CCT6P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chaperone-mediated protein transport (GO:0072321)4.72169269
2transcription elongation from RNA polymerase III promoter (GO:0006385)4.72150961
3termination of RNA polymerase III transcription (GO:0006386)4.72150961
4exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.45391804
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.45290697
6ATP synthesis coupled proton transport (GO:0015986)4.42833850
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.42833850
8nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.36376498
9cullin deneddylation (GO:0010388)4.24397702
10protein deneddylation (GO:0000338)4.23582512
11DNA deamination (GO:0045006)4.22232931
12protein complex biogenesis (GO:0070271)4.22155993
13proteasome assembly (GO:0043248)4.20209790
14inositol phosphate dephosphorylation (GO:0046855)4.16454522
15phosphorylated carbohydrate dephosphorylation (GO:0046838)4.16454522
16protein neddylation (GO:0045116)4.12885521
17inositol phosphate catabolic process (GO:0071545)4.10688740
18cytochrome complex assembly (GO:0017004)4.01223162
19establishment of protein localization to mitochondrial membrane (GO:0090151)3.98768288
20mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.96597352
21mitochondrial respiratory chain complex assembly (GO:0033108)3.84350254
22regulation of mitochondrial translation (GO:0070129)3.82949199
23organelle disassembly (GO:1903008)3.82334145
24respiratory chain complex IV assembly (GO:0008535)3.79993740
25mitochondrial respiratory chain complex I assembly (GO:0032981)3.78576265
26NADH dehydrogenase complex assembly (GO:0010257)3.78576265
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.78576265
28positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.77401862
29regulation of cilium movement (GO:0003352)3.77080124
30water-soluble vitamin biosynthetic process (GO:0042364)3.68527264
31electron transport chain (GO:0022900)3.67941305
32response to pheromone (GO:0019236)3.67935404
33respiratory electron transport chain (GO:0022904)3.64254011
34platelet dense granule organization (GO:0060155)3.46592611
35regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.42617471
36GTP biosynthetic process (GO:0006183)3.38670172
377-methylguanosine mRNA capping (GO:0006370)3.33090109
387-methylguanosine RNA capping (GO:0009452)3.24504950
39RNA capping (GO:0036260)3.24504950
40RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.23780751
41pseudouridine synthesis (GO:0001522)3.23497425
42behavioral response to nicotine (GO:0035095)3.23143745
43inner mitochondrial membrane organization (GO:0007007)3.19865370
44positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003573.19787099
45viral mRNA export from host cell nucleus (GO:0046784)3.16923974
46ribonucleoprotein complex disassembly (GO:0032988)3.15852817
47polyol catabolic process (GO:0046174)3.12160865
48replication fork processing (GO:0031297)3.11848269
49negative regulation of DNA-dependent DNA replication (GO:2000104)3.01671511
50hydrogen ion transmembrane transport (GO:1902600)3.01279583
51GPI anchor metabolic process (GO:0006505)2.99490353
52artery smooth muscle contraction (GO:0014824)2.92509827
53negative regulation of heart rate (GO:0010459)2.92154063
54DNA catabolic process, exonucleolytic (GO:0000738)2.92135109
55UTP biosynthetic process (GO:0006228)2.90836178
56transcription elongation from RNA polymerase I promoter (GO:0006362)2.89898187
57proton transport (GO:0015992)2.89653158
58pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.88283299
59DNA damage response, detection of DNA damage (GO:0042769)2.88163554
60hydrogen transport (GO:0006818)2.87117076
61DNA double-strand break processing (GO:0000729)2.84504589
62nonmotile primary cilium assembly (GO:0035058)2.83813263
63purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.81355622
64signal peptide processing (GO:0006465)2.80596193
65ribosome assembly (GO:0042255)2.75475591
66regulation of cellular respiration (GO:0043457)2.74880681
67protein targeting to mitochondrion (GO:0006626)2.73808683
68maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.73722009
69purine nucleoside triphosphate biosynthetic process (GO:0009145)2.73613549
70nucleotide transmembrane transport (GO:1901679)2.72963764
71negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.71143387
72pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.69655163
73pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.68632931
74UMP metabolic process (GO:0046049)2.68632931
75pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.68632931
76UMP biosynthetic process (GO:0006222)2.68632931
77maturation of 5.8S rRNA (GO:0000460)2.68178290
78protein localization to mitochondrion (GO:0070585)2.67636380
79regulation of cellular amino acid metabolic process (GO:0006521)2.66157009
80nucleoside diphosphate phosphorylation (GO:0006165)2.65949637
81negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.65717628
82positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.64789634
83transcription from RNA polymerase I promoter (GO:0006360)2.64446225
84ATP biosynthetic process (GO:0006754)2.63256291
85regulation of regulatory T cell differentiation (GO:0045589)2.61405545
86positive regulation of interleukin-17 production (GO:0032740)2.61230474
87regulation of microtubule-based movement (GO:0060632)2.60953839
88DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.60615740
89neuronal action potential propagation (GO:0019227)2.60293344
90DNA replication checkpoint (GO:0000076)2.60192475
91brain morphogenesis (GO:0048854)2.58613191
92termination of RNA polymerase I transcription (GO:0006363)2.56601281
93tRNA processing (GO:0008033)2.56458328
94regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.56226130
95UTP metabolic process (GO:0046051)2.55792547
96serotonin receptor signaling pathway (GO:0007210)2.55788975
97signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.55324358
98signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.55324358
99signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.55324358
100establishment of protein localization to mitochondrion (GO:0072655)2.53149498

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.21599373
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.14453565
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.66602769
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.23197578
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.13655957
6VDR_22108803_ChIP-Seq_LS180_Human3.00888202
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.96941601
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.79178631
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.60956105
10ELK1_19687146_ChIP-ChIP_HELA_Human2.56482959
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.52943341
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.49541220
13VDR_23849224_ChIP-Seq_CD4+_Human2.44841141
14ZNF274_21170338_ChIP-Seq_K562_Hela2.43772834
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.38229135
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.22342564
17EWS_26573619_Chip-Seq_HEK293_Human2.14745415
18FOXP3_21729870_ChIP-Seq_TREG_Human2.08808611
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.02175400
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.96313680
21CREB1_15753290_ChIP-ChIP_HEK293T_Human1.93853757
22PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91449086
23PCGF2_27294783_Chip-Seq_ESCs_Mouse1.87936728
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.86164338
25SRF_21415370_ChIP-Seq_HL-1_Mouse1.83099261
26FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.77892830
27IGF1R_20145208_ChIP-Seq_DFB_Human1.76822509
28SOX2_19829295_ChIP-Seq_ESCs_Human1.76290645
29NANOG_19829295_ChIP-Seq_ESCs_Human1.76290645
30POU3F2_20337985_ChIP-ChIP_501MEL_Human1.73663192
31NOTCH1_21737748_ChIP-Seq_TLL_Human1.72474847
32MYC_18555785_ChIP-Seq_MESCs_Mouse1.70475398
33P300_19829295_ChIP-Seq_ESCs_Human1.68203082
34PADI4_21655091_ChIP-ChIP_MCF-7_Human1.67296166
35MYC_18940864_ChIP-ChIP_HL60_Human1.66028970
36TAF15_26573619_Chip-Seq_HEK293_Human1.65363177
37PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.61950443
38CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.58745976
39FUS_26573619_Chip-Seq_HEK293_Human1.43796250
40MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43488382
41TP53_22573176_ChIP-Seq_HFKS_Human1.43394996
42ER_23166858_ChIP-Seq_MCF-7_Human1.42738768
43HTT_18923047_ChIP-ChIP_STHdh_Human1.40738478
44RBPJ_22232070_ChIP-Seq_NCS_Mouse1.38924297
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38917555
46CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37743518
47GABP_19822575_ChIP-Seq_HepG2_Human1.37041930
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36960704
49MYC_18358816_ChIP-ChIP_MESCs_Mouse1.35147997
50E2F4_17652178_ChIP-ChIP_JURKAT_Human1.34891816
51DCP1A_22483619_ChIP-Seq_HELA_Human1.32351355
52TTF2_22483619_ChIP-Seq_HELA_Human1.28074042
53MYC_19030024_ChIP-ChIP_MESCs_Mouse1.27666532
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26476392
55FOXA1_27270436_Chip-Seq_PROSTATE_Human1.24617442
56FOXA1_25329375_ChIP-Seq_VCAP_Human1.24617442
57SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.23750863
58AR_20517297_ChIP-Seq_VCAP_Human1.21461155
59SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21161809
60ELK1_22589737_ChIP-Seq_MCF10A_Human1.19245468
61GBX2_23144817_ChIP-Seq_PC3_Human1.14641340
62EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14447770
63HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.14387391
64NFE2_27457419_Chip-Seq_LIVER_Mouse1.12366475
65E2F1_18555785_ChIP-Seq_MESCs_Mouse1.10896678
66GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10134977
67STAT3_18555785_Chip-Seq_ESCs_Mouse1.09991648
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09358994
69NCOR_22424771_ChIP-Seq_293T_Human1.09114798
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.08485255
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.08138206
72UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08085660
73FOXA1_21572438_ChIP-Seq_LNCaP_Human1.06318792
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.05829885
75P53_22387025_ChIP-Seq_ESCs_Mouse1.05387236
76BCAT_22108803_ChIP-Seq_LS180_Human1.05262295
77EZH2_27294783_Chip-Seq_NPCs_Mouse1.04645493
78NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.03680553
79BMI1_23680149_ChIP-Seq_NPCS_Mouse1.03645900
80P300_18555785_Chip-Seq_ESCs_Mouse1.01133799
81EGR1_23403033_ChIP-Seq_LIVER_Mouse1.00237396
82PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99203968
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.99117189
84CBP_20019798_ChIP-Seq_JUKART_Human0.99117189
85TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97672559
86POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97346908
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95736608
88OCT4_18555785_Chip-Seq_ESCs_Mouse0.95358706
89CMYC_18555785_Chip-Seq_ESCs_Mouse0.94850002
90ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93712394
91YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.93470026
92MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93451151
93EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.93248349
94HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.93137951
95CRX_20693478_ChIP-Seq_RETINA_Mouse0.93119988
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92888162
97FOXH1_21741376_ChIP-Seq_EPCs_Human0.92505776
98TCF4_22108803_ChIP-Seq_LS180_Human0.92389974
99RUNX2_22187159_ChIP-Seq_PCA_Human0.91884993
100MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90905644

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair3.58451093
2MP0002102_abnormal_ear_morphology3.31904170
3MP0008877_abnormal_DNA_methylation3.23416039
4MP0003880_abnormal_central_pattern2.90874596
5MP0003195_calcinosis2.88126055
6MP0006072_abnormal_retinal_apoptosis2.84154493
7MP0000569_abnormal_digit_pigmentation2.82639417
8MP0001984_abnormal_olfaction2.68427797
9MP0003806_abnormal_nucleotide_metabolis2.67196155
10MP0005084_abnormal_gallbladder_morpholo2.36635121
11MP0010386_abnormal_urinary_bladder2.21395162
12MP0006276_abnormal_autonomic_nervous2.20527506
13MP0004147_increased_porphyrin_level2.18641866
14MP0003787_abnormal_imprinting2.16077611
15MP0005645_abnormal_hypothalamus_physiol1.98986401
16MP0008872_abnormal_physiological_respon1.96814297
17MP0001986_abnormal_taste_sensitivity1.92095050
18MP0005551_abnormal_eye_electrophysiolog1.89704230
19MP0003718_maternal_effect1.78505003
20MP0009046_muscle_twitch1.78282947
21MP0001968_abnormal_touch/_nociception1.75648861
22MP0003011_delayed_dark_adaptation1.75059747
23MP0003693_abnormal_embryo_hatching1.71452717
24MP0002254_reproductive_system_inflammat1.69931843
25MP0005379_endocrine/exocrine_gland_phen1.66297710
26MP0001905_abnormal_dopamine_level1.66183936
27MP0002837_dystrophic_cardiac_calcinosis1.65451108
28MP0004885_abnormal_endolymph1.59296229
29MP0000372_irregular_coat_pigmentation1.57042174
30MP0001529_abnormal_vocalization1.56735737
31MP0002876_abnormal_thyroid_physiology1.54711920
32MP0002234_abnormal_pharynx_morphology1.52679626
33MP0008875_abnormal_xenobiotic_pharmacok1.49138894
34MP0005389_reproductive_system_phenotype1.48578073
35MP0000631_abnormal_neuroendocrine_gland1.48534706
36MP0000427_abnormal_hair_cycle1.47138279
37MP0004142_abnormal_muscle_tone1.43099411
38MP0009697_abnormal_copulation1.42195609
39MP0001835_abnormal_antigen_presentation1.38883087
40MP0006292_abnormal_olfactory_placode1.38098677
41MP0002736_abnormal_nociception_after1.37684688
42MP0004742_abnormal_vestibular_system1.35908630
43MP0005410_abnormal_fertilization1.34533753
44MP0006035_abnormal_mitochondrial_morpho1.34329080
45MP0001919_abnormal_reproductive_system1.32413347
46MP0006036_abnormal_mitochondrial_physio1.29547207
47MP0005636_abnormal_mineral_homeostasis1.25197250
48MP0001485_abnormal_pinna_reflex1.24970608
49MP0005253_abnormal_eye_physiology1.22803460
50MP0002138_abnormal_hepatobiliary_system1.21028784
51MP0005075_abnormal_melanosome_morpholog1.19073437
52MP0002638_abnormal_pupillary_reflex1.17893482
53MP0001486_abnormal_startle_reflex1.17440807
54MP0002160_abnormal_reproductive_system1.15970826
55MP0010094_abnormal_chromosome_stability1.14147153
56MP0004145_abnormal_muscle_electrophysio1.11356742
57MP0005167_abnormal_blood-brain_barrier1.09839141
58MP0009745_abnormal_behavioral_response1.08348230
59MP0003786_premature_aging1.03651061
60MP0008789_abnormal_olfactory_epithelium1.02275181
61MP0002272_abnormal_nervous_system1.01607933
62MP0005310_abnormal_salivary_gland0.96488417
63MP0001188_hyperpigmentation0.95399287
64MP0003123_paternal_imprinting0.94879988
65MP0003121_genomic_imprinting0.91060132
66MP0001501_abnormal_sleep_pattern0.90143306
67MP0002090_abnormal_vision0.87946428
68MP0004084_abnormal_cardiac_muscle0.87131749
69MP0004019_abnormal_vitamin_homeostasis0.86878146
70MP0004215_abnormal_myocardial_fiber0.85957882
71MP0005646_abnormal_pituitary_gland0.85787799
72MP0003937_abnormal_limbs/digits/tail_de0.85531881
73MP0005332_abnormal_amino_acid0.85341206
74MP0003567_abnormal_fetal_cardiomyocyte0.82455910
75MP0002734_abnormal_mechanical_nocicepti0.82328126
76MP0004782_abnormal_surfactant_physiolog0.81591952
77MP0003646_muscle_fatigue0.80774152
78MP0004957_abnormal_blastocyst_morpholog0.79781743
79MP0009764_decreased_sensitivity_to0.77736384
80MP0004043_abnormal_pH_regulation0.76229526
81MP0004036_abnormal_muscle_relaxation0.75166096
82MP0001970_abnormal_pain_threshold0.74251391
83MP0004133_heterotaxia0.74105235
84MP0002938_white_spotting0.73211216
85MP0005174_abnormal_tail_pigmentation0.72858340
86MP0001929_abnormal_gametogenesis0.72630522
87MP0002735_abnormal_chemical_nociception0.72460643
88MP0008961_abnormal_basal_metabolism0.70238438
89MP0000465_gastrointestinal_hemorrhage0.68818766
90MP0000538_abnormal_urinary_bladder0.68195442
91MP0001764_abnormal_homeostasis0.66509281
92MP0003698_abnormal_male_reproductive0.65699057
93MP0002064_seizures0.65677058
94MP0005394_taste/olfaction_phenotype0.65669453
95MP0005499_abnormal_olfactory_system0.65669453
96MP0001293_anophthalmia0.65430212
97MP0005266_abnormal_metabolism0.64134132
98MP0000358_abnormal_cell_content/0.63129030
99MP0005647_abnormal_sex_gland0.63006558
100MP0002210_abnormal_sex_determination0.62682423

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.18750579
23-Methylglutaconic aciduria (HP:0003535)3.95681621
3Decreased activity of mitochondrial respiratory chain (HP:0008972)3.81692738
4Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.81692738
5Mitochondrial inheritance (HP:0001427)3.67625210
6Increased CSF lactate (HP:0002490)3.63645760
7Methylmalonic acidemia (HP:0002912)3.62162789
8Progressive macrocephaly (HP:0004481)3.61026922
9Acute encephalopathy (HP:0006846)3.52736738
10Abnormal mitochondria in muscle tissue (HP:0008316)3.45144753
11Septo-optic dysplasia (HP:0100842)3.36306621
12Lipid accumulation in hepatocytes (HP:0006561)3.14640385
13Increased hepatocellular lipid droplets (HP:0006565)3.00986090
14Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.94356783
15Hepatocellular necrosis (HP:0001404)2.92173579
16Abnormality of midbrain morphology (HP:0002418)2.84575307
17Molar tooth sign on MRI (HP:0002419)2.84575307
18Methylmalonic aciduria (HP:0012120)2.82661631
19Absent rod-and cone-mediated responses on ERG (HP:0007688)2.82487634
20Medial flaring of the eyebrow (HP:0010747)2.79576044
21Progressive inability to walk (HP:0002505)2.75938960
22Cerebral edema (HP:0002181)2.67328642
23Hepatic necrosis (HP:0002605)2.65852756
24Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.64857436
25Increased serum lactate (HP:0002151)2.63628336
26Unilateral renal agenesis (HP:0000122)2.60784527
27Lactic acidosis (HP:0003128)2.57429506
28Type I transferrin isoform profile (HP:0003642)2.56212687
29Agitation (HP:0000713)2.54755554
30Abnormality of the pons (HP:0007361)2.49327033
31Inability to walk (HP:0002540)2.45556386
32Abnormality of vitamin B metabolism (HP:0004340)2.35895855
33Microvesicular hepatic steatosis (HP:0001414)2.31201891
34Optic disc pallor (HP:0000543)2.29500443
35Abnormal protein glycosylation (HP:0012346)2.29367239
36Abnormal glycosylation (HP:0012345)2.29367239
37Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.29367239
38Abnormal protein N-linked glycosylation (HP:0012347)2.29367239
39Gait imbalance (HP:0002141)2.28456765
40Absent/shortened dynein arms (HP:0200106)2.24993518
41Dynein arm defect of respiratory motile cilia (HP:0012255)2.24993518
42Congenital primary aphakia (HP:0007707)2.22235609
43Adrenal hypoplasia (HP:0000835)2.21260100
44Pendular nystagmus (HP:0012043)2.19057795
45Abnormal respiratory motile cilium morphology (HP:0005938)2.18125454
46Abnormal respiratory epithelium morphology (HP:0012253)2.18125454
47Abolished electroretinogram (ERG) (HP:0000550)2.17960368
48Absent septum pellucidum (HP:0001331)2.17537081
49Constricted visual fields (HP:0001133)2.15568847
50Congenital, generalized hypertrichosis (HP:0004540)2.15329386
51Pancreatic cysts (HP:0001737)2.12325783
52Abnormal sex determination (HP:0012244)2.09769773
53Sex reversal (HP:0012245)2.09769773
54Hypoproteinemia (HP:0003075)2.09218939
55Hypomagnesemia (HP:0002917)2.07454913
56Lethargy (HP:0001254)2.06774193
57Abnormality of the vitamin B12 metabolism (HP:0004341)2.04858607
58True hermaphroditism (HP:0010459)2.04633825
59Nephrogenic diabetes insipidus (HP:0009806)2.00736825
60Focal motor seizures (HP:0011153)1.99095956
61Pancreatic fibrosis (HP:0100732)1.98793970
62Abnormality of the prostate (HP:0008775)1.98564688
63Cerebral hypomyelination (HP:0006808)1.97675626
64Decreased electroretinogram (ERG) amplitude (HP:0000654)1.97478042
65Renal Fanconi syndrome (HP:0001994)1.97239757
66Keratoconus (HP:0000563)1.96624457
67Increased corneal curvature (HP:0100692)1.96624457
68Global brain atrophy (HP:0002283)1.94940634
69Respiratory failure (HP:0002878)1.94892247
70Nephronophthisis (HP:0000090)1.91180994
71Abnormal biliary tract physiology (HP:0012439)1.90762734
72Bile duct proliferation (HP:0001408)1.90762734
73Leukodystrophy (HP:0002415)1.90728870
74Hypoplasia of the pons (HP:0012110)1.90214334
75Large for gestational age (HP:0001520)1.90144453
76Abnormal number of erythroid precursors (HP:0012131)1.88854403
77Congenital stationary night blindness (HP:0007642)1.87415622
78Overlapping toe (HP:0001845)1.86928434
79Abnormal rod and cone electroretinograms (HP:0008323)1.86270474
80Prolonged neonatal jaundice (HP:0006579)1.86094198
81Exertional dyspnea (HP:0002875)1.85213473
82Abnormality of dental color (HP:0011073)1.82756205
83Abnormality of dicarboxylic acid metabolism (HP:0010995)1.82088312
84Dicarboxylic aciduria (HP:0003215)1.82088312
85Exercise intolerance (HP:0003546)1.82044541
86Abnormality of the anterior horn cell (HP:0006802)1.80940870
87Degeneration of anterior horn cells (HP:0002398)1.80940870
88Aplasia/hypoplasia of the uterus (HP:0008684)1.80456336
89Increased intramyocellular lipid droplets (HP:0012240)1.80327239
90Parakeratosis (HP:0001036)1.79603493
91Abnormal ciliary motility (HP:0012262)1.79577228
92Reduced antithrombin III activity (HP:0001976)1.78712862
93Restlessness (HP:0000711)1.77556466
94Increased serum pyruvate (HP:0003542)1.77347430
95Muscular hypotonia of the trunk (HP:0008936)1.76314176
96Male pseudohermaphroditism (HP:0000037)1.75374281
97Aplastic anemia (HP:0001915)1.75059950
98Renal salt wasting (HP:0000127)1.72348278
99Intestinal atresia (HP:0011100)1.71443941
100Abnormal respiratory motile cilium physiology (HP:0012261)1.71422629

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK2.75164799
2MST42.67929300
3TIE12.63942103
4PINK12.59919005
5WNK32.44686897
6TRIM282.41275963
7EIF2AK32.41210375
8ZAK2.29682495
9BRSK22.21953603
10GRK12.21401023
11OXSR12.03411783
12SRPK12.01843596
13MAP4K21.88925156
14STK391.86106440
15NUAK11.84568605
16TXK1.77743806
17CDK81.77509783
18PLK31.77278045
19CAMKK21.77091180
20PHKG21.72719406
21PHKG11.72719406
22DYRK21.70064020
23VRK21.69224566
24CSNK1G31.64858687
25BMPR1B1.64682037
26TEC1.64258005
27CSNK1A1L1.62770220
28VRK11.62066035
29TLK11.55952706
30ADRBK21.53764584
31BCKDK1.51783314
32MAP3K41.50658292
33CSNK1G21.47334071
34EIF2AK11.46987142
35BCR1.46470726
36BUB11.42249728
37MKNK11.40901668
38MAP2K71.39652114
39WNK41.36153615
40MKNK21.34810586
41CSNK1G11.33128624
42TSSK61.32302439
43NEK11.31010564
44MAP3K121.22901375
45CDK191.22624265
46INSRR1.21331648
47FGFR21.07045926
48PLK41.04336076
49PBK0.98437533
50PRKCE0.96712670
51MINK10.94839666
52PAK30.92055572
53RPS6KA40.91269265
54PLK20.89983062
55MAPK130.86486553
56EIF2AK20.78895393
57BRSK10.75528168
58RPS6KA50.74320029
59PLK10.73567686
60STK30.66396408
61KIT0.65067778
62STK38L0.64343318
63ALK0.63527564
64DAPK20.59362743
65ERBB30.58843810
66CHEK20.55764381
67ACVR1B0.55218071
68CSNK2A20.53176335
69PRKCI0.53117613
70TNIK0.52552780
71CASK0.52047440
72RPS6KB20.51680055
73PRKCG0.51219052
74MAP3K140.51092812
75ITK0.49517086
76WEE10.48734120
77CSNK1A10.48548273
78TAF10.46451079
79IGF1R0.43253055
80TTK0.39675123
81PRKACA0.39251061
82YES10.38818092
83EGFR0.38623828
84CSNK2A10.37543055
85CAMK2A0.37436324
86MATK0.37331520
87ATR0.36572724
88PRKG10.33571625
89PRKCA0.32595763
90DYRK30.32381661
91ABL10.32303501
92TGFBR10.31639252
93PRKCQ0.29981344
94ATM0.29952002
95LYN0.28070742
96FES0.28011932
97PRKG20.27466514
98MYLK0.27187137
99ADRBK10.26929521
100GRK50.26682852

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.86105491
2Oxidative phosphorylation_Homo sapiens_hsa001903.80687884
3Proteasome_Homo sapiens_hsa030503.56732621
4RNA polymerase_Homo sapiens_hsa030203.35156349
5Parkinsons disease_Homo sapiens_hsa050122.95002482
6Sulfur metabolism_Homo sapiens_hsa009202.49910953
7Ribosome_Homo sapiens_hsa030102.19427605
8Basal transcription factors_Homo sapiens_hsa030222.17134328
9Asthma_Homo sapiens_hsa053102.08684658
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.02545208
11Huntingtons disease_Homo sapiens_hsa050162.00196636
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.99992990
13Alzheimers disease_Homo sapiens_hsa050101.91751429
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.87135577
15Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.81050021
16Pyrimidine metabolism_Homo sapiens_hsa002401.73592798
17Cardiac muscle contraction_Homo sapiens_hsa042601.70877546
18Phototransduction_Homo sapiens_hsa047441.66638899
19Collecting duct acid secretion_Homo sapiens_hsa049661.62005871
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.60878055
21Type I diabetes mellitus_Homo sapiens_hsa049401.60582497
22RNA degradation_Homo sapiens_hsa030181.58680310
23Propanoate metabolism_Homo sapiens_hsa006401.55467067
24Homologous recombination_Homo sapiens_hsa034401.51331803
25Folate biosynthesis_Homo sapiens_hsa007901.45349809
26Allograft rejection_Homo sapiens_hsa053301.43848479
27RNA transport_Homo sapiens_hsa030131.42628872
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41164503
29Intestinal immune network for IgA production_Homo sapiens_hsa046721.38465376
30Autoimmune thyroid disease_Homo sapiens_hsa053201.33056528
31Graft-versus-host disease_Homo sapiens_hsa053321.29022129
32Non-homologous end-joining_Homo sapiens_hsa034501.28723111
33Nucleotide excision repair_Homo sapiens_hsa034201.28049791
34Fanconi anemia pathway_Homo sapiens_hsa034601.20100325
35Base excision repair_Homo sapiens_hsa034101.19972273
36Linoleic acid metabolism_Homo sapiens_hsa005911.19646079
37Purine metabolism_Homo sapiens_hsa002301.14660120
38Spliceosome_Homo sapiens_hsa030401.14293437
39One carbon pool by folate_Homo sapiens_hsa006701.11814462
40Caffeine metabolism_Homo sapiens_hsa002321.11248717
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.09874111
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08208639
43DNA replication_Homo sapiens_hsa030301.05693164
44Rheumatoid arthritis_Homo sapiens_hsa053231.05605300
45Fatty acid elongation_Homo sapiens_hsa000621.04904571
46Regulation of autophagy_Homo sapiens_hsa041401.04411521
47Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.02653913
48Drug metabolism - other enzymes_Homo sapiens_hsa009831.00269216
49Nitrogen metabolism_Homo sapiens_hsa009100.97761008
50Pyruvate metabolism_Homo sapiens_hsa006200.92408919
51Peroxisome_Homo sapiens_hsa041460.91879816
52Maturity onset diabetes of the young_Homo sapiens_hsa049500.91666635
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.90775465
54Primary bile acid biosynthesis_Homo sapiens_hsa001200.88005344
55Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.87369776
56Mismatch repair_Homo sapiens_hsa034300.77075161
57Selenocompound metabolism_Homo sapiens_hsa004500.75464666
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.73927541
59Steroid biosynthesis_Homo sapiens_hsa001000.73874430
60Metabolic pathways_Homo sapiens_hsa011000.73123655
61Butanoate metabolism_Homo sapiens_hsa006500.70928150
62Ether lipid metabolism_Homo sapiens_hsa005650.69113667
63Tryptophan metabolism_Homo sapiens_hsa003800.67395361
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.66612565
65beta-Alanine metabolism_Homo sapiens_hsa004100.63887893
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63708889
67Vibrio cholerae infection_Homo sapiens_hsa051100.61698801
68Retinol metabolism_Homo sapiens_hsa008300.58743371
69Olfactory transduction_Homo sapiens_hsa047400.57626018
70Glutathione metabolism_Homo sapiens_hsa004800.57529087
71Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.57382715
72Glycerolipid metabolism_Homo sapiens_hsa005610.56298459
73Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.55831874
74Arachidonic acid metabolism_Homo sapiens_hsa005900.51813304
75Chemical carcinogenesis_Homo sapiens_hsa052040.49801724
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48478235
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45498074
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45468459
79Nicotine addiction_Homo sapiens_hsa050330.45375486
80Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41533883
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38916731
82Fatty acid metabolism_Homo sapiens_hsa012120.38512027
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38180602
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.37791715
85Antigen processing and presentation_Homo sapiens_hsa046120.37591725
86Morphine addiction_Homo sapiens_hsa050320.37347536
87Fat digestion and absorption_Homo sapiens_hsa049750.35365071
88Sulfur relay system_Homo sapiens_hsa041220.35018381
89Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.33449595
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32005522
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31666877
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.31480533
93Fatty acid degradation_Homo sapiens_hsa000710.30857099
94Serotonergic synapse_Homo sapiens_hsa047260.30174986
95Vitamin digestion and absorption_Homo sapiens_hsa049770.28017192
96Vitamin B6 metabolism_Homo sapiens_hsa007500.27921500
97p53 signaling pathway_Homo sapiens_hsa041150.27903108
98Salivary secretion_Homo sapiens_hsa049700.27695509
99Epstein-Barr virus infection_Homo sapiens_hsa051690.26743523
100mRNA surveillance pathway_Homo sapiens_hsa030150.26406169

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »