CDCA7L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.74060671
2ribosomal small subunit assembly (GO:0000028)5.56920590
3DNA strand elongation involved in DNA replication (GO:0006271)5.37510743
4telomere maintenance via semi-conservative replication (GO:0032201)5.19715295
5DNA strand elongation (GO:0022616)5.16916942
6DNA replication initiation (GO:0006270)4.93956610
7DNA deamination (GO:0045006)4.65925349
8telomere maintenance via recombination (GO:0000722)4.59181763
9viral transcription (GO:0019083)4.43453957
10translational termination (GO:0006415)4.34674908
11mitotic recombination (GO:0006312)4.29891060
12maturation of SSU-rRNA (GO:0030490)4.13042595
13mitotic sister chromatid segregation (GO:0000070)4.12190389
14telomere maintenance via telomere lengthening (GO:0010833)4.05073684
15sister chromatid segregation (GO:0000819)4.03280825
16IMP biosynthetic process (GO:0006188)4.01435415
17establishment of viral latency (GO:0019043)3.98186981
18translational elongation (GO:0006414)3.93553102
19DNA ligation (GO:0006266)3.93438440
20nucleotide-excision repair, DNA gap filling (GO:0006297)3.85897031
21double-strand break repair via nonhomologous end joining (GO:0006303)3.80794653
22non-recombinational repair (GO:0000726)3.80794653
23metaphase plate congression (GO:0051310)3.80264909
24protein localization to kinetochore (GO:0034501)3.76132452
25heterochromatin organization (GO:0070828)3.74224705
26IMP metabolic process (GO:0046040)3.73308255
27DNA replication checkpoint (GO:0000076)3.73268525
28deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.72855814
29ribosomal small subunit biogenesis (GO:0042274)3.68333368
30SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.67721279
31negative regulation of chromosome segregation (GO:0051985)3.65327655
32nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65168595
33nucleobase biosynthetic process (GO:0046112)3.63492005
34negative regulation of mitotic sister chromatid separation (GO:2000816)3.62713649
35negative regulation of sister chromatid segregation (GO:0033046)3.62713649
36negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.62713649
37negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.62713649
38negative regulation of mitotic sister chromatid segregation (GO:0033048)3.62713649
39pore complex assembly (GO:0046931)3.62544981
40spindle checkpoint (GO:0031577)3.57700391
41cotranslational protein targeting to membrane (GO:0006613)3.57132234
42protein targeting to ER (GO:0045047)3.55814109
43ribosome assembly (GO:0042255)3.54751738
44regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.53777221
45mitotic spindle checkpoint (GO:0071174)3.53464626
46CENP-A containing nucleosome assembly (GO:0034080)3.51883468
47regulation of centriole replication (GO:0046599)3.50626006
48translational initiation (GO:0006413)3.50323043
49regulation of chromosome segregation (GO:0051983)3.49635835
50regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.44546513
51regulation of mitotic metaphase/anaphase transition (GO:0030071)3.44546513
52chromatin remodeling at centromere (GO:0031055)3.44205200
53positive regulation of chromosome segregation (GO:0051984)3.43299217
54translesion synthesis (GO:0019985)3.42860229
55mitotic spindle assembly checkpoint (GO:0007094)3.42634990
56ATP-dependent chromatin remodeling (GO:0043044)3.41723678
57establishment of protein localization to endoplasmic reticulum (GO:0072599)3.38393753
58spindle assembly checkpoint (GO:0071173)3.37996243
59regulation of sister chromatid segregation (GO:0033045)3.37631058
60regulation of mitotic sister chromatid separation (GO:0010965)3.37631058
61regulation of mitotic sister chromatid segregation (GO:0033047)3.37631058
62viral life cycle (GO:0019058)3.35872710
63regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.34654178
64protein localization to endoplasmic reticulum (GO:0070972)3.34046472
65ribosomal large subunit biogenesis (GO:0042273)3.33184425
66DNA replication-independent nucleosome organization (GO:0034724)3.32970652
67DNA replication-independent nucleosome assembly (GO:0006336)3.32970652
68cellular protein complex disassembly (GO:0043624)3.30849092
69formation of translation preinitiation complex (GO:0001731)3.30059037
70DNA duplex unwinding (GO:0032508)3.29637182
71DNA geometric change (GO:0032392)3.27570449
72regulation of helicase activity (GO:0051095)3.26352260
73DNA double-strand break processing (GO:0000729)3.25753968
74folic acid-containing compound biosynthetic process (GO:0009396)3.25622676
75establishment of chromosome localization (GO:0051303)3.24744459
76telomere maintenance (GO:0000723)3.24485838
77regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.23492758
78synapsis (GO:0007129)3.23171593
79telomere organization (GO:0032200)3.21918342
80regulation of DNA endoreduplication (GO:0032875)3.21872147
81replication fork processing (GO:0031297)3.21394791
82protein complex localization (GO:0031503)3.20031399
83L-serine metabolic process (GO:0006563)3.19754519
84protein localization to chromosome, centromeric region (GO:0071459)3.19515745
85negative regulation of DNA-dependent DNA replication (GO:2000104)3.18607141
86regulation of sister chromatid cohesion (GO:0007063)3.16173193
87negative regulation of mRNA processing (GO:0050686)3.13446736
88DNA catabolic process, exonucleolytic (GO:0000738)3.11470524
89DNA strand renaturation (GO:0000733)3.10891406
90protein complex disassembly (GO:0043241)3.09466155
91purine nucleobase biosynthetic process (GO:0009113)3.09341611
92ribonucleoprotein complex biogenesis (GO:0022613)3.09272659
93mitotic nuclear envelope disassembly (GO:0007077)3.06588801
94nuclear-transcribed mRNA catabolic process (GO:0000956)3.06567262
95kinetochore assembly (GO:0051382)3.05661669
96antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.03588461
97antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.03588461
98regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.03583442
99regulation of mitotic spindle checkpoint (GO:1903504)3.03583442
100chromosome segregation (GO:0007059)3.02217103
101negative regulation of RNA splicing (GO:0033119)3.01151063
102DNA replication-dependent nucleosome assembly (GO:0006335)2.98546369
103DNA replication-dependent nucleosome organization (GO:0034723)2.98546369
104establishment of integrated proviral latency (GO:0075713)2.98343511
105pseudouridine synthesis (GO:0001522)2.97930814
106mitotic sister chromatid cohesion (GO:0007064)2.96304311
107negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.95380194
108postreplication repair (GO:0006301)2.95117186
109mRNA catabolic process (GO:0006402)2.92280373
110definitive hemopoiesis (GO:0060216)2.91843517
111rRNA processing (GO:0006364)2.90926635
112macromolecular complex disassembly (GO:0032984)2.89335302
113RNA catabolic process (GO:0006401)2.88716708
114attachment of spindle microtubules to kinetochore (GO:0008608)2.86735375
115mitotic chromosome condensation (GO:0007076)2.84987814
116mismatch repair (GO:0006298)2.82401182
117intra-S DNA damage checkpoint (GO:0031573)2.82288563
118rRNA metabolic process (GO:0016072)2.81085498
119nuclear envelope disassembly (GO:0051081)2.80951589
120membrane disassembly (GO:0030397)2.80951589
121nuclear pore organization (GO:0006999)2.80448132
122ribosome biogenesis (GO:0042254)2.79770773
123kinetochore organization (GO:0051383)2.78676013
124histone exchange (GO:0043486)2.77196547
125DNA topological change (GO:0006265)2.77120097
126transcription-coupled nucleotide-excision repair (GO:0006283)2.75569489
127DNA conformation change (GO:0071103)2.75360820
128base-excision repair (GO:0006284)2.74985803
129regulation of nuclear cell cycle DNA replication (GO:0033262)2.74775871
130chromatin assembly or disassembly (GO:0006333)2.73553756
131somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.71404626
132somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.71404626
133isotype switching (GO:0045190)2.71404626
134DNA synthesis involved in DNA repair (GO:0000731)2.69064476
135histone H2A acetylation (GO:0043968)2.68640140
136nuclear pore complex assembly (GO:0051292)2.68531353
137maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.67698922
138somatic hypermutation of immunoglobulin genes (GO:0016446)2.66332535
139somatic diversification of immune receptors via somatic mutation (GO:0002566)2.66332535
140meiotic chromosome segregation (GO:0045132)2.66051988
1413-UTR-mediated mRNA stabilization (GO:0070935)2.64098845
142regulation of histone H3-K9 methylation (GO:0051570)2.63819267
143mRNA splicing, via spliceosome (GO:0000398)2.63622069
144RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.63622069
145mitotic metaphase plate congression (GO:0007080)2.62331619
146RNA splicing, via transesterification reactions (GO:0000375)2.61449591
147rRNA modification (GO:0000154)2.59829309

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.60192907
2* MYC_18555785_ChIP-Seq_MESCs_Mouse3.92968647
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.65543881
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.51346677
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.17406212
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79485031
7MYC_18358816_ChIP-ChIP_MESCs_Mouse2.51829926
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.43241007
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.43155105
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.42745946
11SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.40409447
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.37671232
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.36517320
14MYC_22102868_ChIP-Seq_BL_Human2.35542480
15EGR1_19374776_ChIP-ChIP_THP-1_Human2.27323512
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.25638233
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.20832027
18TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.20746381
19JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.17873232
20ETS1_20019798_ChIP-Seq_JURKAT_Human2.15555811
21* E2F1_21310950_ChIP-Seq_MCF-7_Human2.13834810
22SCL_19346495_ChIP-Seq_HPC-7_Human2.13791192
23VDR_23849224_ChIP-Seq_CD4+_Human2.09356808
24XRN2_22483619_ChIP-Seq_HELA_Human2.09278322
25SALL1_21062744_ChIP-ChIP_HESCs_Human2.05933583
26NELFA_20434984_ChIP-Seq_ESCs_Mouse2.02986853
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.00377766
28FOXP3_21729870_ChIP-Seq_TREG_Human1.96236373
29CREB1_15753290_ChIP-ChIP_HEK293T_Human1.89686915
30CIITA_25753668_ChIP-Seq_RAJI_Human1.89510630
31* AR_21909140_ChIP-Seq_LNCAP_Human1.80378936
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.79705580
33SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.79548225
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.78486722
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77959682
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.74359344
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.74104632
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71869294
39* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.71381792
40* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.71055768
41MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.70687092
42VDR_21846776_ChIP-Seq_THP-1_Human1.69221111
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67571650
44IRF8_22096565_ChIP-ChIP_GC-B_Human1.67179725
45GABP_19822575_ChIP-Seq_HepG2_Human1.66379348
46CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.65894569
47* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.65417400
48IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.63587843
49TTF2_22483619_ChIP-Seq_HELA_Human1.62659353
50* DCP1A_22483619_ChIP-Seq_HELA_Human1.57919406
51MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57122000
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56427239
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.56341518
54MYCN_18555785_ChIP-Seq_MESCs_Mouse1.55532481
55MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.55174514
56SPI1_23547873_ChIP-Seq_NB4_Human1.54144183
57* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.51274175
58RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.48165318
59ELK1_19687146_ChIP-ChIP_HELA_Human1.46660126
60HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.42734970
61GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.40590678
62THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37058312
63* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.36972977
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.35422133
65POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.35406041
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.28132382
67POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26924351
68SOX2_18555785_ChIP-Seq_MESCs_Mouse1.26842076
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26388532
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.23620409
71* MYB_26560356_Chip-Seq_TH2_Human1.23457188
72KDM5A_27292631_Chip-Seq_BREAST_Human1.22990194
73SOX2_16153702_ChIP-ChIP_HESCs_Human1.22641963
74KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.21805344
75TP63_19390658_ChIP-ChIP_HaCaT_Human1.20827843
76NANOG_16153702_ChIP-ChIP_HESCs_Human1.20530555
77E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.18970843
78UTX_26944678_Chip-Seq_JUKART_Human1.17372816
79MAF_26560356_Chip-Seq_TH1_Human1.16419734
80* MYB_26560356_Chip-Seq_TH1_Human1.15926679
81POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15815857
82RUNX1_22412390_ChIP-Seq_EML_Mouse1.15022734
83STAT4_19710469_ChIP-ChIP_TH1__Mouse1.14055178
84CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13706233
85ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.12042174
86NANOG_18555785_ChIP-Seq_MESCs_Mouse1.09896564
87TFEB_21752829_ChIP-Seq_HELA_Human1.09139219
88GATA1_22383799_ChIP-Seq_G1ME_Mouse1.08610978
89ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.08339605
90STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.04839932
91SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.03267242
92CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03213703
93HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.02401095
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00964509
95MYC_18940864_ChIP-ChIP_HL60_Human1.00916696
96KLF4_18555785_ChIP-Seq_MESCs_Mouse1.00695169
97YY1_21170310_ChIP-Seq_MESCs_Mouse0.99991000
98GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99625642
99VDR_24763502_ChIP-Seq_THP-1_Human0.98434468
100RBPJ_22232070_ChIP-Seq_NCS_Mouse0.96500342
101TCF7_22412390_ChIP-Seq_EML_Mouse0.96098007
102IRF8_21731497_ChIP-ChIP_J774_Mouse0.95602225
103SOX17_20123909_ChIP-Seq_XEN_Mouse0.93878210
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93843669
105* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.93803431
106BRD4_27068464_Chip-Seq_AML-cells_Mouse0.93543119
107KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.92786270
108KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.92786270
109KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.92786270
110PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91897290
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.91492074
112TCF3_18692474_ChIP-Seq_MEFs_Mouse0.90878436
113CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.90332292
114EWS_26573619_Chip-Seq_HEK293_Human0.90125291
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.89780628
116TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89174374
117CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.89042039
118MAF_26560356_Chip-Seq_TH2_Human0.88704279
119CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.87237817
120NANOG_21062744_ChIP-ChIP_HESCs_Human0.86764906
121HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.83894834
122FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83710995
123CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83513829
124BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81216746
125STAT3_1855785_ChIP-Seq_MESCs_Mouse0.80392686
126NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.79752545
127IRF1_19129219_ChIP-ChIP_H3396_Human0.74054065
128CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.73606367
129NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.72718953

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system4.37523466
2MP0010094_abnormal_chromosome_stability4.28514077
3MP0003693_abnormal_embryo_hatching3.79576440
4MP0008057_abnormal_DNA_replication3.32883732
5MP0003111_abnormal_nucleus_morphology3.27808679
6MP0004957_abnormal_blastocyst_morpholog3.15619980
7MP0003077_abnormal_cell_cycle3.14493826
8MP0004808_abnormal_hematopoietic_stem2.74584920
9MP0008007_abnormal_cellular_replicative2.74295786
10MP0008058_abnormal_DNA_repair2.70202353
11MP0003763_abnormal_thymus_physiology2.54222826
12MP0000490_abnormal_crypts_of2.33809087
13MP0003718_maternal_effect2.28170261
14MP0005397_hematopoietic_system_phenotyp2.22949989
15MP0001545_abnormal_hematopoietic_system2.22949989
16MP0003941_abnormal_skin_development2.14473378
17MP0001835_abnormal_antigen_presentation2.10655288
18MP0002398_abnormal_bone_marrow2.05254655
19MP0008877_abnormal_DNA_methylation2.02574428
20MP0005174_abnormal_tail_pigmentation2.01454965
21MP0005671_abnormal_response_to1.99496164
22MP0010352_gastrointestinal_tract_polyps1.94335915
23MP0006054_spinal_hemorrhage1.85414264
24MP0005075_abnormal_melanosome_morpholog1.82137745
25MP0000685_abnormal_immune_system1.80534586
26MP0008932_abnormal_embryonic_tissue1.76330257
27MP0002722_abnormal_immune_system1.74952901
28MP0000689_abnormal_spleen_morphology1.74516377
29MP0000703_abnormal_thymus_morphology1.69806324
30MP0002095_abnormal_skin_pigmentation1.69210767
31MP0009333_abnormal_splenocyte_physiolog1.68898710
32MP0002019_abnormal_tumor_incidence1.66050018
33MP0000350_abnormal_cell_proliferation1.65230761
34MP0009672_abnormal_birth_weight1.58172720
35MP0010307_abnormal_tumor_latency1.58149597
36MP0001800_abnormal_humoral_immune1.57002240
37MP0002429_abnormal_blood_cell1.56595713
38MP0002420_abnormal_adaptive_immunity1.56034744
39MP0000716_abnormal_immune_system1.55966244
40MP0009785_altered_susceptibility_to1.55898515
41MP0001819_abnormal_immune_cell1.52780945
42MP0001730_embryonic_growth_arrest1.52348540
43MP0003806_abnormal_nucleotide_metabolis1.52194685
44MP0005464_abnormal_platelet_physiology1.51218543
45MP0003890_abnormal_embryonic-extraembry1.49810686
46MP0003786_premature_aging1.48597913
47MP0004147_increased_porphyrin_level1.47843955
48MP0002166_altered_tumor_susceptibility1.47073891
49MP0002452_abnormal_antigen_presenting1.45886231
50MP0000465_gastrointestinal_hemorrhage1.44667024
51MP0010030_abnormal_orbit_morphology1.43604808
52MP0001873_stomach_inflammation1.42328560
53MP0000313_abnormal_cell_death1.42232313
54MP0003937_abnormal_limbs/digits/tail_de1.38008231
55MP0001853_heart_inflammation1.37504763
56MP0002723_abnormal_immune_serum1.37119623
57MP0005025_abnormal_response_to1.36970606
58MP0009278_abnormal_bone_marrow1.36763716
59MP0010155_abnormal_intestine_physiology1.27243024
60MP0002006_tumorigenesis1.26721330
61MP0005000_abnormal_immune_tolerance1.20057480
62MP0002877_abnormal_melanocyte_morpholog1.18058741
63MP0002080_prenatal_lethality1.16689980
64MP0003567_abnormal_fetal_cardiomyocyte1.16215772
65MP0002405_respiratory_system_inflammati1.15742332
66MP0002697_abnormal_eye_size1.15482259
67MP0003123_paternal_imprinting1.13748177
68MP0009703_decreased_birth_body1.12000044
69MP0001697_abnormal_embryo_size1.11996716
70MP0006035_abnormal_mitochondrial_morpho1.11928769
71MP0001286_abnormal_eye_development1.10333599
72MP0003136_yellow_coat_color1.09536662
73MP0008789_abnormal_olfactory_epithelium1.09487477
74MP0000537_abnormal_urethra_morphology1.09130649
75MP0002132_abnormal_respiratory_system1.08078562
76MP0003436_decreased_susceptibility_to1.07970148
77MP0000015_abnormal_ear_pigmentation1.05655702
78MP0001672_abnormal_embryogenesis/_devel1.04569655
79MP0005380_embryogenesis_phenotype1.04569655
80MP0003866_abnormal_defecation1.03630979
81MP0000428_abnormal_craniofacial_morphol1.02910789
82MP0003984_embryonic_growth_retardation1.00802863
83MP0004185_abnormal_adipocyte_glucose1.00707723
84MP0002419_abnormal_innate_immunity1.00395843
85MP0003943_abnormal_hepatobiliary_system1.00064101
86MP0006292_abnormal_olfactory_placode0.99616285
87MP0002233_abnormal_nose_morphology0.99608234
88MP0002088_abnormal_embryonic_growth/wei0.96039180
89MP0001293_anophthalmia0.95791612
90MP0000858_altered_metastatic_potential0.94832677
91MP0002086_abnormal_extraembryonic_tissu0.94192326
92MP0002009_preneoplasia0.93932214
93MP0002092_abnormal_eye_morphology0.91911941
94MP0002254_reproductive_system_inflammat0.91421053
95MP0002111_abnormal_tail_morphology0.90830120
96MP0002148_abnormal_hypersensitivity_rea0.89072288
97MP0000579_abnormal_nail_morphology0.88559541
98MP0002075_abnormal_coat/hair_pigmentati0.88475954
99MP0001790_abnormal_immune_system0.88317297
100MP0005387_immune_system_phenotype0.88317297
101MP0002210_abnormal_sex_determination0.86035277
102MP0000477_abnormal_intestine_morphology0.85627247
103MP0002938_white_spotting0.85419233
104MP0006072_abnormal_retinal_apoptosis0.84372402
105MP0002085_abnormal_embryonic_tissue0.84043082
106MP0002084_abnormal_developmental_patter0.82431174
107MP0004197_abnormal_fetal_growth/weight/0.82131343
108MP0005384_cellular_phenotype0.82039812
109MP0005501_abnormal_skin_physiology0.81273273
110MP0005621_abnormal_cell_physiology0.79197043
111MP0000049_abnormal_middle_ear0.78366686
112MP0001145_abnormal_male_reproductive0.78022777
113MP0003119_abnormal_digestive_system0.76980946
114MP0001845_abnormal_inflammatory_respons0.76809751
115MP0005499_abnormal_olfactory_system0.76544913
116MP0005394_taste/olfaction_phenotype0.76544913
117MP0001661_extended_life_span0.75755985
118MP0005076_abnormal_cell_differentiation0.75456305
119MP0002796_impaired_skin_barrier0.72984936
120MP0000383_abnormal_hair_follicle0.71797217
121MP0009697_abnormal_copulation0.71248664
122MP0009379_abnormal_foot_pigmentation0.70976286
123MP0003121_genomic_imprinting0.70925643
124MP0001929_abnormal_gametogenesis0.70242335
125MP0003861_abnormal_nervous_system0.69919830
126MP0001188_hyperpigmentation0.69643790
127MP0003724_increased_susceptibility_to0.69311894
128MP0004233_abnormal_muscle_weight0.69012299
129MP0005395_other_phenotype0.68742568
130MP0003698_abnormal_male_reproductive0.68686207
131MP0000371_diluted_coat_color0.67609925
132MP0001849_ear_inflammation0.66940259
133MP0000432_abnormal_head_morphology0.66609278
134MP0000653_abnormal_sex_gland0.65459033
135MP0001119_abnormal_female_reproductive0.65178476
136MP0003755_abnormal_palate_morphology0.64556438
137MP0000566_synostosis0.63650555
138MP0001915_intracranial_hemorrhage0.63541537
139MP0009053_abnormal_anal_canal0.62914940
140MP0000358_abnormal_cell_content/0.62303391
141MP0003656_abnormal_erythrocyte_physiolo0.61440326
142MP0005391_vision/eye_phenotype0.61033069
143MP0005023_abnormal_wound_healing0.60841124
144MP0000762_abnormal_tongue_morphology0.60575741
145MP0003935_abnormal_craniofacial_develop0.60475143
146MP0002234_abnormal_pharynx_morphology0.60460223
147MP0003705_abnormal_hypodermis_morpholog0.59723558
148MP0003186_abnormal_redox_activity0.59456558
149MP0006036_abnormal_mitochondrial_physio0.59281610

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)5.22158986
2Abnormality of cells of the erythroid lineage (HP:0012130)4.76931498
3Abnormal number of erythroid precursors (HP:0012131)4.72971833
4Reticulocytopenia (HP:0001896)4.68906496
5Thrombocytosis (HP:0001894)4.25687723
6IgM deficiency (HP:0002850)4.08774984
7Birth length less than 3rd percentile (HP:0003561)3.58049380
8Abnormality of the labia minora (HP:0012880)3.56541123
9Nephroblastoma (Wilms tumor) (HP:0002667)3.39262159
10Colon cancer (HP:0003003)3.38934174
11Chromsome breakage (HP:0040012)3.28403980
12Pallor (HP:0000980)3.25709213
13Myelodysplasia (HP:0002863)3.18627219
14Embryonal renal neoplasm (HP:0011794)3.15766856
15Oral leukoplakia (HP:0002745)3.13651658
16Chronic otitis media (HP:0000389)3.13430464
17Elevated erythrocyte sedimentation rate (HP:0003565)2.98560134
18Abnormality of chromosome stability (HP:0003220)2.91630818
19Poikiloderma (HP:0001029)2.85554639
2011 pairs of ribs (HP:0000878)2.85362003
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82938206
22Recurrent bronchitis (HP:0002837)2.79635001
23Microvesicular hepatic steatosis (HP:0001414)2.76566206
24Abnormality of the duodenum (HP:0002246)2.74259415
25Multiple enchondromatosis (HP:0005701)2.70698687
26Acute myeloid leukemia (HP:0004808)2.68374016
27Macrocytic anemia (HP:0001972)2.67069738
28Abnormality of the heme biosynthetic pathway (HP:0010472)2.66866651
29Abnormality of the preputium (HP:0100587)2.66402498
30Basal cell carcinoma (HP:0002671)2.61505004
31Abnormality of T cell physiology (HP:0011840)2.61331437
32Lymphoma (HP:0002665)2.61044472
33Microretrognathia (HP:0000308)2.58785803
34Medulloblastoma (HP:0002885)2.57841273
35Selective tooth agenesis (HP:0001592)2.57102728
36Pancytopenia (HP:0001876)2.56370529
37Petechiae (HP:0000967)2.56363520
38Abnormality of T cells (HP:0002843)2.55625923
39Myositis (HP:0100614)2.51068497
40Muscle fiber atrophy (HP:0100295)2.46762107
41Glioma (HP:0009733)2.46299995
42Amaurosis fugax (HP:0100576)2.46067481
43Agnosia (HP:0010524)2.45104874
44Acute lymphatic leukemia (HP:0006721)2.44891653
45Triphalangeal thumb (HP:0001199)2.43743207
46Prolonged bleeding time (HP:0003010)2.42564021
47Bone marrow hypocellularity (HP:0005528)2.36400244
48Spastic diplegia (HP:0001264)2.35899446
49Volvulus (HP:0002580)2.35405691
50Absent radius (HP:0003974)2.34521907
51Type 2 muscle fiber atrophy (HP:0003554)2.33806808
52IgG deficiency (HP:0004315)2.33167643
53Cortical dysplasia (HP:0002539)2.32144481
54Cafe-au-lait spot (HP:0000957)2.30708820
55Cutaneous melanoma (HP:0012056)2.28761575
56Abnormality of the fingertips (HP:0001211)2.28208416
57Entropion (HP:0000621)2.27870416
58Premature graying of hair (HP:0002216)2.26989492
59Meckel diverticulum (HP:0002245)2.26860163
60Facial cleft (HP:0002006)2.26847882
61Recurrent viral infections (HP:0004429)2.26106461
62Absent thumb (HP:0009777)2.25940961
63Astrocytoma (HP:0009592)2.24839210
64Abnormality of the astrocytes (HP:0100707)2.24839210
65Abnormality of DNA repair (HP:0003254)2.22407441
66Aplasia/Hypoplasia of the uvula (HP:0010293)2.21162224
67Abnormality of the ileum (HP:0001549)2.18095978
68Aplasia involving forearm bones (HP:0009822)2.11885578
69Absent forearm bone (HP:0003953)2.11885578
70Increased nuchal translucency (HP:0010880)2.10532224
71Aplasia/Hypoplasia of the sternum (HP:0006714)2.10104182
72T lymphocytopenia (HP:0005403)2.09717958
73Lymphopenia (HP:0001888)2.09078624
74Type I transferrin isoform profile (HP:0003642)2.08872437
75Horseshoe kidney (HP:0000085)2.08178907
76Panhypogammaglobulinemia (HP:0003139)2.07369781
77Abnormality of cells of the lymphoid lineage (HP:0012140)2.07122707
78Clubbing of toes (HP:0100760)2.06452731
79Embryonal neoplasm (HP:0002898)2.05787871
80Malignant gastrointestinal tract tumors (HP:0006749)2.02225151
81Gastrointestinal carcinoma (HP:0002672)2.02225151
82Squamous cell carcinoma (HP:0002860)2.02177122
83Duodenal stenosis (HP:0100867)2.01969221
84Small intestinal stenosis (HP:0012848)2.01969221
85Progressive external ophthalmoplegia (HP:0000590)2.01185703
86Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.01098618
87Decreased activity of mitochondrial respiratory chain (HP:0008972)2.01098618
88Biliary tract neoplasm (HP:0100574)1.98907120
89Carpal bone hypoplasia (HP:0001498)1.98869246
90Duplication of thumb phalanx (HP:0009942)1.98099388
91Abnormality of B cell number (HP:0010975)1.97836444
92B lymphocytopenia (HP:0010976)1.97836444
93Choanal atresia (HP:0000453)1.96863763
94Neoplasm of the small intestine (HP:0100833)1.96593727
95Microglossia (HP:0000171)1.95709579
96Asplenia (HP:0001746)1.94957159
97Patellar aplasia (HP:0006443)1.93773843
98Abnormality of the prostate (HP:0008775)1.93142476
99Deviation of the thumb (HP:0009603)1.92409018
100Abnormal number of incisors (HP:0011064)1.92235107
101Abnormality of cochlea (HP:0000375)1.91989697
102Cellulitis (HP:0100658)1.91673627
103Degeneration of anterior horn cells (HP:0002398)1.91123216
104Abnormality of the anterior horn cell (HP:0006802)1.91123216
105High pitched voice (HP:0001620)1.90809155
106Hypoplasia of the thymus (HP:0000778)1.90762844
107Neoplasm of the pancreas (HP:0002894)1.90579440
108Abnormality of the carotid arteries (HP:0005344)1.90412863
109Stenosis of the external auditory canal (HP:0000402)1.90285381
110Spinal cord lesions (HP:0100561)1.88670018
111Syringomyelia (HP:0003396)1.88670018
112Ependymoma (HP:0002888)1.87542063
113Abnormality of T cell number (HP:0011839)1.86654150
114Abnormal lung lobation (HP:0002101)1.84949958
115Aplasia/Hypoplasia of the thymus (HP:0010515)1.84799681
116Abnormal delayed hypersensitivity skin test (HP:0002963)1.84328841
117Neoplasm of the adrenal cortex (HP:0100641)1.84041408
118Neoplasm of striated muscle (HP:0009728)1.83549395
119Pulmonary fibrosis (HP:0002206)1.83541768
120Slender long bone (HP:0003100)1.83463508
121Cellular immunodeficiency (HP:0005374)1.83451282
122Prominent nose (HP:0000448)1.81361290
123Ectopic kidney (HP:0000086)1.81311658
124High anterior hairline (HP:0009890)1.80910194
125Atresia of the external auditory canal (HP:0000413)1.80275210
126Abnormal spermatogenesis (HP:0008669)1.78793000
127Sloping forehead (HP:0000340)1.78347268
128Impulsivity (HP:0100710)1.78229704
129Neoplasm of the colon (HP:0100273)1.78227546
130Rough bone trabeculation (HP:0100670)1.77347493
131Tracheoesophageal fistula (HP:0002575)1.75337577
132Rhabdomyosarcoma (HP:0002859)1.74704957
133Aplasia/Hypoplasia of the spleen (HP:0010451)1.74444911
134Aplasia/Hypoplasia of the patella (HP:0006498)1.74405294
135Hyperglycinemia (HP:0002154)1.74358107
136Neuroblastic tumors (HP:0004376)1.73551260
137Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.73551260
138Neuroblastoma (HP:0003006)1.73551260
139Primitive neuroectodermal tumor (HP:0030065)1.73551260
140Septo-optic dysplasia (HP:0100842)1.73386459
141Epistaxis (HP:0000421)1.73352080
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.73098593
143Recurrent abscess formation (HP:0002722)1.72379275
144Progressive muscle weakness (HP:0003323)1.72343809
145Agammaglobulinemia (HP:0004432)1.71917318
146Proximal placement of thumb (HP:0009623)1.71569895
147Deep philtrum (HP:0002002)1.71339979
148Arteriovenous malformation (HP:0100026)1.70633009
149Neoplasm of the rectum (HP:0100743)1.70186458
150Shoulder girdle muscle weakness (HP:0003547)1.70178723
151Premature ovarian failure (HP:0008209)1.70124003
152Uterine neoplasm (HP:0010784)1.68186474
153Ovarian neoplasm (HP:0100615)1.63845149
154Abnormality of methionine metabolism (HP:0010901)1.63223884
155Neoplasm of the oral cavity (HP:0100649)1.62719898
156Capillary hemangiomas (HP:0005306)1.60367626

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC73.96063880
2WEE13.88017525
3VRK23.09392218
4PBK2.93692529
5EEF2K2.71432003
6TAF12.68574994
7ACVR1B2.58432684
8MAP4K12.39180418
9KIT2.34780152
10FLT32.34735802
11NME22.34187847
12BRSK22.31463720
13ZAK2.31017144
14BUB12.15739285
15NEK22.14954953
16TGFBR12.12140010
17BRD41.97614930
18RPS6KB21.91780754
19PASK1.88456185
20MKNK11.84968474
21SRPK11.81062216
22BTK1.75036876
23ATR1.73622315
24VRK11.72445632
25RPS6KA41.71413649
26TEC1.66719801
27SMG11.66162144
28EIF2AK11.65028548
29DYRK31.54347397
30SCYL21.51007690
31CDK71.50939577
32MAP2K31.49938375
33PKN21.46892989
34NUAK11.44026846
35JAK31.43886869
36CCNB11.42116683
37STK161.38539960
38MST41.38474068
39CDK41.37723000
40CDK81.37423870
41PNCK1.31470985
42PLK11.30167858
43AURKB1.29008366
44TSSK61.28966786
45STK101.26125423
46KDR1.25997646
47TTK1.23354366
48MKNK21.21841080
49CSF1R1.21736092
50EIF2AK31.18988368
51ZAP701.16931414
52PIM21.16818598
53MAP3K101.16573098
54PLK41.10242448
55TLK11.09833598
56BRSK11.09487441
57LRRK21.08522781
58TXK1.04921929
59TESK21.04686898
60MAP3K81.00747811
61MATK0.99162745
62EIF2AK20.97448950
63STK40.97223141
64CLK10.97006434
65PAK40.96580008
66PIM10.91593265
67NEK90.88209983
68IRAK40.87017095
69CHEK20.80349929
70STK30.80198577
71ERBB40.79418216
72CHEK10.76700589
73BMPR1B0.76139703
74MAP3K110.75592514
75TNIK0.74918189
76MAPKAPK30.74864992
77SYK0.74808101
78CDK190.73424660
79TBK10.73264916
80CDK60.72068401
81MET0.69966106
82PDK20.69365758
83BCKDK0.68756292
84BLK0.68316141
85STK38L0.66132792
86TYK20.63264294
87LYN0.62978951
88GRK60.62587058
89ATM0.61684345
90NME10.60969675
91CDK90.60488782
92TRIM280.60456531
93LCK0.60243490
94STK240.59776917
95PLK30.56565126
96CDK20.55597532
97CDK120.55534546
98DYRK20.55471106
99MAPKAPK50.55290339
100IKBKE0.54214525
101CSNK2A20.53520759
102LATS10.53507541
103AURKA0.52912807
104NEK10.52795907
105DAPK10.51482767
106WNK30.50763946
107MST1R0.48897489
108ITK0.48724157
109CSNK1G10.47337256
110MELK0.46661798
111CSNK2A10.45976707
112PRKDC0.45810082
113NLK0.43761228
114MAPK110.43302707
115RPS6KA50.43018962
116TGFBR20.40761650
117MAP3K60.40725270
118IKBKB0.40565994
119TIE10.38932833
120BRAF0.38442804
121ILK0.37954057
122CDK30.37827454
123FGFR10.37822601
124MAP2K60.35068720
125MAP3K120.34695168
126HIPK20.34391301
127ALK0.34181382
128RPS6KB10.31623812
129CDK10.30602135
130YES10.30073006
131CSNK1E0.29605909
132BMX0.28632752
133CSNK1G30.23360262
134CDK11A0.20994800
135MAPK140.20890552
136STK390.18581734
137RPS6KA10.17201531

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.70745013
2Mismatch repair_Homo sapiens_hsa034304.37719106
3Ribosome_Homo sapiens_hsa030103.59334892
4Base excision repair_Homo sapiens_hsa034103.35134521
5Homologous recombination_Homo sapiens_hsa034403.05492936
6Spliceosome_Homo sapiens_hsa030402.85098876
7Nucleotide excision repair_Homo sapiens_hsa034202.76986994
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.63090934
9Cell cycle_Homo sapiens_hsa041102.57888117
10RNA polymerase_Homo sapiens_hsa030202.56693582
11Pyrimidine metabolism_Homo sapiens_hsa002402.47805609
12RNA transport_Homo sapiens_hsa030132.24670237
13One carbon pool by folate_Homo sapiens_hsa006702.23635988
14Non-homologous end-joining_Homo sapiens_hsa034502.22308228
15Fanconi anemia pathway_Homo sapiens_hsa034602.03011384
16Proteasome_Homo sapiens_hsa030502.02139557
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.93615570
18RNA degradation_Homo sapiens_hsa030181.82266463
19Primary immunodeficiency_Homo sapiens_hsa053401.59119790
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.58717270
21Basal transcription factors_Homo sapiens_hsa030221.52361254
22Herpes simplex infection_Homo sapiens_hsa051681.37545929
23p53 signaling pathway_Homo sapiens_hsa041151.35570764
24Antigen processing and presentation_Homo sapiens_hsa046121.33256938
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.26216518
26Purine metabolism_Homo sapiens_hsa002301.22431833
27mRNA surveillance pathway_Homo sapiens_hsa030151.22417347
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.19300013
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.14718467
30Carbon metabolism_Homo sapiens_hsa012001.13810139
31Fatty acid elongation_Homo sapiens_hsa000621.12957246
32Propanoate metabolism_Homo sapiens_hsa006401.07542891
33Pyruvate metabolism_Homo sapiens_hsa006201.04569425
34Measles_Homo sapiens_hsa051621.03727055
35Thyroid cancer_Homo sapiens_hsa052161.03033732
36Epstein-Barr virus infection_Homo sapiens_hsa051691.01612448
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.98568771
38Hematopoietic cell lineage_Homo sapiens_hsa046400.96361521
39Transcriptional misregulation in cancer_Homo sapiens_hsa052020.95870183
40Viral carcinogenesis_Homo sapiens_hsa052030.94834909
41Systemic lupus erythematosus_Homo sapiens_hsa053220.93590271
42Lysine degradation_Homo sapiens_hsa003100.93465638
43Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90637539
44Legionellosis_Homo sapiens_hsa051340.88665691
45Sulfur relay system_Homo sapiens_hsa041220.86204413
46Leishmaniasis_Homo sapiens_hsa051400.86101149
47Pentose phosphate pathway_Homo sapiens_hsa000300.85290994
48RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.84125962
49HTLV-I infection_Homo sapiens_hsa051660.83824707
50Folate biosynthesis_Homo sapiens_hsa007900.83312841
51NF-kappa B signaling pathway_Homo sapiens_hsa040640.82823613
52N-Glycan biosynthesis_Homo sapiens_hsa005100.82731313
53Caffeine metabolism_Homo sapiens_hsa002320.78660411
54B cell receptor signaling pathway_Homo sapiens_hsa046620.77736159
55Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.76670234
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.76495505
57Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74819377
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.74607499
59Shigellosis_Homo sapiens_hsa051310.74265967
60Hepatitis B_Homo sapiens_hsa051610.73217849
61Glutathione metabolism_Homo sapiens_hsa004800.71274145
62Acute myeloid leukemia_Homo sapiens_hsa052210.70911402
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.69583595
64Vitamin B6 metabolism_Homo sapiens_hsa007500.68916265
65Huntingtons disease_Homo sapiens_hsa050160.68909896
66Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68117838
67Small cell lung cancer_Homo sapiens_hsa052220.66917242
68Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.65993417
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64370921
70Chronic myeloid leukemia_Homo sapiens_hsa052200.63684731
71Selenocompound metabolism_Homo sapiens_hsa004500.61642488
72Apoptosis_Homo sapiens_hsa042100.60196497
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59184076
74Jak-STAT signaling pathway_Homo sapiens_hsa046300.58160730
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57695312
76Influenza A_Homo sapiens_hsa051640.56495072
77Cysteine and methionine metabolism_Homo sapiens_hsa002700.55622311
78Protein export_Homo sapiens_hsa030600.55607270
79Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.55379712
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55361688
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.54322534
82Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52469784
83Basal cell carcinoma_Homo sapiens_hsa052170.51886946
84Oocyte meiosis_Homo sapiens_hsa041140.49006950
85Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.48907840
86Adherens junction_Homo sapiens_hsa045200.48491507
87Parkinsons disease_Homo sapiens_hsa050120.46104606
88Non-small cell lung cancer_Homo sapiens_hsa052230.45603042
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45101393
90MicroRNAs in cancer_Homo sapiens_hsa052060.44669590
91Platelet activation_Homo sapiens_hsa046110.44065758
92Other glycan degradation_Homo sapiens_hsa005110.43857044
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.43814477
94Colorectal cancer_Homo sapiens_hsa052100.43565135
95Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43356954
96Pancreatic cancer_Homo sapiens_hsa052120.43186685
97TGF-beta signaling pathway_Homo sapiens_hsa043500.43060077
98Viral myocarditis_Homo sapiens_hsa054160.41951849
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.40983495
100Biosynthesis of amino acids_Homo sapiens_hsa012300.40709316
101Hippo signaling pathway_Homo sapiens_hsa043900.40344959
102Wnt signaling pathway_Homo sapiens_hsa043100.39824534
103T cell receptor signaling pathway_Homo sapiens_hsa046600.39707759
104Prostate cancer_Homo sapiens_hsa052150.39550699
105Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.38291155
106Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38117550
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37112110
108Toxoplasmosis_Homo sapiens_hsa051450.36729629
109Toll-like receptor signaling pathway_Homo sapiens_hsa046200.34832259
110Allograft rejection_Homo sapiens_hsa053300.34574725
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.34435087
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.33830349
113Steroid biosynthesis_Homo sapiens_hsa001000.32622729
114Osteoclast differentiation_Homo sapiens_hsa043800.32374527
115Metabolic pathways_Homo sapiens_hsa011000.32271155
116Notch signaling pathway_Homo sapiens_hsa043300.31435216
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30377992
118Leukocyte transendothelial migration_Homo sapiens_hsa046700.29582876
119Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29104780
120Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.28488506
121Alcoholism_Homo sapiens_hsa050340.28420167
122Melanoma_Homo sapiens_hsa052180.27721048
123Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27233600
124Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26627634
125Pertussis_Homo sapiens_hsa051330.26541618
126Hedgehog signaling pathway_Homo sapiens_hsa043400.24388258
127Pathways in cancer_Homo sapiens_hsa052000.23554056
128Asthma_Homo sapiens_hsa053100.23207835
129HIF-1 signaling pathway_Homo sapiens_hsa040660.22731625
130Galactose metabolism_Homo sapiens_hsa000520.21853191
131Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.21705292
132Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.21306262
133Malaria_Homo sapiens_hsa051440.20886392
134Bladder cancer_Homo sapiens_hsa052190.20602809
135Fatty acid metabolism_Homo sapiens_hsa012120.20466359
136Oxidative phosphorylation_Homo sapiens_hsa001900.13801266
137Tight junction_Homo sapiens_hsa045300.08091265
138Pentose and glucuronate interconversions_Homo sapiens_hsa000400.04052754
139beta-Alanine metabolism_Homo sapiens_hsa004100.03934048
140Alzheimers disease_Homo sapiens_hsa050100.00798112

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