

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of chronic inflammatory response (GO:0002676) | 8.19135539 |
| 2 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.88684190 |
| 3 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 5.58986630 |
| 4 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 4.70723840 |
| 5 | alpha-beta T cell activation involved in immune response (GO:0002287) | 4.70723840 |
| 6 | T cell differentiation involved in immune response (GO:0002292) | 4.70723840 |
| 7 | rRNA modification (GO:0000154) | 4.66990984 |
| 8 | rRNA methylation (GO:0031167) | 4.60749332 |
| 9 | regulation of podosome assembly (GO:0071801) | 4.46539318 |
| 10 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.44392226 |
| 11 | regulation of MHC class II biosynthetic process (GO:0045346) | 4.35225815 |
| 12 | positive regulation of B cell mediated immunity (GO:0002714) | 4.29128614 |
| 13 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 4.29128614 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.25658619 |
| 15 | positive regulation of humoral immune response (GO:0002922) | 4.21476073 |
| 16 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.12279578 |
| 17 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.10306143 |
| 18 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.02200413 |
| 19 | positive regulation of isotype switching (GO:0045830) | 4.01920754 |
| 20 | positive regulation of DNA recombination (GO:0045911) | 3.98573386 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.97692038 |
| 22 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.90665938 |
| 23 | T-helper cell differentiation (GO:0042093) | 3.90665938 |
| 24 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.87573608 |
| 25 | proteasome assembly (GO:0043248) | 3.83787391 |
| 26 | alpha-beta T cell differentiation (GO:0046632) | 3.77150050 |
| 27 | cellular ketone body metabolic process (GO:0046950) | 3.70484181 |
| 28 | regulation of immunoglobulin secretion (GO:0051023) | 3.63845901 |
| 29 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.63384697 |
| 30 | DNA deamination (GO:0045006) | 3.60732605 |
| 31 | respiratory chain complex IV assembly (GO:0008535) | 3.60419677 |
| 32 | termination of RNA polymerase III transcription (GO:0006386) | 3.59379835 |
| 33 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.59379835 |
| 34 | regulation of growth of symbiont in host (GO:0044126) | 3.54080108 |
| 35 | negative regulation of growth of symbiont in host (GO:0044130) | 3.54080108 |
| 36 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.54080108 |
| 37 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.54080108 |
| 38 | ATP synthesis coupled proton transport (GO:0015986) | 3.50184262 |
| 39 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.50184262 |
| 40 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.47718134 |
| 41 | positive regulation of immunoglobulin production (GO:0002639) | 3.40392653 |
| 42 | somite rostral/caudal axis specification (GO:0032525) | 3.40039286 |
| 43 | pseudouridine synthesis (GO:0001522) | 3.38716408 |
| 44 | negative regulation of acute inflammatory response (GO:0002674) | 3.37331340 |
| 45 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.36696673 |
| 46 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.36696673 |
| 47 | signal peptide processing (GO:0006465) | 3.34222170 |
| 48 | protein neddylation (GO:0045116) | 3.33383535 |
| 49 | maturation of 5.8S rRNA (GO:0000460) | 3.31019443 |
| 50 | alpha-beta T cell activation (GO:0046631) | 3.30540504 |
| 51 | lymph node development (GO:0048535) | 3.27033148 |
| 52 | ketone body metabolic process (GO:1902224) | 3.25748519 |
| 53 | negative regulation of neurological system process (GO:0031645) | 3.24236477 |
| 54 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.18569455 |
| 55 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.17321703 |
| 56 | activated T cell proliferation (GO:0050798) | 3.11183462 |
| 57 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.10716359 |
| 58 | protein complex biogenesis (GO:0070271) | 3.07758713 |
| 59 | cellular response to interleukin-15 (GO:0071350) | 3.05924173 |
| 60 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.04375928 |
| 61 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.03418174 |
| 62 | defense response to protozoan (GO:0042832) | 3.01255537 |
| 63 | CTP metabolic process (GO:0046036) | 3.01143314 |
| 64 | CTP biosynthetic process (GO:0006241) | 3.01143314 |
| 65 | cytochrome complex assembly (GO:0017004) | 2.99265150 |
| 66 | GTP biosynthetic process (GO:0006183) | 2.98797855 |
| 67 | L-fucose metabolic process (GO:0042354) | 2.97797430 |
| 68 | L-fucose catabolic process (GO:0042355) | 2.97797430 |
| 69 | fucose catabolic process (GO:0019317) | 2.97797430 |
| 70 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.97321049 |
| 71 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.97321049 |
| 72 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.97321049 |
| 73 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.95662093 |
| 74 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.95662093 |
| 75 | positive regulation of granulocyte differentiation (GO:0030854) | 2.95065095 |
| 76 | DNA double-strand break processing (GO:0000729) | 2.93663433 |
| 77 | interferon-gamma production (GO:0032609) | 2.92180360 |
| 78 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.91214029 |
| 79 | positive regulation of organelle assembly (GO:1902117) | 2.90512289 |
| 80 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.90049404 |
| 81 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 2.89910308 |
| 82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.89653964 |
| 83 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.89585596 |
| 84 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.88252165 |
| 85 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.87010131 |
| 86 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.85834403 |
| 87 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.85834403 |
| 88 | isotype switching (GO:0045190) | 2.85834403 |
| 89 | tRNA processing (GO:0008033) | 2.84743183 |
| 90 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.84278262 |
| 91 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.83981071 |
| 92 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.83981071 |
| 93 | cytokine biosynthetic process (GO:0042089) | 2.83444772 |
| 94 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.83184558 |
| 95 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.82579111 |
| 96 | cytidine deamination (GO:0009972) | 2.82573861 |
| 97 | cytidine metabolic process (GO:0046087) | 2.82573861 |
| 98 | cytidine catabolic process (GO:0006216) | 2.82573861 |
| 99 | adenosine metabolic process (GO:0046085) | 2.80785386 |
| 100 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.79504210 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.27428390 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.99650144 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.98262666 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.46948807 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.24275889 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.05775519 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.91946798 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.84134218 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.64752968 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.64686010 |
| 11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.55078715 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.43160965 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.41526109 |
| 14 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.26391150 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.23663498 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.23572979 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.18810271 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.15840383 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.01177196 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.95018868 |
| 21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.95016256 |
| 22 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.93532715 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.92651988 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.86603155 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.81659931 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.78613779 |
| 27 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.76465482 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.64739014 |
| 29 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.63739465 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.61988885 |
| 31 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.60364117 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.56165644 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.54628377 |
| 34 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52799255 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.49278582 |
| 36 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.46603613 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.45821976 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.45566569 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.45209853 |
| 40 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.43114711 |
| 41 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.39657655 |
| 42 | FUS_26573619_Chip-Seq_HEK293_Human | 1.38832851 |
| 43 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.38239917 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.37053439 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.33834850 |
| 46 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.33566955 |
| 47 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32221693 |
| 48 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.31947167 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.30827276 |
| 50 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.30255244 |
| 51 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.28624006 |
| 52 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28389602 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26175464 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26175464 |
| 55 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.24814791 |
| 56 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.24584760 |
| 57 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.23567169 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.23264817 |
| 59 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.23264817 |
| 60 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.21063680 |
| 61 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.20896839 |
| 62 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.20734701 |
| 63 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.17185836 |
| 64 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.13889937 |
| 65 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.12534093 |
| 66 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.12359168 |
| 67 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.10600268 |
| 68 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.09398633 |
| 69 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07972354 |
| 70 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.06488955 |
| 71 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05993912 |
| 72 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.04335539 |
| 73 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.04139759 |
| 74 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.03482628 |
| 75 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.03330813 |
| 76 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03047728 |
| 77 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.02043697 |
| 78 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.01780441 |
| 79 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01497502 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98658254 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97128432 |
| 82 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.97079345 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.96985297 |
| 84 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96384855 |
| 85 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.96134988 |
| 86 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95869038 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95739752 |
| 88 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95558699 |
| 89 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.95257516 |
| 90 | MYB_26560356_Chip-Seq_TH2_Human | 0.95106896 |
| 91 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.94889673 |
| 92 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94541524 |
| 93 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.94463339 |
| 94 | NCOR_22424771_ChIP-Seq_293T_Human | 0.94454095 |
| 95 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94369333 |
| 96 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94082454 |
| 97 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.93761673 |
| 98 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.93629767 |
| 99 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92988461 |
| 100 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.92901533 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001873_stomach_inflammation | 4.58577040 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.72024245 |
| 3 | MP0005671_abnormal_response_to | 3.50226968 |
| 4 | MP0000685_abnormal_immune_system | 3.35438542 |
| 5 | MP0001348_abnormal_lacrimal_gland | 3.02009253 |
| 6 | MP0002254_reproductive_system_inflammat | 2.97165550 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.87795197 |
| 8 | MP0005645_abnormal_hypothalamus_physiol | 2.84266535 |
| 9 | MP0005387_immune_system_phenotype | 2.83183601 |
| 10 | MP0001790_abnormal_immune_system | 2.83183601 |
| 11 | MP0009785_altered_susceptibility_to | 2.73962159 |
| 12 | MP0001501_abnormal_sleep_pattern | 2.39587783 |
| 13 | MP0010386_abnormal_urinary_bladder | 2.39370986 |
| 14 | MP0009333_abnormal_splenocyte_physiolog | 2.31549841 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.24495864 |
| 16 | MP0002166_altered_tumor_susceptibility | 2.22806540 |
| 17 | MP0008872_abnormal_physiological_respon | 2.21764602 |
| 18 | MP0003436_decreased_susceptibility_to | 2.10750058 |
| 19 | MP0005310_abnormal_salivary_gland | 2.10086262 |
| 20 | MP0002006_tumorigenesis | 2.09617618 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.98678235 |
| 22 | MP0002138_abnormal_hepatobiliary_system | 1.98321740 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.88637512 |
| 24 | MP0005379_endocrine/exocrine_gland_phen | 1.83015737 |
| 25 | MP0003646_muscle_fatigue | 1.82797410 |
| 26 | MP0008058_abnormal_DNA_repair | 1.82435131 |
| 27 | MP0001800_abnormal_humoral_immune | 1.67533123 |
| 28 | MP0004142_abnormal_muscle_tone | 1.66050506 |
| 29 | MP0003186_abnormal_redox_activity | 1.61591149 |
| 30 | MP0000372_irregular_coat_pigmentation | 1.61319652 |
| 31 | MP0002163_abnormal_gland_morphology | 1.59881167 |
| 32 | MP0005000_abnormal_immune_tolerance | 1.57169947 |
| 33 | MP0002693_abnormal_pancreas_physiology | 1.55295662 |
| 34 | MP0003195_calcinosis | 1.54267268 |
| 35 | MP0002102_abnormal_ear_morphology | 1.51882821 |
| 36 | MP0008057_abnormal_DNA_replication | 1.42404253 |
| 37 | MP0005075_abnormal_melanosome_morpholog | 1.40963048 |
| 38 | MP0002139_abnormal_hepatobiliary_system | 1.39119843 |
| 39 | MP0002837_dystrophic_cardiac_calcinosis | 1.39030524 |
| 40 | MP0003763_abnormal_thymus_physiology | 1.38115894 |
| 41 | MP0006072_abnormal_retinal_apoptosis | 1.29944524 |
| 42 | MP0002405_respiratory_system_inflammati | 1.24701484 |
| 43 | MP0005646_abnormal_pituitary_gland | 1.22878223 |
| 44 | MP0006082_CNS_inflammation | 1.22151306 |
| 45 | MP0001944_abnormal_pancreas_morphology | 1.17497758 |
| 46 | MP0000427_abnormal_hair_cycle | 1.15492271 |
| 47 | MP0009764_decreased_sensitivity_to | 1.15457022 |
| 48 | MP0002723_abnormal_immune_serum | 1.14516944 |
| 49 | MP0005085_abnormal_gallbladder_physiolo | 1.10702763 |
| 50 | MP0004043_abnormal_pH_regulation | 1.05870510 |
| 51 | MP0005025_abnormal_response_to | 1.05678917 |
| 52 | MP0003866_abnormal_defecation | 1.05135640 |
| 53 | MP0002272_abnormal_nervous_system | 1.03922205 |
| 54 | MP0005083_abnormal_biliary_tract | 1.02724717 |
| 55 | MP0003283_abnormal_digestive_organ | 1.02465616 |
| 56 | MP0010155_abnormal_intestine_physiology | 0.98278336 |
| 57 | MP0001845_abnormal_inflammatory_respons | 0.94391021 |
| 58 | MP0005165_increased_susceptibility_to | 0.93623111 |
| 59 | MP0001663_abnormal_digestive_system | 0.92529807 |
| 60 | MP0003786_premature_aging | 0.91526670 |
| 61 | MP0002420_abnormal_adaptive_immunity | 0.90168528 |
| 62 | MP0001819_abnormal_immune_cell | 0.89156055 |
| 63 | MP0001984_abnormal_olfaction | 0.87612517 |
| 64 | MP0005636_abnormal_mineral_homeostasis | 0.87015297 |
| 65 | MP0004885_abnormal_endolymph | 0.86846653 |
| 66 | MP0002452_abnormal_antigen_presenting | 0.86262260 |
| 67 | MP0001905_abnormal_dopamine_level | 0.85149005 |
| 68 | MP0001970_abnormal_pain_threshold | 0.83984114 |
| 69 | MP0001764_abnormal_homeostasis | 0.83389078 |
| 70 | MP0004145_abnormal_muscle_electrophysio | 0.83224549 |
| 71 | MP0005448_abnormal_energy_balance | 0.82170140 |
| 72 | MP0001666_abnormal_nutrient_absorption | 0.81661559 |
| 73 | MP0004147_increased_porphyrin_level | 0.81297743 |
| 74 | MP0005389_reproductive_system_phenotype | 0.80457793 |
| 75 | MP0005551_abnormal_eye_electrophysiolog | 0.80271508 |
| 76 | MP0001919_abnormal_reproductive_system | 0.80104279 |
| 77 | MP0002638_abnormal_pupillary_reflex | 0.79562254 |
| 78 | MP0003806_abnormal_nucleotide_metabolis | 0.79359599 |
| 79 | MP0004215_abnormal_myocardial_fiber | 0.79006859 |
| 80 | MP0002938_white_spotting | 0.77285411 |
| 81 | MP0000689_abnormal_spleen_morphology | 0.76930418 |
| 82 | MP0004133_heterotaxia | 0.76622366 |
| 83 | MP0006036_abnormal_mitochondrial_physio | 0.76550194 |
| 84 | MP0002933_joint_inflammation | 0.76502423 |
| 85 | MP0002876_abnormal_thyroid_physiology | 0.76190633 |
| 86 | MP0002909_abnormal_adrenal_gland | 0.74802933 |
| 87 | MP0001968_abnormal_touch/_nociception | 0.74645763 |
| 88 | MP0003936_abnormal_reproductive_system | 0.73779018 |
| 89 | MP0002733_abnormal_thermal_nociception | 0.73709701 |
| 90 | MP0001881_abnormal_mammary_gland | 0.73177666 |
| 91 | MP0005332_abnormal_amino_acid | 0.73083941 |
| 92 | MP0005381_digestive/alimentary_phenotyp | 0.72802596 |
| 93 | MP0009745_abnormal_behavioral_response | 0.71157957 |
| 94 | MP0005365_abnormal_bile_salt | 0.70803541 |
| 95 | MP0004957_abnormal_blastocyst_morpholog | 0.69677573 |
| 96 | MP0008995_early_reproductive_senescence | 0.68796884 |
| 97 | MP0005220_abnormal_exocrine_pancreas | 0.68726900 |
| 98 | MP0002736_abnormal_nociception_after | 0.68483134 |
| 99 | MP0001756_abnormal_urination | 0.67181672 |
| 100 | MP0000703_abnormal_thymus_morphology | 0.66215671 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 5.64547941 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.96753269 |
| 3 | Acute encephalopathy (HP:0006846) | 4.46990610 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 4.35089383 |
| 5 | Increased CSF lactate (HP:0002490) | 4.34390486 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.31544484 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 4.21691872 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.03639262 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.92876486 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.66997935 |
| 11 | Renal Fanconi syndrome (HP:0001994) | 3.62097656 |
| 12 | IgG deficiency (HP:0004315) | 3.48345201 |
| 13 | Methylmalonic aciduria (HP:0012120) | 3.13791995 |
| 14 | Cerebral edema (HP:0002181) | 3.04398559 |
| 15 | Increased serum lactate (HP:0002151) | 3.03099890 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.02016525 |
| 17 | Large for gestational age (HP:0001520) | 3.01297888 |
| 18 | Hepatocellular necrosis (HP:0001404) | 2.99538246 |
| 19 | Abnormality of vitamin B metabolism (HP:0004340) | 2.95397393 |
| 20 | Abnormality of the renal cortex (HP:0011035) | 2.94689511 |
| 21 | Renal cortical cysts (HP:0000803) | 2.88553543 |
| 22 | Abnormality of methionine metabolism (HP:0010901) | 2.86176642 |
| 23 | Optic disc pallor (HP:0000543) | 2.84297951 |
| 24 | Exertional dyspnea (HP:0002875) | 2.83027744 |
| 25 | Hepatic necrosis (HP:0002605) | 2.82572292 |
| 26 | Abnormal albumin level (HP:0012116) | 2.71729526 |
| 27 | Hypoalbuminemia (HP:0003073) | 2.71729526 |
| 28 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.64639742 |
| 29 | Congenital stationary night blindness (HP:0007642) | 2.62996258 |
| 30 | Hypoproteinemia (HP:0003075) | 2.55149158 |
| 31 | Lethargy (HP:0001254) | 2.48879244 |
| 32 | Abnormality of the pons (HP:0007361) | 2.48542102 |
| 33 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.44860283 |
| 34 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.43462092 |
| 35 | Hypoplasia of the pons (HP:0012110) | 2.41917655 |
| 36 | Respiratory failure (HP:0002878) | 2.38333633 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.37652558 |
| 38 | Tongue fasciculations (HP:0001308) | 2.36815099 |
| 39 | Abnormality of urine glucose concentration (HP:0011016) | 2.33873670 |
| 40 | Glycosuria (HP:0003076) | 2.33873670 |
| 41 | Aplastic anemia (HP:0001915) | 2.33231486 |
| 42 | Pancreatic cysts (HP:0001737) | 2.33213210 |
| 43 | Chronic diarrhea (HP:0002028) | 2.32770901 |
| 44 | Hyperalaninemia (HP:0003348) | 2.31677143 |
| 45 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.31677143 |
| 46 | Abnormality of alanine metabolism (HP:0010916) | 2.31677143 |
| 47 | Ketoacidosis (HP:0001993) | 2.30323154 |
| 48 | Hypothermia (HP:0002045) | 2.30257711 |
| 49 | Nephronophthisis (HP:0000090) | 2.29384295 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.23930415 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.23930415 |
| 52 | Lactic acidosis (HP:0003128) | 2.22899166 |
| 53 | Respiratory difficulties (HP:0002880) | 2.19242631 |
| 54 | Abnormality of renal resorption (HP:0011038) | 2.16567149 |
| 55 | Hyperphosphaturia (HP:0003109) | 2.11784384 |
| 56 | Leukodystrophy (HP:0002415) | 2.10316056 |
| 57 | Tubular atrophy (HP:0000092) | 2.10126574 |
| 58 | Increased IgM level (HP:0003496) | 2.09523255 |
| 59 | Abnormal biliary tract physiology (HP:0012439) | 2.07913175 |
| 60 | Bile duct proliferation (HP:0001408) | 2.07913175 |
| 61 | Abnormality of macular pigmentation (HP:0008002) | 2.07370327 |
| 62 | Acute hepatic failure (HP:0006554) | 2.07359388 |
| 63 | Exercise intolerance (HP:0003546) | 2.06697256 |
| 64 | Mesangial abnormality (HP:0001966) | 2.06572444 |
| 65 | Abnormality of vitamin metabolism (HP:0100508) | 2.05964847 |
| 66 | Limb hypertonia (HP:0002509) | 2.05558634 |
| 67 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.05191635 |
| 68 | Dicarboxylic aciduria (HP:0003215) | 2.05191635 |
| 69 | Microvesicular hepatic steatosis (HP:0001414) | 2.03764609 |
| 70 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.03348566 |
| 71 | Abolished electroretinogram (ERG) (HP:0000550) | 2.00143836 |
| 72 | Abnormality of the renal medulla (HP:0100957) | 2.00043921 |
| 73 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.99077036 |
| 74 | T lymphocytopenia (HP:0005403) | 1.98773378 |
| 75 | Cheilitis (HP:0100825) | 1.97981679 |
| 76 | Colon cancer (HP:0003003) | 1.97779738 |
| 77 | Abnormality of T cells (HP:0002843) | 1.95591406 |
| 78 | Muscular hypotonia of the trunk (HP:0008936) | 1.93731497 |
| 79 | Palpitations (HP:0001962) | 1.93270335 |
| 80 | Increased intramyocellular lipid droplets (HP:0012240) | 1.92870364 |
| 81 | Pancytopenia (HP:0001876) | 1.91879403 |
| 82 | IgA deficiency (HP:0002720) | 1.91703488 |
| 83 | Recurrent cutaneous fungal infections (HP:0011370) | 1.90291072 |
| 84 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.90291072 |
| 85 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.90289014 |
| 86 | Muscle fibrillation (HP:0010546) | 1.90264797 |
| 87 | Proximal tubulopathy (HP:0000114) | 1.89943492 |
| 88 | Gonadotropin excess (HP:0000837) | 1.89187007 |
| 89 | Type II lissencephaly (HP:0007260) | 1.86811890 |
| 90 | Abnormality of the fovea (HP:0000493) | 1.86377297 |
| 91 | Paralysis (HP:0003470) | 1.83878296 |
| 92 | Abnormality of T cell physiology (HP:0011840) | 1.83281980 |
| 93 | Abnormal pupillary function (HP:0007686) | 1.81861303 |
| 94 | X-linked dominant inheritance (HP:0001423) | 1.81340227 |
| 95 | Homocystinuria (HP:0002156) | 1.81035536 |
| 96 | Abnormality of homocysteine metabolism (HP:0010919) | 1.81035536 |
| 97 | Abnormality of T cell number (HP:0011839) | 1.80837746 |
| 98 | Abnormal drinking behavior (HP:0030082) | 1.78564457 |
| 99 | Polydipsia (HP:0001959) | 1.78564457 |
| 100 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.77990043 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.63187165 |
| 2 | MST4 | 4.55796153 |
| 3 | EIF2AK3 | 3.21651197 |
| 4 | TXK | 3.11091746 |
| 5 | VRK2 | 3.03496726 |
| 6 | NUAK1 | 2.76400541 |
| 7 | ADRBK2 | 2.72101923 |
| 8 | MAP3K12 | 2.69530630 |
| 9 | FRK | 2.53153531 |
| 10 | TRIM28 | 2.42631776 |
| 11 | NME1 | 2.26149527 |
| 12 | PBK | 2.13205416 |
| 13 | WNK4 | 1.95927358 |
| 14 | EIF2AK1 | 1.86262605 |
| 15 | GRK1 | 1.86068865 |
| 16 | MAP4K2 | 1.83927393 |
| 17 | VRK1 | 1.71028068 |
| 18 | ZAK | 1.64635779 |
| 19 | BMPR1B | 1.63258886 |
| 20 | NEK1 | 1.54007166 |
| 21 | MAP3K9 | 1.52262642 |
| 22 | PLK3 | 1.51601422 |
| 23 | SIK3 | 1.47129023 |
| 24 | TNIK | 1.46026569 |
| 25 | TESK1 | 1.41032481 |
| 26 | PINK1 | 1.39310763 |
| 27 | STK39 | 1.36906510 |
| 28 | TEC | 1.31484744 |
| 29 | TLK1 | 1.30104383 |
| 30 | MYLK | 1.26545966 |
| 31 | MAP2K6 | 1.25721951 |
| 32 | NLK | 1.21295443 |
| 33 | OXSR1 | 1.19076266 |
| 34 | MAPKAPK3 | 1.18835731 |
| 35 | SRPK1 | 1.17546502 |
| 36 | ACVR1B | 1.14836825 |
| 37 | STK3 | 1.09628550 |
| 38 | ITK | 1.09449383 |
| 39 | CSNK1G1 | 1.09054770 |
| 40 | DAPK1 | 1.05914128 |
| 41 | WNK3 | 1.05634669 |
| 42 | STK24 | 1.01431498 |
| 43 | TNK2 | 0.98446561 |
| 44 | PHKG2 | 0.95402091 |
| 45 | PHKG1 | 0.95402091 |
| 46 | CLK1 | 0.94360365 |
| 47 | CSNK1G3 | 0.88995391 |
| 48 | STK16 | 0.84441704 |
| 49 | STK4 | 0.84055514 |
| 50 | EIF2AK2 | 0.84000095 |
| 51 | TGFBR1 | 0.82486825 |
| 52 | MUSK | 0.80515195 |
| 53 | IKBKB | 0.77714378 |
| 54 | TAF1 | 0.76402966 |
| 55 | PLK2 | 0.76063740 |
| 56 | PAK3 | 0.75069942 |
| 57 | PASK | 0.75049842 |
| 58 | DAPK2 | 0.71559567 |
| 59 | MAP3K4 | 0.66649050 |
| 60 | STK38L | 0.64143884 |
| 61 | TAOK3 | 0.63897339 |
| 62 | ERBB3 | 0.63265032 |
| 63 | CASK | 0.63165274 |
| 64 | CSNK1A1L | 0.61850644 |
| 65 | CSNK1G2 | 0.59983830 |
| 66 | TRPM7 | 0.58668627 |
| 67 | ALK | 0.57650208 |
| 68 | PIK3CG | 0.57441324 |
| 69 | PRKCE | 0.56309404 |
| 70 | ADRBK1 | 0.54422026 |
| 71 | TIE1 | 0.53611104 |
| 72 | LATS1 | 0.53025550 |
| 73 | BUB1 | 0.50157828 |
| 74 | WNK1 | 0.49288895 |
| 75 | INSRR | 0.44555897 |
| 76 | MKNK2 | 0.42362250 |
| 77 | PRKCG | 0.41329281 |
| 78 | CAMK2A | 0.39337918 |
| 79 | ILK | 0.38005414 |
| 80 | CAMK2D | 0.36324912 |
| 81 | PRKG1 | 0.36038425 |
| 82 | PDK2 | 0.35940359 |
| 83 | MAP4K1 | 0.35847319 |
| 84 | FGFR1 | 0.33995110 |
| 85 | BCR | 0.29895042 |
| 86 | KDR | 0.27332997 |
| 87 | PAK4 | 0.26805839 |
| 88 | CSNK1A1 | 0.26111631 |
| 89 | PRKCQ | 0.25416507 |
| 90 | IKBKE | 0.24829701 |
| 91 | CSNK2A2 | 0.24666857 |
| 92 | PLK4 | 0.24397065 |
| 93 | PRKCA | 0.23108798 |
| 94 | RPS6KA5 | 0.22665289 |
| 95 | DAPK3 | 0.20955237 |
| 96 | GSK3A | 0.20804520 |
| 97 | FLT3 | 0.19847254 |
| 98 | PRKCB | 0.19700725 |
| 99 | PRKACA | 0.19618312 |
| 100 | LCK | 0.19373283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.12470411 |
| 2 | Protein export_Homo sapiens_hsa03060 | 4.46395831 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.78452765 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.72537501 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.65284925 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.58055359 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.56840018 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.51779378 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.32770904 |
| 10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.20099439 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.06668440 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.02563609 |
| 13 | RNA degradation_Homo sapiens_hsa03018 | 1.97300854 |
| 14 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.96853346 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.96374599 |
| 16 | Parkinsons disease_Homo sapiens_hsa05012 | 1.92231771 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.91019996 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.76822600 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.64866502 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.63287315 |
| 21 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.60566574 |
| 22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.59827799 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.44604116 |
| 24 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.40970018 |
| 25 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.40773779 |
| 26 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.39788201 |
| 27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.38329842 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.37285752 |
| 29 | RNA transport_Homo sapiens_hsa03013 | 1.28895343 |
| 30 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.28564743 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.27993921 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.24210139 |
| 33 | Alzheimers disease_Homo sapiens_hsa05010 | 1.24115285 |
| 34 | Huntingtons disease_Homo sapiens_hsa05016 | 1.23664766 |
| 35 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.19948942 |
| 36 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.19377372 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.19077077 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.16594829 |
| 39 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12547335 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 1.12382953 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.10373001 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.09402189 |
| 43 | Measles_Homo sapiens_hsa05162 | 1.05349378 |
| 44 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.04193331 |
| 45 | Mismatch repair_Homo sapiens_hsa03430 | 1.04189392 |
| 46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.01111970 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89847406 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82066250 |
| 49 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.81489326 |
| 50 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.81382286 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.81134521 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.80072474 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.77149862 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.72626828 |
| 55 | Homologous recombination_Homo sapiens_hsa03440 | 0.71899184 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.69805468 |
| 57 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69575246 |
| 58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.68306502 |
| 59 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.67242864 |
| 60 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66493789 |
| 61 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.65751288 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.64886678 |
| 63 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.64304587 |
| 64 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.63000066 |
| 65 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62359273 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.61037593 |
| 67 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.60389820 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.58958245 |
| 69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.58780755 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55508391 |
| 71 | Ribosome_Homo sapiens_hsa03010 | 0.53541422 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53369837 |
| 73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.51255330 |
| 74 | Spliceosome_Homo sapiens_hsa03040 | 0.48705698 |
| 75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.43468413 |
| 76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.43074770 |
| 77 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42297780 |
| 78 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.39709276 |
| 79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.39282415 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37111044 |
| 81 | Circadian rhythm_Homo sapiens_hsa04710 | 0.35225225 |
| 82 | Insulin secretion_Homo sapiens_hsa04911 | 0.34645599 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.34102637 |
| 84 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.32449046 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30840710 |
| 86 | ABC transporters_Homo sapiens_hsa02010 | 0.30490189 |
| 87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.30060860 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30057030 |
| 89 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.30032856 |
| 90 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.29859745 |
| 91 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29288007 |
| 92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.27851057 |
| 93 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.27831528 |
| 94 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.23692359 |
| 95 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.21853235 |
| 96 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20175214 |
| 97 | Morphine addiction_Homo sapiens_hsa05032 | 0.18898289 |
| 98 | Malaria_Homo sapiens_hsa05144 | 0.18362029 |
| 99 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18206344 |
| 100 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.18151424 |

