CCP110

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)9.99816448
2axon ensheathment in central nervous system (GO:0032291)9.99816448
3axon ensheathment (GO:0008366)6.09944954
4ensheathment of neurons (GO:0007272)6.09944954
5myelination (GO:0042552)6.06564260
6fatty acid elongation (GO:0030497)5.10603140
7long-chain fatty acid biosynthetic process (GO:0042759)4.76303891
8negative regulation of neurotransmitter secretion (GO:0046929)4.70178092
9myelin maintenance (GO:0043217)4.57011324
10asymmetric protein localization (GO:0008105)4.40929897
11pyrimidine nucleobase catabolic process (GO:0006208)4.40058751
12apical protein localization (GO:0045176)4.30873797
13negative regulation of neurotransmitter transport (GO:0051589)4.30371546
14establishment of mitochondrion localization (GO:0051654)4.28291160
15oligodendrocyte differentiation (GO:0048709)4.16516155
16L-amino acid import (GO:0043092)3.94351503
17presynaptic membrane organization (GO:0097090)3.94095947
18astrocyte development (GO:0014002)3.88980769
19postsynaptic membrane organization (GO:0001941)3.87488014
20microtubule depolymerization (GO:0007019)3.78741975
21eye photoreceptor cell differentiation (GO:0001754)3.73318318
22photoreceptor cell differentiation (GO:0046530)3.73318318
23presynaptic membrane assembly (GO:0097105)3.66658756
24transmission of nerve impulse (GO:0019226)3.65302068
25neuron cell-cell adhesion (GO:0007158)3.63843302
26adult walking behavior (GO:0007628)3.62137089
27negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.58713629
28gamma-aminobutyric acid transport (GO:0015812)3.58126701
29glycerophospholipid catabolic process (GO:0046475)3.57284924
30regulation of collateral sprouting (GO:0048670)3.55099061
31peptidyl-tyrosine autophosphorylation (GO:0038083)3.54896715
32negative regulation of inclusion body assembly (GO:0090084)3.53195194
33protein polyglutamylation (GO:0018095)3.52179897
34piRNA metabolic process (GO:0034587)3.51970705
35cilium or flagellum-dependent cell motility (GO:0001539)3.47854501
36positive regulation of oligodendrocyte differentiation (GO:0048714)3.46996984
37nucleobase catabolic process (GO:0046113)3.46227944
38intraciliary transport (GO:0042073)3.42211363
39vocalization behavior (GO:0071625)3.39578403
40peripheral nervous system axon ensheathment (GO:0032292)3.39047622
41myelination in peripheral nervous system (GO:0022011)3.39047622
42microtubule polymerization or depolymerization (GO:0031109)3.38593791
43limb bud formation (GO:0060174)3.33379568
44axoneme assembly (GO:0035082)3.29555107
45neuronal ion channel clustering (GO:0045161)3.28434904
46cerebral cortex radially oriented cell migration (GO:0021799)3.28284890
47negative regulation of protein localization to cell surface (GO:2000009)3.25171344
48neural tube formation (GO:0001841)3.22922105
49cilium organization (GO:0044782)3.18252589
50histone H2A acetylation (GO:0043968)3.16738187
51regulation of short-term neuronal synaptic plasticity (GO:0048172)3.15962868
52regulation of DNA endoreduplication (GO:0032875)3.15952430
53protein localization to synapse (GO:0035418)3.15386145
54neuronal action potential propagation (GO:0019227)3.14335227
55cilium assembly (GO:0042384)3.13419267
56import into cell (GO:0098657)3.05002212
57nonmotile primary cilium assembly (GO:0035058)3.04838904
58ionotropic glutamate receptor signaling pathway (GO:0035235)3.04555399
59negative regulation of axonogenesis (GO:0050771)3.04280350
60cerebellar granule cell differentiation (GO:0021707)3.01253458
61regulation of cilium movement (GO:0003352)3.01192098
62substantia nigra development (GO:0021762)2.97943437
63synaptic transmission, glutamatergic (GO:0035249)2.96232657
64protein localization to cilium (GO:0061512)2.95966567
65DNA double-strand break processing (GO:0000729)2.95645272
66membrane tubulation (GO:0097320)2.93522961
67motile cilium assembly (GO:0044458)2.93097993
68startle response (GO:0001964)2.91132946
69amino acid import (GO:0043090)2.89229859
70creatine metabolic process (GO:0006600)2.88493314
71lateral sprouting from an epithelium (GO:0060601)2.86984831
72DNA methylation involved in gamete generation (GO:0043046)2.85962176
73negative regulation of synaptic transmission, GABAergic (GO:0032229)2.85047815
74Golgi to endosome transport (GO:0006895)2.84410240
75protein palmitoylation (GO:0018345)2.84019086
76neuron recognition (GO:0008038)2.80959370
77neurotransmitter-gated ion channel clustering (GO:0072578)2.76724250
78response to methylmercury (GO:0051597)2.75799613
79axonal fasciculation (GO:0007413)2.73093663
80positive regulation of action potential (GO:0045760)2.72847560
81nerve growth factor signaling pathway (GO:0038180)2.72551143
82synaptic vesicle maturation (GO:0016188)2.72028195
83acrosome reaction (GO:0007340)2.71697285
84mitochondrion transport along microtubule (GO:0047497)2.71087992
85establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.71087992
86glutamate receptor signaling pathway (GO:0007215)2.71012895
87monoubiquitinated protein deubiquitination (GO:0035520)2.69538038
88male meiosis (GO:0007140)2.68284889
89positive regulation of mitochondrial fission (GO:0090141)2.67056549
90regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.66455376
91substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.66326468
92substrate-independent telencephalic tangential migration (GO:0021826)2.66326468
93microtubule-based movement (GO:0007018)2.66178777
94dendritic spine morphogenesis (GO:0060997)2.65696757
95synaptic vesicle exocytosis (GO:0016079)2.64838827
96negative regulation of JUN kinase activity (GO:0043508)2.64699194
97negative regulation of DNA recombination (GO:0045910)2.62605317
98behavioral response to nicotine (GO:0035095)2.62092329
99microtubule severing (GO:0051013)2.61661674
100positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.61462282
101Leydig cell differentiation (GO:0033327)2.61227073
102negative regulation of axon extension (GO:0030517)2.60473548
103organ growth (GO:0035265)2.60404423
104neuron-neuron synaptic transmission (GO:0007270)2.60147203
105microtubule bundle formation (GO:0001578)2.59188972
106fusion of sperm to egg plasma membrane (GO:0007342)2.59148355
107negative regulation of macroautophagy (GO:0016242)2.58725650
108negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.58252356
109axonemal dynein complex assembly (GO:0070286)2.57814488
110cilium morphogenesis (GO:0060271)2.57561414
111positive regulation of dendritic spine morphogenesis (GO:0061003)2.57423938
112synapse assembly (GO:0007416)2.56575161
113protein localization to endosome (GO:0036010)2.55891671
114neurofilament cytoskeleton organization (GO:0060052)2.55538755
115membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.55315414
116regulation of synaptic transmission, glutamatergic (GO:0051966)2.55306620
117G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.54496159
118epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.54402729
119dendrite morphogenesis (GO:0048813)2.54151850
120magnesium ion transport (GO:0015693)2.52841929
121microtubule nucleation (GO:0007020)2.52296187
122regulation of feeding behavior (GO:0060259)2.51203630
123response to redox state (GO:0051775)2.50882982
124regulation of synaptic vesicle exocytosis (GO:2000300)2.50683518
125negative regulation of organelle assembly (GO:1902116)2.50234005
126C4-dicarboxylate transport (GO:0015740)2.50148149
127mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.49411048
128cellular component assembly involved in morphogenesis (GO:0010927)2.49386605
129resolution of meiotic recombination intermediates (GO:0000712)2.48669868
130microtubule anchoring (GO:0034453)2.48068693
131cytoskeleton-dependent intracellular transport (GO:0030705)2.47367695
132regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.46006769
133peripheral nervous system development (GO:0007422)2.45653405
134glycine transport (GO:0015816)2.45610798
135glycosphingolipid biosynthetic process (GO:0006688)2.45600718
136neurotransmitter secretion (GO:0007269)2.45000283
137ventricular system development (GO:0021591)2.44742586
138regulation of nuclear cell cycle DNA replication (GO:0033262)2.44697159
139glutamate secretion (GO:0014047)2.44612643
140auditory behavior (GO:0031223)2.44295806
141regulation of synapse structural plasticity (GO:0051823)2.43823075
142negative regulation of cytosolic calcium ion concentration (GO:0051481)2.43692789
143striatum development (GO:0021756)2.41830081
144positive regulation of synapse assembly (GO:0051965)2.41574987
145epithelial cilium movement (GO:0003351)2.41233792
146glial cell development (GO:0021782)2.40995955
147sperm capacitation (GO:0048240)2.40809727
148mating behavior (GO:0007617)2.40359911
149neurotransmitter uptake (GO:0001504)2.39932842
150cyclic nucleotide catabolic process (GO:0009214)2.39761031
151synaptonemal complex organization (GO:0070193)2.39540278
152regulation of synaptic vesicle transport (GO:1902803)2.39213517
153positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.39121759
154neuron remodeling (GO:0016322)2.38873026
155gamma-aminobutyric acid signaling pathway (GO:0007214)2.38853033
156microtubule-based transport (GO:0010970)2.38690497
157positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.38315063
158mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.38315063
159adult locomotory behavior (GO:0008344)2.38269909
160cilium movement (GO:0003341)2.37932339
161mechanosensory behavior (GO:0007638)2.37846356
162negative regulation of microtubule depolymerization (GO:0007026)2.37603656
163spinal cord motor neuron differentiation (GO:0021522)2.37254631
164positive regulation of neurological system process (GO:0031646)2.37141667
165mRNA splice site selection (GO:0006376)2.36782741
166enteric nervous system development (GO:0048484)2.36433311
167cell migration in hindbrain (GO:0021535)2.35886277
168* centriole replication (GO:0007099)2.35718261
169central nervous system projection neuron axonogenesis (GO:0021952)2.35586777
170regulation of respiratory system process (GO:0044065)2.35306097
171regulation of microtubule depolymerization (GO:0031114)2.34737127

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.27067076
2GBX2_23144817_ChIP-Seq_PC3_Human3.35156660
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.56624448
4* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.31462468
5TAF15_26573619_Chip-Seq_HEK293_Human2.25868689
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.19771542
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.16002160
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.14849065
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.11523788
10RNF2_18974828_ChIP-Seq_MESCs_Mouse1.99064855
11EZH2_18974828_ChIP-Seq_MESCs_Mouse1.99064855
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93569441
13MTF2_20144788_ChIP-Seq_MESCs_Mouse1.88880486
14RNF2_27304074_Chip-Seq_ESCs_Mouse1.88377785
15DROSHA_22980978_ChIP-Seq_HELA_Human1.86248297
16OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.84104162
17SUZ12_27294783_Chip-Seq_ESCs_Mouse1.80912258
18EZH2_27294783_Chip-Seq_ESCs_Mouse1.80735839
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.80117491
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.78972846
21RBPJ_22232070_ChIP-Seq_NCS_Mouse1.76150342
22RARB_27405468_Chip-Seq_BRAIN_Mouse1.76042597
23CBX2_27304074_Chip-Seq_ESCs_Mouse1.75542011
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.75318398
25ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73795889
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.72099557
27REST_21632747_ChIP-Seq_MESCs_Mouse1.71009707
28SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.70941653
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70132390
30RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.69118285
31SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.67113433
32JARID2_20075857_ChIP-Seq_MESCs_Mouse1.66154971
33SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.64617223
34RNF2_27304074_Chip-Seq_NSC_Mouse1.63132610
35E2F7_22180533_ChIP-Seq_HELA_Human1.62462815
36AR_21572438_ChIP-Seq_LNCaP_Human1.61485211
37SMAD3_21741376_ChIP-Seq_EPCs_Human1.60984155
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59073278
39SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58650784
40ER_23166858_ChIP-Seq_MCF-7_Human1.58506010
41GATA1_26923725_Chip-Seq_HPCs_Mouse1.57948049
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.56852663
43STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.54572168
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.52448636
45HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.52262990
46VDR_22108803_ChIP-Seq_LS180_Human1.52117748
47TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52087540
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.52044955
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48669717
50E2F4_17652178_ChIP-ChIP_JURKAT_Human1.48568903
51CTBP2_25329375_ChIP-Seq_LNCAP_Human1.48467219
52FUS_26573619_Chip-Seq_HEK293_Human1.46992707
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45304218
54STAT3_23295773_ChIP-Seq_U87_Human1.43718768
55PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42058268
56FLI1_27457419_Chip-Seq_LIVER_Mouse1.41137497
57CBP_20019798_ChIP-Seq_JUKART_Human1.40421040
58IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.40421040
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.39325241
60NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.38593179
61P53_22127205_ChIP-Seq_FIBROBLAST_Human1.37651415
62SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37260808
63KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.35277701
64REST_18959480_ChIP-ChIP_MESCs_Mouse1.33190980
65AR_25329375_ChIP-Seq_VCAP_Human1.32986075
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.31300672
67LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31117711
68IRF1_19129219_ChIP-ChIP_H3396_Human1.30531762
69TCF4_23295773_ChIP-Seq_U87_Human1.28830476
70PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28368191
71SMAD4_21799915_ChIP-Seq_A2780_Human1.26935408
72MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26017823
73SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.25991486
74CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25555011
75KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25477962
76MYC_18940864_ChIP-ChIP_HL60_Human1.22135696
77PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20558286
78TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20405618
79P300_19829295_ChIP-Seq_ESCs_Human1.19922860
80KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19375449
81RING1B_27294783_Chip-Seq_NPCs_Mouse1.19358880
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19010305
83SOX9_26525672_Chip-Seq_HEART_Mouse1.18426253
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.18083513
85PIAS1_25552417_ChIP-Seq_VCAP_Human1.18071936
86RUNX2_22187159_ChIP-Seq_PCA_Human1.17202161
87GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13823861
88ARNT_22903824_ChIP-Seq_MCF-7_Human1.13507373
89PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13109230
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12527835
91TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12275326
92HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11998146
93AHR_22903824_ChIP-Seq_MCF-7_Human1.11931524
94EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.11795113
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.11519821
96JUN_21703547_ChIP-Seq_K562_Human1.11352025
97RING1B_27294783_Chip-Seq_ESCs_Mouse1.10447085
98CMYC_18555785_Chip-Seq_ESCs_Mouse1.08529344
99CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08506377
100P53_22387025_ChIP-Seq_ESCs_Mouse1.08289436
101TBL1_22424771_ChIP-Seq_293T_Human1.08236013
102ZNF274_21170338_ChIP-Seq_K562_Hela1.07586915
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.06872652
104POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06774256
105BCAT_22108803_ChIP-Seq_LS180_Human1.06469770
106TAL1_26923725_Chip-Seq_HPCs_Mouse1.06397164
107E2F1_18555785_Chip-Seq_ESCs_Mouse1.05557667
108POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05299127
109TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05299127
110LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05094236
111FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.04175784
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03987544
113MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03386270
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.03360992
115FOXM1_23109430_ChIP-Seq_U2OS_Human1.02162687
116EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01073144
117SOX2_21211035_ChIP-Seq_LN229_Gbm1.00985717
118IGF1R_20145208_ChIP-Seq_DFB_Human1.00865207
119PADI4_21655091_ChIP-ChIP_MCF-7_Human0.99598160
120SALL1_21062744_ChIP-ChIP_HESCs_Human0.98005592
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97944695
122P300_18555785_Chip-Seq_ESCs_Mouse0.97444576
123TCF4_22108803_ChIP-Seq_LS180_Human0.97222784
124ELK1_19687146_ChIP-ChIP_HELA_Human0.97114032
125YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95858556
126SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95484719
127TP53_22573176_ChIP-Seq_HFKS_Human0.95441738
128SUZ12_18555785_Chip-Seq_ESCs_Mouse0.95218124
129PRDM14_20953172_ChIP-Seq_ESCs_Human0.94477256
130CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.94447123
131EZH2_27294783_Chip-Seq_NPCs_Mouse0.94425725
132WT1_19549856_ChIP-ChIP_CCG9911_Human0.93436419
133SMAD4_21741376_ChIP-Seq_EPCs_Human0.92619344
134EWS_26573619_Chip-Seq_HEK293_Human0.92550322
135SOX2_16153702_ChIP-ChIP_HESCs_Human0.92033914
136EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.91829992

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination3.93768599
2MP0003880_abnormal_central_pattern3.65121919
3MP0004270_analgesia3.37269916
4MP0005410_abnormal_fertilization3.09176469
5MP0003950_abnormal_plasma_membrane3.01112232
6MP0004859_abnormal_synaptic_plasticity2.86842944
7MP0004885_abnormal_endolymph2.75786311
8MP0001486_abnormal_startle_reflex2.49360007
9MP0000778_abnormal_nervous_system2.48673065
10MP0004742_abnormal_vestibular_system2.45354361
11MP0003136_yellow_coat_color2.40160517
12MP0002272_abnormal_nervous_system2.37895498
13MP0001529_abnormal_vocalization2.31685086
14MP0001485_abnormal_pinna_reflex2.27115544
15MP0003690_abnormal_glial_cell2.16623338
16MP0009046_muscle_twitch2.13853003
17MP0002064_seizures2.13543509
18MP0000569_abnormal_digit_pigmentation2.12132973
19MP0006276_abnormal_autonomic_nervous2.09886776
20MP0003635_abnormal_synaptic_transmissio2.09216052
21MP0008877_abnormal_DNA_methylation2.03276256
22MP0005171_absent_coat_pigmentation1.99397858
23MP0005423_abnormal_somatic_nervous1.98219248
24MP0003634_abnormal_glial_cell1.98076879
25MP0002734_abnormal_mechanical_nocicepti1.90317280
26MP0003329_amyloid_beta_deposits1.84741362
27MP0008058_abnormal_DNA_repair1.76801529
28MP0009745_abnormal_behavioral_response1.76330338
29MP0002229_neurodegeneration1.74731099
30MP0010094_abnormal_chromosome_stability1.73417828
31MP0001188_hyperpigmentation1.69887811
32MP0000955_abnormal_spinal_cord1.66815626
33MP0003890_abnormal_embryonic-extraembry1.65804095
34MP0002882_abnormal_neuron_morphology1.61945030
35MP0004142_abnormal_muscle_tone1.60436592
36MP0005409_darkened_coat_color1.58059133
37MP0003632_abnormal_nervous_system1.57957728
38MP0001905_abnormal_dopamine_level1.57776087
39MP0005551_abnormal_eye_electrophysiolog1.56482811
40MP0002063_abnormal_learning/memory/cond1.55793503
41MP0000566_synostosis1.55337083
42MP0003698_abnormal_male_reproductive1.51600006
43MP0008569_lethality_at_weaning1.46816729
44MP0003937_abnormal_limbs/digits/tail_de1.45928995
45MP0002572_abnormal_emotion/affect_behav1.43626486
46MP0002736_abnormal_nociception_after1.43595773
47MP0002653_abnormal_ependyma_morphology1.43577202
48MP0003122_maternal_imprinting1.42270420
49MP0002752_abnormal_somatic_nervous1.36090183
50MP0002067_abnormal_sensory_capabilities1.34617638
51MP0001299_abnormal_eye_distance/1.34226740
52MP0004134_abnormal_chest_morphology1.33528868
53MP0000462_abnormal_digestive_system1.31915626
54MP0000537_abnormal_urethra_morphology1.31135908
55MP0002638_abnormal_pupillary_reflex1.29088096
56MP0002751_abnormal_autonomic_nervous1.29026699
57MP0000383_abnormal_hair_follicle1.28927742
58MP0003938_abnormal_ear_development1.28261575
59MP0001346_abnormal_lacrimal_gland1.27628904
60MP0002184_abnormal_innervation1.27032866
61MP0008995_early_reproductive_senescence1.26607053
62MP0001984_abnormal_olfaction1.26194152
63MP0001963_abnormal_hearing_physiology1.26072133
64MP0002152_abnormal_brain_morphology1.25643314
65MP0004924_abnormal_behavior1.25596828
66MP0005386_behavior/neurological_phenoty1.25596828
67MP0010678_abnormal_skin_adnexa1.24250828
68MP0002066_abnormal_motor_capabilities/c1.23900766
69MP0006072_abnormal_retinal_apoptosis1.22647262
70MP0001440_abnormal_grooming_behavior1.21839886
71MP0001929_abnormal_gametogenesis1.21087820
72MP0005623_abnormal_meninges_morphology1.20119591
73MP0003861_abnormal_nervous_system1.18598687
74MP0002234_abnormal_pharynx_morphology1.17836660
75MP0001970_abnormal_pain_threshold1.17707973
76MP0003631_nervous_system_phenotype1.16844940
77MP0008057_abnormal_DNA_replication1.14911281
78MP0005187_abnormal_penis_morphology1.14476798
79MP0000631_abnormal_neuroendocrine_gland1.10269078
80MP0002733_abnormal_thermal_nociception1.10156591
81MP0004043_abnormal_pH_regulation1.10083042
82MP0005645_abnormal_hypothalamus_physiol1.05768316
83MP0004811_abnormal_neuron_physiology1.03747221
84MP0003787_abnormal_imprinting1.03238409
85MP0005195_abnormal_posterior_eye1.02754127
86MP0005253_abnormal_eye_physiology1.00783211
87MP0001968_abnormal_touch/_nociception0.99815298
88MP0004145_abnormal_muscle_electrophysio0.99722077
89MP0002557_abnormal_social/conspecific_i0.98331656
90MP0002210_abnormal_sex_determination0.98120212
91MP0005646_abnormal_pituitary_gland0.97035398
92MP0001177_atelectasis0.97034056
93MP0001293_anophthalmia0.96868198
94MP0006292_abnormal_olfactory_placode0.96376494
95MP0000026_abnormal_inner_ear0.95067603
96MP0003718_maternal_effect0.93938073
97MP0005499_abnormal_olfactory_system0.93848360
98MP0005394_taste/olfaction_phenotype0.93848360
99MP0003633_abnormal_nervous_system0.93626281
100MP0002160_abnormal_reproductive_system0.90145839
101MP0004133_heterotaxia0.89253985
102MP0002735_abnormal_chemical_nociception0.87768221
103MP0001986_abnormal_taste_sensitivity0.87697254
104MP0002161_abnormal_fertility/fecundity0.86527361
105MP0001501_abnormal_sleep_pattern0.85635516
106MP0003111_abnormal_nucleus_morphology0.84039765
107MP0001502_abnormal_circadian_rhythm0.83418128
108MP0004147_increased_porphyrin_level0.82712694
109MP0002102_abnormal_ear_morphology0.81778821
110MP0004381_abnormal_hair_follicle0.81763072
111MP0001145_abnormal_male_reproductive0.81639457
112MP0002876_abnormal_thyroid_physiology0.81002550
113MP0003121_genomic_imprinting0.80219589
114MP0010030_abnormal_orbit_morphology0.79879453
115MP0000427_abnormal_hair_cycle0.79496987
116MP0008789_abnormal_olfactory_epithelium0.79376024
117MP0002909_abnormal_adrenal_gland0.78914956
118MP0003077_abnormal_cell_cycle0.76980277
119MP0000647_abnormal_sebaceous_gland0.76780525
120MP0008260_abnormal_autophagy0.76228230
121MP0002822_catalepsy0.75616286
122MP0002938_white_spotting0.74228462
123MP0002233_abnormal_nose_morphology0.73542274
124MP0002928_abnormal_bile_duct0.73400980
125MP0000653_abnormal_sex_gland0.72924171
126MP0003755_abnormal_palate_morphology0.72820464
127MP0004215_abnormal_myocardial_fiber0.69206350
128MP0005391_vision/eye_phenotype0.68387941

Predicted human phenotypes

RankGene SetZ-score
1Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.63656789
2Degeneration of the lateral corticospinal tracts (HP:0002314)5.63656789
3Abnormality of the corticospinal tract (HP:0002492)4.52567833
4Neurofibrillary tangles (HP:0002185)4.46756304
5Peripheral hypomyelination (HP:0007182)4.10590706
6Sensory axonal neuropathy (HP:0003390)3.86909229
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.76920912
8Spastic gait (HP:0002064)3.60713761
9Myokymia (HP:0002411)3.57776358
10Dynein arm defect of respiratory motile cilia (HP:0012255)3.49036798
11Absent/shortened dynein arms (HP:0200106)3.49036798
12Alacrima (HP:0000522)3.47175434
13True hermaphroditism (HP:0010459)3.46431307
14Cerebral hypomyelination (HP:0006808)3.42934110
15Amyotrophic lateral sclerosis (HP:0007354)3.39757166
16Pancreatic fibrosis (HP:0100732)3.34285631
17Abnormal auditory evoked potentials (HP:0006958)3.32911414
18Cerebral inclusion bodies (HP:0100314)3.32705112
19Pancreatic cysts (HP:0001737)3.19149180
20Molar tooth sign on MRI (HP:0002419)3.17944669
21Abnormality of midbrain morphology (HP:0002418)3.17944669
22Insidious onset (HP:0003587)3.13743893
23Termporal pattern (HP:0011008)3.13743893
24Onion bulb formation (HP:0003383)3.13400940
25Supranuclear gaze palsy (HP:0000605)3.11473638
26Volvulus (HP:0002580)3.02687143
27Ankle clonus (HP:0011448)3.02221327
28Hyperventilation (HP:0002883)3.01964336
29Decreased lacrimation (HP:0000633)2.96399613
30Dysmetria (HP:0001310)2.95486338
31Abnormality of the lower motor neuron (HP:0002366)2.92344109
32Medial flaring of the eyebrow (HP:0010747)2.89819043
33Parakeratosis (HP:0001036)2.84461930
34Intention tremor (HP:0002080)2.83972632
35Abnormal respiratory motile cilium physiology (HP:0012261)2.73880097
36Drooling (HP:0002307)2.69950230
37Febrile seizures (HP:0002373)2.64852231
38Anteriorly placed anus (HP:0001545)2.63496310
39Abnormality of the anterior horn cell (HP:0006802)2.63309831
40Degeneration of anterior horn cells (HP:0002398)2.63309831
41Congenital primary aphakia (HP:0007707)2.63239385
42Progressive cerebellar ataxia (HP:0002073)2.62728722
43Absent septum pellucidum (HP:0001331)2.56591933
44Split foot (HP:0001839)2.52471223
45Absent speech (HP:0001344)2.52220925
46Abnormality of the renal medulla (HP:0100957)2.49207242
47Focal motor seizures (HP:0011153)2.49062301
48Tubulointerstitial nephritis (HP:0001970)2.48525538
49Abnormal ciliary motility (HP:0012262)2.46876584
50Hypoplastic pelvis (HP:0008839)2.43808945
51Nephrogenic diabetes insipidus (HP:0009806)2.43024712
52Scanning speech (HP:0002168)2.42734223
53Excessive salivation (HP:0003781)2.41938741
54Lower limb muscle weakness (HP:0007340)2.41527966
55Chronic hepatic failure (HP:0100626)2.38720897
56Megalencephaly (HP:0001355)2.35476679
57Atrophy/Degeneration involving motor neurons (HP:0007373)2.33713895
58Aplasia involving bones of the extremities (HP:0009825)2.33291622
59Aplasia involving bones of the upper limbs (HP:0009823)2.33291622
60Aplasia of the phalanges of the hand (HP:0009802)2.33291622
61Retinal dysplasia (HP:0007973)2.30991680
62Thickened helices (HP:0000391)2.29787641
63Abnormal respiratory epithelium morphology (HP:0012253)2.25759344
64Abnormal respiratory motile cilium morphology (HP:0005938)2.25759344
65Dialeptic seizures (HP:0011146)2.25660581
66Occipital encephalocele (HP:0002085)2.24396067
67Gaze-evoked nystagmus (HP:0000640)2.21453964
68Cystic liver disease (HP:0006706)2.20730532
69CNS hypomyelination (HP:0003429)2.20454061
70Abnormality of the septum pellucidum (HP:0007375)2.20258394
71Esophageal atresia (HP:0002032)2.20216084
72Urinary urgency (HP:0000012)2.17625172
73Chronic bronchitis (HP:0004469)2.15261575
74Morphological abnormality of the inner ear (HP:0011390)2.14746384
75Postaxial foot polydactyly (HP:0001830)2.14046083
76Action tremor (HP:0002345)2.12196390
77Coronal craniosynostosis (HP:0004440)2.12167178
78Poor coordination (HP:0002370)2.11465702
79Bronchiectasis (HP:0002110)2.10759763
80Clonus (HP:0002169)2.10629921
81Genetic anticipation (HP:0003743)2.10340362
82Vaginal atresia (HP:0000148)2.08896020
83Genital tract atresia (HP:0001827)2.08310800
84Decreased motor nerve conduction velocity (HP:0003431)2.07661474
85Focal seizures (HP:0007359)2.07630445
86Abnormality of the renal cortex (HP:0011035)2.07360450
87Clumsiness (HP:0002312)2.06310161
88Akinesia (HP:0002304)2.05644696
89Abnormality of the phalanges of the 2nd finger (HP:0009541)2.04910235
90Bell-shaped thorax (HP:0001591)2.03113022
91Aqueductal stenosis (HP:0002410)2.02909702
92Overriding aorta (HP:0002623)2.00291338
93Bowel incontinence (HP:0002607)1.99443886
94Spastic tetraparesis (HP:0001285)1.99437168
95Abnormality of chromosome stability (HP:0003220)1.98525006
96Urinary bladder sphincter dysfunction (HP:0002839)1.98143233
97Hemiparesis (HP:0001269)1.97861347
98Chromsome breakage (HP:0040012)1.97189893
99Sclerocornea (HP:0000647)1.95922586
100Cortical dysplasia (HP:0002539)1.95671184
101Lissencephaly (HP:0001339)1.94397046
102Epileptic encephalopathy (HP:0200134)1.93953094
103Postaxial hand polydactyly (HP:0001162)1.93947375
104Nephronophthisis (HP:0000090)1.92910149
105Abnormality of the labia minora (HP:0012880)1.92669299
106Pheochromocytoma (HP:0002666)1.91527104
107Absence seizures (HP:0002121)1.91091472
108Aplasia/Hypoplasia of the tongue (HP:0010295)1.90924619
109Epileptiform EEG discharges (HP:0011182)1.90905431
110Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.89801565
111Hypsarrhythmia (HP:0002521)1.87664411
112Aplasia/Hypoplasia of the tibia (HP:0005772)1.85484038
113Glioma (HP:0009733)1.85294023
114Atonic seizures (HP:0010819)1.85177266
115Rhinitis (HP:0012384)1.84611722
116Foot dorsiflexor weakness (HP:0009027)1.84611338
117Intestinal atresia (HP:0011100)1.84325376
118Oculomotor apraxia (HP:0000657)1.84174539
119Intellectual disability, moderate (HP:0002342)1.83934965
120Preaxial hand polydactyly (HP:0001177)1.83550326
121EEG with generalized epileptiform discharges (HP:0011198)1.83544778
122Anencephaly (HP:0002323)1.82401487
123Morphological abnormality of the pyramidal tract (HP:0002062)1.82153445
124Chromosomal breakage induced by crosslinking agents (HP:0003221)1.82147596
125Astrocytoma (HP:0009592)1.81910436
126Abnormality of the astrocytes (HP:0100707)1.81910436
127Dysdiadochokinesis (HP:0002075)1.81594624
128Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.81592140
129Inability to walk (HP:0002540)1.80788990
130Abnormal large intestine physiology (HP:0012700)1.80458804
131Aplasia/Hypoplasia of the uvula (HP:0010293)1.80123779
132Partial agenesis of the corpus callosum (HP:0001338)1.79480212
133Congenital hepatic fibrosis (HP:0002612)1.77874518
134Impaired vibration sensation in the lower limbs (HP:0002166)1.77483722
135Abnormality of the foot musculature (HP:0001436)1.75877520
136Slow saccadic eye movements (HP:0000514)1.75679164
137Chin dimple (HP:0010751)1.75256763
138Septo-optic dysplasia (HP:0100842)1.74826316
139Segmental peripheral demyelination/remyelination (HP:0003481)1.74102791
140Premature skin wrinkling (HP:0100678)1.73325163
141Limb dystonia (HP:0002451)1.73009797
142Medulloblastoma (HP:0002885)1.72795543
143Generalized tonic-clonic seizures (HP:0002069)1.71518484
144Specific learning disability (HP:0001328)1.71177194
145Protruding tongue (HP:0010808)1.70781805
146Type II lissencephaly (HP:0007260)1.70157996
147Autoamputation (HP:0001218)1.70021874
148Widely spaced teeth (HP:0000687)1.69978151
149Oligodactyly (hands) (HP:0001180)1.69503956
150Renal cortical cysts (HP:0000803)1.69459354
151Abnormality of the salivary glands (HP:0010286)1.69400850
152Male pseudohermaphroditism (HP:0000037)1.68397638
153Hammertoe (HP:0001765)1.68247825
154Progressive inability to walk (HP:0002505)1.66819586
155Impaired vibratory sensation (HP:0002495)1.66333211
156Narrow forehead (HP:0000341)1.65946434
157Meckel diverticulum (HP:0002245)1.65619382
158Humeroradial synostosis (HP:0003041)1.65530727
159Synostosis involving the elbow (HP:0003938)1.65530727
160Cupped ear (HP:0000378)1.65406702
161Leukodystrophy (HP:0002415)1.64587421
162Abnormality of the middle phalanges of the toes (HP:0010183)1.64041914
163Poor speech (HP:0002465)1.63969309
164Sloping forehead (HP:0000340)1.63827298
165Broad-based gait (HP:0002136)1.63704936
166Gastrointestinal atresia (HP:0002589)1.63489444
167Broad distal phalanx of finger (HP:0009836)1.63487735
168Ependymoma (HP:0002888)1.63288660
169Gait imbalance (HP:0002141)1.60509910

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.61500509
2OXSR13.84627717
3MAP4K22.68329240
4PNCK2.62343453
5PRPF4B2.54632284
6TRIM282.50770524
7BCR2.50761847
8FGFR22.50655503
9ICK2.38706441
10FRK2.24817072
11WNK12.23757801
12PKN12.14387817
13MAP2K72.12142372
14WNK42.08820321
15WNK32.08456926
16PINK12.05253504
17CDK191.95179378
18LIMK11.91142684
19WEE11.88397348
20NEK61.86692311
21EPHB11.86500941
22TESK21.86362213
23UHMK11.85171603
24PAK61.82994392
25ERBB31.79641182
26TYRO31.70549158
27MET1.68097555
28CSNK1A1L1.65265548
29MARK11.61563984
30CSNK1G31.59484229
31CCNB11.56977409
32EPHA41.56886258
33PRKD31.55295142
34NTRK11.47857160
35TSSK61.46429045
36CASK1.38018681
37CAMK2B1.37911106
38MAPKAPK51.36264390
39TNIK1.34767227
40CSNK1G21.33527651
41SIK21.30358360
42CAMKK21.28710393
43ROCK21.28436676
44PBK1.27785485
45CSNK1G11.22915070
46SGK4941.20844632
47SGK2231.20844632
48CLK11.17083236
49SRPK11.14525658
50PLK21.14449839
51BRSK21.13135705
52MARK21.06908128
53NTRK21.05412341
54PLK31.04629663
55MAP2K41.03910424
56TTK1.03857352
57CAMK2D1.03291259
58EPHA31.02379993
59VRK11.01182669
60FGR0.99232803
61DYRK20.96845632
62CDK50.95240024
63CDK140.95041097
64PAK30.94974878
65CDC70.94257034
66SGK20.93710831
67ZAK0.92687196
68CDK150.90852344
69CDK180.88348212
70NTRK30.86851896
71INSRR0.85450675
72PDK40.84922980
73PDK30.84922980
74PLK40.81205889
75PRKCG0.80906042
76CDK11A0.80360400
77ATR0.79794825
78ERBB40.78707703
79PHKG10.78234230
80PHKG20.78234230
81PLK10.78167377
82CDK30.77183195
83PDK20.77179425
84DYRK30.76928295
85MAPK130.76498554
86CAMK2G0.76190710
87ATM0.75444038
88CDK60.75389916
89EIF2AK30.74360502
90TAOK30.73863756
91CSNK1D0.72998580
92CAMK1G0.71185799
93CAMK2A0.68838631
94MINK10.68771776
95MAPK150.68341116
96MAP3K40.65413894
97BRSK10.64886706
98LATS10.64774358
99KSR20.63572934
100CAMKK10.62470027
101DYRK1A0.61260003
102DAPK20.60329193
103CHEK20.58350729
104CAMK40.57224637
105STK38L0.56635635
106NEK20.55718848
107DMPK0.54879265
108MAP3K90.54666248
109CDK120.53388981
110MKNK10.53141541
111MAPK100.52903963
112STK110.51166842
113PTK2B0.50384563
114PRKDC0.49414954
115ADRBK20.47857135
116CSNK1E0.46726685
117TRPM70.46510134
118PDPK10.46319520
119PRKD10.46304077
120NUAK10.46073776
121RPS6KA40.44847553
122EIF2AK10.44576958
123NEK10.44001009
124PRKCQ0.43838642
125CDK20.43147193
126PRKCH0.43000332
127DDR20.42682154
128KSR10.42474762
129RPS6KA30.42070443
130BUB10.41826035
131PRKG10.41706196
132FYN0.41638403
133BRD40.40873876
134PRKACB0.40545389
135MKNK20.39233419
136GSK3B0.39049522
137MELK0.38421258
138CSNK1A10.37669925
139IRAK20.37343518
140PDGFRB0.37285463
141CDK10.36724022
142BMPR1B0.36289496
143ALK0.35530023
144MAP3K130.35461385
145CHEK10.33690529
146PRKCE0.32803129
147SGK10.32213444
148PDK10.32053374

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.49987413
2Steroid biosynthesis_Homo sapiens_hsa001002.81999664
3Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.56410268
4Ether lipid metabolism_Homo sapiens_hsa005652.50687896
5Axon guidance_Homo sapiens_hsa043602.45985778
6Protein export_Homo sapiens_hsa030602.45217661
7Fatty acid elongation_Homo sapiens_hsa000622.30477656
8Vitamin B6 metabolism_Homo sapiens_hsa007502.27441315
9Glutamatergic synapse_Homo sapiens_hsa047242.09862324
10GABAergic synapse_Homo sapiens_hsa047272.05322214
11Phototransduction_Homo sapiens_hsa047441.95464661
12Mismatch repair_Homo sapiens_hsa034301.84041171
13Dorso-ventral axis formation_Homo sapiens_hsa043201.83230003
14Morphine addiction_Homo sapiens_hsa050321.80216073
15Olfactory transduction_Homo sapiens_hsa047401.73857943
16Nicotine addiction_Homo sapiens_hsa050331.68556535
17Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67867903
18Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.62679849
19Circadian entrainment_Homo sapiens_hsa047131.58238356
20Serotonergic synapse_Homo sapiens_hsa047261.57597875
21Homologous recombination_Homo sapiens_hsa034401.54931703
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.48612838
23Sphingolipid metabolism_Homo sapiens_hsa006001.46676551
24Dopaminergic synapse_Homo sapiens_hsa047281.46177218
25Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.46004367
26Circadian rhythm_Homo sapiens_hsa047101.44408829
27Long-term depression_Homo sapiens_hsa047301.44288244
28Tight junction_Homo sapiens_hsa045301.42869281
29Synaptic vesicle cycle_Homo sapiens_hsa047211.41608933
30Hedgehog signaling pathway_Homo sapiens_hsa043401.41139373
31Cell cycle_Homo sapiens_hsa041101.40957339
32Renal cell carcinoma_Homo sapiens_hsa052111.37242697
33Amphetamine addiction_Homo sapiens_hsa050311.30782169
34Nitrogen metabolism_Homo sapiens_hsa009101.30158147
35Salivary secretion_Homo sapiens_hsa049701.29924258
36Cocaine addiction_Homo sapiens_hsa050301.29593425
37Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29092356
38Linoleic acid metabolism_Homo sapiens_hsa005911.26056333
39Butanoate metabolism_Homo sapiens_hsa006501.25199138
40RNA degradation_Homo sapiens_hsa030181.23806168
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23332445
42Long-term potentiation_Homo sapiens_hsa047201.17755020
43Cholinergic synapse_Homo sapiens_hsa047251.17121534
44RNA polymerase_Homo sapiens_hsa030201.16200138
45ErbB signaling pathway_Homo sapiens_hsa040121.15405037
46Gastric acid secretion_Homo sapiens_hsa049711.14623175
47Oocyte meiosis_Homo sapiens_hsa041141.14043050
48Propanoate metabolism_Homo sapiens_hsa006401.13884552
49alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.12328873
50Regulation of autophagy_Homo sapiens_hsa041401.08455848
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.07603319
52DNA replication_Homo sapiens_hsa030301.06877161
53beta-Alanine metabolism_Homo sapiens_hsa004101.06204552
54Phospholipase D signaling pathway_Homo sapiens_hsa040721.05021852
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.04712501
56Base excision repair_Homo sapiens_hsa034101.03533400
57Taste transduction_Homo sapiens_hsa047421.03278410
58Wnt signaling pathway_Homo sapiens_hsa043101.03124429
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.02322572
60Nucleotide excision repair_Homo sapiens_hsa034201.02206536
61Sphingolipid signaling pathway_Homo sapiens_hsa040711.01309518
62Alcoholism_Homo sapiens_hsa050341.00963049
63Huntingtons disease_Homo sapiens_hsa050161.00951062
64Gap junction_Homo sapiens_hsa045400.99450809
65Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.97796225
66Endocytosis_Homo sapiens_hsa041440.96770826
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.96578424
68Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.96120312
69Basal cell carcinoma_Homo sapiens_hsa052170.96062066
70Vascular smooth muscle contraction_Homo sapiens_hsa042700.96037619
71RNA transport_Homo sapiens_hsa030130.95482837
72Spliceosome_Homo sapiens_hsa030400.95213757
73Renin secretion_Homo sapiens_hsa049240.94456172
74Ras signaling pathway_Homo sapiens_hsa040140.92755404
75Basal transcription factors_Homo sapiens_hsa030220.92262881
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88918057
77Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.86701509
78Hippo signaling pathway_Homo sapiens_hsa043900.85533307
79Oxytocin signaling pathway_Homo sapiens_hsa049210.83905663
80cAMP signaling pathway_Homo sapiens_hsa040240.83464416
81Insulin secretion_Homo sapiens_hsa049110.83217469
82Ovarian steroidogenesis_Homo sapiens_hsa049130.82670356
83Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82182174
84Vibrio cholerae infection_Homo sapiens_hsa051100.81955959
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81943251
86Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81574402
87Glycerophospholipid metabolism_Homo sapiens_hsa005640.79405555
88Melanogenesis_Homo sapiens_hsa049160.77345446
89MAPK signaling pathway_Homo sapiens_hsa040100.73539033
90Choline metabolism in cancer_Homo sapiens_hsa052310.71594522
91Parkinsons disease_Homo sapiens_hsa050120.70896701
92Collecting duct acid secretion_Homo sapiens_hsa049660.70684055
93Calcium signaling pathway_Homo sapiens_hsa040200.67350409
94Oxidative phosphorylation_Homo sapiens_hsa001900.65866956
95mRNA surveillance pathway_Homo sapiens_hsa030150.64830053
96Inositol phosphate metabolism_Homo sapiens_hsa005620.63851259
97Estrogen signaling pathway_Homo sapiens_hsa049150.63217875
98ABC transporters_Homo sapiens_hsa020100.63043635
99Pancreatic secretion_Homo sapiens_hsa049720.62813647
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.62465379
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61798578
102Cardiac muscle contraction_Homo sapiens_hsa042600.60583256
103Selenocompound metabolism_Homo sapiens_hsa004500.60078151
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60018870
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59744125
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.59294085
107Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59282431
108Fatty acid biosynthesis_Homo sapiens_hsa000610.58042891
109Purine metabolism_Homo sapiens_hsa002300.57272244
110Peroxisome_Homo sapiens_hsa041460.57272224
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56766762
112p53 signaling pathway_Homo sapiens_hsa041150.56533416
113GnRH signaling pathway_Homo sapiens_hsa049120.56253128
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.56105462
115Histidine metabolism_Homo sapiens_hsa003400.54249176
116Maturity onset diabetes of the young_Homo sapiens_hsa049500.53729602
117Sulfur metabolism_Homo sapiens_hsa009200.52988995
118Aldosterone synthesis and secretion_Homo sapiens_hsa049250.52765971
119Non-homologous end-joining_Homo sapiens_hsa034500.52090157
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.49318282
121Rap1 signaling pathway_Homo sapiens_hsa040150.49086281
122Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.48689935
123Pyrimidine metabolism_Homo sapiens_hsa002400.46493305
124Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45888739
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45308679
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45180435
127Mineral absorption_Homo sapiens_hsa049780.41718924
128Thyroid hormone synthesis_Homo sapiens_hsa049180.41081051
129Arginine and proline metabolism_Homo sapiens_hsa003300.39150214
130Arachidonic acid metabolism_Homo sapiens_hsa005900.38434055
131Fanconi anemia pathway_Homo sapiens_hsa034600.37866210
132Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.37744241
133Alzheimers disease_Homo sapiens_hsa050100.37103871
134Type II diabetes mellitus_Homo sapiens_hsa049300.34548815
135Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.34167877
136Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.30502747
137Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30209335

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