CD99L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.16912709
2vocalization behavior (GO:0071625)3.97843861
3synaptic vesicle maturation (GO:0016188)3.89252868
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.86961034
5locomotory exploration behavior (GO:0035641)3.63960417
6synaptic vesicle exocytosis (GO:0016079)3.60433750
7layer formation in cerebral cortex (GO:0021819)3.55765043
8glutamate secretion (GO:0014047)3.50861696
9neuron cell-cell adhesion (GO:0007158)3.50797518
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.49799655
11cerebellar granule cell differentiation (GO:0021707)3.49363699
12positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.47086456
13cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.44251828
14proline transport (GO:0015824)3.43949655
15regulation of synaptic vesicle exocytosis (GO:2000300)3.41355487
16activation of protein kinase A activity (GO:0034199)3.33139612
17regulation of glutamate receptor signaling pathway (GO:1900449)3.32898938
18protein localization to synapse (GO:0035418)3.32248445
19regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.29982929
20neuronal ion channel clustering (GO:0045161)3.29858067
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.28690142
22cell communication by electrical coupling (GO:0010644)3.27728717
23regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.22789038
24membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.22180438
25neurotransmitter secretion (GO:0007269)3.22155425
26positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.21563330
27regulation of ARF protein signal transduction (GO:0032012)3.21368035
28exploration behavior (GO:0035640)3.21107222
29neuron recognition (GO:0008038)3.18570547
30regulation of synapse structural plasticity (GO:0051823)3.17048303
31amino acid import (GO:0043090)3.15289578
32L-amino acid import (GO:0043092)3.12665539
33synaptic vesicle docking involved in exocytosis (GO:0016081)3.08979264
34neuronal action potential propagation (GO:0019227)3.08491831
35cerebellar Purkinje cell layer development (GO:0021680)3.07132505
36cytoskeletal anchoring at plasma membrane (GO:0007016)3.06467028
37cellular potassium ion homeostasis (GO:0030007)3.06067972
38regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.05080408
39regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.04605184
40axonal fasciculation (GO:0007413)3.02237780
41positive regulation of dendritic spine development (GO:0060999)3.01211749
42regulation of synaptic plasticity (GO:0048167)3.00783676
43regulation of synaptic vesicle transport (GO:1902803)3.00443919
44sodium ion export (GO:0071436)2.97261873
45regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.96147096
46cell communication involved in cardiac conduction (GO:0086065)2.92412436
47regulation of synapse maturation (GO:0090128)2.91661031
48gamma-aminobutyric acid transport (GO:0015812)2.88587981
49dendrite morphogenesis (GO:0048813)2.86875610
50positive regulation of neurotransmitter transport (GO:0051590)2.86709330
51regulation of neurotransmitter secretion (GO:0046928)2.84087531
52positive regulation of potassium ion transmembrane transport (GO:1901381)2.81372332
53dendritic spine morphogenesis (GO:0060997)2.79210720
54ionotropic glutamate receptor signaling pathway (GO:0035235)2.79011313
55regulation of neuronal synaptic plasticity (GO:0048168)2.78973240
56regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.78666053
57positive regulation of neurotransmitter secretion (GO:0001956)2.78615782
58neurotransmitter-gated ion channel clustering (GO:0072578)2.78173116
59positive regulation of membrane potential (GO:0045838)2.75733550
60membrane depolarization during action potential (GO:0086010)2.75317691
61dendritic spine organization (GO:0097061)2.74301773
62regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.71502383
63plasma membrane repair (GO:0001778)2.70347974
64regulation of long-term neuronal synaptic plasticity (GO:0048169)2.69350495
65regulation of voltage-gated calcium channel activity (GO:1901385)2.66205888
66regulation of membrane repolarization (GO:0060306)2.65240182
67cell migration in hindbrain (GO:0021535)2.64758915
68G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.64606211
69regulation of dendritic spine development (GO:0060998)2.63647348
70cellular sodium ion homeostasis (GO:0006883)2.61718147
71regulation of neurotransmitter transport (GO:0051588)2.61696156
72neurotransmitter transport (GO:0006836)2.60525244
73pyrimidine nucleobase catabolic process (GO:0006208)2.60221821
74regulation of cell communication by electrical coupling (GO:0010649)2.60031470
75glutamate receptor signaling pathway (GO:0007215)2.59778518
76alanine transport (GO:0032328)2.57612182
77positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.56404865
78negative regulation of dendrite morphogenesis (GO:0050774)2.55464292
79glycine transport (GO:0015816)2.55319511
80mating behavior (GO:0007617)2.54913045
81innervation (GO:0060384)2.52349780
82positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.52181233
83synapse assembly (GO:0007416)2.51799315
84axon extension (GO:0048675)2.51238665
85regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.50440937
86regulation of calcium ion transmembrane transporter activity (GO:1901019)2.50413975
87regulation of calcium ion transmembrane transport (GO:1903169)2.50413975
88neuron-neuron synaptic transmission (GO:0007270)2.49826264
89sarcoplasmic reticulum calcium ion transport (GO:0070296)2.49169206
90vesicle transport along microtubule (GO:0047496)2.48988511
91synaptic transmission, glutamatergic (GO:0035249)2.48965099
92organelle transport along microtubule (GO:0072384)2.48388874
93cellular response to catecholamine stimulus (GO:0071870)2.47565961
94cellular response to monoamine stimulus (GO:0071868)2.47565961
95cerebellar Purkinje cell differentiation (GO:0021702)2.46622651
96positive regulation of potassium ion transport (GO:0043268)2.45879534
97regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.45717426
98synapse organization (GO:0050808)2.44638230
99potassium ion import (GO:0010107)2.44354404
100postsynaptic membrane organization (GO:0001941)2.44296003
101potassium ion homeostasis (GO:0055075)2.42728344
102regulation of neurotransmitter levels (GO:0001505)2.42547014
103protein localization to endosome (GO:0036010)2.42151440
104central nervous system myelination (GO:0022010)2.42126320
105axon ensheathment in central nervous system (GO:0032291)2.42126320
106regulation of cAMP-dependent protein kinase activity (GO:2000479)2.41694732
107regulation of vesicle fusion (GO:0031338)2.41141244
108acidic amino acid transport (GO:0015800)2.41044713
109long-term memory (GO:0007616)2.40349884
110nucleobase catabolic process (GO:0046113)2.40146217
111neuromuscular process controlling posture (GO:0050884)2.38992271
112gamma-aminobutyric acid signaling pathway (GO:0007214)2.38706072
113response to gravity (GO:0009629)2.38262978
114establishment of nucleus localization (GO:0040023)2.37187382
115negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.36945339
116detection of calcium ion (GO:0005513)2.36513327
117calcium-mediated signaling using intracellular calcium source (GO:0035584)2.35943763
118regulation of potassium ion transmembrane transport (GO:1901379)2.35193834
119regulation of synaptic transmission (GO:0050804)2.35021672
120regulation of excitatory postsynaptic membrane potential (GO:0060079)2.34783205
121neuromuscular process controlling balance (GO:0050885)2.34157921
122negative regulation of potassium ion transmembrane transport (GO:1901380)2.34055589
123negative regulation of synaptic transmission, GABAergic (GO:0032229)2.32923465
124transmission of nerve impulse (GO:0019226)2.32795874
125positive regulation of synapse maturation (GO:0090129)2.32763195
126chondroitin sulfate catabolic process (GO:0030207)2.32638112
127neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.32195602
128positive regulation of synaptic transmission, GABAergic (GO:0032230)2.32118431
129vesicle docking involved in exocytosis (GO:0006904)2.32099388
130regulation of postsynaptic membrane potential (GO:0060078)2.31771585
131positive regulation of dendrite development (GO:1900006)2.31421854
132axon cargo transport (GO:0008088)2.30655824
133regulation of dendritic spine morphogenesis (GO:0061001)2.29134443
134synaptic vesicle endocytosis (GO:0048488)2.28755486

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.31777889
2THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.03255169
3GBX2_23144817_ChIP-Seq_PC3_Human2.88470784
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.86974249
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.78753694
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.60577365
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.57316906
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.57316906
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39280538
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.38617905
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.37320952
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36080525
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.35171032
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.28069351
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.27675519
16EED_16625203_ChIP-ChIP_MESCs_Mouse2.23187144
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.05069765
18AR_21572438_ChIP-Seq_LNCaP_Human2.01618763
19PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.01547864
20DROSHA_22980978_ChIP-Seq_HELA_Human2.00110740
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.97114260
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.93601825
23REST_21632747_ChIP-Seq_MESCs_Mouse1.92721436
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90360457
25RARG_19884340_ChIP-ChIP_MEFs_Mouse1.86667676
26CDX2_19796622_ChIP-Seq_MESCs_Mouse1.81386689
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.74658297
28LXR_22292898_ChIP-Seq_THP-1_Human1.65618827
29REST_18959480_ChIP-ChIP_MESCs_Mouse1.62652534
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.62201100
31TAF15_26573619_Chip-Seq_HEK293_Human1.60731620
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.57469309
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.54603810
34SMAD4_21799915_ChIP-Seq_A2780_Human1.52195638
35TET1_21490601_ChIP-Seq_MESCs_Mouse1.51118598
36EP300_21415370_ChIP-Seq_HL-1_Mouse1.47126156
37PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.45783410
38* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.45623931
39NR3C1_23031785_ChIP-Seq_PC12_Mouse1.43688956
40ZNF274_21170338_ChIP-Seq_K562_Hela1.42709371
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42594747
42PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.42261576
43KDM2B_26808549_Chip-Seq_SUP-B15_Human1.41494575
44TRIM28_21343339_ChIP-Seq_HEK293_Human1.36141834
45IKZF1_21737484_ChIP-ChIP_HCT116_Human1.35735645
46ERG_21242973_ChIP-ChIP_JURKAT_Human1.34931017
47MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33871099
48ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.32177749
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.30119338
50ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.28962036
51SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28720249
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28526114
53ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28433386
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.28341401
55RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.27310210
56ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.26952480
57SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.25967087
58ESR1_20079471_ChIP-ChIP_T-47D_Human1.25094277
59RING1B_27294783_Chip-Seq_ESCs_Mouse1.23509945
60RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.23071496
61EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22233963
62CTCF_27219007_Chip-Seq_Bcells_Human1.21683763
63* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21614724
64* AHR_22903824_ChIP-Seq_MCF-7_Human1.21268990
65OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.19973059
66* ARNT_22903824_ChIP-Seq_MCF-7_Human1.19452160
67WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.19301520
68P300_19829295_ChIP-Seq_ESCs_Human1.18226855
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17768942
70TOP2B_26459242_ChIP-Seq_MCF-7_Human1.17632416
71AR_25329375_ChIP-Seq_VCAP_Human1.17627668
72SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.15928979
73CLOCK_20551151_ChIP-Seq_293T_Human1.15841448
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.14905557
75TBX20_22080862_ChIP-Seq_HEART_Mouse1.14384642
76TBX20_22328084_ChIP-Seq_HEART_Mouse1.14384642
77AR_19668381_ChIP-Seq_PC3_Human1.11955271
78ZFP281_27345836_Chip-Seq_ESCs_Mouse1.11845754
79SMAD3_21741376_ChIP-Seq_EPCs_Human1.11804555
80PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.10463137
81PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.09229766
82CBX2_27304074_Chip-Seq_ESCs_Mouse1.09035179
83DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08048383
84AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07292048
85TP53_23651856_ChIP-Seq_MEFs_Mouse1.07111828
86SMAD_19615063_ChIP-ChIP_OVARY_Human1.06702507
87RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.06612387
88ZFP57_27257070_Chip-Seq_ESCs_Mouse1.06360927
89PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.05066672
90BCAT_22108803_ChIP-Seq_LS180_Human1.04170168
91ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04074809
92TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.03571923
93STAT3_23295773_ChIP-Seq_U87_Human1.03484284
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03236597
95CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03182309
96DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02676189
97BMI1_23680149_ChIP-Seq_NPCS_Mouse1.02236916
98CTNNB1_20460455_ChIP-Seq_HCT116_Human1.02065209
99NRF2_20460467_ChIP-Seq_MEFs_Mouse1.01743586
100NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.01743586
101SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01132253
102UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00996148
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00921496
104SMAD4_21741376_ChIP-Seq_HESCs_Human1.00033735
105RING1B_27294783_Chip-Seq_NPCs_Mouse0.99883580
106BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99839029
107KDM2B_26808549_Chip-Seq_K562_Human0.99544188
108TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.99516240
109TP53_18474530_ChIP-ChIP_U2OS_Human0.99050936
110* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.95551574
111EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.95473766
112YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94477460
113TP53_20018659_ChIP-ChIP_R1E_Mouse0.93380837
114NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92680585
115SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91832082
116P300_27058665_Chip-Seq_ZR-75-30cells_Human0.91709878
117KDM2B_26808549_Chip-Seq_DND41_Human0.91638656
118CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90846964
119MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.90042020
120RXR_22108803_ChIP-Seq_LS180_Human0.89999951
121EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.89709207
122TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.89643134
123TP53_16413492_ChIP-PET_HCT116_Human0.89549972
124POU3F2_20337985_ChIP-ChIP_501MEL_Human0.89449870
125ESR2_21235772_ChIP-Seq_MCF-7_Human0.89003597
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88748954
127SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88464257
128* RUNX2_22187159_ChIP-Seq_PCA_Human0.87457341
129GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86929007
130TCF4_23295773_ChIP-Seq_U87_Human0.86911649
131SMC4_20622854_ChIP-Seq_HELA_Human0.86871131
132NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.86487467
133TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86381862
134GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84308301
135GATA2_21666600_ChIP-Seq_HMVEC_Human0.84135132
136ELK3_25401928_ChIP-Seq_HUVEC_Human0.83965215
137SMC1_22415368_ChIP-Seq_MEFs_Mouse0.82415131
138KDM2B_26808549_Chip-Seq_JURKAT_Human0.82397592
139ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.81976895
140RACK7_27058665_Chip-Seq_MCF-7_Human0.81469574
141CREB1_26743006_Chip-Seq_LNCaP_Human0.80117392
142KLF4_19829295_ChIP-Seq_ESCs_Human0.78170665

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.32097414
2MP0003880_abnormal_central_pattern3.33163469
3MP0003635_abnormal_synaptic_transmissio2.99423028
4MP0004270_analgesia2.91764042
5MP0002837_dystrophic_cardiac_calcinosis2.87073597
6MP0000751_myopathy2.81049739
7MP0001968_abnormal_touch/_nociception2.41623266
8MP0009745_abnormal_behavioral_response2.37723462
9MP0002063_abnormal_learning/memory/cond2.37293786
10MP0002064_seizures2.23019210
11MP0009046_muscle_twitch2.21007052
12MP0006276_abnormal_autonomic_nervous2.19925214
13MP0002734_abnormal_mechanical_nocicepti2.19088177
14MP0009780_abnormal_chondrocyte_physiolo2.12919271
15MP0004858_abnormal_nervous_system2.10388744
16MP0002572_abnormal_emotion/affect_behav1.98378815
17MP0002735_abnormal_chemical_nociception1.96078801
18MP0002272_abnormal_nervous_system1.93884338
19MP0005423_abnormal_somatic_nervous1.91813479
20MP0004145_abnormal_muscle_electrophysio1.91811625
21MP0002736_abnormal_nociception_after1.86453056
22MP0001440_abnormal_grooming_behavior1.85644830
23MP0003329_amyloid_beta_deposits1.84190958
24MP0000920_abnormal_myelination1.78007990
25MP0003122_maternal_imprinting1.77854478
26MP0002909_abnormal_adrenal_gland1.77544554
27MP0001501_abnormal_sleep_pattern1.75196078
28MP0002733_abnormal_thermal_nociception1.74696835
29MP0003705_abnormal_hypodermis_morpholog1.73469059
30MP0004215_abnormal_myocardial_fiber1.72240185
31MP0001486_abnormal_startle_reflex1.71923698
32MP0000013_abnormal_adipose_tissue1.69437852
33MP0004130_abnormal_muscle_cell1.67369126
34MP0001958_emphysema1.62236311
35MP0000778_abnormal_nervous_system1.60341633
36MP0002184_abnormal_innervation1.60306203
37MP0002067_abnormal_sensory_capabilities1.58644117
38MP0001970_abnormal_pain_threshold1.56624783
39MP0004036_abnormal_muscle_relaxation1.54289743
40MP0000749_muscle_degeneration1.48687772
41MP0003279_aneurysm1.46768109
42MP0004084_abnormal_cardiac_muscle1.44723651
43MP0004924_abnormal_behavior1.43802825
44MP0005386_behavior/neurological_phenoty1.43802825
45MP0005058_abnormal_lysosome_morphology1.42724290
46MP0008569_lethality_at_weaning1.42025355
47MP0004510_myositis1.38748439
48MP0002557_abnormal_social/conspecific_i1.34741697
49MP0003646_muscle_fatigue1.34088711
50MP0001984_abnormal_olfaction1.32599307
51MP0002822_catalepsy1.29739153
52MP0004811_abnormal_neuron_physiology1.29086913
53MP0005645_abnormal_hypothalamus_physiol1.27727537
54MP0000955_abnormal_spinal_cord1.26866053
55MP0003075_altered_response_to1.26811229
56MP0000747_muscle_weakness1.26626956
57MP0004085_abnormal_heartbeat1.26551105
58MP0004484_altered_response_of1.26268718
59MP0004233_abnormal_muscle_weight1.25665011
60MP0005620_abnormal_muscle_contractility1.25214543
61MP0003172_abnormal_lysosome_physiology1.24565767
62MP0003137_abnormal_impulse_conducting1.24082340
63MP0003633_abnormal_nervous_system1.15483704
64MP0005623_abnormal_meninges_morphology1.15279992
65MP0001299_abnormal_eye_distance/1.13552095
66MP0002066_abnormal_motor_capabilities/c1.11068046
67MP0002972_abnormal_cardiac_muscle1.10362575
68MP0005646_abnormal_pituitary_gland1.10249942
69MP0004087_abnormal_muscle_fiber1.09726472
70MP0002882_abnormal_neuron_morphology1.09602844
71MP0002295_abnormal_pulmonary_circulatio1.02377298
72MP0005330_cardiomyopathy1.01089729
73MP0001348_abnormal_lacrimal_gland0.99649786
74MP0001502_abnormal_circadian_rhythm0.98538199
75MP0000759_abnormal_skeletal_muscle0.98149105
76MP0004272_abnormal_basement_membrane0.94244195
77MP0003690_abnormal_glial_cell0.93095962
78MP0005187_abnormal_penis_morphology0.92174181
79MP0003632_abnormal_nervous_system0.92113562
80MP0002106_abnormal_muscle_physiology0.91340976
81MP0005369_muscle_phenotype0.89848385
82MP0003631_nervous_system_phenotype0.89709284
83MP0003634_abnormal_glial_cell0.89524121
84MP0004885_abnormal_endolymph0.89361535
85MP0002108_abnormal_muscle_morphology0.88587380
86MP0001529_abnormal_vocalization0.88084238
87MP0002090_abnormal_vision0.87831672
88MP0005535_abnormal_body_temperature0.87411891
89MP0008775_abnormal_heart_ventricle0.86776778
90MP0000604_amyloidosis0.85480685
91MP0002269_muscular_atrophy0.85469195
92MP0002971_abnormal_brown_adipose0.85163528
93MP0003879_abnormal_hair_cell0.84804039
94MP0006138_congestive_heart_failure0.84201323
95MP0004142_abnormal_muscle_tone0.83882283
96MP0002332_abnormal_exercise_endurance0.82950069
97MP0005503_abnormal_tendon_morphology0.82121408
98MP0000003_abnormal_adipose_tissue0.82006229
99MP0005257_abnormal_intraocular_pressure0.81338083
100MP0005167_abnormal_blood-brain_barrier0.81260830
101MP0000750_abnormal_muscle_regeneration0.81039000
102MP0002069_abnormal_eating/drinking_beha0.80080724
103MP0010386_abnormal_urinary_bladder0.79786502
104MP0001905_abnormal_dopamine_level0.79275333
105MP0002152_abnormal_brain_morphology0.78773283
106MP0008961_abnormal_basal_metabolism0.78046443
107MP0002896_abnormal_bone_mineralization0.77841030
108MP0001177_atelectasis0.75058946
109MP0003091_abnormal_cell_migration0.74263127
110MP0001544_abnormal_cardiovascular_syste0.73089436
111MP0005385_cardiovascular_system_phenoty0.73089436
112MP0005165_increased_susceptibility_to0.72855405
113MP0003123_paternal_imprinting0.71063285
114MP0003787_abnormal_imprinting0.70567251
115MP0005595_abnormal_vascular_smooth0.70434845
116MP0005375_adipose_tissue_phenotype0.70351092
117MP0000534_abnormal_ureter_morphology0.68828405
118MP0010368_abnormal_lymphatic_system0.68393354
119MP0002229_neurodegeneration0.68384117
120MP0005670_abnormal_white_adipose0.68033014
121MP0000230_abnormal_systemic_arterial0.67050927
122MP0000569_abnormal_digit_pigmentation0.65404121
123MP0003283_abnormal_digestive_organ0.64541152
124MP0008874_decreased_physiological_sensi0.63651328
125MP0008438_abnormal_cutaneous_collagen0.63143385

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.43103817
2Myokymia (HP:0002411)4.25273896
3Focal seizures (HP:0007359)3.79670963
4Visual hallucinations (HP:0002367)3.47122747
5Atonic seizures (HP:0010819)3.39996756
6Protrusio acetabuli (HP:0003179)3.23695146
7Exercise-induced myalgia (HP:0003738)3.19238764
8Action tremor (HP:0002345)3.11701065
9Pheochromocytoma (HP:0002666)3.05342436
10Sudden death (HP:0001699)3.03504324
11Obstructive sleep apnea (HP:0002870)3.00880264
12Abnormality of binocular vision (HP:0011514)3.00633277
13Diplopia (HP:0000651)3.00633277
14Premature rupture of membranes (HP:0001788)3.00410711
15Supranuclear gaze palsy (HP:0000605)2.99454495
16Epileptic encephalopathy (HP:0200134)2.95094337
17Termporal pattern (HP:0011008)2.91506449
18Insidious onset (HP:0003587)2.91506449
19Absence seizures (HP:0002121)2.90375550
20Generalized tonic-clonic seizures (HP:0002069)2.81633349
21Myotonia (HP:0002486)2.81189661
22Ankle clonus (HP:0011448)2.80450825
23Progressive cerebellar ataxia (HP:0002073)2.78665364
24Febrile seizures (HP:0002373)2.77123790
25Upper limb amyotrophy (HP:0009129)2.64037881
26Distal upper limb amyotrophy (HP:0007149)2.64037881
27Muscle fiber inclusion bodies (HP:0100299)2.58576146
28Tetraplegia (HP:0002445)2.57921332
29Muscle hypertrophy of the lower extremities (HP:0008968)2.57860404
30Calf muscle hypertrophy (HP:0008981)2.56488922
31Dialeptic seizures (HP:0011146)2.55334282
32Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.54324268
33Prolonged QT interval (HP:0001657)2.50992084
34Abnormality of the calf musculature (HP:0001430)2.49842588
35Abnormal eating behavior (HP:0100738)2.49536279
36Nemaline bodies (HP:0003798)2.48701735
37Hand muscle atrophy (HP:0009130)2.48100119
38Neuroendocrine neoplasm (HP:0100634)2.48065227
39Exercise-induced muscle cramps (HP:0003710)2.46087223
40Hyporeflexia of lower limbs (HP:0002600)2.46043356
41Neurofibrillary tangles (HP:0002185)2.45214815
42Anxiety (HP:0000739)2.42864569
43Cerebral inclusion bodies (HP:0100314)2.40428883
44Difficulty running (HP:0009046)2.37941911
45Depression (HP:0000716)2.36988462
46Cerebral aneurysm (HP:0004944)2.36380634
47Spinal rigidity (HP:0003306)2.35995043
48Insomnia (HP:0100785)2.35554390
49Abnormality of the corticospinal tract (HP:0002492)2.35498869
50Urinary bladder sphincter dysfunction (HP:0002839)2.35165592
51Syncope (HP:0001279)2.34700619
52Apathy (HP:0000741)2.34045335
53Atrial fibrillation (HP:0005110)2.32657369
54Craniofacial dystonia (HP:0012179)2.32278889
55Polyphagia (HP:0002591)2.30993891
56Ventricular fibrillation (HP:0001663)2.29482910
57Impaired vibration sensation in the lower limbs (HP:0002166)2.29185444
58Primary atrial arrhythmia (HP:0001692)2.29133060
59Vertebral compression fractures (HP:0002953)2.27143683
60Increased variability in muscle fiber diameter (HP:0003557)2.26446896
61Round ear (HP:0100830)2.25623196
62Nuclear cataract (HP:0100018)2.25464280
63Urinary urgency (HP:0000012)2.24760210
64Akinesia (HP:0002304)2.23470022
65Agitation (HP:0000713)2.23193286
66Aplasia involving bones of the extremities (HP:0009825)2.21555365
67Aplasia involving bones of the upper limbs (HP:0009823)2.21555365
68Aplasia of the phalanges of the hand (HP:0009802)2.21555365
69Increased connective tissue (HP:0009025)2.21439895
70Neuronal loss in central nervous system (HP:0002529)2.20275803
71Dysdiadochokinesis (HP:0002075)2.20045708
72Annular pancreas (HP:0001734)2.17878889
73Vascular tortuosity (HP:0004948)2.17573993
74Abnormal EKG (HP:0003115)2.15882687
75Centrally nucleated skeletal muscle fibers (HP:0003687)2.14537217
76Rigidity (HP:0002063)2.14474059
77Lower limb muscle weakness (HP:0007340)2.14443744
78Dysostosis multiplex (HP:0000943)2.12124216
79Broad-based gait (HP:0002136)2.11559952
80Asymmetric septal hypertrophy (HP:0001670)2.11370063
81Supraventricular tachycardia (HP:0004755)2.11159401
82Truncal ataxia (HP:0002078)2.10440794
83Slender build (HP:0001533)2.10334322
84Diminished motivation (HP:0000745)2.10219874
85Impaired social interactions (HP:0000735)2.10060507
86Abnormal social behavior (HP:0012433)2.10060507
87EMG: myopathic abnormalities (HP:0003458)2.08651787
88Hypoventilation (HP:0002791)2.08418694
89Supraventricular arrhythmia (HP:0005115)2.08238261
90Distal lower limb amyotrophy (HP:0008944)2.07322649
91Poor eye contact (HP:0000817)2.06642526
92Torticollis (HP:0000473)2.04408177
93Oligomenorrhea (HP:0000876)2.03878481
94Abnormality of liposaccharide metabolism (HP:0010968)2.03484419
95Abnormality of glycosphingolipid metabolism (HP:0004343)2.03484419
96Abnormality of glycolipid metabolism (HP:0010969)2.03484419
97Mutism (HP:0002300)2.01280963
98Mildly elevated creatine phosphokinase (HP:0008180)2.01252099
99Hyperventilation (HP:0002883)2.01047697
100Abnormal atrioventricular conduction (HP:0005150)2.00494388
101Urinary glycosaminoglycan excretion (HP:0003541)2.00407677
102Mucopolysacchariduria (HP:0008155)2.00407677
103Arterial tortuosity (HP:0005116)1.98657287
104Shallow orbits (HP:0000586)1.98493675
105Excessive salivation (HP:0003781)1.97193556
106Drooling (HP:0002307)1.97193556
107Progressive inability to walk (HP:0002505)1.96858442
108Bundle branch block (HP:0011710)1.96057661
109Genetic anticipation (HP:0003743)1.95927367
110Amblyopia (HP:0000646)1.95876454
111Lower limb amyotrophy (HP:0007210)1.95578051
112Postural instability (HP:0002172)1.95320292
113Muscle fiber splitting (HP:0003555)1.94457691
114Abnormality of polysaccharide metabolism (HP:0011012)1.94431928
115Abnormality of glycosaminoglycan metabolism (HP:0004371)1.94431928
116Abnormality of mucopolysaccharide metabolism (HP:0011020)1.94431928
117Abnormality of the lower motor neuron (HP:0002366)1.94200979
118Failure to thrive in infancy (HP:0001531)1.92993710
119Type 1 muscle fiber predominance (HP:0003803)1.92639965
120Muscle stiffness (HP:0003552)1.92272357
121Myoglobinuria (HP:0002913)1.92021364
122Heart block (HP:0012722)1.91164887
123Dysmetria (HP:0001310)1.90581233
124Broad metatarsal (HP:0001783)1.90566073
125Mitral stenosis (HP:0001718)1.90125724
126Epileptiform EEG discharges (HP:0011182)1.88200723
127Abnormality of pain sensation (HP:0010832)1.87907290
128Impaired pain sensation (HP:0007328)1.87907290
129Dysmetric saccades (HP:0000641)1.86460803
130Turricephaly (HP:0000262)1.86261819
131Scanning speech (HP:0002168)1.85460899
132Papilledema (HP:0001085)1.85228173
133Ventricular arrhythmia (HP:0004308)1.85109966
134Fetal akinesia sequence (HP:0001989)1.85078871
135Frequent falls (HP:0002359)1.84915603
136Rapidly progressive (HP:0003678)1.83971309
137Foot dorsiflexor weakness (HP:0009027)1.83619834
138Abnormality of skeletal muscle fiber size (HP:0012084)1.83499768
139Distal lower limb muscle weakness (HP:0009053)1.83387373
140Spastic gait (HP:0002064)1.83296105
141Bradykinesia (HP:0002067)1.83175502
142Wormian bones (HP:0002645)1.83093240
143Bladder diverticulum (HP:0000015)1.82752599
144Bradycardia (HP:0001662)1.82234121
145Abnormality of dentin (HP:0010299)1.80901599
146Megalencephaly (HP:0001355)1.80378510
147Ketoacidosis (HP:0001993)1.78878142
148Hypercortisolism (HP:0001578)1.78274969
149Hyperthyroidism (HP:0000836)1.77220203
150Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.74373163
151Degeneration of the lateral corticospinal tracts (HP:0002314)1.74373163
152Buphthalmos (HP:0000557)1.72655042
153Hemiparesis (HP:0001269)1.72275458
154Neoplasm of the peripheral nervous system (HP:0100007)1.71908561
155Intention tremor (HP:0002080)1.69519138
156Focal dystonia (HP:0004373)1.69117029

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.34831912
2MARK13.26756553
3MAP3K42.73944565
4MAP3K92.73001105
5PHKG22.72339810
6PHKG12.72339810
7MINK12.50967789
8MAP2K42.23701789
9EPHA42.09394766
10MAP2K72.05162191
11LMTK22.04940009
12NTRK12.00940125
13PAK61.87760935
14NTRK21.69761457
15DAPK21.64885220
16MAP3K121.63351230
17KSR21.59425701
18LATS21.58205397
19TESK11.53548836
20CASK1.51340265
21PAK31.41955308
22MAPK131.33796697
23CAMKK11.30334594
24FER1.29409073
25TTN1.27999620
26TRIB31.26306255
27PRKD31.23702666
28CDK51.21954922
29RET1.19610496
30KSR11.14270297
31PLK21.14019291
32ICK1.11265178
33MOS1.11192053
34GRK51.09830413
35MAP3K131.09239357
36CAMK1G1.07294742
37STK381.04352417
38SGK4941.03280639
39SGK2231.03280639
40MAP3K21.03089108
41ERBB31.03060813
42OBSCN0.99377897
43CAMK2A0.97268633
44PRKCG0.92968926
45WNK30.91820518
46PTK20.90416317
47UHMK10.88558898
48CAMKK20.87481488
49RIPK10.87235810
50PKN20.86831353
51PIK3CA0.85532971
52PDK40.85490194
53PDK30.85490194
54ARAF0.85405639
55PRKCH0.83247958
56PINK10.83222328
57PDGFRA0.81003912
58INSRR0.80420474
59GRK70.78705179
60MAP2K10.78637426
61EPHB20.78250819
62SGK30.77231912
63SGK20.76770678
64DDR20.75567304
65RIPK40.74743800
66MAP3K110.74586069
67PTK2B0.74291335
68PKN10.73900787
69MYLK0.73820923
70WNK10.72623107
71ERN10.70624637
72SIK20.70471956
73ROCK10.70422426
74MAPK120.70240790
75NEK10.70223053
76PRKCE0.69599183
77RPS6KA20.69576183
78DAPK30.69256795
79CAMK2D0.69053586
80WNK40.68754348
81CDK140.68626019
82CSNK1G20.67712070
83PRPF4B0.67703639
84EPHB10.65729767
85PDK10.65303923
86TYRO30.63301804
87CAMK1D0.62726959
88TAOK20.62337670
89STK390.61900568
90FGFR20.61846777
91LIMK10.61549337
92CDK180.61364843
93CAMK10.61187217
94ROCK20.60890966
95PDPK10.60643992
96CDK150.60415599
97CAMK2G0.60292295
98PNCK0.59781345
99MAP3K10.59090726
100MAP3K70.58759779
101CAMK2B0.58307030
102PRKCZ0.57541066
103DMPK0.57456323
104PRKD20.56419304
105OXSR10.55698361
106PDK20.54745372
107SIK10.54677082
108CAMK40.54405388
109SGK10.54083200
110STK110.52643476
111TNIK0.52458233
112ADRBK10.52232599
113MARK20.51681856
114MAPK100.51271650
115PAK20.51107044
116CDC42BPA0.51021400
117DYRK1A0.50874337
118BRAF0.49883205
119DAPK10.49018916
120CDK11A0.47543675
121PRKG20.43078063
122MAP2K60.42548889
123RPS6KA30.41839175
124PRKD10.41715479
125ABL20.41613720
126PRKAA10.37187763
127MAPK70.36839728
128BRSK10.35711696
129ALK0.35470276

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.60912816
2Synaptic vesicle cycle_Homo sapiens_hsa047212.40608275
3GABAergic synapse_Homo sapiens_hsa047272.13593189
4Circadian entrainment_Homo sapiens_hsa047131.97970015
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.93464654
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.91179426
7Olfactory transduction_Homo sapiens_hsa047401.84040456
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.74403429
9Morphine addiction_Homo sapiens_hsa050321.72097606
10Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.66255883
11Long-term potentiation_Homo sapiens_hsa047201.66194967
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.65161926
13Glutamatergic synapse_Homo sapiens_hsa047241.63522119
14Dopaminergic synapse_Homo sapiens_hsa047281.62974235
15Insulin secretion_Homo sapiens_hsa049111.59538222
16Salivary secretion_Homo sapiens_hsa049701.59340110
17Amphetamine addiction_Homo sapiens_hsa050311.56810109
18Renin secretion_Homo sapiens_hsa049241.56273645
19Cardiac muscle contraction_Homo sapiens_hsa042601.54187229
20Gastric acid secretion_Homo sapiens_hsa049711.51056761
21Dilated cardiomyopathy_Homo sapiens_hsa054141.49934794
22Vitamin B6 metabolism_Homo sapiens_hsa007501.49527667
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46476161
24Cholinergic synapse_Homo sapiens_hsa047251.44918735
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.40118305
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.39043859
27Oxytocin signaling pathway_Homo sapiens_hsa049211.38311017
28Taste transduction_Homo sapiens_hsa047421.34795463
29Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29312786
30Cocaine addiction_Homo sapiens_hsa050301.26215397
31Calcium signaling pathway_Homo sapiens_hsa040201.21532503
32Collecting duct acid secretion_Homo sapiens_hsa049661.20475638
33Gap junction_Homo sapiens_hsa045401.16953263
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.16823421
35Serotonergic synapse_Homo sapiens_hsa047261.16389341
36Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.15833225
37GnRH signaling pathway_Homo sapiens_hsa049121.15104494
38Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.14873241
39Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.14456475
40Long-term depression_Homo sapiens_hsa047301.13975801
41Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.12821153
42Type II diabetes mellitus_Homo sapiens_hsa049301.11844347
43Butanoate metabolism_Homo sapiens_hsa006501.10434527
44Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.10131927
45Axon guidance_Homo sapiens_hsa043601.08545505
46Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.07576389
47Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.06927109
48Nitrogen metabolism_Homo sapiens_hsa009101.00599112
49cAMP signaling pathway_Homo sapiens_hsa040241.00143099
50Other glycan degradation_Homo sapiens_hsa005110.99211076
51Propanoate metabolism_Homo sapiens_hsa006400.98184107
52Estrogen signaling pathway_Homo sapiens_hsa049150.97649136
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94248898
54Fatty acid metabolism_Homo sapiens_hsa012120.93657734
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.91237881
56Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.90955875
57Fatty acid biosynthesis_Homo sapiens_hsa000610.90609006
58Melanogenesis_Homo sapiens_hsa049160.87573274
59Bile secretion_Homo sapiens_hsa049760.86378921
60Glioma_Homo sapiens_hsa052140.85698919
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.84646601
62Vibrio cholerae infection_Homo sapiens_hsa051100.84636240
63Insulin signaling pathway_Homo sapiens_hsa049100.82590527
64Glucagon signaling pathway_Homo sapiens_hsa049220.82590289
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.81606629
66Dorso-ventral axis formation_Homo sapiens_hsa043200.78474061
67Alzheimers disease_Homo sapiens_hsa050100.77323778
68Lysosome_Homo sapiens_hsa041420.77129903
69ErbB signaling pathway_Homo sapiens_hsa040120.73457704
70Oxidative phosphorylation_Homo sapiens_hsa001900.71609822
71VEGF signaling pathway_Homo sapiens_hsa043700.70696453
72ECM-receptor interaction_Homo sapiens_hsa045120.70081384
73Thyroid hormone synthesis_Homo sapiens_hsa049180.68287661
74Fatty acid degradation_Homo sapiens_hsa000710.67656692
75Pyruvate metabolism_Homo sapiens_hsa006200.67313004
76Arginine and proline metabolism_Homo sapiens_hsa003300.66459336
77Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65841323
78Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64642877
79Parkinsons disease_Homo sapiens_hsa050120.62913008
80Pancreatic secretion_Homo sapiens_hsa049720.61937920
81Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.60327010
82Inositol phosphate metabolism_Homo sapiens_hsa005620.59458434
83Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.59301419
84Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58997844
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.58892928
86Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.58500235
87Endocytosis_Homo sapiens_hsa041440.58401103
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57919997
89PPAR signaling pathway_Homo sapiens_hsa033200.57568036
90Prion diseases_Homo sapiens_hsa050200.55791505
91Arginine biosynthesis_Homo sapiens_hsa002200.55469707
92Phospholipase D signaling pathway_Homo sapiens_hsa040720.55187844
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54923104
94Ovarian steroidogenesis_Homo sapiens_hsa049130.54365244
95Phosphatidylinositol signaling system_Homo sapiens_hsa040700.52806997
96Endometrial cancer_Homo sapiens_hsa052130.52064255
97Amoebiasis_Homo sapiens_hsa051460.52018246
98AMPK signaling pathway_Homo sapiens_hsa041520.51656858
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.51038229
100Adipocytokine signaling pathway_Homo sapiens_hsa049200.49951581
101MAPK signaling pathway_Homo sapiens_hsa040100.49434501
102Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49232350
103mTOR signaling pathway_Homo sapiens_hsa041500.47304667
104beta-Alanine metabolism_Homo sapiens_hsa004100.47218448
105Renal cell carcinoma_Homo sapiens_hsa052110.46314815
106Insulin resistance_Homo sapiens_hsa049310.45913879
107Proteoglycans in cancer_Homo sapiens_hsa052050.45101357
108Neurotrophin signaling pathway_Homo sapiens_hsa047220.43927822
109Ras signaling pathway_Homo sapiens_hsa040140.43742339
110Tight junction_Homo sapiens_hsa045300.43532352
111Choline metabolism in cancer_Homo sapiens_hsa052310.42967181
112Circadian rhythm_Homo sapiens_hsa047100.42843753
113Focal adhesion_Homo sapiens_hsa045100.42654418
114Histidine metabolism_Homo sapiens_hsa003400.41149217
115Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40123346
116Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39974791
117Rap1 signaling pathway_Homo sapiens_hsa040150.39675765
118Phenylalanine metabolism_Homo sapiens_hsa003600.39568902
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39147119
120Protein digestion and absorption_Homo sapiens_hsa049740.39113866
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38569356
122Pentose phosphate pathway_Homo sapiens_hsa000300.38508049
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.38186861
124Central carbon metabolism in cancer_Homo sapiens_hsa052300.38098270

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