CCNL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of activation of Janus kinase activity (GO:0010533)5.72513008
2negative regulation of T-helper cell differentiation (GO:0045623)5.71923499
3negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)5.71923499
4activation of protein kinase A activity (GO:0034199)5.66102341
5growth hormone receptor signaling pathway (GO:0060396)5.50728393
6cAMP biosynthetic process (GO:0006171)5.03738928
7cellular response to growth hormone stimulus (GO:0071378)4.93532033
8regulation of somitogenesis (GO:0014807)4.91378881
9negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)4.90363213
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.67772288
11leukotriene biosynthetic process (GO:0019370)4.55714286
12positive regulation of RNA splicing (GO:0033120)4.52953372
13dendritic spine morphogenesis (GO:0060997)4.32412681
14positive regulation of gamma-delta T cell activation (GO:0046645)4.32258805
15tooth mineralization (GO:0034505)4.25450784
16regulation of T-helper 1 cell differentiation (GO:0045625)4.16523029
17protein K11-linked deubiquitination (GO:0035871)4.15013810
18regulation of T-helper 2 cell differentiation (GO:0045628)4.03802599
19response to muramyl dipeptide (GO:0032495)4.03538133
20negative regulation of alpha-beta T cell differentiation (GO:0046639)4.00864909
21negative regulation of type 2 immune response (GO:0002829)3.96846401
22regulation of DNA damage checkpoint (GO:2000001)3.90640716
23hepatocyte apoptotic process (GO:0097284)3.88521271
24righting reflex (GO:0060013)3.84140404
25leukotriene metabolic process (GO:0006691)3.83248800
26negative regulation of actin filament bundle assembly (GO:0032232)3.77362226
27regulation of interleukin-12 biosynthetic process (GO:0045075)3.76117453
28detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.63881108
29modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.63513928
30positive regulation by organism of defense response of other organism involved in symbiotic interact3.63513928
31modulation by symbiont of host immune response (GO:0052553)3.63513928
32positive regulation by symbiont of host defense response (GO:0052509)3.63513928
33modulation by symbiont of host defense response (GO:0052031)3.63513928
34modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.63513928
35definitive hemopoiesis (GO:0060216)3.57737500
36NIK/NF-kappaB signaling (GO:0038061)3.51824622
37JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.50133443
38sulfation (GO:0051923)3.44187056
39protein prenylation (GO:0018342)3.42332157
40prenylation (GO:0097354)3.42332157
41neutrophil activation involved in immune response (GO:0002283)3.31960740
42regulation of B cell receptor signaling pathway (GO:0050855)3.27856071
43regulation of gamma-delta T cell activation (GO:0046643)3.24351888
44positive regulation of B cell differentiation (GO:0045579)3.23633249
45positive thymic T cell selection (GO:0045059)3.21275534
46myeloid dendritic cell activation (GO:0001773)3.16498868
47antigen processing and presentation of endogenous antigen (GO:0019883)3.15780984
48antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.13589582
49antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.13589582
50neutrophil activation (GO:0042119)3.12571355
51interferon-gamma production (GO:0032609)3.09658832
52germinal center formation (GO:0002467)3.08093656
53positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.07570176
54immunoglobulin mediated immune response (GO:0016064)3.05761472
55negative regulation of alpha-beta T cell activation (GO:0046636)3.05035554
56regulation of gamma-delta T cell differentiation (GO:0045586)3.03557968
57response to peptidoglycan (GO:0032494)2.99100247
58regulation of B cell differentiation (GO:0045577)2.98175423
59macrophage activation involved in immune response (GO:0002281)2.97941067
60pathway-restricted SMAD protein phosphorylation (GO:0060389)2.92362362
61cAMP metabolic process (GO:0046058)2.91260690
62regulation of interferon-beta biosynthetic process (GO:0045357)2.90473261
63response to host immune response (GO:0052572)2.90087335
64response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.90087335
65granulocyte activation (GO:0036230)2.88094726
66B cell homeostasis (GO:0001782)2.88024381
67positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.87683127
68negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.87424943
69negative regulation of granulocyte differentiation (GO:0030853)2.86520530
70cytoskeletal anchoring at plasma membrane (GO:0007016)2.85747146
71positive regulation of cellular amide metabolic process (GO:0034250)2.85066653
72microglial cell activation (GO:0001774)2.83974571
73G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.82910635
74cellular response to exogenous dsRNA (GO:0071360)2.82730574
75histone H3-K36 demethylation (GO:0070544)2.81637945
76positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.81293928
77response to type I interferon (GO:0034340)2.81189915
78positive regulation of interferon-alpha production (GO:0032727)2.79720489
79CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.78992410
80T-helper cell differentiation (GO:0042093)2.78992410
81positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.78022876
82cellular response to type I interferon (GO:0071357)2.77852466
83type I interferon signaling pathway (GO:0060337)2.77852466
84response to protozoan (GO:0001562)2.76276925
85leukocyte aggregation (GO:0070486)2.75673106
86regulation of necroptotic process (GO:0060544)2.74149675
87B cell receptor signaling pathway (GO:0050853)2.73084744
88interferon-gamma-mediated signaling pathway (GO:0060333)2.71438198
89positive T cell selection (GO:0043368)2.69663531
90regulation of interleukin-6 biosynthetic process (GO:0045408)2.69582775
91chemosensory behavior (GO:0007635)2.69264169
92regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.68612178
93regulation of interferon-alpha production (GO:0032647)2.68577882
94myeloid dendritic cell differentiation (GO:0043011)2.68290902
95defense response to protozoan (GO:0042832)2.68238041
96response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.67677437
97response to host (GO:0075136)2.67677437
98response to host defenses (GO:0052200)2.67677437
99regulation of platelet aggregation (GO:0090330)2.66020970
100detection of external biotic stimulus (GO:0098581)2.64653595
101macrophage activation (GO:0042116)2.64526797
102myeloid cell activation involved in immune response (GO:0002275)2.63928583
103positive regulation of antigen processing and presentation (GO:0002579)2.63539504
104positive regulation of interleukin-1 beta secretion (GO:0050718)2.61113409
105natural killer cell activation involved in immune response (GO:0002323)2.60964668
106myeloid leukocyte activation (GO:0002274)2.57527985
107nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)2.56957654
108positive regulation of mast cell activation (GO:0033005)2.54031290
109negative regulation of B cell proliferation (GO:0030889)2.53551528
110cellular extravasation (GO:0045123)2.52918356
111regulation of germinal center formation (GO:0002634)2.52278269
112adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189)2.52021276
113replicative senescence (GO:0090399)2.51926779
114mature B cell differentiation (GO:0002335)2.50941558
115pinocytosis (GO:0006907)2.49951032
116negative regulation of cell killing (GO:0031342)2.49824967
117negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.49824967
118lymphocyte homeostasis (GO:0002260)2.49722162
119regulation of alpha-beta T cell proliferation (GO:0046640)2.48829783
120positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.48617876
121T-helper 1 type immune response (GO:0042088)2.48155612
122positive regulation of protein sumoylation (GO:0033235)2.47446341
123activated T cell proliferation (GO:0050798)2.46976105
124cyclic purine nucleotide metabolic process (GO:0052652)2.46317736
125regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.46060784
126regulation of sequestering of triglyceride (GO:0010889)2.45994105
127nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)2.45891792
128interleukin-1-mediated signaling pathway (GO:0070498)2.45266439
129cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.44881418
130T cell activation involved in immune response (GO:0002286)2.44458540
131detection of chemical stimulus involved in sensory perception (GO:0050907)2.44003347
132lymph node development (GO:0048535)2.43788042
133I-kappaB phosphorylation (GO:0007252)2.43718379
134positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.43547609
135regulation of insulin-like growth factor receptor signaling pathway (GO:0043567)2.43537095
136regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.43488118
137cytokine secretion (GO:0050663)2.43357883
138neutrophil mediated immunity (GO:0002446)2.43072924
139mast cell activation (GO:0045576)2.42937372
140detection of molecule of bacterial origin (GO:0032490)2.42715959
141T cell migration (GO:0072678)2.42536680
142positive regulation of mRNA catabolic process (GO:0061014)2.42182088
143positive regulation of B cell activation (GO:0050871)2.41820829
144negative T cell selection (GO:0043383)2.41594226
145cyclic nucleotide biosynthetic process (GO:0009190)2.40142803
146positive regulation of interleukin-12 production (GO:0032735)2.40129055
147negative thymic T cell selection (GO:0045060)2.40102187
148I-kappaB kinase/NF-kappaB signaling (GO:0007249)2.39751608
149tolerance induction (GO:0002507)2.39702716
150negative regulation of lipid storage (GO:0010888)2.39340138
151positive regulation of interleukin-1 secretion (GO:0050716)2.38880234
152lipopolysaccharide-mediated signaling pathway (GO:0031663)2.38213896
153detection of other organism (GO:0098543)2.38146317
154positive regulation of T-helper 1 type immune response (GO:0002827)2.37787876
155fatty acid derivative biosynthetic process (GO:1901570)2.37662941
156icosanoid biosynthetic process (GO:0046456)2.37662941
157monocyte chemotaxis (GO:0002548)2.37489965
158production of molecular mediator involved in inflammatory response (GO:0002532)2.37115691
159T cell differentiation involved in immune response (GO:0002292)2.36568306
160alpha-beta T cell differentiation involved in immune response (GO:0002293)2.36568306
161alpha-beta T cell activation involved in immune response (GO:0002287)2.36568306
162regulation of B cell proliferation (GO:0030888)2.36245411
163regulation of T-helper cell differentiation (GO:0045622)2.34499230
164cellular response to interleukin-15 (GO:0071350)2.32992712
165heterotypic cell-cell adhesion (GO:0034113)2.32881069
166response to UV-C (GO:0010225)2.31943614
167detection of biotic stimulus (GO:0009595)2.31509576
168positive regulation of T-helper cell differentiation (GO:0045624)2.31417831
169retina layer formation (GO:0010842)2.30225176
170negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642)2.29619771
171regulation of platelet activation (GO:0010543)2.29058541
172water transport (GO:0006833)2.28663952
173regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.26985119
174positive regulation of alpha-beta T cell differentiation (GO:0046638)2.26595076
175negative regulation of erythrocyte differentiation (GO:0045647)2.26583083
176positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.26478608
177viral mRNA export from host cell nucleus (GO:0046784)2.26101436

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.84902692
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.51833997
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.43612431
4STAT6_21828071_ChIP-Seq_BEAS2B_Human4.30400838
5EGR1_19374776_ChIP-ChIP_THP-1_Human4.13781057
6BP1_19119308_ChIP-ChIP_Hs578T_Human4.04361124
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.73996040
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.49353415
9TP63_17297297_ChIP-ChIP_HaCaT_Human3.44441618
10SCL_19346495_ChIP-Seq_HPC-7_Human3.42782855
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.41314585
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.38212785
13IRF8_27001747_Chip-Seq_BMDM_Mouse3.14037360
14MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.06920052
15HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.83586953
16NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.80475129
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.76410550
18E2F7_22180533_ChIP-Seq_HELA_Human2.70683936
19RUNX_20019798_ChIP-Seq_JUKART_Human2.70105981
20NOTCH1_21737748_ChIP-Seq_TLL_Human2.54997015
21FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.52469353
22MYB_21317192_ChIP-Seq_ERMYB_Mouse2.49758961
23Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.46406714
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.45936454
25SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.41388981
26* STAT4_19710469_ChIP-ChIP_TH1__Mouse2.40098618
27* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.30441456
28TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.25083092
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10967440
30GATA1_22025678_ChIP-Seq_K562_Human2.07698170
31* MYB_26560356_Chip-Seq_TH2_Human2.07177709
32* MYB_26560356_Chip-Seq_TH1_Human2.00114240
33IGF1R_20145208_ChIP-Seq_DFB_Human1.93512119
34AR_21572438_ChIP-Seq_LNCaP_Human1.90096475
35* SPI1_23547873_ChIP-Seq_NB4_Human1.86561642
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.83180903
37SMAD_19615063_ChIP-ChIP_OVARY_Human1.77814648
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.77732804
39* RUNX1_22412390_ChIP-Seq_EML_Mouse1.72193608
40* VDR_24763502_ChIP-Seq_THP-1_Human1.69704556
41PU_27001747_Chip-Seq_BMDM_Mouse1.69575337
42* MAF_26560356_Chip-Seq_TH1_Human1.68558146
43* GATA2_21666600_ChIP-Seq_HMVEC_Human1.68091747
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.60645161
45PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.58862471
46* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.57593419
47ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57569376
48VDR_22108803_ChIP-Seq_LS180_Human1.56684021
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54890903
50DROSHA_22980978_ChIP-Seq_HELA_Human1.54422546
51GATA1_19941826_ChIP-Seq_K562_Human1.53338773
52* SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.52965183
53* TCF7_22412390_ChIP-Seq_EML_Mouse1.50279594
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.47350316
55ESR1_21235772_ChIP-Seq_MCF-7_Human1.46560472
56FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.45033397
57MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.42434532
58* VDR_24787735_ChIP-Seq_THP-1_Human1.42173118
59SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.38728302
60SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.38728302
61ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.36976936
62GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.33577296
63EZH2_22144423_ChIP-Seq_EOC_Human1.29862927
64MYC_22102868_ChIP-Seq_BL_Human1.29655889
65GBX2_23144817_ChIP-Seq_PC3_Human1.28798813
66VDR_21846776_ChIP-Seq_THP-1_Human1.28509074
67RNF2_27304074_Chip-Seq_ESCs_Mouse1.26637108
68BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.25131710
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.24689306
70SPI1_23127762_ChIP-Seq_K562_Human1.23464416
71GATA3_27048872_Chip-Seq_THYMUS_Human1.22308499
72LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.22305822
73GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20905557
74NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.20831393
75PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.20616526
76RXR_22108803_ChIP-Seq_LS180_Human1.20227356
77JARID2_20064375_ChIP-Seq_MESCs_Mouse1.20145227
78* UTX_26944678_Chip-Seq_JUKART_Human1.18886248
79JARID2_20075857_ChIP-Seq_MESCs_Mouse1.17209125
80RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.16321955
81LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.15700070
82EGR1_23403033_ChIP-Seq_LIVER_Mouse1.14792292
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14589645
84CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14487503
85SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.13898380
86* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.13204205
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11837787
88POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11837787
89VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.11508015
90SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.11387717
91GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10139642
92AHR_22903824_ChIP-Seq_MCF-7_Human1.09798504
93SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08524710
94SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.07961793
95CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07743295
96RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.06119079
97TP63_19390658_ChIP-ChIP_HaCaT_Human1.05264200
98CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05128755
99FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03954806
100STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.03944038
101* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.01486513
102FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.01207629
103NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.01068845
104CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00482151
105SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.99297501
106GATA3_26560356_Chip-Seq_TH2_Human0.98484609
107* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97768001
108* SMAD3_21741376_ChIP-Seq_HESCs_Human0.96859003
109CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.96772618
110SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.96749346
111KDM2B_26808549_Chip-Seq_SUP-B15_Human0.94938222
112TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.94202245
113CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.93825896
114ESR1_20079471_ChIP-ChIP_T-47D_Human0.93644838
115VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.92063243
116KDM2B_26808549_Chip-Seq_REH_Human0.91885546
117MTF2_20144788_ChIP-Seq_MESCs_Mouse0.91240530
118* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91238139
119EZH2_18974828_ChIP-Seq_MESCs_Mouse0.90436547
120RNF2_18974828_ChIP-Seq_MESCs_Mouse0.90436547
121CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90206699
122BCAT_22108803_ChIP-Seq_LS180_Human0.89338252
123GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.88951391
124KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.88697670
125* EZH2_27304074_Chip-Seq_ESCs_Mouse0.88028975
126PPAR_26484153_Chip-Seq_NCI-H1993_Human0.87628486
127SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.87346053
128RNF2_27304074_Chip-Seq_NSC_Mouse0.86972543
129* SMAD3_21741376_ChIP-Seq_EPCs_Human0.86121040
130ER_23166858_ChIP-Seq_MCF-7_Human0.85809933
131CBX2_27304074_Chip-Seq_ESCs_Mouse0.85574571
132TP63_23658742_ChIP-Seq_EP156T_Human0.84949284
133SMAD4_21799915_ChIP-Seq_A2780_Human0.84810537
134PCGF2_27294783_Chip-Seq_NPCs_Mouse0.84577816
135GATA1_19941827_ChIP-Seq_MEL_Mouse0.83814923
136BMI1_23680149_ChIP-Seq_NPCS_Mouse0.82654106
137EZH2_27294783_Chip-Seq_ESCs_Mouse0.81741137
138EED_16625203_ChIP-ChIP_MESCs_Mouse0.81698912
139GF1_26923725_Chip-Seq_HPCs_Mouse0.81587664
140LXR_22158963_ChIP-Seq_LIVER_Mouse0.81454874
141TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80467681
142* CJUN_26792858_Chip-Seq_BT549_Human0.80452886
143* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.79530402
144* FOXO3_23340844_ChIP-Seq_DLD1_Human0.78390686
145ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77659647
146BRD4_25478319_ChIP-Seq_HGPS_Human0.76612029
147MAF_26560356_Chip-Seq_TH2_Human0.76488351
148CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.75374367
149TP53_16413492_ChIP-PET_HCT116_Human0.75371123
150GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.74979213
151* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.74529973
152* CDX2_20551321_ChIP-Seq_CACO-2_Human0.71459833
153* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.71204105
154GATA2_19941826_ChIP-Seq_K562_Human0.70634430
155CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.70569615
156WT1_19549856_ChIP-ChIP_CCG9911_Human0.70337402
157NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.69732103
158NFIB_24661679_ChIP-Seq_LUNG_Mouse0.69410398
159ELK1_19687146_ChIP-ChIP_HELA_Human0.69357641
160* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.68654174
161SOX9_24532713_ChIP-Seq_HFSC_Mouse0.68373962
162FLI1_27457419_Chip-Seq_LIVER_Mouse0.67941838
163CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.66725072

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005084_abnormal_gallbladder_morpholo4.97447176
2MP0001835_abnormal_antigen_presentation3.72917557
3MP0008961_abnormal_basal_metabolism3.38229982
4MP0004130_abnormal_muscle_cell3.27104514
5MP0003252_abnormal_bile_duct2.86921568
6MP0003724_increased_susceptibility_to2.60261102
7MP0003436_decreased_susceptibility_to2.57853211
8MP0005671_abnormal_response_to2.57289947
9MP0002163_abnormal_gland_morphology2.55255517
10MP0001800_abnormal_humoral_immune2.54814856
11MP0005387_immune_system_phenotype2.49606433
12MP0001790_abnormal_immune_system2.49606433
13MP0000569_abnormal_digit_pigmentation2.48935637
14MP0002148_abnormal_hypersensitivity_rea2.48512313
15MP0005000_abnormal_immune_tolerance2.48442524
16MP0009785_altered_susceptibility_to2.43580448
17MP0002452_abnormal_antigen_presenting2.43519768
18MP0000685_abnormal_immune_system2.39958859
19MP0002419_abnormal_innate_immunity2.37726960
20MP0002723_abnormal_immune_serum2.31773824
21MP0003763_abnormal_thymus_physiology2.27743102
22MP0005025_abnormal_response_to2.18912334
23MP0002166_altered_tumor_susceptibility2.18436734
24MP0002396_abnormal_hematopoietic_system2.17597286
25MP0009278_abnormal_bone_marrow2.17058895
26MP0002420_abnormal_adaptive_immunity2.16183325
27MP0001819_abnormal_immune_cell2.15296791
28MP0001853_heart_inflammation2.08885796
29MP0005451_abnormal_body_composition2.06901261
30MP0002006_tumorigenesis2.03862862
31MP0002254_reproductive_system_inflammat1.99843674
32MP0002405_respiratory_system_inflammati1.99632724
33MP0005174_abnormal_tail_pigmentation1.98937535
34MP0005220_abnormal_exocrine_pancreas1.98629008
35MP0005397_hematopoietic_system_phenotyp1.93986183
36MP0001545_abnormal_hematopoietic_system1.93986183
37MP0005464_abnormal_platelet_physiology1.93456255
38MP0002009_preneoplasia1.93207412
39MP0004947_skin_inflammation1.90747096
40MP0004808_abnormal_hematopoietic_stem1.83552654
41MP0002398_abnormal_bone_marrow1.79666166
42MP0001873_stomach_inflammation1.77993062
43MP0003828_pulmonary_edema1.75624619
44MP0005379_endocrine/exocrine_gland_phen1.74756704
45MP0010155_abnormal_intestine_physiology1.70844468
46MP0000465_gastrointestinal_hemorrhage1.67958938
47MP0000716_abnormal_immune_system1.67386297
48MP0001851_eye_inflammation1.60421080
49MP0008057_abnormal_DNA_replication1.60389516
50MP0004381_abnormal_hair_follicle1.60185597
51MP0006082_CNS_inflammation1.59957220
52MP0008995_early_reproductive_senescence1.56421816
53MP0004264_abnormal_extraembryonic_tissu1.52887804
54MP0000689_abnormal_spleen_morphology1.48158273
55MP0003011_delayed_dark_adaptation1.45057030
56MP0001845_abnormal_inflammatory_respons1.43522742
57MP0002722_abnormal_immune_system1.43023941
58MP0001533_abnormal_skeleton_physiology1.41287430
59MP0002933_joint_inflammation1.40386820
60MP0002277_abnormal_respiratory_mucosa1.38964749
61MP0003300_gastrointestinal_ulcer1.37995704
62MP0002429_abnormal_blood_cell1.36966972
63MP0003303_peritoneal_inflammation1.35647017
64MP0003656_abnormal_erythrocyte_physiolo1.35632245
65MP0004484_altered_response_of1.34017619
66MP0003448_altered_tumor_morphology1.32193669
67MP0000703_abnormal_thymus_morphology1.32042525
68MP0004510_myositis1.31868424
69MP0003045_fibrosis1.30392296
70MP0000015_abnormal_ear_pigmentation1.29003198
71MP0000383_abnormal_hair_follicle1.22783216
72MP0008007_abnormal_cellular_replicative1.21065298
73MP0002998_abnormal_bone_remodeling1.20299864
74MP0003195_calcinosis1.19324196
75MP0002132_abnormal_respiratory_system1.15567939
76MP0005075_abnormal_melanosome_morpholog1.15242981
77MP0000613_abnormal_salivary_gland1.13714260
78MP0000858_altered_metastatic_potential1.11992611
79MP0002060_abnormal_skin_morphology1.11251413
80MP0005164_abnormal_response_to1.10407158
81MP0009764_decreased_sensitivity_to1.09418975
82MP0002877_abnormal_melanocyte_morpholog1.08436952
83MP0005310_abnormal_salivary_gland1.07205216
84MP0004134_abnormal_chest_morphology1.06545212
85MP0009333_abnormal_splenocyte_physiolog1.05947494
86MP0003453_abnormal_keratinocyte_physiol1.05786942
87MP0001879_abnormal_lymphatic_vessel1.05320549
88MP0002332_abnormal_exercise_endurance1.03499372
89MP0005377_hearing/vestibular/ear_phenot1.03088765
90MP0003878_abnormal_ear_physiology1.03088765
91MP0002095_abnormal_skin_pigmentation1.02643507
92MP0008469_abnormal_protein_level1.01174423
93MP0005390_skeleton_phenotype0.99272482
94MP0010368_abnormal_lymphatic_system0.99092847
95MP0000013_abnormal_adipose_tissue0.98889603
96MP0004883_abnormal_blood_vessel0.98261285
97MP0002928_abnormal_bile_duct0.95220407
98MP0005448_abnormal_energy_balance0.94616951
99MP0003221_abnormal_cardiomyocyte_apopto0.91915218
100MP0002127_abnormal_cardiovascular_syste0.91578107
101MP0000767_abnormal_smooth_muscle0.91185505
102MP0003866_abnormal_defecation0.90256163
103MP0001270_distended_abdomen0.90029506
104MP0000490_abnormal_crypts_of0.88577539
105MP0004185_abnormal_adipocyte_glucose0.86808968
106MP0003943_abnormal_hepatobiliary_system0.86494575
107MP0001191_abnormal_skin_condition0.86134526
108MP0001216_abnormal_epidermal_layer0.84832244
109MP0002138_abnormal_hepatobiliary_system0.84825294
110MP0010307_abnormal_tumor_latency0.84675765
111MP0000371_diluted_coat_color0.84648039
112MP0010678_abnormal_skin_adnexa0.83015131
113MP0002133_abnormal_respiratory_system0.82969781
114MP0005388_respiratory_system_phenotype0.82969781
115MP0005076_abnormal_cell_differentiation0.82619029
116MP0005647_abnormal_sex_gland0.80211965
117MP0008004_abnormal_stomach_pH0.80105564
118MP0010352_gastrointestinal_tract_polyps0.79838209
119MP0004133_heterotaxia0.79765570
120MP0003183_abnormal_peptide_metabolism0.79643504
121MP0000372_irregular_coat_pigmentation0.77633468
122MP0003566_abnormal_cell_adhesion0.77581416
123MP0009115_abnormal_fat_cell0.77530389
124MP0006054_spinal_hemorrhage0.77262235
125MP0005409_darkened_coat_color0.76987319
126MP0002098_abnormal_vibrissa_morphology0.76387918
127MP0003795_abnormal_bone_structure0.75533681
128MP0005334_abnormal_fat_pad0.75053951
129MP0000750_abnormal_muscle_regeneration0.72876668
130MP0003941_abnormal_skin_development0.72765427
131MP0003191_abnormal_cellular_cholesterol0.72210506
132MP0003279_aneurysm0.72201434
133MP0002136_abnormal_kidney_physiology0.71524106
134MP0009763_increased_sensitivity_to0.71063011
135MP0004782_abnormal_surfactant_physiolog0.70821080
136MP0002139_abnormal_hepatobiliary_system0.68310846
137MP0004885_abnormal_endolymph0.67317075
138MP0003646_muscle_fatigue0.66627559
139MP0006138_congestive_heart_failure0.64679167
140MP0000249_abnormal_blood_vessel0.62897509
141MP0000343_altered_response_to0.62662446
142MP0005023_abnormal_wound_healing0.62575286
143MP0000678_abnormal_parathyroid_gland0.60384826

Predicted human phenotypes

RankGene SetZ-score
1Anomalous pulmonary venous return (HP:0010772)5.42326645
2Abnormality of the pulmonary veins (HP:0011718)4.82617995
3Recurrent abscess formation (HP:0002722)4.46004123
4Hemiplegia (HP:0002301)4.36388805
5Oral leukoplakia (HP:0002745)4.22928887
6Recurrent bacterial skin infections (HP:0005406)4.21147348
7Slow saccadic eye movements (HP:0000514)4.20068362
8Eczematoid dermatitis (HP:0000976)4.17874724
9Elevated erythrocyte sedimentation rate (HP:0003565)3.89756512
10Retrobulbar optic neuritis (HP:0100654)3.82040988
11Optic neuritis (HP:0100653)3.82040988
12Myositis (HP:0100614)3.80238028
13Diastasis recti (HP:0001540)3.74232011
14Orchitis (HP:0100796)3.64254224
15Recurrent fungal infections (HP:0002841)3.47079560
16Prostate neoplasm (HP:0100787)3.46273518
17Thoracolumbar scoliosis (HP:0002944)3.44252192
18Neoplasm of the tracheobronchial system (HP:0100552)3.37552163
19Muscle fibrillation (HP:0010546)3.35982328
20Stomatitis (HP:0010280)3.34174267
21Mediastinal lymphadenopathy (HP:0100721)3.32447465
22Vertebral arch anomaly (HP:0008438)3.31428704
23Overgrowth (HP:0001548)3.26428370
24J-shaped sella turcica (HP:0002680)3.17384178
25Abnormality of the fingertips (HP:0001211)3.16191796
26Recurrent viral infections (HP:0004429)3.04800599
27Tongue fasciculations (HP:0001308)3.02694380
28Abnormality of the odontoid process (HP:0003310)3.01155130
29Recurrent skin infections (HP:0001581)2.96712109
30Chronic mucocutaneous candidiasis (HP:0002728)2.96535279
31Recurrent cutaneous fungal infections (HP:0011370)2.96535279
32Vasculitis (HP:0002633)2.86708754
33Carpal bone hypoplasia (HP:0001498)2.79560604
34Periodontitis (HP:0000704)2.76558527
35Lip pit (HP:0100267)2.75578079
36Pathologic fracture (HP:0002756)2.73506341
37Broad ribs (HP:0000885)2.72514977
38Prolonged bleeding time (HP:0003010)2.67768010
39Flat acetabular roof (HP:0003180)2.67073399
40Deformed sella turcica (HP:0002681)2.64959660
41Abnormality of the prostate (HP:0008775)2.64435177
42Abnormality of T cell number (HP:0011839)2.63792779
43Abnormality of the axillary hair (HP:0100134)2.63225046
44Abnormality of secondary sexual hair (HP:0009888)2.63225046
45Thick nail (HP:0001805)2.60180971
46T lymphocytopenia (HP:0005403)2.59938097
47IgM deficiency (HP:0002850)2.59249410
48Genetic anticipation (HP:0003743)2.59011054
49Thyroiditis (HP:0100646)2.58960681
50Pustule (HP:0200039)2.57847182
51Gingivitis (HP:0000230)2.57599819
52Leukocytosis (HP:0001974)2.56954371
53Abnormal delayed hypersensitivity skin test (HP:0002963)2.55251332
54Autoimmune thrombocytopenia (HP:0001973)2.53281899
55Keratoconjunctivitis sicca (HP:0001097)2.52053580
56Chronic otitis media (HP:0000389)2.50972053
57Pulmonary infiltrates (HP:0002113)2.50849697
58Meningitis (HP:0001287)2.48712217
59Arterial thrombosis (HP:0004420)2.48663942
60Acute myeloid leukemia (HP:0004808)2.47780506
61Recurrent gram-negative bacterial infections (HP:0005420)2.46261447
62Cellulitis (HP:0100658)2.45582647
63Chronic diarrhea (HP:0002028)2.45349989
64Gingival bleeding (HP:0000225)2.44947341
65Generalized hypopigmentation of hair (HP:0011358)2.44547725
66Panhypogammaglobulinemia (HP:0003139)2.39660174
67Syringomyelia (HP:0003396)2.38253132
68Spinal cord lesions (HP:0100561)2.38253132
69Keratoconjunctivitis (HP:0001096)2.37619075
70Agammaglobulinemia (HP:0004432)2.37148720
71Amelogenesis imperfecta (HP:0000705)2.36036934
72Eosinophilia (HP:0001880)2.35844461
73Autoimmune hemolytic anemia (HP:0001890)2.33446469
74Recurrent bronchitis (HP:0002837)2.33154530
75Abnormality of macrophages (HP:0004311)2.30858773
76Abnormality of the lumbar spine (HP:0100712)2.29509566
77Impaired smooth pursuit (HP:0007772)2.28331151
78B lymphocytopenia (HP:0010976)2.27287744
79Abnormality of B cell number (HP:0010975)2.27287744
80Epistaxis (HP:0000421)2.27218145
81Prominent occiput (HP:0000269)2.26680472
82Gastrointestinal infarctions (HP:0005244)2.25934926
83Stomach cancer (HP:0012126)2.25470896
84Hematochezia (HP:0002573)2.23111151
85Absent frontal sinuses (HP:0002688)2.22698587
86Spontaneous hematomas (HP:0007420)2.19153476
87Hemoptysis (HP:0002105)2.18239062
88Abnormality of glycolipid metabolism (HP:0010969)2.17599006
89Abnormality of liposaccharide metabolism (HP:0010968)2.17599006
90Abnormality of glycosphingolipid metabolism (HP:0004343)2.17599006
91Thrombocytosis (HP:0001894)2.17251744
92Inflammation of the large intestine (HP:0002037)2.17082891
93Recurrent pneumonia (HP:0006532)2.17079389
94Abnormality of eosinophils (HP:0001879)2.14745869
95Chest pain (HP:0100749)2.13409648
96Petechiae (HP:0000967)2.12910675
97Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.10748528
98Osteomyelitis (HP:0002754)2.09952892
99Obstructive lung disease (HP:0006536)2.07982608
100Chronic obstructive pulmonary disease (HP:0006510)2.07982608
101Flared iliac wings (HP:0002869)2.07628445
102Granulocytopenia (HP:0001913)2.07387097
103Abnormality of T cells (HP:0002843)2.05870189
104Abnormality of the sella turcica (HP:0002679)2.04290325
105Chromsome breakage (HP:0040012)2.03875965
106Aortic regurgitation (HP:0001659)2.03456459
107Colitis (HP:0002583)2.01905615
108Abnormality of the nasal septum (HP:0000419)2.01232290
109Cheilitis (HP:0100825)1.99812134
110Ventricular fibrillation (HP:0001663)1.98852683
111Abnormality of the intervertebral disk (HP:0005108)1.97734915
112Chromosomal breakage induced by crosslinking agents (HP:0003221)1.95439608
113Lymphopenia (HP:0001888)1.94637821
114Ectropion (HP:0000656)1.94533427
115Pigmentary retinal degeneration (HP:0001146)1.93980964
116Severe combined immunodeficiency (HP:0004430)1.93849075
117Gastrointestinal inflammation (HP:0004386)1.91830959
118Hyporeflexia of lower limbs (HP:0002600)1.91774097
119IgA deficiency (HP:0002720)1.91752620
120Neonatal hypoglycemia (HP:0001998)1.91249123
121Abnormality of cells of the lymphoid lineage (HP:0012140)1.89557562
122Lymphoma (HP:0002665)1.89137923
123Anhidrosis (HP:0000970)1.88168106
124Abnormality of the renal collecting system (HP:0004742)1.87437894
125Increased IgE level (HP:0003212)1.87331253
126Osteolytic defects of the phalanges of the hand (HP:0009771)1.86184340
127Osteolytic defects of the hand bones (HP:0009699)1.86184340
128Abnormality of the frontal sinuses (HP:0002687)1.85763314
129Severe short stature (HP:0003510)1.85639650
130Recurrent lower respiratory tract infections (HP:0002783)1.85124589
131Neoplasm of the heart (HP:0100544)1.83951572
132Persistence of primary teeth (HP:0006335)1.83832329
133Abnormality of ocular smooth pursuit (HP:0000617)1.83800807
134Encephalitis (HP:0002383)1.81199378
135Keratitis (HP:0000491)1.80658074
136Abnormality of T cell physiology (HP:0011840)1.80474919
137Broad alveolar ridges (HP:0000187)1.78958100
138Disinhibition (HP:0000734)1.77915645
139Submucous cleft hard palate (HP:0000176)1.77850571
140Bronchitis (HP:0012387)1.77023821
141Cavernous hemangioma (HP:0001048)1.76655645
142Myocardial infarction (HP:0001658)1.76642606
143Alveolar cell carcinoma (HP:0006519)1.74711437
144Muscle fiber splitting (HP:0003555)1.74108487
145White forelock (HP:0002211)1.73513454
146Papilledema (HP:0001085)1.73374126
147Premature loss of primary teeth (HP:0006323)1.73135405
148Vertebral fusion (HP:0002948)1.73020914
149Leukopenia (HP:0001882)1.72449856
150Premature graying of hair (HP:0002216)1.72293361
151Abnormality of the columella (HP:0009929)1.71914143
152Pulmonary artery stenosis (HP:0004415)1.71482012
153Difficulty running (HP:0009046)1.70537885
154Hamartoma of the eye (HP:0010568)1.69784461
155Short femoral neck (HP:0100864)1.68451764
156Asplenia (HP:0001746)1.68404594
157Hypoplasia of the fovea (HP:0007750)1.68404191
158Aplasia/Hypoplasia of the fovea (HP:0008060)1.68404191
159Ovoid vertebral bodies (HP:0003300)1.67040981

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.31680037
2IRAK32.93101059
3MAP4K12.90327929
4TXK2.64456205
5IRAK42.62627325
6TGFBR22.52922035
7IKBKB2.40032537
8IKBKE2.39119431
9NTRK22.24042959
10TEC2.23455877
11TYK22.12846621
12GRK62.09739780
13JAK32.00308438
14MAP3K21.99170760
15CHUK1.93888616
16KIT1.90499778
17TBK11.87738105
18MAPK151.85875316
19ITK1.80932160
20PRPF4B1.69797552
21BTK1.67193625
22STK101.65487729
23MAP3K31.58331505
24STK241.57665271
25BRD41.49012077
26FGFR31.45429470
27BLK1.44720167
28RIPK41.43856838
29TAOK31.42135333
30MST41.40838918
31JAK11.40070822
32NLK1.36760457
33MAP2K31.31215424
34TIE11.29433806
35CSF1R1.29264403
36MAP3K131.28688347
37ZAP701.28101161
38MAP2K41.27460855
39KDR1.24890493
40CDK121.24301441
41RPS6KA41.21951288
42SIK31.21305205
43FRK1.19251464
44PIM11.19129312
45PIK3CG1.18142282
46CLK11.17997352
47NUAK11.16507730
48TRPM71.15679602
49MAP3K11.13865726
50MAP3K51.11087483
51LCK1.10458403
52HCK1.07811921
53EIF2AK21.07178619
54SYK1.06116778
55BMPR21.01769703
56MAPK70.99860877
57ZAK0.98499705
58EPHA30.97833747
59MKNK10.94196342
60MKNK20.92615487
61YES10.92132633
62CSK0.91200693
63FGFR40.90786149
64CDK60.90143987
65VRK10.89348634
66EPHB10.88059774
67STK38L0.87077896
68LYN0.86984689
69CAMK40.86155251
70SGK20.86044932
71CDK30.83517260
72NEK90.83281499
73MARK30.82641336
74ERBB30.81495181
75TLK10.81391460
76GRK50.80717343
77GRK70.80692555
78FLT30.80384524
79MAP3K60.78760696
80CDK80.77878492
81HIPK20.76652036
82MARK20.75370364
83MOS0.73259161
84PIM20.70939300
85AKT30.70656352
86RPS6KA50.70096739
87MAP2K20.69959601
88IRAK20.69563761
89STK40.68428468
90CDK90.67275718
91TAF10.66780775
92PRKD20.65892790
93IRAK10.65063782
94INSRR0.64668362
95JAK20.63319717
96RIPK10.63041950
97MAPKAPK50.61109585
98SIK20.60434185
99NEK60.60271245
100KSR20.60113087
101MAP3K70.60106131
102SGK30.59932311
103TAOK20.59588440
104OBSCN0.59015252
105MAPKAPK20.58374946
106ERBB20.58102027
107PDGFRB0.56512243
108TAOK10.54917521
109ATR0.54061042
110RPS6KA60.53435643
111ABL10.53199368
112PDK10.52417218
113MAPK120.51058974
114STK110.49742753
115FYN0.48724294
116TGFBR10.48723394
117FES0.47990517
118MAP3K110.47874288
119PRKCQ0.47389069
120WNK10.45655725
121TNIK0.45499797
122CAMK1D0.45285644
123PTK2B0.44953437
124CAMKK20.44889342
125RET0.44078618
126PRKAA20.43037242
127RPS6KB20.43006936
128SGK4940.42150954
129SGK2230.42150954
130PAK30.40917180
131MAPK30.40166410
132MAP3K100.39965393
133MAP3K40.39342874
134ERN10.38593655
135ADRBK20.38282271
136MATK0.37653062
137MAPK40.36029922
138GRK10.35810550
139MELK0.33858712
140RPS6KC10.33842789
141RPS6KL10.33842789
142IGF1R0.33066847
143CAMK1G0.31312387
144STK30.31116356
145MAPK10.31014656
146INSR0.28261213

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.84492239
2Leishmaniasis_Homo sapiens_hsa051402.59320082
3Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.45732316
4Primary immunodeficiency_Homo sapiens_hsa053402.31985843
5Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.31903120
6Osteoclast differentiation_Homo sapiens_hsa043802.29389848
7NOD-like receptor signaling pathway_Homo sapiens_hsa046212.28568422
8Graft-versus-host disease_Homo sapiens_hsa053322.16242302
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.11680359
10Measles_Homo sapiens_hsa051622.09549869
11Intestinal immune network for IgA production_Homo sapiens_hsa046722.07590896
12B cell receptor signaling pathway_Homo sapiens_hsa046622.02379307
13Hematopoietic cell lineage_Homo sapiens_hsa046401.98286150
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.93424505
15Ovarian steroidogenesis_Homo sapiens_hsa049131.92022815
16TNF signaling pathway_Homo sapiens_hsa046681.87413952
17Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.86031340
18RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.81718477
19Herpes simplex infection_Homo sapiens_hsa051681.80252839
20Allograft rejection_Homo sapiens_hsa053301.78863754
21Malaria_Homo sapiens_hsa051441.67764634
22Dorso-ventral axis formation_Homo sapiens_hsa043201.65944987
23Legionellosis_Homo sapiens_hsa051341.64103064
24Influenza A_Homo sapiens_hsa051641.61997980
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.57217428
26T cell receptor signaling pathway_Homo sapiens_hsa046601.55656803
27Toxoplasmosis_Homo sapiens_hsa051451.55523260
28Antigen processing and presentation_Homo sapiens_hsa046121.52770749
29GnRH signaling pathway_Homo sapiens_hsa049121.51810424
30Systemic lupus erythematosus_Homo sapiens_hsa053221.51235756
31Olfactory transduction_Homo sapiens_hsa047401.51140012
32Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.50847673
33Pertussis_Homo sapiens_hsa051331.49444815
34Transcriptional misregulation in cancer_Homo sapiens_hsa052021.48988242
35Staphylococcus aureus infection_Homo sapiens_hsa051501.43140272
36Apoptosis_Homo sapiens_hsa042101.41031351
37Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39941724
38Dilated cardiomyopathy_Homo sapiens_hsa054141.36679556
39Hepatitis B_Homo sapiens_hsa051611.29660585
40Longevity regulating pathway - mammal_Homo sapiens_hsa042111.27647337
41Linoleic acid metabolism_Homo sapiens_hsa005911.26695852
42Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.25201447
43Asthma_Homo sapiens_hsa053101.23296317
44Tuberculosis_Homo sapiens_hsa051521.21971756
45Salivary secretion_Homo sapiens_hsa049701.20478707
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.20189446
47Morphine addiction_Homo sapiens_hsa050321.17069207
48Bile secretion_Homo sapiens_hsa049761.13912288
49Vascular smooth muscle contraction_Homo sapiens_hsa042701.13602185
50Rheumatoid arthritis_Homo sapiens_hsa053231.13228419
51African trypanosomiasis_Homo sapiens_hsa051431.11822253
52Pancreatic secretion_Homo sapiens_hsa049721.11161557
53Autoimmune thyroid disease_Homo sapiens_hsa053201.09158243
54Chemokine signaling pathway_Homo sapiens_hsa040621.08958674
55Caffeine metabolism_Homo sapiens_hsa002321.08916900
56AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.08847621
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04713785
58Estrogen signaling pathway_Homo sapiens_hsa049151.04634167
59Acute myeloid leukemia_Homo sapiens_hsa052211.04495345
60Gap junction_Homo sapiens_hsa045401.03780791
61Cholinergic synapse_Homo sapiens_hsa047251.02950357
62Leukocyte transendothelial migration_Homo sapiens_hsa046701.02593959
63Gastric acid secretion_Homo sapiens_hsa049711.02207710
64Hepatitis C_Homo sapiens_hsa051601.02070483
65Chronic myeloid leukemia_Homo sapiens_hsa052201.01781480
66Small cell lung cancer_Homo sapiens_hsa052220.99967751
67cAMP signaling pathway_Homo sapiens_hsa040240.98079429
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.97754391
69Aldosterone synthesis and secretion_Homo sapiens_hsa049250.96318653
70HTLV-I infection_Homo sapiens_hsa051660.95960584
71Glutamatergic synapse_Homo sapiens_hsa047240.94821886
72Sulfur metabolism_Homo sapiens_hsa009200.92634446
73Taste transduction_Homo sapiens_hsa047420.92198839
74Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.91488388
75Salmonella infection_Homo sapiens_hsa051320.91369882
76Shigellosis_Homo sapiens_hsa051310.91264872
77Notch signaling pathway_Homo sapiens_hsa043300.90092571
78Platelet activation_Homo sapiens_hsa046110.88691212
79Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.88046382
80Oxytocin signaling pathway_Homo sapiens_hsa049210.87985202
81Circadian entrainment_Homo sapiens_hsa047130.86979022
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.86864434
83Adipocytokine signaling pathway_Homo sapiens_hsa049200.86633105
84Non-homologous end-joining_Homo sapiens_hsa034500.86255615
85Non-small cell lung cancer_Homo sapiens_hsa052230.85439108
86Fanconi anemia pathway_Homo sapiens_hsa034600.84416357
87Thyroid hormone synthesis_Homo sapiens_hsa049180.83251451
88Insulin secretion_Homo sapiens_hsa049110.82626133
89Type II diabetes mellitus_Homo sapiens_hsa049300.80808033
90Other glycan degradation_Homo sapiens_hsa005110.80215386
91MicroRNAs in cancer_Homo sapiens_hsa052060.78285804
92Calcium signaling pathway_Homo sapiens_hsa040200.77642514
93Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.76463854
94GABAergic synapse_Homo sapiens_hsa047270.75997188
95Epstein-Barr virus infection_Homo sapiens_hsa051690.74433240
96Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.73723431
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.73088618
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.71377399
99Prolactin signaling pathway_Homo sapiens_hsa049170.70684610
100Pancreatic cancer_Homo sapiens_hsa052120.70624760
101Renin secretion_Homo sapiens_hsa049240.70323421
102p53 signaling pathway_Homo sapiens_hsa041150.68707773
103Prostate cancer_Homo sapiens_hsa052150.67810113
104Melanogenesis_Homo sapiens_hsa049160.67724449
105Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66333999
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.65691084
107Homologous recombination_Homo sapiens_hsa034400.65248258
108Rap1 signaling pathway_Homo sapiens_hsa040150.63523802
109Type I diabetes mellitus_Homo sapiens_hsa049400.63523274
110FoxO signaling pathway_Homo sapiens_hsa040680.62694435
111Sphingolipid metabolism_Homo sapiens_hsa006000.62573811
112Insulin resistance_Homo sapiens_hsa049310.60696532
113Viral myocarditis_Homo sapiens_hsa054160.60152265
114Melanoma_Homo sapiens_hsa052180.59356890
115Viral carcinogenesis_Homo sapiens_hsa052030.59155414
116Choline metabolism in cancer_Homo sapiens_hsa052310.56773477
117Alcoholism_Homo sapiens_hsa050340.56199984
118ECM-receptor interaction_Homo sapiens_hsa045120.55564336
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55466262
120Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55081085
121Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54674158
122Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.53978537
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.53804812
124Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53725419
125mTOR signaling pathway_Homo sapiens_hsa041500.53665962
126Base excision repair_Homo sapiens_hsa034100.53477518
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53175483
128Adherens junction_Homo sapiens_hsa045200.50987499
129RNA degradation_Homo sapiens_hsa030180.49720503
130MAPK signaling pathway_Homo sapiens_hsa040100.48095142
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.47273969
132Pathways in cancer_Homo sapiens_hsa052000.46744945
133Phagosome_Homo sapiens_hsa041450.45787203
134Proteoglycans in cancer_Homo sapiens_hsa052050.45166848
135Amoebiasis_Homo sapiens_hsa051460.45114322
136TGF-beta signaling pathway_Homo sapiens_hsa043500.42926251
137ABC transporters_Homo sapiens_hsa020100.42395080
138SNARE interactions in vesicular transport_Homo sapiens_hsa041300.42157793
139Lysine degradation_Homo sapiens_hsa003100.41075074
140Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40960745
141Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.40338990
142Lysosome_Homo sapiens_hsa041420.39501094
143Arachidonic acid metabolism_Homo sapiens_hsa005900.39107862
144PI3K-Akt signaling pathway_Homo sapiens_hsa041510.38697450
145Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37835110
146Basal transcription factors_Homo sapiens_hsa030220.36533509
147DNA replication_Homo sapiens_hsa030300.35424909
148Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.34999888
149Focal adhesion_Homo sapiens_hsa045100.34879233
150Inositol phosphate metabolism_Homo sapiens_hsa005620.33935156
151Spliceosome_Homo sapiens_hsa030400.32906507
152Regulation of actin cytoskeleton_Homo sapiens_hsa048100.32792930
153Circadian rhythm_Homo sapiens_hsa047100.32066920

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