CDC14A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.83773292
2negative regulation of cell killing (GO:0031342)5.83773292
3axonemal dynein complex assembly (GO:0070286)5.09039974
4cilium or flagellum-dependent cell motility (GO:0001539)4.84729816
5positive T cell selection (GO:0043368)4.50744527
6positive regulation of granulocyte differentiation (GO:0030854)4.43014823
7positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.41921814
8response to interleukin-15 (GO:0070672)4.29552574
9sperm motility (GO:0030317)4.25741261
10cilium movement (GO:0003341)4.21366438
11T cell selection (GO:0045058)4.21183918
12cell wall macromolecule metabolic process (GO:0044036)4.20891262
13cell wall macromolecule catabolic process (GO:0016998)4.20891262
14epithelial cilium movement (GO:0003351)4.13652036
15acrosome assembly (GO:0001675)4.08764877
16daunorubicin metabolic process (GO:0044597)4.08519574
17polyketide metabolic process (GO:0030638)4.08519574
18doxorubicin metabolic process (GO:0044598)4.08519574
19motile cilium assembly (GO:0044458)3.98114082
20fusion of sperm to egg plasma membrane (GO:0007342)3.95320795
21cellular response to interleukin-15 (GO:0071350)3.95152110
22glomerular visceral epithelial cell development (GO:0072015)3.92662852
23negative regulation of T cell mediated immunity (GO:0002710)3.80948331
24negative regulation of lymphocyte mediated immunity (GO:0002707)3.75068817
25antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.73682816
26antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.73682816
27glomerular epithelial cell development (GO:0072310)3.72594125
28regulation of regulatory T cell differentiation (GO:0045589)3.70919268
29activated T cell proliferation (GO:0050798)3.67732105
30epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.63387273
31antigen processing and presentation of endogenous antigen (GO:0019883)3.61399201
32multicellular organism reproduction (GO:0032504)3.61288679
33neutrophil activation involved in immune response (GO:0002283)3.59792763
34definitive hemopoiesis (GO:0060216)3.48716150
35regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.46519176
36alpha-beta T cell differentiation (GO:0046632)3.44399025
37sperm-egg recognition (GO:0035036)3.44370512
38B cell receptor signaling pathway (GO:0050853)3.41480678
39antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.40286206
40negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.38265614
41cell-cell recognition (GO:0009988)3.35223200
42mast cell activation (GO:0045576)3.34983570
43histone H3-K36 demethylation (GO:0070544)3.33605867
44acrosome reaction (GO:0007340)3.32429022
45positive regulation of B cell differentiation (GO:0045579)3.30019052
46T cell receptor signaling pathway (GO:0050852)3.24291507
47negative regulation of erythrocyte differentiation (GO:0045647)3.23154830
48positive regulation of interleukin-2 production (GO:0032743)3.23129115
49spermatid development (GO:0007286)3.16745662
50antigen receptor-mediated signaling pathway (GO:0050851)3.15602303
51negative regulation of inclusion body assembly (GO:0090084)3.12742913
52positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.12626904
53regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.12626904
54phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.11794151
55T cell differentiation (GO:0030217)3.11411280
56glomerulus development (GO:0032835)3.11066880
57leukocyte degranulation (GO:0043299)3.10882376
58negative regulation of leukocyte mediated immunity (GO:0002704)3.10758265
59positive regulation of gamma-delta T cell activation (GO:0046645)3.09521256
60reproduction (GO:0000003)3.06116902
61negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.04978977
62negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.04555894
63regulation of interleukin-2 biosynthetic process (GO:0045076)3.03667448
64negative regulation of interleukin-1 beta production (GO:0032691)3.03367463
65negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.02047769
66negative regulation of T-helper cell differentiation (GO:0045623)3.02047769
67regulation of T cell tolerance induction (GO:0002664)2.97605278
68negative regulation of adaptive immune response (GO:0002820)2.96437592
69binding of sperm to zona pellucida (GO:0007339)2.95217413
70G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)2.95167335
71positive regulation of mRNA catabolic process (GO:0061014)2.94770365
72regulation of granulocyte differentiation (GO:0030852)2.94397737
73ventricular system development (GO:0021591)2.94108376
74regulation of isotype switching to IgG isotypes (GO:0048302)2.93887393
75CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.93566397
76T-helper cell differentiation (GO:0042093)2.93566397
77regulation of natural killer cell mediated immunity (GO:0002715)2.92149122
78regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.92149122
79interkinetic nuclear migration (GO:0022027)2.90587589
80positive regulation of T cell differentiation in thymus (GO:0033089)2.89843415
81mitotic sister chromatid cohesion (GO:0007064)2.87475465
82positive regulation by symbiont of host defense response (GO:0052509)2.86515080
83modulation by symbiont of host defense response (GO:0052031)2.86515080
84modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.86515080
85modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.86515080
86positive regulation by organism of defense response of other organism involved in symbiotic interact2.86515080
87modulation by symbiont of host immune response (GO:0052553)2.86515080
88mast cell activation involved in immune response (GO:0002279)2.86417586
89mast cell degranulation (GO:0043303)2.86417586
90NIK/NF-kappaB signaling (GO:0038061)2.85740445
91plasma membrane fusion (GO:0045026)2.84891813
92tolerance induction (GO:0002507)2.83917761
93hepatocyte apoptotic process (GO:0097284)2.81211657
94T cell homeostasis (GO:0043029)2.76792871
95mucosal-associated lymphoid tissue development (GO:0048537)2.76291830
96Peyers patch development (GO:0048541)2.76291830
97regulation of B cell receptor signaling pathway (GO:0050855)2.75178640
98positive thymic T cell selection (GO:0045059)2.74562111
99regulation of fibroblast apoptotic process (GO:2000269)2.73806642
100nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423)2.73623853
101granulocyte activation (GO:0036230)2.71070765
102positive regulation of isotype switching (GO:0045830)2.68778825
103sperm capacitation (GO:0048240)2.68501084
104interferon-gamma production (GO:0032609)2.67881228
105regulation of alpha-beta T cell activation (GO:0046634)2.67464697
106glomerular basement membrane development (GO:0032836)2.64565640
107regulation of activation of Janus kinase activity (GO:0010533)2.60298286
108leukocyte aggregation (GO:0070486)2.57593295
109positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.56737360
110alpha-beta T cell differentiation involved in immune response (GO:0002293)2.54176879
111alpha-beta T cell activation involved in immune response (GO:0002287)2.54176879
112T cell differentiation involved in immune response (GO:0002292)2.54176879
113regulation of cilium movement (GO:0003352)2.53664969
114regulation of interleukin-12 biosynthetic process (GO:0045075)2.51742854
115left/right axis specification (GO:0070986)2.51503180
116single fertilization (GO:0007338)2.51313716
117aminoglycoside antibiotic metabolic process (GO:0030647)2.51302718
118myeloid dendritic cell activation (GO:0001773)2.46751287
119regulation of gamma-delta T cell activation (GO:0046643)2.44352408
120negative thymic T cell selection (GO:0045060)2.43065246
121regulation of gamma-delta T cell differentiation (GO:0045586)2.43036974
122negative T cell selection (GO:0043383)2.39189219
123response to muramyl dipeptide (GO:0032495)2.37350807
124regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.36805547
125natural killer cell mediated cytotoxicity (GO:0042267)2.35157649
126natural killer cell mediated immunity (GO:0002228)2.35157649
127regulation of tolerance induction (GO:0002643)2.34673668
128neutrophil activation (GO:0042119)2.31861507
129negative regulation of phagocytosis (GO:0050765)2.31837280
130regulation of necroptotic process (GO:0060544)2.31329077
131CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.29005255
132male meiosis (GO:0007140)2.28464869
133regulation of alpha-beta T cell proliferation (GO:0046640)2.27291438
134regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.25859701
135monoubiquitinated protein deubiquitination (GO:0035520)2.25349204
136positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.24929066
137thymic T cell selection (GO:0045061)2.23861147
138T-helper 1 type immune response (GO:0042088)2.23381316
139cellular extravasation (GO:0045123)2.20411868
140myeloid dendritic cell differentiation (GO:0043011)2.20103674
141megakaryocyte development (GO:0035855)2.18221263
142regulation of B cell differentiation (GO:0045577)2.17486137
143centriole assembly (GO:0098534)2.17406883
144regulation of RIG-I signaling pathway (GO:0039535)2.17035271
145positive regulation of alpha-beta T cell proliferation (GO:0046641)2.17002925
146spermatid nucleus differentiation (GO:0007289)2.16812350
147T cell migration (GO:0072678)2.15983898
148negative regulation of necroptotic process (GO:0060546)2.15399860
149alpha-beta T cell activation (GO:0046631)2.15316113
150regulation of T cell receptor signaling pathway (GO:0050856)2.14887488
151dendritic cell chemotaxis (GO:0002407)2.14429258
152positive regulation of tolerance induction (GO:0002645)2.13856805
153spermatogenesis (GO:0007283)2.13661194
154dendritic cell migration (GO:0036336)2.13608432
155male gamete generation (GO:0048232)2.12700186
156Arp2/3 complex-mediated actin nucleation (GO:0034314)2.12483797
157energy homeostasis (GO:0097009)2.11826794
158tyrosine phosphorylation of STAT protein (GO:0007260)2.11755706
159RNA destabilization (GO:0050779)2.11745739
160embryonic camera-type eye morphogenesis (GO:0048596)2.10891767
161CD4-positive, alpha-beta T cell activation (GO:0035710)2.10537449
162positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.10418982
163T cell activation involved in immune response (GO:0002286)2.09676654

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.18777366
2* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.96178166
3SCL_19346495_ChIP-Seq_HPC-7_Human3.78795648
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.74891425
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.54468023
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.17776435
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.06745962
8STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.97048444
9E2F7_22180533_ChIP-Seq_HELA_Human2.85652641
10GATA1_22025678_ChIP-Seq_K562_Human2.72989218
11MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.67125131
12IRF8_27001747_Chip-Seq_BMDM_Mouse2.54436965
13* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.42430023
14RUNX_20019798_ChIP-Seq_JUKART_Human2.40724864
15* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.38111880
16* MYB_26560356_Chip-Seq_TH2_Human2.35187414
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.35106859
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.19944740
19IRF8_21731497_ChIP-ChIP_J774_Mouse2.19501199
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.19404769
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.12597450
22STAT4_19710469_ChIP-ChIP_TH1__Mouse2.07353844
23BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.04365213
24EGR1_19374776_ChIP-ChIP_THP-1_Human2.02991136
25RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.91353166
26* MYB_26560356_Chip-Seq_TH1_Human1.91117395
27SALL1_21062744_ChIP-ChIP_HESCs_Human1.91094827
28SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.84938522
29RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.84422840
30NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81730400
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.78085525
32* MAF_26560356_Chip-Seq_TH1_Human1.69990689
33* SPI1_23547873_ChIP-Seq_NB4_Human1.64021288
34PCGF2_27294783_Chip-Seq_ESCs_Mouse1.63625129
35PCGF2_27294783_Chip-Seq_NPCs_Mouse1.61636451
36LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.58226388
37* MAF_26560356_Chip-Seq_TH2_Human1.58214029
38VDR_24787735_ChIP-Seq_THP-1_Human1.57634547
39LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.55514316
40TCF7_22412390_ChIP-Seq_EML_Mouse1.53970594
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.53358158
42VDR_24763502_ChIP-Seq_THP-1_Human1.52529562
43KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.51004440
44KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.51004440
45KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.51004440
46* RUNX1_22412390_ChIP-Seq_EML_Mouse1.50912294
47SMAD_19615063_ChIP-ChIP_OVARY_Human1.45763487
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.45049223
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.42632815
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.41745564
51GATA3_27048872_Chip-Seq_THYMUS_Human1.40413232
52* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.39101328
53MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.38727594
54KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.37552095
55Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.32824659
56PU_27001747_Chip-Seq_BMDM_Mouse1.31982762
57GATA1_19941826_ChIP-Seq_K562_Human1.30635700
58* UTX_26944678_Chip-Seq_JUKART_Human1.29637088
59GATA2_21666600_ChIP-Seq_HMVEC_Human1.28301654
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28033870
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.27875249
62* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.25420557
63GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.25413833
64SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.24208611
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.24174525
66RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.23595432
67VDR_23849224_ChIP-Seq_CD4+_Human1.23118117
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18976619
69NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.18682693
70* E2F4_17652178_ChIP-ChIP_JURKAT_Human1.16301622
71STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.15542710
72VDR_21846776_ChIP-Seq_THP-1_Human1.15539633
73* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15197216
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14009800
75FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.13574308
76RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12295982
77TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.12168093
78STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11682390
79ELF1_17652178_ChIP-ChIP_JURKAT_Human1.11336356
80GATA2_22383799_ChIP-Seq_G1ME_Mouse1.11226854
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.08614537
82CIITA_25753668_ChIP-Seq_RAJI_Human1.06952158
83EZH2_27294783_Chip-Seq_NPCs_Mouse1.06527045
84* SPI1_23127762_ChIP-Seq_K562_Human1.05212865
85MYC_22102868_ChIP-Seq_BL_Human1.03987972
86VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.02863297
87FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.02622777
88SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.02540103
89TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02428780
90FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.02074026
91PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98927417
92TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.98381032
93HOXB4_20404135_ChIP-ChIP_EML_Mouse0.98314270
94EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.98230973
95FOXO3_23340844_ChIP-Seq_DLD1_Human0.97546274
96SMRT_27268052_Chip-Seq_Bcells_Human0.97003466
97GATA3_26560356_Chip-Seq_TH2_Human0.96519963
98STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95246187
99GATA3_26560356_Chip-Seq_TH1_Human0.93479120
100NFIB_24661679_ChIP-Seq_LUNG_Mouse0.92198255
101CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.92153523
102TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.88851209
103CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88795785
104* OCT4_18555785_Chip-Seq_ESCs_Mouse0.88713591
105NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87464156
106IRF1_19129219_ChIP-ChIP_H3396_Human0.87217981
107* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.86822858
108POU3F2_20337985_ChIP-ChIP_501MEL_Human0.86286926
109FOXP3_21729870_ChIP-Seq_TREG_Human0.85904312
110FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.85726051
111* GATA2_19941826_ChIP-Seq_K562_Human0.85680141
112* KDM2B_26808549_Chip-Seq_JURKAT_Human0.85672685
113* KDM2B_26808549_Chip-Seq_DND41_Human0.84506077
114STAT1_17558387_ChIP-Seq_HELA_Human0.84323733
115NCOR1_26117541_ChIP-Seq_K562_Human0.84272349
116* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.84162116
117VDR_22108803_ChIP-Seq_LS180_Human0.82752424
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82280804
119GATA1_22383799_ChIP-Seq_G1ME_Mouse0.81381066
120GATA1_26923725_Chip-Seq_HPCs_Mouse0.81238546
121NANOG_18555785_Chip-Seq_ESCs_Mouse0.80821038
122* TCF4_18268006_ChIP-ChIP_LS174T_Human0.79049631
123E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.78113136
124WDR5_24793694_ChIP-Seq_LNCAP_Human0.77961303
125TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.77673798
126SUZ12_18555785_Chip-Seq_ESCs_Mouse0.77140499
127CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.77133911
128VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.76911352
129SALL4_22934838_ChIP-ChIP_CD34+_Human0.76652396
130CDX2_19796622_ChIP-Seq_MESCs_Mouse0.76520591
131FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76456721
132CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.75894591
133OCT4_21477851_ChIP-Seq_ESCs_Mouse0.75395466
134GATA1_19941827_ChIP-Seq_MEL86_Mouse0.75093791

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization3.44287486
2MP0001835_abnormal_antigen_presentation2.93936060
3MP0000685_abnormal_immune_system2.62973609
4MP0005671_abnormal_response_to2.31859134
5MP0002166_altered_tumor_susceptibility2.27770009
6MP0003763_abnormal_thymus_physiology2.27432226
7MP0003724_increased_susceptibility_to2.17646313
8MP0002396_abnormal_hematopoietic_system2.13375483
9MP0001873_stomach_inflammation2.09248369
10MP0009785_altered_susceptibility_to2.05825541
11MP0004808_abnormal_hematopoietic_stem2.05657575
12MP0001790_abnormal_immune_system2.04046645
13MP0005387_immune_system_phenotype2.04046645
14MP0002405_respiratory_system_inflammati1.97746958
15MP0001800_abnormal_humoral_immune1.97585157
16MP0001879_abnormal_lymphatic_vessel1.93969992
17MP0002006_tumorigenesis1.92374115
18MP0002452_abnormal_antigen_presenting1.87721939
19MP0001545_abnormal_hematopoietic_system1.86677350
20MP0005397_hematopoietic_system_phenotyp1.86677350
21MP0003656_abnormal_erythrocyte_physiolo1.78507495
22MP0002723_abnormal_immune_serum1.77562880
23MP0008057_abnormal_DNA_replication1.77441969
24MP0002420_abnormal_adaptive_immunity1.77181051
25MP0001819_abnormal_immune_cell1.76473559
26MP0010368_abnormal_lymphatic_system1.74236019
27MP0005000_abnormal_immune_tolerance1.72623491
28MP0002132_abnormal_respiratory_system1.71767105
29MP0002398_abnormal_bone_marrow1.68964304
30MP0002148_abnormal_hypersensitivity_rea1.68753810
31MP0002163_abnormal_gland_morphology1.62535414
32MP0005025_abnormal_response_to1.61631567
33MP0002009_preneoplasia1.58964099
34MP0009278_abnormal_bone_marrow1.57800932
35MP0003300_gastrointestinal_ulcer1.57070040
36MP0001533_abnormal_skeleton_physiology1.56533655
37MP0002419_abnormal_innate_immunity1.54579371
38MP0005377_hearing/vestibular/ear_phenot1.53719142
39MP0003878_abnormal_ear_physiology1.53719142
40MP0000716_abnormal_immune_system1.47751220
41MP0000465_gastrointestinal_hemorrhage1.43639399
42MP0002277_abnormal_respiratory_mucosa1.39111826
43MP0010155_abnormal_intestine_physiology1.38965421
44MP0000490_abnormal_crypts_of1.36760364
45MP0009764_decreased_sensitivity_to1.36231359
46MP0005310_abnormal_salivary_gland1.35257257
47MP0005174_abnormal_tail_pigmentation1.35188488
48MP0009697_abnormal_copulation1.34881528
49MP0001929_abnormal_gametogenesis1.34662796
50MP0003943_abnormal_hepatobiliary_system1.32943249
51MP0002722_abnormal_immune_system1.32631651
52MP0003436_decreased_susceptibility_to1.32227935
53MP0000703_abnormal_thymus_morphology1.31477790
54MP0005075_abnormal_melanosome_morpholog1.29544317
55MP0004381_abnormal_hair_follicle1.27954139
56MP0000689_abnormal_spleen_morphology1.27282334
57MP0002429_abnormal_blood_cell1.24852712
58MP0008007_abnormal_cellular_replicative1.24752723
59MP0003698_abnormal_male_reproductive1.24027993
60MP0008260_abnormal_autophagy1.23750266
61MP0004043_abnormal_pH_regulation1.22239243
62MP0001853_heart_inflammation1.17670865
63MP0005464_abnormal_platelet_physiology1.16437030
64MP0003866_abnormal_defecation1.15394486
65MP0004883_abnormal_blood_vessel1.12436815
66MP0003786_premature_aging1.12359153
67MP0003303_peritoneal_inflammation1.11413182
68MP0008058_abnormal_DNA_repair1.11367941
69MP0004264_abnormal_extraembryonic_tissu1.09663180
70MP0002138_abnormal_hepatobiliary_system1.09359812
71MP0002928_abnormal_bile_duct1.08422369
72MP0001845_abnormal_inflammatory_respons1.08414418
73MP0000015_abnormal_ear_pigmentation1.08322714
74MP0000566_synostosis1.08297182
75MP0008004_abnormal_stomach_pH1.08179281
76MP0004947_skin_inflammation1.06752531
77MP0006082_CNS_inflammation1.06608986
78MP0010094_abnormal_chromosome_stability1.05649748
79MP0010352_gastrointestinal_tract_polyps1.04378505
80MP0002998_abnormal_bone_remodeling1.04225235
81MP0001188_hyperpigmentation1.03436203
82MP0002933_joint_inflammation1.02681043
83MP0003828_pulmonary_edema1.02177788
84MP0003077_abnormal_cell_cycle1.01471401
85MP0005451_abnormal_body_composition0.99723815
86MP0009379_abnormal_foot_pigmentation0.99597275
87MP0008961_abnormal_basal_metabolism0.99151815
88MP0008469_abnormal_protein_level0.95801908
89MP0000858_altered_metastatic_potential0.93074883
90MP0008995_early_reproductive_senescence0.92525432
91MP0002095_abnormal_skin_pigmentation0.92383333
92MP0002210_abnormal_sex_determination0.87895134
93MP0003448_altered_tumor_morphology0.85506711
94MP0009333_abnormal_splenocyte_physiolog0.84852752
95MP0001851_eye_inflammation0.81321104
96MP0005367_renal/urinary_system_phenotyp0.81164930
97MP0000516_abnormal_urinary_system0.81164930
98MP0005379_endocrine/exocrine_gland_phen0.80887223
99MP0000470_abnormal_stomach_morphology0.80429020
100MP0003183_abnormal_peptide_metabolism0.79872599
101MP0001293_anophthalmia0.79482775
102MP0001919_abnormal_reproductive_system0.77429622
103MP0003566_abnormal_cell_adhesion0.76547460
104MP0000569_abnormal_digit_pigmentation0.76449809
105MP0000733_abnormal_muscle_development0.75583838
106MP0008877_abnormal_DNA_methylation0.74803653
107MP0006054_spinal_hemorrhage0.74797509
108MP0003111_abnormal_nucleus_morphology0.74438849
109MP0010234_abnormal_vibrissa_follicle0.74101946
110MP0001346_abnormal_lacrimal_gland0.73004713
111MP0003172_abnormal_lysosome_physiology0.72264500
112MP0001145_abnormal_male_reproductive0.70784251
113MP0002019_abnormal_tumor_incidence0.70524281
114MP0000383_abnormal_hair_follicle0.69405105
115MP0000613_abnormal_salivary_gland0.68283071
116MP0001663_abnormal_digestive_system0.68277788
117MP0000313_abnormal_cell_death0.67705042
118MP0003795_abnormal_bone_structure0.67360015
119MP0000767_abnormal_smooth_muscle0.67085099
120MP0002877_abnormal_melanocyte_morpholog0.67080287
121MP0003693_abnormal_embryo_hatching0.66826995
122MP0002136_abnormal_kidney_physiology0.66025494
123MP0002925_abnormal_cardiovascular_devel0.65983519
124MP0009765_abnormal_xenobiotic_induced0.65735797
125MP0009763_increased_sensitivity_to0.63783172
126MP0005164_abnormal_response_to0.63211861
127MP0000249_abnormal_blood_vessel0.59802897
128MP0004484_altered_response_of0.59094210
129MP0004130_abnormal_muscle_cell0.58450905
130MP0005390_skeleton_phenotype0.56264714
131MP0003787_abnormal_imprinting0.54472158
132MP0010307_abnormal_tumor_latency0.53912108
133MP0005376_homeostasis/metabolism_phenot0.50714819

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)6.26389718
2Absent/shortened dynein arms (HP:0200106)5.79109180
3Dynein arm defect of respiratory motile cilia (HP:0012255)5.79109180
4T lymphocytopenia (HP:0005403)5.38150822
5Abnormal respiratory motile cilium physiology (HP:0012261)5.15554369
6Abnormal respiratory epithelium morphology (HP:0012253)4.72320711
7Abnormal respiratory motile cilium morphology (HP:0005938)4.72320711
8Rhinitis (HP:0012384)4.69649625
9Stomatitis (HP:0010280)4.68722885
10Abnormal ciliary motility (HP:0012262)4.62490898
11Nasal polyposis (HP:0100582)4.25227573
12Abnormality of the nasal mucosa (HP:0000433)4.00596591
13Stomach cancer (HP:0012126)3.95994990
14Chronic bronchitis (HP:0004469)3.84954322
15Bronchiectasis (HP:0002110)3.76047972
16Chronic otitis media (HP:0000389)3.63980631
17Gastrointestinal infarctions (HP:0005244)3.52532042
18Leukocytosis (HP:0001974)3.51492233
19IgG deficiency (HP:0004315)3.50897477
20Bronchitis (HP:0012387)3.39406375
21Abnormality of T cell physiology (HP:0011840)3.35122725
22Granulocytopenia (HP:0001913)3.31248946
23Pustule (HP:0200039)3.26519649
24Eosinophilia (HP:0001880)3.23669806
25Abnormality of B cell number (HP:0010975)3.21748373
26Recurrent bronchitis (HP:0002837)3.09041077
27Encephalitis (HP:0002383)3.08598072
28Recurrent sinusitis (HP:0011108)3.07876378
29Combined immunodeficiency (HP:0005387)3.05958763
30Optic neuritis (HP:0100653)3.04466735
31Retrobulbar optic neuritis (HP:0100654)3.04466735
32Abnormality of the fingertips (HP:0001211)3.01191784
33Papilledema (HP:0001085)2.89900675
34Myositis (HP:0100614)2.88956929
35Chronic sinusitis (HP:0011109)2.79009863
36Orchitis (HP:0100796)2.74436631
37IgM deficiency (HP:0002850)2.72668753
38B lymphocytopenia (HP:0010976)2.70255862
39Neoplasm of the tracheobronchial system (HP:0100552)2.64073002
40Increased IgM level (HP:0003496)2.61618861
41Recurrent abscess formation (HP:0002722)2.60893483
42Recurrent skin infections (HP:0001581)2.58070440
43Alveolar cell carcinoma (HP:0006519)2.51462231
44Chest pain (HP:0100749)2.51352764
45Hypoplasia of the thymus (HP:0000778)2.49402688
46Recurrent fungal infections (HP:0002841)2.47684992
47Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.44161549
48Thyroiditis (HP:0100646)2.34939227
49Epistaxis (HP:0000421)2.34870662
50Basal cell carcinoma (HP:0002671)2.33988613
51Acute hepatic failure (HP:0006554)2.32716708
52Abnormality of the prostate (HP:0008775)2.30487704
53Acute myeloid leukemia (HP:0004808)2.28583401
54Joint swelling (HP:0001386)2.26521171
55True hermaphroditism (HP:0010459)2.25404990
56Nephronophthisis (HP:0000090)2.21986624
57Mediastinal lymphadenopathy (HP:0100721)2.20121280
58Gingival bleeding (HP:0000225)2.19719952
59Recurrent otitis media (HP:0000403)2.19237208
60Prostate neoplasm (HP:0100787)2.18149091
61Eczematoid dermatitis (HP:0000976)2.17273037
62Hypoalbuminemia (HP:0003073)2.15751873
63Abnormal albumin level (HP:0012116)2.15751873
64Aplasia/Hypoplasia of the thymus (HP:0010515)2.15451053
65Abnormality of macrophages (HP:0004311)2.14570006
66Pulmonary embolism (HP:0002204)2.11412992
67Abnormality of the renal medulla (HP:0100957)2.08045532
68Conjunctival telangiectasia (HP:0000524)2.07814176
69Recurrent viral infections (HP:0004429)2.07255036
70Poikilocytosis (HP:0004447)2.05893148
71Spontaneous hematomas (HP:0007420)2.05841051
72Lymphoma (HP:0002665)2.05801027
73Chronic obstructive pulmonary disease (HP:0006510)2.05126263
74Obstructive lung disease (HP:0006536)2.05126263
75Amaurosis fugax (HP:0100576)2.05013722
76Arterial thrombosis (HP:0004420)2.02457197
77Verrucae (HP:0200043)2.02270867
78Papilloma (HP:0012740)2.02270867
79Tubular atrophy (HP:0000092)2.02257925
80Tubulointerstitial nephritis (HP:0001970)2.01333832
81Chronic diarrhea (HP:0002028)2.00378422
82Abnormality of the columella (HP:0009929)2.00252018
83Hematochezia (HP:0002573)2.00073736
84Recurrent bacterial skin infections (HP:0005406)1.97704088
85Depressed nasal tip (HP:0000437)1.97391769
86Abnormal delayed hypersensitivity skin test (HP:0002963)1.94846293
87Infertility (HP:0000789)1.94295160
88Meningitis (HP:0001287)1.94187219
89Vasculitis (HP:0002633)1.93440603
90Inflammation of the large intestine (HP:0002037)1.92532922
91Recurrent gram-negative bacterial infections (HP:0005420)1.91401886
92Pancreatic fibrosis (HP:0100732)1.89079860
93Male infertility (HP:0003251)1.88418595
94Chronic mucocutaneous candidiasis (HP:0002728)1.85879857
95Recurrent cutaneous fungal infections (HP:0011370)1.85879857
96Rectal prolapse (HP:0002035)1.85337605
97Median cleft lip (HP:0000161)1.83211535
98Abnormality of chloride homeostasis (HP:0011422)1.83123032
99Autoimmune hemolytic anemia (HP:0001890)1.82713552
100Keratoconjunctivitis sicca (HP:0001097)1.82680002
101Thrombocytosis (HP:0001894)1.82461179
102Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.80806015
103Abnormal spermatogenesis (HP:0008669)1.80527900
104Abnormality of midbrain morphology (HP:0002418)1.80417074
105Molar tooth sign on MRI (HP:0002419)1.80417074
106Gastrointestinal inflammation (HP:0004386)1.78561382
107Autoimmune thrombocytopenia (HP:0001973)1.78192837
108Agammaglobulinemia (HP:0004432)1.77517183
109Stage 5 chronic kidney disease (HP:0003774)1.76524312
110Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.76154484
111Prolonged bleeding time (HP:0003010)1.72924784
112Colitis (HP:0002583)1.71955693
113Elevated erythrocyte sedimentation rate (HP:0003565)1.71470917
114Midline defect of the nose (HP:0004122)1.70048836
115Keratoconjunctivitis (HP:0001096)1.69374464
116Portal hypertension (HP:0001409)1.67527330
117Mesangial abnormality (HP:0001966)1.67494314
118Chronic hepatic failure (HP:0100626)1.67469869
119Abnormality of the frontal sinuses (HP:0002687)1.66640800
120Persistence of primary teeth (HP:0006335)1.66030325
121Blepharitis (HP:0000498)1.65799422
122IgA deficiency (HP:0002720)1.64191066
123Cellulitis (HP:0100658)1.63925226
124Hyperkalemia (HP:0002153)1.63914211
125Abnormality of the hepatic vasculature (HP:0006707)1.63561572
126Ectopic kidney (HP:0000086)1.62417000
127Abnormality of T cell number (HP:0011839)1.60286121
128Panhypogammaglobulinemia (HP:0003139)1.59972777
129Hemoptysis (HP:0002105)1.59699241
130Abnormality of cells of the lymphoid lineage (HP:0012140)1.59576036
131Optic nerve coloboma (HP:0000588)1.59089973
132Petechiae (HP:0000967)1.58689006
133Pulmonary infiltrates (HP:0002113)1.58269138
134Lymphopenia (HP:0001888)1.57701343
135Abnormality of eosinophils (HP:0001879)1.55695509
136Glomerulopathy (HP:0100820)1.54213530
137Severe combined immunodeficiency (HP:0004430)1.54020372
138Cystic liver disease (HP:0006706)1.52356655
139Abnormality of T cells (HP:0002843)1.51926793

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TAOK34.13120343
2MAP4K13.32518840
3RIPK43.11203308
4TXK2.92567636
5MAPK152.66349246
6GRK62.48587950
7MAP3K142.36812890
8TIE12.36781953
9TEC2.30412378
10IRAK42.27082133
11MAP3K132.25138574
12STK101.99574798
13FRK1.91616278
14BRD41.91032462
15PRPF4B1.88709285
16KIT1.77969195
17CAMKK21.75774066
18JAK31.75078798
19IKBKE1.68895594
20BTK1.68780805
21IRAK31.64968301
22NEK21.55364051
23TBK11.55210994
24PASK1.53964179
25FGFR31.49609158
26SIK31.43894679
27KDR1.42620286
28FES1.40587505
29TGFBR21.39820367
30TYK21.37168820
31ICK1.36851402
32MARK31.36732127
33PLK41.33410380
34IKBKB1.31445973
35MST41.31199570
36CHUK1.30300815
37NLK1.30187525
38RPS6KA41.28739681
39TESK11.27800370
40LMTK21.27695461
41STK31.26922699
42PIK3CG1.25338940
43ITK1.22213652
44NEK91.17254463
45DYRK31.17142788
46PAK41.16502948
47LATS11.16262314
48ZAP701.16143834
49NUAK11.15477823
50TGFBR11.14505054
51IRAK11.12507342
52BRSK21.11335371
53PIM11.10492782
54EPHB11.07255115
55JAK11.03827523
56STK391.02276651
57JAK21.00536909
58BLK0.99278867
59CSK0.98259373
60BMPR20.97306678
61CDK120.97265561
62CSF1R0.93457457
63VRK10.93240032
64MAP4K20.92452632
65PRKG20.91333614
66ACVR1B0.90999312
67EPHB20.90443298
68MAP2K20.89273826
69EEF2K0.88727361
70MAP3K70.87743542
71CAMKK10.79577656
72ATR0.78494085
73MATK0.76836330
74AKT30.76436077
75DYRK1B0.76355342
76LCK0.75662107
77MKNK20.75191502
78GRK10.75165985
79CDK90.71382521
80PDK40.70648076
81PDK30.70648076
82LYN0.67536477
83MELK0.67345353
84FGR0.64435347
85CAMK1D0.63664385
86LRRK20.63265723
87PDK20.63251097
88PRKCQ0.61949701
89TRPM70.61801111
90PTK2B0.61157618
91MAP3K20.59549194
92CDK70.59285760
93SYK0.57912593
94HCK0.57311319
95CAMK1G0.57277504
96SGK20.57108431
97CDK60.57045088
98RIPK10.56973646
99CLK10.56571045
100RPS6KA50.56199986
101CDK80.56029906
102CDK40.55217100
103CDK30.54133876
104MUSK0.54116332
105ZAK0.54082822
106SIK20.53193158
107HIPK20.53116539
108YES10.52931573
109SIK10.52562309
110DMPK0.52309121
111MKNK10.52255615
112BMPR1B0.52166585
113TNIK0.52110732
114RAF10.51271451
115MAP3K100.51197840
116STK40.49720533
117MAP3K60.49633700
118CDC70.49399262
119TAOK10.49163509
120STK240.49100308
121WNK40.47660197
122MAP3K10.46552467
123RPS6KB20.46364987
124PDK10.45739534
125IRAK20.45075149
126MAP2K30.45033448
127PTK60.44167656
128TNK20.43145383
129MAPK70.42994099
130NEK60.42692638
131FGFR40.42579092
132MAPKAPK50.42220539
133MARK20.41220107
134WNK10.39317348
135SGK30.37093062
136RET0.34537859
137KSR20.32905515
138STK38L0.32743331
139EIF2AK20.32734364
140STK110.32247464
141EGFR0.31314463
142MAPK110.30615735
143MAP3K50.29758395

Predicted pathways (KEGG)

RankGene SetZ-score
1Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.34651063
2Primary immunodeficiency_Homo sapiens_hsa053402.25794203
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.23818980
4Leishmaniasis_Homo sapiens_hsa051402.00623031
5Measles_Homo sapiens_hsa051621.99372926
6B cell receptor signaling pathway_Homo sapiens_hsa046621.92099413
7Intestinal immune network for IgA production_Homo sapiens_hsa046721.89342622
8Non-small cell lung cancer_Homo sapiens_hsa052231.80013228
9Antigen processing and presentation_Homo sapiens_hsa046121.78939865
10Osteoclast differentiation_Homo sapiens_hsa043801.68627622
11Herpes simplex infection_Homo sapiens_hsa051681.68056627
12Hematopoietic cell lineage_Homo sapiens_hsa046401.67842696
13Fanconi anemia pathway_Homo sapiens_hsa034601.65871629
14Transcriptional misregulation in cancer_Homo sapiens_hsa052021.59148872
15Jak-STAT signaling pathway_Homo sapiens_hsa046301.57780970
16Toxoplasmosis_Homo sapiens_hsa051451.55851693
17Allograft rejection_Homo sapiens_hsa053301.54423704
18T cell receptor signaling pathway_Homo sapiens_hsa046601.53021018
19Toll-like receptor signaling pathway_Homo sapiens_hsa046201.50879324
20TNF signaling pathway_Homo sapiens_hsa046681.49134532
21NOD-like receptor signaling pathway_Homo sapiens_hsa046211.46790137
22Leukocyte transendothelial migration_Homo sapiens_hsa046701.43536610
23Graft-versus-host disease_Homo sapiens_hsa053321.41658753
24Small cell lung cancer_Homo sapiens_hsa052221.39420262
25Influenza A_Homo sapiens_hsa051641.39130270
26Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.34823406
27Homologous recombination_Homo sapiens_hsa034401.33663874
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.26545521
29SNARE interactions in vesicular transport_Homo sapiens_hsa041301.21598921
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21434226
31Legionellosis_Homo sapiens_hsa051341.21020715
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.19041438
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.17991002
34Type I diabetes mellitus_Homo sapiens_hsa049401.17780138
35AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.15490274
36Apoptosis_Homo sapiens_hsa042101.12021012
37Acute myeloid leukemia_Homo sapiens_hsa052211.11754431
38Base excision repair_Homo sapiens_hsa034101.11704702
39Hepatitis B_Homo sapiens_hsa051611.11116930
40DNA replication_Homo sapiens_hsa030301.09059778
41Thyroid cancer_Homo sapiens_hsa052161.07458136
42Basal transcription factors_Homo sapiens_hsa030221.05941453
43Notch signaling pathway_Homo sapiens_hsa043301.05812120
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05632413
45Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.05224217
46Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.04533996
47mTOR signaling pathway_Homo sapiens_hsa041501.03697047
48HTLV-I infection_Homo sapiens_hsa051661.01887149
49Chronic myeloid leukemia_Homo sapiens_hsa052201.00292555
50Viral myocarditis_Homo sapiens_hsa054160.99926872
51Salmonella infection_Homo sapiens_hsa051320.99103784
52Chemokine signaling pathway_Homo sapiens_hsa040620.98329885
53Autoimmune thyroid disease_Homo sapiens_hsa053200.96981020
54Platelet activation_Homo sapiens_hsa046110.96086939
55Pancreatic cancer_Homo sapiens_hsa052120.95822185
56p53 signaling pathway_Homo sapiens_hsa041150.95779489
57Adherens junction_Homo sapiens_hsa045200.94505464
58* Cell cycle_Homo sapiens_hsa041100.92526569
59Pertussis_Homo sapiens_hsa051330.92280271
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91899298
61African trypanosomiasis_Homo sapiens_hsa051430.91568451
62Shigellosis_Homo sapiens_hsa051310.90893073
63Viral carcinogenesis_Homo sapiens_hsa052030.89354486
64Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.89264175
65Malaria_Homo sapiens_hsa051440.88230416
66Staphylococcus aureus infection_Homo sapiens_hsa051500.87550177
67RNA degradation_Homo sapiens_hsa030180.86070160
68Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.85234003
69Regulation of autophagy_Homo sapiens_hsa041400.84459618
70MicroRNAs in cancer_Homo sapiens_hsa052060.81987751
71Renin-angiotensin system_Homo sapiens_hsa046140.80915008
72Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.80477229
73Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80212026
74Non-homologous end-joining_Homo sapiens_hsa034500.78573785
75Choline metabolism in cancer_Homo sapiens_hsa052310.78409362
76Prostate cancer_Homo sapiens_hsa052150.78185159
77Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77919757
78Mineral absorption_Homo sapiens_hsa049780.76180317
79Prolactin signaling pathway_Homo sapiens_hsa049170.75816772
80Epstein-Barr virus infection_Homo sapiens_hsa051690.75112924
81Pathways in cancer_Homo sapiens_hsa052000.75012411
82Asthma_Homo sapiens_hsa053100.74420344
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73305732
84Tuberculosis_Homo sapiens_hsa051520.73250644
85Hepatitis C_Homo sapiens_hsa051600.72386124
86Circadian rhythm_Homo sapiens_hsa047100.70910356
87Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70880820
88Colorectal cancer_Homo sapiens_hsa052100.69751263
89Focal adhesion_Homo sapiens_hsa045100.69622360
90Mismatch repair_Homo sapiens_hsa034300.68132660
91Spliceosome_Homo sapiens_hsa030400.66995167
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65816457
93Glycerophospholipid metabolism_Homo sapiens_hsa005640.65001607
94Dorso-ventral axis formation_Homo sapiens_hsa043200.64773039
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.63213779
96Neurotrophin signaling pathway_Homo sapiens_hsa047220.62656916
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.60270477
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.58134982
99Insulin resistance_Homo sapiens_hsa049310.56710266
100Systemic lupus erythematosus_Homo sapiens_hsa053220.56054867
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53558445
102FoxO signaling pathway_Homo sapiens_hsa040680.53487198
103ECM-receptor interaction_Homo sapiens_hsa045120.52969746
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.52705585
105Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51673004
106Rheumatoid arthritis_Homo sapiens_hsa053230.50519262
107MAPK signaling pathway_Homo sapiens_hsa040100.50302996
108Nucleotide excision repair_Homo sapiens_hsa034200.49524841
109Renal cell carcinoma_Homo sapiens_hsa052110.48942771
110PI3K-Akt signaling pathway_Homo sapiens_hsa041510.47973813
111VEGF signaling pathway_Homo sapiens_hsa043700.47942907
112Endometrial cancer_Homo sapiens_hsa052130.47460795
113ErbB signaling pathway_Homo sapiens_hsa040120.47257492
114Proteoglycans in cancer_Homo sapiens_hsa052050.46741596
115Inositol phosphate metabolism_Homo sapiens_hsa005620.45525056
116Rap1 signaling pathway_Homo sapiens_hsa040150.45189602
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44330010
118Type II diabetes mellitus_Homo sapiens_hsa049300.42915971
119mRNA surveillance pathway_Homo sapiens_hsa030150.42906786
120Amoebiasis_Homo sapiens_hsa051460.42692050
121Sphingolipid metabolism_Homo sapiens_hsa006000.42250988
122Arachidonic acid metabolism_Homo sapiens_hsa005900.38363447
123HIF-1 signaling pathway_Homo sapiens_hsa040660.38094148
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35371129
125Phospholipase D signaling pathway_Homo sapiens_hsa040720.34362598
126Long-term potentiation_Homo sapiens_hsa047200.33609638
127Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32961174
128ABC transporters_Homo sapiens_hsa020100.32403491
129Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31806608
130Linoleic acid metabolism_Homo sapiens_hsa005910.31268493

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »