CCZ1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)6.08866979
2nuclear pore organization (GO:0006999)5.85647786
3regulation of DNA methylation (GO:0044030)5.29538377
4ribosome assembly (GO:0042255)5.29404604
5DNA deamination (GO:0045006)5.16530324
6mitotic chromosome condensation (GO:0007076)5.05157649
7protein localization to chromosome, centromeric region (GO:0071459)4.89956267
8regulation of meiosis I (GO:0060631)4.88907417
9regulation of histone H3-K9 methylation (GO:0051570)4.72693762
10pore complex assembly (GO:0046931)4.70231620
11protein localization to kinetochore (GO:0034501)4.66820294
12positive regulation of chromosome segregation (GO:0051984)4.46931947
13positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.38657919
14positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.38657919
15positive regulation of mitotic sister chromatid separation (GO:1901970)4.38657919
16proteasome assembly (GO:0043248)4.36128752
17telomere maintenance via semi-conservative replication (GO:0032201)4.30508155
18DNA strand elongation involved in DNA replication (GO:0006271)4.29521192
19ribosomal small subunit biogenesis (GO:0042274)4.28130082
20regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.27515683
21DNA replication checkpoint (GO:0000076)4.25443019
22regulation of nuclear cell cycle DNA replication (GO:0033262)4.21126213
23mitotic metaphase plate congression (GO:0007080)4.17165992
24ribosomal large subunit biogenesis (GO:0042273)4.16384761
25DNA replication initiation (GO:0006270)4.08196062
26DNA strand elongation (GO:0022616)4.07487326
27rRNA modification (GO:0000154)4.06528806
28maturation of SSU-rRNA (GO:0030490)4.05382900
29mitotic sister chromatid cohesion (GO:0007064)4.01823160
30transcription elongation from RNA polymerase III promoter (GO:0006385)3.94362611
31termination of RNA polymerase III transcription (GO:0006386)3.94362611
32ribonucleoprotein complex biogenesis (GO:0022613)3.93327859
33piRNA metabolic process (GO:0034587)3.89789825
34positive regulation of histone H3-K4 methylation (GO:0051571)3.86225454
35telomere maintenance via recombination (GO:0000722)3.84971651
36CENP-A containing nucleosome assembly (GO:0034080)3.82770357
37deoxyribonucleotide biosynthetic process (GO:0009263)3.80939432
38ribosome biogenesis (GO:0042254)3.80667368
39chromatin remodeling at centromere (GO:0031055)3.76414784
40DNA damage response, detection of DNA damage (GO:0042769)3.72275846
41paraxial mesoderm development (GO:0048339)3.69839248
42negative regulation of histone methylation (GO:0031061)3.68940579
43spliceosomal snRNP assembly (GO:0000387)3.67796950
447-methylguanosine mRNA capping (GO:0006370)3.67285372
45DNA methylation involved in gamete generation (GO:0043046)3.65608837
46establishment of integrated proviral latency (GO:0075713)3.63990660
47telomere maintenance via telomere lengthening (GO:0010833)3.62295059
48rRNA processing (GO:0006364)3.61893938
49mitotic recombination (GO:0006312)3.59007313
50folic acid-containing compound biosynthetic process (GO:0009396)3.58996299
51regulation of RNA export from nucleus (GO:0046831)3.58674905
52DNA-dependent DNA replication (GO:0006261)3.57993040
53transcription-coupled nucleotide-excision repair (GO:0006283)3.57746408
547-methylguanosine RNA capping (GO:0009452)3.57339246
55RNA capping (GO:0036260)3.57339246
56rRNA metabolic process (GO:0016072)3.51772356
57metaphase plate congression (GO:0051310)3.49414220
58meiotic cell cycle (GO:0051321)3.48718160
59maturation of 5.8S rRNA (GO:0000460)3.47774334
60peptidyl-lysine dimethylation (GO:0018027)3.47647347
61protein localization to chromosome (GO:0034502)3.46471212
62histone H2B ubiquitination (GO:0033523)3.45170046
63regulation of double-strand break repair via homologous recombination (GO:0010569)3.42644892
64nucleobase biosynthetic process (GO:0046112)3.42339878
65pseudouridine synthesis (GO:0001522)3.42258067
66chromatin assembly (GO:0031497)3.41688298
67mitochondrial DNA replication (GO:0006264)3.41533167
68nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.40080793
69viral transcription (GO:0019083)3.39848735
70negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.38286204
71deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.38047309
72transcription from RNA polymerase I promoter (GO:0006360)3.38005069
73ribosomal small subunit assembly (GO:0000028)3.37517116
74termination of RNA polymerase I transcription (GO:0006363)3.37191066
75purine nucleobase biosynthetic process (GO:0009113)3.36880252
76anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.36315712
77translational termination (GO:0006415)3.36021118
78positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.34269507
79DNA replication-dependent nucleosome assembly (GO:0006335)3.32002425
80DNA replication-dependent nucleosome organization (GO:0034723)3.32002425
81DNA replication-independent nucleosome organization (GO:0034724)3.31033845
82DNA replication-independent nucleosome assembly (GO:0006336)3.31033845
83regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.30900569
84deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.30289827
85gene silencing by RNA (GO:0031047)3.29327407
86kinetochore assembly (GO:0051382)3.27984728
87formation of translation preinitiation complex (GO:0001731)3.27850325
88transcription elongation from RNA polymerase I promoter (GO:0006362)3.27844200
89spliceosomal complex assembly (GO:0000245)3.26873048
90negative regulation of DNA-dependent DNA replication (GO:2000104)3.26871774
91nucleotide-excision repair, DNA gap filling (GO:0006297)3.26841161
92regulation of helicase activity (GO:0051095)3.25022839
93regulation of translational termination (GO:0006449)3.24580438
94regulation of mitotic metaphase/anaphase transition (GO:0030071)3.24199425
95regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.24199425
96histone exchange (GO:0043486)3.23482671
97regulation of chromosome segregation (GO:0051983)3.21024015
98RNA destabilization (GO:0050779)3.20852578
99exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.20675746
100regulation of translational fidelity (GO:0006450)3.20577020
101translational initiation (GO:0006413)3.19037512
102chromatin assembly or disassembly (GO:0006333)3.18835128
103kinetochore organization (GO:0051383)3.18176054
104regulation of centriole replication (GO:0046599)3.17150355
105regulation of mitotic sister chromatid separation (GO:0010965)3.13358410
106regulation of mitotic sister chromatid segregation (GO:0033047)3.13358410
107regulation of sister chromatid segregation (GO:0033045)3.13358410
108mitotic nuclear envelope disassembly (GO:0007077)3.11795618
109negative regulation of ligase activity (GO:0051352)3.09061812
110negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.09061812
111L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.07413398
112translesion synthesis (GO:0019985)3.06477327
113rRNA methylation (GO:0031167)3.06099312
114translation (GO:0006412)3.05709216
115nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.04937809
116RNA stabilization (GO:0043489)3.04754377
117mRNA stabilization (GO:0048255)3.04754377
118sister chromatid cohesion (GO:0007062)3.04596760
119establishment of chromosome localization (GO:0051303)3.04372666
120translational elongation (GO:0006414)3.03417651
121regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.02769143
122DNA damage induced protein phosphorylation (GO:0006975)3.02515803
123signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.01376015
124signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.01376015
125signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.01376015
126RNA methylation (GO:0001510)2.99843368
127DNA unwinding involved in DNA replication (GO:0006268)2.99516360
128signal transduction involved in DNA damage checkpoint (GO:0072422)2.98329551
129signal transduction involved in DNA integrity checkpoint (GO:0072401)2.98329551
130positive regulation of histone methylation (GO:0031062)2.98074792
131cellular component biogenesis (GO:0044085)2.98048742
132nucleobase-containing small molecule interconversion (GO:0015949)2.96964734
133regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.96759028
134transcription initiation from RNA polymerase I promoter (GO:0006361)2.96585866
135centriole replication (GO:0007099)2.96577743
136deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.96178360
137SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.96086462
138signal transduction involved in cell cycle checkpoint (GO:0072395)2.95580437
139spindle checkpoint (GO:0031577)2.94573336
140negative regulation of chromosome segregation (GO:0051985)2.93984670
141regulation of centrosome cycle (GO:0046605)2.93749806
142positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.93170360
143membrane disassembly (GO:0030397)2.92307805
144nuclear envelope disassembly (GO:0051081)2.92307805
145regulation of nucleobase-containing compound transport (GO:0032239)2.91302886
146cotranslational protein targeting to membrane (GO:0006613)2.91245999
147regulation of mitochondrial translation (GO:0070129)2.91087548
148DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.90256197
149regulation of sister chromatid cohesion (GO:0007063)2.90181733
150DNA replication (GO:0006260)2.89315311
151negative regulation of mitotic sister chromatid separation (GO:2000816)2.89233414
152negative regulation of sister chromatid segregation (GO:0033046)2.89233414
153negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.89233414
154negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.89233414
155negative regulation of mitotic sister chromatid segregation (GO:0033048)2.89233414
156establishment of viral latency (GO:0019043)2.89086015
157regulation of spindle organization (GO:0090224)2.86827780
158mitotic spindle checkpoint (GO:0071174)2.83955984
159RNA-dependent DNA replication (GO:0006278)2.82583297
160ATP-dependent chromatin remodeling (GO:0043044)2.82164125
161heterochromatin organization (GO:0070828)2.81621277
162female gamete generation (GO:0007292)2.81573666
163sister chromatid segregation (GO:0000819)2.80713713
164mitotic sister chromatid segregation (GO:0000070)2.80158421
165double-strand break repair via nonhomologous end joining (GO:0006303)2.77312467
166non-recombinational repair (GO:0000726)2.77312467
167single strand break repair (GO:0000012)2.75376507
168histone monoubiquitination (GO:0010390)2.74267670
169DNA duplex unwinding (GO:0032508)2.72743529
170pre-miRNA processing (GO:0031054)2.71456373
171regulation of spindle checkpoint (GO:0090231)2.71172654
172mitotic spindle assembly checkpoint (GO:0007094)2.71139116
173SMAD protein complex assembly (GO:0007183)2.71095228
174DNA alkylation (GO:0006305)2.71059192

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.11657459
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.35657332
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.25685239
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.80110237
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.62965710
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.53428449
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.39618967
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.38589608
9FOXM1_23109430_ChIP-Seq_U2OS_Human3.24845157
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.10153584
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.06783080
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.02107286
13MYC_19030024_ChIP-ChIP_MESCs_Mouse3.01179476
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.00687140
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.94510525
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.92920969
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.69050616
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.68882810
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.61372382
20VDR_23849224_ChIP-Seq_CD4+_Human2.53342355
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.52048333
22SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.51573000
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.42507865
24SALL1_21062744_ChIP-ChIP_HESCs_Human2.41553757
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.40237578
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38489070
27HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.38145981
28HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36812156
29XRN2_22483619_ChIP-Seq_HELA_Human2.32926487
30* PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.24490573
31MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.14412771
32E2F1_18555785_ChIP-Seq_MESCs_Mouse2.12855177
33ELK1_19687146_ChIP-ChIP_HELA_Human2.01436971
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.99504056
35FOXP3_21729870_ChIP-Seq_TREG_Human1.99094139
36DCP1A_22483619_ChIP-Seq_HELA_Human1.98899601
37MYCN_18555785_ChIP-Seq_MESCs_Mouse1.93148992
38TTF2_22483619_ChIP-Seq_HELA_Human1.91568239
39HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.90661060
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.89209796
41GABP_19822575_ChIP-Seq_HepG2_Human1.77834539
42AR_21909140_ChIP-Seq_LNCAP_Human1.76376121
43THAP11_20581084_ChIP-Seq_MESCs_Mouse1.72961448
44NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.68857767
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67865164
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.67484081
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.66595566
48MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.64850923
49SRF_21415370_ChIP-Seq_HL-1_Mouse1.64215407
50KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.63355011
51KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.63355011
52KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.63355011
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.62360196
54FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.62266408
55YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56976536
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.54102245
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.53418491
58TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.49065546
59* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.47942247
60KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.46413889
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.43620241
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.41077387
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.39345392
64PADI4_21655091_ChIP-ChIP_MCF-7_Human1.37997159
65BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.36897816
66FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.36866131
67WT1_19549856_ChIP-ChIP_CCG9911_Human1.36433290
68KDM5A_27292631_Chip-Seq_BREAST_Human1.33976810
69CIITA_25753668_ChIP-Seq_RAJI_Human1.33561937
70SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.32778622
71ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31342029
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.31039542
73KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.27993425
74ESR1_15608294_ChIP-ChIP_MCF-7_Human1.26024101
75ELK1_22589737_ChIP-Seq_MCF10A_Human1.24283820
76SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.23785353
77POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23421848
78FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18484854
79TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18050352
80CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17986653
81RBPJ_22232070_ChIP-Seq_NCS_Mouse1.17231517
82MYC_18940864_ChIP-ChIP_HL60_Human1.16695534
83TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16178230
84PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.15510260
85NOTCH1_21737748_ChIP-Seq_TLL_Human1.14531731
86SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.11651819
87STAT3_1855785_ChIP-Seq_MESCs_Mouse1.10740248
88TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.04154921
89ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03914590
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03836078
91CHD1_26751641_Chip-Seq_LNCaP_Human1.03477501
92NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02224594
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01634474
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01335401
95HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.00537895
96SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00408382
97CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00349159
98ERG_20887958_ChIP-Seq_HPC-7_Mouse0.99716034
99TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.99565808
100TCF3_18692474_ChIP-Seq_MEFs_Mouse0.97952096
101GATA1_26923725_Chip-Seq_HPCs_Mouse0.97004535
102PKCTHETA_26484144_Chip-Seq_BREAST_Human0.93753450
103DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.93681199
104KLF4_18555785_ChIP-Seq_MESCs_Mouse0.93548602
105EWS_26573619_Chip-Seq_HEK293_Human0.92624074
106NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.91723735
107CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.90625868
108SOX17_20123909_ChIP-Seq_XEN_Mouse0.90227220
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88795045
110EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.86368787
111TP63_17297297_ChIP-ChIP_HaCaT_Human0.85883715
112SOX2_18692474_ChIP-Seq_MEFs_Mouse0.85476093
113SPI1_23547873_ChIP-Seq_NB4_Human0.80844575
114TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.80641873
115KAP1_22055183_ChIP-Seq_ESCs_Mouse0.79131771
116ELF5_23300383_ChIP-Seq_T47D_Human0.78024396
117CLOCK_20551151_ChIP-Seq_293T_Human0.77764299
118SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.77534628
119CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.76471816
120NANOG_16153702_ChIP-ChIP_HESCs_Human0.75903465
121HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75115136
122SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.74613942
123OCT4_18692474_ChIP-Seq_MEFs_Mouse0.74360649
124IRF1_19129219_ChIP-ChIP_H3396_Human0.74053439
125TFEB_21752829_ChIP-Seq_HELA_Human0.73872746
126CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.72038783
127SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.69721584
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.69487979

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.62545795
2MP0003111_abnormal_nucleus_morphology4.60733270
3MP0008057_abnormal_DNA_replication4.12740775
4MP0010094_abnormal_chromosome_stability4.09166779
5MP0008058_abnormal_DNA_repair3.80462521
6MP0004957_abnormal_blastocyst_morpholog3.77923147
7MP0003077_abnormal_cell_cycle3.76736641
8MP0010234_abnormal_vibrissa_follicle3.58856537
9MP0003718_maternal_effect3.00050507
10MP0008932_abnormal_embryonic_tissue2.95185968
11MP0008007_abnormal_cellular_replicative2.86594377
12MP0008877_abnormal_DNA_methylation2.79346576
13MP0005499_abnormal_olfactory_system2.57209471
14MP0005394_taste/olfaction_phenotype2.57209471
15MP0003786_premature_aging2.27496490
16MP0003941_abnormal_skin_development2.05120169
17MP0003705_abnormal_hypodermis_morpholog2.03780601
18MP0002160_abnormal_reproductive_system2.02115589
19MP0002877_abnormal_melanocyte_morpholog1.98450368
20MP0000566_synostosis1.97631105
21MP0004133_heterotaxia1.93399373
22MP0003806_abnormal_nucleotide_metabolis1.82656710
23MP0001730_embryonic_growth_arrest1.79169364
24MP0006292_abnormal_olfactory_placode1.77230870
25MP0010030_abnormal_orbit_morphology1.75436245
26MP0005076_abnormal_cell_differentiation1.71811899
27MP0000350_abnormal_cell_proliferation1.71117391
28MP0005389_reproductive_system_phenotype1.68700186
29MP0002277_abnormal_respiratory_mucosa1.64687474
30MP0002210_abnormal_sex_determination1.64219744
31MP0009379_abnormal_foot_pigmentation1.63563248
32MP0004185_abnormal_adipocyte_glucose1.63206659
33MP0009053_abnormal_anal_canal1.63087198
34MP0002796_impaired_skin_barrier1.55631594
35MP0003315_abnormal_perineum_morphology1.50431912
36MP0004233_abnormal_muscle_weight1.49641015
37MP0003123_paternal_imprinting1.46680199
38MP0001145_abnormal_male_reproductive1.44012353
39MP0002233_abnormal_nose_morphology1.42423099
40MP0003136_yellow_coat_color1.41930509
41MP0005501_abnormal_skin_physiology1.40811109
42MP0008260_abnormal_autophagy1.40209923
43MP0000313_abnormal_cell_death1.38189931
44MP0001853_heart_inflammation1.29939516
45MP0003890_abnormal_embryonic-extraembry1.29331106
46MP0001929_abnormal_gametogenesis1.28156219
47MP0000428_abnormal_craniofacial_morphol1.27876161
48MP0004381_abnormal_hair_follicle1.27817748
49MP0003186_abnormal_redox_activity1.27099725
50MP0000653_abnormal_sex_gland1.26989392
51MP0001188_hyperpigmentation1.26792291
52MP0000490_abnormal_crypts_of1.26653797
53MP0001672_abnormal_embryogenesis/_devel1.25532669
54MP0005380_embryogenesis_phenotype1.25532669
55MP0010307_abnormal_tumor_latency1.24070525
56MP0002085_abnormal_embryonic_tissue1.24064932
57MP0001919_abnormal_reproductive_system1.19478089
58MP0001697_abnormal_embryo_size1.16635799
59MP0010678_abnormal_skin_adnexa1.15838213
60MP0002080_prenatal_lethality1.15196043
61MP0002102_abnormal_ear_morphology1.15154983
62MP0002019_abnormal_tumor_incidence1.14637501
63MP0000762_abnormal_tongue_morphology1.14298886
64MP0005451_abnormal_body_composition1.13102620
65MP0003937_abnormal_limbs/digits/tail_de1.12047290
66MP0003699_abnormal_female_reproductive1.11736046
67MP0000537_abnormal_urethra_morphology1.08673566
68MP0010352_gastrointestinal_tract_polyps1.08536343
69MP0009333_abnormal_splenocyte_physiolog1.04206239
70MP0005395_other_phenotype1.03649517
71MP0002009_preneoplasia1.03413103
72MP0000377_abnormal_hair_follicle1.02655909
73MP0001293_anophthalmia1.00875542
74MP0003755_abnormal_palate_morphology1.00621364
75MP0005409_darkened_coat_color0.97455828
76MP0002697_abnormal_eye_size0.96976302
77MP0003984_embryonic_growth_retardation0.96907458
78MP0000613_abnormal_salivary_gland0.95179933
79MP0002088_abnormal_embryonic_growth/wei0.94226469
80MP0005075_abnormal_melanosome_morpholog0.94124496
81MP0009672_abnormal_birth_weight0.92982002
82MP0003385_abnormal_body_wall0.92011425
83MP0002111_abnormal_tail_morphology0.92003177
84MP0001286_abnormal_eye_development0.91295679
85MP0001119_abnormal_female_reproductive0.90588412
86MP0003567_abnormal_fetal_cardiomyocyte0.90153836
87MP0003121_genomic_imprinting0.90128657
88MP0002234_abnormal_pharynx_morphology0.88993331
89MP0006035_abnormal_mitochondrial_morpho0.88795397
90MP0002084_abnormal_developmental_patter0.88338461
91MP0003935_abnormal_craniofacial_develop0.87941044
92MP0000427_abnormal_hair_cycle0.87128115
93MP0003861_abnormal_nervous_system0.85900350
94MP0005408_hypopigmentation0.85316778
95MP0000858_altered_metastatic_potential0.85132600
96MP0000358_abnormal_cell_content/0.84489236
97MP0000432_abnormal_head_morphology0.84405064
98MP0001986_abnormal_taste_sensitivity0.84258798
99MP0005377_hearing/vestibular/ear_phenot0.84141947
100MP0003878_abnormal_ear_physiology0.84141947
101MP0009250_abnormal_appendicular_skeleto0.84014751
102MP0002092_abnormal_eye_morphology0.83920188
103MP0003119_abnormal_digestive_system0.83651797
104MP0002132_abnormal_respiratory_system0.83267897
105MP0005174_abnormal_tail_pigmentation0.82241301
106MP0003698_abnormal_male_reproductive0.81201162
107MP0004197_abnormal_fetal_growth/weight/0.80256881
108MP0009697_abnormal_copulation0.80192216
109MP0002138_abnormal_hepatobiliary_system0.80186559
110MP0000627_abnormal_mammary_gland0.78641362
111MP0002060_abnormal_skin_morphology0.76553564
112MP0001915_intracranial_hemorrhage0.76508001
113MP0004808_abnormal_hematopoietic_stem0.76030032
114MP0003936_abnormal_reproductive_system0.75989897
115MP0002396_abnormal_hematopoietic_system0.75451891
116MP0008789_abnormal_olfactory_epithelium0.73852381
117MP0005384_cellular_phenotype0.73517041
118MP0003183_abnormal_peptide_metabolism0.72505612
119MP0003938_abnormal_ear_development0.71946968
120MP0001727_abnormal_embryo_implantation0.71379903
121MP0005197_abnormal_uvea_morphology0.71129817
122MP0000703_abnormal_thymus_morphology0.70287313
123MP0001881_abnormal_mammary_gland0.69577796
124MP0000015_abnormal_ear_pigmentation0.68588429
125MP0002086_abnormal_extraembryonic_tissu0.68448337
126MP0000689_abnormal_spleen_morphology0.67670937
127MP0005621_abnormal_cell_physiology0.67471066
128MP0003448_altered_tumor_morphology0.67401024
129MP0003221_abnormal_cardiomyocyte_apopto0.67331969
130MP0001216_abnormal_epidermal_layer0.66393764
131MP0002722_abnormal_immune_system0.65552670
132MP0001186_pigmentation_phenotype0.65080153
133MP0003566_abnormal_cell_adhesion0.64405999
134MP0001661_extended_life_span0.64324871
135MP0002098_abnormal_vibrissa_morphology0.64001207
136MP0002254_reproductive_system_inflammat0.63647322
137MP0005257_abnormal_intraocular_pressure0.61135067
138MP0005410_abnormal_fertilization0.61114940
139MP0005171_absent_coat_pigmentation0.60509270
140MP0008995_early_reproductive_senescence0.59416996
141MP0002938_white_spotting0.58325690
142MP0000647_abnormal_sebaceous_gland0.58167682
143MP0001485_abnormal_pinna_reflex0.57720404
144MP0002161_abnormal_fertility/fecundity0.56883322
145MP0002751_abnormal_autonomic_nervous0.56499510

Predicted human phenotypes

RankGene SetZ-score
1Progressive external ophthalmoplegia (HP:0000590)5.21513398
2Birth length less than 3rd percentile (HP:0003561)5.03168421
3Breast hypoplasia (HP:0003187)4.94330576
4Chromosomal breakage induced by crosslinking agents (HP:0003221)4.55885234
5Chromsome breakage (HP:0040012)4.36013057
6Reticulocytopenia (HP:0001896)4.18517893
7Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.02320101
8Cerebral hypomyelination (HP:0006808)3.94234726
9Carpal bone hypoplasia (HP:0001498)3.48390299
10Papillary thyroid carcinoma (HP:0002895)3.47697655
11Meckel diverticulum (HP:0002245)3.28805817
12Absent radius (HP:0003974)3.28662020
13Duplicated collecting system (HP:0000081)3.26749013
14Nephroblastoma (Wilms tumor) (HP:0002667)3.22332842
15Rough bone trabeculation (HP:0100670)3.21045517
16Macrocytic anemia (HP:0001972)3.19146679
17Abnormality of the preputium (HP:0100587)3.08443068
18Aplasia involving forearm bones (HP:0009822)3.04630912
19Absent forearm bone (HP:0003953)3.04630912
20Embryonal renal neoplasm (HP:0011794)3.04033265
21Abnormality of the ileum (HP:0001549)3.03920620
22Abnormality of chromosome stability (HP:0003220)3.02486063
23External ophthalmoplegia (HP:0000544)3.00038381
24Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.97829128
25Oral leukoplakia (HP:0002745)2.96009589
26Malignant gastrointestinal tract tumors (HP:0006749)2.95496433
27Gastrointestinal carcinoma (HP:0002672)2.95496433
28Uterine leiomyosarcoma (HP:0002891)2.95178323
29Leiomyosarcoma (HP:0100243)2.95178323
30Abnormality of the renal collecting system (HP:0004742)2.92863025
31Granulocytopenia (HP:0001913)2.91213221
32Aplasia/Hypoplasia of the earlobes (HP:0009906)2.89438450
33Patellar aplasia (HP:0006443)2.88184347
34Proximal tubulopathy (HP:0000114)2.87324497
35Abnormality of cells of the erythroid lineage (HP:0012130)2.82996477
36Subacute progressive viral hepatitis (HP:0006572)2.79126112
37Abnormality of the phalanges of the hallux (HP:0010057)2.78970872
38Aplasia/Hypoplasia of the patella (HP:0006498)2.77353925
39Facial hemangioma (HP:0000329)2.72594878
40Progressive muscle weakness (HP:0003323)2.71870006
41Impulsivity (HP:0100710)2.71484955
42Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.69801827
43Abnormal number of erythroid precursors (HP:0012131)2.68339374
44Transitional cell carcinoma of the bladder (HP:0006740)2.65437272
45Capillary hemangiomas (HP:0005306)2.64339787
46Supernumerary spleens (HP:0009799)2.63962073
47Thyroid carcinoma (HP:0002890)2.62868616
48Overlapping toe (HP:0001845)2.62685723
49Multiple enchondromatosis (HP:0005701)2.62604995
50Aplasia/Hypoplasia of the uvula (HP:0010293)2.60844010
51Absent thumb (HP:0009777)2.60514713
52Aplastic anemia (HP:0001915)2.59802105
53Abnormal trabecular bone morphology (HP:0100671)2.57438466
54Bone marrow hypocellularity (HP:0005528)2.54415172
55Secondary amenorrhea (HP:0000869)2.51184552
56Premature graying of hair (HP:0002216)2.50853228
57Horseshoe kidney (HP:0000085)2.49639136
58Pallor (HP:0000980)2.48979068
59Aplasia/Hypoplasia involving the musculature (HP:0001460)2.47942378
60Triphalangeal thumb (HP:0001199)2.45949260
61Bladder neoplasm (HP:0009725)2.45183145
62Bladder carcinoma (HP:0002862)2.45183145
63Stomach cancer (HP:0012126)2.42162998
64Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.40898888
65Deep philtrum (HP:0002002)2.39081526
66Rhabdomyosarcoma (HP:0002859)2.37988804
67Oligodactyly (hands) (HP:0001180)2.36149832
68Neoplasm of the pancreas (HP:0002894)2.35302585
69Microvesicular hepatic steatosis (HP:0001414)2.32764907
70Renal cell carcinoma (HP:0005584)2.32465267
71Cleft eyelid (HP:0000625)2.30669349
72Breast carcinoma (HP:0003002)2.30299866
73Colon cancer (HP:0003003)2.29380097
74Premature ovarian failure (HP:0008209)2.28901033
75Deep palmar crease (HP:0006191)2.27459954
76Sandal gap (HP:0001852)2.23969203
77Uterine neoplasm (HP:0010784)2.23753324
78Hypokinesia (HP:0002375)2.22605958
79Increased nuchal translucency (HP:0010880)2.21947368
80CNS hypomyelination (HP:0003429)2.21070287
81Cafe-au-lait spot (HP:0000957)2.20550344
82Oligodactyly (HP:0012165)2.18282893
83Microglossia (HP:0000171)2.17241239
84Increased serum lactate (HP:0002151)2.17238580
85Heterotopia (HP:0002282)2.16705936
86Microretrognathia (HP:0000308)2.15290582
87Neoplasm of the colon (HP:0100273)2.14983507
88Duodenal stenosis (HP:0100867)2.14322921
89Small intestinal stenosis (HP:0012848)2.14322921
90Stillbirth (HP:0003826)2.14306878
91Trismus (HP:0000211)2.13058729
923-Methylglutaconic aciduria (HP:0003535)2.11692009
93Selective tooth agenesis (HP:0001592)2.10489004
94Pancytopenia (HP:0001876)2.09847572
95Osteomalacia (HP:0002749)2.09485171
96Aplasia/Hypoplasia of the sacrum (HP:0008517)2.08956817
97Medulloblastoma (HP:0002885)2.08481799
98Biliary tract neoplasm (HP:0100574)2.08411807
99Abnormality of chromosome segregation (HP:0002916)2.08009276
100Cellular immunodeficiency (HP:0005374)2.07948279
101Gonadotropin excess (HP:0000837)2.05622704
102Abnormal spermatogenesis (HP:0008669)2.04110347
103Poikiloderma (HP:0001029)2.03684154
104Type I transferrin isoform profile (HP:0003642)2.03106013
105Termporal pattern (HP:0011008)2.01687954
106Insidious onset (HP:0003587)2.01687954
107Breast aplasia (HP:0100783)2.01023457
108Abnormality of the septum pellucidum (HP:0007375)2.00023380
109Aplasia/hypoplasia of the uterus (HP:0008684)1.99970104
110Median cleft lip (HP:0000161)1.99542252
111Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.99281802
112Decreased activity of mitochondrial respiratory chain (HP:0008972)1.99281802
113Prolonged neonatal jaundice (HP:0006579)1.98488152
114Ectopic kidney (HP:0000086)1.96748271
115Megaloblastic anemia (HP:0001889)1.96175308
116Neoplasm of the small intestine (HP:0100833)1.94962260
117Vertebral arch anomaly (HP:0008438)1.93963083
118Tracheoesophageal fistula (HP:0002575)1.93160725
119Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.92460838
120Agnosia (HP:0010524)1.92034265
121Parakeratosis (HP:0001036)1.91368184
122Exercise intolerance (HP:0003546)1.91137102
123Abnormal lung lobation (HP:0002101)1.90948673
124Ureteral duplication (HP:0000073)1.90494626
125Aplasia/Hypoplasia of the breasts (HP:0010311)1.90240710
126Arteriovenous malformation (HP:0100026)1.89177613
127Clubbing of toes (HP:0100760)1.88120632
128Hepatosplenomegaly (HP:0001433)1.87591946
129Sloping forehead (HP:0000340)1.87005087
130Ankle contracture (HP:0006466)1.86952478
131Enlarged penis (HP:0000040)1.85812554
132Pancreatic cysts (HP:0001737)1.84610976
133Neoplasm of the adrenal cortex (HP:0100641)1.84450081
134Abnormality of abdominal situs (HP:0011620)1.84050802
135Abdominal situs inversus (HP:0003363)1.84050802
136Cortical dysplasia (HP:0002539)1.83230101
137Hypoplasia of the radius (HP:0002984)1.82201644
138Short thumb (HP:0009778)1.82154458
139Abnormality of the anterior horn cell (HP:0006802)1.82018278
140Degeneration of anterior horn cells (HP:0002398)1.82018278
141Breech presentation (HP:0001623)1.81729137
142Sparse eyelashes (HP:0000653)1.80535413
143Stenosis of the external auditory canal (HP:0000402)1.79682469
144Ependymoma (HP:0002888)1.79646484
145Increased hepatocellular lipid droplets (HP:0006565)1.79541771
146Myelodysplasia (HP:0002863)1.79495914
147Lip pit (HP:0100267)1.79332309
148Abnormal foot bone ossification (HP:0010675)1.79293995
149Pseudobulbar signs (HP:0002200)1.78258219
150Acute lymphatic leukemia (HP:0006721)1.78196771
151Spinal cord lesions (HP:0100561)1.78101992
152Syringomyelia (HP:0003396)1.78101992
153Facial cleft (HP:0002006)1.77446205
154Metaphyseal dysplasia (HP:0100255)1.77292854
155Abnormality of the duodenum (HP:0002246)1.76420078
156Asplenia (HP:0001746)1.75675369
157Astrocytoma (HP:0009592)1.75193880
158Abnormality of the astrocytes (HP:0100707)1.75193880
159High anterior hairline (HP:0009890)1.74521179
160Shoulder girdle muscle weakness (HP:0003547)1.73665636
161Squamous cell carcinoma (HP:0002860)1.72879835
162Lower limb hyperreflexia (HP:0002395)1.72844407
163Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.72690135
164Cubitus valgus (HP:0002967)1.72424149
165Cystic hygroma (HP:0000476)1.69709987
166Micronodular cirrhosis (HP:0001413)1.68883006
167Hypoplasia of the pons (HP:0012110)1.68394261
168Deviation of the thumb (HP:0009603)1.68281372
169Glioma (HP:0009733)1.68018001
170Spinal cord compression (HP:0002176)1.68005291
171Truncal obesity (HP:0001956)1.66464169
172Short tibia (HP:0005736)1.66300484
173Embryonal neoplasm (HP:0002898)1.66148970

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK35.52940078
2BUB14.87205586
3PLK44.75247019
4RIPK13.85653081
5ZAK3.38181003
6STK163.33348450
7WEE13.15124375
8IRAK43.01470049
9MAP3K92.85449429
10SRPK12.70765953
11IRAK22.56467500
12EIF2AK12.56296076
13TTK2.54299664
14MAP3K132.50401800
15MARK12.32435003
16ARAF2.26904724
17IRAK12.20976395
18TESK22.17591931
19CDC72.12858820
20EIF2AK32.06895511
21DYRK31.90477116
22STK241.89826116
23EPHA21.89140815
24TLK11.83077434
25PNCK1.78113969
26EEF2K1.76164282
27CDK121.75300459
28TSSK61.75179283
29VRK11.74842522
30MAP3K121.73949815
31ACVR1B1.58647582
32CDK91.57845391
33PLK11.52408704
34PLK31.44565640
35PBK1.41460632
36ATR1.30718153
37MKNK21.27196610
38NEK21.26385020
39STK38L1.22241446
40MKNK11.21048331
41STK391.20592047
42NTRK21.17458360
43KSR11.16875892
44PKN21.16204637
45CHEK21.14903709
46RPS6KB21.14406631
47MAP3K101.13556465
48NME21.12796934
49SMG11.09051972
50MOS1.08796881
51AURKB1.08638209
52BRSK21.06048366
53NEK91.03932076
54DYRK21.03068444
55AURKA0.99829011
56TRIB30.99044223
57PAK40.98908755
58TAF10.98747793
59EIF2AK20.97318048
60KDR0.96812255
61ERBB40.95178378
62CDK70.92634935
63PRKCI0.90372372
64KSR20.88593970
65STK40.88124421
66DMPK0.86589622
67MAP3K140.86086819
68MAP3K80.82342776
69TNIK0.80051462
70MST1R0.78521545
71MAPKAPK30.76528192
72CHEK10.75926250
73TESK10.72969317
74ERBB30.72478323
75PTK20.70385036
76CDK60.66852553
77ABL20.66715567
78RAF10.65876338
79ATM0.65006118
80PDGFRA0.63787644
81RPS6KA50.62935375
82NME10.62375858
83BRD40.61295196
84BCKDK0.60830569
85ICK0.60689330
86BLK0.60250048
87FLT30.60099340
88BRAF0.56041411
89CSNK2A10.55056109
90RPS6KA40.54911269
91LIMK10.54785927
92NEK60.54351606
93MTOR0.54178938
94CSNK2A20.53279343
95LATS20.52563775
96PASK0.52081266
97PAK10.50491510
98CDK80.47540251
99LMTK20.46411822
100NTRK10.46032049
101MST40.45755389
102CDK20.44500763
103ALK0.39957880
104BCR0.39118401
105AKT30.38523439
106PIM20.38166103
107AKT20.37856709
108CDK40.36889366
109NLK0.36455387
110STK100.36400564
111CDK10.36398775
112NUAK10.36142305
113ILK0.34553984
114RPS6KB10.34127804
115CSNK1E0.33723794
116MAP2K20.31445124
117BRSK10.28923474
118SCYL20.28570940
119CAMK2B0.27628267
120NEK10.25463430
121PIM10.24660029
122CSNK1G30.23831569
123STK30.23603200
124MELK0.22438190
125CAMK2D0.22410161
126BMPR1B0.21939981
127TGFBR10.21384451
128CAMK2G0.20471127
129PRKDC0.19853844
130IKBKB0.19681572
131GRK10.18802731
132CDC42BPA0.16381461
133LATS10.16223221
134CDK190.13871756
135CSNK1A1L0.13187759
136YES10.11784310
137MET0.10407127
138CSNK1G10.09670848
139MAP3K110.09480895
140TEC0.08978398
141CLK10.08921139

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.34654516
2RNA polymerase_Homo sapiens_hsa030204.16894362
3Proteasome_Homo sapiens_hsa030503.94822499
4Mismatch repair_Homo sapiens_hsa034303.84785843
5Ribosome_Homo sapiens_hsa030103.81709767
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.54744030
7Spliceosome_Homo sapiens_hsa030403.17005299
8Homologous recombination_Homo sapiens_hsa034403.01586737
9Fanconi anemia pathway_Homo sapiens_hsa034602.96230785
10Pyrimidine metabolism_Homo sapiens_hsa002402.86827860
11Nucleotide excision repair_Homo sapiens_hsa034202.68185693
12RNA transport_Homo sapiens_hsa030132.57300392
13Thyroid cancer_Homo sapiens_hsa052162.51037114
14One carbon pool by folate_Homo sapiens_hsa006702.38087328
15Base excision repair_Homo sapiens_hsa034102.23521508
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.16828184
17Basal transcription factors_Homo sapiens_hsa030222.16675916
18Cell cycle_Homo sapiens_hsa041102.15160888
19Non-homologous end-joining_Homo sapiens_hsa034501.97089163
20RNA degradation_Homo sapiens_hsa030181.76838157
21p53 signaling pathway_Homo sapiens_hsa041151.62101565
22Purine metabolism_Homo sapiens_hsa002301.60718797
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.59806707
24Colorectal cancer_Homo sapiens_hsa052101.56797380
25Adherens junction_Homo sapiens_hsa045201.56353315
26Pancreatic cancer_Homo sapiens_hsa052121.53750951
27Caffeine metabolism_Homo sapiens_hsa002321.51713246
28Protein export_Homo sapiens_hsa030601.35540344
29Oxidative phosphorylation_Homo sapiens_hsa001901.32357704
30Chronic myeloid leukemia_Homo sapiens_hsa052201.29882984
31Epstein-Barr virus infection_Homo sapiens_hsa051691.28455494
32Vitamin B6 metabolism_Homo sapiens_hsa007501.26260804
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.26198284
34Huntingtons disease_Homo sapiens_hsa050161.24202982
35Endometrial cancer_Homo sapiens_hsa052131.22700981
36Glutathione metabolism_Homo sapiens_hsa004801.17251099
37mRNA surveillance pathway_Homo sapiens_hsa030151.14195129
38Hippo signaling pathway_Homo sapiens_hsa043901.11172224
39Folate biosynthesis_Homo sapiens_hsa007901.10400479
40Parkinsons disease_Homo sapiens_hsa050121.08821511
41Systemic lupus erythematosus_Homo sapiens_hsa053221.06040996
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03663890
43Lysine degradation_Homo sapiens_hsa003101.00934598
44Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00055221
45Renal cell carcinoma_Homo sapiens_hsa052110.97524673
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.95896636
47Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.95141199
48Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88770823
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.88086429
50Sphingolipid signaling pathway_Homo sapiens_hsa040710.87834900
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.86536706
52Non-small cell lung cancer_Homo sapiens_hsa052230.84280585
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.81303660
54Bladder cancer_Homo sapiens_hsa052190.80164855
55Prostate cancer_Homo sapiens_hsa052150.76733515
56Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.76289019
57Pentose phosphate pathway_Homo sapiens_hsa000300.76111972
58Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.73882325
59mTOR signaling pathway_Homo sapiens_hsa041500.73846021
60ErbB signaling pathway_Homo sapiens_hsa040120.72262651
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.71255198
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.71134722
63Dorso-ventral axis formation_Homo sapiens_hsa043200.68514552
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67224022
65Viral carcinogenesis_Homo sapiens_hsa052030.67090880
66Arachidonic acid metabolism_Homo sapiens_hsa005900.65796689
67Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.65501712
68Hepatitis B_Homo sapiens_hsa051610.65050167
69VEGF signaling pathway_Homo sapiens_hsa043700.64852435
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.63498700
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62983452
72Herpes simplex infection_Homo sapiens_hsa051680.62815133
73Pyruvate metabolism_Homo sapiens_hsa006200.62399668
74NF-kappa B signaling pathway_Homo sapiens_hsa040640.60797933
75Sphingolipid metabolism_Homo sapiens_hsa006000.59264411
76Other glycan degradation_Homo sapiens_hsa005110.59049491
77Wnt signaling pathway_Homo sapiens_hsa043100.58578039
78Linoleic acid metabolism_Homo sapiens_hsa005910.58504360
79Proteoglycans in cancer_Homo sapiens_hsa052050.57357255
80Melanoma_Homo sapiens_hsa052180.56172950
81Inositol phosphate metabolism_Homo sapiens_hsa005620.56152877
82Alzheimers disease_Homo sapiens_hsa050100.55270275
83Oocyte meiosis_Homo sapiens_hsa041140.55131727
84Selenocompound metabolism_Homo sapiens_hsa004500.54684184
85Metabolic pathways_Homo sapiens_hsa011000.52766663
86Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.52363124
87N-Glycan biosynthesis_Homo sapiens_hsa005100.52205500
88Pathways in cancer_Homo sapiens_hsa052000.50905990
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49265933
90Acute myeloid leukemia_Homo sapiens_hsa052210.48133168
91Arginine and proline metabolism_Homo sapiens_hsa003300.48080807
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.47913651
93Antigen processing and presentation_Homo sapiens_hsa046120.47715063
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.46805926
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46660119
96Longevity regulating pathway - mammal_Homo sapiens_hsa042110.46575511
97Insulin signaling pathway_Homo sapiens_hsa049100.46165069
98Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45959538
99FoxO signaling pathway_Homo sapiens_hsa040680.44612227
100Circadian rhythm_Homo sapiens_hsa047100.43702804
101Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41552870
102Ether lipid metabolism_Homo sapiens_hsa005650.40616183
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38003125
104Glioma_Homo sapiens_hsa052140.36533442
105Biosynthesis of amino acids_Homo sapiens_hsa012300.36458209
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35758735
107HTLV-I infection_Homo sapiens_hsa051660.35448890
108Focal adhesion_Homo sapiens_hsa045100.34982151
109Sulfur relay system_Homo sapiens_hsa041220.34228282
110Steroid biosynthesis_Homo sapiens_hsa001000.30515845
111Regulation of actin cytoskeleton_Homo sapiens_hsa048100.29292818
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.27112995
113Primary immunodeficiency_Homo sapiens_hsa053400.26567525
114RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.26443346
115Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26346563
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.26007936
117Prolactin signaling pathway_Homo sapiens_hsa049170.25913355
118Renin-angiotensin system_Homo sapiens_hsa046140.25693789
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.24513690
120Regulation of autophagy_Homo sapiens_hsa041400.24473652
121Notch signaling pathway_Homo sapiens_hsa043300.24438862
122Basal cell carcinoma_Homo sapiens_hsa052170.23992498
123Vitamin digestion and absorption_Homo sapiens_hsa049770.23160065
124Phosphatidylinositol signaling system_Homo sapiens_hsa040700.21788702
125Phototransduction_Homo sapiens_hsa047440.21516726
126Apoptosis_Homo sapiens_hsa042100.21501490
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21026512
128Retinol metabolism_Homo sapiens_hsa008300.20510423
129Tyrosine metabolism_Homo sapiens_hsa003500.20420659
130Alcoholism_Homo sapiens_hsa050340.18656327
131MicroRNAs in cancer_Homo sapiens_hsa052060.18368007
132Shigellosis_Homo sapiens_hsa051310.18155747
133Measles_Homo sapiens_hsa051620.17973321
134Phenylalanine metabolism_Homo sapiens_hsa003600.17724574
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.17245078
136TGF-beta signaling pathway_Homo sapiens_hsa043500.16954537
137Small cell lung cancer_Homo sapiens_hsa052220.15961315
138Legionellosis_Homo sapiens_hsa051340.15383887
139Autoimmune thyroid disease_Homo sapiens_hsa053200.14485550
140Asthma_Homo sapiens_hsa053100.14301092
141Transcriptional misregulation in cancer_Homo sapiens_hsa052020.12228212
142Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.09121725
143beta-Alanine metabolism_Homo sapiens_hsa004100.08885157
144Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.08806203
145Intestinal immune network for IgA production_Homo sapiens_hsa046720.07766087
146Carbon metabolism_Homo sapiens_hsa012000.07658761
147Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.06754591
148Allograft rejection_Homo sapiens_hsa053300.06412338
149Hematopoietic cell lineage_Homo sapiens_hsa046400.06030357
150Tight junction_Homo sapiens_hsa045300.04320738

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »