Rank | Gene Set | Z-score |
---|---|---|
1 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.58302487 |
2 | layer formation in cerebral cortex (GO:0021819) | 3.53852132 |
3 | hemidesmosome assembly (GO:0031581) | 3.52615039 |
4 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.50445725 |
5 | plasma membrane repair (GO:0001778) | 3.43430690 |
6 | desmosome organization (GO:0002934) | 3.30981291 |
7 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.22190712 |
8 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.21501176 |
9 | skin morphogenesis (GO:0043589) | 3.21246028 |
10 | synaptic vesicle maturation (GO:0016188) | 3.09933878 |
11 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.08646212 |
12 | protein retention in ER lumen (GO:0006621) | 3.07666110 |
13 | cell communication by electrical coupling (GO:0010644) | 3.06659913 |
14 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.05506563 |
15 | sodium ion export (GO:0071436) | 3.04217790 |
16 | locomotory exploration behavior (GO:0035641) | 3.03962902 |
17 | establishment of nucleus localization (GO:0040023) | 2.99932360 |
18 | Golgi transport vesicle coating (GO:0048200) | 2.97182220 |
19 | COPI coating of Golgi vesicle (GO:0048205) | 2.97182220 |
20 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.96683173 |
21 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.94672395 |
22 | apoptotic cell clearance (GO:0043277) | 2.93090740 |
23 | macroautophagy (GO:0016236) | 2.87752585 |
24 | stress fiber assembly (GO:0043149) | 2.81935590 |
25 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.81299018 |
26 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.79390551 |
27 | regulation of early endosome to late endosome transport (GO:2000641) | 2.77279501 |
28 | barbed-end actin filament capping (GO:0051016) | 2.77190842 |
29 | adherens junction assembly (GO:0034333) | 2.75083199 |
30 | paraxial mesoderm development (GO:0048339) | 2.70799394 |
31 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.70479615 |
32 | endothelial cell chemotaxis (GO:0035767) | 2.68124147 |
33 | cell communication involved in cardiac conduction (GO:0086065) | 2.65081793 |
34 | negative regulation of cell size (GO:0045792) | 2.64678631 |
35 | activation of protein kinase A activity (GO:0034199) | 2.63996253 |
36 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.63546671 |
37 | regulation of fatty acid beta-oxidation (GO:0031998) | 2.63250070 |
38 | endodermal cell differentiation (GO:0035987) | 2.62650268 |
39 | regulation of cholesterol homeostasis (GO:2000188) | 2.58189557 |
40 | regulation of clathrin-mediated endocytosis (GO:2000369) | 2.52928970 |
41 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.52714605 |
42 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.52440741 |
43 | hippo signaling (GO:0035329) | 2.52287991 |
44 | semaphorin-plexin signaling pathway (GO:0071526) | 2.51759164 |
45 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.51220693 |
46 | protein localization to endosome (GO:0036010) | 2.50504591 |
47 | apical protein localization (GO:0045176) | 2.49882616 |
48 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.49382681 |
49 | regulation of hippo signaling (GO:0035330) | 2.47903772 |
50 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.47661745 |
51 | camera-type eye morphogenesis (GO:0048593) | 2.44982531 |
52 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.44250349 |
53 | alpha-linolenic acid metabolic process (GO:0036109) | 2.43614615 |
54 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.42052018 |
55 | axon extension involved in axon guidance (GO:0048846) | 2.42052018 |
56 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.42043226 |
57 | regulation of synapse structural plasticity (GO:0051823) | 2.41165343 |
58 | cell adhesion mediated by integrin (GO:0033627) | 2.39739158 |
59 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.39736327 |
60 | regulation of p38MAPK cascade (GO:1900744) | 2.39555512 |
61 | regulation of establishment of planar polarity (GO:0090175) | 2.39503123 |
62 | dendrite morphogenesis (GO:0048813) | 2.38890807 |
63 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.37733173 |
64 | negative regulation of catenin import into nucleus (GO:0035414) | 2.37637671 |
65 | mating behavior (GO:0007617) | 2.36576101 |
66 | endothelial cell morphogenesis (GO:0001886) | 2.36139031 |
67 | alanine transport (GO:0032328) | 2.34089967 |
68 | positive regulation of receptor recycling (GO:0001921) | 2.32763489 |
69 | cardiac myofibril assembly (GO:0055003) | 2.32441378 |
70 | regulation of ARF protein signal transduction (GO:0032012) | 2.31684660 |
71 | embryonic foregut morphogenesis (GO:0048617) | 2.31389399 |
72 | cell-substrate junction assembly (GO:0007044) | 2.30490327 |
73 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.29739815 |
74 | myelination in peripheral nervous system (GO:0022011) | 2.29717610 |
75 | peripheral nervous system axon ensheathment (GO:0032292) | 2.29717610 |
76 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.29120270 |
77 | activation of Rac GTPase activity (GO:0032863) | 2.28818683 |
78 | cerebellar Purkinje cell layer development (GO:0021680) | 2.28615059 |
79 | glial cell proliferation (GO:0014009) | 2.28032722 |
80 | focal adhesion assembly (GO:0048041) | 2.27809604 |
81 | cell-substrate adherens junction assembly (GO:0007045) | 2.27809604 |
82 | surfactant homeostasis (GO:0043129) | 2.27761468 |
83 | proline transport (GO:0015824) | 2.26304548 |
84 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.26181411 |
85 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.26099019 |
86 | negative regulation of fatty acid transport (GO:2000192) | 2.25974518 |
87 | low-density lipoprotein particle clearance (GO:0034383) | 2.25819723 |
88 | positive regulation of axon extension (GO:0045773) | 2.25762390 |
89 | collagen fibril organization (GO:0030199) | 2.25521057 |
90 | actin filament bundle assembly (GO:0051017) | 2.24705989 |
91 | actin filament bundle organization (GO:0061572) | 2.24705989 |
92 | negative regulation of vascular permeability (GO:0043116) | 2.24343167 |
93 | cellular potassium ion homeostasis (GO:0030007) | 2.24311758 |
94 | regulation of tight junction assembly (GO:2000810) | 2.23963248 |
95 | positive regulation of p38MAPK cascade (GO:1900745) | 2.23813360 |
96 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.23003332 |
97 | cell migration in hindbrain (GO:0021535) | 2.22766661 |
98 | gap junction assembly (GO:0016264) | 2.22677491 |
99 | basement membrane organization (GO:0071711) | 2.22268547 |
100 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.21295253 |
101 | neuromuscular process controlling balance (GO:0050885) | 2.21069289 |
102 | cerebellar granule cell differentiation (GO:0021707) | 2.20981767 |
103 | vocalization behavior (GO:0071625) | 2.19726893 |
104 | glutamate secretion (GO:0014047) | 2.19421840 |
105 | eye morphogenesis (GO:0048592) | 2.18541527 |
106 | peptidyl-lysine dimethylation (GO:0018027) | 2.18452568 |
107 | amino acid import (GO:0043090) | 2.18004451 |
108 | positive regulation of synapse maturation (GO:0090129) | 2.17947286 |
109 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.17938651 |
110 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.17938651 |
111 | cell junction maintenance (GO:0034331) | 2.17726831 |
112 | asymmetric protein localization (GO:0008105) | 2.17609306 |
113 | axon extension (GO:0048675) | 2.17475747 |
114 | neuron projection extension (GO:1990138) | 2.16955030 |
115 | positive regulation of glycogen metabolic process (GO:0070875) | 2.16794884 |
116 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.15619575 |
117 | chondrocyte proliferation (GO:0035988) | 2.15250620 |
118 | cell junction assembly (GO:0034329) | 2.15137146 |
119 | epithelial cell-cell adhesion (GO:0090136) | 2.14629893 |
120 | negative regulation of sodium ion transport (GO:0010766) | 2.13813171 |
121 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 2.13574965 |
122 | establishment of apical/basal cell polarity (GO:0035089) | 2.12721581 |
123 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.12533725 |
124 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.11536113 |
125 | convergent extension (GO:0060026) | 2.11471046 |
126 | endocytic recycling (GO:0032456) | 2.11120623 |
127 | polarized epithelial cell differentiation (GO:0030859) | 2.10975042 |
128 | growth hormone receptor signaling pathway (GO:0060396) | 2.10302495 |
129 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.10202121 |
130 | dendritic spine morphogenesis (GO:0060997) | 2.09972429 |
131 | cell volume homeostasis (GO:0006884) | 2.09968488 |
132 | carnitine shuttle (GO:0006853) | 2.09848386 |
133 | neural tube development (GO:0021915) | 2.08933313 |
134 | regulation of ARF GTPase activity (GO:0032312) | 2.08930161 |
135 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.08664467 |
136 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.08437750 |
137 | neuron remodeling (GO:0016322) | 2.08174655 |
138 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.08160021 |
139 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.08134759 |
140 | blood vessel endothelial cell migration (GO:0043534) | 2.07640599 |
141 | midgut development (GO:0007494) | 2.06458799 |
142 | fatty acid transmembrane transport (GO:1902001) | 2.05829967 |
143 | gastrulation with mouth forming second (GO:0001702) | 2.05721264 |
144 | adherens junction organization (GO:0034332) | 2.05670775 |
145 | lysine metabolic process (GO:0006553) | 2.04654082 |
146 | lysine catabolic process (GO:0006554) | 2.04654082 |
147 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.04443698 |
148 | cellular sodium ion homeostasis (GO:0006883) | 2.03361807 |
149 | membrane repolarization during action potential (GO:0086011) | 2.02152932 |
150 | protein targeting to plasma membrane (GO:0072661) | 2.02042540 |
151 | cell-cell junction maintenance (GO:0045217) | 2.01308177 |
152 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.01028647 |
153 | growth hormone secretion (GO:0030252) | 1.98987734 |
154 | vascular endothelial growth factor signaling pathway (GO:0038084) | 1.98948199 |
155 | positive regulation of fatty acid oxidation (GO:0046321) | 1.98335354 |
156 | regulation of cholesterol storage (GO:0010885) | 1.98147809 |
157 | protein heterotrimerization (GO:0070208) | 1.97469480 |
158 | regulation of fatty acid oxidation (GO:0046320) | 1.95812743 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.39644467 |
2 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.36073200 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.08893529 |
4 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.02077979 |
5 | KDM2B_26808549_Chip-Seq_K562_Human | 1.96403926 |
6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.91000924 |
7 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.90563225 |
8 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.88452608 |
9 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.88199726 |
10 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.87168644 |
11 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.85835100 |
12 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.83666725 |
13 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.83386232 |
14 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.82431596 |
15 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.80295552 |
16 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.79547141 |
17 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.78082523 |
18 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.74176073 |
19 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.73833587 |
20 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.73022646 |
21 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.71152078 |
22 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.69549552 |
23 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.69332055 |
24 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.66784531 |
25 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.61784069 |
26 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.60457185 |
27 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.56344958 |
28 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.56183174 |
29 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.54559070 |
30 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.54121585 |
31 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.53345372 |
32 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.53345372 |
33 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.52834506 |
34 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.49988514 |
35 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.49629948 |
36 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.49210139 |
37 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.47828144 |
38 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.47317089 |
39 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.46267026 |
40 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.46260240 |
41 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.46071914 |
42 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.44434139 |
43 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.40030968 |
44 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.39778993 |
45 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.39520355 |
46 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.39020863 |
47 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.36288762 |
48 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.36149303 |
49 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.35988466 |
50 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.35538262 |
51 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.29917606 |
52 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.28217716 |
53 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.26489126 |
54 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.26251980 |
55 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.25750643 |
56 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.25256953 |
57 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.24336530 |
58 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.22638101 |
59 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.21976788 |
60 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.21976788 |
61 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.21281983 |
62 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.21132007 |
63 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.20500579 |
64 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.19264031 |
65 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.19212815 |
66 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.19018932 |
67 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.18571451 |
68 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.18281914 |
69 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.17671192 |
70 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.17670948 |
71 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.17588654 |
72 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.16265042 |
73 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.16224507 |
74 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.15698862 |
75 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.15318982 |
76 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.15202860 |
77 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.13157480 |
78 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.12368443 |
79 | * TP53_22127205_ChIP-Seq_IMR90_Human | 1.11642070 |
80 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.11132169 |
81 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.10941057 |
82 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.10088024 |
83 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09891469 |
84 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.08978944 |
85 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.08921669 |
86 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.08643546 |
87 | * SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.08172406 |
88 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.08015024 |
89 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.07379444 |
90 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.07207339 |
91 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.07068028 |
92 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.06923432 |
93 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.06808939 |
94 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.06808939 |
95 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.06776002 |
96 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.06684678 |
97 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.06290536 |
98 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.05878907 |
99 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.04760408 |
100 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.04541768 |
101 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.03772094 |
102 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.03537890 |
103 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.03494108 |
104 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02676478 |
105 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.02632585 |
106 | TP53_16413492_ChIP-PET_HCT116_Human | 1.01478604 |
107 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.01029881 |
108 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.00932591 |
109 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.00727422 |
110 | AR_19668381_ChIP-Seq_PC3_Human | 1.00706038 |
111 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.00497843 |
112 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.00483247 |
113 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00140692 |
114 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.99544203 |
115 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.99459745 |
116 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.97227730 |
117 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.96803483 |
118 | ATF3_27146783_Chip-Seq_COLON_Human | 0.96765464 |
119 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.95980793 |
120 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.95965923 |
121 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.94446312 |
122 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94099886 |
123 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.93590909 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.41600014 |
2 | MP0004859_abnormal_synaptic_plasticity | 3.14361034 |
3 | MP0005409_darkened_coat_color | 2.55220237 |
4 | MP0009780_abnormal_chondrocyte_physiolo | 2.46035385 |
5 | MP0008438_abnormal_cutaneous_collagen | 2.44247443 |
6 | MP0004272_abnormal_basement_membrane | 2.41482196 |
7 | MP0005623_abnormal_meninges_morphology | 2.40644499 |
8 | MP0010234_abnormal_vibrissa_follicle | 2.31748022 |
9 | MP0003283_abnormal_digestive_organ | 2.31111528 |
10 | MP0004858_abnormal_nervous_system | 2.25189007 |
11 | MP0000569_abnormal_digit_pigmentation | 2.22738136 |
12 | MP0005360_urolithiasis | 2.02657894 |
13 | MP0000751_myopathy | 2.00084933 |
14 | MP0010368_abnormal_lymphatic_system | 1.88377499 |
15 | MP0004084_abnormal_cardiac_muscle | 1.88190537 |
16 | MP0002139_abnormal_hepatobiliary_system | 1.85971577 |
17 | MP0005167_abnormal_blood-brain_barrier | 1.83194280 |
18 | MP0003252_abnormal_bile_duct | 1.81715173 |
19 | MP0000579_abnormal_nail_morphology | 1.80340894 |
20 | MP0005076_abnormal_cell_differentiation | 1.80075493 |
21 | MP0000537_abnormal_urethra_morphology | 1.72413114 |
22 | MP0008961_abnormal_basal_metabolism | 1.72317418 |
23 | MP0010030_abnormal_orbit_morphology | 1.64439563 |
24 | MP0003566_abnormal_cell_adhesion | 1.61796657 |
25 | MP0004130_abnormal_muscle_cell | 1.60695336 |
26 | MP0002909_abnormal_adrenal_gland | 1.54368599 |
27 | MP0003941_abnormal_skin_development | 1.53215670 |
28 | MP0003045_fibrosis | 1.52867760 |
29 | MP0002796_impaired_skin_barrier | 1.49808431 |
30 | MP0002060_abnormal_skin_morphology | 1.48138491 |
31 | MP0001958_emphysema | 1.45820545 |
32 | MP0006138_congestive_heart_failure | 1.43247142 |
33 | MP0004233_abnormal_muscle_weight | 1.42509329 |
34 | MP0005275_abnormal_skin_tensile | 1.42040183 |
35 | MP0003091_abnormal_cell_migration | 1.40953846 |
36 | MP0004270_analgesia | 1.39587041 |
37 | MP0010352_gastrointestinal_tract_polyps | 1.38386092 |
38 | MP0005187_abnormal_penis_morphology | 1.37258146 |
39 | MP0000566_synostosis | 1.36462313 |
40 | MP0003300_gastrointestinal_ulcer | 1.35882226 |
41 | MP0004185_abnormal_adipocyte_glucose | 1.34210506 |
42 | MP0000762_abnormal_tongue_morphology | 1.33559582 |
43 | MP0003329_amyloid_beta_deposits | 1.33232980 |
44 | MP0004087_abnormal_muscle_fiber | 1.32414551 |
45 | MP0001849_ear_inflammation | 1.32059083 |
46 | MP0002837_dystrophic_cardiac_calcinosis | 1.31966194 |
47 | MP0003453_abnormal_keratinocyte_physiol | 1.31680052 |
48 | MP0000013_abnormal_adipose_tissue | 1.28895685 |
49 | MP0001348_abnormal_lacrimal_gland | 1.28161957 |
50 | MP0003115_abnormal_respiratory_system | 1.27764445 |
51 | MP0000534_abnormal_ureter_morphology | 1.26525648 |
52 | MP0000462_abnormal_digestive_system | 1.26500149 |
53 | MP0000003_abnormal_adipose_tissue | 1.26006238 |
54 | MP0005248_abnormal_Harderian_gland | 1.25330203 |
55 | MP0010329_abnormal_lipoprotein_level | 1.24652429 |
56 | MP0002896_abnormal_bone_mineralization | 1.24099643 |
57 | MP0005666_abnormal_adipose_tissue | 1.20388113 |
58 | MP0005365_abnormal_bile_salt | 1.20224428 |
59 | MP0003635_abnormal_synaptic_transmissio | 1.19731195 |
60 | MP0005085_abnormal_gallbladder_physiolo | 1.19156686 |
61 | MP0005375_adipose_tissue_phenotype | 1.18666626 |
62 | MP0004885_abnormal_endolymph | 1.17954549 |
63 | MP0002249_abnormal_larynx_morphology | 1.16733884 |
64 | MP0000733_abnormal_muscle_development | 1.15277906 |
65 | MP0003279_aneurysm | 1.14357379 |
66 | MP0009840_abnormal_foam_cell | 1.14133633 |
67 | MP0002877_abnormal_melanocyte_morpholog | 1.11534557 |
68 | MP0009053_abnormal_anal_canal | 1.11175892 |
69 | MP0003634_abnormal_glial_cell | 1.10053549 |
70 | MP0010630_abnormal_cardiac_muscle | 1.07970373 |
71 | MP0005508_abnormal_skeleton_morphology | 1.05440115 |
72 | MP0000467_abnormal_esophagus_morphology | 1.04280043 |
73 | MP0001879_abnormal_lymphatic_vessel | 1.03594555 |
74 | MP0000428_abnormal_craniofacial_morphol | 1.02891272 |
75 | MP0004036_abnormal_muscle_relaxation | 1.02471260 |
76 | MP0003385_abnormal_body_wall | 1.02261843 |
77 | MP0003119_abnormal_digestive_system | 1.02146369 |
78 | MP0005670_abnormal_white_adipose | 1.02134616 |
79 | MP0003879_abnormal_hair_cell | 1.01132456 |
80 | MP0005058_abnormal_lysosome_morphology | 1.00870059 |
81 | MP0001299_abnormal_eye_distance/ | 1.00741556 |
82 | MP0005501_abnormal_skin_physiology | 0.99716817 |
83 | MP0009384_cardiac_valve_regurgitation | 0.99657341 |
84 | MP0002089_abnormal_postnatal_growth/wei | 0.96156486 |
85 | MP0002269_muscular_atrophy | 0.95398740 |
86 | MP0002168_other_aberrant_phenotype | 0.94163263 |
87 | MP0000678_abnormal_parathyroid_gland | 0.94074937 |
88 | MP0005257_abnormal_intraocular_pressure | 0.89452766 |
89 | MP0005595_abnormal_vascular_smooth | 0.89167136 |
90 | MP0005330_cardiomyopathy | 0.88820657 |
91 | MP0002063_abnormal_learning/memory/cond | 0.86999589 |
92 | MP0001915_intracranial_hemorrhage | 0.86519768 |
93 | MP0008775_abnormal_heart_ventricle | 0.85792035 |
94 | MP0004782_abnormal_surfactant_physiolog | 0.85288568 |
95 | MP0002108_abnormal_muscle_morphology | 0.84549807 |
96 | MP0000747_muscle_weakness | 0.84543958 |
97 | MP0000759_abnormal_skeletal_muscle | 0.83545680 |
98 | MP0004085_abnormal_heartbeat | 0.83510213 |
99 | MP0004215_abnormal_myocardial_fiber | 0.82211660 |
100 | MP0005385_cardiovascular_system_phenoty | 0.80806542 |
101 | MP0001544_abnormal_cardiovascular_syste | 0.80806542 |
102 | MP0002697_abnormal_eye_size | 0.80648261 |
103 | MP0004264_abnormal_extraembryonic_tissu | 0.80438413 |
104 | MP0003123_paternal_imprinting | 0.79841653 |
105 | MP0002972_abnormal_cardiac_muscle | 0.79835280 |
106 | MP0003191_abnormal_cellular_cholesterol | 0.78765073 |
107 | MP0005620_abnormal_muscle_contractility | 0.78586962 |
108 | MP0003950_abnormal_plasma_membrane | 0.78189115 |
109 | MP0002295_abnormal_pulmonary_circulatio | 0.78083877 |
110 | MP0002925_abnormal_cardiovascular_devel | 0.77649946 |
111 | MP0000767_abnormal_smooth_muscle | 0.77288896 |
112 | MP0000778_abnormal_nervous_system | 0.77225911 |
113 | MP0005503_abnormal_tendon_morphology | 0.76272674 |
114 | MP0003122_maternal_imprinting | 0.75648170 |
115 | MP0000432_abnormal_head_morphology | 0.75143230 |
116 | MP0000604_amyloidosis | 0.74679433 |
117 | MP0003878_abnormal_ear_physiology | 0.74125320 |
118 | MP0005377_hearing/vestibular/ear_phenot | 0.74125320 |
119 | MP0002234_abnormal_pharynx_morphology | 0.73956675 |
120 | MP0002116_abnormal_craniofacial_bone | 0.72528528 |
121 | MP0003942_abnormal_urinary_system | 0.72379219 |
122 | MP0009672_abnormal_birth_weight | 0.72340653 |
123 | MP0005023_abnormal_wound_healing | 0.72223176 |
124 | MP0002128_abnormal_blood_circulation | 0.72125022 |
125 | MP0001177_atelectasis | 0.71710970 |
126 | MP0002118_abnormal_lipid_homeostasis | 0.71201017 |
127 | MP0004811_abnormal_neuron_physiology | 0.70948038 |
128 | MP0002090_abnormal_vision | 0.69930857 |
129 | MP0002653_abnormal_ependyma_morphology | 0.69729784 |
130 | MP0001614_abnormal_blood_vessel | 0.69356314 |
131 | MP0000266_abnormal_heart_morphology | 0.69190956 |
132 | MP0010771_integument_phenotype | 0.68907879 |
133 | MP0004145_abnormal_muscle_electrophysio | 0.68817127 |
134 | MP0003935_abnormal_craniofacial_develop | 0.68590623 |
135 | MP0005451_abnormal_body_composition | 0.67883870 |
136 | MP0002098_abnormal_vibrissa_morphology | 0.66237043 |
137 | MP0003690_abnormal_glial_cell | 0.65464696 |
138 | MP0009250_abnormal_appendicular_skeleto | 0.63919013 |
139 | MP0000920_abnormal_myelination | 0.59932008 |
140 | MP0010678_abnormal_skin_adnexa | 0.59677571 |
141 | MP0002092_abnormal_eye_morphology | 0.59443504 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Cerebral aneurysm (HP:0004944) | 3.49798602 |
2 | Shallow orbits (HP:0000586) | 3.28673777 |
3 | Protrusio acetabuli (HP:0003179) | 3.18861937 |
4 | Vascular tortuosity (HP:0004948) | 3.11264884 |
5 | Distal upper limb amyotrophy (HP:0007149) | 2.97139769 |
6 | Upper limb amyotrophy (HP:0009129) | 2.97139769 |
7 | Abnormality of the lower motor neuron (HP:0002366) | 2.86191437 |
8 | Lymphangioma (HP:0100764) | 2.80086813 |
9 | Obstructive sleep apnea (HP:0002870) | 2.72722314 |
10 | Hand muscle atrophy (HP:0009130) | 2.72436564 |
11 | Hyperacusis (HP:0010780) | 2.69240528 |
12 | Neurofibrillary tangles (HP:0002185) | 2.58842011 |
13 | Broad metatarsal (HP:0001783) | 2.55943224 |
14 | Ulnar bowing (HP:0003031) | 2.53761299 |
15 | Premature rupture of membranes (HP:0001788) | 2.49153392 |
16 | Deep venous thrombosis (HP:0002625) | 2.49146844 |
17 | Aneurysm (HP:0002617) | 2.48232184 |
18 | Bladder diverticulum (HP:0000015) | 2.48117433 |
19 | Ankle contracture (HP:0006466) | 2.47564344 |
20 | Turricephaly (HP:0000262) | 2.47530278 |
21 | Broad face (HP:0000283) | 2.47484720 |
22 | Neonatal short-limb short stature (HP:0008921) | 2.45237494 |
23 | Wormian bones (HP:0002645) | 2.44193695 |
24 | Subacute progressive viral hepatitis (HP:0006572) | 2.42471074 |
25 | Cervical subluxation (HP:0003308) | 2.42068282 |
26 | Elfin facies (HP:0004428) | 2.41702806 |
27 | Increased connective tissue (HP:0009025) | 2.39211770 |
28 | Distal lower limb amyotrophy (HP:0008944) | 2.32912010 |
29 | Mitral valve prolapse (HP:0001634) | 2.32225778 |
30 | Renovascular hypertension (HP:0100817) | 2.29274441 |
31 | Enlarged penis (HP:0000040) | 2.25311768 |
32 | Right ventricular cardiomyopathy (HP:0011663) | 2.23956118 |
33 | Hyporeflexia of lower limbs (HP:0002600) | 2.18474766 |
34 | Short nail (HP:0001799) | 2.17565149 |
35 | Insomnia (HP:0100785) | 2.17238137 |
36 | Abnormality of dentin (HP:0010299) | 2.16826704 |
37 | Long toe (HP:0010511) | 2.13460680 |
38 | Mitral regurgitation (HP:0001653) | 2.13438821 |
39 | Aortic aneurysm (HP:0004942) | 2.12414075 |
40 | Flat acetabular roof (HP:0003180) | 2.12224517 |
41 | Difficulty running (HP:0009046) | 2.09755318 |
42 | Macroorchidism (HP:0000053) | 2.08929033 |
43 | Vertebral compression fractures (HP:0002953) | 2.08233143 |
44 | Bundle branch block (HP:0011710) | 2.08225440 |
45 | Renal duplication (HP:0000075) | 2.05234451 |
46 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.02867096 |
47 | Aplasia of the phalanges of the hand (HP:0009802) | 2.02867096 |
48 | Aplasia involving bones of the extremities (HP:0009825) | 2.02867096 |
49 | Distal lower limb muscle weakness (HP:0009053) | 2.01284071 |
50 | Difficulty climbing stairs (HP:0003551) | 2.01005849 |
51 | Bowel diverticulosis (HP:0005222) | 2.00891382 |
52 | Dysmetric saccades (HP:0000641) | 1.99289301 |
53 | Vertebral arch anomaly (HP:0008438) | 1.99143202 |
54 | Advanced eruption of teeth (HP:0006288) | 1.98478812 |
55 | Osteolytic defects of the hand bones (HP:0009699) | 1.97999611 |
56 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.97999611 |
57 | Asymmetry of the thorax (HP:0001555) | 1.97877487 |
58 | Disproportionate tall stature (HP:0001519) | 1.97470589 |
59 | Blue sclerae (HP:0000592) | 1.97179335 |
60 | Increased variability in muscle fiber diameter (HP:0003557) | 1.96028113 |
61 | Pointed chin (HP:0000307) | 1.94972449 |
62 | Bronchomalacia (HP:0002780) | 1.94726193 |
63 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.93025678 |
64 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.92556335 |
65 | Action tremor (HP:0002345) | 1.92316408 |
66 | Soft skin (HP:0000977) | 1.91172724 |
67 | Hemiplegia (HP:0002301) | 1.89743369 |
68 | Dilatation of the ascending aorta (HP:0005111) | 1.89221331 |
69 | Aortic dissection (HP:0002647) | 1.88735986 |
70 | Sudden death (HP:0001699) | 1.87875538 |
71 | Natal tooth (HP:0000695) | 1.86545542 |
72 | Abnormality of the Achilles tendon (HP:0005109) | 1.84763904 |
73 | Atrophic scars (HP:0001075) | 1.82179591 |
74 | Ventricular fibrillation (HP:0001663) | 1.81448676 |
75 | Joint laxity (HP:0001388) | 1.81387783 |
76 | Achilles tendon contracture (HP:0001771) | 1.81356473 |
77 | Genu recurvatum (HP:0002816) | 1.80805152 |
78 | Buphthalmos (HP:0000557) | 1.80447545 |
79 | Overgrowth (HP:0001548) | 1.78430116 |
80 | Lower limb amyotrophy (HP:0007210) | 1.78137604 |
81 | Scapular winging (HP:0003691) | 1.77769201 |
82 | Striae distensae (HP:0001065) | 1.77756756 |
83 | Overriding aorta (HP:0002623) | 1.76230883 |
84 | Spinal cord compression (HP:0002176) | 1.75505482 |
85 | Short 4th metacarpal (HP:0010044) | 1.74870404 |
86 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.74870404 |
87 | Thin bony cortex (HP:0002753) | 1.74699475 |
88 | Coronal craniosynostosis (HP:0004440) | 1.73916716 |
89 | Hepatoblastoma (HP:0002884) | 1.73415959 |
90 | Hammertoe (HP:0001765) | 1.71236564 |
91 | Back pain (HP:0003418) | 1.70759975 |
92 | Focal segmental glomerulosclerosis (HP:0000097) | 1.70411321 |
93 | Cerebral inclusion bodies (HP:0100314) | 1.70247423 |
94 | Biconcave vertebral bodies (HP:0004586) | 1.69823722 |
95 | Flat cornea (HP:0007720) | 1.69676926 |
96 | Abnormality of the 4th metacarpal (HP:0010012) | 1.68916884 |
97 | Mitral stenosis (HP:0001718) | 1.68897433 |
98 | Myokymia (HP:0002411) | 1.68663431 |
99 | Wide anterior fontanel (HP:0000260) | 1.68503579 |
100 | Deviation of the hallux (HP:0010051) | 1.68396351 |
101 | Neoplasm of the heart (HP:0100544) | 1.68054347 |
102 | Ankyloglossia (HP:0010296) | 1.67794554 |
103 | Insidious onset (HP:0003587) | 1.65933822 |
104 | Termporal pattern (HP:0011008) | 1.65933822 |
105 | Hallux valgus (HP:0001822) | 1.65229770 |
106 | Spinal rigidity (HP:0003306) | 1.65169279 |
107 | Ankle clonus (HP:0011448) | 1.64689639 |
108 | Hypoventilation (HP:0002791) | 1.64329575 |
109 | Rectal prolapse (HP:0002035) | 1.63511684 |
110 | Genetic anticipation (HP:0003743) | 1.62137433 |
111 | Nuclear cataract (HP:0100018) | 1.61930316 |
112 | Abnormality of the acetabulum (HP:0003170) | 1.61184935 |
113 | Abnormality of the astrocytes (HP:0100707) | 1.61159354 |
114 | Astrocytoma (HP:0009592) | 1.61159354 |
115 | Type 1 muscle fiber predominance (HP:0003803) | 1.60423603 |
116 | Hyperparathyroidism (HP:0000843) | 1.59384196 |
117 | Xanthomatosis (HP:0000991) | 1.58666364 |
118 | Abnormal ossification of hand bones (HP:0005921) | 1.57936598 |
119 | Precocious puberty (HP:0000826) | 1.57091318 |
120 | Visceral angiomatosis (HP:0100761) | 1.56755049 |
121 | Torticollis (HP:0000473) | 1.56202504 |
122 | Fibroma (HP:0010614) | 1.56009296 |
123 | Skin nodule (HP:0200036) | 1.55888958 |
124 | Hyperextensible skin (HP:0000974) | 1.55540242 |
125 | Congenital glaucoma (HP:0001087) | 1.55037231 |
126 | Neonatal death (HP:0003811) | 1.54805332 |
127 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.54458546 |
128 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.54265592 |
129 | Peritonitis (HP:0002586) | 1.53745636 |
130 | Atrioventricular block (HP:0001678) | 1.53737336 |
131 | Fragile skin (HP:0001030) | 1.51951497 |
132 | Hemangiomatosis (HP:0007461) | 1.51662384 |
133 | Supranuclear gaze palsy (HP:0000605) | 1.51659883 |
134 | Bowing of the arm (HP:0006488) | 1.51346266 |
135 | Bowed forearm bones (HP:0003956) | 1.51346266 |
136 | Esophageal varix (HP:0002040) | 1.50220331 |
137 | Muscle fiber splitting (HP:0003555) | 1.50172050 |
138 | Resting tremor (HP:0002322) | 1.50115721 |
139 | Elbow flexion contracture (HP:0002987) | 1.50093973 |
140 | Hypoplastic ischia (HP:0003175) | 1.49992726 |
141 | Long palpebral fissure (HP:0000637) | 1.49835760 |
142 | Epidermoid cyst (HP:0200040) | 1.49797903 |
143 | Aortic regurgitation (HP:0001659) | 1.49718558 |
144 | Hamartoma of the eye (HP:0010568) | 1.49605183 |
145 | Arnold-Chiari malformation (HP:0002308) | 1.48201409 |
146 | Arterial tortuosity (HP:0005116) | 1.48048968 |
147 | Wrist flexion contracture (HP:0001239) | 1.47487366 |
148 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.46433748 |
149 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.45857548 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.92819677 |
2 | RIPK1 | 2.99219150 |
3 | PKN2 | 2.95916054 |
4 | LATS2 | 2.50632458 |
5 | PRKD3 | 2.43517340 |
6 | LATS1 | 2.34894520 |
7 | MAP3K9 | 2.30986026 |
8 | PDGFRA | 2.19854612 |
9 | TTN | 2.12050700 |
10 | SMG1 | 1.93977181 |
11 | PAK6 | 1.84333027 |
12 | DDR2 | 1.80743718 |
13 | KSR2 | 1.79328042 |
14 | PTK6 | 1.78474677 |
15 | DAPK2 | 1.74790921 |
16 | LMTK2 | 1.71600429 |
17 | MARK1 | 1.66057359 |
18 | TYRO3 | 1.64476239 |
19 | ICK | 1.62200597 |
20 | CAMK1G | 1.55467171 |
21 | SIK1 | 1.52138034 |
22 | CDK12 | 1.51808007 |
23 | CAMKK1 | 1.48190917 |
24 | CAMK1D | 1.44939310 |
25 | DMPK | 1.44746855 |
26 | TAOK1 | 1.44548088 |
27 | ERN1 | 1.41939721 |
28 | STK38 | 1.41727830 |
29 | BMX | 1.40821890 |
30 | PRPF4B | 1.37803991 |
31 | PTK2 | 1.36301815 |
32 | NTRK1 | 1.31339796 |
33 | TESK1 | 1.30228452 |
34 | RET | 1.29702800 |
35 | EPHB2 | 1.27238889 |
36 | MAP3K4 | 1.26099722 |
37 | FER | 1.26099372 |
38 | NTRK3 | 1.25254411 |
39 | MAP3K2 | 1.21335804 |
40 | IRAK3 | 1.20159464 |
41 | PAK3 | 1.16233330 |
42 | SCYL2 | 1.13939515 |
43 | MAP3K10 | 1.09250823 |
44 | MINK1 | 1.06318577 |
45 | ALK | 1.04785939 |
46 | KSR1 | 1.03806768 |
47 | EPHA4 | 1.01553858 |
48 | NEK1 | 1.01383376 |
49 | MYLK | 0.99417720 |
50 | * MTOR | 0.98806254 |
51 | PHKG2 | 0.98245277 |
52 | PHKG1 | 0.98245277 |
53 | ARAF | 0.96827381 |
54 | EEF2K | 0.96752946 |
55 | PAK2 | 0.92511135 |
56 | MET | 0.90304072 |
57 | PDGFRB | 0.90019219 |
58 | PRKCH | 0.88480913 |
59 | PRKD2 | 0.87495483 |
60 | TIE1 | 0.86823184 |
61 | MAP2K4 | 0.86391509 |
62 | CDC42BPA | 0.85486421 |
63 | MST1R | 0.83768747 |
64 | SIK2 | 0.82841673 |
65 | PTK2B | 0.80575600 |
66 | ROCK2 | 0.77942417 |
67 | SGK3 | 0.75848439 |
68 | MOS | 0.75403221 |
69 | FGFR1 | 0.73374479 |
70 | PAK4 | 0.72888118 |
71 | FGFR4 | 0.72356527 |
72 | MAP3K7 | 0.71510834 |
73 | NTRK2 | 0.71477405 |
74 | LIMK1 | 0.70738082 |
75 | ERBB2 | 0.70465577 |
76 | STK11 | 0.67570731 |
77 | ROCK1 | 0.67339476 |
78 | EPHA2 | 0.66634776 |
79 | FGFR2 | 0.66039725 |
80 | PRKD1 | 0.61528652 |
81 | CDK5 | 0.61480854 |
82 | CAMK2B | 0.61299852 |
83 | MARK2 | 0.59992034 |
84 | MAP2K1 | 0.59722715 |
85 | NEK9 | 0.59209721 |
86 | EPHB1 | 0.59048477 |
87 | PDPK1 | 0.58231910 |
88 | MAP3K6 | 0.57869279 |
89 | AKT3 | 0.57363286 |
90 | WNK1 | 0.57295295 |
91 | CAMK2G | 0.55926564 |
92 | PRKAA1 | 0.54420060 |
93 | RPS6KA2 | 0.53184646 |
94 | SGK494 | 0.52881172 |
95 | SGK223 | 0.52881172 |
96 | STK38L | 0.50778706 |
97 | NEK6 | 0.50249115 |
98 | MAP3K13 | 0.48216636 |
99 | PRKCZ | 0.47955060 |
100 | CDK15 | 0.47510043 |
101 | FRK | 0.46519405 |
102 | ILK | 0.46464975 |
103 | TRPM7 | 0.46411058 |
104 | MAPKAPK3 | 0.46121751 |
105 | MAP3K1 | 0.45939831 |
106 | CDK18 | 0.43276135 |
107 | CDK11A | 0.42799356 |
108 | STK3 | 0.42752357 |
109 | CDK6 | 0.42111404 |
110 | CAMK2D | 0.41705623 |
111 | TGFBR2 | 0.40317165 |
112 | RPS6KA3 | 0.40130164 |
113 | CAMK4 | 0.39836727 |
114 | RPS6KC1 | 0.39444024 |
115 | RPS6KL1 | 0.39444024 |
116 | BRAF | 0.39131728 |
117 | AKT2 | 0.37764230 |
118 | PDK1 | 0.37375962 |
119 | SGK1 | 0.37279151 |
120 | LRRK2 | 0.37180001 |
121 | SRC | 0.37143311 |
122 | MAP2K2 | 0.36540366 |
123 | GSK3A | 0.36189881 |
124 | MAP3K3 | 0.35458676 |
125 | PRKG2 | 0.34955023 |
126 | ERBB4 | 0.34411083 |
127 | WNK4 | 0.34268524 |
128 | FGFR3 | 0.33961686 |
129 | PDK3 | 0.33376795 |
130 | PDK4 | 0.33376795 |
131 | DAPK3 | 0.31504597 |
132 | MAPK10 | 0.30715952 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.10426669 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.00336310 |
3 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.68272481 |
4 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.62634668 |
5 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.57284929 |
6 | Bile secretion_Homo sapiens_hsa04976 | 1.56559038 |
7 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.46913258 |
8 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.33681507 |
9 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.33178164 |
10 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.30687821 |
11 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.29073177 |
12 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.25743384 |
13 | Focal adhesion_Homo sapiens_hsa04510 | 1.25403548 |
14 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.23617449 |
15 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.23163294 |
16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.20793055 |
17 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.19428418 |
18 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.18501984 |
19 | Thyroid cancer_Homo sapiens_hsa05216 | 1.17414014 |
20 | Lysine degradation_Homo sapiens_hsa00310 | 1.16074630 |
21 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.15691669 |
22 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.13966963 |
23 | Adherens junction_Homo sapiens_hsa04520 | 1.13949074 |
24 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.13608981 |
25 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.13547130 |
26 | Glioma_Homo sapiens_hsa05214 | 1.11854991 |
27 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.09937994 |
28 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.09826438 |
29 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.08325035 |
30 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.07441520 |
31 | Amoebiasis_Homo sapiens_hsa05146 | 1.05077734 |
32 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.03420652 |
33 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.02968643 |
34 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.02868974 |
35 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.02648724 |
36 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.02558067 |
37 | Circadian entrainment_Homo sapiens_hsa04713 | 1.01626490 |
38 | Insulin resistance_Homo sapiens_hsa04931 | 1.01259890 |
39 | Insulin secretion_Homo sapiens_hsa04911 | 1.00394144 |
40 | Endometrial cancer_Homo sapiens_hsa05213 | 0.98609029 |
41 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.98320572 |
42 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.98006576 |
43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.97612418 |
44 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.97075803 |
45 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.95094950 |
46 | Salivary secretion_Homo sapiens_hsa04970 | 0.95071934 |
47 | Gap junction_Homo sapiens_hsa04540 | 0.94991450 |
48 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.93432494 |
49 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.92570647 |
50 | Renin secretion_Homo sapiens_hsa04924 | 0.92345667 |
51 | Axon guidance_Homo sapiens_hsa04360 | 0.91956706 |
52 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.91379494 |
53 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.90872582 |
54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.90487639 |
55 | Long-term potentiation_Homo sapiens_hsa04720 | 0.89918108 |
56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.87250858 |
57 | Tight junction_Homo sapiens_hsa04530 | 0.86997303 |
58 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.86975570 |
59 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.86347956 |
60 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.85589704 |
61 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.85463147 |
62 | Melanogenesis_Homo sapiens_hsa04916 | 0.84198347 |
63 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.83867936 |
64 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.83702185 |
65 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.83692215 |
66 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.83430919 |
67 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.83234378 |
68 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.82992149 |
69 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.81476427 |
70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.81359305 |
71 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.80823105 |
72 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.80594354 |
73 | GABAergic synapse_Homo sapiens_hsa04727 | 0.80571356 |
74 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.79999096 |
75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.79352061 |
76 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.78800669 |
77 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.78504133 |
78 | Other glycan degradation_Homo sapiens_hsa00511 | 0.78399856 |
79 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.77949008 |
80 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.76279858 |
81 | Prostate cancer_Homo sapiens_hsa05215 | 0.75251324 |
82 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.75015610 |
83 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.74612296 |
84 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.74144091 |
85 | Bladder cancer_Homo sapiens_hsa05219 | 0.74111864 |
86 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.74106984 |
87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.73839101 |
88 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.73414580 |
89 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.72782084 |
90 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.72253867 |
91 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.71681839 |
92 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.71568155 |
93 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71433060 |
94 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.70912833 |
95 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.70846598 |
96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.69462127 |
97 | Endocytosis_Homo sapiens_hsa04144 | 0.69122632 |
98 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.68818619 |
99 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.68683928 |
100 | Cocaine addiction_Homo sapiens_hsa05030 | 0.68558758 |
101 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.68436867 |
102 | Pathways in cancer_Homo sapiens_hsa05200 | 0.66673774 |
103 | Galactose metabolism_Homo sapiens_hsa00052 | 0.65200482 |
104 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.64474373 |
105 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64180804 |
106 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.63655071 |
107 | Melanoma_Homo sapiens_hsa05218 | 0.63459540 |
108 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.63205138 |
109 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.61835934 |
110 | Prion diseases_Homo sapiens_hsa05020 | 0.61382606 |
111 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.60757906 |
112 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.59477114 |
113 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.59059447 |
114 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.58977125 |
115 | Colorectal cancer_Homo sapiens_hsa05210 | 0.58763591 |
116 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.58577759 |
117 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58550927 |
118 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.58439715 |
119 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.58060076 |
120 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.56402569 |
121 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55636162 |
122 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.54450592 |
123 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.53925483 |
124 | Morphine addiction_Homo sapiens_hsa05032 | 0.53641568 |
125 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.51806604 |