CD99P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1centriole replication (GO:0007099)3.73125425
2indole-containing compound catabolic process (GO:0042436)3.49804107
3indolalkylamine catabolic process (GO:0046218)3.49804107
4tryptophan catabolic process (GO:0006569)3.49804107
5regulation of MHC class II biosynthetic process (GO:0045346)3.44807267
6DNA double-strand break processing (GO:0000729)3.39247982
7negative regulation of thymocyte apoptotic process (GO:0070244)3.36890217
8cellular extravasation (GO:0045123)3.36543315
9positive regulation of granulocyte differentiation (GO:0030854)3.35060272
10positive regulation of B cell differentiation (GO:0045579)3.33089141
11L-fucose catabolic process (GO:0042355)3.32283946
12fucose catabolic process (GO:0019317)3.32283946
13L-fucose metabolic process (GO:0042354)3.32283946
14DNA deamination (GO:0045006)3.25025406
15mast cell activation involved in immune response (GO:0002279)3.22962501
16mast cell degranulation (GO:0043303)3.22962501
17definitive hemopoiesis (GO:0060216)3.17291198
18centriole assembly (GO:0098534)3.17018446
19coenzyme catabolic process (GO:0009109)3.10030443
20endothelium development (GO:0003158)3.07356579
21negative regulation of granulocyte differentiation (GO:0030853)3.03891864
22regulation of granulocyte differentiation (GO:0030852)3.01968053
23platelet dense granule organization (GO:0060155)2.98834952
24multicellular organism reproduction (GO:0032504)2.98569210
25histone H3-K36 demethylation (GO:0070544)2.97469296
26purinergic nucleotide receptor signaling pathway (GO:0035590)2.92690688
27detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.91253005
28DNA methylation involved in gamete generation (GO:0043046)2.91079057
29positive regulation of gamma-delta T cell activation (GO:0046645)2.87259559
30response to pheromone (GO:0019236)2.86290032
31sulfation (GO:0051923)2.84361660
32negative regulation of translation, ncRNA-mediated (GO:0040033)2.82665271
33regulation of translation, ncRNA-mediated (GO:0045974)2.82665271
34negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.82665271
35regulation of thymocyte apoptotic process (GO:0070243)2.78881658
36tryptophan metabolic process (GO:0006568)2.78745926
37negative regulation of T cell apoptotic process (GO:0070233)2.76867423
38piRNA metabolic process (GO:0034587)2.76492939
39neutrophil activation involved in immune response (GO:0002283)2.75837509
40mast cell activation (GO:0045576)2.71052834
41indolalkylamine metabolic process (GO:0006586)2.68823861
42positive regulation of defense response to virus by host (GO:0002230)2.65814334
43positive regulation of prostaglandin secretion (GO:0032308)2.63525270
44L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.61033821
45epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.56283955
46negative regulation of telomere maintenance (GO:0032205)2.55630315
47histone H3-K9 methylation (GO:0051567)2.54250342
48modulation of growth of symbiont involved in interaction with host (GO:0044144)2.54077191
49regulation of growth of symbiont in host (GO:0044126)2.54077191
50negative regulation of growth of symbiont in host (GO:0044130)2.54077191
51negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.54077191
52thrombin receptor signaling pathway (GO:0070493)2.49715621
53behavioral response to nicotine (GO:0035095)2.48883577
54positive regulation of catecholamine secretion (GO:0033605)2.48182745
55mRNA cleavage (GO:0006379)2.47339929
56nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.46228766
57CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.45769469
58positive regulation of protein homodimerization activity (GO:0090073)2.45436096
59regulation of B cell differentiation (GO:0045577)2.44522326
60regulation of gamma-delta T cell activation (GO:0046643)2.43321170
61negative regulation of interleukin-1 beta production (GO:0032691)2.43027032
62negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.42058649
63regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.41690880
64meiotic chromosome segregation (GO:0045132)2.41251972
65double-strand break repair via homologous recombination (GO:0000724)2.40720924
66negative regulation of macrophage differentiation (GO:0045650)2.40627296
67recombinational repair (GO:0000725)2.39855009
68peptidyl-histidine modification (GO:0018202)2.39732148
69exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.39220137
70reciprocal DNA recombination (GO:0035825)2.39006361
71reciprocal meiotic recombination (GO:0007131)2.39006361
72kidney morphogenesis (GO:0060993)2.37040892
73cellular biogenic amine catabolic process (GO:0042402)2.36164655
74amine catabolic process (GO:0009310)2.36164655
75CD4-positive, alpha-beta T cell activation (GO:0035710)2.36150326
76positive regulation of icosanoid secretion (GO:0032305)2.35063651
77ADP metabolic process (GO:0046031)2.34887166
78negative regulation of macroautophagy (GO:0016242)2.33816282
79rRNA catabolic process (GO:0016075)2.32823375
80positive regulation of toll-like receptor signaling pathway (GO:0034123)2.32346366
81regulation of hippo signaling (GO:0035330)2.32222123
82DNA demethylation (GO:0080111)2.32100095
83regulation of posttranscriptional gene silencing (GO:0060147)2.32001999
84regulation of gene silencing by miRNA (GO:0060964)2.32001999
85regulation of gene silencing by RNA (GO:0060966)2.32001999
86tongue development (GO:0043586)2.31574104
87regulation of interleukin-6 biosynthetic process (GO:0045408)2.30995272
88regulation of oxidative stress-induced neuron death (GO:1903203)2.30235912
89hematopoietic stem cell proliferation (GO:0071425)2.30148664
90establishment of protein localization to Golgi (GO:0072600)2.29289000
91ventricular system development (GO:0021591)2.29213056
92negative regulation of DNA-dependent DNA replication (GO:2000104)2.28671789
93response to nitrosative stress (GO:0051409)2.28187357
94regulation of gamma-delta T cell differentiation (GO:0045586)2.28141310
95sphingosine metabolic process (GO:0006670)2.27976957
96regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.26943946
97positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.26943946
98negative regulation of phagocytosis (GO:0050765)2.26667326
99negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.24451561
100negative regulation of T-helper cell differentiation (GO:0045623)2.24451561

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.34381992
2BP1_19119308_ChIP-ChIP_Hs578T_Human4.27478166
3IRF8_22096565_ChIP-ChIP_GC-B_Human4.05501522
4ZNF274_21170338_ChIP-Seq_K562_Hela3.31568660
5IGF1R_20145208_ChIP-Seq_DFB_Human3.28346081
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.16480179
7SCL_19346495_ChIP-Seq_HPC-7_Human2.75441868
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.48150965
9LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.32546288
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.24806327
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16415758
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.16298355
13GBX2_23144817_ChIP-Seq_PC3_Human2.16021479
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.06154136
15ER_23166858_ChIP-Seq_MCF-7_Human1.98618676
16VDR_22108803_ChIP-Seq_LS180_Human1.93728292
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86643855
18NOTCH1_21737748_ChIP-Seq_TLL_Human1.85810588
19FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.80835532
20IRF1_19129219_ChIP-ChIP_H3396_Human1.80537758
21IRF8_21731497_ChIP-ChIP_J774_Mouse1.76232726
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.70100060
23EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67818402
24EGR1_23403033_ChIP-Seq_LIVER_Mouse1.67444860
25VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.67021864
26P300_19829295_ChIP-Seq_ESCs_Human1.64650246
27EWS_26573619_Chip-Seq_HEK293_Human1.64629970
28SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.57118854
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.56748528
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.48663241
31RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.42596381
32MYB_26560356_Chip-Seq_TH2_Human1.41816674
33CBP_20019798_ChIP-Seq_JUKART_Human1.41009885
34IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41009885
35GATA3_26560356_Chip-Seq_TH2_Human1.40992843
36BCAT_22108803_ChIP-Seq_LS180_Human1.39666609
37ESR1_20079471_ChIP-ChIP_T-47D_Human1.38912942
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.38826487
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.37030368
40RUNX_20019798_ChIP-Seq_JUKART_Human1.36723781
41VDR_24787735_ChIP-Seq_THP-1_Human1.35043043
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.33646445
43LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.33493641
44CTBP1_25329375_ChIP-Seq_LNCAP_Human1.31252652
45TP63_19390658_ChIP-ChIP_HaCaT_Human1.29707847
46HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29592733
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.27446502
48TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27446502
49STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24031938
50TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.23918614
51PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23692775
52NANOG_20526341_ChIP-Seq_ESCs_Human1.23422541
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.22116182
54GATA3_21878914_ChIP-Seq_MCF-7_Human1.21495313
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.20864321
56GATA3_27048872_Chip-Seq_THYMUS_Human1.20653307
57MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.20257192
58VDR_23849224_ChIP-Seq_CD4+_Human1.20057990
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.19121571
60ZFP57_27257070_Chip-Seq_ESCs_Mouse1.18378434
61UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17002358
62FUS_26573619_Chip-Seq_HEK293_Human1.13064823
63MYB_26560356_Chip-Seq_TH1_Human1.10506963
64ELK1_19687146_ChIP-ChIP_HELA_Human1.10365650
65GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09827446
66GATA2_21666600_ChIP-Seq_HMVEC_Human1.09221728
67NANOG_19829295_ChIP-Seq_ESCs_Human1.09081873
68SOX2_19829295_ChIP-Seq_ESCs_Human1.09081873
69CDX2_22108803_ChIP-Seq_LS180_Human1.08312069
70SPI1_23547873_ChIP-Seq_NB4_Human1.07328042
71MYC_18940864_ChIP-ChIP_HL60_Human1.06802803
72FOXP3_21729870_ChIP-Seq_TREG_Human1.06000494
73IRF8_27001747_Chip-Seq_BMDM_Mouse1.05465390
74RXR_22108803_ChIP-Seq_LS180_Human1.05225878
75KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02896925
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01411420
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01057834
78AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00953758
79HOXB7_26014856_ChIP-Seq_BT474_Human0.99397134
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.99337113
81AR_21572438_ChIP-Seq_LNCaP_Human0.97475881
82PRDM14_20953172_ChIP-Seq_ESCs_Human0.96018603
83RUNX2_22187159_ChIP-Seq_PCA_Human0.94776360
84SPI1_23127762_ChIP-Seq_K562_Human0.93917523
85FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93811261
86FOXA1_21572438_ChIP-Seq_LNCaP_Human0.92161343
87AR_20517297_ChIP-Seq_VCAP_Human0.91735484
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91459968
89TCF4_22108803_ChIP-Seq_LS180_Human0.91395627
90TCF4_23295773_ChIP-Seq_U87_Human0.90703826
91GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.90217402
92NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89648900
93STAT3_23295773_ChIP-Seq_U87_Human0.89302779
94GATA3_26560356_Chip-Seq_TH1_Human0.89020638
95SMAD4_21741376_ChIP-Seq_EPCs_Human0.88761072
96SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88239888
97SMAD4_21799915_ChIP-Seq_A2780_Human0.88179833
98NCOR_22424771_ChIP-Seq_293T_Human0.86517985
99SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.86272432
100E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.86167408

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008004_abnormal_stomach_pH3.27450540
2MP0002837_dystrophic_cardiac_calcinosis2.90100329
3MP0009278_abnormal_bone_marrow2.83663766
4MP0003136_yellow_coat_color2.76103051
5MP0002138_abnormal_hepatobiliary_system2.73579045
6MP0002132_abnormal_respiratory_system2.71803056
7MP0000465_gastrointestinal_hemorrhage2.48862280
8MP0005464_abnormal_platelet_physiology2.42240190
9MP0008057_abnormal_DNA_replication2.38485036
10MP0003806_abnormal_nucleotide_metabolis2.29001159
11MP0003724_increased_susceptibility_to2.18045899
12MP0005397_hematopoietic_system_phenotyp2.18010621
13MP0001545_abnormal_hematopoietic_system2.18010621
14MP0001835_abnormal_antigen_presentation2.16944220
15MP0002254_reproductive_system_inflammat2.04372923
16MP0008058_abnormal_DNA_repair1.90845285
17MP0002148_abnormal_hypersensitivity_rea1.83101766
18MP0001800_abnormal_humoral_immune1.81448984
19MP0005410_abnormal_fertilization1.77927079
20MP0008877_abnormal_DNA_methylation1.75103349
21MP0002653_abnormal_ependyma_morphology1.73880971
22MP0009697_abnormal_copulation1.71180946
23MP0005646_abnormal_pituitary_gland1.67303300
24MP0003763_abnormal_thymus_physiology1.63432614
25MP0004381_abnormal_hair_follicle1.58815845
26MP0002452_abnormal_antigen_presenting1.55257839
27MP0003195_calcinosis1.54007423
28MP0002420_abnormal_adaptive_immunity1.52163040
29MP0006292_abnormal_olfactory_placode1.50947720
30MP0001819_abnormal_immune_cell1.48924090
31MP0009764_decreased_sensitivity_to1.48582285
32MP0002419_abnormal_innate_immunity1.47878964
33MP0003646_muscle_fatigue1.46228256
34MP0010094_abnormal_chromosome_stability1.45527745
35MP0005167_abnormal_blood-brain_barrier1.44416424
36MP0002723_abnormal_immune_serum1.43883638
37MP0002160_abnormal_reproductive_system1.42602123
38MP0002102_abnormal_ear_morphology1.40098439
39MP0002398_abnormal_bone_marrow1.37597157
40MP0003718_maternal_effect1.35594668
41MP0005075_abnormal_melanosome_morpholog1.35353033
42MP0000685_abnormal_immune_system1.34858230
43MP0005084_abnormal_gallbladder_morpholo1.34653740
44MP0002277_abnormal_respiratory_mucosa1.34564946
45MP0006072_abnormal_retinal_apoptosis1.34249689
46MP0000689_abnormal_spleen_morphology1.32775479
47MP0005387_immune_system_phenotype1.29532356
48MP0001790_abnormal_immune_system1.29532356
49MP0008872_abnormal_physiological_respon1.29524604
50MP0000716_abnormal_immune_system1.29477545
51MP0005000_abnormal_immune_tolerance1.26606721
52MP0005025_abnormal_response_to1.26398104
53MP0002722_abnormal_immune_system1.25627794
54MP0004808_abnormal_hematopoietic_stem1.24657403
55MP0008007_abnormal_cellular_replicative1.24346231
56MP0002876_abnormal_thyroid_physiology1.24254613
57MP0009840_abnormal_foam_cell1.24199466
58MP0002405_respiratory_system_inflammati1.23372658
59MP0005174_abnormal_tail_pigmentation1.16762207
60MP0003890_abnormal_embryonic-extraembry1.15760993
61MP0010386_abnormal_urinary_bladder1.15673352
62MP0005671_abnormal_response_to1.15373042
63MP0000015_abnormal_ear_pigmentation1.15314155
64MP0000703_abnormal_thymus_morphology1.13614271
65MP0004484_altered_response_of1.09329017
66MP0009785_altered_susceptibility_to1.07061718
67MP0001879_abnormal_lymphatic_vessel1.06847589
68MP0002429_abnormal_blood_cell1.06565407
69MP0004142_abnormal_muscle_tone1.02735681
70MP0000230_abnormal_systemic_arterial0.96295248
71MP0005647_abnormal_sex_gland0.95399310
72MP0001845_abnormal_inflammatory_respons0.92565417
73MP0003315_abnormal_perineum_morphology0.92540136
74MP0003828_pulmonary_edema0.91892521
75MP0004084_abnormal_cardiac_muscle0.91658838
76MP0001929_abnormal_gametogenesis0.89883562
77MP0004043_abnormal_pH_regulation0.85936792
78MP0001968_abnormal_touch/_nociception0.85634970
79MP0003787_abnormal_imprinting0.84723389
80MP0010155_abnormal_intestine_physiology0.84327718
81MP0005367_renal/urinary_system_phenotyp0.82360045
82MP0000516_abnormal_urinary_system0.82360045
83MP0002163_abnormal_gland_morphology0.81216047
84MP0003436_decreased_susceptibility_to0.80819537
85MP0006036_abnormal_mitochondrial_physio0.80773006
86MP0005389_reproductive_system_phenotype0.79615015
87MP0005083_abnormal_biliary_tract0.79272845
88MP0005266_abnormal_metabolism0.78576316
89MP0002396_abnormal_hematopoietic_system0.76620186
90MP0006054_spinal_hemorrhage0.75445000
91MP0001501_abnormal_sleep_pattern0.75373286
92MP0010368_abnormal_lymphatic_system0.75051273
93MP0005551_abnormal_eye_electrophysiolog0.74852199
94MP0005253_abnormal_eye_physiology0.73091785
95MP0000569_abnormal_digit_pigmentation0.72788720
96MP0002019_abnormal_tumor_incidence0.71263958
97MP0005377_hearing/vestibular/ear_phenot0.71071088
98MP0003878_abnormal_ear_physiology0.71071088
99MP0003698_abnormal_male_reproductive0.69132530
100MP0008961_abnormal_basal_metabolism0.68922347

Predicted human phenotypes

RankGene SetZ-score
1Eosinophilia (HP:0001880)3.52370371
2Abnormality of the columella (HP:0009929)3.50159140
3Clumsiness (HP:0002312)3.41657086
4Abnormality of B cell number (HP:0010975)3.34883230
5Pancreatic cysts (HP:0001737)3.33315549
6Panhypogammaglobulinemia (HP:0003139)3.22017841
7Thyroiditis (HP:0100646)3.17905298
8Stomatitis (HP:0010280)3.11551341
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.02920545
10B lymphocytopenia (HP:0010976)2.91004052
11Prolonged bleeding time (HP:0003010)2.90859343
12Hematochezia (HP:0002573)2.90040417
13Pancreatic fibrosis (HP:0100732)2.90037853
14Abnormality of eosinophils (HP:0001879)2.87922039
15Granulocytopenia (HP:0001913)2.87046239
16Clubbing of toes (HP:0100760)2.81138009
17Aplastic anemia (HP:0001915)2.80683548
18True hermaphroditism (HP:0010459)2.77301684
19Dyschromatopsia (HP:0007641)2.66380427
20Severe combined immunodeficiency (HP:0004430)2.63196972
21Petechiae (HP:0000967)2.62353529
22Absent rod-and cone-mediated responses on ERG (HP:0007688)2.60092186
23Abnormality of the ileum (HP:0001549)2.57798694
24Abnormality of chromosome stability (HP:0003220)2.56676365
25Acute lymphatic leukemia (HP:0006721)2.55037742
26Abnormality of DNA repair (HP:0003254)2.50558741
27Abnormal rod and cone electroretinograms (HP:0008323)2.48290501
28Meckel diverticulum (HP:0002245)2.46444314
29Leukocytosis (HP:0001974)2.44160956
30Neoplasm of the adrenal cortex (HP:0100641)2.42788116
31Reduced antithrombin III activity (HP:0001976)2.37889615
32Hypoplasia of the thymus (HP:0000778)2.37765913
33Abolished electroretinogram (ERG) (HP:0000550)2.36163652
34Chromsome breakage (HP:0040012)2.36026734
35Median cleft lip (HP:0000161)2.33235453
36Autoimmune hemolytic anemia (HP:0001890)2.32450549
37Chronic hepatic failure (HP:0100626)2.31496039
38Recurrent fungal infections (HP:0002841)2.31278063
39Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.30517726
40Attenuation of retinal blood vessels (HP:0007843)2.29562227
41Absent thumb (HP:0009777)2.28007915
42Decreased central vision (HP:0007663)2.26291140
43Hypoproteinemia (HP:0003075)2.25176581
44Chromosomal breakage induced by crosslinking agents (HP:0003221)2.23036840
45Hyperglycinemia (HP:0002154)2.19480725
46Abnormality of lateral ventricle (HP:0030047)2.17682190
47Anencephaly (HP:0002323)2.15697336
48Colon cancer (HP:0003003)2.14311029
49Stomach cancer (HP:0012126)2.13380950
50Abnormality of the renal cortex (HP:0011035)2.12696579
51Abnormality of the renal medulla (HP:0100957)2.11733400
52Cerebellar dysplasia (HP:0007033)2.11202966
53Autoimmune thrombocytopenia (HP:0001973)2.07529226
54Absent/shortened dynein arms (HP:0200106)2.06371251
55Dynein arm defect of respiratory motile cilia (HP:0012255)2.06371251
56Inability to walk (HP:0002540)2.05664705
57Combined immunodeficiency (HP:0005387)2.04694629
58Abnormality of T cell number (HP:0011839)2.02246982
59Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.01980165
60Abnormality of midbrain morphology (HP:0002418)2.01839028
61Molar tooth sign on MRI (HP:0002419)2.01839028
62Type II lissencephaly (HP:0007260)2.01618757
63Cystic liver disease (HP:0006706)2.00194836
64Increased neuronal autofluorescent lipopigment (HP:0002074)1.96752549
65Nephronophthisis (HP:0000090)1.96335080
66Abnormal protein glycosylation (HP:0012346)1.96277548
67Abnormal glycosylation (HP:0012345)1.96277548
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.96277548
69Abnormal protein N-linked glycosylation (HP:0012347)1.96277548
70Abnormal biliary tract physiology (HP:0012439)1.95479821
71Bile duct proliferation (HP:0001408)1.95479821
72Facial diplegia (HP:0001349)1.94184446
73T lymphocytopenia (HP:0005403)1.93554527
74IgG deficiency (HP:0004315)1.91381289
75Enlarged kidneys (HP:0000105)1.89688386
76Abnormality of the frontal sinuses (HP:0002687)1.89088049
77Elevated erythrocyte sedimentation rate (HP:0003565)1.89081401
78Epistaxis (HP:0000421)1.88988490
79Abnormal delayed hypersensitivity skin test (HP:0002963)1.88180575
80Congenital hepatic fibrosis (HP:0002612)1.87802093
81Tubular atrophy (HP:0000092)1.87632855
82Sloping forehead (HP:0000340)1.86299141
83Prostate neoplasm (HP:0100787)1.85291180
84Abnormality of the prostate (HP:0008775)1.85082519
85Recurrent viral infections (HP:0004429)1.84711284
86Spontaneous hematomas (HP:0007420)1.83310667
87Abnormality of the preputium (HP:0100587)1.81938137
88Methylmalonic aciduria (HP:0012120)1.78082879
89Gonadal dysgenesis (HP:0000133)1.77474971
90Neonatal respiratory distress (HP:0002643)1.76574125
91Recurrent cutaneous fungal infections (HP:0011370)1.76394352
92Chronic mucocutaneous candidiasis (HP:0002728)1.76394352
93Protruding tongue (HP:0010808)1.75583486
94Carpal bone hypoplasia (HP:0001498)1.74341645
95Bone marrow hypocellularity (HP:0005528)1.73371026
96Absent speech (HP:0001344)1.73364368
97Abnormal ciliary motility (HP:0012262)1.72233102
98Myositis (HP:0100614)1.69523979
99Aplasia/Hypoplasia of the tibia (HP:0005772)1.66851811
100Duplicated collecting system (HP:0000081)1.66356830

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.62235275
2PINK14.57398255
3BMPR1B3.50436213
4ZAK3.35927170
5ACVR1B3.09776429
6MARK32.91996099
7NEK22.75211280
8TAOK32.48709795
9NLK2.18039819
10TGFBR12.04617843
11LATS12.02569709
12NUAK11.82362234
13TIE11.75761385
14MAP4K11.68436355
15STK38L1.66676510
16ADRBK21.63839548
17BTK1.54022930
18MELK1.41324538
19TLK11.40959200
20FLT31.39265413
21TEC1.38073113
22CSNK1A1L1.37142511
23PIK3CG1.35313638
24WNK31.34356199
25TXK1.31089770
26GRK11.29275774
27FES1.26581237
28MAP4K21.26344673
29IKBKB1.23167296
30OBSCN1.20551277
31IKBKE1.19183936
32EIF2AK31.11870451
33MAP2K71.10196069
34TAF11.10195541
35TRIM281.08940028
36KIT1.08176048
37VRK11.04909540
38MYLK1.03995134
39SYK1.00080858
40TNK20.98074289
41CSNK1G10.97332793
42CCNB10.96282883
43CSNK1G30.94650149
44VRK20.90351211
45PRKCQ0.89049643
46CDC70.87794347
47CDK30.87758757
48PTK2B0.83657648
49TNIK0.83269029
50CDK120.82151119
51MAP3K10.81737839
52MAP3K130.81255115
53DYRK30.81179422
54IRAK10.79174113
55ZAP700.75971355
56BRD40.75210449
57AKT30.74714446
58RPS6KA50.73193731
59IRAK20.72143503
60MAP3K70.70891285
61GRK60.62120257
62MST40.61697727
63STK380.60432043
64MAPK150.58322323
65GRK50.57968285
66MAPKAPK30.57451890
67CSNK1G20.57405748
68JAK30.57270358
69PIM10.54669798
70FGR0.54531485
71TBK10.53773676
72CHUK0.53056899
73HCK0.51114430
74STK30.50381272
75GRK70.46188672
76SGK20.46128988
77DYRK20.42640599
78ADRBK10.41856801
79MKNK10.41811207
80CSF1R0.40104213
81NME10.39456878
82MKNK20.38743667
83ATR0.38500835
84KDR0.37971998
85LCK0.37462405
86MATK0.36656286
87LYN0.36368027
88BLK0.36229528
89CAMK1D0.35919186
90TRPM70.35586212
91ATM0.35096435
92PLK20.34781167
93EGFR0.33902567
94BMPR20.33338769
95PRKAA20.33195886
96RPS6KA40.33135038
97MAP3K140.32601426
98IRAK40.31233337
99ITK0.31048278
100RIPK40.26804716

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.74460445
2Olfactory transduction_Homo sapiens_hsa047402.74356968
3Fanconi anemia pathway_Homo sapiens_hsa034602.68665505
4Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.64743009
5Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.49603985
6Primary immunodeficiency_Homo sapiens_hsa053402.30527304
7Homologous recombination_Homo sapiens_hsa034402.27730686
8Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.15178687
9Basal transcription factors_Homo sapiens_hsa030222.15122029
10Nitrogen metabolism_Homo sapiens_hsa009101.97523506
11Butanoate metabolism_Homo sapiens_hsa006501.75179277
12Non-homologous end-joining_Homo sapiens_hsa034501.62457793
13Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.61624648
14RNA degradation_Homo sapiens_hsa030181.60394192
15NF-kappa B signaling pathway_Homo sapiens_hsa040641.59790891
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.58529512
17Platelet activation_Homo sapiens_hsa046111.54886628
18Hematopoietic cell lineage_Homo sapiens_hsa046401.51065023
19Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.50207375
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.45474254
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.44912971
22Arachidonic acid metabolism_Homo sapiens_hsa005901.41618588
23Selenocompound metabolism_Homo sapiens_hsa004501.41109675
24Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.40971289
25Intestinal immune network for IgA production_Homo sapiens_hsa046721.37489004
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.33053827
27Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.31074298
28DNA replication_Homo sapiens_hsa030301.27662695
29Asthma_Homo sapiens_hsa053101.24298528
30Systemic lupus erythematosus_Homo sapiens_hsa053221.24061381
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.23538397
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.22385782
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.12074569
34Linoleic acid metabolism_Homo sapiens_hsa005911.09679753
35Mismatch repair_Homo sapiens_hsa034301.09638664
36Chemical carcinogenesis_Homo sapiens_hsa052041.07530136
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04009349
38Propanoate metabolism_Homo sapiens_hsa006401.03995336
39Base excision repair_Homo sapiens_hsa034101.02896840
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00529043
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.00034149
42B cell receptor signaling pathway_Homo sapiens_hsa046620.98854574
43Regulation of autophagy_Homo sapiens_hsa041400.95536098
44Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.95056748
45Legionellosis_Homo sapiens_hsa051340.92744158
46Vascular smooth muscle contraction_Homo sapiens_hsa042700.91016422
47Tryptophan metabolism_Homo sapiens_hsa003800.90266940
48Herpes simplex infection_Homo sapiens_hsa051680.90232577
49Osteoclast differentiation_Homo sapiens_hsa043800.87422501
50Peroxisome_Homo sapiens_hsa041460.86296799
51Allograft rejection_Homo sapiens_hsa053300.80690429
52Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.78887944
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.78838774
54Nucleotide excision repair_Homo sapiens_hsa034200.78596695
55Ether lipid metabolism_Homo sapiens_hsa005650.78464241
56Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78027189
57Other glycan degradation_Homo sapiens_hsa005110.77534566
58Purine metabolism_Homo sapiens_hsa002300.76974238
59Graft-versus-host disease_Homo sapiens_hsa053320.76064898
60RNA polymerase_Homo sapiens_hsa030200.75574056
61Dorso-ventral axis formation_Homo sapiens_hsa043200.74915919
62Glutathione metabolism_Homo sapiens_hsa004800.74869414
63Circadian rhythm_Homo sapiens_hsa047100.73860017
64Toll-like receptor signaling pathway_Homo sapiens_hsa046200.73199234
65beta-Alanine metabolism_Homo sapiens_hsa004100.73013687
66Rheumatoid arthritis_Homo sapiens_hsa053230.73008971
67Tuberculosis_Homo sapiens_hsa051520.70794344
68Autoimmune thyroid disease_Homo sapiens_hsa053200.69264815
69TNF signaling pathway_Homo sapiens_hsa046680.69174973
70T cell receptor signaling pathway_Homo sapiens_hsa046600.68823278
71Calcium signaling pathway_Homo sapiens_hsa040200.68625564
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.64512043
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.61773597
74Measles_Homo sapiens_hsa051620.61492107
75Staphylococcus aureus infection_Homo sapiens_hsa051500.60684605
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.60666263
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59761848
78Sphingolipid metabolism_Homo sapiens_hsa006000.59318609
79Hedgehog signaling pathway_Homo sapiens_hsa043400.59196763
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.58890058
81Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57887313
82ABC transporters_Homo sapiens_hsa020100.57799470
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.57629479
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.57602089
85Taste transduction_Homo sapiens_hsa047420.57259062
86p53 signaling pathway_Homo sapiens_hsa041150.56486392
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.54047857
88Pyrimidine metabolism_Homo sapiens_hsa002400.53572457
89Malaria_Homo sapiens_hsa051440.52166429
90Apoptosis_Homo sapiens_hsa042100.51979687
91Oxytocin signaling pathway_Homo sapiens_hsa049210.51407246
92Hepatitis B_Homo sapiens_hsa051610.50651541
93Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49714533
94Lysosome_Homo sapiens_hsa041420.48995068
95FoxO signaling pathway_Homo sapiens_hsa040680.46017954
96Influenza A_Homo sapiens_hsa051640.44817435
97TGF-beta signaling pathway_Homo sapiens_hsa043500.43731578
98Leishmaniasis_Homo sapiens_hsa051400.41821754
99Ovarian steroidogenesis_Homo sapiens_hsa049130.40311233
100Melanoma_Homo sapiens_hsa052180.40156764

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »