Rank | Gene Set | Z-score |
---|---|---|
1 | * B cell receptor signaling pathway (GO:0050853) | 8.81646694 |
2 | antigen processing and presentation of endogenous antigen (GO:0019883) | 7.04033929 |
3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.98771143 |
4 | positive regulation of B cell differentiation (GO:0045579) | 6.53672639 |
5 | regulation of B cell differentiation (GO:0045577) | 6.20214819 |
6 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.96211690 |
7 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 5.48972399 |
8 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.33115580 |
9 | cellular response to zinc ion (GO:0071294) | 5.32014523 |
10 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.01561582 |
11 | negative regulation of cell killing (GO:0031342) | 5.01561582 |
12 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.00917715 |
13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.00917715 |
14 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.96808079 |
15 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.96808079 |
16 | modulation by symbiont of host immune response (GO:0052553) | 4.96808079 |
17 | positive regulation by symbiont of host defense response (GO:0052509) | 4.96808079 |
18 | modulation by symbiont of host defense response (GO:0052031) | 4.96808079 |
19 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.96808079 |
20 | B cell mediated immunity (GO:0019724) | 4.87376405 |
21 | regulation of gamma-delta T cell activation (GO:0046643) | 4.86819324 |
22 | detection of bacterium (GO:0016045) | 4.81080603 |
23 | negative regulation of histone methylation (GO:0031061) | 4.60250471 |
24 | regulation of antigen processing and presentation (GO:0002577) | 4.57864196 |
25 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.55361805 |
26 | detection of other organism (GO:0098543) | 4.47780476 |
27 | mature B cell differentiation (GO:0002335) | 4.40006218 |
28 | cytidine deamination (GO:0009972) | 4.37567973 |
29 | cytidine metabolic process (GO:0046087) | 4.37567973 |
30 | cytidine catabolic process (GO:0006216) | 4.37567973 |
31 | regulation of B cell proliferation (GO:0030888) | 4.37308367 |
32 | negative regulation of B cell proliferation (GO:0030889) | 4.32342966 |
33 | type I interferon signaling pathway (GO:0060337) | 4.28990969 |
34 | cellular response to type I interferon (GO:0071357) | 4.28990969 |
35 | positive thymic T cell selection (GO:0045059) | 4.28158000 |
36 | regulation of histone H3-K9 methylation (GO:0051570) | 4.27685746 |
37 | response to type I interferon (GO:0034340) | 4.26238658 |
38 | serine transport (GO:0032329) | 4.19297951 |
39 | regulation of superoxide anion generation (GO:0032928) | 4.11443187 |
40 | negative regulation of phagocytosis (GO:0050765) | 4.05472649 |
41 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.04380276 |
42 | regulation of B cell apoptotic process (GO:0002902) | 4.02432959 |
43 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.02151255 |
44 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235 | 4.01308948 |
45 | * antigen receptor-mediated signaling pathway (GO:0050851) | 3.93817901 |
46 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.91809323 |
47 | L-serine transport (GO:0015825) | 3.85565760 |
48 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.83742190 |
49 | B cell homeostasis (GO:0001782) | 3.83065447 |
50 | positive regulation of interferon-alpha production (GO:0032727) | 3.82024832 |
51 | lymphocyte homeostasis (GO:0002260) | 3.79718645 |
52 | T cell migration (GO:0072678) | 3.75164507 |
53 | * B cell proliferation (GO:0042100) | 3.71640052 |
54 | positive regulation of Rap GTPase activity (GO:0032854) | 3.70563999 |
55 | positive regulation of histone deacetylation (GO:0031065) | 3.68841762 |
56 | T cell homeostasis (GO:0043029) | 3.67140862 |
57 | positive regulation of antigen processing and presentation (GO:0002579) | 3.67085599 |
58 | V(D)J recombination (GO:0033151) | 3.65269654 |
59 | * immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.63945854 |
60 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.61929475 |
61 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.60818046 |
62 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.58499265 |
63 | lymphocyte costimulation (GO:0031294) | 3.58104055 |
64 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.57810291 |
65 | regulation of interferon-alpha production (GO:0032647) | 3.55807230 |
66 | natural killer cell differentiation (GO:0001779) | 3.55505402 |
67 | positive regulation of immunoglobulin production (GO:0002639) | 3.53570157 |
68 | defense response to protozoan (GO:0042832) | 3.52172414 |
69 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:0002 | 3.51906686 |
70 | Fc-gamma receptor signaling pathway (GO:0038094) | 3.51906686 |
71 | Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096) | 3.51906686 |
72 | * B cell activation (GO:0042113) | 3.51022925 |
73 | positive regulation of gene expression, epigenetic (GO:0045815) | 3.48591835 |
74 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.48557526 |
75 | negative regulation of bone resorption (GO:0045779) | 3.48000378 |
76 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.46158363 |
77 | Fc receptor mediated stimulatory signaling pathway (GO:0002431) | 3.45760622 |
78 | positive regulation of B cell activation (GO:0050871) | 3.44467539 |
79 | response to interleukin-15 (GO:0070672) | 3.43902712 |
80 | positive regulation of B cell proliferation (GO:0030890) | 3.43565424 |
81 | lymph node development (GO:0048535) | 3.41573321 |
82 | negative regulation of B cell apoptotic process (GO:0002903) | 3.40604710 |
83 | T-helper 1 type immune response (GO:0042088) | 3.39671930 |
84 | immunoglobulin mediated immune response (GO:0016064) | 3.36657393 |
85 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.36583248 |
86 | response to host immune response (GO:0052572) | 3.36583248 |
87 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.35143398 |
88 | regulation of B cell activation (GO:0050864) | 3.35061361 |
89 | cellular response to interleukin-15 (GO:0071350) | 3.33200297 |
90 | mature B cell differentiation involved in immune response (GO:0002313) | 3.32679371 |
91 | positive regulation of type 2 immune response (GO:0002830) | 3.32579940 |
92 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.31867787 |
93 | cellular response to interferon-gamma (GO:0071346) | 3.31202000 |
94 | leukocyte homeostasis (GO:0001776) | 3.30122069 |
95 | T cell selection (GO:0045058) | 3.26749055 |
96 | leukocyte aggregation (GO:0070486) | 3.24175529 |
97 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.23838557 |
98 | vesicle targeting (GO:0006903) | 3.23185240 |
99 | regulation of germinal center formation (GO:0002634) | 3.22857771 |
100 | germinal center formation (GO:0002467) | 3.18261540 |
101 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.17629876 |
102 | detection of external biotic stimulus (GO:0098581) | 3.17231328 |
103 | positive regulation of humoral immune response (GO:0002922) | 3.15580958 |
104 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.13424695 |
105 | thymic T cell selection (GO:0045061) | 3.12812706 |
106 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 3.11894323 |
107 | respiratory burst (GO:0045730) | 3.11887702 |
108 | tachykinin receptor signaling pathway (GO:0007217) | 3.11201069 |
109 | response to host (GO:0075136) | 3.11033414 |
110 | response to host defenses (GO:0052200) | 3.11033414 |
111 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.11033414 |
112 | neutrophil activation (GO:0042119) | 3.09826804 |
113 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.08278743 |
114 | myeloid dendritic cell activation (GO:0001773) | 3.07329592 |
115 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.05237346 |
116 | Peyers patch development (GO:0048541) | 3.05237346 |
117 | negative thymic T cell selection (GO:0045060) | 3.03956012 |
118 | T cell lineage commitment (GO:0002360) | 3.03681094 |
119 | regulation of Rap GTPase activity (GO:0032317) | 3.02135356 |
120 | positive regulation of macrophage cytokine production (GO:0060907) | 2.99252330 |
121 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.98949659 |
122 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.98949659 |
123 | response to protozoan (GO:0001562) | 2.98505817 |
124 | positive regulation of cell adhesion mediated by integrin (GO:0033630) | 2.98476999 |
125 | positive regulation of protein deacetylation (GO:0090312) | 2.97523768 |
126 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.96777382 |
127 | negative regulation of gene silencing (GO:0060969) | 2.95391384 |
128 | positive regulation of granulocyte differentiation (GO:0030854) | 2.95246909 |
129 | myeloid dendritic cell differentiation (GO:0043011) | 2.95141365 |
130 | viral transcription (GO:0019083) | 2.95010538 |
131 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.94624350 |
132 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.92875782 |
133 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.92684899 |
134 | macrophage activation involved in immune response (GO:0002281) | 2.92437558 |
135 | ribosomal small subunit assembly (GO:0000028) | 2.90720916 |
136 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.90356666 |
137 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.88882500 |
138 | tolerance induction (GO:0002507) | 2.88735673 |
139 | positive regulation of interleukin-2 production (GO:0032743) | 2.87769256 |
140 | hepatocyte apoptotic process (GO:0097284) | 2.87612781 |
141 | humoral immune response (GO:0006959) | 2.86941341 |
142 | positive T cell selection (GO:0043368) | 2.86631880 |
143 | * B cell differentiation (GO:0030183) | 2.86472438 |
144 | NIK/NF-kappaB signaling (GO:0038061) | 2.86056616 |
145 | complement activation, classical pathway (GO:0006958) | 2.85990583 |
146 | positive regulation of lamellipodium assembly (GO:0010592) | 2.85036782 |
147 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.82353803 |
148 | activation of JUN kinase activity (GO:0007257) | 2.76098104 |
149 | T cell costimulation (GO:0031295) | 2.75998384 |
150 | adaptation of signaling pathway (GO:0023058) | 2.74458270 |
151 | negative T cell selection (GO:0043383) | 2.73962501 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.92775901 |
2 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.74214343 |
3 | MYC_22102868_ChIP-Seq_BL_Human | 5.43282380 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.14510637 |
5 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.96059070 |
6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.77812335 |
7 | * VDR_21846776_ChIP-Seq_THP-1_Human | 3.54156597 |
8 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.23895548 |
9 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.23081874 |
10 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 3.09407076 |
11 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.07800012 |
12 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.01078244 |
13 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.86610833 |
14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.86246430 |
15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.52437161 |
16 | * MAF_26560356_Chip-Seq_TH1_Human | 2.47592187 |
17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.46637778 |
18 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.46319935 |
19 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.39875036 |
20 | * MYB_26560356_Chip-Seq_TH1_Human | 2.39613941 |
21 | * MYB_26560356_Chip-Seq_TH2_Human | 2.39345103 |
22 | * UTX_26944678_Chip-Seq_JUKART_Human | 2.38818370 |
23 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.27336527 |
24 | * VDR_24763502_ChIP-Seq_THP-1_Human | 2.24563052 |
25 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.16474781 |
26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.15913756 |
27 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.14376025 |
28 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.06617275 |
29 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.98217808 |
30 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.96389236 |
31 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.92740844 |
32 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.91057690 |
33 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.83569591 |
34 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.80718344 |
35 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.74786778 |
36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.70764713 |
37 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.66917668 |
38 | MAF_26560356_Chip-Seq_TH2_Human | 1.66635223 |
39 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.66513776 |
40 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.65749102 |
41 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65467147 |
42 | SPI1_23127762_ChIP-Seq_K562_Human | 1.63746975 |
43 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.62105969 |
44 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.61506667 |
45 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.60959254 |
46 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.58777073 |
47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55159252 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50784728 |
49 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.48211733 |
50 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47291898 |
51 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.45728470 |
52 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.45701199 |
53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.42626135 |
54 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.41750181 |
55 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.41585321 |
56 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.40929572 |
57 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.38195960 |
58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.37280232 |
59 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.36516962 |
60 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.35768610 |
61 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.34443117 |
62 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.25643368 |
63 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.24896789 |
64 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.24842938 |
65 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.21299293 |
66 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.20355132 |
67 | GATA1_22025678_ChIP-Seq_K562_Human | 1.19986683 |
68 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.18043423 |
69 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.15331950 |
70 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.13124126 |
71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.11145898 |
72 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.08898067 |
73 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.08125642 |
74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08083404 |
75 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.06551004 |
76 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.05180216 |
77 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.02111814 |
78 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.01846354 |
79 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.01551122 |
80 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01203871 |
81 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.99996207 |
82 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.99175150 |
83 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.97892469 |
84 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.95280826 |
85 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.94410325 |
86 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.94219210 |
87 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93290495 |
88 | P300_27268052_Chip-Seq_Bcells_Human | 0.92471326 |
89 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.91641592 |
90 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.90936086 |
91 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.89183412 |
92 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.87759478 |
93 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.85663165 |
94 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.85423966 |
95 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.85185177 |
96 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.85120253 |
97 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84937891 |
98 | P68_20966046_ChIP-Seq_HELA_Human | 0.84930914 |
99 | * LXR_22292898_ChIP-Seq_THP-1_Human | 0.84880089 |
100 | GATA3_26560356_Chip-Seq_TH2_Human | 0.84537355 |
101 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84528948 |
102 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.84017031 |
103 | * SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.81896087 |
104 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.80242618 |
105 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.80121710 |
106 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.79771747 |
107 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78865872 |
108 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.78146938 |
109 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.77562071 |
110 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.76015090 |
111 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.73918418 |
112 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.73085507 |
113 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.72861534 |
114 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.71628159 |
115 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.71270430 |
116 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.71019448 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 5.38656797 |
2 | * MP0001800_abnormal_humoral_immune | 5.06766383 |
3 | * MP0001790_abnormal_immune_system | 4.60096614 |
4 | * MP0005387_immune_system_phenotype | 4.60096614 |
5 | MP0000685_abnormal_immune_system | 3.94237839 |
6 | * MP0002452_abnormal_antigen_presenting | 3.79440972 |
7 | MP0003303_peritoneal_inflammation | 3.57058135 |
8 | MP0005000_abnormal_immune_tolerance | 3.15183236 |
9 | * MP0002723_abnormal_immune_serum | 3.11909962 |
10 | * MP0002398_abnormal_bone_marrow | 3.11755898 |
11 | * MP0002420_abnormal_adaptive_immunity | 3.09876365 |
12 | * MP0001819_abnormal_immune_cell | 3.00234921 |
13 | MP0005671_abnormal_response_to | 2.93711171 |
14 | * MP0000716_abnormal_immune_system | 2.79541043 |
15 | * MP0000689_abnormal_spleen_morphology | 2.78883820 |
16 | MP0002722_abnormal_immune_system | 2.42056515 |
17 | MP0003763_abnormal_thymus_physiology | 2.31408817 |
18 | * MP0002429_abnormal_blood_cell | 2.30683428 |
19 | MP0002396_abnormal_hematopoietic_system | 2.26396154 |
20 | MP0003300_gastrointestinal_ulcer | 2.11338329 |
21 | MP0005025_abnormal_response_to | 2.02571524 |
22 | MP0004808_abnormal_hematopoietic_stem | 2.01580945 |
23 | MP0003724_increased_susceptibility_to | 1.99537749 |
24 | MP0002166_altered_tumor_susceptibility | 1.94410823 |
25 | MP0009785_altered_susceptibility_to | 1.92027287 |
26 | MP0000703_abnormal_thymus_morphology | 1.88729301 |
27 | MP0003436_decreased_susceptibility_to | 1.87440132 |
28 | MP0001873_stomach_inflammation | 1.80057526 |
29 | MP0002419_abnormal_innate_immunity | 1.75872474 |
30 | MP0002148_abnormal_hypersensitivity_rea | 1.71272368 |
31 | MP0002405_respiratory_system_inflammati | 1.70516510 |
32 | MP0008057_abnormal_DNA_replication | 1.69161854 |
33 | MP0010155_abnormal_intestine_physiology | 1.67818289 |
34 | MP0006054_spinal_hemorrhage | 1.62929168 |
35 | MP0001845_abnormal_inflammatory_respons | 1.61156148 |
36 | MP0010094_abnormal_chromosome_stability | 1.60688232 |
37 | MP0004947_skin_inflammation | 1.60339707 |
38 | MP0005645_abnormal_hypothalamus_physiol | 1.50948807 |
39 | MP0001879_abnormal_lymphatic_vessel | 1.45401393 |
40 | MP0002019_abnormal_tumor_incidence | 1.39394198 |
41 | MP0001853_heart_inflammation | 1.38686027 |
42 | MP0004510_myositis | 1.37651108 |
43 | MP0002933_joint_inflammation | 1.36189432 |
44 | MP0003866_abnormal_defecation | 1.34343554 |
45 | MP0009278_abnormal_bone_marrow | 1.33306937 |
46 | MP0005464_abnormal_platelet_physiology | 1.32501811 |
47 | MP0009333_abnormal_splenocyte_physiolog | 1.30761280 |
48 | MP0001348_abnormal_lacrimal_gland | 1.28350342 |
49 | MP0010234_abnormal_vibrissa_follicle | 1.24672079 |
50 | MP0002006_tumorigenesis | 1.23007359 |
51 | MP0005310_abnormal_salivary_gland | 1.22817749 |
52 | * MP0003077_abnormal_cell_cycle | 1.13851871 |
53 | MP0000465_gastrointestinal_hemorrhage | 1.13198138 |
54 | MP0010352_gastrointestinal_tract_polyps | 1.11326334 |
55 | MP0003183_abnormal_peptide_metabolism | 1.11160559 |
56 | MP0003693_abnormal_embryo_hatching | 1.09133367 |
57 | MP0000490_abnormal_crypts_of | 1.05197739 |
58 | MP0003172_abnormal_lysosome_physiology | 1.03873976 |
59 | MP0005075_abnormal_melanosome_morpholog | 1.03057467 |
60 | MP0003111_abnormal_nucleus_morphology | 1.01295700 |
61 | MP0002009_preneoplasia | 0.99202062 |
62 | MP0008961_abnormal_basal_metabolism | 0.97470422 |
63 | MP0002136_abnormal_kidney_physiology | 0.95804939 |
64 | MP0005076_abnormal_cell_differentiation | 0.94643265 |
65 | MP0008260_abnormal_autophagy | 0.91593017 |
66 | MP0004381_abnormal_hair_follicle | 0.90047706 |
67 | MP0005397_hematopoietic_system_phenotyp | 0.88673924 |
68 | MP0001545_abnormal_hematopoietic_system | 0.88673924 |
69 | MP0000350_abnormal_cell_proliferation | 0.88241961 |
70 | MP0002132_abnormal_respiratory_system | 0.85957232 |
71 | MP0003091_abnormal_cell_migration | 0.85392769 |
72 | MP0004957_abnormal_blastocyst_morpholog | 0.85136561 |
73 | MP0008469_abnormal_protein_level | 0.80339719 |
74 | MP0000858_altered_metastatic_potential | 0.77490463 |
75 | MP0003045_fibrosis | 0.76579515 |
76 | MP0003787_abnormal_imprinting | 0.74550012 |
77 | MP0008874_decreased_physiological_sensi | 0.73695363 |
78 | MP0002928_abnormal_bile_duct | 0.73068110 |
79 | MP0003252_abnormal_bile_duct | 0.72090272 |
80 | MP0002095_abnormal_skin_pigmentation | 0.71474558 |
81 | MP0001730_embryonic_growth_arrest | 0.70264862 |
82 | MP0002138_abnormal_hepatobiliary_system | 0.70031730 |
83 | MP0000313_abnormal_cell_death | 0.69436790 |
84 | MP0003566_abnormal_cell_adhesion | 0.65567643 |
85 | MP0010307_abnormal_tumor_latency | 0.64971132 |
86 | MP0009764_decreased_sensitivity_to | 0.64889510 |
87 | MP0002139_abnormal_hepatobiliary_system | 0.64870909 |
88 | MP0005174_abnormal_tail_pigmentation | 0.64359693 |
89 | MP0001663_abnormal_digestive_system | 0.62798920 |
90 | MP0008058_abnormal_DNA_repair | 0.62458681 |
91 | MP0009763_increased_sensitivity_to | 0.59864255 |
92 | MP0001533_abnormal_skeleton_physiology | 0.58777757 |
93 | MP0002909_abnormal_adrenal_gland | 0.58285533 |
94 | MP0001851_eye_inflammation | 0.56279357 |
95 | MP0002083_premature_death | 0.54893022 |
96 | MP0003646_muscle_fatigue | 0.53562618 |
97 | * MP0005621_abnormal_cell_physiology | 0.52731201 |
98 | MP0000013_abnormal_adipose_tissue | 0.52692073 |
99 | MP0005381_digestive/alimentary_phenotyp | 0.51692070 |
100 | MP0009931_abnormal_skin_appearance | 0.50386869 |
101 | MP0000477_abnormal_intestine_morphology | 0.49292083 |
102 | MP0000249_abnormal_blood_vessel | 0.49218118 |
103 | MP0002998_abnormal_bone_remodeling | 0.48997581 |
104 | MP0000609_abnormal_liver_physiology | 0.48639021 |
105 | MP0002693_abnormal_pancreas_physiology | 0.48169763 |
106 | MP0000003_abnormal_adipose_tissue | 0.46950702 |
107 | MP0004883_abnormal_blood_vessel | 0.46886698 |
108 | MP0003943_abnormal_hepatobiliary_system | 0.46493797 |
109 | MP0003191_abnormal_cellular_cholesterol | 0.45923146 |
110 | MP0005166_decreased_susceptibility_to | 0.45722552 |
111 | MP0006082_CNS_inflammation | 0.45512388 |
112 | MP0001784_abnormal_fluid_regulation | 0.45507475 |
113 | MP0003453_abnormal_keratinocyte_physiol | 0.43463427 |
114 | MP0005451_abnormal_body_composition | 0.42820796 |
115 | MP0000767_abnormal_smooth_muscle | 0.41879762 |
116 | MP0000015_abnormal_ear_pigmentation | 0.41830395 |
117 | MP0000598_abnormal_liver_morphology | 0.40657483 |
118 | MP0002163_abnormal_gland_morphology | 0.40144645 |
119 | MP0002080_prenatal_lethality | 0.39629334 |
120 | MP0001986_abnormal_taste_sensitivity | 0.39046911 |
121 | MP0000371_diluted_coat_color | 0.38503008 |
122 | MP0009642_abnormal_blood_homeostasis | 0.36734107 |
123 | MP0003075_altered_response_to | 0.35972187 |
124 | MP0009643_abnormal_urine_homeostasis | 0.35741410 |
125 | MP0009765_abnormal_xenobiotic_induced | 0.34774850 |
126 | MP0002254_reproductive_system_inflammat | 0.33523544 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Agammaglobulinemia (HP:0004432) | 9.63826869 |
2 | Gastrointestinal stroma tumor (HP:0100723) | 7.02447540 |
3 | * Cellulitis (HP:0100658) | 6.80796117 |
4 | Recurrent sinusitis (HP:0011108) | 6.30740151 |
5 | * Papilloma (HP:0012740) | 6.14596972 |
6 | * Verrucae (HP:0200043) | 6.14596972 |
7 | Colitis (HP:0002583) | 6.06736753 |
8 | B lymphocytopenia (HP:0010976) | 5.33084452 |
9 | Abnormality of B cell number (HP:0010975) | 5.33084452 |
10 | Recurrent viral infections (HP:0004429) | 5.25057023 |
11 | IgM deficiency (HP:0002850) | 5.20364816 |
12 | Panhypogammaglobulinemia (HP:0003139) | 5.17501899 |
13 | Chronic sinusitis (HP:0011109) | 5.17496274 |
14 | Inflammation of the large intestine (HP:0002037) | 5.15669341 |
15 | Gastrointestinal inflammation (HP:0004386) | 5.08327939 |
16 | Small epiphyses (HP:0010585) | 4.95096795 |
17 | * Recurrent bronchitis (HP:0002837) | 4.92307170 |
18 | * Meningitis (HP:0001287) | 4.64970801 |
19 | Recurrent pneumonia (HP:0006532) | 4.63503561 |
20 | Lymphopenia (HP:0001888) | 4.60158491 |
21 | Thyroiditis (HP:0100646) | 4.46468834 |
22 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 4.43238621 |
23 | Recurrent lower respiratory tract infections (HP:0002783) | 4.36757880 |
24 | Emphysema (HP:0002097) | 4.26475787 |
25 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.20138250 |
26 | * Osteomyelitis (HP:0002754) | 3.85689702 |
27 | Abnormality of macrophages (HP:0004311) | 3.82803317 |
28 | Chronic otitis media (HP:0000389) | 3.82777643 |
29 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.58509351 |
30 | Vertebral arch anomaly (HP:0008438) | 3.56729766 |
31 | Mitral stenosis (HP:0001718) | 3.55580912 |
32 | Vasculitis (HP:0002633) | 3.55055135 |
33 | IgA deficiency (HP:0002720) | 3.49327840 |
34 | * Sepsis (HP:0100806) | 3.48125168 |
35 | * Recurrent otitis media (HP:0000403) | 3.39609204 |
36 | Restrictive lung disease (HP:0002091) | 3.35835910 |
37 | Urticaria (HP:0001025) | 3.32052581 |
38 | Recurrent fungal infections (HP:0002841) | 3.31263296 |
39 | IgG deficiency (HP:0004315) | 3.27392409 |
40 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 3.24987123 |
41 | Flattened epiphyses (HP:0003071) | 3.19749031 |
42 | Abnormality of the fingertips (HP:0001211) | 2.92469520 |
43 | Abnormality of T cells (HP:0002843) | 2.89638972 |
44 | Abnormality of the prostate (HP:0008775) | 2.88259302 |
45 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.83520517 |
46 | Recurrent cutaneous fungal infections (HP:0011370) | 2.83520517 |
47 | Abnormality of T cell physiology (HP:0011840) | 2.82472756 |
48 | T lymphocytopenia (HP:0005403) | 2.81248824 |
49 | Abnormality of the intervertebral disk (HP:0005108) | 2.80319417 |
50 | Recurrent abscess formation (HP:0002722) | 2.80131317 |
51 | Autoimmune thrombocytopenia (HP:0001973) | 2.79801371 |
52 | Recurrent bacterial skin infections (HP:0005406) | 2.78669257 |
53 | Abnormality of T cell number (HP:0011839) | 2.75139673 |
54 | Lymphoma (HP:0002665) | 2.74362205 |
55 | * Bronchitis (HP:0012387) | 2.69682805 |
56 | Increased IgM level (HP:0003496) | 2.66232941 |
57 | Combined immunodeficiency (HP:0005387) | 2.65452392 |
58 | Gastrointestinal infarctions (HP:0005244) | 2.64430596 |
59 | Ulnar bowing (HP:0003031) | 2.62379202 |
60 | Irregular vertebral endplates (HP:0003301) | 2.61604140 |
61 | Viral hepatitis (HP:0006562) | 2.59988120 |
62 | Absent epiphyses (HP:0010577) | 2.58737818 |
63 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.58737818 |
64 | Chest pain (HP:0100749) | 2.58215158 |
65 | Retrobulbar optic neuritis (HP:0100654) | 2.53030771 |
66 | Optic neuritis (HP:0100653) | 2.53030771 |
67 | Leukopenia (HP:0001882) | 2.52182512 |
68 | Severe combined immunodeficiency (HP:0004430) | 2.50334656 |
69 | Mediastinal lymphadenopathy (HP:0100721) | 2.49580669 |
70 | Myositis (HP:0100614) | 2.49390985 |
71 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.46570065 |
72 | * Skin rash (HP:0000988) | 2.42798603 |
73 | Orchitis (HP:0100796) | 2.40064269 |
74 | Recurrent skin infections (HP:0001581) | 2.39924877 |
75 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.39886979 |
76 | Abnormality of the pleura (HP:0002103) | 2.32677937 |
77 | Arthropathy (HP:0003040) | 2.32430638 |
78 | Hypertensive crisis (HP:0100735) | 2.29810698 |
79 | Thrombocytosis (HP:0001894) | 2.28048623 |
80 | Interstitial pulmonary disease (HP:0006530) | 2.25259659 |
81 | Hypoplasia of the thymus (HP:0000778) | 2.23534233 |
82 | Gingivitis (HP:0000230) | 2.23331648 |
83 | Hypergammaglobulinemia (HP:0010702) | 2.17134983 |
84 | Premature loss of primary teeth (HP:0006323) | 2.11057187 |
85 | * Skin ulcer (HP:0200042) | 2.08774945 |
86 | Abnormality of the peritoneum (HP:0002585) | 2.07306974 |
87 | Encephalitis (HP:0002383) | 2.05617151 |
88 | Hemoptysis (HP:0002105) | 2.04589321 |
89 | Spontaneous hematomas (HP:0007420) | 2.03106466 |
90 | Eosinophilia (HP:0001880) | 2.02792680 |
91 | Basal cell carcinoma (HP:0002671) | 2.01415264 |
92 | Xerostomia (HP:0000217) | 1.99946808 |
93 | Increased IgE level (HP:0003212) | 1.99323064 |
94 | Nasal polyposis (HP:0100582) | 1.98281193 |
95 | Abnormality of male internal genitalia (HP:0000022) | 1.98154348 |
96 | Pustule (HP:0200039) | 1.97456085 |
97 | Pulmonary fibrosis (HP:0002206) | 1.95142036 |
98 | Abnormality of the vertebral endplates (HP:0005106) | 1.93897582 |
99 | Chronic diarrhea (HP:0002028) | 1.93713487 |
100 | Obstructive lung disease (HP:0006536) | 1.93422721 |
101 | Chronic obstructive pulmonary disease (HP:0006510) | 1.93422721 |
102 | Limited elbow extension (HP:0001377) | 1.92666149 |
103 | Prolonged bleeding time (HP:0003010) | 1.91930646 |
104 | Fatigue (HP:0012378) | 1.91222162 |
105 | Autoimmune hemolytic anemia (HP:0001890) | 1.90256895 |
106 | Petechiae (HP:0000967) | 1.90172193 |
107 | Keratoconjunctivitis sicca (HP:0001097) | 1.89983893 |
108 | Stomatitis (HP:0010280) | 1.89231830 |
109 | Barrel-shaped chest (HP:0001552) | 1.87808086 |
110 | Acrocyanosis (HP:0001063) | 1.86832035 |
111 | Epistaxis (HP:0000421) | 1.82966442 |
112 | Hypochromic anemia (HP:0001931) | 1.82824391 |
113 | * Neutropenia (HP:0001875) | 1.81179205 |
114 | Leukocytosis (HP:0001974) | 1.79839586 |
115 | Pulmonary embolism (HP:0002204) | 1.79237606 |
116 | Granulocytopenia (HP:0001913) | 1.78094734 |
117 | Vertebral clefting (HP:0008428) | 1.77559380 |
118 | Eczematoid dermatitis (HP:0000976) | 1.75841962 |
119 | Hematochezia (HP:0002573) | 1.73137702 |
120 | Arthralgia (HP:0002829) | 1.71652959 |
121 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.69047880 |
122 | Aortic regurgitation (HP:0001659) | 1.66803840 |
123 | Long eyelashes (HP:0000527) | 1.63639910 |
124 | Abnormality of eosinophils (HP:0001879) | 1.63165673 |
125 | Abnormality of the nasal mucosa (HP:0000433) | 1.63114935 |
126 | Papilledema (HP:0001085) | 1.61401398 |
127 | Cutaneous melanoma (HP:0012056) | 1.57945233 |
128 | Pulmonary infiltrates (HP:0002113) | 1.52284169 |
129 | Hepatitis (HP:0012115) | 1.51783179 |
130 | Villous atrophy (HP:0011473) | 1.51062761 |
131 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.51062761 |
132 | Abnormality of the thymus (HP:0000777) | 1.50541426 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 6.37031963 |
2 | MAP3K10 | 5.98006410 |
3 | ERN1 | 4.11833595 |
4 | GRK6 | 3.59110698 |
5 | EEF2K | 2.98113248 |
6 | PRPF4B | 2.89894571 |
7 | CSF1R | 2.81825038 |
8 | BLK | 2.76086339 |
9 | BTK | 2.51946995 |
10 | STK10 | 2.35099058 |
11 | SIK2 | 2.31733894 |
12 | RIPK4 | 2.30429246 |
13 | * SYK | 2.26366286 |
14 | LRRK2 | 2.17039404 |
15 | SMG1 | 2.12003567 |
16 | MAP3K13 | 1.73341162 |
17 | CDK12 | 1.63555135 |
18 | TYK2 | 1.51876169 |
19 | CLK1 | 1.38979443 |
20 | MAP3K14 | 1.37662105 |
21 | * LYN | 1.37026099 |
22 | NEK2 | 1.32240461 |
23 | BMPR2 | 1.29371856 |
24 | HCK | 1.28093928 |
25 | JAK1 | 1.27271589 |
26 | FES | 1.24592006 |
27 | EIF2AK3 | 1.23745730 |
28 | MST4 | 1.22291131 |
29 | VRK1 | 1.17002291 |
30 | TRIB3 | 1.16853610 |
31 | MARK3 | 1.13112092 |
32 | CDK4 | 1.09624095 |
33 | SIK3 | 1.09321810 |
34 | NEK9 | 1.09286222 |
35 | TBK1 | 1.05688672 |
36 | PIM1 | 1.03608581 |
37 | PRKCH | 1.03242384 |
38 | CSK | 1.01353672 |
39 | ITK | 1.00425821 |
40 | CDK19 | 0.99453483 |
41 | TNK2 | 0.97278631 |
42 | SIK1 | 0.94449368 |
43 | LCK | 0.91658981 |
44 | MAPK12 | 0.90737588 |
45 | IKBKB | 0.89996982 |
46 | PKN2 | 0.88364278 |
47 | ARAF | 0.87731212 |
48 | KIT | 0.87442967 |
49 | BRD4 | 0.87426698 |
50 | PRKD2 | 0.86763711 |
51 | MAP3K11 | 0.86458897 |
52 | ZAP70 | 0.85996122 |
53 | STK4 | 0.85732870 |
54 | PRKCQ | 0.85132668 |
55 | TEC | 0.84482369 |
56 | GRK1 | 0.82224042 |
57 | HIPK2 | 0.79560784 |
58 | IRAK3 | 0.76209108 |
59 | JAK3 | 0.75988043 |
60 | RPS6KB2 | 0.74941275 |
61 | JAK2 | 0.71918945 |
62 | RPS6KA4 | 0.70065466 |
63 | TESK2 | 0.69280454 |
64 | ALK | 0.68404570 |
65 | MAPK11 | 0.66638256 |
66 | DAPK3 | 0.66109502 |
67 | FGFR3 | 0.64856173 |
68 | IKBKE | 0.63341160 |
69 | MAP3K7 | 0.62583417 |
70 | TXK | 0.62042408 |
71 | MAPK4 | 0.61346642 |
72 | MAPK7 | 0.61304288 |
73 | MAP3K1 | 0.61116655 |
74 | KDR | 0.60505461 |
75 | MELK | 0.59775292 |
76 | TGFBR2 | 0.59237867 |
77 | DYRK1B | 0.58252880 |
78 | PRKD1 | 0.57239527 |
79 | IRAK4 | 0.56869487 |
80 | CDC42BPA | 0.56533429 |
81 | RPS6KA5 | 0.56256977 |
82 | NME2 | 0.56242797 |
83 | CHUK | 0.56176227 |
84 | CDK9 | 0.56165478 |
85 | ZAK | 0.55741997 |
86 | KSR2 | 0.55741316 |
87 | MATK | 0.54443619 |
88 | NLK | 0.51641173 |
89 | FRK | 0.49900548 |
90 | ABL1 | 0.49691857 |
91 | PDK1 | 0.49665424 |
92 | TAOK2 | 0.49601586 |
93 | MAP3K9 | 0.48593424 |
94 | TAOK1 | 0.48338429 |
95 | MAP3K8 | 0.47006632 |
96 | BRAF | 0.44466097 |
97 | PDPK1 | 0.44434666 |
98 | CDC7 | 0.44377522 |
99 | MAP2K2 | 0.44224527 |
100 | TAOK3 | 0.42728726 |
101 | SCYL2 | 0.42482140 |
102 | TLK1 | 0.39206484 |
103 | MARK2 | 0.38649068 |
104 | WNK1 | 0.36481745 |
105 | * FYN | 0.35594478 |
106 | CHEK1 | 0.34835607 |
107 | PASK | 0.34136034 |
108 | DYRK3 | 0.33689374 |
109 | ICK | 0.33650141 |
110 | TAF1 | 0.33236832 |
111 | STK24 | 0.33228498 |
112 | PTK6 | 0.33215613 |
113 | FGFR4 | 0.33120423 |
114 | FGFR2 | 0.33023620 |
115 | PRKCI | 0.31534464 |
116 | YES1 | 0.30686542 |
117 | FGR | 0.30569577 |
118 | CSNK1D | 0.29837760 |
119 | CDK6 | 0.29606427 |
120 | CCNB1 | 0.29442087 |
121 | MAP2K3 | 0.28545899 |
122 | MAPKAPK2 | 0.28146512 |
123 | ATR | 0.26004017 |
124 | SGK3 | 0.25261553 |
125 | MAP2K1 | 0.24847246 |
126 | EGFR | 0.23731607 |
127 | IRAK2 | 0.23591200 |
128 | PRKCD | 0.21266898 |
129 | MAPK3 | 0.21133074 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Primary immunodeficiency_Homo sapiens_hsa05340 | 6.42706728 |
2 | * B cell receptor signaling pathway_Homo sapiens_hsa04662 | 6.04787112 |
3 | Allograft rejection_Homo sapiens_hsa05330 | 4.59181751 |
4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.32386588 |
5 | Asthma_Homo sapiens_hsa05310 | 4.18739649 |
6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.11579161 |
7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.51350999 |
8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.83513743 |
9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.78016528 |
10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.61113229 |
11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.52406866 |
12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.41015271 |
13 | Base excision repair_Homo sapiens_hsa03410 | 2.33275678 |
14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.22768419 |
15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.09267160 |
16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.04143313 |
17 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.98797177 |
18 | Mismatch repair_Homo sapiens_hsa03430 | 1.85421985 |
19 | DNA replication_Homo sapiens_hsa03030 | 1.79618332 |
20 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.69762048 |
21 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.69673740 |
22 | Leishmaniasis_Homo sapiens_hsa05140 | 1.58728790 |
23 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.57647356 |
24 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.53328630 |
25 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.40405852 |
26 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.39967881 |
27 | Ribosome_Homo sapiens_hsa03010 | 1.39594711 |
28 | Measles_Homo sapiens_hsa05162 | 1.38730152 |
29 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.32828837 |
30 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.30916216 |
31 | Alcoholism_Homo sapiens_hsa05034 | 1.30476418 |
32 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.29429018 |
33 | Tuberculosis_Homo sapiens_hsa05152 | 1.22980503 |
34 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.21041478 |
35 | Shigellosis_Homo sapiens_hsa05131 | 1.13706403 |
36 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.13686577 |
37 | Platelet activation_Homo sapiens_hsa04611 | 1.12666363 |
38 | Hepatitis B_Homo sapiens_hsa05161 | 1.12597163 |
39 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.12171811 |
40 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.06878109 |
41 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.06449656 |
42 | Spliceosome_Homo sapiens_hsa03040 | 1.05311157 |
43 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99854981 |
44 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.99714319 |
45 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.99212839 |
46 | Apoptosis_Homo sapiens_hsa04210 | 0.98753902 |
47 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.96426268 |
48 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.94414104 |
49 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.93589683 |
50 | HTLV-I infection_Homo sapiens_hsa05166 | 0.93090075 |
51 | Homologous recombination_Homo sapiens_hsa03440 | 0.92527362 |
52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.91943303 |
53 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.91473218 |
54 | Phagosome_Homo sapiens_hsa04145 | 0.90725548 |
55 | Influenza A_Homo sapiens_hsa05164 | 0.89473097 |
56 | Glioma_Homo sapiens_hsa05214 | 0.83985624 |
57 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.77288363 |
58 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.74426662 |
59 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.73609362 |
60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.72852539 |
61 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.70760962 |
62 | Cell cycle_Homo sapiens_hsa04110 | 0.70187023 |
63 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.69095847 |
64 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.68820313 |
65 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.68774495 |
66 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68569519 |
67 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.67995543 |
68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.67934682 |
69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.67013650 |
70 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.62917885 |
71 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.62601247 |
72 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.62404929 |
73 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.61633049 |
74 | Colorectal cancer_Homo sapiens_hsa05210 | 0.59711616 |
75 | Lysine degradation_Homo sapiens_hsa00310 | 0.59088401 |
76 | Insulin resistance_Homo sapiens_hsa04931 | 0.59031655 |
77 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.57568574 |
78 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.57058994 |
79 | Prostate cancer_Homo sapiens_hsa05215 | 0.53558688 |
80 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.53337440 |
81 | Hepatitis C_Homo sapiens_hsa05160 | 0.51635116 |
82 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.48344793 |
83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.46200256 |
84 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.44399629 |
85 | Malaria_Homo sapiens_hsa05144 | 0.43559452 |
86 | Salmonella infection_Homo sapiens_hsa05132 | 0.42452031 |
87 | Endocytosis_Homo sapiens_hsa04144 | 0.42125046 |
88 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.40386619 |
89 | Other glycan degradation_Homo sapiens_hsa00511 | 0.39921488 |
90 | Pertussis_Homo sapiens_hsa05133 | 0.39131164 |
91 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.39004672 |
92 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.37476411 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.35123400 |
94 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.35080375 |
95 | RNA transport_Homo sapiens_hsa03013 | 0.35065219 |
96 | Legionellosis_Homo sapiens_hsa05134 | 0.34294925 |
97 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.33591534 |
98 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.33464898 |
99 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.32054033 |
100 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.31330251 |
101 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.30017177 |
102 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.28518310 |
103 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.27908378 |
104 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.27581502 |
105 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.26527037 |
106 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.26397313 |
107 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.26293903 |
108 | Endometrial cancer_Homo sapiens_hsa05213 | 0.25944524 |
109 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.25455745 |
110 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.25302433 |
111 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.24725990 |
112 | Long-term potentiation_Homo sapiens_hsa04720 | 0.24117885 |
113 | RNA degradation_Homo sapiens_hsa03018 | 0.23337915 |
114 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.16525885 |
115 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.13080962 |
116 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.11835499 |
117 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.10948617 |
118 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.09769088 |
119 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.04933093 |
120 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.04111695 |
121 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.01398372 |
122 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | -0.0016710 |