CD300A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)6.77344960
2negative regulation of cell killing (GO:0031342)6.77344960
3modulation by organism of defense response of other organism involved in symbiotic interaction (GO:06.73593258
4positive regulation by organism of defense response of other organism involved in symbiotic interact6.73593258
5modulation by symbiont of host immune response (GO:0052553)6.73593258
6positive regulation by symbiont of host defense response (GO:0052509)6.73593258
7modulation by symbiont of host defense response (GO:0052031)6.73593258
8modulation by organism of immune response of other organism involved in symbiotic interaction (GO:006.73593258
9antigen processing and presentation of endogenous antigen (GO:0019883)5.92400656
10antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.92167435
11neutrophil activation involved in immune response (GO:0002283)5.79748172
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.43454064
13regulation of interferon-beta biosynthetic process (GO:0045357)5.40761019
14antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.31629063
15detection of bacterium (GO:0016045)4.97630473
16macrophage activation involved in immune response (GO:0002281)4.90354239
17regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.89125373
18response to peptidoglycan (GO:0032494)4.83011654
19response to host immune response (GO:0052572)4.73665775
20response to immune response of other organism involved in symbiotic interaction (GO:0052564)4.73665775
21respiratory burst (GO:0045730)4.61914856
22positive regulation of interleukin-8 biosynthetic process (GO:0045416)4.57994225
23microglial cell activation (GO:0001774)4.54081551
24positive regulation of antigen processing and presentation (GO:0002579)4.51508510
25regulation of gamma-delta T cell activation (GO:0046643)4.42296341
26immunoglobulin mediated immune response (GO:0016064)4.36613636
27neutrophil mediated immunity (GO:0002446)4.33208099
28detection of molecule of bacterial origin (GO:0032490)4.29156616
29neutrophil activation (GO:0042119)4.26548217
30response to host (GO:0075136)4.26459395
31response to host defenses (GO:0052200)4.26459395
32response to defenses of other organism involved in symbiotic interaction (GO:0052173)4.26459395
33negative regulation of lymphocyte mediated immunity (GO:0002707)4.24960149
34response to interleukin-15 (GO:0070672)4.10776649
35positive regulation of interferon-alpha production (GO:0032727)4.10082310
36granulocyte activation (GO:0036230)4.09447731
37macrophage activation (GO:0042116)4.08969320
38regulation of antigen processing and presentation (GO:0002577)4.07295743
39* regulation of B cell receptor signaling pathway (GO:0050855)4.03936988
40positive regulation of mast cell activation (GO:0033005)4.02277174
41myeloid cell activation involved in immune response (GO:0002275)3.99408470
42cellular response to interleukin-15 (GO:0071350)3.97909344
43regulation of gamma-delta T cell differentiation (GO:0045586)3.89739778
44cellular extravasation (GO:0045123)3.89141305
45regulation of interferon-alpha production (GO:0032647)3.88045879
46superoxide anion generation (GO:0042554)3.81277176
47* negative regulation of leukocyte mediated immunity (GO:0002704)3.79546233
48* regulation of mast cell activation (GO:0033003)3.75762839
49type I interferon signaling pathway (GO:0060337)3.73882011
50cellular response to type I interferon (GO:0071357)3.73882011
51daunorubicin metabolic process (GO:0044597)3.72531567
52polyketide metabolic process (GO:0030638)3.72531567
53doxorubicin metabolic process (GO:0044598)3.72531567
54response to type I interferon (GO:0034340)3.72491943
55negative T cell selection (GO:0043383)3.72421611
56leukocyte migration involved in inflammatory response (GO:0002523)3.71211593
57positive thymic T cell selection (GO:0045059)3.70250289
58production of molecular mediator involved in inflammatory response (GO:0002532)3.66998543
59negative regulation of granulocyte differentiation (GO:0030853)3.66441820
60negative thymic T cell selection (GO:0045060)3.64637693
61pinocytosis (GO:0006907)3.63871091
62negative regulation of T cell mediated immunity (GO:0002710)3.63327863
63* regulation of mast cell degranulation (GO:0043304)3.58568006
64T cell migration (GO:0072678)3.54640080
65regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.53463299
66regulation of natural killer cell mediated immunity (GO:0002715)3.53463299
67positive regulation of cellular amide metabolic process (GO:0034250)3.52514884
68positive regulation of mast cell activation involved in immune response (GO:0033008)3.52381833
69positive regulation of mast cell degranulation (GO:0043306)3.52381833
70positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.51995613
71antigen processing and presentation via MHC class Ib (GO:0002475)3.49182361
72regulation of dendritic cell antigen processing and presentation (GO:0002604)3.48846007
73interferon-gamma-mediated signaling pathway (GO:0060333)3.46731019
74positive regulation of gamma-delta T cell activation (GO:0046645)3.44545247
75regulation of T cell mediated cytotoxicity (GO:0001914)3.42947456
76regulation of interleukin-8 biosynthetic process (GO:0045414)3.40051270
77positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.38583310
78* regulation of mast cell activation involved in immune response (GO:0033006)3.38223344
79leukocyte aggregation (GO:0070486)3.34229581
80detection of external biotic stimulus (GO:0098581)3.33853245
81positive regulation of B cell differentiation (GO:0045579)3.32613513
82regulation of T cell tolerance induction (GO:0002664)3.31582788
83positive regulation of T cell mediated cytotoxicity (GO:0001916)3.31186506
84myeloid leukocyte mediated immunity (GO:0002444)3.28271645
85negative regulation of innate immune response (GO:0045824)3.26040771
86response to muramyl dipeptide (GO:0032495)3.24729732
87positive T cell selection (GO:0043368)3.24596010
88regulation of tolerance induction (GO:0002643)3.19640604
89myeloid leukocyte activation (GO:0002274)3.19083344
90regulation of alpha-beta T cell proliferation (GO:0046640)3.15721905
91negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.15617564
92G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)3.12701176
93B cell mediated immunity (GO:0019724)3.12349040
94defense response to protozoan (GO:0042832)3.11189216
95detection of other organism (GO:0098543)3.09693414
96regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.09349899
97T cell selection (GO:0045058)3.08234531
98germinal center formation (GO:0002467)3.07576850
99lipopolysaccharide-mediated signaling pathway (GO:0031663)3.07181466
100positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.02454324
101negative regulation of cytokine production involved in immune response (GO:0002719)3.02420378
102positive regulation of interferon-beta production (GO:0032728)3.00334575
103regulation of leukocyte mediated cytotoxicity (GO:0001910)2.98556099
104regulation of B cell differentiation (GO:0045577)2.95093664
105Arp2/3 complex-mediated actin nucleation (GO:0034314)2.94597709
106detection of biotic stimulus (GO:0009595)2.94478441
107glycosphingolipid catabolic process (GO:0046479)2.93920990
108leukocyte degranulation (GO:0043299)2.93702318
109negative regulation of type 2 immune response (GO:0002829)2.93660636
110mast cell activation (GO:0045576)2.92924314
111thymic T cell selection (GO:0045061)2.90800034
112leukocyte mediated cytotoxicity (GO:0001909)2.90646418
113activated T cell proliferation (GO:0050798)2.89775422
114myeloid dendritic cell activation (GO:0001773)2.86617806
115positive regulation of interleukin-1 beta secretion (GO:0050718)2.86019120
116* regulation of myeloid leukocyte mediated immunity (GO:0002886)2.84857114
117I-kappaB phosphorylation (GO:0007252)2.84280150
118dendritic cell migration (GO:0036336)2.84064814
119negative regulation of interleukin-12 production (GO:0032695)2.82819627
120positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.82281970
121negative regulation of interleukin-17 production (GO:0032700)2.80589830
122positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.80556520
123neutrophil chemotaxis (GO:0030593)2.80071793
124positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.79035854
125regulation of interleukin-6 biosynthetic process (GO:0045408)2.78445270
126regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.78188902
127leukotriene metabolic process (GO:0006691)2.77795014
128B cell receptor signaling pathway (GO:0050853)2.77769122
129* regulation of leukocyte degranulation (GO:0043300)2.77484590
130cellular response to interferon-beta (GO:0035458)2.76352646
131reactive oxygen species biosynthetic process (GO:1903409)2.75375753
132positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.74960342
133response to protozoan (GO:0001562)2.74681382
134dendritic cell chemotaxis (GO:0002407)2.71746947
135neutrophil migration (GO:1990266)2.70622785
136regulation of mononuclear cell migration (GO:0071675)2.70302067
137response to fungus (GO:0009620)2.69334403
138ceramide catabolic process (GO:0046514)2.68922309
139positive regulation of T cell migration (GO:2000406)2.67828060
140adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.67532175
141interferon-gamma production (GO:0032609)2.67496743
142* negative regulation of mast cell activation (GO:0033004)2.65235348

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_21731497_ChIP-ChIP_J774_Mouse6.81669731
2BP1_19119308_ChIP-ChIP_Hs578T_Human6.68263798
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.70864501
4* IRF8_27001747_Chip-Seq_BMDM_Mouse4.59205634
5* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse4.52052919
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.93560600
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.71844376
8* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.65357950
9* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.56767665
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.22317970
11MYB_21317192_ChIP-Seq_ERMYB_Mouse3.11948148
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.04860549
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.01244977
14SCL_19346495_ChIP-Seq_HPC-7_Human2.87665128
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.72564389
16* SPI1_23547873_ChIP-Seq_NB4_Human2.72522928
17STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.67982542
18E2F7_22180533_ChIP-Seq_HELA_Human2.45597710
19MYC_22102868_ChIP-Seq_BL_Human2.40619813
20RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.35987481
21BRD4_27068464_Chip-Seq_AML-cells_Mouse2.29085354
22STAT4_19710469_ChIP-ChIP_TH1__Mouse2.22208369
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18973382
24* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.05076135
25FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.02799099
26PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse2.02542585
27MEIS1_20887958_ChIP-Seq_HPC-7_Mouse2.01917839
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.94252589
29PU_27001747_Chip-Seq_BMDM_Mouse1.92644634
30LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.92140072
31PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.89467593
32* RUNX1_22412390_ChIP-Seq_EML_Mouse1.84879917
33* SPI1_23127762_ChIP-Seq_K562_Human1.84754991
34* MAF_26560356_Chip-Seq_TH2_Human1.81764284
35* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.77954949
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.77737412
37RUNX_20019798_ChIP-Seq_JUKART_Human1.75920983
38VDR_24787735_ChIP-Seq_THP-1_Human1.74415467
39TCF7_22412390_ChIP-Seq_EML_Mouse1.74247947
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.72077729
41* CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.71343260
42* MYB_26560356_Chip-Seq_TH2_Human1.70918396
43VDR_24763502_ChIP-Seq_THP-1_Human1.69795556
44RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.68992618
45FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.65337799
46* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.64970427
47ELF1_17652178_ChIP-ChIP_JURKAT_Human1.64222538
48CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64022103
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.59615370
50* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.55289511
51KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.48875090
52CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.47413376
53* KDM2B_26808549_Chip-Seq_DND41_Human1.45893037
54TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.44483110
55GATA1_22025678_ChIP-Seq_K562_Human1.44356433
56VDR_21846776_ChIP-Seq_THP-1_Human1.39751568
57GATA2_21666600_ChIP-Seq_HMVEC_Human1.39543576
58* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.38391486
59STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.37415228
60* MYB_26560356_Chip-Seq_TH1_Human1.36577755
61VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.36320084
62CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.34142133
63GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34098424
64THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.31671898
65GATA2_22383799_ChIP-Seq_G1ME_Mouse1.31167792
66* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.30006748
67GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.29989023
68* BCL6_27268052_Chip-Seq_Bcells_Human1.28202922
69IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27749150
70* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26238262
71LXR_22292898_ChIP-Seq_THP-1_Human1.25525084
72PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22976696
73HOXB4_20404135_ChIP-ChIP_EML_Mouse1.22947289
74MAF_26560356_Chip-Seq_TH1_Human1.19902635
75* GATA3_26560356_Chip-Seq_TH2_Human1.19663856
76GATA1_19941826_ChIP-Seq_K562_Human1.18115855
77PU.1_20513432_ChIP-Seq_Bcells_Mouse1.17513554
78GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.14162088
79* NOTCH1_21737748_ChIP-Seq_TLL_Human1.14021972
80* BCOR_27268052_Chip-Seq_Bcells_Human1.13354158
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.11583402
82ELK3_25401928_ChIP-Seq_HUVEC_Human1.08752563
83NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.06740721
84E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.03978293
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.03818488
86* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03750701
87NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01117130
88GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00597952
89GATA1_19941827_ChIP-Seq_MEL_Mouse0.99556197
90NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.99098009
91TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95846945
92ELF1_20517297_ChIP-Seq_JURKAT_Human0.95634418
93TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.93770544
94TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.93570414
95KDM2B_26808549_Chip-Seq_JURKAT_Human0.92134474
96TFEB_21752829_ChIP-Seq_HELA_Human0.91857582
97* GATA3_27048872_Chip-Seq_THYMUS_Human0.91054714
98CIITA_25753668_ChIP-Seq_RAJI_Human0.89109187
99* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87541640
100PCGF2_27294783_Chip-Seq_ESCs_Mouse0.87515757
101NFE2_27457419_Chip-Seq_LIVER_Mouse0.87452038
102* UTX_26944678_Chip-Seq_JUKART_Human0.87304870
103STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87158830
104GATA2_19941826_ChIP-Seq_K562_Human0.85387046
105SUZ12_27294783_Chip-Seq_NPCs_Mouse0.83337020
106CTCF_27219007_Chip-Seq_ERYTHROID_Human0.81923934
107MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.81672638
108RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.81499197
109SA1_27219007_Chip-Seq_ERYTHROID_Human0.80565860
110PU1_27457419_Chip-Seq_LIVER_Mouse0.79723149
111PCGF2_27294783_Chip-Seq_NPCs_Mouse0.79113105
112FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.78494185
113EZH2_27294783_Chip-Seq_NPCs_Mouse0.76776856
114SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73561157
115STAT3_18555785_Chip-Seq_ESCs_Mouse0.72889782
116SUZ12_18555785_Chip-Seq_ESCs_Mouse0.72118589
117* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70636694
118SPI1_20517297_ChIP-Seq_HL60_Human0.68423303
119NMYC_18555785_Chip-Seq_ESCs_Mouse0.67821990
120RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.67661632
121FLI1_27457419_Chip-Seq_LIVER_Mouse0.67430876
122SMAD_19615063_ChIP-ChIP_OVARY_Human0.65578707
123IGF1R_20145208_ChIP-Seq_DFB_Human0.65239138
124CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.65196715
125RUNX1_27457419_Chip-Seq_LIVER_Mouse0.64141965
126ZFX_18555785_Chip-Seq_ESCs_Mouse0.63775653
127FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.63524346
128P53_22387025_ChIP-Seq_ESCs_Mouse0.62767111
129FOXM1_23109430_ChIP-Seq_U2OS_Human0.62707671

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.47627052
2MP0005058_abnormal_lysosome_morphology3.72953909
3MP0003436_decreased_susceptibility_to3.53163602
4MP0002419_abnormal_innate_immunity3.37380760
5MP0002148_abnormal_hypersensitivity_rea3.15222855
6MP0003172_abnormal_lysosome_physiology2.93192377
7MP0009785_altered_susceptibility_to2.91656502
8MP0005000_abnormal_immune_tolerance2.86705688
9MP0006082_CNS_inflammation2.70754219
10MP0005025_abnormal_response_to2.70480299
11MP0002452_abnormal_antigen_presenting2.63764109
12MP0003303_peritoneal_inflammation2.60133652
13MP0005671_abnormal_response_to2.53947197
14MP0001790_abnormal_immune_system2.52815596
15MP0005387_immune_system_phenotype2.52815596
16MP0001800_abnormal_humoral_immune2.45084976
17MP0005464_abnormal_platelet_physiology2.42459720
18MP0002723_abnormal_immune_serum2.39319682
19MP0003724_increased_susceptibility_to2.37874963
20MP0000569_abnormal_digit_pigmentation2.35832434
21MP0003191_abnormal_cellular_cholesterol2.33569865
22MP0005174_abnormal_tail_pigmentation2.30183506
23MP0001819_abnormal_immune_cell2.25939155
24MP0002420_abnormal_adaptive_immunity2.24361115
25MP0001853_heart_inflammation2.13856226
26MP0000685_abnormal_immune_system2.05630569
27MP0002405_respiratory_system_inflammati1.99110470
28MP0000015_abnormal_ear_pigmentation1.96562255
29MP0003183_abnormal_peptide_metabolism1.93021960
30MP0001533_abnormal_skeleton_physiology1.85272819
31MP0002396_abnormal_hematopoietic_system1.80654305
32MP0004510_myositis1.79495042
33MP0001845_abnormal_inflammatory_respons1.75647192
34MP0000716_abnormal_immune_system1.67248008
35MP0009764_decreased_sensitivity_to1.65741963
36MP0000343_altered_response_to1.62474875
37MP0000465_gastrointestinal_hemorrhage1.59463651
38MP0005310_abnormal_salivary_gland1.58726190
39MP0002398_abnormal_bone_marrow1.58576371
40MP0003866_abnormal_defecation1.56929150
41MP0000689_abnormal_spleen_morphology1.52442092
42MP0009333_abnormal_splenocyte_physiolog1.51740796
43MP0002277_abnormal_respiratory_mucosa1.51535741
44MP0008469_abnormal_protein_level1.48052972
45MP0009840_abnormal_foam_cell1.46573818
46MP0005257_abnormal_intraocular_pressure1.44173174
47MP0010155_abnormal_intestine_physiology1.40179496
48MP0003448_altered_tumor_morphology1.39396339
49MP0002429_abnormal_blood_cell1.37874870
50MP0000858_altered_metastatic_potential1.37494021
51MP0002722_abnormal_immune_system1.33737924
52MP0003690_abnormal_glial_cell1.33348166
53MP0008260_abnormal_autophagy1.31742960
54MP0003075_altered_response_to1.30136103
55MP0009278_abnormal_bone_marrow1.29295999
56MP0002998_abnormal_bone_remodeling1.28691476
57MP0001545_abnormal_hematopoietic_system1.26094018
58MP0005397_hematopoietic_system_phenotyp1.26094018
59MP0004947_skin_inflammation1.23651985
60MP0003806_abnormal_nucleotide_metabolis1.23029913
61MP0002933_joint_inflammation1.17931674
62MP0001851_eye_inflammation1.17299848
63MP0003828_pulmonary_edema1.14387420
64MP0002006_tumorigenesis1.13677375
65MP0000490_abnormal_crypts_of1.12925112
66MP0004782_abnormal_surfactant_physiolog1.11025664
67MP0005075_abnormal_melanosome_morpholog1.10385059
68MP0002166_altered_tumor_susceptibility1.10355264
69MP0005167_abnormal_blood-brain_barrier1.09559915
70MP0001873_stomach_inflammation1.09187946
71MP0008004_abnormal_stomach_pH1.08773573
72MP0010307_abnormal_tumor_latency1.05680627
73MP0002095_abnormal_skin_pigmentation1.04151457
74MP0003300_gastrointestinal_ulcer1.04021652
75MP0004808_abnormal_hematopoietic_stem1.01587785
76MP0005166_decreased_susceptibility_to1.01495212
77MP0005451_abnormal_body_composition0.99714786
78MP0001986_abnormal_taste_sensitivity0.98976416
79MP0002132_abnormal_respiratory_system0.96658336
80MP0005390_skeleton_phenotype0.96353627
81MP0003763_abnormal_thymus_physiology0.95973322
82MP0003656_abnormal_erythrocyte_physiolo0.91967513
83MP0000371_diluted_coat_color0.89321149
84MP0009763_increased_sensitivity_to0.80951914
85MP0003795_abnormal_bone_structure0.76852511
86MP0000703_abnormal_thymus_morphology0.75520519
87MP0004381_abnormal_hair_follicle0.74278965
88MP0003045_fibrosis0.73018910
89MP0010386_abnormal_urinary_bladder0.72561685
90MP0000604_amyloidosis0.70720600
91MP0000249_abnormal_blood_vessel0.70467350
92MP0004883_abnormal_blood_vessel0.66998218
93MP0002254_reproductive_system_inflammat0.65737112
94MP0005164_abnormal_response_to0.64846266
95MP0003566_abnormal_cell_adhesion0.64451006
96MP0002138_abnormal_hepatobiliary_system0.63736722
97MP0004130_abnormal_muscle_cell0.62845238
98MP0002019_abnormal_tumor_incidence0.62689577
99MP0002332_abnormal_exercise_endurance0.62187591
100MP0003646_muscle_fatigue0.62149321
101MP0008007_abnormal_cellular_replicative0.60575328
102MP0001663_abnormal_digestive_system0.60173295
103MP0008874_decreased_physiological_sensi0.60088558
104MP0008058_abnormal_DNA_repair0.58580547
105MP0005319_abnormal_enzyme/_coenzyme0.57074736
106MP0009765_abnormal_xenobiotic_induced0.56981820
107MP0003186_abnormal_redox_activity0.56045753
108MP0006292_abnormal_olfactory_placode0.54987280
109MP0009697_abnormal_copulation0.53494098
110MP0002075_abnormal_coat/hair_pigmentati0.52870400
111MP0005409_darkened_coat_color0.52746470
112MP0003279_aneurysm0.52183712
113MP0002693_abnormal_pancreas_physiology0.51937502
114MP0000920_abnormal_myelination0.49550759
115MP0005584_abnormal_enzyme/coenzyme_acti0.47509804
116MP0000609_abnormal_liver_physiology0.46780439
117MP0005376_homeostasis/metabolism_phenot0.44695911
118MP0002653_abnormal_ependyma_morphology0.42089505

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)7.21442556
2Recurrent bacterial skin infections (HP:0005406)6.12898151
3Eczematoid dermatitis (HP:0000976)5.75651419
4Vacuolated lymphocytes (HP:0001922)5.23344909
5Recurrent gram-negative bacterial infections (HP:0005420)4.95778117
6Abnormality of macrophages (HP:0004311)4.79360322
7Increased cerebral lipofuscin (HP:0011813)4.63222847
8Systemic lupus erythematosus (HP:0002725)4.57494290
9Abnormality of glycolipid metabolism (HP:0010969)4.40682998
10Abnormality of liposaccharide metabolism (HP:0010968)4.40682998
11Abnormality of glycosphingolipid metabolism (HP:0004343)4.40682998
12Increased neuronal autofluorescent lipopigment (HP:0002074)4.21643526
13Myositis (HP:0100614)4.19821169
14Chronic obstructive pulmonary disease (HP:0006510)4.11603731
15Obstructive lung disease (HP:0006536)4.11603731
16Gastrointestinal infarctions (HP:0005244)3.96517783
17Recurrent skin infections (HP:0001581)3.84423636
18Mediastinal lymphadenopathy (HP:0100721)3.78773954
19Dysostosis multiplex (HP:0000943)3.75642436
20Gingivitis (HP:0000230)3.73597415
21Orchitis (HP:0100796)3.67541609
22Increased IgE level (HP:0003212)3.66391231
23Retrobulbar optic neuritis (HP:0100654)3.62666501
24Optic neuritis (HP:0100653)3.62666501
25T lymphocytopenia (HP:0005403)3.51231945
26Elevated erythrocyte sedimentation rate (HP:0003565)3.48334617
27Abnormality of T cell number (HP:0011839)3.43996445
28Recurrent fungal infections (HP:0002841)3.43085629
29Prostate neoplasm (HP:0100787)3.32528869
30Stomatitis (HP:0010280)3.19009688
31Agnosia (HP:0010524)3.17207486
32Panhypogammaglobulinemia (HP:0003139)3.17195263
33Chest pain (HP:0100749)3.09519255
34Petechiae (HP:0000967)3.07802964
35Abnormality of T cells (HP:0002843)3.06619416
36Increased IgM level (HP:0003496)3.06428763
37Abnormality of mucopolysaccharide metabolism (HP:0011020)3.02761327
38Abnormality of polysaccharide metabolism (HP:0011012)3.02761327
39Abnormality of glycosaminoglycan metabolism (HP:0004371)3.02761327
40Disinhibition (HP:0000734)3.02399010
41Glomerulonephritis (HP:0000099)2.95751912
42Mucopolysacchariduria (HP:0008155)2.95689786
43Urinary glycosaminoglycan excretion (HP:0003541)2.95689786
44Hypochromic anemia (HP:0001931)2.91251339
45Recurrent cutaneous fungal infections (HP:0011370)2.91203937
46Chronic mucocutaneous candidiasis (HP:0002728)2.91203937
47Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.88384765
48Recurrent pneumonia (HP:0006532)2.83336994
49Meningitis (HP:0001287)2.82586210
50Hypochromic microcytic anemia (HP:0004840)2.80086055
51Basal ganglia calcification (HP:0002135)2.78692144
52Spontaneous hematomas (HP:0007420)2.78575561
53Periodontitis (HP:0000704)2.76702440
54Hepatosplenomegaly (HP:0001433)2.70281504
55Lymphopenia (HP:0001888)2.69648491
56Axonal loss (HP:0003447)2.69570562
57Urticaria (HP:0001025)2.66882022
58Anorexia (HP:0002039)2.62998145
59Abnormality of T cell physiology (HP:0011840)2.62191537
60Pulmonary embolism (HP:0002204)2.61870312
61Agammaglobulinemia (HP:0004432)2.60142529
62Vasculitis (HP:0002633)2.59857368
63Chronic otitis media (HP:0000389)2.56579316
64Abnormality of the prostate (HP:0008775)2.56469975
65Abnormality of cells of the lymphoid lineage (HP:0012140)2.56255787
66Cheilitis (HP:0100825)2.53051439
67Prolonged bleeding time (HP:0003010)2.51900033
68Hypergammaglobulinemia (HP:0010702)2.51574493
69Recurrent viral infections (HP:0004429)2.50604645
70Chromosomal breakage induced by crosslinking agents (HP:0003221)2.48754332
71Episodic fever (HP:0001954)2.48677598
72Pustule (HP:0200039)2.46174617
73Purpura (HP:0000979)2.44729450
74J-shaped sella turcica (HP:0002680)2.44272237
75Autoimmune thrombocytopenia (HP:0001973)2.43694924
76Chromsome breakage (HP:0040012)2.40080512
77Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.40078361
78Cellulitis (HP:0100658)2.37755752
79Pulmonary infiltrates (HP:0002113)2.36956273
80Recurrent bronchitis (HP:0002837)2.35585070
81IgM deficiency (HP:0002850)2.33544829
82Osteomyelitis (HP:0002754)2.31333144
83Leukocytosis (HP:0001974)2.29465189
84Inflammation of the large intestine (HP:0002037)2.29136646
85Recurrent lower respiratory tract infections (HP:0002783)2.26915401
86Gingival bleeding (HP:0000225)2.26272163
87Gangrene (HP:0100758)2.26072022
88Keratoconjunctivitis sicca (HP:0001097)2.25056786
89Autoimmune hemolytic anemia (HP:0001890)2.22922677
90Microcytic anemia (HP:0001935)2.21839119
91Hemoptysis (HP:0002105)2.21411740
92Joint hemorrhage (HP:0005261)2.20274024
93Loss of speech (HP:0002371)2.18536398
94Pathologic fracture (HP:0002756)2.18467788
95Abnormality of eosinophils (HP:0001879)2.18383919
96Increased serum ferritin (HP:0003281)2.17329354
97Epistaxis (HP:0000421)2.14943045
98Gastrointestinal stroma tumor (HP:0100723)2.14347993
99Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.13387616
100Thoracic kyphosis (HP:0002942)2.13026464
101Amyloidosis (HP:0011034)2.12524624
102Eosinophilia (HP:0001880)2.09106954
103Recurrent sinusitis (HP:0011108)2.09089642
104Albinism (HP:0001022)2.07198455
105IgG deficiency (HP:0004315)2.05264269
106Abnormality of the endocardium (HP:0004306)2.04886711
107Keratoconjunctivitis (HP:0001096)2.04831850
108Peritonitis (HP:0002586)2.04280668
109Abnormality of iron homeostasis (HP:0011031)2.02152269
110Gastrointestinal inflammation (HP:0004386)2.00489131
111Hematochezia (HP:0002573)2.00089548
112Abnormality of the vasculature of the conjunctiva (HP:0008054)1.99846665
113Abnormal delayed hypersensitivity skin test (HP:0002963)1.99459693
114Skin ulcer (HP:0200042)1.99317028
115Interstitial pulmonary disease (HP:0006530)1.99237966
116Thick nail (HP:0001805)1.98084640
117Colitis (HP:0002583)1.98015083
118Malnutrition (HP:0004395)1.97665332
119Encephalitis (HP:0002383)1.97387053
120Polyneuropathy (HP:0001271)1.96500752
121Restrictive lung disease (HP:0002091)1.96428822
122Bone pain (HP:0002653)1.95725002
123Granulocytopenia (HP:0001913)1.95212231
124Arthralgia (HP:0002829)1.94962978
125Acute hepatic failure (HP:0006554)1.94612311
126Abnormality of the peritoneum (HP:0002585)1.93747612
127Arterial thrombosis (HP:0004420)1.92789373
128Upper motor neuron abnormality (HP:0002127)1.91162239
129Myocardial infarction (HP:0001658)1.86191556
130Glomerulopathy (HP:0100820)1.84368717
131Reduced antithrombin III activity (HP:0001976)1.79109398
132Keratitis (HP:0000491)1.76964495
133Nephritis (HP:0000123)1.76755395
134Clubbing of toes (HP:0100760)1.74850422
135Abnormality of the pleura (HP:0002103)1.73929314
136Spondylolisthesis (HP:0003302)1.71788965
137Chronic diarrhea (HP:0002028)1.71269322
138Duplicated collecting system (HP:0000081)1.71090583
139Abnormality of the thoracic spine (HP:0100711)1.70839613
140Sepsis (HP:0100806)1.69692488

Predicted kinase interactions (KEA)

RankGene SetZ-score
1IRAK44.32265161
2IRAK33.76480102
3BLK3.43752003
4KIT3.16142952
5MAP3K143.03074070
6TGFBR22.93524046
7TXK2.59324632
8RIPK42.58287025
9MAP4K12.38479220
10TYK22.32261119
11TBK12.27580031
12TEC2.21863574
13GRK62.12169656
14CSF1R1.96488033
15SIK31.91204678
16IKBKB1.89996869
17MAP3K111.85972086
18BTK1.83787339
19TAOK31.80102977
20IKBKE1.74854932
21GRK71.71325903
22CLK11.68713400
23FES1.56271978
24ZAK1.54475371
25EIF2AK21.49040995
26JAK31.45989080
27TESK21.44867558
28ZAP701.44845286
29SYK1.44071764
30MAP2K31.43163936
31HCK1.43160334
32LYN1.36306413
33CDC42BPA1.35316805
34TAOK11.24922292
35NEK91.22670845
36CSK1.18107972
37TRPM71.16169778
38PIM21.15926464
39SIK21.15751461
40JAK11.15094712
41STK101.14819496
42NME21.11377276
43ITK1.06498669
44STK161.06337426
45LCK1.06102267
46MAP3K11.03485290
47KDR1.03362853
48BMPR1B1.03250220
49PRKD21.00527189
50TRIB31.00042531
51ADRBK20.99978987
52YES10.98153685
53MATK0.97097494
54CAMK1D0.95564380
55MARK30.95279183
56CHUK0.94611766
57PIM10.94153295
58MAP3K130.92119451
59FGR0.89897998
60IRAK10.89810317
61PTK60.89737058
62RPS6KA40.83482631
63BMPR20.82777729
64ERN10.82377733
65PDK10.80664883
66CAMKK20.77973501
67CDK80.77527489
68PRPF4B0.76487892
69PIK3CG0.75763293
70PAK40.75385198
71PRKCQ0.73435672
72IRAK20.71611105
73MAP3K120.70965492
74MAP3K30.69941239
75PRKCD0.69820332
76TNK20.68739290
77LIMK10.68544850
78CDK190.68165611
79STK40.67577740
80JAK20.65106385
81PDPK10.64632025
82CAMKK10.64538069
83FYN0.63911686
84PBK0.63493551
85MAPK120.61874415
86GRK10.61422937
87VRK10.61040392
88PTK2B0.60929471
89KSR20.60396655
90MAPK70.60307818
91MARK20.58871919
92BCKDK0.57834217
93NLK0.57330138
94PLK40.56623560
95EPHB10.54793112
96ERBB30.54404251
97LRRK20.53882307
98TNIK0.52066963
99ABL10.51895356
100MAP3K70.50274517
101STK110.50145087
102EIF2AK30.49311656
103TAOK20.46502779
104MAPKAPK20.45857660
105RPS6KA60.44441739
106MKNK20.44239683
107ATR0.43947212
108PRKCH0.43382887
109EIF2AK10.41807976
110HIPK20.41654657
111MAP3K50.41625137
112MAP3K60.41107043
113MAPK110.41040503
114CDK40.40492992
115NUAK10.40241483
116STK240.39899600
117MAP2K60.39219395
118SMG10.38098271
119FGFR30.37600839
120CAMK1G0.37483439
121CASK0.36999078
122RPS6KL10.36869373
123RPS6KC10.36869373
124SGK20.36217998
125DYRK1B0.35601328
126BRD40.35475252
127DAPK20.35257397
128EGFR0.34574308
129ABL20.33867850
130MOS0.33099672
131SRPK10.31783819
132INSRR0.31715586
133EPHA30.31317728
134MAP2K20.31302254
135FGFR40.30903291
136FLT30.30579193
137TLK10.27208432
138MAPK40.26440464
139CDK90.25965871
140MELK0.22068210
141PRKG20.21404594

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosaminoglycan degradation_Homo sapiens_hsa005313.29401016
2Other glycan degradation_Homo sapiens_hsa005113.28406316
3Staphylococcus aureus infection_Homo sapiens_hsa051503.22304458
4Leishmaniasis_Homo sapiens_hsa051402.99571648
5Lysosome_Homo sapiens_hsa041422.80554215
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.41928729
7NF-kappa B signaling pathway_Homo sapiens_hsa040642.34893007
8Osteoclast differentiation_Homo sapiens_hsa043802.33610654
9Pertussis_Homo sapiens_hsa051332.10291862
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.08716975
11Tuberculosis_Homo sapiens_hsa051522.05824629
12Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.99748130
13Measles_Homo sapiens_hsa051621.84180268
14Phagosome_Homo sapiens_hsa041451.82182847
15Legionellosis_Homo sapiens_hsa051341.79401002
16Intestinal immune network for IgA production_Homo sapiens_hsa046721.78924936
17Malaria_Homo sapiens_hsa051441.76406308
18Hematopoietic cell lineage_Homo sapiens_hsa046401.72683740
19Rheumatoid arthritis_Homo sapiens_hsa053231.72230756
20Graft-versus-host disease_Homo sapiens_hsa053321.71971391
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.69115060
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.67352609
23Asthma_Homo sapiens_hsa053101.63674444
24Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.60140290
25B cell receptor signaling pathway_Homo sapiens_hsa046621.59356317
26Allograft rejection_Homo sapiens_hsa053301.58208481
27Antigen processing and presentation_Homo sapiens_hsa046121.54417708
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.51666303
29Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.45560081
30Influenza A_Homo sapiens_hsa051641.41630814
31Primary immunodeficiency_Homo sapiens_hsa053401.34424528
32Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.33659083
33Herpes simplex infection_Homo sapiens_hsa051681.32120271
34Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31986064
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.29042111
36Salmonella infection_Homo sapiens_hsa051321.28340375
37Apoptosis_Homo sapiens_hsa042101.25523568
38Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.20436697
39Toxoplasmosis_Homo sapiens_hsa051451.20385101
40Sphingolipid metabolism_Homo sapiens_hsa006001.19348740
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15609141
42Jak-STAT signaling pathway_Homo sapiens_hsa046301.15170947
43TNF signaling pathway_Homo sapiens_hsa046681.14047675
44Chemokine signaling pathway_Homo sapiens_hsa040621.13844949
45SNARE interactions in vesicular transport_Homo sapiens_hsa041301.10970248
46Shigellosis_Homo sapiens_hsa051311.05067792
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.02087620
48Hepatitis B_Homo sapiens_hsa051610.98118559
49Homologous recombination_Homo sapiens_hsa034400.97532402
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.97267288
51Autoimmune thyroid disease_Homo sapiens_hsa053200.95227517
52Caffeine metabolism_Homo sapiens_hsa002320.94550649
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.91045063
54Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86272605
55Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.85450991
56Non-small cell lung cancer_Homo sapiens_hsa052230.85096603
57DNA replication_Homo sapiens_hsa030300.84014007
58Fanconi anemia pathway_Homo sapiens_hsa034600.83433930
59Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81571760
60African trypanosomiasis_Homo sapiens_hsa051430.80148833
61Complement and coagulation cascades_Homo sapiens_hsa046100.79874176
62Renin-angiotensin system_Homo sapiens_hsa046140.79181514
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.78997266
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.78411664
65Hepatitis C_Homo sapiens_hsa051600.75137798
66Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.72991516
67Acute myeloid leukemia_Homo sapiens_hsa052210.71801248
68T cell receptor signaling pathway_Homo sapiens_hsa046600.64768928
69Arachidonic acid metabolism_Homo sapiens_hsa005900.62528878
70Pancreatic cancer_Homo sapiens_hsa052120.62178373
71VEGF signaling pathway_Homo sapiens_hsa043700.62158640
72Base excision repair_Homo sapiens_hsa034100.59801108
73Platelet activation_Homo sapiens_hsa046110.57962003
74Non-homologous end-joining_Homo sapiens_hsa034500.57641393
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57145421
76Viral myocarditis_Homo sapiens_hsa054160.56281902
77Epstein-Barr virus infection_Homo sapiens_hsa051690.55553465
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52660421
79Type I diabetes mellitus_Homo sapiens_hsa049400.50995448
80Mismatch repair_Homo sapiens_hsa034300.50260330
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.49248401
82Chronic myeloid leukemia_Homo sapiens_hsa052200.48785510
83AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.46359771
84ABC transporters_Homo sapiens_hsa020100.45569021
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44964923
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.44801099
87Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44021502
88Renal cell carcinoma_Homo sapiens_hsa052110.41683958
89p53 signaling pathway_Homo sapiens_hsa041150.40735790
90Phospholipase D signaling pathway_Homo sapiens_hsa040720.40382077
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.39737748
92Collecting duct acid secretion_Homo sapiens_hsa049660.38891137
93Notch signaling pathway_Homo sapiens_hsa043300.38643944
94Regulation of autophagy_Homo sapiens_hsa041400.38101198
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37005724
96Amoebiasis_Homo sapiens_hsa051460.36868418
97MAPK signaling pathway_Homo sapiens_hsa040100.36231093
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.35852194
99Mineral absorption_Homo sapiens_hsa049780.34824789
100Systemic lupus erythematosus_Homo sapiens_hsa053220.34440246
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.33440782
102HIF-1 signaling pathway_Homo sapiens_hsa040660.32999920
103Inositol phosphate metabolism_Homo sapiens_hsa005620.32576608
104FoxO signaling pathway_Homo sapiens_hsa040680.30224973
105Viral carcinogenesis_Homo sapiens_hsa052030.30002385
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.28694170
107Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.28458818
108HTLV-I infection_Homo sapiens_hsa051660.28076494
109GnRH signaling pathway_Homo sapiens_hsa049120.27135919
110Rap1 signaling pathway_Homo sapiens_hsa040150.27026354
111Neurotrophin signaling pathway_Homo sapiens_hsa047220.26869943
112Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26471159
113Choline metabolism in cancer_Homo sapiens_hsa052310.26468481
114mTOR signaling pathway_Homo sapiens_hsa041500.25979438
115Insulin resistance_Homo sapiens_hsa049310.24720428
116Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22388988
117N-Glycan biosynthesis_Homo sapiens_hsa005100.22204063
118Small cell lung cancer_Homo sapiens_hsa052220.21836911
119Endocytosis_Homo sapiens_hsa041440.21532175
120Colorectal cancer_Homo sapiens_hsa052100.21245724
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.21216280
122Prolactin signaling pathway_Homo sapiens_hsa049170.20840288
123Pyrimidine metabolism_Homo sapiens_hsa002400.19391959

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