response_to | 0.72132779 |
118 | MP0009785_altered_susceptibility_to | 0.70930566 |
119 | MP0003948_abnormal_gas_homeostasis | 0.70718127 |
120 | MP0008874_decreased_physiological_sensi | 0.69484344 |
121 | MP0008438_abnormal_cutaneous_collagen | 0.68002983 |
122 | MP0001915_intracranial_hemorrhage | 0.67828347 |
123 | MP0003300_gastrointestinal_ulcer | 0.67315502 |
124 | MP0002269_muscular_atrophy | 0.66956844 |
125 | MP0003075_altered_response_to | 0.66884975 |
126 | MP0005375_adipose_tissue_phenotype | 0.66330754 |
127 | MP0002971_abnormal_brown_adipose | 0.64939017 |
128 | MP0002148_abnormal_hypersensitivity_rea | 0.64242187 |
129 | MP0003943_abnormal_hepatobiliary_system | 0.63933471 |
130 | MP0006276_abnormal_autonomic_nervous | 0.63564326 |
131 | MP0000609_abnormal_liver_physiology | 0.62678998 |
132 | MP0005187_abnormal_penis_morphology | 0.62519108 |
133 | MP0001784_abnormal_fluid_regulation | 0.62433975 |
134 | MP0001851_eye_inflammation | 0.62221960 |
135 | MP0005332_abnormal_amino_acid | 0.61758166 |
136 | MP0004145_abnormal_muscle_electrophysio | 0.61228631 |
137 | MP0003136_yellow_coat_color | 0.60890496 |
138 | MP0001533_abnormal_skeleton_physiology | 0.59643778 |
139 | MP0008260_abnormal_autophagy | 0.59188096 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Polycythemia (HP:0001901) | 5.91075005 |
2 | Spontaneous hematomas (HP:0007420) | 5.38019935 |
3 | Hematochezia (HP:0002573) | 4.52037836 |
4 | Sudden death (HP:0001699) | 4.44101414 |
5 | Ventricular tachycardia (HP:0004756) | 4.35117028 |
6 | Esophageal varix (HP:0002040) | 4.32826208 |
7 | Deep venous thrombosis (HP:0002625) | 4.31844554 |
8 | Muscle fiber splitting (HP:0003555) | 4.19069371 |
9 | Abnormality of the nasal mucosa (HP:0000433) | 3.88337682 |
10 | Atrial fibrillation (HP:0005110) | 3.76483362 |
11 | Nuclear cataract (HP:0100018) | 3.76277405 |
12 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 3.61801840 |
13 | Broad metatarsal (HP:0001783) | 3.58645297 |
14 | Supraventricular arrhythmia (HP:0005115) | 3.48459685 |
15 | Cerebral hemorrhage (HP:0001342) | 3.44867081 |
16 | Primary atrial arrhythmia (HP:0001692) | 3.42608765 |
17 | Calf muscle hypertrophy (HP:0008981) | 3.40086717 |
18 | Hyporeflexia of lower limbs (HP:0002600) | 3.31807200 |
19 | Supraventricular tachycardia (HP:0004755) | 3.31129705 |
20 | Lipoatrophy (HP:0100578) | 3.31085909 |
21 | Lymphangioma (HP:0100764) | 3.29727953 |
22 | Increased connective tissue (HP:0009025) | 3.26246703 |
23 | Delayed CNS myelination (HP:0002188) | 3.24394626 |
24 | Skull defect (HP:0001362) | 3.23407491 |
25 | Axonal loss (HP:0003447) | 3.14845286 |
26 | Exercise-induced myalgia (HP:0003738) | 3.13193368 |
27 | Myoglobinuria (HP:0002913) | 3.12325796 |
28 | Conjunctival telangiectasia (HP:0000524) | 3.09047702 |
29 | Spinal rigidity (HP:0003306) | 3.04924104 |
30 | Facial diplegia (HP:0001349) | 3.03399466 |
31 | Exercise-induced muscle cramps (HP:0003710) | 3.03143409 |
32 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.02197610 |
33 | Complement deficiency (HP:0004431) | 2.99495333 |
34 | Difficulty running (HP:0009046) | 2.98443335 |
35 | Muscle fiber inclusion bodies (HP:0100299) | 2.97825620 |
36 | Visceral angiomatosis (HP:0100761) | 2.97822357 |
37 | Asymmetric septal hypertrophy (HP:0001670) | 2.94453958 |
38 | Cerebral aneurysm (HP:0004944) | 2.94127122 |
39 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.92729874 |
40 | Joint hemorrhage (HP:0005261) | 2.89315895 |
41 | Right ventricular cardiomyopathy (HP:0011663) | 2.88791737 |
42 | Atrioventricular block (HP:0001678) | 2.84340302 |
43 | Rimmed vacuoles (HP:0003805) | 2.83688055 |
44 | Portal hypertension (HP:0001409) | 2.82664635 |
45 | EMG: myopathic abnormalities (HP:0003458) | 2.82515564 |
46 | Hemangiomatosis (HP:0007461) | 2.81486092 |
47 | Oligomenorrhea (HP:0000876) | 2.78326775 |
48 | Hypoglycemic coma (HP:0001325) | 2.77384755 |
49 | Dilated cardiomyopathy (HP:0001644) | 2.72184735 |
50 | Neurofibrillary tangles (HP:0002185) | 2.68726651 |
51 | Bulbar palsy (HP:0001283) | 2.68383374 |
52 | Cavernous hemangioma (HP:0001048) | 2.67560751 |
53 | Apathy (HP:0000741) | 2.61383704 |
54 | Ketoacidosis (HP:0001993) | 2.60619390 |
55 | Nemaline bodies (HP:0003798) | 2.60027431 |
56 | Subaortic stenosis (HP:0001682) | 2.58513253 |
57 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.58513253 |
58 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.58038868 |
59 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.58038868 |
60 | Abnormality of glycolipid metabolism (HP:0010969) | 2.58038868 |
61 | Absent hand (HP:0004050) | 2.56869451 |
62 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.56158776 |
63 | Heart block (HP:0012722) | 2.55327050 |
64 | Myotonia (HP:0002486) | 2.49980315 |
65 | Abnormality of the hepatic vasculature (HP:0006707) | 2.49819905 |
66 | Prolonged bleeding time (HP:0003010) | 2.49360454 |
67 | Systemic lupus erythematosus (HP:0002725) | 2.48247937 |
68 | Abnormality of the calf musculature (HP:0001430) | 2.48192183 |
69 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.45751754 |
70 | Type 1 muscle fiber predominance (HP:0003803) | 2.43799945 |
71 | Mutism (HP:0002300) | 2.41894006 |
72 | Capillary hemangiomas (HP:0005306) | 2.40501046 |
73 | Syncope (HP:0001279) | 2.40052011 |
74 | Palpitations (HP:0001962) | 2.39560466 |
75 | Rhabdomyolysis (HP:0003201) | 2.39240040 |
76 | Neck muscle weakness (HP:0000467) | 2.37588035 |
77 | Hemorrhage of the eye (HP:0011885) | 2.37125129 |
78 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.37114345 |
79 | Menorrhagia (HP:0000132) | 2.36608659 |
80 | Abnormal atrioventricular conduction (HP:0005150) | 2.36107451 |
81 | Abnormality of complement system (HP:0005339) | 2.35660421 |
82 | Stridor (HP:0010307) | 2.35569602 |
83 | Diminished motivation (HP:0000745) | 2.35492538 |
84 | Ketosis (HP:0001946) | 2.35302175 |
85 | Wrist flexion contracture (HP:0001239) | 2.35220254 |
86 | Glomerulonephritis (HP:0000099) | 2.34877187 |
87 | Pulmonary embolism (HP:0002204) | 2.32006296 |
88 | Increased variability in muscle fiber diameter (HP:0003557) | 2.31861825 |
89 | Bundle branch block (HP:0011710) | 2.28505612 |
90 | Amyloidosis (HP:0011034) | 2.28435059 |
91 | Microcytic anemia (HP:0001935) | 2.27618863 |
92 | Pulmonary artery stenosis (HP:0004415) | 2.26478763 |
93 | Foot dorsiflexor weakness (HP:0009027) | 2.23917516 |
94 | Cerebral inclusion bodies (HP:0100314) | 2.20310936 |
95 | Frequent falls (HP:0002359) | 2.20164717 |
96 | Mucosal telangiectasiae (HP:0100579) | 2.20133750 |
97 | Scapular winging (HP:0003691) | 2.19640262 |
98 | Hyperglycinuria (HP:0003108) | 2.19441917 |
99 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.18327921 |
100 | Prolonged QT interval (HP:0001657) | 2.18210705 |
101 | Hypertriglyceridemia (HP:0002155) | 2.17551206 |
102 | Neonatal death (HP:0003811) | 2.13962545 |
103 | Aneurysm (HP:0002617) | 2.12911933 |
104 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.11826208 |
105 | Abnormality of the foot musculature (HP:0001436) | 2.10803860 |
106 | Difficulty climbing stairs (HP:0003551) | 2.09010238 |
107 | Polygenic inheritance (HP:0010982) | 2.08366237 |
108 | Hyperammonemia (HP:0001987) | 2.08338844 |
109 | Loss of speech (HP:0002371) | 2.07615879 |
110 | Myopathic facies (HP:0002058) | 2.06355838 |
111 | Prolonged partial thromboplastin time (HP:0003645) | 2.06133008 |
112 | Myocardial infarction (HP:0001658) | 2.05347452 |
113 | Nonimmune hydrops fetalis (HP:0001790) | 2.05131357 |
114 | Abnormality of lateral ventricle (HP:0030047) | 2.05073425 |
115 | Nephritis (HP:0000123) | 2.03663561 |
116 | Shallow orbits (HP:0000586) | 2.03343242 |
117 | Thrombophlebitis (HP:0004418) | 2.03272420 |
118 | Limb-girdle muscle atrophy (HP:0003797) | 2.02664255 |
119 | Absent eyebrow (HP:0002223) | 2.01763907 |
120 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.00894918 |
121 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.99195021 |
122 | Dicarboxylic aciduria (HP:0003215) | 1.99195021 |
123 | Hyperlipoproteinemia (HP:0010980) | 1.98726303 |
124 | Epistaxis (HP:0000421) | 1.98526893 |
125 | Stroke (HP:0001297) | 1.98484739 |
126 | Abnormality of the intrinsic pathway (HP:0010989) | 1.98080665 |
127 | Xanthomatosis (HP:0000991) | 1.97928868 |
128 | Malignant hyperthermia (HP:0002047) | 1.95594673 |
129 | Impaired platelet aggregation (HP:0003540) | 1.95469433 |
130 | Abnormal platelet function (HP:0011869) | 1.95469433 |
131 | Distal lower limb muscle weakness (HP:0009053) | 1.95311476 |
132 | Ulnar claw (HP:0001178) | 1.95289974 |
133 | Intrahepatic cholestasis (HP:0001406) | 1.93040308 |
134 | Rapidly progressive (HP:0003678) | 1.93019778 |
135 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.89185878 |
136 | Mesangial abnormality (HP:0001966) | 1.88781921 |
137 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.88752256 |
138 | Increased muscle lipid content (HP:0009058) | 1.87656543 |
139 | Diaphragmatic weakness (HP:0009113) | 1.86109010 |
140 | Abnormality of the common coagulation pathway (HP:0010990) | 1.85747159 |
141 | Nausea (HP:0002018) | 1.84549417 |
142 | Muscular dystrophy (HP:0003560) | 1.84390914 |
143 | Adactyly (HP:0009776) | 1.82697306 |
144 | Growth hormone excess (HP:0000845) | 1.80929242 |
145 | Ventricular arrhythmia (HP:0004308) | 1.79872310 |
146 | Porencephaly (HP:0002132) | 1.79680264 |
147 | Muscle stiffness (HP:0003552) | 1.79149161 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 9.66264468 |
2 | KDR | 4.93670383 |
3 | TGFBR2 | 4.14186477 |
4 | TGFBR1 | 3.05864001 |
5 | TTN | 2.55082609 |
6 | TRIB3 | 2.46716731 |
7 | PKN2 | 2.46527184 |
8 | RIPK1 | 2.38409732 |
9 | MAP3K13 | 2.14932340 |
10 | MYLK | 2.06404520 |
11 | MAP2K3 | 2.01694618 |
12 | PTK2B | 1.94036847 |
13 | TYRO3 | 1.93605087 |
14 | LATS2 | 1.91206065 |
15 | BCKDK | 1.76715436 |
16 | TESK2 | 1.76365942 |
17 | DDR2 | 1.75923716 |
18 | ERN1 | 1.75608727 |
19 | ARAF | 1.75107670 |
20 | IRAK3 | 1.71198520 |
21 | EPHB2 | 1.66159156 |
22 | DMPK | 1.58765561 |
23 | MOS | 1.51387263 |
24 | PTK6 | 1.40747937 |
25 | MAPK12 | 1.33248008 |
26 | CDC42BPA | 1.29833223 |
27 | NME2 | 1.29366780 |
28 | PDK2 | 1.25304397 |
29 | GRK1 | 1.24518394 |
30 | MAP3K9 | 1.24451017 |
31 | PRKG2 | 1.20813801 |
32 | FGFR4 | 1.16575206 |
33 | OBSCN | 1.12484892 |
34 | PHKG2 | 1.07947576 |
35 | PHKG1 | 1.07947576 |
36 | EPHB1 | 1.06886065 |
37 | MAP3K3 | 1.05328243 |
38 | LRRK2 | 1.02844406 |
39 | PRKD1 | 1.00700701 |
40 | MAP4K1 | 0.94347155 |
41 | LMTK2 | 0.92947533 |
42 | INSRR | 0.90993787 |
43 | MAP3K11 | 0.89313188 |
44 | TAOK2 | 0.88603163 |
45 | PDK3 | 0.88512832 |
46 | PDK4 | 0.88512832 |
47 | PRKAA2 | 0.86457779 |
48 | FGFR3 | 0.86187946 |
49 | PAK4 | 0.82774398 |
50 | PDGFRA | 0.81416463 |
51 | ABL2 | 0.80173288 |
52 | MAP3K10 | 0.78434041 |
53 | CAMK1D | 0.76472165 |
54 | KSR2 | 0.76449492 |
55 | TESK1 | 0.75022335 |
56 | PKN1 | 0.74068792 |
57 | CSK | 0.72419128 |
58 | MUSK | 0.72347094 |
59 | DAPK3 | 0.72127702 |
60 | MARK2 | 0.70975504 |
61 | MAP3K7 | 0.70644243 |
62 | MST1R | 0.69901448 |
63 | MAPKAPK3 | 0.68246117 |
64 | CAMK1G | 0.67116021 |
65 | PIK3CA | 0.63359586 |
66 | RPS6KA2 | 0.63109538 |
67 | PDPK1 | 0.63032723 |
68 | TAOK1 | 0.62605464 |
69 | FER | 0.61172354 |
70 | PRKCH | 0.60707283 |
71 | CAMK4 | 0.60070555 |
72 | MARK3 | 0.59912347 |
73 | KIT | 0.59192507 |
74 | CDK9 | 0.58933708 |
75 | BRAF | 0.57414414 |
76 | PINK1 | 0.57312173 |
77 | FGR | 0.56843687 |
78 | TBK1 | 0.54764248 |
79 | MAPK7 | 0.54546642 |
80 | NEK9 | 0.53742778 |
81 | WNK4 | 0.53657457 |
82 | MET | 0.52549169 |
83 | FGFR2 | 0.52169973 |
84 | FES | 0.52109401 |
85 | NTRK3 | 0.50606454 |
86 | ILK | 0.50312236 |
87 | ICK | 0.50276840 |
88 | MAP3K14 | 0.50246144 |
89 | GRK5 | 0.50108293 |
90 | TEC | 0.49526177 |
91 | SIK1 | 0.49464600 |
92 | PRPF4B | 0.47818792 |
93 | CDK19 | 0.47368732 |
94 | DYRK3 | 0.45551376 |
95 | CSNK1A1L | 0.45095892 |
96 | PTK2 | 0.43222835 |
97 | CAMK1 | 0.43094442 |
98 | MAPK4 | 0.42388109 |
99 | NTRK1 | 0.42280149 |
100 | CDK5 | 0.42140860 |
101 | MAP3K6 | 0.40733688 |
102 | RET | 0.40710462 |
103 | ZAP70 | 0.40279212 |
104 | PDGFRB | 0.39686856 |
105 | PDK1 | 0.39522974 |
106 | MATK | 0.38241849 |
107 | CSNK1G3 | 0.37813266 |
108 | IGF1R | 0.37370523 |
109 | CSNK1G1 | 0.37245818 |
110 | AKT2 | 0.36935011 |
111 | MAP3K1 | 0.36558060 |
112 | FLT3 | 0.36328853 |
113 | PRKG1 | 0.36318797 |
114 | SGK3 | 0.36270455 |
115 | MAP2K6 | 0.35966776 |
116 | PAK1 | 0.35131384 |
117 | MTOR | 0.34974279 |
118 | IRAK4 | 0.34241000 |
119 | CHUK | 0.34138459 |
120 | EGFR | 0.33751045 |
121 | CDK6 | 0.33612084 |
122 | MARK1 | 0.32599674 |
123 | GRK7 | 0.31468068 |
124 | TRPM7 | 0.30435358 |
125 | DAPK2 | 0.30046166 |
126 | ROCK2 | 0.29571816 |
127 | JAK2 | 0.28446452 |
128 | BTK | 0.28267280 |
129 | PRKAA1 | 0.27878757 |
130 | SGK494 | 0.27703034 |
131 | SGK223 | 0.27703034 |
132 | TYK2 | 0.27251167 |
133 | CAMK2G | 0.25808340 |
134 | PRKD3 | 0.24433467 |
135 | ROCK1 | 0.24410320 |
136 | SRC | 0.24205802 |
137 | PRKACB | 0.24198790 |
138 | GSK3A | 0.24037312 |
139 | EEF2K | 0.23707950 |
140 | MAP2K2 | 0.22921326 |
141 | RPS6KA6 | 0.22350477 |
142 | IKBKE | 0.22076338 |
143 | CDK4 | 0.21944024 |
144 | TAOK3 | 0.21888762 |
145 | JAK3 | 0.21863833 |
146 | MAP2K4 | 0.21427167 |
147 | JAK1 | 0.21317764 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Fatty acid degradation_Homo sapiens_hsa00071 | 3.08801947 |
2 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.84164612 |
3 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.69927590 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.58003960 |
5 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.55765878 |
6 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.55329050 |
7 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.53731970 |
8 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.40725399 |
9 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.36573600 |
10 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.21961913 |
11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.17205630 |
12 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.08643929 |
13 | PPAR signaling pathway_Homo sapiens_hsa03320 | 2.04303134 |
14 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.98171102 |
15 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.93038123 |
16 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.88116291 |
17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.83721460 |
18 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.79612943 |
19 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.69769383 |
20 | Tight junction_Homo sapiens_hsa04530 | 1.52044856 |
21 | Salmonella infection_Homo sapiens_hsa05132 | 1.45352364 |
22 | Bile secretion_Homo sapiens_hsa04976 | 1.45346975 |
23 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.43232595 |
24 | Focal adhesion_Homo sapiens_hsa04510 | 1.41592255 |
25 | Gap junction_Homo sapiens_hsa04540 | 1.34000627 |
26 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.33215032 |
27 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.33209618 |
28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.33092280 |
29 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.32074385 |
30 | Insulin resistance_Homo sapiens_hsa04931 | 1.31599066 |
31 | Carbon metabolism_Homo sapiens_hsa01200 | 1.31272247 |
32 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.30708739 |
33 | Lysosome_Homo sapiens_hsa04142 | 1.28684034 |
34 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.26104371 |
35 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.25925023 |
36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.25118816 |
37 | Axon guidance_Homo sapiens_hsa04360 | 1.21361186 |
38 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.18518430 |
39 | Platelet activation_Homo sapiens_hsa04611 | 1.16875954 |
40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.16584112 |
41 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.16455527 |
42 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.15920145 |
43 | Peroxisome_Homo sapiens_hsa04146 | 1.14175062 |
44 | Lysine degradation_Homo sapiens_hsa00310 | 1.12567529 |
45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.12171550 |
46 | ABC transporters_Homo sapiens_hsa02010 | 1.12149118 |
47 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.08960572 |
48 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.08726141 |
49 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.02863911 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.98451894 |
51 | Histidine metabolism_Homo sapiens_hsa00340 | 0.92643637 |
52 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.91063535 |
53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.90523149 |
54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.90150741 |
55 | Amoebiasis_Homo sapiens_hsa05146 | 0.86990294 |
56 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.86814269 |
57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.86575459 |
58 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.85540582 |
59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85510785 |
60 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.82740188 |
61 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.82505094 |
62 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.79014720 |
63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.78576425 |
64 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.76775485 |
65 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.75997713 |
66 | Adherens junction_Homo sapiens_hsa04520 | 0.75810359 |
67 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.75302048 |
68 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.74626514 |
69 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.74173412 |
70 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.72942726 |
71 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.72708116 |
72 | Hepatitis C_Homo sapiens_hsa05160 | 0.71766863 |
73 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.71312146 |
74 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.70516383 |
75 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.70302913 |
76 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.70136903 |
77 | Malaria_Homo sapiens_hsa05144 | 0.70135877 |
78 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.69702306 |
79 | Legionellosis_Homo sapiens_hsa05134 | 0.67988409 |
80 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.67959868 |
81 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.67580995 |
82 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.67338701 |
83 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.66080390 |
84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64171367 |
85 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63747497 |
86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.63630829 |
87 | Circadian rhythm_Homo sapiens_hsa04710 | 0.63367705 |
88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62917182 |
89 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.62095637 |
90 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.61739793 |
91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.61507520 |
92 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.60622509 |
93 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.60214516 |
94 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.59511403 |
95 | Pertussis_Homo sapiens_hsa05133 | 0.59366487 |
96 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.57897925 |
97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.57497639 |
98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56995356 |
99 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.56471289 |
100 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.56227558 |
101 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.55506759 |
102 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.55061408 |
103 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55041339 |
104 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55039616 |
105 | Renin secretion_Homo sapiens_hsa04924 | 0.54707961 |
106 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.53233875 |
107 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51595426 |
108 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.50450596 |
109 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.50149281 |
110 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.49202171 |
111 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48994551 |
112 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48988538 |
113 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.48565346 |
114 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.48252924 |
115 | Tuberculosis_Homo sapiens_hsa05152 | 0.47347147 |
116 | Shigellosis_Homo sapiens_hsa05131 | 0.47126617 |
117 | Melanogenesis_Homo sapiens_hsa04916 | 0.46706580 |
118 | Phagosome_Homo sapiens_hsa04145 | 0.46423903 |
119 | Leishmaniasis_Homo sapiens_hsa05140 | 0.46365931 |
120 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.46301997 |
121 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.45911681 |
122 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.43536771 |
123 | Bladder cancer_Homo sapiens_hsa05219 | 0.42718621 |
124 | GABAergic synapse_Homo sapiens_hsa04727 | 0.41731039 |
125 | Prion diseases_Homo sapiens_hsa05020 | 0.40964101 |
126 | Mineral absorption_Homo sapiens_hsa04978 | 0.40727124 |
127 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.40256079 |
128 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40141738 |
129 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39851723 |
130 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.39254144 |
131 | Other glycan degradation_Homo sapiens_hsa00511 | 0.38824435 |
132 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.38722756 |
133 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.37713067 |
134 | Long-term depression_Homo sapiens_hsa04730 | 0.37567738 |
135 | Morphine addiction_Homo sapiens_hsa05032 | 0.37436758 |
136 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.36387340 |
137 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.35956925 |
138 | Pathways in cancer_Homo sapiens_hsa05200 | 0.35284266 |
139 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.34588934 |
140 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.32334868 |
141 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.31053860 |
142 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.30157251 |
143 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29485503 |
144 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.29484074 |