

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | B cell receptor signaling pathway (GO:0050853) | 6.25005752 |
| 2 | opioid receptor signaling pathway (GO:0038003) | 5.14915067 |
| 3 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 4.76996401 |
| 4 | positive regulation of B cell differentiation (GO:0045579) | 4.68380542 |
| 5 | cellular extravasation (GO:0045123) | 4.37022065 |
| 6 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.36463331 |
| 7 | interkinetic nuclear migration (GO:0022027) | 4.32811291 |
| 8 | regulation of germinal center formation (GO:0002634) | 4.18964141 |
| 9 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.99516979 |
| 10 | positive regulation of developmental pigmentation (GO:0048087) | 3.92939311 |
| 11 | cellular response to exogenous dsRNA (GO:0071360) | 3.92295130 |
| 12 | striated muscle atrophy (GO:0014891) | 3.90297971 |
| 13 | positive thymic T cell selection (GO:0045059) | 3.82220448 |
| 14 | nucleoside diphosphate catabolic process (GO:0009134) | 3.81864870 |
| 15 | snRNA transcription (GO:0009301) | 3.80481609 |
| 16 | muscle atrophy (GO:0014889) | 3.79968340 |
| 17 | microglial cell activation (GO:0001774) | 3.76319254 |
| 18 | skeletal muscle adaptation (GO:0043501) | 3.72027553 |
| 19 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.69722619 |
| 20 | neutrophil mediated immunity (GO:0002446) | 3.68918114 |
| 21 | positive T cell selection (GO:0043368) | 3.63012466 |
| 22 | alanine transport (GO:0032328) | 3.59459485 |
| 23 | protein K48-linked deubiquitination (GO:0071108) | 3.54978642 |
| 24 | negative thymic T cell selection (GO:0045060) | 3.54283309 |
| 25 | regulation of B cell differentiation (GO:0045577) | 3.52821850 |
| 26 | negative T cell selection (GO:0043383) | 3.45814661 |
| 27 | phosphorelay signal transduction system (GO:0000160) | 3.37436232 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.37226329 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.37226329 |
| 30 | histone H3-K9 methylation (GO:0051567) | 3.36905071 |
| 31 | reactive oxygen species biosynthetic process (GO:1903409) | 3.34078540 |
| 32 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.33549509 |
| 33 | fucose catabolic process (GO:0019317) | 3.31079231 |
| 34 | L-fucose metabolic process (GO:0042354) | 3.31079231 |
| 35 | L-fucose catabolic process (GO:0042355) | 3.31079231 |
| 36 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.27496495 |
| 37 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.24665595 |
| 38 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.24665595 |
| 39 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.24408971 |
| 40 | valine metabolic process (GO:0006573) | 3.22746060 |
| 41 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.20300992 |
| 42 | histone-serine phosphorylation (GO:0035404) | 3.18856738 |
| 43 | histone H3-K9 modification (GO:0061647) | 3.18116372 |
| 44 | regulation of pigment cell differentiation (GO:0050932) | 3.17420909 |
| 45 | cellular ketone body metabolic process (GO:0046950) | 3.13361234 |
| 46 | DNA damage response, detection of DNA damage (GO:0042769) | 3.10377252 |
| 47 | myeloid leukocyte mediated immunity (GO:0002444) | 3.07687876 |
| 48 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.06387317 |
| 49 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.04462639 |
| 50 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.02873203 |
| 51 | cellular response to ethanol (GO:0071361) | 3.02572987 |
| 52 | rRNA catabolic process (GO:0016075) | 2.98413044 |
| 53 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.97732306 |
| 54 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.95045226 |
| 55 | positive regulation of Rap GTPase activity (GO:0032854) | 2.94898643 |
| 56 | lysosome organization (GO:0007040) | 2.94724844 |
| 57 | lytic vacuole organization (GO:0080171) | 2.94724844 |
| 58 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.93670002 |
| 59 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.93501611 |
| 60 | indolalkylamine catabolic process (GO:0046218) | 2.93199463 |
| 61 | tryptophan catabolic process (GO:0006569) | 2.93199463 |
| 62 | indole-containing compound catabolic process (GO:0042436) | 2.93199463 |
| 63 | negative regulation of interleukin-8 production (GO:0032717) | 2.91056248 |
| 64 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.90836491 |
| 65 | peptidyl-lysine methylation (GO:0018022) | 2.89362343 |
| 66 | negative regulation of sodium ion transport (GO:0010766) | 2.85508056 |
| 67 | cAMP catabolic process (GO:0006198) | 2.85338088 |
| 68 | positive regulation of B cell activation (GO:0050871) | 2.82150649 |
| 69 | DNA methylation involved in gamete generation (GO:0043046) | 2.81869247 |
| 70 | megakaryocyte development (GO:0035855) | 2.80299948 |
| 71 | organ growth (GO:0035265) | 2.76935544 |
| 72 | regulation of gene expression by genetic imprinting (GO:0006349) | 2.76035517 |
| 73 | positive regulation of B cell proliferation (GO:0030890) | 2.75347973 |
| 74 | positive regulation of DNA recombination (GO:0045911) | 2.75116763 |
| 75 | ketone body metabolic process (GO:1902224) | 2.74245894 |
| 76 | regulation of chemokine biosynthetic process (GO:0045073) | 2.74000079 |
| 77 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.73006910 |
| 78 | C4-dicarboxylate transport (GO:0015740) | 2.72894849 |
| 79 | histone mRNA catabolic process (GO:0071044) | 2.72472034 |
| 80 | establishment of protein localization to Golgi (GO:0072600) | 2.68630183 |
| 81 | cyclic nucleotide catabolic process (GO:0009214) | 2.68236179 |
| 82 | respiratory burst (GO:0045730) | 2.67921860 |
| 83 | positive regulation of cytokine biosynthetic process (GO:0042108) | 2.67343725 |
| 84 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.66528094 |
| 85 | regulation of gamma-delta T cell activation (GO:0046643) | 2.66520634 |
| 86 | primary amino compound metabolic process (GO:1901160) | 2.63220259 |
| 87 | I-kappaB phosphorylation (GO:0007252) | 2.62897647 |
| 88 | protein targeting to lysosome (GO:0006622) | 2.62581492 |
| 89 | establishment of protein localization to vacuole (GO:0072666) | 2.62581492 |
| 90 | protein targeting to vacuole (GO:0006623) | 2.62581492 |
| 91 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.62115963 |
| 92 | regulation of hippo signaling (GO:0035330) | 2.60918606 |
| 93 | B cell proliferation (GO:0042100) | 2.59452551 |
| 94 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.59184623 |
| 95 | protein K63-linked deubiquitination (GO:0070536) | 2.58556806 |
| 96 | regulation of B cell apoptotic process (GO:0002902) | 2.57371300 |
| 97 | negative regulation of growth of symbiont in host (GO:0044130) | 2.56173965 |
| 98 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 2.56173965 |
| 99 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 2.56173965 |
| 100 | regulation of growth of symbiont in host (GO:0044126) | 2.56173965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.83847540 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.09325283 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.00644917 |
| 4 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.95446862 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.88743159 |
| 6 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.58036586 |
| 7 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.55408047 |
| 8 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.52915073 |
| 9 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.41840201 |
| 10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.33313443 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.14128623 |
| 12 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.08840218 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.02164258 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.95888745 |
| 15 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.95615996 |
| 16 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.88581616 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.87173791 |
| 18 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.83532675 |
| 19 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.81311895 |
| 20 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.77381160 |
| 21 | GATA1_22025678_ChIP-Seq_K562_Human | 1.77327706 |
| 22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.72153017 |
| 23 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.66425989 |
| 24 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.64952489 |
| 25 | MYB_26560356_Chip-Seq_TH2_Human | 1.64282601 |
| 26 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.63850927 |
| 27 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.61003584 |
| 28 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.60698898 |
| 29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.59848653 |
| 30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.59448689 |
| 31 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.59290576 |
| 32 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.59144410 |
| 33 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.57613233 |
| 34 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.56970089 |
| 35 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.55676744 |
| 36 | STAT3_23295773_ChIP-Seq_U87_Human | 1.48192561 |
| 37 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.45627886 |
| 38 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.44007999 |
| 39 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.43924142 |
| 40 | TCF4_23295773_ChIP-Seq_U87_Human | 1.43480695 |
| 41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.41507027 |
| 42 | TP53_16413492_ChIP-PET_HCT116_Human | 1.40287861 |
| 43 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.40143976 |
| 44 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40143976 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.40105780 |
| 46 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.39968789 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.38156696 |
| 48 | GATA3_26560356_Chip-Seq_TH2_Human | 1.36927652 |
| 49 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.35947992 |
| 50 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.33366110 |
| 51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.31388501 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29662280 |
| 53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.25947378 |
| 54 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25602814 |
| 55 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.21736474 |
| 56 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20344912 |
| 57 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.19053168 |
| 58 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.17465750 |
| 59 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.15218806 |
| 60 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.14891367 |
| 61 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.14172304 |
| 62 | MYB_26560356_Chip-Seq_TH1_Human | 1.13872776 |
| 63 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11466583 |
| 64 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.10277645 |
| 65 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09148295 |
| 66 | GATA3_26560356_Chip-Seq_TH1_Human | 1.07908940 |
| 67 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.07815071 |
| 68 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.07281332 |
| 69 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.07202619 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06600182 |
| 71 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.06502958 |
| 72 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.05961327 |
| 73 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04591944 |
| 74 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.04063266 |
| 75 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.02721108 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.02721108 |
| 77 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02636785 |
| 78 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.01255680 |
| 79 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00905423 |
| 80 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.99989981 |
| 81 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.99861157 |
| 82 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.99391367 |
| 83 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.99162386 |
| 84 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.97861328 |
| 85 | RXR_22108803_ChIP-Seq_LS180_Human | 0.97835760 |
| 86 | MYC_22102868_ChIP-Seq_BL_Human | 0.97734939 |
| 87 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.93350771 |
| 88 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.93187739 |
| 89 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.92932884 |
| 90 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.92259892 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.92161535 |
| 92 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.91660795 |
| 93 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.90974551 |
| 94 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.90895766 |
| 95 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.90822654 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.90705292 |
| 97 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.90703426 |
| 98 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.90595115 |
| 99 | KDM2B_26808549_Chip-Seq_REH_Human | 0.89893172 |
| 100 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.89814743 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 4.67883476 |
| 2 | MP0003787_abnormal_imprinting | 3.59069216 |
| 3 | MP0008057_abnormal_DNA_replication | 3.56441408 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.09708093 |
| 5 | MP0003172_abnormal_lysosome_physiology | 3.02774524 |
| 6 | MP0001800_abnormal_humoral_immune | 2.75207208 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.67103341 |
| 8 | MP0003195_calcinosis | 2.63936684 |
| 9 | MP0008961_abnormal_basal_metabolism | 2.28288473 |
| 10 | MP0001790_abnormal_immune_system | 2.20681619 |
| 11 | MP0005387_immune_system_phenotype | 2.20681619 |
| 12 | MP0003763_abnormal_thymus_physiology | 2.08060413 |
| 13 | MP0005310_abnormal_salivary_gland | 2.00353605 |
| 14 | MP0002822_catalepsy | 1.99823462 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.98799187 |
| 16 | MP0005174_abnormal_tail_pigmentation | 1.98109728 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.97131698 |
| 18 | MP0002009_preneoplasia | 1.85637348 |
| 19 | MP0002452_abnormal_antigen_presenting | 1.79866574 |
| 20 | MP0003183_abnormal_peptide_metabolism | 1.76776395 |
| 21 | MP0002420_abnormal_adaptive_immunity | 1.76312957 |
| 22 | MP0003646_muscle_fatigue | 1.71659740 |
| 23 | MP0002723_abnormal_immune_serum | 1.68376494 |
| 24 | MP0001819_abnormal_immune_cell | 1.68081542 |
| 25 | MP0004036_abnormal_muscle_relaxation | 1.67076469 |
| 26 | MP0005671_abnormal_response_to | 1.65674060 |
| 27 | MP0001835_abnormal_antigen_presentation | 1.64356305 |
| 28 | MP0004145_abnormal_muscle_electrophysio | 1.62674301 |
| 29 | MP0005076_abnormal_cell_differentiation | 1.62156803 |
| 30 | MP0000689_abnormal_spleen_morphology | 1.50059785 |
| 31 | MP0004084_abnormal_cardiac_muscle | 1.47513936 |
| 32 | MP0005266_abnormal_metabolism | 1.44182255 |
| 33 | MP0004130_abnormal_muscle_cell | 1.41345021 |
| 34 | MP0002396_abnormal_hematopoietic_system | 1.35485683 |
| 35 | MP0009384_cardiac_valve_regurgitation | 1.33730794 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.33708300 |
| 37 | MP0002398_abnormal_bone_marrow | 1.33105417 |
| 38 | MP0000015_abnormal_ear_pigmentation | 1.32830355 |
| 39 | MP0003123_paternal_imprinting | 1.30501251 |
| 40 | MP0006138_congestive_heart_failure | 1.29089197 |
| 41 | MP0000716_abnormal_immune_system | 1.28575128 |
| 42 | MP0003690_abnormal_glial_cell | 1.28332692 |
| 43 | MP0002332_abnormal_exercise_endurance | 1.28196214 |
| 44 | MP0003121_genomic_imprinting | 1.22535366 |
| 45 | MP0005167_abnormal_blood-brain_barrier | 1.21934612 |
| 46 | MP0003045_fibrosis | 1.21389893 |
| 47 | MP0005451_abnormal_body_composition | 1.20748192 |
| 48 | MP0000383_abnormal_hair_follicle | 1.16788726 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.16443426 |
| 50 | MP0004381_abnormal_hair_follicle | 1.15804503 |
| 51 | MP0003303_peritoneal_inflammation | 1.14197336 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.08942413 |
| 53 | MP0005535_abnormal_body_temperature | 1.06639927 |
| 54 | MP0003890_abnormal_embryonic-extraembry | 1.05730333 |
| 55 | MP0002229_neurodegeneration | 1.04489950 |
| 56 | MP0002419_abnormal_innate_immunity | 1.01826706 |
| 57 | MP0003950_abnormal_plasma_membrane | 1.01480671 |
| 58 | MP0005025_abnormal_response_to | 1.01015283 |
| 59 | MP0000372_irregular_coat_pigmentation | 0.99135509 |
| 60 | MP0006292_abnormal_olfactory_placode | 0.98382399 |
| 61 | MP0000462_abnormal_digestive_system | 0.98052011 |
| 62 | MP0009046_muscle_twitch | 0.97123310 |
| 63 | MP0001486_abnormal_startle_reflex | 0.95436248 |
| 64 | MP0002234_abnormal_pharynx_morphology | 0.92488052 |
| 65 | MP0002067_abnormal_sensory_capabilities | 0.90406262 |
| 66 | MP0008995_early_reproductive_senescence | 0.89389641 |
| 67 | MP0002429_abnormal_blood_cell | 0.88812578 |
| 68 | MP0002933_joint_inflammation | 0.88383165 |
| 69 | MP0002722_abnormal_immune_system | 0.87814864 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.87618896 |
| 71 | MP0003866_abnormal_defecation | 0.86398182 |
| 72 | MP0002928_abnormal_bile_duct | 0.85707190 |
| 73 | MP0002405_respiratory_system_inflammati | 0.84000293 |
| 74 | MP0002876_abnormal_thyroid_physiology | 0.83667856 |
| 75 | MP0002736_abnormal_nociception_after | 0.83541596 |
| 76 | MP0009745_abnormal_behavioral_response | 0.83404052 |
| 77 | MP0005448_abnormal_energy_balance | 0.82485046 |
| 78 | MP0008058_abnormal_DNA_repair | 0.80717184 |
| 79 | MP0009780_abnormal_chondrocyte_physiolo | 0.80226634 |
| 80 | MP0001845_abnormal_inflammatory_respons | 0.79720564 |
| 81 | MP0005253_abnormal_eye_physiology | 0.79396737 |
| 82 | MP0003283_abnormal_digestive_organ | 0.79331398 |
| 83 | MP0010386_abnormal_urinary_bladder | 0.75552719 |
| 84 | MP0002638_abnormal_pupillary_reflex | 0.75442682 |
| 85 | MP0001502_abnormal_circadian_rhythm | 0.75338917 |
| 86 | MP0001764_abnormal_homeostasis | 0.73659437 |
| 87 | MP0002693_abnormal_pancreas_physiology | 0.72572260 |
| 88 | MP0002078_abnormal_glucose_homeostasis | 0.70796930 |
| 89 | MP0002064_seizures | 0.70756233 |
| 90 | MP0000685_abnormal_immune_system | 0.70656731 |
| 91 | MP0001299_abnormal_eye_distance/ | 0.69156056 |
| 92 | MP0004043_abnormal_pH_regulation | 0.68897652 |
| 93 | MP0002148_abnormal_hypersensitivity_rea | 0.68280425 |
| 94 | MP0001986_abnormal_taste_sensitivity | 0.67423283 |
| 95 | MP0004808_abnormal_hematopoietic_stem | 0.65953087 |
| 96 | MP0001929_abnormal_gametogenesis | 0.65654678 |
| 97 | MP0009785_altered_susceptibility_to | 0.65565058 |
| 98 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.64898670 |
| 99 | MP0002272_abnormal_nervous_system | 0.62909352 |
| 100 | MP0008872_abnormal_physiological_respon | 0.62023367 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Agammaglobulinemia (HP:0004432) | 6.67103358 |
| 2 | Congenital stationary night blindness (HP:0007642) | 4.79926276 |
| 3 | Absent/shortened dynein arms (HP:0200106) | 4.72688458 |
| 4 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.72688458 |
| 5 | Panhypogammaglobulinemia (HP:0003139) | 4.30104973 |
| 6 | Genetic anticipation (HP:0003743) | 4.23331407 |
| 7 | Protruding tongue (HP:0010808) | 4.03843823 |
| 8 | Chronic hepatic failure (HP:0100626) | 3.82138361 |
| 9 | Recurrent bacterial skin infections (HP:0005406) | 3.76370134 |
| 10 | Clumsiness (HP:0002312) | 3.60201635 |
| 11 | Recurrent bronchitis (HP:0002837) | 3.58482720 |
| 12 | Cellulitis (HP:0100658) | 3.57971197 |
| 13 | Pigmentary retinal degeneration (HP:0001146) | 3.53559190 |
| 14 | Fair hair (HP:0002286) | 3.40298012 |
| 15 | Meningitis (HP:0001287) | 3.30099212 |
| 16 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.29495810 |
| 17 | Hyperventilation (HP:0002883) | 3.28074179 |
| 18 | Recurrent pneumonia (HP:0006532) | 3.27459441 |
| 19 | Renal cortical cysts (HP:0000803) | 3.20387634 |
| 20 | Birth length less than 3rd percentile (HP:0003561) | 3.18558371 |
| 21 | Recurrent sinusitis (HP:0011108) | 3.11202073 |
| 22 | Nephronophthisis (HP:0000090) | 3.10554460 |
| 23 | Viral hepatitis (HP:0006562) | 3.02762175 |
| 24 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.96640278 |
| 25 | Recurrent abscess formation (HP:0002722) | 2.87174761 |
| 26 | Progressive cerebellar ataxia (HP:0002073) | 2.85043652 |
| 27 | Abnormality of the renal medulla (HP:0100957) | 2.76498540 |
| 28 | Eczematoid dermatitis (HP:0000976) | 2.75987047 |
| 29 | Osteomyelitis (HP:0002754) | 2.72380942 |
| 30 | Increased cerebral lipofuscin (HP:0011813) | 2.70496317 |
| 31 | Generalized hypopigmentation of hair (HP:0011358) | 2.68424807 |
| 32 | Chronic otitis media (HP:0000389) | 2.64032002 |
| 33 | Molar tooth sign on MRI (HP:0002419) | 2.63125132 |
| 34 | Abnormality of midbrain morphology (HP:0002418) | 2.63125132 |
| 35 | Agitation (HP:0000713) | 2.61770933 |
| 36 | Limb hypertonia (HP:0002509) | 2.58216008 |
| 37 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.55264880 |
| 38 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.55264880 |
| 39 | Abnormality of the prostate (HP:0008775) | 2.51054180 |
| 40 | Chronic sinusitis (HP:0011109) | 2.50016169 |
| 41 | Pancreatic cysts (HP:0001737) | 2.45531366 |
| 42 | Infantile muscular hypotonia (HP:0008947) | 2.44853025 |
| 43 | Abnormality of the renal cortex (HP:0011035) | 2.44535623 |
| 44 | Broad face (HP:0000283) | 2.43330201 |
| 45 | Widely spaced teeth (HP:0000687) | 2.38801814 |
| 46 | Chorioretinal atrophy (HP:0000533) | 2.37985279 |
| 47 | Dialeptic seizures (HP:0011146) | 2.37798095 |
| 48 | Hemiplegia (HP:0002301) | 2.37143734 |
| 49 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.36979662 |
| 50 | Recurrent lower respiratory tract infections (HP:0002783) | 2.36316225 |
| 51 | Recurrent viral infections (HP:0004429) | 2.35020468 |
| 52 | Eosinophilia (HP:0001880) | 2.32418774 |
| 53 | Colitis (HP:0002583) | 2.31643603 |
| 54 | Truncal obesity (HP:0001956) | 2.31065181 |
| 55 | Papilloma (HP:0012740) | 2.27974159 |
| 56 | Verrucae (HP:0200043) | 2.27974159 |
| 57 | Recurrent fungal infections (HP:0002841) | 2.26568927 |
| 58 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.25639115 |
| 59 | Mediastinal lymphadenopathy (HP:0100721) | 2.25361572 |
| 60 | Absence seizures (HP:0002121) | 2.24083240 |
| 61 | Pancreatic fibrosis (HP:0100732) | 2.22098946 |
| 62 | Posterior subcapsular cataract (HP:0007787) | 2.18921207 |
| 63 | Macular degeneration (HP:0000608) | 2.13935972 |
| 64 | Encephalitis (HP:0002383) | 2.12143005 |
| 65 | Sepsis (HP:0100806) | 2.08612991 |
| 66 | Inflammation of the large intestine (HP:0002037) | 2.06790386 |
| 67 | Gastrointestinal stroma tumor (HP:0100723) | 2.06120424 |
| 68 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.01555684 |
| 69 | Atonic seizures (HP:0010819) | 2.01167467 |
| 70 | Abnormality of eosinophils (HP:0001879) | 2.00436307 |
| 71 | Recurrent skin infections (HP:0001581) | 1.99207082 |
| 72 | Thoracolumbar scoliosis (HP:0002944) | 1.97004020 |
| 73 | Mucopolysacchariduria (HP:0008155) | 1.95083911 |
| 74 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.95083911 |
| 75 | Gastrointestinal inflammation (HP:0004386) | 1.93770816 |
| 76 | True hermaphroditism (HP:0010459) | 1.92810343 |
| 77 | Cervical subluxation (HP:0003308) | 1.90159172 |
| 78 | Abnormal ciliary motility (HP:0012262) | 1.88907375 |
| 79 | Partial agenesis of the corpus callosum (HP:0001338) | 1.88590222 |
| 80 | Gaze-evoked nystagmus (HP:0000640) | 1.88426948 |
| 81 | Neurodegeneration (HP:0002180) | 1.87043042 |
| 82 | Calf muscle hypertrophy (HP:0008981) | 1.85234787 |
| 83 | IgA deficiency (HP:0002720) | 1.83764347 |
| 84 | Relative macrocephaly (HP:0004482) | 1.83712647 |
| 85 | Thrombocytosis (HP:0001894) | 1.82836972 |
| 86 | Stomach cancer (HP:0012126) | 1.82832967 |
| 87 | Flared iliac wings (HP:0002869) | 1.82189466 |
| 88 | Restrictive lung disease (HP:0002091) | 1.79700464 |
| 89 | Broad-based gait (HP:0002136) | 1.79678664 |
| 90 | Granulocytopenia (HP:0001913) | 1.77250721 |
| 91 | Hypoplastic labia majora (HP:0000059) | 1.76863077 |
| 92 | Obstructive lung disease (HP:0006536) | 1.72685679 |
| 93 | Chronic obstructive pulmonary disease (HP:0006510) | 1.72685679 |
| 94 | Bronchitis (HP:0012387) | 1.71791320 |
| 95 | Oligodactyly (hands) (HP:0001180) | 1.71209977 |
| 96 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.70073935 |
| 97 | Abnormality of the labia majora (HP:0012881) | 1.69596760 |
| 98 | Global brain atrophy (HP:0002283) | 1.67761348 |
| 99 | Hematochezia (HP:0002573) | 1.64780162 |
| 100 | Ulnar claw (HP:0001178) | 1.64458720 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ACVR1B | 4.23848584 |
| 2 | FRK | 3.18435075 |
| 3 | CAMKK2 | 3.06139551 |
| 4 | BMPR1B | 2.94208143 |
| 5 | TEC | 2.87782943 |
| 6 | BTK | 2.50024938 |
| 7 | ITK | 2.38329119 |
| 8 | IRAK4 | 2.24497251 |
| 9 | TLK1 | 2.07216532 |
| 10 | TNIK | 2.06482178 |
| 11 | TNK2 | 2.04297789 |
| 12 | INSRR | 1.88603747 |
| 13 | SYK | 1.82908545 |
| 14 | BMPR2 | 1.76752811 |
| 15 | CDK12 | 1.71935002 |
| 16 | NUAK1 | 1.70542000 |
| 17 | OBSCN | 1.64278149 |
| 18 | IRAK1 | 1.61255101 |
| 19 | BLK | 1.48997907 |
| 20 | MAPK13 | 1.42918869 |
| 21 | MAP3K2 | 1.42017996 |
| 22 | STK16 | 1.40973635 |
| 23 | NTRK3 | 1.35703184 |
| 24 | PBK | 1.28327053 |
| 25 | LYN | 1.28205415 |
| 26 | PKN1 | 1.27680645 |
| 27 | EIF2AK3 | 1.26490721 |
| 28 | PTK2B | 1.25382404 |
| 29 | BRSK2 | 1.24228733 |
| 30 | GRK6 | 1.23734371 |
| 31 | MAPKAPK3 | 1.21210116 |
| 32 | DAPK2 | 1.19870026 |
| 33 | ZAK | 1.18035789 |
| 34 | IKBKB | 1.18014674 |
| 35 | TGFBR1 | 1.17668078 |
| 36 | CCNB1 | 1.17649665 |
| 37 | TAOK3 | 1.15947342 |
| 38 | LCK | 1.14072291 |
| 39 | KIT | 1.12041129 |
| 40 | STK38 | 1.10210958 |
| 41 | CHUK | 1.04206883 |
| 42 | CDK3 | 1.00453531 |
| 43 | PIM1 | 1.00119735 |
| 44 | MARK2 | 0.99974453 |
| 45 | CAMK1D | 0.96448023 |
| 46 | MAP2K1 | 0.93426964 |
| 47 | RIPK4 | 0.90887113 |
| 48 | ZAP70 | 0.90431885 |
| 49 | CAMKK1 | 0.84921987 |
| 50 | MAPK11 | 0.83981613 |
| 51 | LATS1 | 0.83476892 |
| 52 | TYK2 | 0.81098709 |
| 53 | NTRK2 | 0.80881203 |
| 54 | MAP4K1 | 0.78203160 |
| 55 | ADRBK1 | 0.77035588 |
| 56 | WNK3 | 0.76719978 |
| 57 | PIK3CG | 0.75879218 |
| 58 | PRKCQ | 0.74927747 |
| 59 | ADRBK2 | 0.74843741 |
| 60 | MAPK12 | 0.73515218 |
| 61 | MAPK15 | 0.72609672 |
| 62 | PIK3CA | 0.71627948 |
| 63 | TXK | 0.70787816 |
| 64 | MAP3K13 | 0.69728932 |
| 65 | SIK2 | 0.69511526 |
| 66 | JAK1 | 0.67933587 |
| 67 | IKBKE | 0.65228116 |
| 68 | RPS6KB2 | 0.64796782 |
| 69 | HIPK2 | 0.61845773 |
| 70 | MAP3K4 | 0.60877489 |
| 71 | TRPM7 | 0.58874675 |
| 72 | FES | 0.58676523 |
| 73 | CAMK1 | 0.57951154 |
| 74 | PRKAA1 | 0.55046435 |
| 75 | PAK3 | 0.54375702 |
| 76 | MAP3K7 | 0.53525961 |
| 77 | MELK | 0.53276625 |
| 78 | SGK2 | 0.52989161 |
| 79 | PASK | 0.52840732 |
| 80 | FGFR2 | 0.51584794 |
| 81 | TIE1 | 0.51337490 |
| 82 | PRKAA2 | 0.51131158 |
| 83 | ICK | 0.51078593 |
| 84 | PHKG2 | 0.50569557 |
| 85 | PHKG1 | 0.50569557 |
| 86 | IRAK2 | 0.49746617 |
| 87 | JAK2 | 0.48577481 |
| 88 | JAK3 | 0.48140501 |
| 89 | CSNK1D | 0.45096439 |
| 90 | RPS6KA3 | 0.45084927 |
| 91 | AKT3 | 0.43596518 |
| 92 | HCK | 0.42746598 |
| 93 | RPS6KA5 | 0.42597969 |
| 94 | CASK | 0.41756277 |
| 95 | NEK9 | 0.41555830 |
| 96 | PRKCZ | 0.39858762 |
| 97 | SGK223 | 0.38883353 |
| 98 | SGK494 | 0.38883353 |
| 99 | DMPK | 0.38180735 |
| 100 | CAMK4 | 0.37722490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.55153927 |
| 2 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.42068247 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.31796341 |
| 4 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 3.12697987 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.53782112 |
| 6 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.47229530 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.45730811 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.44516456 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.32534729 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 2.25489466 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.12450697 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.03006816 |
| 13 | Olfactory transduction_Homo sapiens_hsa04740 | 1.98004851 |
| 14 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.91193607 |
| 15 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.89645468 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.67080189 |
| 17 | ABC transporters_Homo sapiens_hsa02010 | 1.64763080 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.57523173 |
| 19 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.56409468 |
| 20 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.46832608 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.43260429 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.38726740 |
| 23 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.35987460 |
| 24 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.33785154 |
| 25 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.24086089 |
| 26 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.24025749 |
| 27 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.15320301 |
| 28 | Lysine degradation_Homo sapiens_hsa00310 | 1.13699260 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.12313214 |
| 30 | Taste transduction_Homo sapiens_hsa04742 | 1.08350680 |
| 31 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.05581875 |
| 32 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.05421251 |
| 33 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.03756937 |
| 34 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.02634389 |
| 35 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.01477071 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.99074698 |
| 37 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.95582397 |
| 38 | RNA polymerase_Homo sapiens_hsa03020 | 0.93094681 |
| 39 | Homologous recombination_Homo sapiens_hsa03440 | 0.92939002 |
| 40 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.91469316 |
| 41 | Tuberculosis_Homo sapiens_hsa05152 | 0.91187169 |
| 42 | Nicotine addiction_Homo sapiens_hsa05033 | 0.87339085 |
| 43 | Circadian rhythm_Homo sapiens_hsa04710 | 0.87329358 |
| 44 | Morphine addiction_Homo sapiens_hsa05032 | 0.86794765 |
| 45 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.85200644 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.84371389 |
| 47 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.83017413 |
| 48 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.82306086 |
| 49 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.78745405 |
| 50 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.78348368 |
| 51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.77781164 |
| 52 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.76875007 |
| 53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.76750129 |
| 54 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.76578846 |
| 55 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76104322 |
| 56 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.73696984 |
| 57 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.73002057 |
| 58 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71230342 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.67533470 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.64955349 |
| 61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.64054316 |
| 62 | RNA degradation_Homo sapiens_hsa03018 | 0.63342667 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.62169615 |
| 64 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.61545361 |
| 65 | Platelet activation_Homo sapiens_hsa04611 | 0.60450401 |
| 66 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.59766206 |
| 67 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.58239379 |
| 68 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.56871069 |
| 69 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.56865292 |
| 70 | Viral myocarditis_Homo sapiens_hsa05416 | 0.55962799 |
| 71 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.54725060 |
| 72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.53983747 |
| 73 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.53890320 |
| 74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53564811 |
| 75 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.53537140 |
| 76 | Measles_Homo sapiens_hsa05162 | 0.52322916 |
| 77 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.50596795 |
| 78 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.47532771 |
| 79 | Salivary secretion_Homo sapiens_hsa04970 | 0.46254478 |
| 80 | Insulin secretion_Homo sapiens_hsa04911 | 0.44745756 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44669636 |
| 82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.44451575 |
| 83 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.41476417 |
| 84 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.41066245 |
| 85 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.41016598 |
| 86 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.40911484 |
| 87 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.39941957 |
| 88 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.39365631 |
| 89 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.38701559 |
| 90 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.38456778 |
| 91 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.38086575 |
| 92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37432559 |
| 93 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.37061893 |
| 94 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.36088326 |
| 95 | Insulin resistance_Homo sapiens_hsa04931 | 0.36052561 |
| 96 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.35774678 |
| 97 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.35460447 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.34032045 |
| 99 | Long-term depression_Homo sapiens_hsa04730 | 0.29833829 |
| 100 | Influenza A_Homo sapiens_hsa05164 | 0.29497480 |

