CD7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sequestering of actin monomers (GO:0042989)9.67784003
2barbed-end actin filament capping (GO:0051016)7.84387070
3T cell migration (GO:0072678)7.19182228
4regulation of gamma-delta T cell differentiation (GO:0045586)6.87371208
5negative thymic T cell selection (GO:0045060)6.75972971
6positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)6.62168829
7positive regulation of gamma-delta T cell activation (GO:0046645)6.58082079
8negative T cell selection (GO:0043383)6.57041612
9antigen processing and presentation of endogenous antigen (GO:0019883)6.52212953
10DNA deamination (GO:0045006)6.22350486
11regulation of B cell receptor signaling pathway (GO:0050855)6.13189368
12regulation of gamma-delta T cell activation (GO:0046643)6.05143276
13thymic T cell selection (GO:0045061)6.01852195
14positive thymic T cell selection (GO:0045059)5.96044660
15cellular response to interleukin-15 (GO:0071350)5.92936804
16T cell receptor signaling pathway (GO:0050852)5.88305974
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.61895560
18negative regulation of cell killing (GO:0031342)5.61895560
19leukocyte aggregation (GO:0070486)5.57600191
20mast cell activation (GO:0045576)5.57352220
21regulation of T cell tolerance induction (GO:0002664)5.47765901
22negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)5.43170890
23cellular response to zinc ion (GO:0071294)5.42111586
24T cell costimulation (GO:0031295)5.41686968
25lymphocyte costimulation (GO:0031294)5.32266913
26regulation of antigen receptor-mediated signaling pathway (GO:0050854)5.29445149
27interferon-gamma production (GO:0032609)5.24052786
28antigen receptor-mediated signaling pathway (GO:0050851)5.17264256
29mast cell activation involved in immune response (GO:0002279)5.08543421
30mast cell degranulation (GO:0043303)5.08543421
31regulation of T cell receptor signaling pathway (GO:0050856)5.07781379
32response to interleukin-15 (GO:0070672)5.03782635
33tolerance induction (GO:0002507)5.02005795
34regulation of natural killer cell mediated immunity (GO:0002715)4.95789447
35regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.95789447
36positive regulation of natural killer cell mediated immunity (GO:0002717)4.92217339
37positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)4.92217339
38antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.78940278
39regulation of isotype switching to IgG isotypes (GO:0048302)4.78760899
40T cell selection (GO:0045058)4.64179285
41leukocyte tethering or rolling (GO:0050901)4.61253647
42positive T cell selection (GO:0043368)4.60530733
43activated T cell proliferation (GO:0050798)4.38667037
44positive regulation of tolerance induction (GO:0002645)4.35331438
45positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.34279178
46signal complex assembly (GO:0007172)4.31316489
47negative regulation of lymphocyte mediated immunity (GO:0002707)4.29434001
48positive regulation of leukocyte mediated cytotoxicity (GO:0001912)4.24919240
49regulation of leukocyte mediated cytotoxicity (GO:0001910)4.23688118
50leukocyte cell-cell adhesion (GO:0007159)4.22206279
51B cell receptor signaling pathway (GO:0050853)4.18024579
52positive regulation of alpha-beta T cell proliferation (GO:0046641)4.16704583
53negative regulation of T cell receptor signaling pathway (GO:0050860)4.09554363
54antigen processing and presentation via MHC class Ib (GO:0002475)4.08176361
55negative regulation of phagocytosis (GO:0050765)3.99802004
56chemokine-mediated signaling pathway (GO:0070098)3.97135923
57positive regulation of lamellipodium assembly (GO:0010592)3.95455803
58negative regulation of T cell mediated immunity (GO:0002710)3.92323652
59regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.91441740
60negative regulation of leukocyte mediated immunity (GO:0002704)3.90885136
61regulation of response to interferon-gamma (GO:0060330)3.90675915
62heterotypic cell-cell adhesion (GO:0034113)3.87795269
63detection of bacterium (GO:0016045)3.85208305
64lymphocyte migration (GO:0072676)3.81709185
65regulation of tolerance induction (GO:0002643)3.80238814
66positive regulation of B cell differentiation (GO:0045579)3.79462618
67positive regulation by symbiont of host defense response (GO:0052509)3.76056072
68modulation by symbiont of host defense response (GO:0052031)3.76056072
69modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.76056072
70modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.76056072
71positive regulation by organism of defense response of other organism involved in symbiotic interact3.76056072
72modulation by symbiont of host immune response (GO:0052553)3.76056072
73positive regulation of granulocyte differentiation (GO:0030854)3.73618413
74regulation of regulatory T cell differentiation (GO:0045589)3.73377423
75viral genome replication (GO:0019079)3.72892257
76detection of other organism (GO:0098543)3.70313478
77neutrophil activation involved in immune response (GO:0002283)3.68479515
78positive regulation of cell killing (GO:0031343)3.68130815
79negative regulation of type 2 immune response (GO:0002829)3.68040354
80regulation of cell killing (GO:0031341)3.67487678
81positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.61620879
82immune response-activating cell surface receptor signaling pathway (GO:0002429)3.59547994
83negative regulation of actin filament polymerization (GO:0030837)3.56457252
84regulation of alpha-beta T cell proliferation (GO:0046640)3.55474195
85Peyers patch development (GO:0048541)3.48334838
86mucosal-associated lymphoid tissue development (GO:0048537)3.48334838
87positive regulation of T-helper 1 type immune response (GO:0002827)3.47852489
88negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.46649095
89regulation of T cell mediated cytotoxicity (GO:0001914)3.44003490
90response to muramyl dipeptide (GO:0032495)3.42759457
91positive regulation of T cell differentiation in thymus (GO:0033089)3.41239048
92regulation of interleukin-2 biosynthetic process (GO:0045076)3.38869900
93cellular response to type I interferon (GO:0071357)3.38564194
94type I interferon signaling pathway (GO:0060337)3.38564194
95negative regulation of interleukin-12 production (GO:0032695)3.37099135
96response to type I interferon (GO:0034340)3.36452353
97negative regulation of erythrocyte differentiation (GO:0045647)3.34029371
98regulation of type I interferon-mediated signaling pathway (GO:0060338)3.29385314
99T cell homeostasis (GO:0043029)3.28430039
100positive regulation of lamellipodium organization (GO:1902745)3.27516183
101regulation of B cell differentiation (GO:0045577)3.25951339
102cellular defense response (GO:0006968)3.25483191
103positive regulation of uterine smooth muscle contraction (GO:0070474)3.25420106
104cellular extravasation (GO:0045123)3.23982996
105membrane raft organization (GO:0031579)3.21302869
106macrophage activation involved in immune response (GO:0002281)3.21299762
107leukocyte degranulation (GO:0043299)3.18854314
108T-helper cell differentiation (GO:0042093)3.16768547
109CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.16768547
110positive regulation of T cell mediated cytotoxicity (GO:0001916)3.14708793
111negative regulation of innate immune response (GO:0045824)3.13366301
112myeloid dendritic cell differentiation (GO:0043011)3.13142113
113regulation of activation of Janus kinase activity (GO:0010533)3.11240032
114immunoglobulin mediated immune response (GO:0016064)3.08491125
115negative regulation of leukocyte chemotaxis (GO:0002689)3.07574117
116NIK/NF-kappaB signaling (GO:0038061)3.05480477
117natural killer cell differentiation (GO:0001779)3.05346079
118regulation of granulocyte differentiation (GO:0030852)3.04309502
119regulation of macrophage chemotaxis (GO:0010758)3.04147488
120protein deneddylation (GO:0000338)3.02632928
121myeloid dendritic cell activation (GO:0001773)3.01980038
122regulation of alpha-beta T cell activation (GO:0046634)3.01254170
123neutrophil activation (GO:0042119)3.01013957
124alpha-beta T cell differentiation (GO:0046632)3.00646989
125positive regulation of interleukin-2 production (GO:0032743)3.00506575
126germinal center formation (GO:0002467)2.98575806
127positive regulation of interleukin-4 production (GO:0032753)2.96755963
128antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.96383907
129antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.96383907
130positive regulation of immune response to tumor cell (GO:0002839)2.94485669
131regulation of immune response to tumor cell (GO:0002837)2.94485669
132regulation of response to tumor cell (GO:0002834)2.94485669
133positive regulation of response to tumor cell (GO:0002836)2.94485669
134oxidative demethylation (GO:0070989)2.94452383
135alpha-beta T cell differentiation involved in immune response (GO:0002293)2.94303144
136alpha-beta T cell activation involved in immune response (GO:0002287)2.94303144
137T cell differentiation involved in immune response (GO:0002292)2.94303144
138* T cell activation (GO:0042110)2.93226097
139positive regulation of T cell differentiation (GO:0045582)2.93087424
140lymphocyte homeostasis (GO:0002260)2.93004738
141positive regulation of T cell activation (GO:0050870)2.92519988
142negative regulation of cytokine production involved in immune response (GO:0002719)2.89708018
143negative regulation of T-helper cell differentiation (GO:0045623)2.89104023
144negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.89104023
145negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.87893893
146negative regulation of alpha-beta T cell activation (GO:0046636)2.87345240
147defense response to protozoan (GO:0042832)2.86408646
148myeloid cell activation involved in immune response (GO:0002275)2.86334220
149gap junction assembly (GO:0016264)11.2019793

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.10489092
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.05439305
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.24545724
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.05417393
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.82590615
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.78270038
7STAT4_19710469_ChIP-ChIP_TH1__Mouse3.60480672
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.38123338
9RUNX1_20887958_ChIP-Seq_HPC-7_Mouse3.20617749
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.14666821
11SPI1_22096565_ChIP-ChIP_GC-B_Mouse3.09424039
12RUNX_20019798_ChIP-Seq_JUKART_Human3.07866399
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.96698067
14MAF_26560356_Chip-Seq_TH1_Human2.87546954
15UTX_26944678_Chip-Seq_JUKART_Human2.72690850
16MYB_26560356_Chip-Seq_TH2_Human2.70006521
17NOTCH1_21737748_ChIP-Seq_TLL_Human2.66980851
18MYC_22102868_ChIP-Seq_BL_Human2.63544080
19FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.60521360
20STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.52506718
21MYB_26560356_Chip-Seq_TH1_Human2.45414192
22CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.33928106
23FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.30830802
24BP1_19119308_ChIP-ChIP_Hs578T_Human2.28100918
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.26213006
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.17741190
27* RUNX1_22412390_ChIP-Seq_EML_Mouse2.15017588
28E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.03565909
29SPI1_23547873_ChIP-Seq_NB4_Human1.96194136
30SCL_19346495_ChIP-Seq_HPC-7_Human1.96175184
31* MAF_26560356_Chip-Seq_TH2_Human1.90395231
32VDR_24763502_ChIP-Seq_THP-1_Human1.85617284
33LXR_22292898_ChIP-Seq_THP-1_Human1.75607144
34MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.74218956
35CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.72806748
36VDR_21846776_ChIP-Seq_THP-1_Human1.69147733
37GATA3_27048872_Chip-Seq_THYMUS_Human1.64357461
38LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.64024975
39NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.61634171
40* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.57946485
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.51884099
42KDM2B_26808549_Chip-Seq_JURKAT_Human1.51641843
43EGR1_19032775_ChIP-ChIP_M12_Human1.50344320
44NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.49852893
45* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.49607413
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48887431
47GATA3_26560356_Chip-Seq_TH2_Human1.48720735
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.45425741
49SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.44746663
50CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.44436471
51EGR1_19374776_ChIP-ChIP_THP-1_Human1.42661512
52ELF1_17652178_ChIP-ChIP_JURKAT_Human1.40655803
53IRF8_27001747_Chip-Seq_BMDM_Mouse1.40233836
54FLI1_21867929_ChIP-Seq_CD8_Mouse1.39720830
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.39598439
56CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.39116142
57TCF7_22412390_ChIP-Seq_EML_Mouse1.37639543
58* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.37158833
59MYB_21317192_ChIP-Seq_ERMYB_Mouse1.36972603
60* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.36871362
61ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36832491
62TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.36300609
63LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.33475979
64GATA1_19941827_ChIP-Seq_MEL_Mouse1.31822602
65RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.30234821
66ELK3_25401928_ChIP-Seq_HUVEC_Human1.29722190
67CIITA_25753668_ChIP-Seq_RAJI_Human1.26987966
68* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.25284544
69GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.24602810
70GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.24542857
71VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.24164709
72SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human1.22199880
73GATA1_22383799_ChIP-Seq_G1ME_Mouse1.19648442
74BCOR_27268052_Chip-Seq_Bcells_Human1.18520066
75PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.18424837
76BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.16880280
77GATA2_22383799_ChIP-Seq_G1ME_Mouse1.16441173
78SPI1_23127762_ChIP-Seq_K562_Human1.16001314
79GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.13830643
80* KDM2B_26808549_Chip-Seq_DND41_Human1.12621499
81ERG_20887958_ChIP-Seq_HPC-7_Mouse1.11454831
82PHF8_20622854_ChIP-Seq_HELA_Human1.10959034
83RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.10771334
84* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09674664
85SA1_27219007_Chip-Seq_ERYTHROID_Human1.09081243
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.08575968
87THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07950489
88RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.07747914
89PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06848358
90PU_27001747_Chip-Seq_BMDM_Mouse1.04426734
91JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.04155976
92BCL6_27268052_Chip-Seq_Bcells_Human1.03819248
93BRD4_27068464_Chip-Seq_AML-cells_Mouse1.02366556
94STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02199725
95WDR5_24793694_ChIP-Seq_LNCAP_Human1.01960144
96SA1_27219007_Chip-Seq_Bcells_Human1.01818828
97GATA1_19941826_ChIP-Seq_K562_Human1.00525168
98CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00239829
99VDR_24787735_ChIP-Seq_THP-1_Human0.99788356
100FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99415922
101CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99195252
102CTCF_26484167_Chip-Seq_Bcells_Mouse0.98062756
103NCOR1_26117541_ChIP-Seq_K562_Human0.95844212
104SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.95068785
105* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94717032
106VDR_23849224_ChIP-Seq_CD4+_Human0.94716241
107VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.94636867
108IKZF1_21737484_ChIP-ChIP_HCT116_Human0.94272630
109* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93016475
110NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92669988
111GABP_17652178_ChIP-ChIP_JURKAT_Human0.92181252
112* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.91894004
113P68_20966046_ChIP-Seq_HELA_Human0.91437229
114* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90649605
115CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90378664
116SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88277473
117TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87812655
118* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86111455
119* SRY_22984422_ChIP-ChIP_TESTIS_Rat0.84828421
120P300_27268052_Chip-Seq_Bcells_Human0.83215469
121SPI1_20517297_ChIP-Seq_HL60_Human0.82522686
122CTCF_21964334_ChIP-Seq_BJAB-B_Human0.81941799
123GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81850656
124ETS1_21867929_ChIP-Seq_TH2_Mouse0.81075160
125PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.79337680

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.79762541
2MP0003763_abnormal_thymus_physiology5.06939340
3MP0000685_abnormal_immune_system4.26745809
4MP0002933_joint_inflammation3.33960940
5MP0001835_abnormal_antigen_presentation3.33182626
6MP0009785_altered_susceptibility_to3.29267679
7MP0001800_abnormal_humoral_immune3.21430889
8MP0002420_abnormal_adaptive_immunity3.10463710
9MP0001819_abnormal_immune_cell3.06756104
10MP0005000_abnormal_immune_tolerance3.02308658
11MP0002723_abnormal_immune_serum2.95596180
12MP0003724_increased_susceptibility_to2.91650191
13MP0005025_abnormal_response_to2.87444218
14MP0002166_altered_tumor_susceptibility2.84819112
15MP0001790_abnormal_immune_system2.84685540
16MP0005387_immune_system_phenotype2.84685540
17MP0002398_abnormal_bone_marrow2.79792188
18MP0002452_abnormal_antigen_presenting2.70348673
19MP0002405_respiratory_system_inflammati2.56396543
20MP0000716_abnormal_immune_system2.46793192
21MP0004947_skin_inflammation2.34449166
22MP0002722_abnormal_immune_system2.34130854
23MP0006082_CNS_inflammation2.32838088
24MP0002006_tumorigenesis2.32705570
25MP0001873_stomach_inflammation2.32229728
26MP0005075_abnormal_melanosome_morpholog2.27095769
27MP0000689_abnormal_spleen_morphology2.26226882
28MP0005464_abnormal_platelet_physiology2.19416896
29MP0004510_myositis2.13873482
30MP0002419_abnormal_innate_immunity2.07091931
31MP0010155_abnormal_intestine_physiology2.05079376
32* MP0000703_abnormal_thymus_morphology2.01117646
33MP0002429_abnormal_blood_cell1.96246657
34MP0003172_abnormal_lysosome_physiology1.95653055
35MP0010234_abnormal_vibrissa_follicle1.95296858
36MP0003137_abnormal_impulse_conducting1.91287597
37MP0005174_abnormal_tail_pigmentation1.88137611
38MP0009333_abnormal_splenocyte_physiolog1.76240449
39MP0002148_abnormal_hypersensitivity_rea1.73184192
40MP0000015_abnormal_ear_pigmentation1.72843727
41MP0001845_abnormal_inflammatory_respons1.66428097
42MP0000858_altered_metastatic_potential1.61878625
43MP0003123_paternal_imprinting1.61317768
44MP0000465_gastrointestinal_hemorrhage1.45705222
45MP0003866_abnormal_defecation1.40966613
46MP0003436_decreased_susceptibility_to1.39750885
47MP0002132_abnormal_respiratory_system1.37329154
48MP0000343_altered_response_to1.30523847
49MP0001853_heart_inflammation1.30123771
50MP0002009_preneoplasia1.29663365
51MP0002909_abnormal_adrenal_gland1.23684026
52MP0003191_abnormal_cellular_cholesterol1.23151234
53MP0008469_abnormal_protein_level1.18319084
54MP0009278_abnormal_bone_marrow1.14588640
55MP0005451_abnormal_body_composition1.13584053
56MP0000371_diluted_coat_color1.12284043
57MP0000490_abnormal_crypts_of1.11319806
58MP0002277_abnormal_respiratory_mucosa1.10688858
59MP0001851_eye_inflammation1.10166642
60MP0008260_abnormal_autophagy1.02736231
61MP0002019_abnormal_tumor_incidence1.02591933
62MP0003448_altered_tumor_morphology0.96751054
63MP0001663_abnormal_digestive_system0.94708518
64MP0003656_abnormal_erythrocyte_physiolo0.92664503
65MP0004381_abnormal_hair_follicle0.92117770
66MP0005310_abnormal_salivary_gland0.90120815
67MP0003453_abnormal_keratinocyte_physiol0.83664302
68MP0005023_abnormal_wound_healing0.81104334
69MP0008995_early_reproductive_senescence0.80513724
70MP0003828_pulmonary_edema0.80325914
71MP0001986_abnormal_taste_sensitivity0.79988878
72MP0009763_increased_sensitivity_to0.79561854
73MP0002396_abnormal_hematopoietic_system0.78428026
74MP0003183_abnormal_peptide_metabolism0.78296302
75MP0005166_decreased_susceptibility_to0.76172818
76MP0003878_abnormal_ear_physiology0.74454664
77MP0005377_hearing/vestibular/ear_phenot0.74454664
78MP0004808_abnormal_hematopoietic_stem0.74003204
79MP0005390_skeleton_phenotype0.73725659
80MP0001533_abnormal_skeleton_physiology0.73553946
81MP0009840_abnormal_foam_cell0.73318533
82MP0005083_abnormal_biliary_tract0.73196886
83MP0003045_fibrosis0.70685442
84MP0001529_abnormal_vocalization0.70537282
85MP0001545_abnormal_hematopoietic_system0.70017245
86MP0005397_hematopoietic_system_phenotyp0.70017245
87MP0000920_abnormal_myelination0.69036753
88MP0002136_abnormal_kidney_physiology0.66015052
89MP0002998_abnormal_bone_remodeling0.65174374
90MP0003633_abnormal_nervous_system0.64113021
91MP0004883_abnormal_blood_vessel0.63939872
92MP0001348_abnormal_lacrimal_gland0.63486368
93MP0003795_abnormal_bone_structure0.62672704
94MP0003786_premature_aging0.61637178
95MP0000609_abnormal_liver_physiology0.61012666
96MP0005360_urolithiasis0.60749224
97MP0004130_abnormal_muscle_cell0.60381630
98MP0009765_abnormal_xenobiotic_induced0.60279815
99MP0002095_abnormal_skin_pigmentation0.59393784
100MP0003329_amyloid_beta_deposits0.59182892
101MP0009764_decreased_sensitivity_to0.58548744
102MP0001324_abnormal_eye_pigmentation0.58405848
103MP0002254_reproductive_system_inflammat0.58340113
104MP0000249_abnormal_blood_vessel0.58118472
105MP0005381_digestive/alimentary_phenotyp0.56156279
106MP0000639_abnormal_adrenal_gland0.55240920
107MP0002653_abnormal_ependyma_morphology0.55240623
108MP0000604_amyloidosis0.52465515
109MP0003690_abnormal_glial_cell0.50724987
110MP0005085_abnormal_gallbladder_physiolo0.50556287
111MP0003303_peritoneal_inflammation0.49597336
112MP0008057_abnormal_DNA_replication0.49247349
113MP0009643_abnormal_urine_homeostasis0.47575559
114MP0008961_abnormal_basal_metabolism0.47048300
115MP0005645_abnormal_hypothalamus_physiol0.44898709
116MP0003075_altered_response_to0.43910164
117MP0001765_abnormal_ion_homeostasis0.43267708
118MP0004185_abnormal_adipocyte_glucose0.43217423
119MP0000477_abnormal_intestine_morphology0.42122692
120MP0002928_abnormal_bile_duct0.41879263
121MP0005167_abnormal_blood-brain_barrier0.40735594
122MP0005330_cardiomyopathy0.40728881
123MP0002138_abnormal_hepatobiliary_system0.40355495
124MP0001119_abnormal_female_reproductive0.40211866
125MP0002083_premature_death0.40131445
126MP0000613_abnormal_salivary_gland0.39821940
127MP0005076_abnormal_cell_differentiation0.39545094
128MP0003300_gastrointestinal_ulcer0.39406040
129MP0005164_abnormal_response_to0.38451930
130MP0008873_increased_physiological_sensi0.37611186
131MP0005171_absent_coat_pigmentation0.37017599
132MP0002693_abnormal_pancreas_physiology0.36517057
133MP0009642_abnormal_blood_homeostasis0.35545879
134MP0001243_abnormal_dermal_layer0.35507115
135MP0008877_abnormal_DNA_methylation0.35328235
136MP0005058_abnormal_lysosome_morphology0.34511619

Predicted human phenotypes

RankGene SetZ-score
1Severe combined immunodeficiency (HP:0004430)6.25023980
2Stomatitis (HP:0010280)5.99581679
3Increased IgM level (HP:0003496)5.75442119
4IgM deficiency (HP:0002850)5.75056733
5Combined immunodeficiency (HP:0005387)5.63421422
6Myositis (HP:0100614)5.30907497
7T lymphocytopenia (HP:0005403)5.28464738
8IgG deficiency (HP:0004315)5.26360508
9Elevated erythrocyte sedimentation rate (HP:0003565)5.21015053
10Abnormality of T cell number (HP:0011839)5.05564307
11Recurrent bronchitis (HP:0002837)4.98939491
12Abnormal delayed hypersensitivity skin test (HP:0002963)4.86242534
13Pustule (HP:0200039)4.79039577
14Recurrent abscess formation (HP:0002722)4.78735536
15Abnormality of T cells (HP:0002843)4.58333318
16Eczematoid dermatitis (HP:0000976)4.48591412
17Abnormality of macrophages (HP:0004311)4.46370570
18Recurrent skin infections (HP:0001581)4.11874535
19Increased IgE level (HP:0003212)4.00285592
20Abnormality of T cell physiology (HP:0011840)3.79467861
21Autoimmune hemolytic anemia (HP:0001890)3.71682167
22Thyroiditis (HP:0100646)3.66543706
23Granulocytopenia (HP:0001913)3.66122834
24Distal arthrogryposis (HP:0005684)3.65122281
25Diastasis recti (HP:0001540)3.58982638
26Lymphopenia (HP:0001888)3.55311511
27Retrobulbar optic neuritis (HP:0100654)3.53033008
28Optic neuritis (HP:0100653)3.53033008
29Recurrent cutaneous fungal infections (HP:0011370)3.50799262
30Chronic mucocutaneous candidiasis (HP:0002728)3.50799262
31Recurrent fungal infections (HP:0002841)3.48423134
32Orchitis (HP:0100796)3.46803720
33IgA deficiency (HP:0002720)3.46450570
34Recurrent sinusitis (HP:0011108)3.44344952
35Abnormality of cells of the lymphoid lineage (HP:0012140)3.36263858
36Eosinophilia (HP:0001880)3.27605717
37Hypochromic anemia (HP:0001931)3.27450075
38Decreased activity of mitochondrial respiratory chain (HP:0008972)3.27127387
39Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.27127387
40Gingivitis (HP:0000230)3.24516194
41Hypoplasia of the thymus (HP:0000778)3.21504904
42Spontaneous hematomas (HP:0007420)3.21011240
43Chronic diarrhea (HP:0002028)3.17482914
44Recurrent bacterial skin infections (HP:0005406)3.16643367
45Panhypogammaglobulinemia (HP:0003139)3.12226975
46Amyotrophic lateral sclerosis (HP:0007354)3.09241290
47Recurrent otitis media (HP:0000403)2.95496941
48Albinism (HP:0001022)2.92789440
49Microretrognathia (HP:0000308)2.90223361
50Meningitis (HP:0001287)2.90032447
51Petechiae (HP:0000967)2.86348117
52Agammaglobulinemia (HP:0004432)2.85025849
53Ragged-red muscle fibers (HP:0003200)2.84238232
54Leukocytosis (HP:0001974)2.82739607
55Chest pain (HP:0100749)2.80935780
56Inflammation of the large intestine (HP:0002037)2.78333474
57Abnormality of eosinophils (HP:0001879)2.75385599
58Hypochromic microcytic anemia (HP:0004840)2.71461639
59Bronchitis (HP:0012387)2.65484247
60Severe visual impairment (HP:0001141)2.62973891
61Hematochezia (HP:0002573)2.58051938
62Gastrointestinal inflammation (HP:0004386)2.57703742
63Recurrent gram-negative bacterial infections (HP:0005420)2.56716000
64Hypergammaglobulinemia (HP:0010702)2.56465388
65Cellulitis (HP:0100658)2.56373385
66Urticaria (HP:0001025)2.52957365
67Epistaxis (HP:0000421)2.51346617
68Joint swelling (HP:0001386)2.49920768
69Fragile skin (HP:0001030)2.48223049
70Atrophy/Degeneration involving motor neurons (HP:0007373)2.47196755
71Obstructive lung disease (HP:0006536)2.45876946
72Chronic obstructive pulmonary disease (HP:0006510)2.45876946
73Episodic fever (HP:0001954)2.43405009
74Keratoconjunctivitis sicca (HP:0001097)2.42564653
75Mediastinal lymphadenopathy (HP:0100721)2.41747293
76Spastic tetraparesis (HP:0001285)2.40313165
77Papilloma (HP:0012740)2.40043427
78Verrucae (HP:0200043)2.40043427
79Abnormality of the fingertips (HP:0001211)2.38822899
80Colitis (HP:0002583)2.34148217
81Arterial thrombosis (HP:0004420)2.31160359
82Muscle fiber atrophy (HP:0100295)2.29639969
83Type 2 muscle fiber atrophy (HP:0003554)2.29436584
84Vasculitis (HP:0002633)2.29327011
85Autoimmune thrombocytopenia (HP:0001973)2.29137881
86Abnormality of B cell number (HP:0010975)2.27238948
87B lymphocytopenia (HP:0010976)2.27238948
88Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.26011019
89Pulmonary fibrosis (HP:0002206)2.22104064
90Encephalitis (HP:0002383)2.21365944
91Pulmonary infiltrates (HP:0002113)2.18238107
92Gastrointestinal stroma tumor (HP:0100723)2.15390454
93Keratoconjunctivitis (HP:0001096)2.14873481
94Papilledema (HP:0001085)2.11839996
95Abnormality of the pleura (HP:0002103)2.11228817
96Glomerulopathy (HP:0100820)2.09591478
97Lymphoma (HP:0002665)2.08484548
98Acute hepatic failure (HP:0006554)2.02338125
99Sepsis (HP:0100806)2.01086713
100Increased serum ferritin (HP:0003281)2.00311456
101Purpura (HP:0000979)1.99195864
102Ocular albinism (HP:0001107)1.98288441
103Chronic otitis media (HP:0000389)1.97019069
104Abnormality of the alveolar ridges (HP:0006477)1.96759344
105Stomach cancer (HP:0012126)1.96385587
106Microcytic anemia (HP:0001935)1.96085104
107Hemoptysis (HP:0002105)1.95279343
108Recurrent pneumonia (HP:0006532)1.94772014
109Nasal polyposis (HP:0100582)1.94753129
110Systemic lupus erythematosus (HP:0002725)1.93327457
111Slow saccadic eye movements (HP:0000514)1.93001973
112Osteomyelitis (HP:0002754)1.92470816
113Acne (HP:0001061)1.90106240
114Arthralgia (HP:0002829)1.88035055
115Keratitis (HP:0000491)1.87969039
116Premature loss of primary teeth (HP:0006323)1.86382297
117Anorexia (HP:0002039)1.83950730
118Pulmonary embolism (HP:0002204)1.83730226
119Gastrointestinal infarctions (HP:0005244)1.81725931
120Recurrent viral infections (HP:0004429)1.81136383
121Gingival bleeding (HP:0000225)1.79255494
122Skin ulcer (HP:0200042)1.76617754
123Irregular vertebral endplates (HP:0003301)1.71401491
124Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.68400107
125Abnormality of the nasal mucosa (HP:0000433)1.68018882
126Prolonged bleeding time (HP:0003010)1.67228586
127Dyskinesia (HP:0100660)1.65379280
128Basal cell carcinoma (HP:0002671)1.65291979
129Ureteral stenosis (HP:0000071)1.65011248
130Multiple enchondromatosis (HP:0005701)1.64562249
131Recurrent lower respiratory tract infections (HP:0002783)1.64525174
132Gangrene (HP:0100758)1.64507565

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K126.93874477
2MAP4K16.27616693
3TESK25.45595720
4TXK4.57395262
5ZAP704.34464363
6KDR3.82901536
7PRPF4B3.09251426
8RIPK42.87672195
9TESK12.82022040
10MAP3K112.72782992
11MYLK2.62732662
12LIMK12.37300057
13DAPK11.98386280
14EIF2AK11.96301154
15EPHB11.91636085
16SCYL21.90909327
17LCK1.69512530
18NLK1.66740323
19IKBKE1.64807491
20SYK1.59132934
21ITK1.58048106
22CSK1.57176906
23TRIB31.46989976
24MAP3K101.44217912
25JAK11.34995682
26FGFR11.31209666
27STK241.24375601
28FGFR41.23331931
29SMG11.21612077
30TAOK11.20840248
31TEC1.18870619
32BLK1.15952912
33TYK21.12535031
34MARK31.11845866
35TBK11.08699868
36MAP3K31.08443836
37MAP3K61.08387958
38SIK31.05423599
39PASK1.05154001
40PTK21.05126897
41GRK61.03590912
42EPHA31.01015841
43TLK11.00027842
44CAMKK10.99373986
45DAPK30.95456482
46LYN0.94733140
47JAK30.93806687
48EIF2AK30.92875443
49PAK40.89187541
50KIT0.89068582
51CDK120.88330384
52CAMKK20.86605762
53HIPK20.86265643
54PDK10.85785398
55MAP3K70.85719926
56CDK40.82797690
57TGFBR20.81508844
58BTK0.79806860
59PDGFRB0.79690125
60ILK0.78848825
61PTK60.76242842
62MAPK120.75967245
63MAP2K20.75138335
64TAOK20.74687529
65FYN0.73220789
66HCK0.72551678
67SIK20.71069778
68SIK10.70460831
69MAP3K140.70062242
70MAP3K130.67365291
71IRAK10.62987529
72KSR20.59799366
73MAP2K60.58443368
74GRK70.57374390
75DYRK1B0.57040028
76MAPK70.56613177
77CSF1R0.55736766
78INSR0.52808660
79IRAK40.48607705
80PRKCD0.48104409
81DAPK20.47363419
82PRKCH0.47178444
83RET0.47137880
84PDPK10.43400300
85ERN10.41134912
86ROCK10.40705601
87NME20.38569323
88RPS6KC10.37696132
89RPS6KL10.37696132
90PRKCQ0.36734784
91MAPKAPK20.35655006
92LRRK20.34866057
93IRAK30.34861940
94STK100.32845555
95RPS6KA60.32820707
96MAPKAPK30.32605524
97CHUK0.31016632
98YES10.30839934
99MAPK110.30425538
100SRC0.29980391
101MOS0.29913890
102BRD40.29842897
103BRSK10.29817587
104FGR0.28817444
105STK110.28676011
106IGF1R0.28472833
107IKBKB0.27274205
108PKN20.27085981
109DDR20.25867186
110MAP2K30.25692614
111ICK0.24923905
112SGK30.24817067
113MARK20.24329320
114MAP3K10.24236497
115ROCK20.23027567
116MAPK150.22839747
117ERBB40.22529796
118ABL10.19601240
119FGFR30.18653523
120MST40.17656198
121PRKD20.17129586
122TNK20.15643296
123FES0.15031971
124MATK0.13821110
125JAK20.12958523
126PRKD10.12644871
127CDC42BPA0.10361745
128UHMK10.10348595
129MAPK30.08497964
130TYRO30.08375030
131CSNK1G30.05455769
132DYRK20.04819795
133TAOK30.04443662
134CSNK1A10.04379908
135PIM10.03934728
136CLK10.03896981
137MAP3K80.03436934
138MAP2K40.03310315
139MAPK40.03024703
140FLT30.01587952
141CSNK2A10.01066114

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053407.58301995
2Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046504.74561970
3Graft-versus-host disease_Homo sapiens_hsa053323.90369011
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.84317126
5T cell receptor signaling pathway_Homo sapiens_hsa046603.79790207
6Antigen processing and presentation_Homo sapiens_hsa046122.81160567
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.59719347
8Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.53757220
9Measles_Homo sapiens_hsa051622.37779693
10NF-kappa B signaling pathway_Homo sapiens_hsa040642.37189162
11* Hematopoietic cell lineage_Homo sapiens_hsa046402.31918899
12Allograft rejection_Homo sapiens_hsa053302.16974793
13Viral myocarditis_Homo sapiens_hsa054162.01325417
14Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.75718624
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.57561737
16Staphylococcus aureus infection_Homo sapiens_hsa051501.56095242
17Leishmaniasis_Homo sapiens_hsa051401.52398165
18Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.48304152
19Osteoclast differentiation_Homo sapiens_hsa043801.37881219
20Chemokine signaling pathway_Homo sapiens_hsa040621.37379427
21VEGF signaling pathway_Homo sapiens_hsa043701.34709484
22Non-small cell lung cancer_Homo sapiens_hsa052231.34368923
23Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.33985050
24Protein export_Homo sapiens_hsa030601.33227919
25Leukocyte transendothelial migration_Homo sapiens_hsa046701.28590423
26Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.21023443
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.20998183
28Shigellosis_Homo sapiens_hsa051311.20667218
29B cell receptor signaling pathway_Homo sapiens_hsa046621.16573643
30RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.15455511
31Autoimmune thyroid disease_Homo sapiens_hsa053201.15149055
32Homologous recombination_Homo sapiens_hsa034401.14196043
33Jak-STAT signaling pathway_Homo sapiens_hsa046301.13120906
34Circadian rhythm_Homo sapiens_hsa047101.10107350
35Chronic myeloid leukemia_Homo sapiens_hsa052201.05702084
36Malaria_Homo sapiens_hsa051440.99492891
37Hepatitis C_Homo sapiens_hsa051600.94825108
38Regulation of actin cytoskeleton_Homo sapiens_hsa048100.92617629
39African trypanosomiasis_Homo sapiens_hsa051430.92473899
40Asthma_Homo sapiens_hsa053100.91667688
41Proteasome_Homo sapiens_hsa030500.91242034
42Prolactin signaling pathway_Homo sapiens_hsa049170.80097243
43Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79766240
44Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79093329
45Endocytosis_Homo sapiens_hsa041440.77177138
46RNA degradation_Homo sapiens_hsa030180.73257725
47Apoptosis_Homo sapiens_hsa042100.72305852
48Rap1 signaling pathway_Homo sapiens_hsa040150.70958696
49Other glycan degradation_Homo sapiens_hsa005110.70504385
50Toxoplasmosis_Homo sapiens_hsa051450.70236705
51Base excision repair_Homo sapiens_hsa034100.70164936
52Herpes simplex infection_Homo sapiens_hsa051680.69421984
53Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68130228
54DNA replication_Homo sapiens_hsa030300.66651941
55Notch signaling pathway_Homo sapiens_hsa043300.65979694
56Choline metabolism in cancer_Homo sapiens_hsa052310.65385505
57Neurotrophin signaling pathway_Homo sapiens_hsa047220.65206115
58Fatty acid elongation_Homo sapiens_hsa000620.65184456
59HTLV-I infection_Homo sapiens_hsa051660.64699762
60p53 signaling pathway_Homo sapiens_hsa041150.64227029
61AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64042799
62Endometrial cancer_Homo sapiens_hsa052130.63486265
63Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63094704
64Platelet activation_Homo sapiens_hsa046110.62994036
65Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61773084
66Lysosome_Homo sapiens_hsa041420.60904534
67FoxO signaling pathway_Homo sapiens_hsa040680.60870478
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.60363420
69Spliceosome_Homo sapiens_hsa030400.59434164
70Phagosome_Homo sapiens_hsa041450.58559417
71Mismatch repair_Homo sapiens_hsa034300.57822034
72Salmonella infection_Homo sapiens_hsa051320.57147214
73Ribosome_Homo sapiens_hsa030100.56665321
74Inositol phosphate metabolism_Homo sapiens_hsa005620.56319548
75Renal cell carcinoma_Homo sapiens_hsa052110.55736247
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55268896
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.54658669
78Dorso-ventral axis formation_Homo sapiens_hsa043200.53038275
79Sulfur relay system_Homo sapiens_hsa041220.51906600
80Legionellosis_Homo sapiens_hsa051340.51894590
81MAPK signaling pathway_Homo sapiens_hsa040100.51672251
82Fatty acid biosynthesis_Homo sapiens_hsa000610.50496800
83Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.48893102
84Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46138431
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.45043538
86mTOR signaling pathway_Homo sapiens_hsa041500.44492000
87Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43773517
88Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43027582
89Prostate cancer_Homo sapiens_hsa052150.42679617
90Fanconi anemia pathway_Homo sapiens_hsa034600.40676117
91Tuberculosis_Homo sapiens_hsa051520.39341972
92Hepatitis B_Homo sapiens_hsa051610.38065315
93Ras signaling pathway_Homo sapiens_hsa040140.36829093
94Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36539777
95Primary bile acid biosynthesis_Homo sapiens_hsa001200.35414843
96Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.35389989
97Pentose phosphate pathway_Homo sapiens_hsa000300.35311349
98Pertussis_Homo sapiens_hsa051330.34167272
99Prion diseases_Homo sapiens_hsa050200.33945979
100Thyroid cancer_Homo sapiens_hsa052160.33386999
101Acute myeloid leukemia_Homo sapiens_hsa052210.32384218
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.32294227
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.32030186
104alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31883472
105GnRH signaling pathway_Homo sapiens_hsa049120.30741177
106RNA polymerase_Homo sapiens_hsa030200.30193741
107NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30142361
108Fatty acid degradation_Homo sapiens_hsa000710.28872305
109Regulation of autophagy_Homo sapiens_hsa041400.28642189
110ErbB signaling pathway_Homo sapiens_hsa040120.28637384
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.28516194
112Viral carcinogenesis_Homo sapiens_hsa052030.28327068
113HIF-1 signaling pathway_Homo sapiens_hsa040660.28251299
114Fatty acid metabolism_Homo sapiens_hsa012120.27671359
115Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27542300
116Epstein-Barr virus infection_Homo sapiens_hsa051690.27281913
117Type I diabetes mellitus_Homo sapiens_hsa049400.26981278
118ABC transporters_Homo sapiens_hsa020100.24894287
119Rheumatoid arthritis_Homo sapiens_hsa053230.23755076
120Glycerolipid metabolism_Homo sapiens_hsa005610.22993804
121Type II diabetes mellitus_Homo sapiens_hsa049300.22315837
122Focal adhesion_Homo sapiens_hsa045100.18540397
123TNF signaling pathway_Homo sapiens_hsa046680.17017265
124Influenza A_Homo sapiens_hsa051640.15030376
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.13624588
126Peroxisome_Homo sapiens_hsa041460.12751565
127Pancreatic cancer_Homo sapiens_hsa052120.12712383
128Insulin resistance_Homo sapiens_hsa049310.11303114
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.10278372
130Colorectal cancer_Homo sapiens_hsa052100.09730090
131Steroid biosynthesis_Homo sapiens_hsa001000.09439163
132Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.07743833
133SNARE interactions in vesicular transport_Homo sapiens_hsa041300.07066573
134Nitrogen metabolism_Homo sapiens_hsa009100.06889280
135Adipocytokine signaling pathway_Homo sapiens_hsa049200.06485711
136Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.04525496
137PPAR signaling pathway_Homo sapiens_hsa033200.04117493

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