

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of dendrite morphogenesis (GO:0050774) | 9.95213254 |
| 2 | Rap protein signal transduction (GO:0032486) | 8.97450780 |
| 3 | protein K11-linked deubiquitination (GO:0035871) | 6.52896512 |
| 4 | keratinocyte development (GO:0003334) | 6.16430963 |
| 5 | positive regulation of protein autophosphorylation (GO:0031954) | 5.98380949 |
| 6 | negative regulation of dendrite development (GO:2000171) | 5.80961964 |
| 7 | lactate metabolic process (GO:0006089) | 5.60747318 |
| 8 | pseudouridine synthesis (GO:0001522) | 5.42963274 |
| 9 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 5.34651608 |
| 10 | regulation of RIG-I signaling pathway (GO:0039535) | 5.31165283 |
| 11 | negative regulation of neurological system process (GO:0031645) | 5.22661866 |
| 12 | single strand break repair (GO:0000012) | 5.18227924 |
| 13 | amine catabolic process (GO:0009310) | 4.87716959 |
| 14 | cellular biogenic amine catabolic process (GO:0042402) | 4.87716959 |
| 15 | polyamine biosynthetic process (GO:0006596) | 4.86595324 |
| 16 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 4.79068137 |
| 17 | otic vesicle formation (GO:0030916) | 4.73827406 |
| 18 | negative regulation of JUN kinase activity (GO:0043508) | 4.45116219 |
| 19 | trophectodermal cell differentiation (GO:0001829) | 4.43348305 |
| 20 | inositol phosphate-mediated signaling (GO:0048016) | 4.26203270 |
| 21 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 4.21288010 |
| 22 | nephron tubule formation (GO:0072079) | 4.19043446 |
| 23 | chemosensory behavior (GO:0007635) | 4.11113522 |
| 24 | cellular biogenic amine biosynthetic process (GO:0042401) | 4.07760969 |
| 25 | negative regulation of bone resorption (GO:0045779) | 4.07666978 |
| 26 | negative regulation of epithelial to mesenchymal transition (GO:0010719) | 3.99874902 |
| 27 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.96316313 |
| 28 | amine biosynthetic process (GO:0009309) | 3.92286948 |
| 29 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.90880005 |
| 30 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.90880005 |
| 31 | heart valve morphogenesis (GO:0003179) | 3.89322569 |
| 32 | G-protein coupled receptor internalization (GO:0002031) | 3.85184373 |
| 33 | phasic smooth muscle contraction (GO:0014821) | 3.77370170 |
| 34 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.76924079 |
| 35 | pyrimidine dimer repair (GO:0006290) | 3.75945500 |
| 36 | ER overload response (GO:0006983) | 3.72826137 |
| 37 | artery smooth muscle contraction (GO:0014824) | 3.65228494 |
| 38 | regulation of relaxation of muscle (GO:1901077) | 3.63111865 |
| 39 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 3.60245950 |
| 40 | limb bud formation (GO:0060174) | 3.56852296 |
| 41 | protein K48-linked deubiquitination (GO:0071108) | 3.54544640 |
| 42 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.52132989 |
| 43 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 3.50621158 |
| 44 | eye photoreceptor cell differentiation (GO:0001754) | 3.45490448 |
| 45 | photoreceptor cell differentiation (GO:0046530) | 3.45490448 |
| 46 | DNA double-strand break processing (GO:0000729) | 3.44565976 |
| 47 | positive regulation of male gonad development (GO:2000020) | 3.43933262 |
| 48 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 3.37350874 |
| 49 | positive regulation of cell size (GO:0045793) | 3.30311804 |
| 50 | regulation of protein autophosphorylation (GO:0031952) | 3.27359406 |
| 51 | ovulation from ovarian follicle (GO:0001542) | 3.23026010 |
| 52 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.20401285 |
| 53 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.18689708 |
| 54 | negative regulation of myoblast differentiation (GO:0045662) | 3.17570213 |
| 55 | regulation of helicase activity (GO:0051095) | 3.15168626 |
| 56 | negative regulation of bone remodeling (GO:0046851) | 3.15003099 |
| 57 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 3.12462125 |
| 58 | S-adenosylmethionine metabolic process (GO:0046500) | 3.12331661 |
| 59 | polyamine metabolic process (GO:0006595) | 3.12317635 |
| 60 | regulation of male gonad development (GO:2000018) | 3.11468655 |
| 61 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 3.07986207 |
| 62 | NIK/NF-kappaB signaling (GO:0038061) | 3.07969156 |
| 63 | cardiac epithelial to mesenchymal transition (GO:0060317) | 3.07313940 |
| 64 | DNA deamination (GO:0045006) | 3.06386101 |
| 65 | tonic smooth muscle contraction (GO:0014820) | 3.06161239 |
| 66 | positive regulation of extracellular matrix organization (GO:1903055) | 2.99863479 |
| 67 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.99572860 |
| 68 | negative regulation of stem cell differentiation (GO:2000737) | 2.91982733 |
| 69 | notochord development (GO:0030903) | 2.90755972 |
| 70 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.89756437 |
| 71 | negative regulation of smooth muscle contraction (GO:0045986) | 2.88999742 |
| 72 | piRNA metabolic process (GO:0034587) | 2.82628549 |
| 73 | proteasome assembly (GO:0043248) | 2.82303312 |
| 74 | DNA damage response, detection of DNA damage (GO:0042769) | 2.80021822 |
| 75 | myoblast migration (GO:0051451) | 2.78575414 |
| 76 | negative regulation of tissue remodeling (GO:0034104) | 2.76120843 |
| 77 | rRNA methylation (GO:0031167) | 2.73650286 |
| 78 | peristalsis (GO:0030432) | 2.73126015 |
| 79 | regulation of hexokinase activity (GO:1903299) | 2.72732178 |
| 80 | regulation of glucokinase activity (GO:0033131) | 2.72732178 |
| 81 | cAMP catabolic process (GO:0006198) | 2.71769110 |
| 82 | protein K63-linked deubiquitination (GO:0070536) | 2.71726878 |
| 83 | positive regulation of cytokinesis (GO:0032467) | 2.71237094 |
| 84 | endothelial cell proliferation (GO:0001935) | 2.71135902 |
| 85 | protein localization to microtubule (GO:0035372) | 2.70792769 |
| 86 | regulation of cardioblast differentiation (GO:0051890) | 2.70182977 |
| 87 | neural crest cell development (GO:0014032) | 2.69143487 |
| 88 | positive regulation of histone methylation (GO:0031062) | 2.68885990 |
| 89 | protein maturation by protein folding (GO:0022417) | 2.67959098 |
| 90 | positive regulation of macrophage differentiation (GO:0045651) | 2.66937894 |
| 91 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 2.66633547 |
| 92 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 2.66269349 |
| 93 | male sex determination (GO:0030238) | 2.63576513 |
| 94 | detection of temperature stimulus (GO:0016048) | 2.63546476 |
| 95 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 2.63181248 |
| 96 | interferon-gamma production (GO:0032609) | 2.62068399 |
| 97 | cytokine biosynthetic process (GO:0042089) | 2.59375094 |
| 98 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 2.57849501 |
| 99 | regulation of memory T cell differentiation (GO:0043380) | 2.56992477 |
| 100 | sensory perception of smell (GO:0007608) | 2.55791496 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 3.73151726 |
| 2 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 3.71609133 |
| 3 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.21166144 |
| 4 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.20692877 |
| 5 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 3.10223286 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.96173230 |
| 7 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.70048642 |
| 8 | FUS_26573619_Chip-Seq_HEK293_Human | 2.63245308 |
| 9 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 2.51759578 |
| 10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.49525083 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.46678982 |
| 12 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 2.34044281 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.21471533 |
| 14 | CJUN_26792858_Chip-Seq_BT549_Human | 2.13695218 |
| 15 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.10305814 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.02983139 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94124344 |
| 18 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.93338903 |
| 19 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.84130582 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 1.83772177 |
| 21 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.70571354 |
| 22 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.68698699 |
| 23 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.68184982 |
| 24 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.67776444 |
| 25 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.65041088 |
| 26 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.62170840 |
| 27 | RXR_22108803_ChIP-Seq_LS180_Human | 1.60660028 |
| 28 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.60374249 |
| 29 | P300_19829295_ChIP-Seq_ESCs_Human | 1.60351684 |
| 30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.60084801 |
| 31 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.56136730 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.54444928 |
| 33 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.54155574 |
| 34 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.54113393 |
| 35 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.54037642 |
| 36 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.53262755 |
| 37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.53043349 |
| 38 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.52803110 |
| 39 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.51503386 |
| 40 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.48601521 |
| 41 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.47881470 |
| 42 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.47425041 |
| 43 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.46081915 |
| 44 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.46049590 |
| 45 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.45858452 |
| 46 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.44315733 |
| 47 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.44092295 |
| 48 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.43814989 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.41857010 |
| 50 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.40657469 |
| 51 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.40014759 |
| 52 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.40014759 |
| 53 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.38402800 |
| 54 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.37614570 |
| 55 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.37515627 |
| 56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.37286735 |
| 57 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35160779 |
| 58 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.33389830 |
| 59 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.33063556 |
| 60 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.29313814 |
| 61 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.27896705 |
| 62 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.27628370 |
| 63 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27455994 |
| 64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.26859255 |
| 65 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.26282950 |
| 66 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.25296837 |
| 67 | TBL1_22424771_ChIP-Seq_293T_Human | 1.25073501 |
| 68 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.24661215 |
| 69 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.24398486 |
| 70 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.24178433 |
| 71 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.23546980 |
| 72 | NFYB_21822215_ChIP-Seq_K562_Human | 1.23541860 |
| 73 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22802080 |
| 74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.22509221 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.22509221 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.22404496 |
| 77 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.19870069 |
| 78 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.19083555 |
| 79 | GATA1_22025678_ChIP-Seq_K562_Human | 1.18547710 |
| 80 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.18122297 |
| 81 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17835575 |
| 82 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.17051184 |
| 83 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.14386975 |
| 84 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.13701856 |
| 85 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.13701856 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.12572085 |
| 87 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.12430550 |
| 88 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.11936223 |
| 89 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.11414610 |
| 90 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.11283484 |
| 91 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.10008672 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09325710 |
| 93 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.09234685 |
| 94 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.09196906 |
| 95 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.06348741 |
| 96 | CBP_21632823_ChIP-Seq_H3396_Human | 1.05909007 |
| 97 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.05303714 |
| 98 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.04924867 |
| 99 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.02429216 |
| 100 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.02045403 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005670_abnormal_white_adipose | 7.16809415 |
| 2 | MP0008057_abnormal_DNA_replication | 5.13386384 |
| 3 | MP0000569_abnormal_digit_pigmentation | 3.32156055 |
| 4 | MP0006276_abnormal_autonomic_nervous | 2.98570808 |
| 5 | MP0008007_abnormal_cellular_replicative | 2.46903047 |
| 6 | MP0008058_abnormal_DNA_repair | 2.39378217 |
| 7 | MP0005167_abnormal_blood-brain_barrier | 2.33980013 |
| 8 | MP0001873_stomach_inflammation | 2.19293117 |
| 9 | MP0002735_abnormal_chemical_nociception | 2.17783246 |
| 10 | MP0001853_heart_inflammation | 2.10606724 |
| 11 | MP0003123_paternal_imprinting | 2.09225986 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 2.07595559 |
| 13 | MP0003718_maternal_effect | 1.97608590 |
| 14 | MP0002282_abnormal_trachea_morphology | 1.93319603 |
| 15 | MP0006036_abnormal_mitochondrial_physio | 1.85498900 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.81232889 |
| 17 | MP0001542_abnormal_bone_strength | 1.78901924 |
| 18 | MP0002909_abnormal_adrenal_gland | 1.78144252 |
| 19 | MP0001765_abnormal_ion_homeostasis | 1.71823704 |
| 20 | MP0000613_abnormal_salivary_gland | 1.68818513 |
| 21 | MP0001529_abnormal_vocalization | 1.65506130 |
| 22 | MP0008872_abnormal_physiological_respon | 1.64241489 |
| 23 | MP0005174_abnormal_tail_pigmentation | 1.63722311 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.62416064 |
| 25 | MP0001485_abnormal_pinna_reflex | 1.57335638 |
| 26 | MP0002638_abnormal_pupillary_reflex | 1.56681038 |
| 27 | MP0009840_abnormal_foam_cell | 1.50499449 |
| 28 | MP0005636_abnormal_mineral_homeostasis | 1.47598977 |
| 29 | MP0003786_premature_aging | 1.47450144 |
| 30 | MP0003567_abnormal_fetal_cardiomyocyte | 1.46307660 |
| 31 | MP0004019_abnormal_vitamin_homeostasis | 1.44655318 |
| 32 | MP0002234_abnormal_pharynx_morphology | 1.42674928 |
| 33 | MP0003724_increased_susceptibility_to | 1.39064766 |
| 34 | MP0005671_abnormal_response_to | 1.38394616 |
| 35 | MP0003693_abnormal_embryo_hatching | 1.36363732 |
| 36 | MP0006072_abnormal_retinal_apoptosis | 1.34127685 |
| 37 | MP0005395_other_phenotype | 1.29857374 |
| 38 | MP0002148_abnormal_hypersensitivity_rea | 1.28228457 |
| 39 | MP0009046_muscle_twitch | 1.26327802 |
| 40 | MP0005075_abnormal_melanosome_morpholog | 1.22936530 |
| 41 | MP0002233_abnormal_nose_morphology | 1.22710088 |
| 42 | MP0006138_congestive_heart_failure | 1.22377569 |
| 43 | MP0001501_abnormal_sleep_pattern | 1.21875392 |
| 44 | MP0000372_irregular_coat_pigmentation | 1.20977475 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 1.20030249 |
| 46 | MP0003195_calcinosis | 1.19510039 |
| 47 | MP0005410_abnormal_fertilization | 1.12084501 |
| 48 | MP0000015_abnormal_ear_pigmentation | 1.09977859 |
| 49 | MP0005083_abnormal_biliary_tract | 1.09793833 |
| 50 | MP0002693_abnormal_pancreas_physiology | 1.09738703 |
| 51 | MP0004147_increased_porphyrin_level | 1.08017799 |
| 52 | MP0002166_altered_tumor_susceptibility | 1.04698737 |
| 53 | MP0008995_early_reproductive_senescence | 1.03730672 |
| 54 | MP0003828_pulmonary_edema | 1.03606102 |
| 55 | MP0009643_abnormal_urine_homeostasis | 1.01634803 |
| 56 | MP0004484_altered_response_of | 1.01271354 |
| 57 | MP0000537_abnormal_urethra_morphology | 0.99422299 |
| 58 | MP0008875_abnormal_xenobiotic_pharmacok | 0.96420063 |
| 59 | MP0004782_abnormal_surfactant_physiolog | 0.95726561 |
| 60 | MP0004264_abnormal_extraembryonic_tissu | 0.95293947 |
| 61 | MP0003943_abnormal_hepatobiliary_system | 0.94851637 |
| 62 | MP0002972_abnormal_cardiac_muscle | 0.94227215 |
| 63 | MP0002168_other_aberrant_phenotype | 0.93169418 |
| 64 | MP0005332_abnormal_amino_acid | 0.92280471 |
| 65 | MP0000538_abnormal_urinary_bladder | 0.90684167 |
| 66 | MP0005647_abnormal_sex_gland | 0.89945235 |
| 67 | MP0003303_peritoneal_inflammation | 0.89494624 |
| 68 | MP0005551_abnormal_eye_electrophysiolog | 0.87533883 |
| 69 | MP0005620_abnormal_muscle_contractility | 0.87172118 |
| 70 | MP0003950_abnormal_plasma_membrane | 0.84584524 |
| 71 | MP0005379_endocrine/exocrine_gland_phen | 0.84497649 |
| 72 | MP0004270_analgesia | 0.83741702 |
| 73 | MP0001727_abnormal_embryo_implantation | 0.83547848 |
| 74 | MP0001666_abnormal_nutrient_absorption | 0.83031363 |
| 75 | MP0003045_fibrosis | 0.81314031 |
| 76 | MP0009764_decreased_sensitivity_to | 0.81119447 |
| 77 | MP0001944_abnormal_pancreas_morphology | 0.80040129 |
| 78 | MP0009278_abnormal_bone_marrow | 0.79755381 |
| 79 | MP0010352_gastrointestinal_tract_polyps | 0.79142914 |
| 80 | MP0001800_abnormal_humoral_immune | 0.77130992 |
| 81 | MP0003866_abnormal_defecation | 0.76983960 |
| 82 | MP0002254_reproductive_system_inflammat | 0.76880203 |
| 83 | MP0000049_abnormal_middle_ear | 0.76414345 |
| 84 | MP0000013_abnormal_adipose_tissue | 0.74712422 |
| 85 | MP0005253_abnormal_eye_physiology | 0.74597033 |
| 86 | MP0002006_tumorigenesis | 0.73012983 |
| 87 | MP0002102_abnormal_ear_morphology | 0.70799723 |
| 88 | MP0005000_abnormal_immune_tolerance | 0.70221123 |
| 89 | MP0002796_impaired_skin_barrier | 0.69585368 |
| 90 | MP0005084_abnormal_gallbladder_morpholo | 0.69260600 |
| 91 | MP0002277_abnormal_respiratory_mucosa | 0.69095989 |
| 92 | MP0002295_abnormal_pulmonary_circulatio | 0.68314276 |
| 93 | MP0000230_abnormal_systemic_arterial | 0.67652775 |
| 94 | MP0004085_abnormal_heartbeat | 0.67540712 |
| 95 | MP0002132_abnormal_respiratory_system | 0.67114754 |
| 96 | MP0003936_abnormal_reproductive_system | 0.65363930 |
| 97 | MP0005397_hematopoietic_system_phenotyp | 0.65326082 |
| 98 | MP0001545_abnormal_hematopoietic_system | 0.65326082 |
| 99 | MP0000639_abnormal_adrenal_gland | 0.63876533 |
| 100 | MP0002249_abnormal_larynx_morphology | 0.63509693 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Alopecia of scalp (HP:0002293) | 6.01942363 |
| 2 | Follicular hyperkeratosis (HP:0007502) | 5.57036987 |
| 3 | True hermaphroditism (HP:0010459) | 5.15700883 |
| 4 | 11 pairs of ribs (HP:0000878) | 4.95913232 |
| 5 | Abnormal sex determination (HP:0012244) | 4.79885422 |
| 6 | Sex reversal (HP:0012245) | 4.79885422 |
| 7 | Congenital stationary night blindness (HP:0007642) | 4.16370571 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 3.86932786 |
| 9 | Abnormality of midbrain morphology (HP:0002418) | 3.86932786 |
| 10 | Sensory axonal neuropathy (HP:0003390) | 3.72816101 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.51469541 |
| 12 | Abnormal biliary tract physiology (HP:0012439) | 3.50092691 |
| 13 | Bile duct proliferation (HP:0001408) | 3.50092691 |
| 14 | Abnormality of dental color (HP:0011073) | 3.49203327 |
| 15 | Nephronophthisis (HP:0000090) | 3.44220967 |
| 16 | Genetic anticipation (HP:0003743) | 3.42926999 |
| 17 | Duplicated collecting system (HP:0000081) | 3.37916392 |
| 18 | Impaired smooth pursuit (HP:0007772) | 3.33409442 |
| 19 | Vacuolated lymphocytes (HP:0001922) | 3.32557337 |
| 20 | Atonic seizures (HP:0010819) | 3.27567295 |
| 21 | Abnormality of the renal collecting system (HP:0004742) | 3.25211301 |
| 22 | Ureteral duplication (HP:0000073) | 3.16699467 |
| 23 | Pancreatic cysts (HP:0001737) | 3.06719732 |
| 24 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.05572002 |
| 25 | Sparse eyelashes (HP:0000653) | 2.96924850 |
| 26 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.92991055 |
| 27 | Stomach cancer (HP:0012126) | 2.91480853 |
| 28 | Stenosis of the external auditory canal (HP:0000402) | 2.85677664 |
| 29 | Stomatitis (HP:0010280) | 2.81113912 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.80709745 |
| 31 | Chromsome breakage (HP:0040012) | 2.73644801 |
| 32 | Slow saccadic eye movements (HP:0000514) | 2.66661811 |
| 33 | Reticulocytopenia (HP:0001896) | 2.59505708 |
| 34 | Hypokinesia (HP:0002375) | 2.57296506 |
| 35 | Glossoptosis (HP:0000162) | 2.56126133 |
| 36 | Missing ribs (HP:0000921) | 2.55882602 |
| 37 | Abnormality of the renal medulla (HP:0100957) | 2.54970705 |
| 38 | Congenital, generalized hypertrichosis (HP:0004540) | 2.49614960 |
| 39 | Blepharitis (HP:0000498) | 2.44341707 |
| 40 | Bifid tongue (HP:0010297) | 2.43628863 |
| 41 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.42256298 |
| 42 | Vascular calcification (HP:0004934) | 2.39233418 |
| 43 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 2.38132665 |
| 44 | Vertebral hypoplasia (HP:0008417) | 2.38132665 |
| 45 | Scanning speech (HP:0002168) | 2.37147406 |
| 46 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.36413555 |
| 47 | Increased cerebral lipofuscin (HP:0011813) | 2.31329399 |
| 48 | Parakeratosis (HP:0001036) | 2.30351945 |
| 49 | Testicular atrophy (HP:0000029) | 2.29695242 |
| 50 | Clubbing of toes (HP:0100760) | 2.29071978 |
| 51 | Microretrognathia (HP:0000308) | 2.26498120 |
| 52 | Abnormality of DNA repair (HP:0003254) | 2.24918637 |
| 53 | Male pseudohermaphroditism (HP:0000037) | 2.24356586 |
| 54 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.24105342 |
| 55 | Optic nerve coloboma (HP:0000588) | 2.24102287 |
| 56 | Erythema (HP:0010783) | 2.21743035 |
| 57 | Abolished electroretinogram (ERG) (HP:0000550) | 2.20022475 |
| 58 | Abnormality of saccadic eye movements (HP:0000570) | 2.19554136 |
| 59 | Hypoproteinemia (HP:0003075) | 2.18563839 |
| 60 | Furrowed tongue (HP:0000221) | 2.15479821 |
| 61 | Ectropion (HP:0000656) | 2.13298733 |
| 62 | Ectopic kidney (HP:0000086) | 2.12095811 |
| 63 | Viral hepatitis (HP:0006562) | 2.10552281 |
| 64 | Panhypogammaglobulinemia (HP:0003139) | 2.07186442 |
| 65 | Neonatal short-limb short stature (HP:0008921) | 2.06901464 |
| 66 | Subacute progressive viral hepatitis (HP:0006572) | 2.06634900 |
| 67 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.06178337 |
| 68 | Febrile seizures (HP:0002373) | 2.03252811 |
| 69 | Cardiovascular calcification (HP:0011915) | 2.01808637 |
| 70 | Exercise-induced muscle cramps (HP:0003710) | 1.97736211 |
| 71 | Dysmetric saccades (HP:0000641) | 1.96210636 |
| 72 | Hypoglycemic coma (HP:0001325) | 1.95181952 |
| 73 | Fibular hypoplasia (HP:0003038) | 1.92082149 |
| 74 | Hemiparesis (HP:0001269) | 1.91379144 |
| 75 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.89622158 |
| 76 | Alveolar cell carcinoma (HP:0006519) | 1.88580236 |
| 77 | Abnormality of male internal genitalia (HP:0000022) | 1.87266215 |
| 78 | Mesangial abnormality (HP:0001966) | 1.84957790 |
| 79 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.84821214 |
| 80 | Keratitis (HP:0000491) | 1.83306250 |
| 81 | Cystic liver disease (HP:0006706) | 1.83107784 |
| 82 | Progressive macrocephaly (HP:0004481) | 1.82812954 |
| 83 | Poor speech (HP:0002465) | 1.82444404 |
| 84 | Attenuation of retinal blood vessels (HP:0007843) | 1.81745127 |
| 85 | Anhidrosis (HP:0000970) | 1.81048005 |
| 86 | Breast carcinoma (HP:0003002) | 1.80973772 |
| 87 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.80245147 |
| 88 | Respiratory distress (HP:0002098) | 1.79012794 |
| 89 | Limb dystonia (HP:0002451) | 1.77994278 |
| 90 | Gaze-evoked nystagmus (HP:0000640) | 1.77908106 |
| 91 | Abnormality of the preputium (HP:0100587) | 1.76413252 |
| 92 | Decreased central vision (HP:0007663) | 1.76279094 |
| 93 | Hypoplasia of the pons (HP:0012110) | 1.75990082 |
| 94 | Optic disc pallor (HP:0000543) | 1.75367868 |
| 95 | IgG deficiency (HP:0004315) | 1.74613011 |
| 96 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.72298853 |
| 97 | Asplenia (HP:0001746) | 1.70888649 |
| 98 | Global brain atrophy (HP:0002283) | 1.69440139 |
| 99 | Micronodular cirrhosis (HP:0001413) | 1.68744234 |
| 100 | Absent thumb (HP:0009777) | 1.68445112 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MST4 | 8.54499810 |
| 2 | GRK1 | 6.35247382 |
| 3 | EPHA2 | 3.14552506 |
| 4 | ADRBK2 | 2.71374319 |
| 5 | TIE1 | 2.41076720 |
| 6 | MAP3K3 | 2.39408038 |
| 7 | BRSK2 | 2.27329030 |
| 8 | WEE1 | 1.79021261 |
| 9 | TRIM28 | 1.73526046 |
| 10 | BUB1 | 1.71968917 |
| 11 | STK10 | 1.69906793 |
| 12 | NUAK1 | 1.65331378 |
| 13 | DYRK3 | 1.63797901 |
| 14 | TLK1 | 1.62535365 |
| 15 | TEC | 1.61325167 |
| 16 | CSNK1A1L | 1.59002289 |
| 17 | STK3 | 1.55788431 |
| 18 | CSNK1G3 | 1.53009297 |
| 19 | CASK | 1.49880741 |
| 20 | IKBKB | 1.45219769 |
| 21 | BMPR2 | 1.41062032 |
| 22 | STK38 | 1.36272287 |
| 23 | DYRK1A | 1.31988168 |
| 24 | ZAK | 1.31729499 |
| 25 | TSSK6 | 1.27827741 |
| 26 | EIF2AK3 | 1.27627342 |
| 27 | CSNK1G1 | 1.19582453 |
| 28 | OXSR1 | 1.17453124 |
| 29 | TAOK1 | 1.08817837 |
| 30 | FRK | 1.07242864 |
| 31 | ITK | 1.05739182 |
| 32 | CSNK1G2 | 1.02274199 |
| 33 | PRKCI | 1.02023470 |
| 34 | TNIK | 1.01891481 |
| 35 | MAP3K14 | 0.93356605 |
| 36 | BMPR1B | 0.89774295 |
| 37 | MAP4K2 | 0.87635380 |
| 38 | SRPK1 | 0.86401253 |
| 39 | STK39 | 0.81675230 |
| 40 | MKNK2 | 0.80875873 |
| 41 | EIF2AK1 | 0.80036437 |
| 42 | TBK1 | 0.70574803 |
| 43 | PTK2B | 0.70524493 |
| 44 | LATS1 | 0.70340546 |
| 45 | ADRBK1 | 0.69444005 |
| 46 | TAOK3 | 0.68347246 |
| 47 | NME2 | 0.67433036 |
| 48 | TAOK2 | 0.67241856 |
| 49 | BCR | 0.65550118 |
| 50 | PASK | 0.61471401 |
| 51 | BRSK1 | 0.61108166 |
| 52 | CSNK1A1 | 0.59549372 |
| 53 | CLK1 | 0.57466978 |
| 54 | VRK2 | 0.56453930 |
| 55 | TESK2 | 0.56036844 |
| 56 | MAP3K1 | 0.54040078 |
| 57 | MKNK1 | 0.53755848 |
| 58 | FGFR3 | 0.52700601 |
| 59 | DAPK2 | 0.52479489 |
| 60 | PHKG2 | 0.50319523 |
| 61 | PHKG1 | 0.50319523 |
| 62 | CCNB1 | 0.49785643 |
| 63 | SIK3 | 0.49210029 |
| 64 | VRK1 | 0.48038552 |
| 65 | CHUK | 0.46892323 |
| 66 | NEK1 | 0.45227590 |
| 67 | BTK | 0.41453389 |
| 68 | PRKCG | 0.41374742 |
| 69 | PIK3CA | 0.41243929 |
| 70 | PLK3 | 0.41022049 |
| 71 | INSRR | 0.39865625 |
| 72 | PLK1 | 0.39202911 |
| 73 | PRKCE | 0.38700455 |
| 74 | ROCK1 | 0.35938633 |
| 75 | FER | 0.35469060 |
| 76 | GRK5 | 0.35104907 |
| 77 | MATK | 0.34440677 |
| 78 | PBK | 0.33894534 |
| 79 | PAK1 | 0.33693521 |
| 80 | EGFR | 0.32192589 |
| 81 | EIF2AK2 | 0.30841897 |
| 82 | PRKCQ | 0.30745843 |
| 83 | DAPK1 | 0.29926686 |
| 84 | MAP3K4 | 0.29808732 |
| 85 | STK38L | 0.29295973 |
| 86 | AKT2 | 0.29118231 |
| 87 | CDK3 | 0.28767114 |
| 88 | PRKD2 | 0.28391849 |
| 89 | WNK4 | 0.27933478 |
| 90 | FES | 0.26778990 |
| 91 | PRKACG | 0.26617126 |
| 92 | MAP3K8 | 0.25734409 |
| 93 | NLK | 0.25310287 |
| 94 | PDK2 | 0.24717845 |
| 95 | FGFR1 | 0.24436777 |
| 96 | PRKCA | 0.22080567 |
| 97 | TTK | 0.21837089 |
| 98 | MAPK4 | 0.19497717 |
| 99 | ATM | 0.19147070 |
| 100 | NTRK3 | 0.19071864 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 3.58871176 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.55230269 |
| 3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.50130983 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.48756858 |
| 5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.42046772 |
| 6 | Phototransduction_Homo sapiens_hsa04744 | 2.39878078 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.35044592 |
| 8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.29529679 |
| 9 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.15059758 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.08812671 |
| 11 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.99138525 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.96213374 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.94355914 |
| 14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.89482496 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.89171766 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.85270558 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.73462798 |
| 18 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.73105611 |
| 19 | Base excision repair_Homo sapiens_hsa03410 | 1.72900264 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.71395256 |
| 21 | Circadian rhythm_Homo sapiens_hsa04710 | 1.59127010 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.58039250 |
| 23 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.56946330 |
| 24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.54604666 |
| 25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.47960552 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.42832404 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.42691623 |
| 28 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.38114442 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.37292012 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.34086788 |
| 31 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.32081403 |
| 32 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.31546662 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.31316617 |
| 34 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.28629329 |
| 35 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.22303231 |
| 36 | Homologous recombination_Homo sapiens_hsa03440 | 1.22056872 |
| 37 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.14938854 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14360951 |
| 39 | Taste transduction_Homo sapiens_hsa04742 | 1.13139932 |
| 40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.10033000 |
| 41 | Retinol metabolism_Homo sapiens_hsa00830 | 1.09242867 |
| 42 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.08608627 |
| 43 | RNA polymerase_Homo sapiens_hsa03020 | 1.07453318 |
| 44 | Other glycan degradation_Homo sapiens_hsa00511 | 1.06903924 |
| 45 | Protein export_Homo sapiens_hsa03060 | 1.02798985 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02195500 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.99401578 |
| 48 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.95426541 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.92200076 |
| 50 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.91869236 |
| 51 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.85503031 |
| 52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.83278038 |
| 53 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.80927481 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.79298712 |
| 55 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.79053825 |
| 56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75738164 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.74969499 |
| 58 | RNA transport_Homo sapiens_hsa03013 | 0.73227591 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72450425 |
| 60 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.69319764 |
| 61 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69055005 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.68258359 |
| 63 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.67082372 |
| 64 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.66887565 |
| 65 | Morphine addiction_Homo sapiens_hsa05032 | 0.63700893 |
| 66 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60350943 |
| 67 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.60128425 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.60082628 |
| 69 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.59380442 |
| 70 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.56867314 |
| 71 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.55823639 |
| 72 | Parkinsons disease_Homo sapiens_hsa05012 | 0.53904808 |
| 73 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.53318569 |
| 74 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.50590587 |
| 75 | Spliceosome_Homo sapiens_hsa03040 | 0.49546135 |
| 76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.48564386 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.48392950 |
| 78 | Tight junction_Homo sapiens_hsa04530 | 0.48013776 |
| 79 | Hepatitis C_Homo sapiens_hsa05160 | 0.47326531 |
| 80 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.47202571 |
| 81 | Measles_Homo sapiens_hsa05162 | 0.46641000 |
| 82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46176702 |
| 83 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.46135422 |
| 84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44212614 |
| 85 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.44164559 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43172688 |
| 87 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.41696191 |
| 88 | Viral myocarditis_Homo sapiens_hsa05416 | 0.38990183 |
| 89 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.38415837 |
| 90 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.34860017 |
| 91 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.34794692 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.34728732 |
| 93 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.33555665 |
| 94 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33051671 |
| 95 | Mismatch repair_Homo sapiens_hsa03430 | 0.32039042 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30441347 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30050498 |
| 98 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.28190479 |
| 99 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.26883913 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.26635781 |

