CD226

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)9.72484729
2negative regulation of cell killing (GO:0031342)9.72484729
3negative T cell selection (GO:0043383)8.05243854
4negative thymic T cell selection (GO:0045060)7.72220848
5positive regulation of gamma-delta T cell activation (GO:0046645)7.40112503
6regulation of isotype switching to IgG isotypes (GO:0048302)6.93192102
7interferon-gamma production (GO:0032609)6.69107962
8positive thymic T cell selection (GO:0045059)6.59970227
9cellular response to interleukin-15 (GO:0071350)6.56657647
10response to interleukin-15 (GO:0070672)6.33981132
11thymic T cell selection (GO:0045061)6.33672515
12positive T cell selection (GO:0043368)6.23619299
13regulation of gamma-delta T cell differentiation (GO:0045586)5.90713192
14T cell selection (GO:0045058)5.82156968
15positive regulation of interleukin-2 biosynthetic process (GO:0045086)5.79943691
16positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.79069681
17antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.72914416
18antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.72914416
19T cell migration (GO:0072678)5.52446514
20regulation of gamma-delta T cell activation (GO:0046643)5.42552114
21positive regulation of alpha-beta T cell proliferation (GO:0046641)5.35092846
22regulation of alpha-beta T cell proliferation (GO:0046640)5.17020325
23antigen processing and presentation of endogenous antigen (GO:0019883)5.10762597
24T cell costimulation (GO:0031295)4.97904000
25negative regulation of T cell mediated immunity (GO:0002710)4.95514819
26lymphocyte costimulation (GO:0031294)4.92176211
27regulation of T cell tolerance induction (GO:0002664)4.91893172
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.89849898
29regulation of B cell receptor signaling pathway (GO:0050855)4.83844055
30T cell receptor signaling pathway (GO:0050852)4.81167856
31leukocyte aggregation (GO:0070486)4.75758546
32positive regulation of isotype switching (GO:0045830)4.73366804
33tolerance induction (GO:0002507)4.55188124
34regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.47739234
35positive regulation by symbiont of host defense response (GO:0052509)4.30464938
36modulation by symbiont of host defense response (GO:0052031)4.30464938
37modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.30464938
38modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.30464938
39positive regulation by organism of defense response of other organism involved in symbiotic interact4.30464938
40modulation by symbiont of host immune response (GO:0052553)4.30464938
41activated T cell proliferation (GO:0050798)4.29870903
42regulation of interleukin-2 biosynthetic process (GO:0045076)4.28437723
43B cell receptor signaling pathway (GO:0050853)4.26327547
44positive regulation of humoral immune response (GO:0002922)4.17847146
45* regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.15482092
46* regulation of natural killer cell mediated immunity (GO:0002715)4.15482092
47* positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.12223375
48* positive regulation of natural killer cell mediated immunity (GO:0002717)4.12223375
49positive regulation of interleukin-2 production (GO:0032743)4.11766290
50positive regulation of DNA recombination (GO:0045911)4.11365265
51antigen receptor-mediated signaling pathway (GO:0050851)4.08919443
52* regulation of leukocyte mediated cytotoxicity (GO:0001910)4.07757451
53regulation of T cell receptor signaling pathway (GO:0050856)4.07263778
54regulation of antigen receptor-mediated signaling pathway (GO:0050854)4.06919942
55neutrophil activation involved in immune response (GO:0002283)4.03331826
56regulation of T cell mediated cytotoxicity (GO:0001914)3.97865426
57regulation of isotype switching (GO:0045191)3.97255953
58natural killer cell activation (GO:0030101)3.90622854
59positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.89969416
60regulation of response to interferon-gamma (GO:0060330)3.86025760
61thrombin receptor signaling pathway (GO:0070493)3.83826042
62negative regulation of lymphocyte mediated immunity (GO:0002707)3.79293605
63positive regulation of granulocyte differentiation (GO:0030854)3.78229738
64regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.77203450
65* positive regulation of immunoglobulin mediated immune response (GO:0002891)3.72505165
66* positive regulation of B cell mediated immunity (GO:0002714)3.72505165
67CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.71899653
68T-helper cell differentiation (GO:0042093)3.71899653
69* regulation of cell killing (GO:0031341)3.70374968
70cellular extravasation (GO:0045123)3.69524651
71positive regulation of T-helper 1 type immune response (GO:0002827)3.64763386
72* positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.63539912
73mast cell activation (GO:0045576)3.60546672
74lymphocyte migration (GO:0072676)3.57658585
75alpha-beta T cell activation (GO:0046631)3.56682610
76microglial cell activation (GO:0001774)3.56315440
77positive regulation of B cell differentiation (GO:0045579)3.54870987
78regulation of tolerance induction (GO:0002643)3.53754100
79alpha-beta T cell differentiation involved in immune response (GO:0002293)3.51811486
80alpha-beta T cell activation involved in immune response (GO:0002287)3.51811486
81T cell differentiation involved in immune response (GO:0002292)3.51811486
82regulation of T-helper 1 type immune response (GO:0002825)3.50838596
83sequestering of actin monomers (GO:0042989)3.50026406
84positive regulation of tolerance induction (GO:0002645)3.46590701
85alpha-beta T cell differentiation (GO:0046632)3.46382323
86CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.44042737
87positive regulation of defense response to virus by host (GO:0002230)3.42253640
88regulation of B cell differentiation (GO:0045577)3.41955290
89T cell differentiation (GO:0030217)3.41211453
90* regulation of immunoglobulin mediated immune response (GO:0002889)3.38575305
91regulation of interleukin-12 biosynthetic process (GO:0045075)3.37827142
92leukocyte cell-cell adhesion (GO:0007159)3.35420993
93regulation of T-helper 1 cell differentiation (GO:0045625)3.32064336
94cytidine metabolic process (GO:0046087)3.30692525
95cytidine catabolic process (GO:0006216)3.30692525
96cytidine deamination (GO:0009972)3.30692525
97positive regulation of immunoglobulin production (GO:0002639)3.30009819
98heterotypic cell-cell adhesion (GO:0034113)3.29497324
99* positive regulation of cell killing (GO:0031343)3.28887095
100* regulation of B cell mediated immunity (GO:0002712)3.27929706
101positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.27721975
102interferon-gamma-mediated signaling pathway (GO:0060333)3.27573413
103T cell activation (GO:0042110)3.26486925
104response to type I interferon (GO:0034340)3.26309401
105macrophage activation involved in immune response (GO:0002281)3.25286942
106negative regulation of interleukin-12 production (GO:0032695)3.24829114
107cellular response to type I interferon (GO:0071357)3.23969501
108type I interferon signaling pathway (GO:0060337)3.23969501
109regulation of regulatory T cell differentiation (GO:0045589)3.23660399
110neutrophil activation (GO:0042119)3.23460915
111T cell activation involved in immune response (GO:0002286)3.22593801
112myeloid cell activation involved in immune response (GO:0002275)3.22118624
113negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)3.22001488
114positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.21663088
115B cell homeostasis (GO:0001782)3.21255004
116positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.21165737
117positive regulation of interferon-gamma production (GO:0032729)3.20905033
118* regulation of lymphocyte mediated immunity (GO:0002706)3.19500905
119response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.18219616
120response to host immune response (GO:0052572)3.18219616
121T cell proliferation (GO:0042098)3.17790291
122immunoglobulin mediated immune response (GO:0016064)3.17217290
123G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.17054156
124* positive regulation of lymphocyte mediated immunity (GO:0002708)3.16937478
125negative regulation of T cell receptor signaling pathway (GO:0050860)3.16690158
126positive regulation of T cell mediated cytotoxicity (GO:0001916)3.15400256
127regulation of type I interferon-mediated signaling pathway (GO:0060338)3.15088604
128negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.14472375
129Arp2/3 complex-mediated actin nucleation (GO:0034314)3.13842315
130pyrimidine ribonucleoside catabolic process (GO:0046133)3.04315092
131B cell mediated immunity (GO:0019724)3.02522350
132regulation of platelet aggregation (GO:0090330)3.02209703
133leukocyte degranulation (GO:0043299)2.99592807
134granulocyte activation (GO:0036230)2.96848989
135leukocyte migration involved in inflammatory response (GO:0002523)2.95279245
136angiogenesis involved in wound healing (GO:0060055)2.91078241
137regulation of interferon-beta biosynthetic process (GO:0045357)2.87174194
138lymphocyte homeostasis (GO:0002260)2.85723755
139antigen processing and presentation via MHC class Ib (GO:0002475)2.85413292
140megakaryocyte development (GO:0035855)2.85218942
141negative regulation of B cell proliferation (GO:0030889)2.84358149
142defense response to protozoan (GO:0042832)2.82474732
143response to host (GO:0075136)2.79126039
144response to host defenses (GO:0052200)2.79126039
145response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.79126039
146negative regulation of leukocyte mediated immunity (GO:0002704)2.78425459

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse8.40967891
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human6.87362518
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.11403278
4IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.73655825
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.62188377
6STAT3_20064451_ChIP-Seq_CD4+T_Mouse4.39854177
7* STAT4_19710469_ChIP-ChIP_TH1__Mouse4.07649980
8RUNX_20019798_ChIP-Seq_JUKART_Human3.81825322
9IRF8_21731497_ChIP-ChIP_J774_Mouse3.76619274
10FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse3.67442511
11* MYB_26560356_Chip-Seq_TH2_Human3.44876563
12MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.19321707
13* MAF_26560356_Chip-Seq_TH1_Human2.93016304
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.90956984
15* MYB_26560356_Chip-Seq_TH1_Human2.79696677
16MYC_22102868_ChIP-Seq_BL_Human2.56894770
17NOTCH1_21737748_ChIP-Seq_TLL_Human2.55023903
18IRF8_27001747_Chip-Seq_BMDM_Mouse2.51552146
19UTX_26944678_Chip-Seq_JUKART_Human2.50390274
20SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.33417889
21BP1_19119308_ChIP-ChIP_Hs578T_Human2.28566568
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.24277123
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.22703968
24* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.15186636
25* GATA3_27048872_Chip-Seq_THYMUS_Human2.13281587
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.10215895
27MYB_21317192_ChIP-Seq_ERMYB_Mouse2.04798850
28* MAF_26560356_Chip-Seq_TH2_Human2.02078358
29SPI1_23547873_ChIP-Seq_NB4_Human2.01242714
30RUNX1_22412390_ChIP-Seq_EML_Mouse1.95053674
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.93256237
32RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.90505264
33E2F7_22180533_ChIP-Seq_HELA_Human1.89534899
34EGR1_19374776_ChIP-ChIP_THP-1_Human1.87783558
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.72350047
36VDR_21846776_ChIP-Seq_THP-1_Human1.68564363
37GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.66785391
38KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.65918139
39SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.64544144
40E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.63306160
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.61204093
42ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57103891
43BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.55873121
44MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.55834992
45BRD4_27068464_Chip-Seq_AML-cells_Mouse1.53238165
46TCF7_22412390_ChIP-Seq_EML_Mouse1.51048037
47GATA1_19941826_ChIP-Seq_K562_Human1.50855991
48IKZF1_21737484_ChIP-ChIP_HCT116_Human1.49846064
49VDR_24763502_ChIP-Seq_THP-1_Human1.48994399
50VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.45542519
51* GATA3_26560356_Chip-Seq_TH2_Human1.43726923
52EZH2_22144423_ChIP-Seq_EOC_Human1.38835685
53PU_27001747_Chip-Seq_BMDM_Mouse1.38772129
54RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.37945752
55SPI1_23127762_ChIP-Seq_K562_Human1.36808309
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.34458062
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.33885458
58SCL_19346495_ChIP-Seq_HPC-7_Human1.33466465
59KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.28373817
60PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27192693
61GATA2_22383799_ChIP-Seq_G1ME_Mouse1.26759444
62GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26076125
63CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22837350
64CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22213829
65KDM2B_26808549_Chip-Seq_DND41_Human1.19489241
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17548747
67CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10127295
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09969498
69PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02880964
70VDR_23849224_ChIP-Seq_CD4+_Human1.00946719
71* GATA3_26560356_Chip-Seq_TH1_Human1.00371583
72VDR_24787735_ChIP-Seq_THP-1_Human0.99401644
73LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.96484904
74PCGF2_27294783_Chip-Seq_NPCs_Mouse0.96095618
75STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.96058220
76ERG_20887958_ChIP-Seq_HPC-7_Mouse0.95274529
77PU.1_20513432_ChIP-Seq_Bcells_Mouse0.94618429
78GATA2_21666600_ChIP-Seq_HMVEC_Human0.94412250
79VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.94287907
80CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93416149
81GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91702797
82PRDM14_20953172_ChIP-Seq_ESCs_Human0.91307009
83KDM2B_26808549_Chip-Seq_SUP-B15_Human0.89621413
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.89567973
85LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.89351283
86STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89171236
87* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.88043399
88PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87186114
89HOXB4_20404135_ChIP-ChIP_EML_Mouse0.87170382
90* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.86670500
91GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85948151
92SUZ12_27294783_Chip-Seq_NPCs_Mouse0.85405383
93NFE2_27457419_Chip-Seq_LIVER_Mouse0.84887129
94Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.84836245
95PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82733588
96NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.82122088
97KDM2B_26808549_Chip-Seq_JURKAT_Human0.81514554
98* IRF1_19129219_ChIP-ChIP_H3396_Human0.80847949
99CIITA_25753668_ChIP-Seq_RAJI_Human0.78839264
100OCT4_21477851_ChIP-Seq_ESCs_Mouse0.78820892
101SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.76986634
102EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.76555644
103EZH2_27294783_Chip-Seq_NPCs_Mouse0.76091839
104PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75650145
105ER_23166858_ChIP-Seq_MCF-7_Human0.74325284
106ELK4_26923725_Chip-Seq_MESODERM_Mouse0.74134652
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.73867390
108ELK3_25401928_ChIP-Seq_HUVEC_Human0.73690498
109TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.73214244
110RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.72907097
111KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.71550656
112SALL4_22934838_ChIP-ChIP_CD34+_Human0.71267324
113FOXP3_21729870_ChIP-Seq_TREG_Human0.69843395
114* GATA1_19941827_ChIP-Seq_MEL_Mouse0.69065887
115RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.68890047
116GATA1_22383799_ChIP-Seq_G1ME_Mouse0.68057890
117GATA1_22025678_ChIP-Seq_K562_Human0.64678938
118ELK1_19687146_ChIP-ChIP_HELA_Human0.64439424
119* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.64213556
120SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.63351253
121TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.63064655
122THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.62779698
123EGR1_19032775_ChIP-ChIP_M12_Human0.60936536
124FLI1_27457419_Chip-Seq_LIVER_Mouse0.60340872
125EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.59146797
126GATA2_19941826_ChIP-Seq_K562_Human0.55977868
127SMRT_27268052_Chip-Seq_Bcells_Human0.54923085
128NCOR1_26117541_ChIP-Seq_K562_Human0.54606373

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.30280986
2MP0003763_abnormal_thymus_physiology5.16046285
3MP0001835_abnormal_antigen_presentation3.92421297
4MP0009785_altered_susceptibility_to3.79640807
5MP0000685_abnormal_immune_system3.62421080
6MP0005000_abnormal_immune_tolerance3.38456796
7MP0001800_abnormal_humoral_immune3.32754567
8MP0006082_CNS_inflammation3.15807590
9MP0009333_abnormal_splenocyte_physiolog3.02213072
10* MP0002420_abnormal_adaptive_immunity3.01153415
11* MP0001819_abnormal_immune_cell3.00713677
12* MP0002723_abnormal_immune_serum3.00651752
13MP0005025_abnormal_response_to2.97843217
14MP0002166_altered_tumor_susceptibility2.97424064
15* MP0005387_immune_system_phenotype2.96624606
16* MP0001790_abnormal_immune_system2.96624606
17MP0002452_abnormal_antigen_presenting2.82013492
18MP0003724_increased_susceptibility_to2.79802221
19* MP0002398_abnormal_bone_marrow2.77307216
20MP0002006_tumorigenesis2.67594560
21MP0002148_abnormal_hypersensitivity_rea2.62960867
22MP0002405_respiratory_system_inflammati2.57668412
23MP0003436_decreased_susceptibility_to2.54593618
24* MP0000716_abnormal_immune_system2.48404932
25MP0000703_abnormal_thymus_morphology2.36205951
26MP0010155_abnormal_intestine_physiology2.32708147
27MP0002722_abnormal_immune_system2.25467616
28MP0002419_abnormal_innate_immunity2.23354058
29MP0000689_abnormal_spleen_morphology2.16778494
30MP0003866_abnormal_defecation2.07724771
31MP0004947_skin_inflammation2.00902748
32* MP0002429_abnormal_blood_cell2.00352864
33MP0001845_abnormal_inflammatory_respons1.93555855
34MP0008004_abnormal_stomach_pH1.75746832
35MP0005464_abnormal_platelet_physiology1.75359740
36MP0003300_gastrointestinal_ulcer1.70378694
37MP0001873_stomach_inflammation1.70001181
38* MP0000858_altered_metastatic_potential1.68007363
39MP0000569_abnormal_digit_pigmentation1.67523800
40MP0002933_joint_inflammation1.66551766
41* MP0003448_altered_tumor_morphology1.58055489
42MP0001853_heart_inflammation1.56609663
43MP0004510_myositis1.54678299
44MP0003303_peritoneal_inflammation1.45815287
45MP0004381_abnormal_hair_follicle1.44588681
46MP0002396_abnormal_hematopoietic_system1.41338601
47MP0005310_abnormal_salivary_gland1.36253328
48MP0008469_abnormal_protein_level1.33434019
49MP0002009_preneoplasia1.26956613
50MP0004130_abnormal_muscle_cell1.17685224
51MP0000015_abnormal_ear_pigmentation1.17558006
52MP0001533_abnormal_skeleton_physiology1.15934978
53MP0004808_abnormal_hematopoietic_stem1.10757753
54MP0005167_abnormal_blood-brain_barrier1.05853914
55MP0000490_abnormal_crypts_of1.05603116
56MP0000465_gastrointestinal_hemorrhage1.05358195
57MP0003045_fibrosis1.05316250
58MP0001851_eye_inflammation1.04413156
59MP0005645_abnormal_hypothalamus_physiol1.03820457
60MP0002132_abnormal_respiratory_system1.03709382
61MP0002998_abnormal_bone_remodeling1.02932260
62MP0008872_abnormal_physiological_respon1.02794736
63MP0009764_decreased_sensitivity_to1.00965898
64* MP0002019_abnormal_tumor_incidence0.98007969
65MP0003183_abnormal_peptide_metabolism0.97927058
66MP0003172_abnormal_lysosome_physiology0.96042885
67MP0001545_abnormal_hematopoietic_system0.91833022
68MP0005397_hematopoietic_system_phenotyp0.91833022
69MP0005075_abnormal_melanosome_morpholog0.91366744
70* MP0009763_increased_sensitivity_to0.86665254
71MP0003828_pulmonary_edema0.86504342
72MP0005174_abnormal_tail_pigmentation0.85767458
73MP0001348_abnormal_lacrimal_gland0.83403329
74MP0004883_abnormal_blood_vessel0.83220375
75MP0004142_abnormal_muscle_tone0.81881527
76MP0001986_abnormal_taste_sensitivity0.79945639
77MP0008877_abnormal_DNA_methylation0.79723555
78MP0009765_abnormal_xenobiotic_induced0.78021148
79MP0003656_abnormal_erythrocyte_physiolo0.77610578
80MP0008057_abnormal_DNA_replication0.75861970
81MP0003453_abnormal_keratinocyte_physiol0.73918549
82MP0000372_irregular_coat_pigmentation0.73916915
83MP0008874_decreased_physiological_sensi0.72789035
84MP0002138_abnormal_hepatobiliary_system0.72254376
85MP0005084_abnormal_gallbladder_morpholo0.70892644
86MP0002163_abnormal_gland_morphology0.68548666
87MP0005166_decreased_susceptibility_to0.67606033
88MP0000230_abnormal_systemic_arterial0.67496525
89MP0000343_altered_response_to0.66895897
90MP0005023_abnormal_wound_healing0.65826517
91MP0003646_muscle_fatigue0.65423250
92MP0002136_abnormal_kidney_physiology0.60692853
93MP0001919_abnormal_reproductive_system0.60117154
94MP0003091_abnormal_cell_migration0.59625739
95MP0008007_abnormal_cellular_replicative0.59181660
96MP0003693_abnormal_embryo_hatching0.59113327
97MP0002693_abnormal_pancreas_physiology0.58850411
98MP0004484_altered_response_of0.57710446
99MP0003638_abnormal_response/metabolism_0.57527461
100MP0004084_abnormal_cardiac_muscle0.54996953
101MP0009642_abnormal_blood_homeostasis0.53301937
102MP0001765_abnormal_ion_homeostasis0.52999448
103MP0001881_abnormal_mammary_gland0.51686659
104MP0005379_endocrine/exocrine_gland_phen0.51642976
105MP0010352_gastrointestinal_tract_polyps0.51429942
106MP0000249_abnormal_blood_vessel0.51077914
107MP0005381_digestive/alimentary_phenotyp0.50729154
108MP0002822_catalepsy0.50206313
109MP0000609_abnormal_liver_physiology0.49410887
110MP0003795_abnormal_bone_structure0.49066936
111MP0003077_abnormal_cell_cycle0.48799327
112MP0000477_abnormal_intestine_morphology0.47922260
113MP0001191_abnormal_skin_condition0.46137291
114MP0001216_abnormal_epidermal_layer0.43146596
115MP0001243_abnormal_dermal_layer0.42897031
116MP0000604_amyloidosis0.42732059
117MP0005076_abnormal_cell_differentiation0.42219935
118MP0000627_abnormal_mammary_gland0.40547022
119MP0003943_abnormal_hepatobiliary_system0.40106257
120MP0005451_abnormal_body_composition0.38881974
121MP0003787_abnormal_imprinting0.37662964
122MP0000367_abnormal_coat/_hair0.37338039
123MP0000613_abnormal_salivary_gland0.35150308
124MP0005390_skeleton_phenotype0.34995064
125MP0002277_abnormal_respiratory_mucosa0.32978312
126MP0001663_abnormal_digestive_system0.32546742
127MP0000313_abnormal_cell_death0.31927538
128MP0005584_abnormal_enzyme/coenzyme_acti0.30631847
129MP0000598_abnormal_liver_morphology0.30427509

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)8.22151591
2Abnormality of T cell number (HP:0011839)8.00769980
3Severe combined immunodeficiency (HP:0004430)6.13605996
4Elevated erythrocyte sedimentation rate (HP:0003565)6.02436389
5Combined immunodeficiency (HP:0005387)5.87457228
6Abnormality of T cells (HP:0002843)5.49351586
7Myositis (HP:0100614)5.27974640
8Increased IgM level (HP:0003496)4.89304367
9Recurrent bronchitis (HP:0002837)4.81883749
10Menorrhagia (HP:0000132)4.75202485
11Increased mean platelet volume (HP:0011877)4.73038139
12IgG deficiency (HP:0004315)4.67083326
13Purpura (HP:0000979)4.64223536
14IgM deficiency (HP:0002850)4.43665248
15Thyroiditis (HP:0100646)4.35136169
16Retrobulbar optic neuritis (HP:0100654)4.23273127
17Optic neuritis (HP:0100653)4.23273127
18Stomatitis (HP:0010280)4.21904694
19Nasal polyposis (HP:0100582)4.20121585
20Recurrent fungal infections (HP:0002841)4.14923699
21Eczematoid dermatitis (HP:0000976)4.12304903
22Gastrointestinal infarctions (HP:0005244)4.11509603
23Abnormality of eosinophils (HP:0001879)4.08653449
24Recurrent viral infections (HP:0004429)3.96397684
25Chronic otitis media (HP:0000389)3.95255913
26Recurrent cutaneous fungal infections (HP:0011370)3.77258134
27Chronic mucocutaneous candidiasis (HP:0002728)3.77258134
28Leukocytosis (HP:0001974)3.70575920
29Autoimmune hemolytic anemia (HP:0001890)3.68221703
30Pustule (HP:0200039)3.67301415
31Orchitis (HP:0100796)3.66203520
32Recurrent abscess formation (HP:0002722)3.62943776
33Vasculitis (HP:0002633)3.59414125
34Hemoptysis (HP:0002105)3.52855546
35Lymphopenia (HP:0001888)3.52780839
36Abnormality of the nasal mucosa (HP:0000433)3.52308651
37Joint swelling (HP:0001386)3.44753750
38Abnormality of cells of the lymphoid lineage (HP:0012140)3.42072459
39Autoimmune thrombocytopenia (HP:0001973)3.28071844
40Keratoconjunctivitis sicca (HP:0001097)3.26123765
41Mediastinal lymphadenopathy (HP:0100721)3.24380005
42Hypergammaglobulinemia (HP:0010702)3.24304659
43Encephalitis (HP:0002383)3.22831042
44Pulmonary infiltrates (HP:0002113)3.21131778
45Abnormality of T cell physiology (HP:0011840)3.18720658
46Abnormality of B cell number (HP:0010975)3.13574056
47B lymphocytopenia (HP:0010976)3.13574056
48IgA deficiency (HP:0002720)3.13294963
49Abnormal delayed hypersensitivity skin test (HP:0002963)3.08985579
50Meningitis (HP:0001287)3.08873322
51Chronic diarrhea (HP:0002028)3.07765116
52Obstructive lung disease (HP:0006536)3.01989338
53Chronic obstructive pulmonary disease (HP:0006510)3.01989338
54Panhypogammaglobulinemia (HP:0003139)2.98567900
55Abnormality of the fingertips (HP:0001211)2.96208790
56Arterial thrombosis (HP:0004420)2.95344363
57Keratoconjunctivitis (HP:0001096)2.94042216
58Eosinophilia (HP:0001880)2.93566240
59Recurrent sinusitis (HP:0011108)2.92360540
60Abnormal platelet function (HP:0011869)2.92134920
61Impaired platelet aggregation (HP:0003540)2.92134920
62Recurrent skin infections (HP:0001581)2.71739309
63Recurrent bacterial skin infections (HP:0005406)2.69667706
64Spontaneous hematomas (HP:0007420)2.68404489
65Bronchitis (HP:0012387)2.68248647
66Gangrene (HP:0100758)2.64079119
67Lymphoma (HP:0002665)2.63944379
68Granulocytopenia (HP:0001913)2.61852763
69Thrombocytosis (HP:0001894)2.57246944
70Pulmonary embolism (HP:0002204)2.55276384
71Hyperlipoproteinemia (HP:0010980)2.43898312
72Chest pain (HP:0100749)2.43013862
73Amaurosis fugax (HP:0100576)2.42340208
74Periodontitis (HP:0000704)2.38859613
75Anorexia (HP:0002039)2.38322668
76Abnormality of the prostate (HP:0008775)2.37820163
77Colitis (HP:0002583)2.34572615
78Basal cell carcinoma (HP:0002671)2.32414694
79Epistaxis (HP:0000421)2.32305827
80Recurrent gram-negative bacterial infections (HP:0005420)2.30219700
81Gastrointestinal inflammation (HP:0004386)2.26226620
82Inflammation of the large intestine (HP:0002037)2.25988370
83Gingival bleeding (HP:0000225)2.24832970
84Cheilitis (HP:0100825)2.22841776
85Gingivitis (HP:0000230)2.20709518
86Recurrent otitis media (HP:0000403)2.19757845
87Abnormal platelet volume (HP:0011876)2.18876476
88Agammaglobulinemia (HP:0004432)2.18664157
89Abnormality of macrophages (HP:0004311)2.17638097
90Increased IgE level (HP:0003212)2.12121767
91Hypoplasia of the thymus (HP:0000778)2.11152169
92Poikilocytosis (HP:0004447)2.10842437
93Chronic sinusitis (HP:0011109)2.07724880
94Petechiae (HP:0000967)2.07078989
95Glomerulopathy (HP:0100820)2.06098937
96Urticaria (HP:0001025)2.04969136
97Papilloma (HP:0012740)2.01359851
98Verrucae (HP:0200043)2.01359851
99Prolonged bleeding time (HP:0003010)1.99360681
100Abnormality of the pleura (HP:0002103)1.98517991
101Ureteral stenosis (HP:0000071)1.96488837
102Arthralgia (HP:0002829)1.94905386
103Skin ulcer (HP:0200042)1.94381840
104Keratitis (HP:0000491)1.94202106
105Abnormality of the endocardium (HP:0004306)1.91982844
106Bronchiectasis (HP:0002110)1.89215221
107Acute hepatic failure (HP:0006554)1.88832295
108Interstitial pulmonary disease (HP:0006530)1.88280857
109Vertigo (HP:0002321)1.87613483
110Gastrointestinal stroma tumor (HP:0100723)1.86717355
111Polyneuropathy (HP:0001271)1.86693708
112Increased density of long bones (HP:0006392)1.84608588
113Hemiplegia (HP:0002301)1.84232881
114Conjunctival telangiectasia (HP:0000524)1.81224138
115Tinnitus (HP:0000360)1.80408796
116Recurrent pneumonia (HP:0006532)1.76696139
117Restrictive lung disease (HP:0002091)1.75849128
1183-Methylglutaconic aciduria (HP:0003535)1.75625741
119Abnormality of the vasculature of the conjunctiva (HP:0008054)1.75452372
120Abnormality of binocular vision (HP:0011514)1.74741516

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK6.73992232
2MAP4K14.80872976
3ITK3.54781248
4JAK33.32736357
5MAP3K143.24206910
6IKBKE3.07115552
7FGFR42.97120457
8ZAP702.90644736
9JAK12.86640102
10TYK22.64353820
11TBK12.43377198
12NLK2.42181095
13MST42.32886357
14BLK2.23784415
15GRK62.09903166
16STK102.08698992
17FGFR32.03090882
18LCK1.92141100
19CSK1.88261095
20TEC1.84189998
21CAMKK21.64456686
22IRAK41.62684802
23PRPF4B1.61800890
24FRK1.59441193
25NME21.45853432
26SYK1.44006440
27IKBKB1.42549098
28BTK1.36065496
29HCK1.35370856
30PIK3CG1.30775897
31IRAK31.27353404
32PTK2B1.20938613
33PRKCQ1.20278572
34MAP3K131.17775273
35MATK1.16124298
36KDR1.16013986
37ACVR1B1.15670553
38TAOK31.13532442
39TSSK61.06394394
40MAP3K121.01719380
41CHUK1.01610044
42CLK11.00076962
43PIM10.98574532
44KIT0.96175272
45PRKCH0.93971495
46CAMKK10.90242869
47JAK20.88964103
48LRRK20.86863703
49NUAK10.82562366
50LYN0.81335016
51GRK50.79410278
52STK240.77244838
53EPHA30.74006819
54MAP3K100.73220873
55MAP2K30.73028630
56SGK20.71584199
57DMPK0.71034843
58NEK90.70997528
59PASK0.69550212
60TESK20.69029463
61STK30.68981576
62PRKD20.68650000
63TNIK0.67962071
64TNK20.67075725
65MARK30.64910797
66FES0.61294011
67DAPK20.60968883
68EPHB10.60567563
69EEF2K0.59247147
70TGFBR20.57929375
71IRAK10.56217803
72BMX0.56198499
73MAPK120.56020319
74TYRO30.53733733
75STK40.53655872
76STK380.53597426
77EIF2AK10.50759653
78BMPR1B0.50488131
79SIK30.49956228
80YES10.49220352
81RPS6KA40.48972861
82TLK10.48953504
83MAP3K110.48096040
84MAP3K50.47620134
85PIM20.46960491
86PDPK10.45145803
87MAP2K60.45100069
88MAP3K70.44140181
89IGF1R0.42148243
90SIK20.41263805
91HIPK20.41127698
92PKN20.40707079
93SGK30.39388298
94PDK10.38163158
95PDGFRB0.37855052
96INSR0.37236821
97FYN0.36673585
98ADRBK10.35035067
99MAPK70.34695278
100GRK10.34465929
101MELK0.34022365
102CDK60.33669137
103MAPK110.33305016
104TAOK20.32375208
105CDC42BPA0.32182338
106MAP3K10.32150034
107ALK0.31343275
108GRK70.30503833
109WNK10.29674997
110ILK0.28759039
111IRAK20.27694303
112RAF10.27294631
113STK110.26616077
114CDK40.26468742
115CDK120.25866581
116FGFR10.25286897
117ABL10.25022269
118BMPR20.25009700
119MAPK130.24854146
120ADRBK20.24645053
121MAPKAPK20.24251575
122RIPK40.24153852
123TTN0.23168996
124CSF1R0.22370674
125PRKCD0.22166660
126CDK90.21286608
127RPS6KA50.20542061
128EIF2AK20.20017730
129FGR0.19740511
130TRPM70.15508038
131MAPK30.15346464
132TAOK10.14890198
133TRIB30.14505905

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053405.33176429
2Graft-versus-host disease_Homo sapiens_hsa053324.77937914
3Allograft rejection_Homo sapiens_hsa053303.77153436
4T cell receptor signaling pathway_Homo sapiens_hsa046603.44551873
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.31115418
6Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046503.30269136
7Intestinal immune network for IgA production_Homo sapiens_hsa046723.12904505
8Measles_Homo sapiens_hsa051622.94822815
9Antigen processing and presentation_Homo sapiens_hsa046122.73836134
10Autoimmune thyroid disease_Homo sapiens_hsa053202.61894349
11NF-kappa B signaling pathway_Homo sapiens_hsa040642.54475960
12Viral myocarditis_Homo sapiens_hsa054162.28609694
13Leishmaniasis_Homo sapiens_hsa051402.14544042
14Hematopoietic cell lineage_Homo sapiens_hsa046402.08710332
15Type I diabetes mellitus_Homo sapiens_hsa049402.05414367
16Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.00215257
17RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.99709964
18Jak-STAT signaling pathway_Homo sapiens_hsa046301.82870174
19Osteoclast differentiation_Homo sapiens_hsa043801.75560868
20Herpes simplex infection_Homo sapiens_hsa051681.58554622
21B cell receptor signaling pathway_Homo sapiens_hsa046621.42995372
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.42394320
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.40170527
24Chemokine signaling pathway_Homo sapiens_hsa040621.39238831
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.37953649
26Toxoplasmosis_Homo sapiens_hsa051451.31426438
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.30633592
28Influenza A_Homo sapiens_hsa051641.30139713
29* Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.23924336
30Staphylococcus aureus infection_Homo sapiens_hsa051501.22856011
31Leukocyte transendothelial migration_Homo sapiens_hsa046701.19831861
32Shigellosis_Homo sapiens_hsa051311.18834421
33Malaria_Homo sapiens_hsa051441.18377624
34Legionellosis_Homo sapiens_hsa051341.18328487
35Hepatitis B_Homo sapiens_hsa051611.15780738
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.14467865
37TNF signaling pathway_Homo sapiens_hsa046681.13738542
38Apoptosis_Homo sapiens_hsa042101.01059544
39Asthma_Homo sapiens_hsa053100.99472309
40Rheumatoid arthritis_Homo sapiens_hsa053230.99387562
41Acute myeloid leukemia_Homo sapiens_hsa052210.99310621
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.92504187
43Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.91598826
44Hepatitis C_Homo sapiens_hsa051600.89794336
45Phagosome_Homo sapiens_hsa041450.88734828
46Tuberculosis_Homo sapiens_hsa051520.87589436
47SNARE interactions in vesicular transport_Homo sapiens_hsa041300.87363974
48HTLV-I infection_Homo sapiens_hsa051660.85207156
49Epstein-Barr virus infection_Homo sapiens_hsa051690.80940873
50Salmonella infection_Homo sapiens_hsa051320.78856392
51Pertussis_Homo sapiens_hsa051330.78553671
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77301117
53Pancreatic cancer_Homo sapiens_hsa052120.76104847
54Platelet activation_Homo sapiens_hsa046110.71633329
55Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69820263
56Ribosome_Homo sapiens_hsa030100.67756500
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66433520
58Prolactin signaling pathway_Homo sapiens_hsa049170.65802936
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65172326
60Linoleic acid metabolism_Homo sapiens_hsa005910.64103716
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.63127976
62Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.57752231
63Viral carcinogenesis_Homo sapiens_hsa052030.57690254
64Colorectal cancer_Homo sapiens_hsa052100.56656755
65p53 signaling pathway_Homo sapiens_hsa041150.56132539
66VEGF signaling pathway_Homo sapiens_hsa043700.52831015
67Type II diabetes mellitus_Homo sapiens_hsa049300.49407366
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49194978
69Chronic myeloid leukemia_Homo sapiens_hsa052200.48639539
70Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48492664
71Dorso-ventral axis formation_Homo sapiens_hsa043200.47846459
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.46565585
73Arachidonic acid metabolism_Homo sapiens_hsa005900.46335879
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.45638847
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45123324
76African trypanosomiasis_Homo sapiens_hsa051430.44924263
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.43479387
78Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42883520
79Renal cell carcinoma_Homo sapiens_hsa052110.42817383
80Thyroid cancer_Homo sapiens_hsa052160.42770634
81Olfactory transduction_Homo sapiens_hsa047400.42387153
82Regulation of actin cytoskeleton_Homo sapiens_hsa048100.42131885
83Notch signaling pathway_Homo sapiens_hsa043300.39868731
84Serotonergic synapse_Homo sapiens_hsa047260.39541458
85Long-term depression_Homo sapiens_hsa047300.38314441
86Glycerolipid metabolism_Homo sapiens_hsa005610.37770233
87Endocytosis_Homo sapiens_hsa041440.37586885
88Ras signaling pathway_Homo sapiens_hsa040140.37356128
89FoxO signaling pathway_Homo sapiens_hsa040680.37199115
90Nitrogen metabolism_Homo sapiens_hsa009100.35635982
91Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.35339081
92Morphine addiction_Homo sapiens_hsa050320.35296908
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.34970711
94Small cell lung cancer_Homo sapiens_hsa052220.34613753
95RNA degradation_Homo sapiens_hsa030180.34082701
96Cholinergic synapse_Homo sapiens_hsa047250.33786159
97Phototransduction_Homo sapiens_hsa047440.33716890
98Phosphatidylinositol signaling system_Homo sapiens_hsa040700.32377498
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.30532862
100Proteasome_Homo sapiens_hsa030500.28772866
101Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.28607916
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.27435703
103Adherens junction_Homo sapiens_hsa045200.25660080
104Oxytocin signaling pathway_Homo sapiens_hsa049210.24861844
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.24671593
106Inositol phosphate metabolism_Homo sapiens_hsa005620.24621127
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.24529164
108Non-small cell lung cancer_Homo sapiens_hsa052230.24398481
109Spliceosome_Homo sapiens_hsa030400.22747382
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.21218544
111Base excision repair_Homo sapiens_hsa034100.18263710
112Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.17425903
113MAPK signaling pathway_Homo sapiens_hsa040100.17119602
114Prostate cancer_Homo sapiens_hsa052150.14667924
115Other glycan degradation_Homo sapiens_hsa005110.12510629
116Rap1 signaling pathway_Homo sapiens_hsa040150.10771036
117Amoebiasis_Homo sapiens_hsa051460.10595065
118Lysosome_Homo sapiens_hsa041420.08950246
119Endometrial cancer_Homo sapiens_hsa052130.08821482
120DNA replication_Homo sapiens_hsa030300.08819072
121Nucleotide excision repair_Homo sapiens_hsa034200.07359389
122HIF-1 signaling pathway_Homo sapiens_hsa040660.05986839
123Pathways in cancer_Homo sapiens_hsa052000.04689082
124Choline metabolism in cancer_Homo sapiens_hsa052310.04133198
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.03273234
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.02324254
127MicroRNAs in cancer_Homo sapiens_hsa052060.02000940
128Insulin resistance_Homo sapiens_hsa049310.01453622
129Systemic lupus erythematosus_Homo sapiens_hsa05322-0.0017396
130Non-homologous end-joining_Homo sapiens_hsa03450-0.0004878

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