Rank | Gene Set | Z-score |
---|---|---|
1 | hemidesmosome assembly (GO:0031581) | 5.96678015 |
2 | desmosome organization (GO:0002934) | 4.71329075 |
3 | regulation of hippo signaling (GO:0035330) | 4.68780098 |
4 | surfactant homeostasis (GO:0043129) | 4.42616970 |
5 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 4.33058667 |
6 | activation of Rac GTPase activity (GO:0032863) | 4.20057460 |
7 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 4.15910901 |
8 | epithelial cell-cell adhesion (GO:0090136) | 4.10782950 |
9 | establishment of apical/basal cell polarity (GO:0035089) | 4.03943518 |
10 | cell-substrate junction assembly (GO:0007044) | 3.90547240 |
11 | semaphorin-plexin signaling pathway (GO:0071526) | 3.89378403 |
12 | regulation of water loss via skin (GO:0033561) | 3.82408115 |
13 | regulation of cholesterol homeostasis (GO:2000188) | 3.81445211 |
14 | COPI coating of Golgi vesicle (GO:0048205) | 3.81341825 |
15 | Golgi transport vesicle coating (GO:0048200) | 3.81341825 |
16 | regulation of interleukin-13 production (GO:0032656) | 3.79988556 |
17 | ear development (GO:0043583) | 3.75326247 |
18 | intestinal epithelial cell development (GO:0060576) | 3.73760735 |
19 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.70366414 |
20 | cell adhesion mediated by integrin (GO:0033627) | 3.68140048 |
21 | polarized epithelial cell differentiation (GO:0030859) | 3.67258977 |
22 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.53327701 |
23 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 3.53325199 |
24 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.52816285 |
25 | lung epithelium development (GO:0060428) | 3.52702203 |
26 | vitamin transmembrane transport (GO:0035461) | 3.50987288 |
27 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.50457408 |
28 | positive regulation of keratinocyte differentiation (GO:0045618) | 3.49753718 |
29 | regulation of interleukin-5 production (GO:0032674) | 3.48400870 |
30 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.47560928 |
31 | mesodermal cell differentiation (GO:0048333) | 3.45386532 |
32 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.44526871 |
33 | keratinocyte proliferation (GO:0043616) | 3.43408185 |
34 | positive regulation of p38MAPK cascade (GO:1900745) | 3.42868998 |
35 | skin morphogenesis (GO:0043589) | 3.38641821 |
36 | establishment of skin barrier (GO:0061436) | 3.32179899 |
37 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.29531011 |
38 | gap junction assembly (GO:0016264) | 3.26707482 |
39 | chemical homeostasis within a tissue (GO:0048875) | 3.26477560 |
40 | hormone catabolic process (GO:0042447) | 3.25799083 |
41 | renal filtration (GO:0097205) | 3.24764726 |
42 | endothelial cell chemotaxis (GO:0035767) | 3.24676904 |
43 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 3.22353393 |
44 | establishment of monopolar cell polarity (GO:0061162) | 3.22353393 |
45 | glomerular visceral epithelial cell development (GO:0072015) | 3.21743619 |
46 | apical protein localization (GO:0045176) | 3.21518180 |
47 | regulation of fatty acid beta-oxidation (GO:0031998) | 3.20740738 |
48 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.16125367 |
49 | apoptotic process involved in morphogenesis (GO:0060561) | 3.15710585 |
50 | apoptotic cell clearance (GO:0043277) | 3.14682236 |
51 | atrioventricular valve morphogenesis (GO:0003181) | 3.14084454 |
52 | regulation of keratinocyte differentiation (GO:0045616) | 3.13359476 |
53 | multicellular organismal water homeostasis (GO:0050891) | 3.13263368 |
54 | proline biosynthetic process (GO:0006561) | 3.09956543 |
55 | hypotonic response (GO:0006971) | 3.07444324 |
56 | regulation of p38MAPK cascade (GO:1900744) | 3.06098051 |
57 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.04572793 |
58 | regulation of gene silencing by RNA (GO:0060966) | 3.04163190 |
59 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.04163190 |
60 | regulation of gene silencing by miRNA (GO:0060964) | 3.04163190 |
61 | adherens junction assembly (GO:0034333) | 3.01347618 |
62 | trophectodermal cell differentiation (GO:0001829) | 3.01131041 |
63 | keratinization (GO:0031424) | 3.00057760 |
64 | glomerular epithelial cell development (GO:0072310) | 2.98984797 |
65 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.97025846 |
66 | negative regulation of cell size (GO:0045792) | 2.96402729 |
67 | virion attachment to host cell (GO:0019062) | 2.96231192 |
68 | adhesion of symbiont to host cell (GO:0044650) | 2.96231192 |
69 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.95774373 |
70 | protein localization to endosome (GO:0036010) | 2.94608171 |
71 | ectoderm development (GO:0007398) | 2.94298578 |
72 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.93642729 |
73 | striated muscle atrophy (GO:0014891) | 2.91788827 |
74 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.91656598 |
75 | cell-cell junction assembly (GO:0007043) | 2.90342212 |
76 | asymmetric protein localization (GO:0008105) | 2.89682026 |
77 | hippo signaling (GO:0035329) | 2.89044536 |
78 | cell-cell junction maintenance (GO:0045217) | 2.86926322 |
79 | positive regulation of histone deacetylation (GO:0031065) | 2.85516984 |
80 | basement membrane organization (GO:0071711) | 2.85091135 |
81 | positive regulation of epidermis development (GO:0045684) | 2.84852776 |
82 | stress granule assembly (GO:0034063) | 2.84584735 |
83 | epidermal cell differentiation (GO:0009913) | 2.84464653 |
84 | cell-substrate adherens junction assembly (GO:0007045) | 2.83010619 |
85 | focal adhesion assembly (GO:0048041) | 2.83010619 |
86 | maternal placenta development (GO:0001893) | 2.81858785 |
87 | keratinocyte differentiation (GO:0030216) | 2.81248408 |
88 | intestinal cholesterol absorption (GO:0030299) | 2.79269952 |
89 | epidermis development (GO:0008544) | 2.79231909 |
90 | negative regulation of cell fate specification (GO:0009996) | 2.75011500 |
91 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.74042952 |
92 | respiratory tube development (GO:0030323) | 2.73930284 |
93 | endodermal cell differentiation (GO:0035987) | 2.73178013 |
94 | hair cycle (GO:0042633) | 2.70313772 |
95 | molting cycle (GO:0042303) | 2.70313772 |
96 | anterior/posterior axis specification, embryo (GO:0008595) | 2.69596572 |
97 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.68729612 |
98 | sulfur amino acid catabolic process (GO:0000098) | 2.68001051 |
99 | cysteine metabolic process (GO:0006534) | 2.67753330 |
100 | establishment of tissue polarity (GO:0007164) | 2.67408919 |
101 | establishment of planar polarity (GO:0001736) | 2.67408919 |
102 | blood vessel endothelial cell migration (GO:0043534) | 2.67407369 |
103 | embryonic eye morphogenesis (GO:0048048) | 2.67173349 |
104 | protein autoprocessing (GO:0016540) | 2.67159342 |
105 | negative regulation of viral release from host cell (GO:1902187) | 2.66309179 |
106 | cell differentiation involved in embryonic placenta development (GO:0060706) | 2.66213489 |
107 | water homeostasis (GO:0030104) | 2.65459995 |
108 | wound healing, spreading of epidermal cells (GO:0035313) | 2.63540324 |
109 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.63305058 |
110 | regulation of ruffle assembly (GO:1900027) | 2.63149324 |
111 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.62431035 |
112 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.62265608 |
113 | regulation of cholesterol biosynthetic process (GO:0045540) | 2.62147857 |
114 | skeletal muscle adaptation (GO:0043501) | 2.61421772 |
115 | protein retention in ER lumen (GO:0006621) | 2.60531742 |
116 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 2.60455214 |
117 | 4-hydroxyproline metabolic process (GO:0019471) | 2.59837905 |
118 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.59695070 |
119 | adhesion of symbiont to host (GO:0044406) | 2.59619008 |
120 | O-glycan processing (GO:0016266) | 2.58017544 |
121 | interferon-gamma secretion (GO:0072643) | 2.57645626 |
122 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.57358495 |
123 | peptide catabolic process (GO:0043171) | 2.56572279 |
124 | tight junction assembly (GO:0070830) | 2.56203320 |
125 | glomerular basement membrane development (GO:0032836) | 2.56151114 |
126 | renal system development (GO:0072001) | 2.55407928 |
127 | regulation of viral release from host cell (GO:1902186) | 2.55159273 |
128 | intestinal absorption (GO:0050892) | 2.54719791 |
129 | proline metabolic process (GO:0006560) | 2.54532436 |
130 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.54145283 |
131 | morphogenesis of embryonic epithelium (GO:0016331) | 2.52817287 |
132 | cell junction maintenance (GO:0034331) | 2.51612034 |
133 | low-density lipoprotein particle clearance (GO:0034383) | 2.51518956 |
134 | amyloid precursor protein metabolic process (GO:0042982) | 2.51273266 |
135 | embryonic foregut morphogenesis (GO:0048617) | 2.51230886 |
136 | axonemal dynein complex assembly (GO:0070286) | 2.51216476 |
137 | primary alcohol catabolic process (GO:0034310) | 2.51065226 |
138 | receptor catabolic process (GO:0032801) | 2.50964204 |
139 | regulation of Cdc42 GTPase activity (GO:0043088) | 2.50010798 |
140 | establishment of epithelial cell polarity (GO:0090162) | 2.49967386 |
141 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.49391674 |
142 | regulation of keratinocyte proliferation (GO:0010837) | 2.48118969 |
143 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.47957142 |
144 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.47646052 |
145 | peptide cross-linking (GO:0018149) | 2.47206672 |
146 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.46698271 |
147 | regulation of cell fate specification (GO:0042659) | 2.46247085 |
148 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.45863948 |
149 | heterochromatin organization (GO:0070828) | 2.44761951 |
150 | paraxial mesoderm development (GO:0048339) | 2.44307924 |
151 | embryonic placenta development (GO:0001892) | 2.44161256 |
152 | epoxygenase P450 pathway (GO:0019373) | 2.43876003 |
153 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.42035350 |
154 | collecting duct development (GO:0072044) | 2.41282035 |
155 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.38505734 |
156 | lung vasculature development (GO:0060426) | 2.37368030 |
157 | drug catabolic process (GO:0042737) | 2.37180312 |
158 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.35641217 |
159 | lung-associated mesenchyme development (GO:0060484) | 2.34699686 |
160 | regulation of translational fidelity (GO:0006450) | 2.34599491 |
161 | phosphate ion transmembrane transport (GO:0035435) | 2.34050197 |
162 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.33821256 |
163 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.33821256 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 7.97546084 |
2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.65965890 |
3 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.63910806 |
4 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.59964462 |
5 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.58446390 |
6 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.48495198 |
7 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.45977708 |
8 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.43890134 |
9 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.41163961 |
10 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.30342155 |
11 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.30060817 |
12 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.20852199 |
13 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.08835426 |
14 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.98343473 |
15 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.96700682 |
16 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.96700682 |
17 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.96700682 |
18 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.94001542 |
19 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.93751789 |
20 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.92465641 |
21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.92447274 |
22 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.90867031 |
23 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.90835743 |
24 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.90737499 |
25 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.88600784 |
26 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.87081706 |
27 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.86957018 |
28 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.82905430 |
29 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.77734118 |
30 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.77122085 |
31 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.70646419 |
32 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.70266340 |
33 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.69061102 |
34 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.68134257 |
35 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.67996885 |
36 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.65787811 |
37 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 1.65588511 |
38 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.65054629 |
39 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.61784458 |
40 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.61170924 |
41 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.59587226 |
42 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.57523947 |
43 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.57092591 |
44 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.56285520 |
45 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.55608228 |
46 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.52932866 |
47 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.52737428 |
48 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.52546301 |
49 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.48294394 |
50 | * P68_20966046_ChIP-Seq_HELA_Human | 1.47503514 |
51 | * TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.46701336 |
52 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46285119 |
53 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.45445160 |
54 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.44142848 |
55 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44009821 |
56 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.43813572 |
57 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.42909145 |
58 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.42909145 |
59 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.42620383 |
60 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.42434361 |
61 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.41575379 |
62 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.40961054 |
63 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37248598 |
64 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.35048971 |
65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.30310581 |
66 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.27792171 |
67 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.27629871 |
68 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.26457972 |
69 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.26204175 |
70 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.26025775 |
71 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.25744524 |
72 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.25453020 |
73 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.24267823 |
74 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.23796506 |
75 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.23360654 |
76 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.23259004 |
77 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.23094307 |
78 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.22921422 |
79 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.22448980 |
80 | KDM2B_26808549_Chip-Seq_K562_Human | 1.21988897 |
81 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.21331289 |
82 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19391458 |
83 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.18977412 |
84 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17053002 |
85 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.16201856 |
86 | MYC_22102868_ChIP-Seq_BL_Human | 1.16037090 |
87 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.15257209 |
88 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13906590 |
89 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.12922654 |
90 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.12863252 |
91 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.12611548 |
92 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.12076497 |
93 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.11260571 |
94 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.10721154 |
95 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.10087718 |
96 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.09749520 |
97 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.09300525 |
98 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.08258406 |
99 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.07965934 |
100 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.07324226 |
101 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.07324226 |
102 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.07294728 |
103 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.05702817 |
104 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.05596119 |
105 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.04884637 |
106 | * BCOR_27268052_Chip-Seq_Bcells_Human | 1.04584785 |
107 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.04254909 |
108 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.04179483 |
109 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03567345 |
110 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03496778 |
111 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.02340391 |
112 | * SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.02031624 |
113 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.01906138 |
114 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.01824912 |
115 | * SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.01415205 |
116 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.99296316 |
117 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.98299951 |
118 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.97937645 |
119 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.97483048 |
120 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.97189395 |
121 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.96917734 |
122 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.96871935 |
123 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.96277133 |
124 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.95668315 |
125 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 0.95433463 |
126 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.95320600 |
127 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.95215011 |
128 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.94353508 |
129 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.92981753 |
130 | * JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.90566981 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010234_abnormal_vibrissa_follicle | 4.73701792 |
2 | MP0003705_abnormal_hypodermis_morpholog | 4.25841797 |
3 | MP0000566_synostosis | 3.61099487 |
4 | MP0002796_impaired_skin_barrier | 3.45184852 |
5 | MP0005275_abnormal_skin_tensile | 2.96667430 |
6 | MP0010352_gastrointestinal_tract_polyps | 2.66458761 |
7 | MP0000537_abnormal_urethra_morphology | 2.65893789 |
8 | MP0003566_abnormal_cell_adhesion | 2.60475813 |
9 | MP0004381_abnormal_hair_follicle | 2.39563332 |
10 | MP0002254_reproductive_system_inflammat | 2.31456929 |
11 | MP0005409_darkened_coat_color | 2.31175162 |
12 | MP0004264_abnormal_extraembryonic_tissu | 2.30950037 |
13 | MP0005501_abnormal_skin_physiology | 2.24377918 |
14 | MP0001849_ear_inflammation | 2.11487468 |
15 | MP0000678_abnormal_parathyroid_gland | 2.09689211 |
16 | MP0005360_urolithiasis | 2.06458706 |
17 | MP0003453_abnormal_keratinocyte_physiol | 2.04036456 |
18 | MP0004272_abnormal_basement_membrane | 2.02809253 |
19 | MP0002060_abnormal_skin_morphology | 1.95061992 |
20 | MP0000579_abnormal_nail_morphology | 1.88891217 |
21 | MP0009780_abnormal_chondrocyte_physiolo | 1.83982769 |
22 | MP0005076_abnormal_cell_differentiation | 1.81837321 |
23 | MP0003283_abnormal_digestive_organ | 1.77039453 |
24 | MP0005377_hearing/vestibular/ear_phenot | 1.76943476 |
25 | MP0003878_abnormal_ear_physiology | 1.76943476 |
26 | MP0003300_gastrointestinal_ulcer | 1.75888939 |
27 | MP0005023_abnormal_wound_healing | 1.68317808 |
28 | MP0003941_abnormal_skin_development | 1.67730542 |
29 | MP0002877_abnormal_melanocyte_morpholog | 1.65487600 |
30 | MP0010678_abnormal_skin_adnexa | 1.65241900 |
31 | MP0004185_abnormal_adipocyte_glucose | 1.64412491 |
32 | MP0001216_abnormal_epidermal_layer | 1.62720141 |
33 | MP0002139_abnormal_hepatobiliary_system | 1.58553825 |
34 | MP0005451_abnormal_body_composition | 1.55903002 |
35 | MP0005083_abnormal_biliary_tract | 1.55865360 |
36 | MP0001958_emphysema | 1.55036459 |
37 | MP0004782_abnormal_surfactant_physiolog | 1.53231260 |
38 | MP0002098_abnormal_vibrissa_morphology | 1.51285709 |
39 | MP0002249_abnormal_larynx_morphology | 1.48883338 |
40 | MP0001666_abnormal_nutrient_absorption | 1.48080659 |
41 | MP0004947_skin_inflammation | 1.45773287 |
42 | MP0008438_abnormal_cutaneous_collagen | 1.42640893 |
43 | MP0009379_abnormal_foot_pigmentation | 1.41620787 |
44 | MP0000467_abnormal_esophagus_morphology | 1.40596090 |
45 | MP0005085_abnormal_gallbladder_physiolo | 1.38556009 |
46 | MP0003191_abnormal_cellular_cholesterol | 1.36762636 |
47 | MP0003252_abnormal_bile_duct | 1.32326083 |
48 | MP0010030_abnormal_orbit_morphology | 1.24658863 |
49 | MP0005365_abnormal_bile_salt | 1.23837917 |
50 | MP0009053_abnormal_anal_canal | 1.20443978 |
51 | MP0005623_abnormal_meninges_morphology | 1.17738839 |
52 | MP0010771_integument_phenotype | 1.16819224 |
53 | MP0000762_abnormal_tongue_morphology | 1.16330592 |
54 | MP0001873_stomach_inflammation | 1.15663491 |
55 | MP0001765_abnormal_ion_homeostasis | 1.15468530 |
56 | MP0000427_abnormal_hair_cycle | 1.14348885 |
57 | MP0000377_abnormal_hair_follicle | 1.14035286 |
58 | MP0002138_abnormal_hepatobiliary_system | 1.12149547 |
59 | MP0008961_abnormal_basal_metabolism | 1.11924875 |
60 | MP0009643_abnormal_urine_homeostasis | 1.10327165 |
61 | MP0005167_abnormal_blood-brain_barrier | 1.08593343 |
62 | MP0000462_abnormal_digestive_system | 1.08094979 |
63 | MP0009840_abnormal_foam_cell | 1.07075251 |
64 | MP0002089_abnormal_postnatal_growth/wei | 1.05997926 |
65 | MP0002234_abnormal_pharynx_morphology | 1.05557329 |
66 | MP0000383_abnormal_hair_follicle | 1.04885674 |
67 | MP0008875_abnormal_xenobiotic_pharmacok | 1.04803130 |
68 | MP0001348_abnormal_lacrimal_gland | 1.02027262 |
69 | MP0000367_abnormal_coat/_hair | 1.01813094 |
70 | MP0003115_abnormal_respiratory_system | 1.00974938 |
71 | MP0010368_abnormal_lymphatic_system | 1.00562949 |
72 | MP0003045_fibrosis | 0.99705318 |
73 | MP0000534_abnormal_ureter_morphology | 0.98120590 |
74 | MP0005666_abnormal_adipose_tissue | 0.97396466 |
75 | MP0003091_abnormal_cell_migration | 0.97371696 |
76 | MP0003806_abnormal_nucleotide_metabolis | 0.95779783 |
77 | MP0001664_abnormal_digestion | 0.91439100 |
78 | MP0000477_abnormal_intestine_morphology | 0.90988190 |
79 | MP0002086_abnormal_extraembryonic_tissu | 0.89899328 |
80 | MP0009931_abnormal_skin_appearance | 0.89586523 |
81 | MP0004084_abnormal_cardiac_muscle | 0.89456079 |
82 | MP0003123_paternal_imprinting | 0.89339737 |
83 | MP0004019_abnormal_vitamin_homeostasis | 0.86893021 |
84 | MP0003119_abnormal_digestive_system | 0.86632349 |
85 | MP0002136_abnormal_kidney_physiology | 0.86254912 |
86 | MP0000733_abnormal_muscle_development | 0.86177401 |
87 | MP0006054_spinal_hemorrhage | 0.85800058 |
88 | MP0004043_abnormal_pH_regulation | 0.83351261 |
89 | MP0003183_abnormal_peptide_metabolism | 0.82413413 |
90 | MP0009384_cardiac_valve_regurgitation | 0.81496856 |
91 | MP0005367_renal/urinary_system_phenotyp | 0.80819186 |
92 | MP0000516_abnormal_urinary_system | 0.80819186 |
93 | MP0004197_abnormal_fetal_growth/weight/ | 0.80095653 |
94 | MP0005058_abnormal_lysosome_morphology | 0.80016123 |
95 | MP0001881_abnormal_mammary_gland | 0.78879183 |
96 | MP0002909_abnormal_adrenal_gland | 0.78833631 |
97 | MP0002925_abnormal_cardiovascular_devel | 0.78377859 |
98 | MP0001243_abnormal_dermal_layer | 0.78357107 |
99 | MP0000627_abnormal_mammary_gland | 0.78019664 |
100 | MP0003866_abnormal_defecation | 0.77588732 |
101 | MP0005375_adipose_tissue_phenotype | 0.77301283 |
102 | MP0003879_abnormal_hair_cell | 0.75934568 |
103 | MP0002084_abnormal_developmental_patter | 0.75826621 |
104 | MP0001346_abnormal_lacrimal_gland | 0.75417413 |
105 | MP0000647_abnormal_sebaceous_gland | 0.75182496 |
106 | MP0001191_abnormal_skin_condition | 0.75037123 |
107 | MP0010329_abnormal_lipoprotein_level | 0.74948067 |
108 | MP0002896_abnormal_bone_mineralization | 0.74840267 |
109 | MP0005332_abnormal_amino_acid | 0.74085721 |
110 | MP0001756_abnormal_urination | 0.71729390 |
111 | MP0008260_abnormal_autophagy | 0.69952658 |
112 | MP0002166_altered_tumor_susceptibility | 0.69514456 |
113 | MP0010630_abnormal_cardiac_muscle | 0.68116211 |
114 | MP0002295_abnormal_pulmonary_circulatio | 0.67660948 |
115 | MP0004858_abnormal_nervous_system | 0.66664455 |
116 | MP0000609_abnormal_liver_physiology | 0.65810529 |
117 | MP0000003_abnormal_adipose_tissue | 0.65526619 |
118 | MP0002088_abnormal_embryonic_growth/wei | 0.65334749 |
119 | MP0003984_embryonic_growth_retardation | 0.65123230 |
120 | MP0002697_abnormal_eye_size | 0.64938164 |
121 | MP0001730_embryonic_growth_arrest | 0.64875715 |
122 | MP0001672_abnormal_embryogenesis/_devel | 0.64580946 |
123 | MP0005380_embryogenesis_phenotype | 0.64580946 |
124 | MP0009278_abnormal_bone_marrow | 0.63590528 |
125 | MP0000470_abnormal_stomach_morphology | 0.63258626 |
126 | MP0001784_abnormal_fluid_regulation | 0.62931430 |
127 | MP0000858_altered_metastatic_potential | 0.62377436 |
128 | MP0010155_abnormal_intestine_physiology | 0.61649916 |
129 | MP0002085_abnormal_embryonic_tissue | 0.61309481 |
130 | MP0002111_abnormal_tail_morphology | 0.60897257 |
131 | MP0003638_abnormal_response/metabolism_ | 0.59342417 |
132 | MP0000681_abnormal_thyroid_gland | 0.59077920 |
133 | MP0009672_abnormal_birth_weight | 0.58529548 |
134 | MP0002653_abnormal_ependyma_morphology | 0.57764387 |
135 | MP0004233_abnormal_muscle_weight | 0.57599826 |
136 | MP0005670_abnormal_white_adipose | 0.56300026 |
137 | MP0005257_abnormal_intraocular_pressure | 0.54052334 |
138 | MP0002009_preneoplasia | 0.53370088 |
139 | MP0000490_abnormal_crypts_of | 0.53274168 |
140 | MP0003936_abnormal_reproductive_system | 0.53221964 |
141 | MP0005636_abnormal_mineral_homeostasis | 0.52002724 |
142 | MP0005248_abnormal_Harderian_gland | 0.51189743 |
143 | MP0006138_congestive_heart_failure | 0.49702506 |
144 | MP0005310_abnormal_salivary_gland | 0.48681242 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Right ventricular cardiomyopathy (HP:0011663) | 4.81688287 |
2 | Milia (HP:0001056) | 4.24094719 |
3 | Atrophic scars (HP:0001075) | 4.00179297 |
4 | Interstitial pulmonary disease (HP:0006530) | 3.92336795 |
5 | Onycholysis (HP:0001806) | 3.64081708 |
6 | Pili torti (HP:0003777) | 3.48185549 |
7 | Lip pit (HP:0100267) | 3.37003471 |
8 | Cerebral aneurysm (HP:0004944) | 3.30584827 |
9 | Dysmetric saccades (HP:0000641) | 3.28115680 |
10 | Plantar hyperkeratosis (HP:0007556) | 3.21037631 |
11 | Fragile nails (HP:0001808) | 3.14781665 |
12 | Chronic bronchitis (HP:0004469) | 3.10574924 |
13 | Hyperactive renin-angiotensin system (HP:0000841) | 3.07754977 |
14 | Focal segmental glomerulosclerosis (HP:0000097) | 3.01520277 |
15 | Amelogenesis imperfecta (HP:0000705) | 3.01288167 |
16 | Obstructive sleep apnea (HP:0002870) | 2.94414307 |
17 | Broad face (HP:0000283) | 2.93842274 |
18 | Shallow orbits (HP:0000586) | 2.85348374 |
19 | Septate vagina (HP:0001153) | 2.83807418 |
20 | Ulnar bowing (HP:0003031) | 2.81779282 |
21 | Woolly hair (HP:0002224) | 2.81430630 |
22 | Thick nail (HP:0001805) | 2.80676845 |
23 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.78440083 |
24 | Glomerulosclerosis (HP:0000096) | 2.77858021 |
25 | Increased connective tissue (HP:0009025) | 2.65146572 |
26 | Nail dystrophy (HP:0008404) | 2.60503404 |
27 | Esophageal varix (HP:0002040) | 2.58249063 |
28 | Gout (HP:0001997) | 2.55478797 |
29 | Germ cell neoplasia (HP:0100728) | 2.55094455 |
30 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.54813288 |
31 | Hypotrichosis (HP:0001006) | 2.53431488 |
32 | Abnormality of the dental root (HP:0006486) | 2.43460828 |
33 | Taurodontia (HP:0000679) | 2.43460828 |
34 | Abnormality of permanent molar morphology (HP:0011071) | 2.43460828 |
35 | Fragile skin (HP:0001030) | 2.42216915 |
36 | Alopecia of scalp (HP:0002293) | 2.40296926 |
37 | Aneurysm (HP:0002617) | 2.38671483 |
38 | Flat acetabular roof (HP:0003180) | 2.35503016 |
39 | Bowing of the arm (HP:0006488) | 2.35120800 |
40 | Bowed forearm bones (HP:0003956) | 2.35120800 |
41 | Hyperacusis (HP:0010780) | 2.34933662 |
42 | Protrusio acetabuli (HP:0003179) | 2.34631334 |
43 | Hand muscle atrophy (HP:0009130) | 2.34417987 |
44 | Distal upper limb amyotrophy (HP:0007149) | 2.31962805 |
45 | Upper limb amyotrophy (HP:0009129) | 2.31962805 |
46 | Abnormal hair laboratory examination (HP:0003328) | 2.31631848 |
47 | Pterygium (HP:0001059) | 2.30308525 |
48 | Malnutrition (HP:0004395) | 2.29873380 |
49 | Ridged nail (HP:0001807) | 2.29797054 |
50 | Palmoplantar hyperkeratosis (HP:0000972) | 2.29429458 |
51 | Rectal prolapse (HP:0002035) | 2.24451590 |
52 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.22677492 |
53 | Abnormality of molar (HP:0011077) | 2.22404497 |
54 | Abnormality of molar morphology (HP:0011070) | 2.22404497 |
55 | J-shaped sella turcica (HP:0002680) | 2.21859938 |
56 | Deep venous thrombosis (HP:0002625) | 2.21504355 |
57 | Bronchomalacia (HP:0002780) | 2.21264200 |
58 | Turricephaly (HP:0000262) | 2.20082852 |
59 | Lymphangioma (HP:0100764) | 2.19526527 |
60 | Ventricular tachycardia (HP:0004756) | 2.18524651 |
61 | Hyporeflexia of lower limbs (HP:0002600) | 2.18344108 |
62 | Hyperparathyroidism (HP:0000843) | 2.17905917 |
63 | Abnormality of chloride homeostasis (HP:0011422) | 2.17074483 |
64 | Selective tooth agenesis (HP:0001592) | 2.16248994 |
65 | Natal tooth (HP:0000695) | 2.16061028 |
66 | Palmar hyperkeratosis (HP:0010765) | 2.14599810 |
67 | Abnormality of the dental pulp (HP:0006479) | 2.13713461 |
68 | Broad metatarsal (HP:0001783) | 2.11908825 |
69 | Ankyloglossia (HP:0010296) | 2.10597538 |
70 | Curly hair (HP:0002212) | 2.10444288 |
71 | Abnormality of the gastric mucosa (HP:0004295) | 2.09709511 |
72 | Nasal polyposis (HP:0100582) | 2.09481408 |
73 | Premature rupture of membranes (HP:0001788) | 2.09319176 |
74 | Asymmetry of the thorax (HP:0001555) | 2.06991756 |
75 | Ankle contracture (HP:0006466) | 2.06702669 |
76 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.06466301 |
77 | Thin bony cortex (HP:0002753) | 2.02714913 |
78 | Radial bowing (HP:0002986) | 2.02193705 |
79 | Abnormality of the fingertips (HP:0001211) | 2.01933835 |
80 | Abnormal blistering of the skin (HP:0008066) | 2.01717336 |
81 | Polycythemia (HP:0001901) | 2.01605583 |
82 | Micronodular cirrhosis (HP:0001413) | 1.96970043 |
83 | Seborrheic dermatitis (HP:0001051) | 1.95984723 |
84 | Sparse eyelashes (HP:0000653) | 1.95229560 |
85 | Hematochezia (HP:0002573) | 1.94699970 |
86 | Hydroxyprolinuria (HP:0003080) | 1.94355731 |
87 | Abnormality of proline metabolism (HP:0010907) | 1.94355731 |
88 | Hyperkalemia (HP:0002153) | 1.94168352 |
89 | Cervical subluxation (HP:0003308) | 1.93683139 |
90 | Sparse scalp hair (HP:0002209) | 1.93567864 |
91 | Erythema (HP:0010783) | 1.92276695 |
92 | Back pain (HP:0003418) | 1.92038113 |
93 | Renal salt wasting (HP:0000127) | 1.91970385 |
94 | Aortic aneurysm (HP:0004942) | 1.91628510 |
95 | Stridor (HP:0010307) | 1.90928099 |
96 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.90665557 |
97 | Short humerus (HP:0005792) | 1.89860169 |
98 | Corneal erosion (HP:0200020) | 1.89495363 |
99 | Mitral valve prolapse (HP:0001634) | 1.88699922 |
100 | Shawl scrotum (HP:0000049) | 1.88578395 |
101 | Distal lower limb amyotrophy (HP:0008944) | 1.88259968 |
102 | Abnormality of nail color (HP:0100643) | 1.86584814 |
103 | Oligodontia (HP:0000677) | 1.84833934 |
104 | Spastic diplegia (HP:0001264) | 1.84301611 |
105 | Esophageal atresia (HP:0002032) | 1.83593144 |
106 | Sparse lateral eyebrow (HP:0005338) | 1.83051036 |
107 | Short nail (HP:0001799) | 1.81625699 |
108 | Visceral angiomatosis (HP:0100761) | 1.80931635 |
109 | Spinal cord compression (HP:0002176) | 1.80909007 |
110 | Biliary tract neoplasm (HP:0100574) | 1.80512172 |
111 | Hypoplasia of dental enamel (HP:0006297) | 1.80466379 |
112 | Abnormal vertebral ossification (HP:0100569) | 1.80433909 |
113 | Abdominal distention (HP:0003270) | 1.79898270 |
114 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.79532579 |
115 | Distal lower limb muscle weakness (HP:0009053) | 1.79164159 |
116 | Abnormality of the Achilles tendon (HP:0005109) | 1.78703796 |
117 | Absent eyelashes (HP:0000561) | 1.78208698 |
118 | Metaphyseal cupping (HP:0003021) | 1.77414413 |
119 | Achilles tendon contracture (HP:0001771) | 1.76526598 |
120 | Abnormality of renin-angiotensin system (HP:0000847) | 1.76204371 |
121 | Mesangial abnormality (HP:0001966) | 1.75661285 |
122 | Abnormality of the nasal mucosa (HP:0000433) | 1.75406133 |
123 | Ependymoma (HP:0002888) | 1.74692116 |
124 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.74495015 |
125 | Abnormal cartilage morphology (HP:0002763) | 1.74445692 |
126 | Progressive sensorineural hearing impairment (HP:0000408) | 1.74375825 |
127 | Popliteal pterygium (HP:0009756) | 1.73685430 |
128 | Subacute progressive viral hepatitis (HP:0006572) | 1.72902685 |
129 | Pustule (HP:0200039) | 1.72742504 |
130 | Diaphragmatic weakness (HP:0009113) | 1.72334765 |
131 | Atelectasis (HP:0100750) | 1.72238851 |
132 | Abnormality of purine metabolism (HP:0004352) | 1.72199863 |
133 | Dehydration (HP:0001944) | 1.71972308 |
134 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.71950794 |
135 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.71950794 |
136 | Neonatal death (HP:0003811) | 1.71452512 |
137 | Increased IgE level (HP:0003212) | 1.70823851 |
138 | Pseudobulbar signs (HP:0002200) | 1.70653357 |
139 | Difficulty climbing stairs (HP:0003551) | 1.69724571 |
140 | Hypoplastic labia majora (HP:0000059) | 1.69218816 |
141 | Abnormality of the salivary glands (HP:0010286) | 1.68928275 |
142 | Rhinitis (HP:0012384) | 1.68185097 |
143 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.67964797 |
144 | Absent/shortened dynein arms (HP:0200106) | 1.67964797 |
145 | Hemangiomatosis (HP:0007461) | 1.67725155 |
146 | Hamartoma of the eye (HP:0010568) | 1.66925881 |
147 | Abnormal ciliary motility (HP:0012262) | 1.66769990 |
148 | Peritonitis (HP:0002586) | 1.64991123 |
149 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.64395606 |
150 | Advanced eruption of teeth (HP:0006288) | 1.64239730 |
151 | Gastrointestinal carcinoma (HP:0002672) | 1.63486529 |
152 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.63486529 |
153 | Hemorrhage of the eye (HP:0011885) | 1.61342602 |
154 | Acanthosis nigricans (HP:0000956) | 1.60719283 |
155 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.60530584 |
156 | Xanthomatosis (HP:0000991) | 1.59852668 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 5.17791690 |
2 | ERN1 | 3.27266586 |
3 | TRIB3 | 3.23939556 |
4 | SMG1 | 3.21804781 |
5 | RIPK1 | 2.87212077 |
6 | CDK12 | 2.73534692 |
7 | LATS1 | 2.64126507 |
8 | PKN2 | 2.55012977 |
9 | PTK6 | 2.14937151 |
10 | TTN | 2.11616784 |
11 | EEF2K | 2.07827347 |
12 | PAK4 | 1.91256848 |
13 | PDGFRA | 1.84953873 |
14 | FER | 1.77761189 |
15 | RPS6KB2 | 1.75817520 |
16 | SIK1 | 1.74876712 |
17 | FGFR4 | 1.74669665 |
18 | EPHB1 | 1.74430213 |
19 | PTK2 | 1.71464940 |
20 | MST1R | 1.67221058 |
21 | LRRK2 | 1.65116876 |
22 | MAPKAPK3 | 1.63317633 |
23 | EPHB2 | 1.59327861 |
24 | STK10 | 1.53377290 |
25 | IRAK3 | 1.50380851 |
26 | TGFBR2 | 1.48567776 |
27 | NME1 | 1.47626507 |
28 | DDR2 | 1.46674095 |
29 | BMX | 1.46125632 |
30 | MAP3K10 | 1.45489704 |
31 | MET | 1.42964124 |
32 | MST4 | 1.40234212 |
33 | MAP3K3 | 1.38958172 |
34 | ICK | 1.34068704 |
35 | MAP3K2 | 1.22536282 |
36 | MTOR | 1.14055165 |
37 | MAP2K2 | 1.11571319 |
38 | MAP3K6 | 1.10412444 |
39 | MARK2 | 1.05559286 |
40 | PRPF4B | 1.04150557 |
41 | TNK2 | 1.03603640 |
42 | CDK6 | 1.00148013 |
43 | NME2 | 0.97485107 |
44 | DYRK1B | 0.96937625 |
45 | LATS2 | 0.96933443 |
46 | FRK | 0.96928409 |
47 | MAP3K7 | 0.94676491 |
48 | STK38L | 0.94331175 |
49 | NEK6 | 0.90870733 |
50 | EPHA3 | 0.88270446 |
51 | PRKCI | 0.87057855 |
52 | MUSK | 0.86939376 |
53 | PAK2 | 0.83874601 |
54 | STK3 | 0.83079528 |
55 | RPS6KA2 | 0.82880990 |
56 | LMTK2 | 0.81125392 |
57 | WNK4 | 0.80983292 |
58 | PDGFRB | 0.78973295 |
59 | FGFR1 | 0.78924011 |
60 | AKT3 | 0.75832033 |
61 | BCKDK | 0.75398119 |
62 | FLT3 | 0.75287360 |
63 | PDPK1 | 0.74597326 |
64 | MAP2K3 | 0.74129058 |
65 | TYRO3 | 0.73320806 |
66 | NEK1 | 0.72934861 |
67 | GRK6 | 0.72206047 |
68 | ALK | 0.70910121 |
69 | MATK | 0.69738863 |
70 | TESK1 | 0.69457857 |
71 | TIE1 | 0.69447534 |
72 | CSK | 0.69212318 |
73 | CAMK1D | 0.68814984 |
74 | PRKG2 | 0.68359411 |
75 | TRPM7 | 0.68048719 |
76 | ERBB4 | 0.67014847 |
77 | FGFR2 | 0.66472599 |
78 | GSK3A | 0.65951303 |
79 | TAOK1 | 0.64512012 |
80 | TAOK3 | 0.63853476 |
81 | MAP2K1 | 0.63228432 |
82 | DMPK | 0.63168997 |
83 | MAP3K8 | 0.62460524 |
84 | OXSR1 | 0.60225355 |
85 | STK38 | 0.59292272 |
86 | HIPK2 | 0.59146404 |
87 | PAK3 | 0.57028400 |
88 | CHUK | 0.55130346 |
89 | IRAK2 | 0.52759542 |
90 | ERBB2 | 0.52618156 |
91 | STK39 | 0.51733861 |
92 | NEK2 | 0.51581286 |
93 | FGFR3 | 0.50960101 |
94 | SCYL2 | 0.50924831 |
95 | PRKD1 | 0.50231094 |
96 | WNK1 | 0.49980786 |
97 | MAP2K6 | 0.48687146 |
98 | STK24 | 0.47256136 |
99 | CDK7 | 0.45945486 |
100 | CAMK1G | 0.45015827 |
101 | MAP3K9 | 0.44480343 |
102 | KSR2 | 0.44440119 |
103 | PRKAA2 | 0.44350007 |
104 | RET | 0.44029347 |
105 | MAP3K1 | 0.43952681 |
106 | TTK | 0.43887294 |
107 | TGFBR1 | 0.42679154 |
108 | PIK3CA | 0.42597634 |
109 | AKT2 | 0.41435874 |
110 | EGFR | 0.41368311 |
111 | RPS6KL1 | 0.41004966 |
112 | RPS6KC1 | 0.41004966 |
113 | TESK2 | 0.39691649 |
114 | PRKD2 | 0.38309587 |
115 | CDK4 | 0.35358593 |
116 | NTRK1 | 0.34159639 |
117 | CDC42BPA | 0.34158856 |
118 | MAPK15 | 0.33421313 |
119 | PIM2 | 0.32905533 |
120 | RPS6KA1 | 0.32780909 |
121 | MAPK11 | 0.32004910 |
122 | DAPK3 | 0.31592850 |
123 | JAK2 | 0.30152636 |
124 | PRKD3 | 0.29475282 |
125 | RPS6KB1 | 0.28575284 |
126 | MAPKAPK2 | 0.28444343 |
127 | ARAF | 0.27347761 |
128 | RPS6KA6 | 0.26596933 |
129 | SIK3 | 0.25820455 |
130 | MAPK8 | 0.25294649 |
131 | TBK1 | 0.23623408 |
132 | CDK9 | 0.22346403 |
133 | ILK | 0.21834553 |
134 | MELK | 0.21174658 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.36777884 |
2 | Adherens junction_Homo sapiens_hsa04520 | 2.02200172 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.01972669 |
4 | Bladder cancer_Homo sapiens_hsa05219 | 1.98764799 |
5 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.90444299 |
6 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.87724080 |
7 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.76503118 |
8 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.72992171 |
9 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.70393970 |
10 | Focal adhesion_Homo sapiens_hsa04510 | 1.68890974 |
11 | Tight junction_Homo sapiens_hsa04530 | 1.67624299 |
12 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.66391946 |
13 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.60341775 |
14 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.59516841 |
15 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.58975040 |
16 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.58734551 |
17 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.55451368 |
18 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.54166021 |
19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.53363508 |
20 | Bile secretion_Homo sapiens_hsa04976 | 1.52014460 |
21 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.51881398 |
22 | Lysine degradation_Homo sapiens_hsa00310 | 1.51195288 |
23 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.50560034 |
24 | Amoebiasis_Homo sapiens_hsa05146 | 1.50451453 |
25 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.49707973 |
26 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.49664166 |
27 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.47743369 |
28 | Other glycan degradation_Homo sapiens_hsa00511 | 1.46535885 |
29 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.29429024 |
30 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.28874265 |
31 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.28337211 |
32 | Mineral absorption_Homo sapiens_hsa04978 | 1.27561107 |
33 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.24399620 |
34 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.24046327 |
35 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.22859289 |
36 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.22564112 |
37 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.22237973 |
38 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.21917878 |
39 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.21775745 |
40 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.20269894 |
41 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.19098965 |
42 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.19060213 |
43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18267407 |
44 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.11075270 |
45 | Thyroid cancer_Homo sapiens_hsa05216 | 1.07971410 |
46 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.04719969 |
47 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.04551238 |
48 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 1.04289606 |
49 | Insulin resistance_Homo sapiens_hsa04931 | 1.03396398 |
50 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.02251261 |
51 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.02057963 |
52 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.01744695 |
53 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.01202585 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.00059097 |
55 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.97937406 |
56 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.97515924 |
57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.94599941 |
58 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.93431588 |
59 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.92639086 |
60 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.92053569 |
61 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.90280222 |
62 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.90011873 |
63 | ABC transporters_Homo sapiens_hsa02010 | 0.89578200 |
64 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.89572884 |
65 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.89556488 |
66 | Carbon metabolism_Homo sapiens_hsa01200 | 0.88539108 |
67 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.88271799 |
68 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.86992526 |
69 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.86867684 |
70 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.86857232 |
71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.86759304 |
72 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.85193976 |
73 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.84994384 |
74 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.84387726 |
75 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.83164427 |
76 | Endometrial cancer_Homo sapiens_hsa05213 | 0.82630549 |
77 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.82484567 |
78 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.82313200 |
79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.82275036 |
80 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.81017503 |
81 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.79065730 |
82 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.78705548 |
83 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.78252617 |
84 | Axon guidance_Homo sapiens_hsa04360 | 0.77132850 |
85 | Histidine metabolism_Homo sapiens_hsa00340 | 0.76018660 |
86 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.75892062 |
87 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.74506383 |
88 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.74220240 |
89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.74166299 |
90 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.73960519 |
91 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.72841350 |
92 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.72619189 |
93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72549541 |
94 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.71002562 |
95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.71000221 |
96 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.70041034 |
97 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.69947224 |
98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.69825077 |
99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.69460322 |
100 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.69374915 |
101 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.68717240 |
102 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.68412106 |
103 | Pathways in cancer_Homo sapiens_hsa05200 | 0.68168725 |
104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.67809678 |
105 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.67728051 |
106 | Endocytosis_Homo sapiens_hsa04144 | 0.66474727 |
107 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.66270057 |
108 | Galactose metabolism_Homo sapiens_hsa00052 | 0.66195063 |
109 | Melanogenesis_Homo sapiens_hsa04916 | 0.65447928 |
110 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64078219 |
111 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.63230846 |
112 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.62259899 |
113 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.61908227 |
114 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.60674539 |
115 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.60082723 |
116 | Glioma_Homo sapiens_hsa05214 | 0.59846959 |
117 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59521851 |
118 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.59489672 |
119 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.58979075 |
120 | Retinol metabolism_Homo sapiens_hsa00830 | 0.58702452 |
121 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.56913075 |
122 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55673299 |
123 | Apoptosis_Homo sapiens_hsa04210 | 0.54421951 |
124 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.54005014 |
125 | Hepatitis C_Homo sapiens_hsa05160 | 0.53132941 |
126 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.52763952 |
127 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.52242046 |
128 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.52214703 |
129 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.52100968 |
130 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.51907674 |
131 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.51210475 |
132 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.49990409 |
133 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.48290857 |
134 | Viral myocarditis_Homo sapiens_hsa05416 | 0.47902631 |
135 | Prostate cancer_Homo sapiens_hsa05215 | 0.46392529 |
136 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.44797688 |