Rank | Gene Set | Z-score |
---|---|---|
1 | establishment of protein localization to Golgi (GO:0072600) | 3.77211812 |
2 | response to inactivity (GO:0014854) | 3.70182662 |
3 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.56663881 |
4 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.54328359 |
5 | negative regulation of neurotransmitter transport (GO:0051589) | 3.52796677 |
6 | muscle filament sliding (GO:0030049) | 3.44864357 |
7 | actin-myosin filament sliding (GO:0033275) | 3.44864357 |
8 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.32055747 |
9 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.29690256 |
10 | cell communication involved in cardiac conduction (GO:0086065) | 3.26133041 |
11 | plasma membrane repair (GO:0001778) | 3.25266279 |
12 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.22646740 |
13 | locomotory exploration behavior (GO:0035641) | 3.20765442 |
14 | myofibril assembly (GO:0030239) | 3.16763622 |
15 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 3.13453491 |
16 | proline transport (GO:0015824) | 3.13013175 |
17 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.11227392 |
18 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.10504287 |
19 | actin-mediated cell contraction (GO:0070252) | 3.05960718 |
20 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 2.97157424 |
21 | synaptic vesicle maturation (GO:0016188) | 2.96941377 |
22 | cell communication by electrical coupling (GO:0010644) | 2.96029969 |
23 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.95068489 |
24 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.93736111 |
25 | cardiac muscle hypertrophy (GO:0003300) | 2.90927694 |
26 | striated muscle contraction (GO:0006941) | 2.87269429 |
27 | cellular response to epinephrine stimulus (GO:0071872) | 2.84135425 |
28 | regulation of cell communication by electrical coupling (GO:0010649) | 2.83054223 |
29 | postsynaptic membrane organization (GO:0001941) | 2.82303931 |
30 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.79364404 |
31 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.77600053 |
32 | glutamate secretion (GO:0014047) | 2.77595641 |
33 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.77278256 |
34 | dendrite morphogenesis (GO:0048813) | 2.75448583 |
35 | striated muscle hypertrophy (GO:0014897) | 2.74665565 |
36 | sodium ion export (GO:0071436) | 2.73713663 |
37 | layer formation in cerebral cortex (GO:0021819) | 2.73392139 |
38 | activation of protein kinase A activity (GO:0034199) | 2.72212266 |
39 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.71108702 |
40 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.71045280 |
41 | actin filament-based movement (GO:0030048) | 2.66684801 |
42 | cell migration in hindbrain (GO:0021535) | 2.66547517 |
43 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 2.61369814 |
44 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.60910149 |
45 | protein localization to Golgi apparatus (GO:0034067) | 2.58600040 |
46 | neuronal action potential propagation (GO:0019227) | 2.57405258 |
47 | vocalization behavior (GO:0071625) | 2.57399347 |
48 | synaptic vesicle exocytosis (GO:0016079) | 2.56150734 |
49 | regulation of membrane repolarization (GO:0060306) | 2.55176208 |
50 | carnitine shuttle (GO:0006853) | 2.54447960 |
51 | response to epinephrine (GO:0071871) | 2.53586722 |
52 | cellular potassium ion homeostasis (GO:0030007) | 2.53424741 |
53 | neuron cell-cell adhesion (GO:0007158) | 2.53421525 |
54 | membrane depolarization during action potential (GO:0086010) | 2.53210698 |
55 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.52795495 |
56 | regulation of striated muscle contraction (GO:0006942) | 2.50686537 |
57 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.49752781 |
58 | neuron recognition (GO:0008038) | 2.49716370 |
59 | myoblast fusion (GO:0007520) | 2.48664450 |
60 | presynaptic membrane organization (GO:0097090) | 2.48466209 |
61 | axonal fasciculation (GO:0007413) | 2.47817357 |
62 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.47042694 |
63 | regulation of skeletal muscle cell differentiation (GO:2001014) | 2.46409549 |
64 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.44947011 |
65 | nucleus localization (GO:0051647) | 2.44625297 |
66 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.44332097 |
67 | regulation of synapse structural plasticity (GO:0051823) | 2.44111194 |
68 | regulation of actin filament-based movement (GO:1903115) | 2.43819394 |
69 | neuromuscular synaptic transmission (GO:0007274) | 2.42992805 |
70 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.42570458 |
71 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.41813385 |
72 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.40645680 |
73 | regulation of relaxation of muscle (GO:1901077) | 2.39275261 |
74 | negative regulation of potassium ion transport (GO:0043267) | 2.39267777 |
75 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 2.39048210 |
76 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.38876371 |
77 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.38279554 |
78 | exploration behavior (GO:0035640) | 2.37406576 |
79 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 2.36857913 |
80 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 2.36857913 |
81 | regulation of the force of heart contraction (GO:0002026) | 2.36594327 |
82 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.36014093 |
83 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.35700358 |
84 | potassium ion import (GO:0010107) | 2.34204804 |
85 | skeletal muscle contraction (GO:0003009) | 2.34080327 |
86 | positive regulation of axon extension (GO:0045773) | 2.32797030 |
87 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.32256570 |
88 | muscle hypertrophy in response to stress (GO:0003299) | 2.32256570 |
89 | cardiac muscle adaptation (GO:0014887) | 2.32256570 |
90 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.32001859 |
91 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 2.31681067 |
92 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.31637252 |
93 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.31637252 |
94 | presynaptic membrane assembly (GO:0097105) | 2.30686639 |
95 | nerve growth factor signaling pathway (GO:0038180) | 2.30252303 |
96 | positive regulation of potassium ion transport (GO:0043268) | 2.30105606 |
97 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.29305654 |
98 | fatty acid transmembrane transport (GO:1902001) | 2.28797497 |
99 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.28644761 |
100 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.28225227 |
101 | negative regulation of vascular permeability (GO:0043116) | 2.27623930 |
102 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 2.27460389 |
103 | cardiac myofibril assembly (GO:0055003) | 2.27321377 |
104 | negative regulation of inclusion body assembly (GO:0090084) | 2.26905302 |
105 | muscle hypertrophy (GO:0014896) | 2.26856272 |
106 | vesicle transport along microtubule (GO:0047496) | 2.26822513 |
107 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.26581824 |
108 | establishment of nucleus localization (GO:0040023) | 2.26552242 |
109 | growth hormone receptor signaling pathway (GO:0060396) | 2.26329863 |
110 | detection of temperature stimulus (GO:0016048) | 2.25939193 |
111 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.25319621 |
112 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.25261931 |
113 | regulation of sarcomere organization (GO:0060297) | 2.24899449 |
114 | macroautophagy (GO:0016236) | 2.24260321 |
115 | neuronal ion channel clustering (GO:0045161) | 2.24209683 |
116 | positive regulation of sodium ion transport (GO:0010765) | 2.23790226 |
117 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.23344464 |
118 | regulation of potassium ion transmembrane transport (GO:1901379) | 2.22421177 |
119 | axon extension (GO:0048675) | 2.21686322 |
120 | organelle transport along microtubule (GO:0072384) | 2.19900095 |
121 | protein targeting to Golgi (GO:0000042) | 2.19877379 |
122 | protein targeting to plasma membrane (GO:0072661) | 2.19284857 |
123 | neurofilament cytoskeleton organization (GO:0060052) | 2.19158684 |
124 | protein localization to endosome (GO:0036010) | 2.19078871 |
125 | actomyosin structure organization (GO:0031032) | 2.18938444 |
126 | syncytium formation by plasma membrane fusion (GO:0000768) | 2.18622174 |
127 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.18319951 |
128 | membrane assembly (GO:0071709) | 2.17749238 |
129 | negative regulation of protein localization to cell surface (GO:2000009) | 2.15749390 |
130 | regulation of sodium ion transmembrane transporter activity (GO:2000649) | 2.14020101 |
131 | regulation of synaptic vesicle transport (GO:1902803) | 2.11959636 |
132 | neurotransmitter secretion (GO:0007269) | 2.11767100 |
133 | protein localization to synapse (GO:0035418) | 2.11714806 |
134 | sarcomere organization (GO:0045214) | 2.10988174 |
135 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.10695372 |
136 | amino-acid betaine transport (GO:0015838) | 2.10378781 |
137 | carnitine transport (GO:0015879) | 2.10378781 |
138 | regulation of axon guidance (GO:1902667) | 2.09529875 |
139 | relaxation of cardiac muscle (GO:0055119) | 2.09458629 |
140 | carnitine transmembrane transport (GO:1902603) | 2.09301900 |
141 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.08734909 |
142 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.06484404 |
143 | cellular sodium ion homeostasis (GO:0006883) | 2.06114904 |
144 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 2.06011126 |
145 | cardiac muscle contraction (GO:0060048) | 2.05936234 |
146 | neuromuscular process controlling balance (GO:0050885) | 2.05729162 |
147 | membrane repolarization (GO:0086009) | 2.04551479 |
148 | innervation (GO:0060384) | 2.04463293 |
149 | detection of calcium ion (GO:0005513) | 2.04227410 |
150 | regulation of cardiac muscle contraction (GO:0055117) | 2.02967589 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.12113483 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.46507158 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.28123343 |
4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.26578725 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.23540647 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.07459019 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.07115546 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.07115546 |
9 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.98695034 |
10 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.96516837 |
11 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.93959154 |
12 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.87731128 |
13 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.86709762 |
14 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.84548532 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.83578977 |
16 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.80452367 |
17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.79085717 |
18 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.78354903 |
19 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.77834270 |
20 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.72636922 |
21 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.69996441 |
22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.68677635 |
23 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.60633796 |
24 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.60105112 |
25 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.57808129 |
26 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.56593128 |
27 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.54512585 |
28 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.53094120 |
29 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52903854 |
30 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.52183792 |
31 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.51830268 |
32 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.50039194 |
33 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.49813698 |
34 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.45629543 |
35 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.45575454 |
36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.44406032 |
37 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.42507708 |
38 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.42215950 |
39 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.39782323 |
40 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.36898080 |
41 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.36008158 |
42 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.33474435 |
43 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.33086123 |
44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31210807 |
45 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.31127373 |
46 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.29690783 |
47 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.29322448 |
48 | FUS_26573619_Chip-Seq_HEK293_Human | 1.27409955 |
49 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.26926403 |
50 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.26828665 |
51 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26448815 |
52 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.25628447 |
53 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.25364490 |
54 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.25239347 |
55 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.25123521 |
56 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25042225 |
57 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.23873845 |
58 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.23600695 |
59 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.23472883 |
60 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.22258771 |
61 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.19445369 |
62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.19068755 |
63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17788574 |
64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17788574 |
65 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.17104055 |
66 | TP53_16413492_ChIP-PET_HCT116_Human | 1.16667458 |
67 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.16485833 |
68 | STAT3_23295773_ChIP-Seq_U87_Human | 1.16056542 |
69 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.14589332 |
70 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.14186550 |
71 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14095384 |
72 | P300_19829295_ChIP-Seq_ESCs_Human | 1.12475301 |
73 | AR_25329375_ChIP-Seq_VCAP_Human | 1.12464136 |
74 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.12236385 |
75 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.10336003 |
76 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.10336003 |
77 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.10295637 |
78 | KDM2B_26808549_Chip-Seq_REH_Human | 1.09772789 |
79 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.09318436 |
80 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.08822224 |
81 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.08584314 |
82 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07264144 |
83 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.06900117 |
84 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.06708976 |
85 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.06196187 |
86 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.05599410 |
87 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.05484206 |
88 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.05079634 |
89 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.04555206 |
90 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.04551568 |
91 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.04477723 |
92 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04433481 |
93 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.04401843 |
94 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.04302091 |
95 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.03913195 |
96 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.03214076 |
97 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03041050 |
98 | AR_19668381_ChIP-Seq_PC3_Human | 1.02996169 |
99 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.01395369 |
100 | CJUN_26792858_Chip-Seq_BT549_Human | 1.01297063 |
101 | RXR_22108803_ChIP-Seq_LS180_Human | 1.00869680 |
102 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.99214142 |
103 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98942728 |
104 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.97403418 |
105 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.97108271 |
106 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.96728868 |
107 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.96558039 |
108 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96167351 |
109 | KDM2B_26808549_Chip-Seq_K562_Human | 0.95501796 |
110 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.95021009 |
111 | TCF4_23295773_ChIP-Seq_U87_Human | 0.95008673 |
112 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.94985373 |
113 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.94223860 |
114 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.93056899 |
115 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.91998520 |
116 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91998520 |
117 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91404362 |
118 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.91365372 |
119 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.91221650 |
120 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.91147007 |
121 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.91147007 |
122 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.90453580 |
123 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.89925367 |
124 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.89919789 |
125 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.89482811 |
126 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.89380421 |
127 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.89264594 |
128 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.88117694 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 3.54622336 |
2 | MP0004270_analgesia | 3.30767228 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 2.92770295 |
4 | MP0002735_abnormal_chemical_nociception | 2.82474417 |
5 | MP0000751_myopathy | 2.81367868 |
6 | MP0000569_abnormal_digit_pigmentation | 2.61888179 |
7 | MP0001968_abnormal_touch/_nociception | 2.54556334 |
8 | MP0004858_abnormal_nervous_system | 2.42083667 |
9 | MP0004084_abnormal_cardiac_muscle | 2.33899027 |
10 | MP0002734_abnormal_mechanical_nocicepti | 2.27654732 |
11 | MP0003646_muscle_fatigue | 2.25260409 |
12 | MP0004215_abnormal_myocardial_fiber | 2.23652677 |
13 | MP0002332_abnormal_exercise_endurance | 2.20041196 |
14 | MP0003635_abnormal_synaptic_transmissio | 2.19755964 |
15 | MP0004130_abnormal_muscle_cell | 2.15290773 |
16 | MP0003880_abnormal_central_pattern | 2.11577878 |
17 | MP0004036_abnormal_muscle_relaxation | 2.08153153 |
18 | MP0002736_abnormal_nociception_after | 2.03943861 |
19 | MP0002733_abnormal_thermal_nociception | 1.92649394 |
20 | MP0005670_abnormal_white_adipose | 1.87613986 |
21 | MP0009046_muscle_twitch | 1.79518916 |
22 | MP0005623_abnormal_meninges_morphology | 1.78608182 |
23 | MP0001348_abnormal_lacrimal_gland | 1.75951086 |
24 | MP0002063_abnormal_learning/memory/cond | 1.71393093 |
25 | MP0002254_reproductive_system_inflammat | 1.70644783 |
26 | MP0006276_abnormal_autonomic_nervous | 1.69406132 |
27 | MP0009780_abnormal_chondrocyte_physiolo | 1.68332029 |
28 | MP0009745_abnormal_behavioral_response | 1.67283980 |
29 | MP0003329_amyloid_beta_deposits | 1.66323472 |
30 | MP0000778_abnormal_nervous_system | 1.66118285 |
31 | MP0005167_abnormal_blood-brain_barrier | 1.63257770 |
32 | MP0002272_abnormal_nervous_system | 1.62764318 |
33 | MP0002972_abnormal_cardiac_muscle | 1.60671878 |
34 | MP0001970_abnormal_pain_threshold | 1.59512943 |
35 | MP0000749_muscle_degeneration | 1.58991726 |
36 | MP0001984_abnormal_olfaction | 1.58325221 |
37 | MP0005620_abnormal_muscle_contractility | 1.58275108 |
38 | MP0008775_abnormal_heart_ventricle | 1.57485657 |
39 | MP0004510_myositis | 1.55955939 |
40 | MP0001299_abnormal_eye_distance/ | 1.54778010 |
41 | MP0004484_altered_response_of | 1.52009253 |
42 | MP0002064_seizures | 1.51402502 |
43 | MP0002234_abnormal_pharynx_morphology | 1.51069044 |
44 | MP0003787_abnormal_imprinting | 1.50190243 |
45 | MP0001486_abnormal_startle_reflex | 1.48785231 |
46 | MP0004087_abnormal_muscle_fiber | 1.48311769 |
47 | MP0004043_abnormal_pH_regulation | 1.47267142 |
48 | MP0005330_cardiomyopathy | 1.42737860 |
49 | MP0004145_abnormal_muscle_electrophysio | 1.42599030 |
50 | MP0006138_congestive_heart_failure | 1.41159888 |
51 | MP0002067_abnormal_sensory_capabilities | 1.37074372 |
52 | MP0002184_abnormal_innervation | 1.36393107 |
53 | MP0005423_abnormal_somatic_nervous | 1.35997795 |
54 | MP0003137_abnormal_impulse_conducting | 1.34236748 |
55 | MP0004085_abnormal_heartbeat | 1.32644725 |
56 | MP0002572_abnormal_emotion/affect_behav | 1.29744627 |
57 | MP0000733_abnormal_muscle_development | 1.28992560 |
58 | MP0000747_muscle_weakness | 1.26848035 |
59 | MP0002638_abnormal_pupillary_reflex | 1.25779334 |
60 | MP0003045_fibrosis | 1.25636363 |
61 | MP0004272_abnormal_basement_membrane | 1.24503908 |
62 | MP0001440_abnormal_grooming_behavior | 1.23404195 |
63 | MP0001879_abnormal_lymphatic_vessel | 1.21216087 |
64 | MP0004885_abnormal_endolymph | 1.18669471 |
65 | MP0002876_abnormal_thyroid_physiology | 1.18509385 |
66 | MP0008569_lethality_at_weaning | 1.18120555 |
67 | MP0004142_abnormal_muscle_tone | 1.17331490 |
68 | MP0005386_behavior/neurological_phenoty | 1.17140347 |
69 | MP0004924_abnormal_behavior | 1.17140347 |
70 | MP0003828_pulmonary_edema | 1.16432693 |
71 | MP0005666_abnormal_adipose_tissue | 1.13664753 |
72 | MP0005409_darkened_coat_color | 1.12466006 |
73 | MP0000920_abnormal_myelination | 1.09214343 |
74 | MP0002909_abnormal_adrenal_gland | 1.08253374 |
75 | MP0002127_abnormal_cardiovascular_syste | 1.07887491 |
76 | MP0005385_cardiovascular_system_phenoty | 1.05819127 |
77 | MP0001544_abnormal_cardiovascular_syste | 1.05819127 |
78 | MP0003879_abnormal_hair_cell | 1.04374033 |
79 | MP0002009_preneoplasia | 1.03925830 |
80 | MP0001501_abnormal_sleep_pattern | 1.02166103 |
81 | MP0001346_abnormal_lacrimal_gland | 1.01850281 |
82 | MP0002822_catalepsy | 1.01298638 |
83 | MP0002108_abnormal_muscle_morphology | 0.99990595 |
84 | MP0003690_abnormal_glial_cell | 0.99366754 |
85 | MP0004185_abnormal_adipocyte_glucose | 0.98902014 |
86 | MP0004811_abnormal_neuron_physiology | 0.97935171 |
87 | MP0002106_abnormal_muscle_physiology | 0.97750306 |
88 | MP0000955_abnormal_spinal_cord | 0.96340183 |
89 | MP0000759_abnormal_skeletal_muscle | 0.95341092 |
90 | MP0001502_abnormal_circadian_rhythm | 0.94418110 |
91 | MP0002138_abnormal_hepatobiliary_system | 0.94388197 |
92 | MP0003633_abnormal_nervous_system | 0.94159320 |
93 | MP0005369_muscle_phenotype | 0.93579302 |
94 | MP0001188_hyperpigmentation | 0.91497953 |
95 | MP0003634_abnormal_glial_cell | 0.91385962 |
96 | MP0002066_abnormal_motor_capabilities/c | 0.91109065 |
97 | MP0000013_abnormal_adipose_tissue | 0.90366459 |
98 | MP0002882_abnormal_neuron_morphology | 0.90357641 |
99 | MP0010234_abnormal_vibrissa_follicle | 0.90141512 |
100 | MP0010630_abnormal_cardiac_muscle | 0.89785300 |
101 | MP0010368_abnormal_lymphatic_system | 0.89364585 |
102 | MP0005187_abnormal_penis_morphology | 0.89158254 |
103 | MP0005535_abnormal_body_temperature | 0.87983818 |
104 | MP0005375_adipose_tissue_phenotype | 0.87346437 |
105 | MP0004233_abnormal_muscle_weight | 0.86101437 |
106 | MP0002269_muscular_atrophy | 0.85960573 |
107 | MP0000604_amyloidosis | 0.84803394 |
108 | MP0005645_abnormal_hypothalamus_physiol | 0.84775629 |
109 | MP0003279_aneurysm | 0.84080798 |
110 | MP0003091_abnormal_cell_migration | 0.82399411 |
111 | MP0003631_nervous_system_phenotype | 0.79010995 |
112 | MP0003221_abnormal_cardiomyocyte_apopto | 0.77752655 |
113 | MP0009384_cardiac_valve_regurgitation | 0.76963176 |
114 | MP0002557_abnormal_social/conspecific_i | 0.76959727 |
115 | MP0001958_emphysema | 0.76534724 |
116 | MP0000230_abnormal_systemic_arterial | 0.76430642 |
117 | MP0002971_abnormal_brown_adipose | 0.76341632 |
118 | MP0000003_abnormal_adipose_tissue | 0.75817939 |
119 | MP0000750_abnormal_muscle_regeneration | 0.75593554 |
120 | MP0008961_abnormal_basal_metabolism | 0.75525193 |
121 | MP0008874_decreased_physiological_sensi | 0.73693524 |
122 | MP0001177_atelectasis | 0.73474721 |
123 | MP0006082_CNS_inflammation | 0.66379309 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Muscle fiber inclusion bodies (HP:0100299) | 4.92634919 |
2 | Nemaline bodies (HP:0003798) | 4.85239731 |
3 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 4.79267185 |
4 | Abnormality of the left ventricular outflow tract (HP:0011103) | 4.36170755 |
5 | Subaortic stenosis (HP:0001682) | 4.36170755 |
6 | Type 1 muscle fiber predominance (HP:0003803) | 4.20718869 |
7 | Termporal pattern (HP:0011008) | 4.05203907 |
8 | Insidious onset (HP:0003587) | 4.05203907 |
9 | Hyporeflexia of lower limbs (HP:0002600) | 3.90970625 |
10 | Ulnar claw (HP:0001178) | 3.88872129 |
11 | Myokymia (HP:0002411) | 3.80858025 |
12 | Sudden death (HP:0001699) | 3.78764959 |
13 | Action tremor (HP:0002345) | 3.70921282 |
14 | Frequent falls (HP:0002359) | 3.48776794 |
15 | Asymmetric septal hypertrophy (HP:0001670) | 3.41466732 |
16 | Pheochromocytoma (HP:0002666) | 3.40729402 |
17 | Focal motor seizures (HP:0011153) | 3.25678553 |
18 | Exercise-induced myalgia (HP:0003738) | 3.09229761 |
19 | Difficulty running (HP:0009046) | 2.97687771 |
20 | Focal seizures (HP:0007359) | 2.96881009 |
21 | Calf muscle hypertrophy (HP:0008981) | 2.92962054 |
22 | Abnormality of the corticospinal tract (HP:0002492) | 2.87414599 |
23 | Neuroendocrine neoplasm (HP:0100634) | 2.84939155 |
24 | Muscle fiber splitting (HP:0003555) | 2.83455162 |
25 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.82952237 |
26 | Bundle branch block (HP:0011710) | 2.75348347 |
27 | Hammertoe (HP:0001765) | 2.66927027 |
28 | Atonic seizures (HP:0010819) | 2.66477066 |
29 | Onion bulb formation (HP:0003383) | 2.65216406 |
30 | Distal arthrogryposis (HP:0005684) | 2.65192953 |
31 | EMG: neuropathic changes (HP:0003445) | 2.64105329 |
32 | Abnormality of the calf musculature (HP:0001430) | 2.63452893 |
33 | Atrial fibrillation (HP:0005110) | 2.62151379 |
34 | Fetal akinesia sequence (HP:0001989) | 2.56766131 |
35 | Steppage gait (HP:0003376) | 2.56139681 |
36 | Prolonged QT interval (HP:0001657) | 2.54403647 |
37 | Myotonia (HP:0002486) | 2.54343473 |
38 | Syncope (HP:0001279) | 2.52364780 |
39 | Hyperkalemia (HP:0002153) | 2.51297571 |
40 | Primary atrial arrhythmia (HP:0001692) | 2.50488531 |
41 | Progressive cerebellar ataxia (HP:0002073) | 2.49057320 |
42 | Neck muscle weakness (HP:0000467) | 2.48430987 |
43 | Right ventricular cardiomyopathy (HP:0011663) | 2.48293116 |
44 | Exercise-induced muscle cramps (HP:0003710) | 2.46851044 |
45 | Urinary urgency (HP:0000012) | 2.41845080 |
46 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.38645162 |
47 | Foot dorsiflexor weakness (HP:0009027) | 2.38463577 |
48 | Supranuclear gaze palsy (HP:0000605) | 2.36908659 |
49 | Rimmed vacuoles (HP:0003805) | 2.36496842 |
50 | Cerebral hemorrhage (HP:0001342) | 2.36013510 |
51 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.35661636 |
52 | Ventricular fibrillation (HP:0001663) | 2.34741966 |
53 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.34173225 |
54 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.34173225 |
55 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.32807058 |
56 | Decreased number of peripheral myelinated nerve fibers (HP:0003380) | 2.28503365 |
57 | Supraventricular tachycardia (HP:0004755) | 2.26488921 |
58 | Supraventricular arrhythmia (HP:0005115) | 2.25521193 |
59 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 2.24286896 |
60 | Ankle clonus (HP:0011448) | 2.22925446 |
61 | Ventricular tachycardia (HP:0004756) | 2.21490564 |
62 | Broad metatarsal (HP:0001783) | 2.17379067 |
63 | Abnormality of the foot musculature (HP:0001436) | 2.17225415 |
64 | Lower limb muscle weakness (HP:0007340) | 2.16726249 |
65 | Febrile seizures (HP:0002373) | 2.16248911 |
66 | Dialeptic seizures (HP:0011146) | 2.13392819 |
67 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.09856299 |
68 | Papilledema (HP:0001085) | 2.09817765 |
69 | Ketoacidosis (HP:0001993) | 2.09412024 |
70 | Myoglobinuria (HP:0002913) | 2.05335195 |
71 | Lip pit (HP:0100267) | 2.04194268 |
72 | EMG: myopathic abnormalities (HP:0003458) | 2.04076005 |
73 | Hemiplegia (HP:0002301) | 2.03264486 |
74 | Spastic gait (HP:0002064) | 2.02080053 |
75 | Proximal amyotrophy (HP:0007126) | 2.01492761 |
76 | Ventricular arrhythmia (HP:0004308) | 2.00617913 |
77 | Increased variability in muscle fiber diameter (HP:0003557) | 1.99782865 |
78 | Areflexia of lower limbs (HP:0002522) | 1.98027005 |
79 | Heart block (HP:0012722) | 1.97833342 |
80 | Left ventricular hypertrophy (HP:0001712) | 1.97692807 |
81 | Lymphangioma (HP:0100764) | 1.97329995 |
82 | Blue irides (HP:0000635) | 1.95262191 |
83 | Scanning speech (HP:0002168) | 1.94289937 |
84 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.93758926 |
85 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.93061216 |
86 | Hyperventilation (HP:0002883) | 1.91611860 |
87 | Increased connective tissue (HP:0009025) | 1.91092990 |
88 | Neurofibrillary tangles (HP:0002185) | 1.91004650 |
89 | Truncal obesity (HP:0001956) | 1.90618792 |
90 | Hypoplasia of the iris (HP:0007676) | 1.90538733 |
91 | Atrioventricular block (HP:0001678) | 1.90390058 |
92 | Visual hallucinations (HP:0002367) | 1.89432739 |
93 | Impaired social interactions (HP:0000735) | 1.87781706 |
94 | Abnormal social behavior (HP:0012433) | 1.87781706 |
95 | Dysmetria (HP:0001310) | 1.87626810 |
96 | Muscular dystrophy (HP:0003560) | 1.86572333 |
97 | Decreased motor nerve conduction velocity (HP:0003431) | 1.86249725 |
98 | Abnormal atrioventricular conduction (HP:0005150) | 1.85161193 |
99 | Absence seizures (HP:0002121) | 1.84104684 |
100 | Menstrual irregularities (HP:0000858) | 1.83536210 |
101 | Dysmetric saccades (HP:0000641) | 1.83043870 |
102 | Lipoatrophy (HP:0100578) | 1.82752177 |
103 | Truncal ataxia (HP:0002078) | 1.82468181 |
104 | Dilated cardiomyopathy (HP:0001644) | 1.82453427 |
105 | Depressed nasal tip (HP:0000437) | 1.82055911 |
106 | Obstructive sleep apnea (HP:0002870) | 1.81446710 |
107 | Genetic anticipation (HP:0003743) | 1.81436394 |
108 | Intention tremor (HP:0002080) | 1.81215056 |
109 | Anterior segment dysgenesis (HP:0007700) | 1.78587632 |
110 | Epileptic encephalopathy (HP:0200134) | 1.77460269 |
111 | Failure to thrive in infancy (HP:0001531) | 1.76457593 |
112 | Generalized tonic-clonic seizures (HP:0002069) | 1.76053905 |
113 | Absent speech (HP:0001344) | 1.74847417 |
114 | Abnormal EKG (HP:0003115) | 1.74701258 |
115 | Distal sensory impairment (HP:0002936) | 1.73577734 |
116 | Cerebral inclusion bodies (HP:0100314) | 1.73298304 |
117 | Scapular winging (HP:0003691) | 1.73284546 |
118 | Gowers sign (HP:0003391) | 1.72441441 |
119 | Round ear (HP:0100830) | 1.71668004 |
120 | Bradycardia (HP:0001662) | 1.71202347 |
121 | Excessive salivation (HP:0003781) | 1.69679640 |
122 | Drooling (HP:0002307) | 1.69679640 |
123 | Epileptiform EEG discharges (HP:0011182) | 1.69219168 |
124 | Narrow palate (HP:0000189) | 1.68850786 |
125 | Amyotrophic lateral sclerosis (HP:0007354) | 1.68632933 |
126 | Overgrowth (HP:0001548) | 1.68498043 |
127 | Hypercortisolism (HP:0001578) | 1.68440983 |
128 | Distal lower limb muscle weakness (HP:0009053) | 1.68205049 |
129 | Dysdiadochokinesis (HP:0002075) | 1.67998385 |
130 | Rapidly progressive (HP:0003678) | 1.67378101 |
131 | Poor eye contact (HP:0000817) | 1.67370662 |
132 | Increased circulating renin level (HP:0000848) | 1.67286632 |
133 | Abnormality of the ischium (HP:0003174) | 1.66452496 |
134 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.65903779 |
135 | Broad-based gait (HP:0002136) | 1.65237930 |
136 | Postural instability (HP:0002172) | 1.65153351 |
137 | Aqueductal stenosis (HP:0002410) | 1.63995637 |
138 | Papillary thyroid carcinoma (HP:0002895) | 1.62920398 |
139 | Pachygyria (HP:0001302) | 1.61551633 |
140 | Muscle stiffness (HP:0003552) | 1.61223322 |
141 | Gaze-evoked nystagmus (HP:0000640) | 1.60903691 |
Rank | Gene Set | Z-score |
---|---|---|
1 | LMTK2 | 2.85847305 |
2 | PHKG1 | 2.46526693 |
3 | PHKG2 | 2.46526693 |
4 | NTRK3 | 2.33141737 |
5 | MARK1 | 2.31180577 |
6 | STK39 | 2.27874931 |
7 | MAP3K9 | 2.26719100 |
8 | NTRK1 | 2.07208473 |
9 | CAMKK2 | 2.04271920 |
10 | WNK4 | 2.00855172 |
11 | KSR2 | 2.00303626 |
12 | LATS2 | 1.98191247 |
13 | MAP3K4 | 1.89960570 |
14 | PAK6 | 1.73421265 |
15 | RET | 1.64157221 |
16 | TTN | 1.62850500 |
17 | MINK1 | 1.60924092 |
18 | LATS1 | 1.60843313 |
19 | PDK3 | 1.51465631 |
20 | PDK4 | 1.51465631 |
21 | CAMK4 | 1.47835345 |
22 | PAK3 | 1.47195056 |
23 | WNK1 | 1.46192033 |
24 | AKT3 | 1.45671555 |
25 | MAP3K2 | 1.43019867 |
26 | DMPK | 1.41081816 |
27 | PRKD3 | 1.40598577 |
28 | EPHB1 | 1.39683695 |
29 | PIK3CG | 1.38035311 |
30 | CAMK1 | 1.35097230 |
31 | MAP2K4 | 1.30955154 |
32 | OXSR1 | 1.30032466 |
33 | EPHA4 | 1.29853788 |
34 | NTRK2 | 1.26370947 |
35 | FGFR2 | 1.25079153 |
36 | ERBB3 | 1.21126720 |
37 | STK38 | 1.19196683 |
38 | PNCK | 1.17985564 |
39 | MAP3K6 | 1.15878439 |
40 | SGK494 | 1.15865191 |
41 | SGK223 | 1.15865191 |
42 | FER | 1.13261185 |
43 | MAPK13 | 1.12471620 |
44 | TYRO3 | 1.10084103 |
45 | MAP2K7 | 1.09481614 |
46 | PDK2 | 1.05487427 |
47 | UHMK1 | 1.04754263 |
48 | PLK2 | 1.04692219 |
49 | OBSCN | 1.03068559 |
50 | FRK | 1.01438609 |
51 | PIK3CA | 1.00719085 |
52 | TXK | 0.98553425 |
53 | EPHA3 | 0.98374707 |
54 | CDK5 | 0.97337529 |
55 | GRK7 | 0.93762470 |
56 | SGK2 | 0.93759567 |
57 | PKN1 | 0.93198611 |
58 | RIPK1 | 0.92968331 |
59 | CAMK1G | 0.92669397 |
60 | NLK | 0.92659443 |
61 | PDGFRA | 0.92550465 |
62 | ROCK1 | 0.90433242 |
63 | GRK5 | 0.89645462 |
64 | SGK3 | 0.89504297 |
65 | PINK1 | 0.89378186 |
66 | TRIB3 | 0.88388638 |
67 | DAPK2 | 0.87682575 |
68 | PTK2B | 0.87316481 |
69 | PRKCH | 0.86338115 |
70 | STK38L | 0.83372372 |
71 | TRPM7 | 0.83295586 |
72 | TIE1 | 0.82213246 |
73 | TAOK3 | 0.82083208 |
74 | DYRK1B | 0.81822693 |
75 | MAP4K2 | 0.79953253 |
76 | MAP3K7 | 0.78541819 |
77 | KSR1 | 0.76795253 |
78 | CAMK2A | 0.76663700 |
79 | TAOK1 | 0.76351769 |
80 | FGFR3 | 0.75999007 |
81 | MUSK | 0.75382466 |
82 | PRKAA2 | 0.75148369 |
83 | MYLK | 0.73681357 |
84 | PRKCE | 0.72852480 |
85 | STK11 | 0.72676775 |
86 | CAMK1D | 0.72257505 |
87 | EPHB2 | 0.72196384 |
88 | CAMKK1 | 0.71137713 |
89 | MAP3K13 | 0.70702465 |
90 | MARK2 | 0.70428830 |
91 | PRKD1 | 0.70413303 |
92 | BCR | 0.69361989 |
93 | DYRK1A | 0.69262297 |
94 | STK24 | 0.68499674 |
95 | PDPK1 | 0.68253534 |
96 | MAP2K1 | 0.67265645 |
97 | ROCK2 | 0.66620110 |
98 | PTK2 | 0.66162737 |
99 | CSNK1G2 | 0.65659497 |
100 | CCNB1 | 0.65621741 |
101 | PDGFRB | 0.64913347 |
102 | CAMK2B | 0.63279590 |
103 | TNIK | 0.62912775 |
104 | PRKAA1 | 0.62680930 |
105 | INSRR | 0.62606453 |
106 | SGK1 | 0.61787014 |
107 | JAK1 | 0.61227358 |
108 | MAPK7 | 0.61014190 |
109 | PRKCG | 0.59604280 |
110 | FGFR4 | 0.59215675 |
111 | PRKG1 | 0.59197366 |
112 | NEK9 | 0.58498445 |
113 | PDK1 | 0.56792480 |
114 | MAP3K5 | 0.56093581 |
115 | CASK | 0.54288490 |
116 | LIMK1 | 0.54176628 |
117 | SIK1 | 0.54114497 |
118 | DDR2 | 0.54092458 |
119 | NEK6 | 0.53213064 |
120 | CDC42BPA | 0.52872752 |
121 | ICK | 0.51095451 |
122 | CAMK2D | 0.50811948 |
123 | MAP3K12 | 0.50207613 |
124 | WNK3 | 0.50030804 |
125 | MAPK12 | 0.49915183 |
126 | PRKCZ | 0.47680167 |
127 | ERBB4 | 0.47338666 |
128 | MAP3K1 | 0.46708782 |
129 | MOS | 0.46333936 |
130 | TGFBR2 | 0.45437173 |
131 | PRKCQ | 0.44180261 |
132 | BRD4 | 0.43525445 |
133 | MAPK10 | 0.42129837 |
134 | MAP3K3 | 0.40085043 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.75420235 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.71615238 |
3 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.63944314 |
4 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.57428477 |
5 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.52994135 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.52472209 |
7 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.52126880 |
8 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.45709130 |
9 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.42359051 |
10 | Circadian entrainment_Homo sapiens_hsa04713 | 1.41426848 |
11 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.40361233 |
12 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.38858647 |
13 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.36864871 |
14 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.36117198 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.34011648 |
16 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.33792317 |
17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.32579336 |
18 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.32212359 |
19 | Salivary secretion_Homo sapiens_hsa04970 | 1.31554483 |
20 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.29481408 |
21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.29185382 |
22 | Renin secretion_Homo sapiens_hsa04924 | 1.28449675 |
23 | Long-term potentiation_Homo sapiens_hsa04720 | 1.26244391 |
24 | Nicotine addiction_Homo sapiens_hsa05033 | 1.25705378 |
25 | Axon guidance_Homo sapiens_hsa04360 | 1.24599546 |
26 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.24436733 |
27 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.24203606 |
28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.23888567 |
29 | GABAergic synapse_Homo sapiens_hsa04727 | 1.22480218 |
30 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.21108908 |
31 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.17975570 |
32 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.16367439 |
33 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.15127447 |
34 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.13625021 |
35 | Insulin secretion_Homo sapiens_hsa04911 | 1.10786513 |
36 | Morphine addiction_Homo sapiens_hsa05032 | 1.10589521 |
37 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.09461464 |
38 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.09040443 |
39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.07989847 |
40 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.05652157 |
41 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.04639896 |
42 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.02556201 |
43 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.02447582 |
44 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.00955558 |
45 | Phototransduction_Homo sapiens_hsa04744 | 0.99183410 |
46 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.98632732 |
47 | Gap junction_Homo sapiens_hsa04540 | 0.96259910 |
48 | Taste transduction_Homo sapiens_hsa04742 | 0.95380822 |
49 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.94292662 |
50 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.93523825 |
51 | Bile secretion_Homo sapiens_hsa04976 | 0.92112132 |
52 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.91542333 |
53 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.90120942 |
54 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.89406939 |
55 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.89361445 |
56 | Long-term depression_Homo sapiens_hsa04730 | 0.88621000 |
57 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.87076497 |
58 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.86510249 |
59 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.85675147 |
60 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.84322204 |
61 | Glioma_Homo sapiens_hsa05214 | 0.84147177 |
62 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.82337042 |
63 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.81901437 |
64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81652316 |
65 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.81481287 |
66 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.80555800 |
67 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.79386283 |
68 | Cocaine addiction_Homo sapiens_hsa05030 | 0.78321496 |
69 | Focal adhesion_Homo sapiens_hsa04510 | 0.77943432 |
70 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.76858107 |
71 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.76494373 |
72 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.75816726 |
73 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.75216497 |
74 | Insulin resistance_Homo sapiens_hsa04931 | 0.75047766 |
75 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.73228608 |
76 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.72978971 |
77 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.71178550 |
78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71150411 |
79 | Melanogenesis_Homo sapiens_hsa04916 | 0.70722914 |
80 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.68905932 |
81 | Tight junction_Homo sapiens_hsa04530 | 0.68182995 |
82 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.67792058 |
83 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67729704 |
84 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.67483379 |
85 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.67108384 |
86 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.66999829 |
87 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.66979512 |
88 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.66125220 |
89 | Platelet activation_Homo sapiens_hsa04611 | 0.66026361 |
90 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.64784197 |
91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64612215 |
92 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.63508938 |
93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63199223 |
94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61436747 |
95 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.60814613 |
96 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.59640392 |
97 | Endometrial cancer_Homo sapiens_hsa05213 | 0.59340512 |
98 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.59260780 |
99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58963964 |
100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.57195093 |
101 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.56953188 |
102 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.55840988 |
103 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.54976735 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.54605668 |
105 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54408720 |
106 | Viral myocarditis_Homo sapiens_hsa05416 | 0.54299899 |
107 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53504248 |
108 | Adherens junction_Homo sapiens_hsa04520 | 0.53093755 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.51217923 |
110 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51087993 |
111 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.50866771 |
112 | Amoebiasis_Homo sapiens_hsa05146 | 0.49837231 |
113 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.49670698 |
114 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.49545584 |
115 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.49240061 |
116 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48759276 |
117 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.48505241 |
118 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.48349542 |
119 | Endocytosis_Homo sapiens_hsa04144 | 0.48107305 |
120 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47931229 |
121 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47754520 |
122 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45678467 |
123 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.43941817 |