CDCA3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1polyketide metabolic process (GO:0030638)8.61872701
2doxorubicin metabolic process (GO:0044598)8.61872701
3daunorubicin metabolic process (GO:0044597)8.61872701
4protein localization to kinetochore (GO:0034501)7.14145206
5mitotic sister chromatid segregation (GO:0000070)6.02875707
6regulation of spindle organization (GO:0090224)5.90012859
7negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)5.82994378
8regulation of nuclear cell cycle DNA replication (GO:0033262)5.81146668
9protein localization to chromosome, centromeric region (GO:0071459)5.73667102
10regulation of telomere maintenance via telomerase (GO:0032210)5.67748631
11regulation of mitotic spindle organization (GO:0060236)5.62409460
12metaphase plate congression (GO:0051310)5.59901017
13negative regulation of epidermis development (GO:0045683)5.52500477
14kinetochore organization (GO:0051383)5.50681034
15aminoglycoside antibiotic metabolic process (GO:0030647)5.50309723
16maintenance of protein location in nucleus (GO:0051457)5.46674189
17regulation of mammary gland epithelial cell proliferation (GO:0033599)5.42342276
18negative regulation of cell cycle G2/M phase transition (GO:1902750)5.33932439
19negative regulation of telomerase activity (GO:0051974)5.32159696
20sister chromatid segregation (GO:0000819)5.18630494
21DNA replication-dependent nucleosome organization (GO:0034723)5.16277655
22DNA replication-dependent nucleosome assembly (GO:0006335)5.16277655
23CENP-A containing nucleosome assembly (GO:0034080)5.09488382
24somite rostral/caudal axis specification (GO:0032525)5.03948821
25kinetochore assembly (GO:0051382)4.97913496
26chromatin remodeling at centromere (GO:0031055)4.95992940
27DNA replication checkpoint (GO:0000076)4.94962291
28regulation of response to osmotic stress (GO:0047484)4.88599614
29rRNA transcription (GO:0009303)4.79835442
30establishment of chromosome localization (GO:0051303)4.77547767
31heterochromatin organization (GO:0070828)4.77334509
32histone H4-K12 acetylation (GO:0043983)4.74292393
33histone H4-K8 acetylation (GO:0043982)4.73547925
34histone H4-K5 acetylation (GO:0043981)4.73547925
35negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)4.68612027
36spindle checkpoint (GO:0031577)4.67703207
37DNA ligation (GO:0006266)4.60478063
38DNA topological change (GO:0006265)4.59421725
39DNA strand elongation involved in DNA replication (GO:0006271)4.58443206
40nuclear pore complex assembly (GO:0051292)4.56803854
41regulation of chromosome segregation (GO:0051983)4.50258322
42negative regulation of epidermal cell differentiation (GO:0045605)4.49428955
43DNA strand elongation (GO:0022616)4.45997042
44positive regulation of DNA-dependent DNA replication (GO:2000105)4.45326251
45chromosome segregation (GO:0007059)4.42347902
46negative regulation of chromosome segregation (GO:0051985)4.39701916
47microtubule depolymerization (GO:0007019)4.34628196
48rRNA methylation (GO:0031167)4.33999109
49negative regulation of telomere maintenance (GO:0032205)4.33650598
50telomere maintenance via semi-conservative replication (GO:0032201)4.32504309
51muscle organ morphogenesis (GO:0048644)4.31085887
52mitotic spindle checkpoint (GO:0071174)4.29744845
53notochord development (GO:0030903)4.29168697
54rRNA modification (GO:0000154)4.27692160
55mitotic chromosome condensation (GO:0007076)4.27131797
56negative regulation of mitotic metaphase/anaphase transition (GO:0045841)4.25384332
57negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)4.25384332
58negative regulation of mitotic sister chromatid segregation (GO:0033048)4.25384332
59negative regulation of mitotic sister chromatid separation (GO:2000816)4.25384332
60negative regulation of sister chromatid segregation (GO:0033046)4.25384332
61nuclear pore organization (GO:0006999)4.24380104
62chromatin assembly (GO:0031497)4.24183067
63mitotic spindle assembly checkpoint (GO:0007094)4.20905276
64positive regulation of chromosome segregation (GO:0051984)4.19513759
65spindle assembly checkpoint (GO:0071173)4.16969097
66regulation of translation in response to stress (GO:0043555)4.14659590
67regulation of MHC class I biosynthetic process (GO:0045343)4.09334614
68histone exchange (GO:0043486)4.06422789
69regulation of mitotic sister chromatid separation (GO:0010965)4.00362021
70regulation of mitotic sister chromatid segregation (GO:0033047)4.00362021
71regulation of sister chromatid segregation (GO:0033045)4.00362021
72meiotic chromosome segregation (GO:0045132)4.00295302
73regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.98961773
74regulation of mitotic metaphase/anaphase transition (GO:0030071)3.98961773
75regulation of cilium movement (GO:0003352)3.96533150
76DNA replication-independent nucleosome organization (GO:0034724)3.95063754
77DNA replication-independent nucleosome assembly (GO:0006336)3.95063754
78anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.93790586
79positive regulation of mitotic sister chromatid separation (GO:1901970)3.86113598
80positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.86113598
81positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.86113598
82protein K6-linked ubiquitination (GO:0085020)3.82960081
83mitotic recombination (GO:0006312)3.80152699
84regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.78726394
85DNA unwinding involved in DNA replication (GO:0006268)3.77274215
86establishment of integrated proviral latency (GO:0075713)3.76881713
87cytidine metabolic process (GO:0046087)3.76738794
88cytidine catabolic process (GO:0006216)3.76738794
89cytidine deamination (GO:0009972)3.76738794
90formation of translation preinitiation complex (GO:0001731)3.76064564
91DNA packaging (GO:0006323)3.72281753
92telomere maintenance via recombination (GO:0000722)3.65565091
93regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.62427982
94cullin deneddylation (GO:0010388)3.60524439
95DNA duplex unwinding (GO:0032508)3.55866649
96ribosome biogenesis (GO:0042254)3.55488097
97DNA geometric change (GO:0032392)3.52465556
98regulation of apoptotic process involved in morphogenesis (GO:1902337)3.52131455
99histone H4-K16 acetylation (GO:0043984)3.51203327
100negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.49498079
101regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.48822006
102DNA replication initiation (GO:0006270)3.48701779
103negative regulation of mitosis (GO:0045839)3.46183510
104pore complex assembly (GO:0046931)3.45907919
105primitive streak formation (GO:0090009)3.43461061
106pre-miRNA processing (GO:0031054)3.37274777
107ventricular cardiac muscle cell development (GO:0055015)3.36898599
108interferon-gamma production (GO:0032609)3.36872683
109DNA damage response, detection of DNA damage (GO:0042769)3.36272826
110regulation of centrosome cycle (GO:0046605)3.35589730
111regulation of telomerase activity (GO:0051972)3.34762743
112positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.34456889
113cell fate commitment involved in formation of primary germ layer (GO:0060795)3.33252691
114mitotic cell cycle (GO:0000278)3.33193308
115regulation of telomere maintenance (GO:0032204)3.32936632
116RNA stabilization (GO:0043489)3.31999542
117mRNA stabilization (GO:0048255)3.31999542
118nucleoside transmembrane transport (GO:1901642)3.31784007
119quinone metabolic process (GO:1901661)3.28350717
120hormone catabolic process (GO:0042447)3.26681177
121branching involved in mammary gland duct morphogenesis (GO:0060444)3.25715646
122protein deneddylation (GO:0000338)3.25601514
123nucleotide-excision repair, DNA gap filling (GO:0006297)3.24878117
124negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.23138467
125negative regulation of ligase activity (GO:0051352)3.23138467
126proteasome assembly (GO:0043248)3.22390710
127chromosome condensation (GO:0030261)3.22322317
128pseudouridine synthesis (GO:0001522)3.21881041
129protein localization to chromosome (GO:0034502)3.20795845
130phenol-containing compound catabolic process (GO:0019336)3.20409489
131regulation of double-strand break repair (GO:2000779)3.20040636
132mitotic metaphase plate congression (GO:0007080)3.19460832
133attachment of spindle microtubules to kinetochore (GO:0008608)3.19160691
134regulation of sister chromatid cohesion (GO:0007063)3.17862044
135intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771)3.16513177
136mitotic nuclear envelope disassembly (GO:0007077)3.15879877
137establishment of viral latency (GO:0019043)3.13812036
138intestinal epithelial cell development (GO:0060576)3.12817241
139ribosomal small subunit biogenesis (GO:0042274)3.11767713
140spindle assembly (GO:0051225)3.11439638
141regulation of centriole replication (GO:0046599)3.11402378
142DNA strand renaturation (GO:0000733)3.11291667
143regulation of posttranscriptional gene silencing (GO:0060147)3.10595202
144regulation of gene silencing by miRNA (GO:0060964)3.10595202
145regulation of gene silencing by RNA (GO:0060966)3.10595202
146ATP-dependent chromatin remodeling (GO:0043044)3.10533705
147mitotic G2/M transition checkpoint (GO:0044818)3.10417553
148regulation of DNA-dependent DNA replication (GO:0090329)3.09714752
149regulation of mitochondrial translation (GO:0070129)3.08626370
150histone-serine phosphorylation (GO:0035404)3.07591681
151chromatin assembly or disassembly (GO:0006333)3.07399676
152mitotic sister chromatid cohesion (GO:0007064)3.03901999
153apoptotic DNA fragmentation (GO:0006309)3.03202543
154negative regulation of cell division (GO:0051782)3.01743717
155nuclear envelope organization (GO:0006998)3.01550917
156trophectodermal cell differentiation (GO:0001829)3.00718887
157DNA conformation change (GO:0071103)3.00712996
158maintenance of protein localization in organelle (GO:0072595)3.00634812
159telomere maintenance via telomere lengthening (GO:0010833)2.99749257
160microtubule polymerization or depolymerization (GO:0031109)2.98744956
161replication fork processing (GO:0031297)2.97265828
162transcription from mitochondrial promoter (GO:0006390)2.96661276
163negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)2.95498539
164response to dietary excess (GO:0002021)2.94348760
165positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.94283258
166* mitotic nuclear division (GO:0007067)2.94028647
167positive regulation of protein deacetylation (GO:0090312)2.93436549
168establishment of mitotic spindle localization (GO:0040001)2.93289436
169chromosome organization (GO:0051276)2.93151608
170regulation of spindle checkpoint (GO:0090231)2.93113161
171negative regulation of nuclear division (GO:0051784)2.92367887
172ribonucleoprotein complex biogenesis (GO:0022613)2.92296037
173spindle assembly involved in mitosis (GO:0090307)2.92148436
174resolution of meiotic recombination intermediates (GO:0000712)2.90922161
175membrane disassembly (GO:0030397)2.90074983
176nuclear envelope disassembly (GO:0051081)2.90074983
177regulation of ubiquitin-protein transferase activity (GO:0051438)2.89725856
178GDP-mannose metabolic process (GO:0019673)2.89173934
179maternal placenta development (GO:0001893)2.88028093
180regulation of double-strand break repair via homologous recombination (GO:0010569)2.87466414

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.82665751
2KLF2_18264089_ChIP-ChIP_MESCs_Mouse4.99734452
3KLF5_18264089_ChIP-ChIP_MESCs_Mouse4.99734452
4KLF4_18264089_ChIP-ChIP_MESCs_Mouse4.99734452
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.49455948
6FOXM1_23109430_ChIP-Seq_U2OS_Human4.06641354
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.00250917
8* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.41619365
9* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.86994238
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.81464957
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.78619176
12SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.57603539
13POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.55831422
14* MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.54639862
15* NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.50290453
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.37361062
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.27708997
18* SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.11986158
19TCF3_18692474_ChIP-Seq_MEFs_Mouse2.10571459
20* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.08120270
21TCF3_18692474_ChIP-Seq_MESCs_Mouse2.05907280
22NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.00961868
23KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.98430003
24ELK1_19687146_ChIP-ChIP_HELA_Human1.92868850
25* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91903862
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.88562667
27TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.88537502
28CREB1_15753290_ChIP-ChIP_HEK293T_Human1.88127181
29NANOG_18555785_ChIP-Seq_MESCs_Mouse1.87937301
30* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82555074
31* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.82256710
32STAT3_1855785_ChIP-Seq_MESCs_Mouse1.80917684
33POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.79409511
34KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.73317203
35SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.73149491
36* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.72570435
37EST1_17652178_ChIP-ChIP_JURKAT_Human1.70868170
38* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.69768455
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.63563195
40PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.61751373
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.60115946
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.59560257
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.58377783
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.57826897
45* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.57659781
46ELF1_17652178_ChIP-ChIP_JURKAT_Human1.56127650
47* NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.53582328
48SOX2_18555785_ChIP-Seq_MESCs_Mouse1.51466134
49SRF_21415370_ChIP-Seq_HL-1_Mouse1.51444598
50MYC_22102868_ChIP-Seq_BL_Human1.51420844
51IRF1_19129219_ChIP-ChIP_H3396_Human1.51015786
52* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.48078768
53AR_21909140_ChIP-Seq_LNCAP_Human1.47743247
54RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47470347
55HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46996711
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.43081423
57SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.41845035
58ETS1_20019798_ChIP-Seq_JURKAT_Human1.37428251
59POU5F1_16518401_ChIP-PET_MESCs_Mouse1.37354362
60JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.37239747
61XRN2_22483619_ChIP-Seq_HELA_Human1.36250844
62ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.35476586
63HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35294581
64KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33778410
65TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.32496588
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.31858428
67E2F1_18555785_ChIP-Seq_MESCs_Mouse1.30568365
68POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.29959729
69FOXP3_21729870_ChIP-Seq_TREG_Human1.28164537
70NELFA_20434984_ChIP-Seq_ESCs_Mouse1.27635905
71OCT4_18692474_ChIP-Seq_MEFs_Mouse1.25744992
72* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24994864
73* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.23322180
74MYC_18940864_ChIP-ChIP_HL60_Human1.21000091
75* TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.18916032
76GABP_17652178_ChIP-ChIP_JURKAT_Human1.18045971
77* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.17133247
78ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.15940816
79SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13501720
80MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13494717
81* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.12800828
82NANOG_21062744_ChIP-ChIP_HESCs_Human1.12479062
83* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.11791793
84KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07803474
85KDM5A_27292631_Chip-Seq_BREAST_Human1.06543010
86KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06470935
87EGR1_19374776_ChIP-ChIP_THP-1_Human1.06204567
88TTF2_22483619_ChIP-Seq_HELA_Human1.06104199
89NANOG_16153702_ChIP-ChIP_HESCs_Human1.05165680
90ERG_20887958_ChIP-Seq_HPC-7_Mouse1.03294867
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.02802481
92* E2F1_17053090_ChIP-ChIP_MCF-7_Human1.02391851
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01564848
94TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.01483682
95NOTCH1_21737748_ChIP-Seq_TLL_Human1.01075243
96E2F1_21310950_ChIP-Seq_MCF-7_Human1.00953994
97PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.99041537
98* GABP_19822575_ChIP-Seq_HepG2_Human0.98329127
99* VDR_23849224_ChIP-Seq_CD4+_Human0.97398598
100CIITA_25753668_ChIP-Seq_RAJI_Human0.96149464
101PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.95212874
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94985614
103SOX2_16153702_ChIP-ChIP_HESCs_Human0.93641499
104HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93478323
105ZFX_18555785_ChIP-Seq_MESCs_Mouse0.91822451
106ZFP281_18757296_ChIP-ChIP_E14_Mouse0.91413667
107BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89736638
108CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89188938
109NCOR1_26117541_ChIP-Seq_K562_Human0.88845947
110* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88793435
111DCP1A_22483619_ChIP-Seq_HELA_Human0.88153345
112CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.87844801
113* NANOG_16518401_ChIP-PET_MESCs_Mouse0.87003578
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84430533
115SALL1_21062744_ChIP-ChIP_HESCs_Human0.84392025
116SOX17_20123909_ChIP-Seq_XEN_Mouse0.84005114
117HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.82495757
118SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.82464468
119* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.82426901
120TP53_22127205_ChIP-Seq_IMR90_Human0.82282368
121CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.81592975
122YY1_22570637_ChIP-Seq_MALME-3M_Human0.77350150
123TCF7_22412390_ChIP-Seq_EML_Mouse0.76809645
124ESR1_15608294_ChIP-ChIP_MCF-7_Human0.76561533
125ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.76177226
126KAP1_27257070_Chip-Seq_ESCs_Mouse0.75119964
127POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.74438807
128SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.74032796
129CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.73736697
130* THAP11_20581084_ChIP-Seq_MESCs_Mouse0.73633311
131* HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.73595628
132* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.73034705
133* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.69673375
134HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.68641438
135* FOXP1_21924763_ChIP-Seq_HESCs_Human0.68608818
136TBX5_21415370_ChIP-Seq_HL-1_Mouse0.68370372
137* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.67990530
138CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.67523380
139SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.67009049
140TFEB_21752829_ChIP-Seq_HELA_Human0.65407127
141POU5F1_16153702_ChIP-ChIP_HESCs_Human0.62811471
142ZNF263_19887448_ChIP-Seq_K562_Human0.62531671

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.84786414
2MP0003011_delayed_dark_adaptation3.83863673
3MP0004957_abnormal_blastocyst_morpholog3.82594876
4MP0004264_abnormal_extraembryonic_tissu3.77791079
5MP0008057_abnormal_DNA_replication3.73469350
6MP0002254_reproductive_system_inflammat3.35504823
7MP0003890_abnormal_embryonic-extraembry3.25265175
8MP0005394_taste/olfaction_phenotype2.75951643
9MP0005499_abnormal_olfactory_system2.75951643
10MP0003111_abnormal_nucleus_morphology2.72080229
11MP0005075_abnormal_melanosome_morpholog2.70153438
12MP0003077_abnormal_cell_cycle2.62410611
13MP0003718_maternal_effect2.53086705
14MP0003693_abnormal_embryo_hatching2.50322084
15MP0010094_abnormal_chromosome_stability2.45669829
16MP0003122_maternal_imprinting2.38690460
17MP0010352_gastrointestinal_tract_polyps2.30578755
18MP0003121_genomic_imprinting2.28566208
19MP0004858_abnormal_nervous_system2.26344633
20MP0003705_abnormal_hypodermis_morpholog2.22022780
21MP0002653_abnormal_ependyma_morphology2.18086805
22MP0005257_abnormal_intraocular_pressure2.16584947
23MP0005380_embryogenesis_phenotype2.11735183
24MP0001672_abnormal_embryogenesis/_devel2.11735183
25MP0002332_abnormal_exercise_endurance2.09421856
26MP0003123_paternal_imprinting2.05894489
27MP0003806_abnormal_nucleotide_metabolis2.04803848
28MP0009697_abnormal_copulation2.03947930
29MP0006035_abnormal_mitochondrial_morpho2.01918178
30MP0000350_abnormal_cell_proliferation1.94017307
31MP0002088_abnormal_embryonic_growth/wei1.92577389
32MP0003984_embryonic_growth_retardation1.92304157
33MP0010030_abnormal_orbit_morphology1.82690364
34MP0003938_abnormal_ear_development1.72922864
35MP0000678_abnormal_parathyroid_gland1.68979202
36MP0002938_white_spotting1.65172589
37MP0008932_abnormal_embryonic_tissue1.64929110
38MP0001293_anophthalmia1.63974916
39MP0002396_abnormal_hematopoietic_system1.62122227
40MP0002085_abnormal_embryonic_tissue1.56173533
41MP0001730_embryonic_growth_arrest1.54861711
42MP0008007_abnormal_cellular_replicative1.54079945
43MP0002086_abnormal_extraembryonic_tissu1.52891208
44MP0010307_abnormal_tumor_latency1.51332932
45MP0000372_irregular_coat_pigmentation1.47134671
46MP0001849_ear_inflammation1.42464516
47MP0002127_abnormal_cardiovascular_syste1.39826950
48MP0002277_abnormal_respiratory_mucosa1.39093910
49MP0003950_abnormal_plasma_membrane1.38485999
50MP0002084_abnormal_developmental_patter1.36483824
51MP0000490_abnormal_crypts_of1.36029647
52MP0002092_abnormal_eye_morphology1.34928173
53MP0002932_abnormal_joint_morphology1.33398177
54MP0001697_abnormal_embryo_size1.30627119
55MP0001929_abnormal_gametogenesis1.29969407
56MP0001346_abnormal_lacrimal_gland1.29276524
57MP0001529_abnormal_vocalization1.28223372
58MP0003315_abnormal_perineum_morphology1.27039618
59MP0000049_abnormal_middle_ear1.26338077
60MP0008058_abnormal_DNA_repair1.25229921
61MP0000313_abnormal_cell_death1.24696801
62MP0008789_abnormal_olfactory_epithelium1.23107550
63MP0004197_abnormal_fetal_growth/weight/1.23104762
64MP0002080_prenatal_lethality1.19586621
65MP0000762_abnormal_tongue_morphology1.16818345
66MP0008961_abnormal_basal_metabolism1.15323196
67MP0003119_abnormal_digestive_system1.15287538
68MP0005266_abnormal_metabolism1.12168878
69MP0003183_abnormal_peptide_metabolism1.09992243
70MP0000428_abnormal_craniofacial_morphol1.08317175
71MP0004133_heterotaxia1.05284724
72MP0002114_abnormal_axial_skeleton1.04291266
73MP0000653_abnormal_sex_gland1.03484180
74MP0002233_abnormal_nose_morphology1.03256360
75MP0003786_premature_aging1.02049972
76MP0000432_abnormal_head_morphology1.00637560
77MP0003186_abnormal_redox_activity0.99487128
78MP0002697_abnormal_eye_size0.98938089
79MP0006036_abnormal_mitochondrial_physio0.98860623
80MP0002234_abnormal_pharynx_morphology0.97801183
81MP0006082_CNS_inflammation0.97400789
82MP0002160_abnormal_reproductive_system0.96087210
83MP0003935_abnormal_craniofacial_develop0.93954542
84MP0002877_abnormal_melanocyte_morpholog0.93741993
85MP0005171_absent_coat_pigmentation0.93613633
86MP0002163_abnormal_gland_morphology0.93541365
87MP0004147_increased_porphyrin_level0.92462905
88MP0002132_abnormal_respiratory_system0.92337477
89MP0008770_decreased_survivor_rate0.92241838
90MP0002970_abnormal_white_adipose0.90607493
91MP0003755_abnormal_palate_morphology0.90476302
92MP0008877_abnormal_DNA_methylation0.88565878
93MP0000537_abnormal_urethra_morphology0.87455822
94MP0003567_abnormal_fetal_cardiomyocyte0.87090712
95MP0002019_abnormal_tumor_incidence0.86934198
96MP0003698_abnormal_male_reproductive0.86630562
97MP0003136_yellow_coat_color0.84565555
98MP0009672_abnormal_birth_weight0.83141133
99MP0005408_hypopigmentation0.82156131
100MP0000358_abnormal_cell_content/0.81189037
101MP0001119_abnormal_female_reproductive0.80286846
102MP0003283_abnormal_digestive_organ0.80100477
103MP0000566_synostosis0.79728151
104MP0001727_abnormal_embryo_implantation0.79685008
105MP0009703_decreased_birth_body0.79573348
106MP0003937_abnormal_limbs/digits/tail_de0.79336013
107MP0002925_abnormal_cardiovascular_devel0.78823025
108MP0005391_vision/eye_phenotype0.78087633
109MP0002161_abnormal_fertility/fecundity0.77369218
110MP0005023_abnormal_wound_healing0.75967275
111MP0004381_abnormal_hair_follicle0.75800263
112MP0005395_other_phenotype0.74881342
113MP0001764_abnormal_homeostasis0.74821380
114MP0003787_abnormal_imprinting0.74307428
115MP0003699_abnormal_female_reproductive0.73915024
116MP0001286_abnormal_eye_development0.73332286
117MP0000750_abnormal_muscle_regeneration0.72899332
118MP0001145_abnormal_male_reproductive0.72011510
119MP0009250_abnormal_appendicular_skeleto0.71836899
120MP0002249_abnormal_larynx_morphology0.71107289
121MP0000647_abnormal_sebaceous_gland0.70896663
122MP0002111_abnormal_tail_morphology0.70358058
123MP0001348_abnormal_lacrimal_gland0.69867115
124MP0002095_abnormal_skin_pigmentation0.69857176
125MP0005248_abnormal_Harderian_gland0.69220979
126MP0002116_abnormal_craniofacial_bone0.68669035
127MP0005384_cellular_phenotype0.67623228
128MP0005508_abnormal_skeleton_morphology0.67068569
129MP0002751_abnormal_autonomic_nervous0.66514548
130MP0009379_abnormal_foot_pigmentation0.66158698
131MP0003385_abnormal_body_wall0.66135403
132MP0006072_abnormal_retinal_apoptosis0.65252441
133MP0003942_abnormal_urinary_system0.64145171
134MP0002102_abnormal_ear_morphology0.62107906
135MP0005389_reproductive_system_phenotype0.61995125
136MP0002177_abnormal_outer_ear0.61972612
137MP0002269_muscular_atrophy0.61295855
138MP0008995_early_reproductive_senescence0.59716240
139MP0000858_altered_metastatic_potential0.59680512
140MP0004043_abnormal_pH_regulation0.59679441
141MP0002098_abnormal_vibrissa_morphology0.59481702
142MP0005076_abnormal_cell_differentiation0.57846296
143MP0003941_abnormal_skin_development0.57515112
144MP0005501_abnormal_skin_physiology0.57204667
145MP0003943_abnormal_hepatobiliary_system0.57030020
146MP0003861_abnormal_nervous_system0.56160288
147MP0003137_abnormal_impulse_conducting0.56040671
148MP0002210_abnormal_sex_determination0.55269098
149MP0000631_abnormal_neuroendocrine_gland0.55197839
150MP0002081_perinatal_lethality0.55038762

Predicted human phenotypes

RankGene SetZ-score
1Bilateral microphthalmos (HP:0007633)6.89344795
2Hypochromic microcytic anemia (HP:0004840)5.73069413
3Multiple enchondromatosis (HP:0005701)5.22959872
4Hepatoblastoma (HP:0002884)4.81318665
5Ependymoma (HP:0002888)4.43597054
6Rib fusion (HP:0000902)4.38569786
7Chromosomal breakage induced by crosslinking agents (HP:0003221)4.37555946
8Abnormality of the lower motor neuron (HP:0002366)4.21525706
9Nephroblastoma (Wilms tumor) (HP:0002667)3.96056747
10Chromsome breakage (HP:0040012)3.90786404
11Rhabdomyosarcoma (HP:0002859)3.88054094
12Neoplasm of striated muscle (HP:0009728)3.84603464
13Embryonal renal neoplasm (HP:0011794)3.67651584
14Birth length less than 3rd percentile (HP:0003561)3.40329669
15Abnormal lung lobation (HP:0002101)3.33796885
16Reticulocytopenia (HP:0001896)3.26856639
17Increased nuchal translucency (HP:0010880)3.14101062
18Fused cervical vertebrae (HP:0002949)3.13997155
19Meckel diverticulum (HP:0002245)3.13719645
20Trismus (HP:0000211)3.13248603
21Testicular atrophy (HP:0000029)3.11809924
22Abnormality of the astrocytes (HP:0100707)3.06258552
23Astrocytoma (HP:0009592)3.06258552
24Aplasia/Hypoplasia of the fovea (HP:0008060)3.04314628
25Hypoplasia of the fovea (HP:0007750)3.04314628
26Rectal fistula (HP:0100590)3.03826242
27Rectovaginal fistula (HP:0000143)3.03826242
28Impulsivity (HP:0100710)2.97159238
29Partial duplication of thumb phalanx (HP:0009944)2.95393978
30Aplasia/hypoplasia of the humerus (HP:0006507)2.94408253
31Abnormality of the ileum (HP:0001549)2.94252159
32Patellar aplasia (HP:0006443)2.87781332
33Breast hypoplasia (HP:0003187)2.86359768
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.86061764
35Ectopic kidney (HP:0000086)2.84016563
36Amyotrophic lateral sclerosis (HP:0007354)2.80878964
37Ragged-red muscle fibers (HP:0003200)2.80171476
38Abnormality of the salivary glands (HP:0010286)2.79928599
39Hypoplastic pelvis (HP:0008839)2.77908779
40Short humerus (HP:0005792)2.77887218
41Hypoplasia of the capital femoral epiphysis (HP:0003090)2.76843436
42Bifid tongue (HP:0010297)2.72768746
43Horseshoe kidney (HP:0000085)2.72064908
44Aplasia/Hypoplasia of the patella (HP:0006498)2.70158333
45Intestinal fistula (HP:0100819)2.69094781
46Abnormality of the carotid arteries (HP:0005344)2.68846122
47Cortical dysplasia (HP:0002539)2.67759479
48Absent radius (HP:0003974)2.67440746
49Supernumerary spleens (HP:0009799)2.64401553
50Broad distal phalanx of finger (HP:0009836)2.63120222
51Partial duplication of the phalanx of hand (HP:0009999)2.61928372
52Hypochromic anemia (HP:0001931)2.61607071
53Preauricular skin tag (HP:0000384)2.61442629
54Acute necrotizing encephalopathy (HP:0006965)2.61399019
55Abnormal mitochondria in muscle tissue (HP:0008316)2.58947019
56Abnormal cartilage morphology (HP:0002763)2.55820952
57Squamous cell carcinoma (HP:0002860)2.55407945
58Vaginal fistula (HP:0004320)2.55139727
59Reduced antithrombin III activity (HP:0001976)2.54270783
60Duodenal stenosis (HP:0100867)2.54244712
61Small intestinal stenosis (HP:0012848)2.54244712
62Absent forearm bone (HP:0003953)2.53416056
63Aplasia involving forearm bones (HP:0009822)2.53416056
64Abnormal number of incisors (HP:0011064)2.50703462
65Acute encephalopathy (HP:0006846)2.46662610
66Shawl scrotum (HP:0000049)2.40752499
67Abnormality of chromosome segregation (HP:0002916)2.40487201
68Absent thumb (HP:0009777)2.39995808
69Triphalangeal thumb (HP:0001199)2.38648845
70Medulloblastoma (HP:0002885)2.37949161
71Aplasia/Hypoplasia of the sternum (HP:0006714)2.36568309
72Anomalous pulmonary venous return (HP:0010772)2.36531050
73Glioma (HP:0009733)2.36427570
74Hyperinsulinemic hypoglycemia (HP:0000825)2.34490823
75Clubbing of toes (HP:0100760)2.34412978
76Carpal bone hypoplasia (HP:0001498)2.33822436
77Duplicated collecting system (HP:0000081)2.33532830
78Progressive muscle weakness (HP:0003323)2.32989143
79Skin tags (HP:0010609)2.32171346
80Horizontal nystagmus (HP:0000666)2.29474071
81Abnormality of glycolysis (HP:0004366)2.29177889
82Microretrognathia (HP:0000308)2.28739162
83Large earlobe (HP:0009748)2.28048554
84Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.25151922
85Absent epiphyses (HP:0010577)2.25151922
86Glossoptosis (HP:0000162)2.24913058
87Abnormality of the fovea (HP:0000493)2.23503406
88Mitochondrial inheritance (HP:0001427)2.23325113
89Pendular nystagmus (HP:0012043)2.21691369
90Abnormality of the preputium (HP:0100587)2.21681502
91Increased CSF lactate (HP:0002490)2.20135939
92Renal duplication (HP:0000075)2.19899810
93Preauricular pit (HP:0004467)2.19285992
94Periauricular skin pits (HP:0100277)2.19285992
95Abnormality of the phalanges of the hallux (HP:0010057)2.19104023
96Short thumb (HP:0009778)2.18997483
97Premature ovarian failure (HP:0008209)2.18967533
98Volvulus (HP:0002580)2.18540325
99Atresia of the external auditory canal (HP:0000413)2.18469132
100Abnormal umbilical cord blood vessels (HP:0011403)2.16647657
101Single umbilical artery (HP:0001195)2.16647657
102Abnormality of the fetal cardiovascular system (HP:0010948)2.16647657
103Abnormality of DNA repair (HP:0003254)2.15828978
104Short 5th finger (HP:0009237)2.15497005
105Hypoplasia of the pons (HP:0012110)2.13976503
106Type I transferrin isoform profile (HP:0003642)2.13950485
107Tongue fasciculations (HP:0001308)2.12868193
108Atrophy/Degeneration involving motor neurons (HP:0007373)2.12669557
109Hepatocellular necrosis (HP:0001404)2.10927954
110Increased serum pyruvate (HP:0003542)2.10862495
111Abnormal number of erythroid precursors (HP:0012131)2.10568376
112Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.10330403
113Abnormality of the renal collecting system (HP:0004742)2.08942525
114Generalized hypotonia (HP:0001290)2.08715492
115Aplastic anemia (HP:0001915)2.07552113
116Abnormality of cells of the erythroid lineage (HP:0012130)2.06764680
117Nasolacrimal duct obstruction (HP:0000579)2.06672320
118Abnormality of the duodenum (HP:0002246)2.06186888
119Abnormality of the pons (HP:0007361)2.05481647
120Combined immunodeficiency (HP:0005387)2.05044441
121Microvesicular hepatic steatosis (HP:0001414)2.04339913
122Abnormality of the labia minora (HP:0012880)2.03712614
123Myelodysplasia (HP:0002863)2.03615386
124Abnormality of small intestinal villus morphology (HP:0011472)2.02373513
125Villous atrophy (HP:0011473)2.02373513
126Sloping forehead (HP:0000340)2.01933074
127Malignant neoplasm of the central nervous system (HP:0100836)2.01838610
128Aplasia/Hypoplasia of the macula (HP:0008059)2.01110649
129Abnormality of the pulmonary veins (HP:0011718)2.00226197
130Facial cleft (HP:0002006)1.99939430
131Selective tooth agenesis (HP:0001592)1.99101497
132Hypopigmentation of the fundus (HP:0007894)1.98099617
133Aplasia/Hypoplasia of the sacrum (HP:0008517)1.98028825
134Embryonal neoplasm (HP:0002898)1.97933614
135Poikiloderma (HP:0001029)1.95723645
136Facial hemangioma (HP:0000329)1.95322058
137Abnormality of chromosome stability (HP:0003220)1.94948466
138Sensory axonal neuropathy (HP:0003390)1.94286376
139Increased serum lactate (HP:0002151)1.93860364
140Missing ribs (HP:0000921)1.93734579
141Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.92702348
142Abnormality of the musculature of the hand (HP:0001421)1.92335863
143Cafe-au-lait spot (HP:0000957)1.92160065
144Abnormality of the distal phalanx of the thumb (HP:0009617)1.92138760
145Hepatic necrosis (HP:0002605)1.91990337
146Progressive macrocephaly (HP:0004481)1.91581325
147Abnormality of the umbilical cord (HP:0010881)1.91366222
148Tetraplegia (HP:0002445)1.91232331
149Muscle fibrillation (HP:0010546)1.90192963
150Duplication of thumb phalanx (HP:0009942)1.90071975
151Pancytopenia (HP:0001876)1.88756245
152Arteriovenous malformation (HP:0100026)1.87687541
153High pitched voice (HP:0001620)1.86703647
154Increased connective tissue (HP:0009025)1.86425151
155Small epiphyses (HP:0010585)1.85875552
156Bone marrow hypocellularity (HP:0005528)1.85458929
157Cerebral edema (HP:0002181)1.85419102
158Angiofibromas (HP:0010615)1.85005004
159Adenoma sebaceum (HP:0009720)1.85005004
160Vertebral fusion (HP:0002948)1.83567324
161Choanal atresia (HP:0000453)1.78415218
162Neoplasm of the colon (HP:0100273)1.78254250
163Overlapping toe (HP:0001845)1.76344204
164Irregular epiphyses (HP:0010582)1.75935951
165Colon cancer (HP:0003003)1.74720613
166Preaxial hand polydactyly (HP:0001177)1.73989835
167Proximal placement of thumb (HP:0009623)1.72474218
168Increased hepatocellular lipid droplets (HP:0006565)1.71182475
169Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.70776684
170Abnormal protein N-linked glycosylation (HP:0012347)1.70776684
171Abnormal protein glycosylation (HP:0012346)1.70776684
172Abnormal glycosylation (HP:0012345)1.70776684
173Abnormality of cochlea (HP:0000375)1.70050122
174Flat capital femoral epiphysis (HP:0003370)1.69945277
175Holoprosencephaly (HP:0001360)1.69162064
176Rough bone trabeculation (HP:0100670)1.66932287

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK128.12630372
2GRK54.32926920
3ERN13.90690502
4GRK63.82859787
5VRK23.47646216
6TTK3.41950545
7PBK2.91184708
8CSF1R2.70760513
9STK102.56730330
10GRK12.52655070
11BUB12.48898740
12ADRBK22.47963330
13TYRO32.25254225
14TGFBR22.17516767
15ZAK2.10246621
16CDC71.97303511
17MAPK71.96635357
18WEE11.95065530
19CDK71.93980960
20MATK1.91428002
21GRK71.87043095
22NEK21.81344723
23MOS1.78672618
24PLK11.77727173
25CHEK21.66801738
26STK161.60409087
27WNK11.58068461
28PAK41.55053205
29EPHA21.52883027
30MAP3K101.41786218
31TAF11.25494330
32PRKG21.22015243
33SMG11.15987215
34CAMK41.14611705
35MKNK21.14125973
36NUAK11.11499970
37MKNK11.11479614
38CHEK11.10825746
39TSSK61.09557004
40BRAF1.08046473
41AURKB0.99489648
42AURKA0.95209556
43NEK10.94735869
44AKT30.91951187
45SRPK10.91803313
46HIPK20.91269812
47NME10.90973957
48TRIM280.89691717
49NTRK10.88136853
50RPS6KB20.87381473
51MARK20.85814761
52TESK20.85259972
53EIF2AK20.83217890
54CDK40.82017688
55ADRBK10.79633349
56AKT20.79394023
57ALK0.75835294
58BRSK20.73436599
59MST40.72969469
60FGFR30.72329623
61EIF2AK30.71465558
62CDK20.68818308
63MST1R0.67890425
64LATS20.67026538
65EIF2AK10.66642319
66DYRK30.66522619
67MAP2K60.66039591
68TLK10.66030371
69PDK20.63673895
70MAP2K40.60018512
71BRSK10.59954714
72ATM0.59118922
73MAP3K80.58130327
74STK40.57904640
75PRKCI0.57586940
76PAK10.57381226
77MTOR0.57200923
78UHMK10.56848970
79CSK0.56205436
80ATR0.54644097
81RPS6KA40.53647863
82BCKDK0.52245175
83MARK30.49236612
84CLK10.45892056
85ACVR1B0.45326350
86CDK10.44697207
87PNCK0.42597318
88CSNK2A20.40035258
89ERBB40.39819779
90CDK140.39249904
91CSNK1G30.38989947
92DAPK10.38483068
93IRAK30.37009980
94MAPK120.36259922
95MELK0.34987896
96KDR0.34537861
97NME20.34440171
98PDK30.33921033
99PDK40.33921033
100CSNK1E0.33133100
101CSNK1G10.32225922
102CDK90.32181677
103SCYL20.32126498
104VRK10.31559991
105LIMK10.30998783
106RPS6KA50.30889780
107ERBB20.30691719
108CSNK1A1L0.28510864
109MAP3K70.28025423
110CDK80.27975757
111PLK40.27509150
112MAPKAPK30.25635119
113DYRK20.25289376
114TAOK20.25100346
115MET0.24928712
116CDK150.24423007
117CDK11A0.23937186
118MAPK110.23502964
119ICK0.22169674
120MAPK140.21649589
121PRKCD0.21457496
122CDK30.21339436
123IGF1R0.21065398
124WNK30.20726061
125MAPK10.20527507
126GSK3B0.20451212
127PASK0.20432153
128CDK180.19957462
129MAPK100.19812485
130MAPKAPK50.19607890
131CCNB10.19217831
132PRKDC0.19096533
133PIM10.18369169
134STK30.18185894
135BCR0.17580998
136PLK30.17445853
137IKBKB0.17276348
138PTK20.17252342
139MINK10.16438446
140MAP4K20.16433104
141ILK0.16308653
142CSNK2A10.16001800
143BMX0.15829468
144PKN10.15568862
145MAPK130.15280909
146BRD40.14898708
147MAPKAPK20.12925606
148ITK0.12125246
149PDGFRA0.11664319

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007505.16319964
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.47223879
3Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006034.06797277
4DNA replication_Homo sapiens_hsa030303.50693901
5Fructose and mannose metabolism_Homo sapiens_hsa000512.94485343
6Mismatch repair_Homo sapiens_hsa034302.93704485
7RNA transport_Homo sapiens_hsa030132.81565122
8Ribosome_Homo sapiens_hsa030102.57539704
9Cell cycle_Homo sapiens_hsa041102.49167391
10Homologous recombination_Homo sapiens_hsa034402.45507249
11Fanconi anemia pathway_Homo sapiens_hsa034602.42732956
12Spliceosome_Homo sapiens_hsa030402.24803586
13Base excision repair_Homo sapiens_hsa034102.07210291
14One carbon pool by folate_Homo sapiens_hsa006702.01615953
15Galactose metabolism_Homo sapiens_hsa000521.96949090
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.93761785
17Arachidonic acid metabolism_Homo sapiens_hsa005901.93583053
18mRNA surveillance pathway_Homo sapiens_hsa030151.92425764
19Parkinsons disease_Homo sapiens_hsa050121.70886020
20Oxidative phosphorylation_Homo sapiens_hsa001901.69597617
21RNA polymerase_Homo sapiens_hsa030201.69303143
22RNA degradation_Homo sapiens_hsa030181.63060947
23Nucleotide excision repair_Homo sapiens_hsa034201.57977588
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.51610351
25Linoleic acid metabolism_Homo sapiens_hsa005911.48048374
26Huntingtons disease_Homo sapiens_hsa050161.46032379
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.45980366
28p53 signaling pathway_Homo sapiens_hsa041151.45540481
29Thyroid cancer_Homo sapiens_hsa052161.38354321
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.34879803
31Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.33880569
32Pyrimidine metabolism_Homo sapiens_hsa002401.33173822
33Basal transcription factors_Homo sapiens_hsa030221.31015059
342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.29725825
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.23061554
36Protein export_Homo sapiens_hsa030601.22032110
37Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.20776385
38Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.15711732
39Pyruvate metabolism_Homo sapiens_hsa006201.15575817
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.15369227
41mTOR signaling pathway_Homo sapiens_hsa041501.14892597
42Pentose and glucuronate interconversions_Homo sapiens_hsa000401.13019227
43Non-homologous end-joining_Homo sapiens_hsa034501.12643098
44Proteasome_Homo sapiens_hsa030501.06439550
45Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.06138029
46Pentose phosphate pathway_Homo sapiens_hsa000301.04933013
47Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.00199622
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.96950060
49Alzheimers disease_Homo sapiens_hsa050100.95861084
50Transcriptional misregulation in cancer_Homo sapiens_hsa052020.91159951
51Fatty acid elongation_Homo sapiens_hsa000620.90284301
52Steroid biosynthesis_Homo sapiens_hsa001000.86044743
53Basal cell carcinoma_Homo sapiens_hsa052170.85256749
54MicroRNAs in cancer_Homo sapiens_hsa052060.85046264
55Herpes simplex infection_Homo sapiens_hsa051680.81973840
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.77378525
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76987582
58N-Glycan biosynthesis_Homo sapiens_hsa005100.75067396
59Sulfur relay system_Homo sapiens_hsa041220.74819183
60Folate biosynthesis_Homo sapiens_hsa007900.72982536
61Oocyte meiosis_Homo sapiens_hsa041140.69861092
62RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69648738
63Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69152210
64Hedgehog signaling pathway_Homo sapiens_hsa043400.68901319
65Propanoate metabolism_Homo sapiens_hsa006400.67504205
66Other glycan degradation_Homo sapiens_hsa005110.64261546
67Central carbon metabolism in cancer_Homo sapiens_hsa052300.63888298
68Alcoholism_Homo sapiens_hsa050340.63690988
69Biosynthesis of amino acids_Homo sapiens_hsa012300.62666007
70Pathways in cancer_Homo sapiens_hsa052000.61671393
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.60780855
72Hippo signaling pathway_Homo sapiens_hsa043900.60775251
73Viral carcinogenesis_Homo sapiens_hsa052030.60091862
74Bladder cancer_Homo sapiens_hsa052190.59817477
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.59166207
76HTLV-I infection_Homo sapiens_hsa051660.56869995
77Selenocompound metabolism_Homo sapiens_hsa004500.56838866
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.56409075
79Lysine degradation_Homo sapiens_hsa003100.56100945
80Carbon metabolism_Homo sapiens_hsa012000.55641754
81Acute myeloid leukemia_Homo sapiens_hsa052210.52367394
82Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51694419
83Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.48676382
84Systemic lupus erythematosus_Homo sapiens_hsa053220.48134619
85Inositol phosphate metabolism_Homo sapiens_hsa005620.45322237
86Apoptosis_Homo sapiens_hsa042100.45221627
87Non-small cell lung cancer_Homo sapiens_hsa052230.44699919
88Chemical carcinogenesis_Homo sapiens_hsa052040.44089213
89Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.43793176
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43306454
91Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.43096812
92Purine metabolism_Homo sapiens_hsa002300.42913470
93Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42784690
94Small cell lung cancer_Homo sapiens_hsa052220.42773423
95Phospholipase D signaling pathway_Homo sapiens_hsa040720.42565359
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.41190305
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41014185
98Notch signaling pathway_Homo sapiens_hsa043300.40389667
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39410935
100Ether lipid metabolism_Homo sapiens_hsa005650.37848520
101Arginine and proline metabolism_Homo sapiens_hsa003300.36040335
102Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35582468
103Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34495420
104Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.34081328
105Sulfur metabolism_Homo sapiens_hsa009200.33993868
106Cyanoamino acid metabolism_Homo sapiens_hsa004600.32201402
107Epstein-Barr virus infection_Homo sapiens_hsa051690.32159721
108Ovarian steroidogenesis_Homo sapiens_hsa049130.30688922
109Colorectal cancer_Homo sapiens_hsa052100.30451583
110Wnt signaling pathway_Homo sapiens_hsa043100.30044766
111AMPK signaling pathway_Homo sapiens_hsa041520.27054676
112Rap1 signaling pathway_Homo sapiens_hsa040150.26953258
113Fatty acid metabolism_Homo sapiens_hsa012120.26576056
114Primary immunodeficiency_Homo sapiens_hsa053400.24787755
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.24629900
116Proteoglycans in cancer_Homo sapiens_hsa052050.24519917
117Choline metabolism in cancer_Homo sapiens_hsa052310.24471820
118Cardiac muscle contraction_Homo sapiens_hsa042600.24193024
119Glutathione metabolism_Homo sapiens_hsa004800.23578993
120Tight junction_Homo sapiens_hsa045300.23107534
121TGF-beta signaling pathway_Homo sapiens_hsa043500.22987491
122Pancreatic cancer_Homo sapiens_hsa052120.21986443
123Drug metabolism - other enzymes_Homo sapiens_hsa009830.21746963
124Leukocyte transendothelial migration_Homo sapiens_hsa046700.21620831
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.20919291
126Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.20580471
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.20362829
128Adherens junction_Homo sapiens_hsa045200.20013759
129Regulation of autophagy_Homo sapiens_hsa041400.18654069
130Metabolic pathways_Homo sapiens_hsa011000.18548643
131Antigen processing and presentation_Homo sapiens_hsa046120.17259962
132NF-kappa B signaling pathway_Homo sapiens_hsa040640.15755390
133Vitamin digestion and absorption_Homo sapiens_hsa049770.15525395
134VEGF signaling pathway_Homo sapiens_hsa043700.15243894
135Butanoate metabolism_Homo sapiens_hsa006500.14273660
136Fat digestion and absorption_Homo sapiens_hsa049750.10293706
137Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.10267279
138Tyrosine metabolism_Homo sapiens_hsa003500.08976961
139Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.08715573
140Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.08543013
141Melanoma_Homo sapiens_hsa052180.08438895
142Peroxisome_Homo sapiens_hsa041460.07907378

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