CDH24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.02450456
2semaphorin-plexin signaling pathway (GO:0071526)3.95970290
3negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.87852227
4convergent extension (GO:0060026)3.83527355
5regulation of chemokine-mediated signaling pathway (GO:0070099)3.73978868
6protein retention in ER lumen (GO:0006621)3.68741827
7Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.51052942
8maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.47904006
9establishment of nucleus localization (GO:0040023)3.46708040
10negative regulation of oligodendrocyte differentiation (GO:0048715)3.42652376
11nucleosome disassembly (GO:0006337)3.38334022
12protein-DNA complex disassembly (GO:0032986)3.38334022
13establishment of apical/basal cell polarity (GO:0035089)3.36784112
14glucocorticoid receptor signaling pathway (GO:0042921)3.31208826
15regulation of establishment of planar polarity (GO:0090175)3.30970819
16peptidyl-arginine omega-N-methylation (GO:0035247)3.30665643
17negative regulation of RNA splicing (GO:0033119)3.30017905
18negative regulation of histone methylation (GO:0031061)3.27871634
19DNA unwinding involved in DNA replication (GO:0006268)3.27610938
20cell-substrate adherens junction assembly (GO:0007045)3.23483615
21focal adhesion assembly (GO:0048041)3.23483615
22mitotic sister chromatid cohesion (GO:0007064)3.20808656
23regulation of sister chromatid cohesion (GO:0007063)3.19573607
24layer formation in cerebral cortex (GO:0021819)3.19312652
25negative regulation of mRNA processing (GO:0050686)3.18267658
26peptidyl-arginine N-methylation (GO:0035246)3.18226611
27peptidyl-arginine methylation (GO:0018216)3.18226611
28nuclear pore complex assembly (GO:0051292)3.15592712
29regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.13929691
30planar cell polarity pathway involved in neural tube closure (GO:0090179)3.11908149
31cochlea morphogenesis (GO:0090103)3.10697634
32regulation of RNA export from nucleus (GO:0046831)3.07571120
33cell migration involved in sprouting angiogenesis (GO:0002042)3.06437296
34dosage compensation (GO:0007549)3.05592428
35apoptotic process involved in morphogenesis (GO:0060561)2.99676276
36polarized epithelial cell differentiation (GO:0030859)2.99017405
37regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.97694721
38positive regulation of RNA splicing (GO:0033120)2.95790892
39RNA stabilization (GO:0043489)2.93217425
40mRNA stabilization (GO:0048255)2.93217425
41stress granule assembly (GO:0034063)2.93162683
42bone trabecula formation (GO:0060346)2.92790127
43intracellular estrogen receptor signaling pathway (GO:0030520)2.91356444
44head development (GO:0060322)2.90965884
45dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.90668072
46negative regulation of translation, ncRNA-mediated (GO:0040033)2.89114148
47regulation of translation, ncRNA-mediated (GO:0045974)2.89114148
48negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89114148
49notochord development (GO:0030903)2.88777284
50negative regulation of chondrocyte differentiation (GO:0032331)2.87761496
51response to pheromone (GO:0019236)2.87534675
52nuclear pore organization (GO:0006999)2.86286238
53cytoplasmic mRNA processing body assembly (GO:0033962)2.86157844
54activation of Rac GTPase activity (GO:0032863)2.85880667
55negative regulation of mRNA metabolic process (GO:1903312)2.85749106
56establishment of monopolar cell polarity (GO:0061162)2.85695393
57establishment or maintenance of monopolar cell polarity (GO:0061339)2.85695393
58peptidyl-lysine dimethylation (GO:0018027)2.84777419
59sister chromatid segregation (GO:0000819)2.84529880
60proximal/distal pattern formation (GO:0009954)2.84198729
61positive regulation of gene expression, epigenetic (GO:0045815)2.83968484
62positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.83497121
63regulation of translational fidelity (GO:0006450)2.83312393
64embryonic foregut morphogenesis (GO:0048617)2.83012211
65heterochromatin organization (GO:0070828)2.81562042
66alternative mRNA splicing, via spliceosome (GO:0000380)2.81479979
67neuron recognition (GO:0008038)2.80153053
68corticosteroid receptor signaling pathway (GO:0031958)2.76791246
69axonal fasciculation (GO:0007413)2.76511764
70non-canonical Wnt signaling pathway (GO:0035567)2.75552251
71protein localization to kinetochore (GO:0034501)2.75139247
72axon extension involved in axon guidance (GO:0048846)2.74174222
73histone H2A monoubiquitination (GO:0035518)2.71466762
74cell-substrate junction assembly (GO:0007044)2.69209106
75cell migration in hindbrain (GO:0021535)2.68284375
76negative regulation of catenin import into nucleus (GO:0035414)2.67674826
77hippo signaling (GO:0035329)2.67548737
78camera-type eye morphogenesis (GO:0048593)2.67312749
79regulation of NFAT protein import into nucleus (GO:0051532)2.66883314
80regulation of mitotic spindle organization (GO:0060236)2.65886134
81mitotic chromosome condensation (GO:0007076)2.65690583
82regulation of axon extension involved in axon guidance (GO:0048841)2.65242754
83eye morphogenesis (GO:0048592)2.64323012
84establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.64274210
85mitochondrion transport along microtubule (GO:0047497)2.64274210
86dorsal/ventral axis specification (GO:0009950)2.62479779
87gene silencing by RNA (GO:0031047)2.62032099
88establishment or maintenance of apical/basal cell polarity (GO:0035088)2.61707490
89establishment or maintenance of bipolar cell polarity (GO:0061245)2.61707490
90mRNA splice site selection (GO:0006376)2.60624509
91V(D)J recombination (GO:0033151)2.58789596
92branching involved in salivary gland morphogenesis (GO:0060445)2.56048081
93gene silencing (GO:0016458)2.55848982
94atrioventricular valve morphogenesis (GO:0003181)2.54126274
95neural tube development (GO:0021915)2.53162842
96paraxial mesoderm development (GO:0048339)2.52895627
97gastrulation with mouth forming second (GO:0001702)2.52404801
98histone H4-K16 acetylation (GO:0043984)2.51782481
99COPI coating of Golgi vesicle (GO:0048205)2.51383069
100Golgi transport vesicle coating (GO:0048200)2.51383069
101cranial nerve morphogenesis (GO:0021602)2.50498162
102histone H3-K36 demethylation (GO:0070544)2.49579047
103embryonic eye morphogenesis (GO:0048048)2.49243159
104G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.48667295
105regulation of glucose import in response to insulin stimulus (GO:2001273)2.48370178
106histone H3-K4 trimethylation (GO:0080182)2.48113775
107facial nerve structural organization (GO:0021612)2.47881374
108regulation of nucleobase-containing compound transport (GO:0032239)2.47874473
109establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.46253614
110synaptic vesicle docking involved in exocytosis (GO:0016081)2.45973597
111histone H4 acetylation (GO:0043967)2.45681788
112establishment of tissue polarity (GO:0007164)2.44284977
113establishment of planar polarity (GO:0001736)2.44284977
114cell-cell junction maintenance (GO:0045217)2.44157378
115negative regulation of cell size (GO:0045792)2.43601341
116adherens junction assembly (GO:0034333)2.42798974
117apoptotic process involved in development (GO:1902742)2.42257051
118histone arginine methylation (GO:0034969)2.41665756
119regulation of mammary gland epithelial cell proliferation (GO:0033599)2.40872349
120lateral sprouting from an epithelium (GO:0060601)2.40555623
121histone H3-K4 methylation (GO:0051568)2.40526602
122negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.40433151
123negative regulation of cell killing (GO:0031342)2.40433151
124positive T cell selection (GO:0043368)2.40386092
125spliceosomal tri-snRNP complex assembly (GO:0000244)2.39769784
126NLS-bearing protein import into nucleus (GO:0006607)2.39443133
127regulation of mRNA stability (GO:0043488)2.39202062
128negative T cell selection (GO:0043383)2.38648999
129mitotic sister chromatid segregation (GO:0000070)2.38638415
130body morphogenesis (GO:0010171)2.37218075
1313-UTR-mediated mRNA stabilization (GO:0070935)2.37175110
132histone H4-K8 acetylation (GO:0043982)2.35555012
133histone H4-K5 acetylation (GO:0043981)2.35555012
134cytoskeletal anchoring at plasma membrane (GO:0007016)2.35346693
135regulation of hippo signaling (GO:0035330)2.33969383
136regulation of DNA damage checkpoint (GO:2000001)2.33602415
137peptidyl-lysine trimethylation (GO:0018023)2.33527839
138epithelial cell-cell adhesion (GO:0090136)2.33151034
139positive thymic T cell selection (GO:0045059)2.33038446
140establishment of mitochondrion localization (GO:0051654)2.32900697
141mesenchyme morphogenesis (GO:0072132)2.32487306
142trophoblast giant cell differentiation (GO:0060707)2.31924994
143generation of neurons (GO:0048699)2.31837225
144regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.31556859
145negative chemotaxis (GO:0050919)2.31421518
146regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.30924246
147snRNA metabolic process (GO:0016073)2.30895131
148neuron projection extension involved in neuron projection guidance (GO:1902284)2.29831321
149embryonic skeletal joint morphogenesis (GO:0060272)2.27853845
150positive regulation of DNA-dependent DNA replication (GO:2000105)2.27785936
151maternal placenta development (GO:0001893)2.27264272
152ganglion development (GO:0061548)2.26868987
153positive regulation of blood vessel endothelial cell migration (GO:0043536)2.26629375
154positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.25468086
155DNA damage induced protein phosphorylation (GO:0006975)2.25193998
156embryonic camera-type eye morphogenesis (GO:0048596)2.25084580
157basement membrane organization (GO:0071711)2.23285928
158cellular response to epidermal growth factor stimulus (GO:0071364)2.23276941
159DNA duplex unwinding (GO:0032508)2.22434201
160regulation of axon guidance (GO:1902667)2.22432457
161axon extension (GO:0048675)2.22171483
162insulin-like growth factor receptor signaling pathway (GO:0048009)2.21568712
163retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.20964549
164mesoderm formation (GO:0001707)2.20445689
165negative regulation of axon extension involved in axon guidance (GO:0048843)2.19876229
166positive regulation of synapse maturation (GO:0090129)2.18783549

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.43686595
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.49708187
3MYC_22102868_ChIP-Seq_BL_Human3.88170481
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.30733203
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.29250861
6TP63_17297297_ChIP-ChIP_HaCaT_Human3.18544467
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.11832499
8EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.04992408
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.83846935
10KDM2B_26808549_Chip-Seq_DND41_Human2.81839424
11ZFP281_18757296_ChIP-ChIP_E14_Mouse2.77478418
12ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.69750821
13* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.63066787
14* ZFP281_27345836_Chip-Seq_ESCs_Mouse2.60074804
15KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.55930149
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.51943330
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.50921538
18TCF7_22412390_ChIP-Seq_EML_Mouse2.45316002
19KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.38520169
20RARG_19884340_ChIP-ChIP_MEFs_Mouse2.38072382
21* ERG_21242973_ChIP-ChIP_JURKAT_Human2.29018162
22THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.26734419
23KDM2B_26808549_Chip-Seq_JURKAT_Human2.22156586
24* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.21377506
25VDR_21846776_ChIP-Seq_THP-1_Human2.20312376
26DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.11172547
27PKCTHETA_26484144_Chip-Seq_BREAST_Human2.10512435
28KDM2B_26808549_Chip-Seq_K562_Human2.05916256
29EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.02444210
30TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.91885249
31ESR1_15608294_ChIP-ChIP_MCF-7_Human1.90956488
32ZNF263_19887448_ChIP-Seq_K562_Human1.84959337
33ELK3_25401928_ChIP-Seq_HUVEC_Human1.83979554
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.81201461
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80422126
36SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.77043951
37CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.75636173
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.68942468
39* UTX_26944678_Chip-Seq_JUKART_Human1.66474018
40KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.62077053
41SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.61573979
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.59139957
43P300_27058665_Chip-Seq_ZR-75-30cells_Human1.58536002
44CIITA_25753668_ChIP-Seq_RAJI_Human1.58024745
45TET1_21451524_ChIP-Seq_MESCs_Mouse1.53363349
46TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48465621
47FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.47546043
48* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.46695540
49LXR_22292898_ChIP-Seq_THP-1_Human1.43811091
50MYC_18555785_ChIP-Seq_MESCs_Mouse1.43535779
51EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.43428693
52ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.42464997
53FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.41735897
54ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.41030399
55CREB1_26743006_Chip-Seq_LNCaP_Human1.39973947
56SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.39723864
57NANOG_21062744_ChIP-ChIP_HESCs_Human1.37749168
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36683967
59* MAF_26560356_Chip-Seq_TH1_Human1.36272573
60SMC4_20622854_ChIP-Seq_HELA_Human1.33097907
61ISL1_27105846_Chip-Seq_CPCs_Mouse1.32124358
62CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.31642181
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.31010566
64EZH2_22144423_ChIP-Seq_EOC_Human1.29704474
65TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29210375
66CLOCK_20551151_ChIP-Seq_293T_Human1.28268593
67HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.25530075
68UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.24395462
69* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.24129091
70* CTCF_27219007_Chip-Seq_Bcells_Human1.23548934
71* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22760737
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.21848316
73NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.21506951
74NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.20985790
75SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.20539417
76RING1B_27294783_Chip-Seq_NPCs_Mouse1.18148864
77CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.17509688
78* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.17175617
79* RACK7_27058665_Chip-Seq_MCF-7_Human1.16756099
80SRY_22984422_ChIP-ChIP_TESTIS_Rat1.15318667
81RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15213208
82ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15156559
83DNAJC2_21179169_ChIP-ChIP_NT2_Human1.14970512
84OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.14890452
85RARB_27405468_Chip-Seq_BRAIN_Mouse1.14510691
86MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.13770088
87CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.13048051
88* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.12980961
89RNF2_18974828_ChIP-Seq_MESCs_Mouse1.12909704
90EZH2_18974828_ChIP-Seq_MESCs_Mouse1.12909704
91SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.12462207
92NCOR1_26117541_ChIP-Seq_K562_Human1.11756073
93TET1_21490601_ChIP-Seq_MESCs_Mouse1.11657211
94DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.09420173
95E2F1_21310950_ChIP-Seq_MCF-7_Human1.09332001
96POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.09271138
97DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.08350775
98RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07771653
99CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.07615970
100PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05499192
101P68_20966046_ChIP-Seq_HELA_Human1.04909141
102NANOG_18555785_ChIP-Seq_MESCs_Mouse1.04907887
103BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.04811278
104TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.04568160
105EZH2_27304074_Chip-Seq_ESCs_Mouse1.04445523
106STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.04385639
107MYC_18358816_ChIP-ChIP_MESCs_Mouse1.04190202
108TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.03808812
109MAF_26560356_Chip-Seq_TH2_Human1.03144347
110PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.02288650
111SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.01188806
112EED_16625203_ChIP-ChIP_MESCs_Mouse1.00931937
113PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.99451963
114CHD1_26751641_Chip-Seq_LNCaP_Human0.99158601
115XRN2_22483619_ChIP-Seq_HELA_Human0.98602646
116* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.98296437
117RING1B_27294783_Chip-Seq_ESCs_Mouse0.98204890
118TRIM28_21343339_ChIP-Seq_HEK293_Human0.98078065
119ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97653814
120KLF4_18555785_ChIP-Seq_MESCs_Mouse0.97274142
121E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.95688913
122VDR_24763502_ChIP-Seq_THP-1_Human0.94690545
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94360451
124MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93583378
125POU5F1_16518401_ChIP-PET_MESCs_Mouse0.93234514
126TP53_22127205_ChIP-Seq_IMR90_Human0.91683231
127RUNX1_27514584_Chip-Seq_MCF-7_Human0.90301145
128ATF3_27146783_Chip-Seq_COLON_Human0.90269828
129FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.90037913
130TP53_20018659_ChIP-ChIP_R1E_Mouse0.89974250
131IKZF1_21737484_ChIP-ChIP_HCT116_Human0.89597091
132AR_21909140_ChIP-Seq_LNCAP_Human0.89258205
133POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.88815238
134SOX2_18555785_ChIP-Seq_MESCs_Mouse0.88184123
135* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86473493
136KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.85877762
137SA1_27219007_Chip-Seq_ERYTHROID_Human0.85546749
138FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.84766695
139RNF2_27304074_Chip-Seq_ESCs_Mouse0.84050467

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010030_abnormal_orbit_morphology3.39351324
2MP0002653_abnormal_ependyma_morphology3.05031188
3MP0005076_abnormal_cell_differentiation2.95566480
4MP0003122_maternal_imprinting2.75920132
5MP0000537_abnormal_urethra_morphology2.73571682
6MP0003121_genomic_imprinting2.43491158
7MP0000566_synostosis2.38227367
8MP0008438_abnormal_cutaneous_collagen2.28284310
9MP0000778_abnormal_nervous_system2.12063405
10MP0003123_paternal_imprinting2.08998251
11MP0001849_ear_inflammation2.08450271
12MP0003705_abnormal_hypodermis_morpholog2.05246404
13MP0004185_abnormal_adipocyte_glucose2.02927917
14MP0003115_abnormal_respiratory_system2.02306385
15MP0009053_abnormal_anal_canal2.02067513
16MP0004859_abnormal_synaptic_plasticity1.91206782
17MP0003111_abnormal_nucleus_morphology1.87807934
18MP0004272_abnormal_basement_membrane1.81327374
19MP0008789_abnormal_olfactory_epithelium1.79301466
20MP0002234_abnormal_pharynx_morphology1.78942852
21MP0003283_abnormal_digestive_organ1.75940826
22MP0003119_abnormal_digestive_system1.73710373
23MP0008961_abnormal_basal_metabolism1.73354782
24MP0005394_taste/olfaction_phenotype1.73149960
25MP0005499_abnormal_olfactory_system1.73149960
26MP0002084_abnormal_developmental_patter1.71957283
27MP0003566_abnormal_cell_adhesion1.70960851
28MP0000428_abnormal_craniofacial_morphol1.66974453
29MP0003890_abnormal_embryonic-extraembry1.66008382
30MP0004197_abnormal_fetal_growth/weight/1.65936657
31MP0003861_abnormal_nervous_system1.65356683
32MP0009278_abnormal_bone_marrow1.63806533
33MP0010352_gastrointestinal_tract_polyps1.61958589
34MP0005423_abnormal_somatic_nervous1.61361636
35MP0005187_abnormal_penis_morphology1.60261285
36MP0000049_abnormal_middle_ear1.59819169
37MP0001730_embryonic_growth_arrest1.58784145
38MP0002085_abnormal_embryonic_tissue1.58612030
39MP0005409_darkened_coat_color1.57749355
40MP0010094_abnormal_chromosome_stability1.57123136
41MP0000579_abnormal_nail_morphology1.54619154
42MP0002822_catalepsy1.53788642
43MP0003935_abnormal_craniofacial_develop1.53437233
44MP0000733_abnormal_muscle_development1.50301975
45MP0003077_abnormal_cell_cycle1.49554322
46MP0000350_abnormal_cell_proliferation1.48539292
47MP0005248_abnormal_Harderian_gland1.47707377
48MP0003385_abnormal_body_wall1.47623736
49MP0003787_abnormal_imprinting1.46305100
50MP0000762_abnormal_tongue_morphology1.45563576
51MP0000003_abnormal_adipose_tissue1.39349246
52MP0003937_abnormal_limbs/digits/tail_de1.36559116
53MP0002249_abnormal_larynx_morphology1.36518720
54MP0009384_cardiac_valve_regurgitation1.36312124
55MP0002092_abnormal_eye_morphology1.35820799
56MP0005380_embryogenesis_phenotype1.32114340
57MP0001672_abnormal_embryogenesis/_devel1.32114340
58MP0002116_abnormal_craniofacial_bone1.31482395
59MP0002877_abnormal_melanocyte_morpholog1.31107235
60MP0003755_abnormal_palate_morphology1.30909868
61MP0009250_abnormal_appendicular_skeleto1.29398532
62MP0002932_abnormal_joint_morphology1.28302750
63MP0001697_abnormal_embryo_size1.28164828
64MP0004957_abnormal_blastocyst_morpholog1.26443321
65MP0003693_abnormal_embryo_hatching1.24569708
66MP0003942_abnormal_urinary_system1.23949235
67MP0003984_embryonic_growth_retardation1.23202757
68MP0002088_abnormal_embryonic_growth/wei1.21868957
69MP0008932_abnormal_embryonic_tissue1.21268972
70MP0000955_abnormal_spinal_cord1.20884598
71MP0000751_myopathy1.20875407
72MP0000534_abnormal_ureter_morphology1.20585625
73MP0001293_anophthalmia1.18228055
74MP0010234_abnormal_vibrissa_follicle1.17421303
75MP0005503_abnormal_tendon_morphology1.16994766
76MP0000703_abnormal_thymus_morphology1.15030253
77MP0002086_abnormal_extraembryonic_tissu1.15007996
78MP0004811_abnormal_neuron_physiology1.14461867
79MP0001348_abnormal_lacrimal_gland1.12270009
80MP0005623_abnormal_meninges_morphology1.12104057
81MP0000432_abnormal_head_morphology1.12097557
82MP0005508_abnormal_skeleton_morphology1.11046726
83MP0005666_abnormal_adipose_tissue1.10758928
84MP0003938_abnormal_ear_development1.09888164
85MP0002081_perinatal_lethality1.08496187
86MP0003279_aneurysm1.08312056
87MP0000678_abnormal_parathyroid_gland1.07840750
88MP0009672_abnormal_birth_weight1.07422623
89MP0004808_abnormal_hematopoietic_stem1.05876240
90MP0000569_abnormal_digit_pigmentation1.05700621
91MP0004858_abnormal_nervous_system1.05099206
92MP0002080_prenatal_lethality1.04751872
93MP0002152_abnormal_brain_morphology1.04690529
94MP0008770_decreased_survivor_rate1.04312589
95MP0002282_abnormal_trachea_morphology1.03440257
96MP0000383_abnormal_hair_follicle1.03327059
97MP0001346_abnormal_lacrimal_gland1.02433793
98MP0010678_abnormal_skin_adnexa0.98709893
99MP0009703_decreased_birth_body0.98309807
100MP0002060_abnormal_skin_morphology0.96873081
101MP0002925_abnormal_cardiovascular_devel0.96684329
102MP0005501_abnormal_skin_physiology0.96469135
103MP0002697_abnormal_eye_size0.95934695
104MP0005375_adipose_tissue_phenotype0.95444277
105MP0002233_abnormal_nose_morphology0.94773894
106MP0003315_abnormal_perineum_morphology0.94169992
107MP0008057_abnormal_DNA_replication0.94081410
108MP0008007_abnormal_cellular_replicative0.93429729
109MP0003763_abnormal_thymus_physiology0.90424159
110MP0002114_abnormal_axial_skeleton0.87330928
111MP0006292_abnormal_olfactory_placode0.87161576
112MP0001340_abnormal_eyelid_morphology0.87095582
113MP0004233_abnormal_muscle_weight0.86929955
114MP0001958_emphysema0.84679405
115MP0002184_abnormal_innervation0.84370831
116MP0001270_distended_abdomen0.84134885
117MP0002111_abnormal_tail_morphology0.82607934
118MP0002751_abnormal_autonomic_nervous0.82140144
119MP0000467_abnormal_esophagus_morphology0.81711010
120MP0002089_abnormal_postnatal_growth/wei0.81472529
121MP0006138_congestive_heart_failure0.81127787
122MP0005257_abnormal_intraocular_pressure0.80547071
123MP0000759_abnormal_skeletal_muscle0.80119272
124MP0008877_abnormal_DNA_methylation0.79516341
125MP0001299_abnormal_eye_distance/0.78452907
126MP0001286_abnormal_eye_development0.76865758
127MP0010307_abnormal_tumor_latency0.76625396
128MP0000462_abnormal_digestive_system0.76618839
129MP0010368_abnormal_lymphatic_system0.76525649
130MP0005197_abnormal_uvea_morphology0.76449695
131MP0003091_abnormal_cell_migration0.74245333

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)4.27195024
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.27195024
3Hyperacusis (HP:0010780)4.02118246
4Premature rupture of membranes (HP:0001788)3.75275595
5Renal duplication (HP:0000075)3.52132722
6Broad face (HP:0000283)3.35379997
7Abnormality of the 4th metacarpal (HP:0010012)3.29650157
8Trigonocephaly (HP:0000243)3.28354555
9Elfin facies (HP:0004428)3.13025146
10Overriding aorta (HP:0002623)2.99930165
11Renovascular hypertension (HP:0100817)2.99929573
12Shallow orbits (HP:0000586)2.99212968
13Insomnia (HP:0100785)2.89137540
14Increased nuchal translucency (HP:0010880)2.85609000
15Cervical subluxation (HP:0003308)2.83593701
16Flat cornea (HP:0007720)2.62392383
17Obstructive sleep apnea (HP:0002870)2.58277512
18Pointed chin (HP:0000307)2.55660916
19Disproportionate tall stature (HP:0001519)2.50718678
20Biconcave vertebral bodies (HP:0004586)2.41356450
21Broad metatarsal (HP:0001783)2.38950879
22Broad distal phalanx of finger (HP:0009836)2.33841801
23Bowel diverticulosis (HP:0005222)2.33574579
24Heterotopia (HP:0002282)2.32248906
25Ependymoma (HP:0002888)2.30947882
26Abnormality of the diencephalon (HP:0010662)2.29612747
27Astrocytoma (HP:0009592)2.28311965
28Abnormality of the astrocytes (HP:0100707)2.28311965
29Abnormality of the fingertips (HP:0001211)2.25715911
30Upper limb amyotrophy (HP:0009129)2.25151361
31Distal upper limb amyotrophy (HP:0007149)2.25151361
32Long eyelashes (HP:0000527)2.24094705
33Short nail (HP:0001799)2.23302023
34Sacral dimple (HP:0000960)2.22521280
35Neoplasm of the heart (HP:0100544)2.20441863
36Spinal rigidity (HP:0003306)2.14787813
37Bladder diverticulum (HP:0000015)2.14733476
38Macroorchidism (HP:0000053)2.14721201
39Deviation of the hallux (HP:0010051)2.13503919
40Fragile skin (HP:0001030)2.13087193
41Hallux valgus (HP:0001822)2.12856671
42Aplasia involving bones of the upper limbs (HP:0009823)2.11610493
43Aplasia of the phalanges of the hand (HP:0009802)2.11610493
44Aplasia involving bones of the extremities (HP:0009825)2.11610493
45Broad thumb (HP:0011304)2.10460125
46Thin ribs (HP:0000883)2.10430563
47Coronal craniosynostosis (HP:0004440)2.08191908
48Abnormality of dentin (HP:0010299)2.07064116
49Bronchomalacia (HP:0002780)2.06803229
50Megalocornea (HP:0000485)2.06577158
51Distal lower limb amyotrophy (HP:0008944)2.06285270
52Abnormality of oral frenula (HP:0000190)2.02500083
53Mitral regurgitation (HP:0001653)2.02305038
54Abnormal number of incisors (HP:0011064)2.01506813
55Abnormality of the phalanges of the hallux (HP:0010057)2.01080259
56Ankyloglossia (HP:0010296)2.00282777
57Flat acetabular roof (HP:0003180)1.99423128
58Atrophic scars (HP:0001075)1.99307214
59Abnormality of the lower motor neuron (HP:0002366)1.99234130
60Cerebral aneurysm (HP:0004944)1.98368374
61Obsessive-compulsive behavior (HP:0000722)1.97892295
62Spina bifida occulta (HP:0003298)1.97856122
63Volvulus (HP:0002580)1.97122076
64Bowing of the arm (HP:0006488)1.96362558
65Bowed forearm bones (HP:0003956)1.96362558
66Thin bony cortex (HP:0002753)1.96125266
67Increased density of long bones (HP:0006392)1.96106768
68Stridor (HP:0010307)1.94118488
69Amyotrophic lateral sclerosis (HP:0007354)1.93502461
70Abnormality of the calcaneus (HP:0008364)1.92413579
71Genu recurvatum (HP:0002816)1.91494823
72Patellar dislocation (HP:0002999)1.90197254
73Deviation of the thumb (HP:0009603)1.89975007
74Proximal placement of thumb (HP:0009623)1.88592302
75Medulloblastoma (HP:0002885)1.88538569
76Abnormality of the labia minora (HP:0012880)1.86893423
77Ulnar bowing (HP:0003031)1.86553811
78Asymmetry of the thorax (HP:0001555)1.84809505
79Selective tooth agenesis (HP:0001592)1.84206141
80Difficulty climbing stairs (HP:0003551)1.83905211
81Dislocated radial head (HP:0003083)1.83176966
82Skin tags (HP:0010609)1.81165848
83Supernumerary ribs (HP:0005815)1.80044720
84Narrow palate (HP:0000189)1.80005674
85Short 5th finger (HP:0009237)1.78979873
86Broad palm (HP:0001169)1.78978087
87Abnormality of the intervertebral disk (HP:0005108)1.78944810
88Short phalanx of the thumb (HP:0009660)1.77480510
89Abnormality of the radial head (HP:0003995)1.77431880
90Arnold-Chiari malformation (HP:0002308)1.77310112
91Pseudobulbar signs (HP:0002200)1.77154303
92Abnormality of the distal phalanx of the thumb (HP:0009617)1.76317521
93Bell-shaped thorax (HP:0001591)1.76273558
94Duplication of thumb phalanx (HP:0009942)1.76120134
95Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.75116803
96Mitral valve prolapse (HP:0001634)1.74945263
97Lower limb amyotrophy (HP:0007210)1.74649650
98Achilles tendon contracture (HP:0001771)1.74624973
99Long toe (HP:0010511)1.74465717
100Neoplasm of the oral cavity (HP:0100649)1.74336528
101Broad phalanges of the hand (HP:0009768)1.74048528
102Wrist flexion contracture (HP:0001239)1.73597359
103Wormian bones (HP:0002645)1.73113779
104Buphthalmos (HP:0000557)1.72976595
105Short clavicles (HP:0000894)1.70710377
106Facial hemangioma (HP:0000329)1.70366636
107Long palpebral fissure (HP:0000637)1.70181265
108Blue sclerae (HP:0000592)1.69239202
109High anterior hairline (HP:0009890)1.69196371
110Mildly elevated creatine phosphokinase (HP:0008180)1.69128232
111Congenital glaucoma (HP:0001087)1.68434817
112Glioma (HP:0009733)1.67918959
113Metaphyseal cupping (HP:0003021)1.67301833
114Hypoventilation (HP:0002791)1.67242604
115Hand muscle atrophy (HP:0009130)1.66155953
116Pelvic girdle muscle weakness (HP:0003749)1.65938301
117Midface retrusion (HP:0011800)1.65714898
118Neonatal short-limb short stature (HP:0008921)1.65694777
119Natal tooth (HP:0000695)1.65542755
120J-shaped sella turcica (HP:0002680)1.65128969
121Rib fusion (HP:0000902)1.64995113
122Turricephaly (HP:0000262)1.64956191
123Leiomyosarcoma (HP:0100243)1.64570819
124Uterine leiomyosarcoma (HP:0002891)1.64570819
125Precocious puberty (HP:0000826)1.63921760
126Subacute progressive viral hepatitis (HP:0006572)1.63145448
127T lymphocytopenia (HP:0005403)1.62912230
128Oligodactyly (HP:0012165)1.61437174
129Aplasia/Hypoplasia of the clavicles (HP:0006710)1.61260361
130Broad finger (HP:0001500)1.61158625
131Ankle contracture (HP:0006466)1.60812936
132Abnormal vertebral ossification (HP:0100569)1.60600243
133Abnormality of the aortic arch (HP:0012303)1.60184936
134Wide anterior fontanel (HP:0000260)1.60165630
135Deep philtrum (HP:0002002)1.59796697
136Tracheal stenosis (HP:0002777)1.59699085
137Attention deficit hyperactivity disorder (HP:0007018)1.59273744
138Partial duplication of the phalanx of hand (HP:0009999)1.58014383
139Abnormality of chromosome segregation (HP:0002916)1.57898107
140Entropion (HP:0000621)1.57568587
141Gastrointestinal carcinoma (HP:0002672)1.56566456
142Malignant gastrointestinal tract tumors (HP:0006749)1.56566456
143Overlapping toe (HP:0001845)1.55751090
144Annular pancreas (HP:0001734)1.55263852
145Basal cell carcinoma (HP:0002671)1.54286656
146Neoplasm of striated muscle (HP:0009728)1.54149412
147Vertebral arch anomaly (HP:0008438)1.52753598
148Protrusio acetabuli (HP:0003179)1.51793260
149Preauricular skin tag (HP:0000384)1.51677383
150Termporal pattern (HP:0011008)1.51462933
151Insidious onset (HP:0003587)1.51462933
152Spinal cord lesions (HP:0100561)1.50936196
153Syringomyelia (HP:0003396)1.50936196
154Patellar aplasia (HP:0006443)1.50678445
155Short 1st metacarpal (HP:0010034)1.50414823
156Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.50414823
157Broad phalanx (HP:0006009)1.50258818
158Transitional cell carcinoma of the bladder (HP:0006740)1.49764558
159Midline defect of the nose (HP:0004122)1.49528271
160Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.49100481
161Aqueductal stenosis (HP:0002410)1.48860124

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K104.02564827
2CDK123.52676735
3EEF2K3.24764931
4SMG13.12763817
5ICK2.96600099
6NTRK12.87036468
7TRIB32.68874803
8CDC72.54844341
9EPHA22.49715263
10BRD42.40816007
11LATS22.16717873
12PKN22.02411550
13LATS11.97750604
14TYRO31.96350628
15SIK21.95629547
16MAP3K91.88481646
17MET1.85727122
18NEK21.82382561
19KSR11.71243970
20ALK1.67241284
21MST1R1.65747768
22PDGFRA1.64734249
23IRAK31.42705039
24MTOR1.41913508
25PAK61.39757439
26RIPK11.39430091
27TAOK11.38462586
28EPHB21.32858832
29MARK11.24931150
30MAP2K31.23714253
31TESK21.19148749
32PTK61.18946808
33FGFR41.17514323
34KSR21.15637540
35NTRK21.12964767
36PRPF4B1.11888085
37FGFR21.10253355
38PDGFRB1.06730256
39TTN1.06406727
40DDR21.05686393
41ACVR1B1.02944383
42FGFR11.02753040
43ERBB21.00135742
44MAP3K60.98954972
45CDK80.98885021
46MAP3K40.98316783
47UHMK10.98100247
48NME20.97737779
49CAMK1G0.97406155
50CDK40.96203349
51BMX0.94118019
52RPS6KB20.94019256
53CHEK10.93615896
54EPHA30.92405070
55ERN10.91583027
56PRKD30.90820862
57STK100.90171420
58PAK40.90097589
59MARK20.88697333
60CDK60.87048152
61ATR0.86548645
62TGFBR10.83723028
63CHEK20.83272624
64SIK10.82448533
65FLT30.81680049
66GRK60.81543971
67MAP3K70.81196490
68PRKD20.81087610
69BRSK10.80272926
70MAP4K10.79785991
71PTK20.78957423
72CSNK1A1L0.77467076
73MELK0.76686958
74CDK20.76677219
75TTK0.75726958
76MINK10.74417560
77DMPK0.73613811
78ILK0.72647736
79PAK20.72257286
80CDK70.70326332
81CAMKK10.70284279
82PASK0.70212939
83TESK10.67973553
84ERBB40.67700746
85STK30.67581128
86MAP3K130.64217369
87MKNK10.64027804
88TSSK60.63333945
89RPS6KC10.62933125
90RPS6KL10.62933125
91RPS6KA10.61960111
92DYRK1A0.61689846
93PRKCH0.61615890
94SRPK10.60596841
95RET0.60378270
96ROCK20.59334661
97MAP2K40.59181344
98CDK10.58453541
99MAP2K20.58189791
100MAP3K80.57604609
101CDK90.56210832
102CDC42BPA0.55475368
103PNCK0.54709429
104RPS6KA20.54550950
105CAMK1D0.54300766
106MAPK100.53994401
107MAPK90.53260262
108CSNK1E0.52151290
109CSNK1G20.51894404
110PAK30.51783824
111MAPK140.50479832
112TAF10.50455970
113ATM0.50213611
114GSK3B0.49867770
115ITK0.49128909
116AURKA0.49041776
117IRAK20.48816228
118BUB10.48809505
119CSNK1D0.48339434
120STK380.47957921
121SCYL20.47106104
122CSNK1G30.46693766
123HIPK20.46475766
124AKT20.46419584
125LMTK20.45636028
126MAPK80.45259479
127CDK150.44452722
128CDK180.43522951
129BRAF0.42914216
130RPS6KA60.42699551
131VRK20.42336534
132MAP2K60.42321680
133CDK11A0.42069881
134LRRK20.41845590
135NME10.41525664
136CDK140.41378652
137RAF10.41098792
138EPHB10.39830384
139PRKCI0.36194247
140WNK10.35094227
141CLK10.31956709
142AURKB0.31252971

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052172.26557105
2mRNA surveillance pathway_Homo sapiens_hsa030151.90406668
3ECM-receptor interaction_Homo sapiens_hsa045121.88595405
4Colorectal cancer_Homo sapiens_hsa052101.84475068
5Chronic myeloid leukemia_Homo sapiens_hsa052201.76573060
6Hippo signaling pathway_Homo sapiens_hsa043901.75353307
7Axon guidance_Homo sapiens_hsa043601.73717256
8Notch signaling pathway_Homo sapiens_hsa043301.69933028
9Endometrial cancer_Homo sapiens_hsa052131.69113090
10MicroRNAs in cancer_Homo sapiens_hsa052061.64456913
11Hedgehog signaling pathway_Homo sapiens_hsa043401.61472743
12mTOR signaling pathway_Homo sapiens_hsa041501.56750080
13Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.54365799
14Spliceosome_Homo sapiens_hsa030401.53306250
15Cell cycle_Homo sapiens_hsa041101.51190561
16Other glycan degradation_Homo sapiens_hsa005111.40915370
17Non-small cell lung cancer_Homo sapiens_hsa052231.40683062
18T cell receptor signaling pathway_Homo sapiens_hsa046601.38626521
19Wnt signaling pathway_Homo sapiens_hsa043101.37099827
20Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.35540754
21Thyroid hormone signaling pathway_Homo sapiens_hsa049191.33763028
22Glioma_Homo sapiens_hsa052141.33463557
23Dorso-ventral axis formation_Homo sapiens_hsa043201.32866192
24Adherens junction_Homo sapiens_hsa045201.31490847
25HTLV-I infection_Homo sapiens_hsa051661.31285580
26Lysine degradation_Homo sapiens_hsa003101.30380929
27Proteoglycans in cancer_Homo sapiens_hsa052051.29091002
28Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.27032904
29Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.26704070
30Oocyte meiosis_Homo sapiens_hsa041141.24409679
31Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.23971140
32Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21583327
33Pancreatic cancer_Homo sapiens_hsa052121.21524374
34RNA transport_Homo sapiens_hsa030131.20689721
35Neurotrophin signaling pathway_Homo sapiens_hsa047221.19270143
36VEGF signaling pathway_Homo sapiens_hsa043701.19061866
37Cyanoamino acid metabolism_Homo sapiens_hsa004601.17075997
38Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.14227266
39Primary immunodeficiency_Homo sapiens_hsa053401.12358509
40Melanogenesis_Homo sapiens_hsa049161.11747991
41Renal cell carcinoma_Homo sapiens_hsa052111.11263742
42Estrogen signaling pathway_Homo sapiens_hsa049151.09324693
43ErbB signaling pathway_Homo sapiens_hsa040121.05731858
44Glycosaminoglycan degradation_Homo sapiens_hsa005311.05489268
45Biosynthesis of amino acids_Homo sapiens_hsa012301.03471455
46Dilated cardiomyopathy_Homo sapiens_hsa054141.02977196
47Small cell lung cancer_Homo sapiens_hsa052221.01753235
48Viral myocarditis_Homo sapiens_hsa054160.96642198
49Acute myeloid leukemia_Homo sapiens_hsa052210.95492892
50Bladder cancer_Homo sapiens_hsa052190.94867920
51Prostate cancer_Homo sapiens_hsa052150.94774035
52Type II diabetes mellitus_Homo sapiens_hsa049300.94005806
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.93717517
54Gap junction_Homo sapiens_hsa045400.93583067
55Long-term potentiation_Homo sapiens_hsa047200.92771208
56Viral carcinogenesis_Homo sapiens_hsa052030.92363120
57Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89842979
58Choline metabolism in cancer_Homo sapiens_hsa052310.89366095
59Pathways in cancer_Homo sapiens_hsa052000.88806636
60Prion diseases_Homo sapiens_hsa050200.88699045
61Central carbon metabolism in cancer_Homo sapiens_hsa052300.88033821
62GnRH signaling pathway_Homo sapiens_hsa049120.87556079
63Longevity regulating pathway - mammal_Homo sapiens_hsa042110.87414573
64Hepatitis B_Homo sapiens_hsa051610.87197745
65B cell receptor signaling pathway_Homo sapiens_hsa046620.87097435
66Thyroid cancer_Homo sapiens_hsa052160.86153760
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.86080853
68Sulfur relay system_Homo sapiens_hsa041220.85885167
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.83754944
70Focal adhesion_Homo sapiens_hsa045100.83589758
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83396991
72MAPK signaling pathway_Homo sapiens_hsa040100.83390484
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.82863862
74FoxO signaling pathway_Homo sapiens_hsa040680.82780133
75TGF-beta signaling pathway_Homo sapiens_hsa043500.82608019
76Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.82167168
77Inositol phosphate metabolism_Homo sapiens_hsa005620.81075234
78N-Glycan biosynthesis_Homo sapiens_hsa005100.81048040
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.80827032
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.80144083
81p53 signaling pathway_Homo sapiens_hsa041150.80022174
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79392084
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78750844
84Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.78199847
85Prolactin signaling pathway_Homo sapiens_hsa049170.78030410
862-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.76582876
87Rap1 signaling pathway_Homo sapiens_hsa040150.76164913
88Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75509868
89Tight junction_Homo sapiens_hsa045300.75303148
90Transcriptional misregulation in cancer_Homo sapiens_hsa052020.73951598
91DNA replication_Homo sapiens_hsa030300.72030345
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70675168
93Oxytocin signaling pathway_Homo sapiens_hsa049210.70437783
94Leukocyte transendothelial migration_Homo sapiens_hsa046700.70157847
95Insulin signaling pathway_Homo sapiens_hsa049100.68114414
96Pentose phosphate pathway_Homo sapiens_hsa000300.67920713
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.67873821
98Dopaminergic synapse_Homo sapiens_hsa047280.67651252
99Aldosterone synthesis and secretion_Homo sapiens_hsa049250.67565686
100Amoebiasis_Homo sapiens_hsa051460.66943605
101PI3K-Akt signaling pathway_Homo sapiens_hsa041510.66788980
102Base excision repair_Homo sapiens_hsa034100.66728651
103Endocytosis_Homo sapiens_hsa041440.66534527
104Gastric acid secretion_Homo sapiens_hsa049710.65621025
105Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.65284062
106Cocaine addiction_Homo sapiens_hsa050300.63942231
107AMPK signaling pathway_Homo sapiens_hsa041520.61859501
108Nucleotide excision repair_Homo sapiens_hsa034200.60944047
109Shigellosis_Homo sapiens_hsa051310.60480879
110Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59893967
111Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59058091
112Platelet activation_Homo sapiens_hsa046110.58155013
113Alcoholism_Homo sapiens_hsa050340.57284647
114Vibrio cholerae infection_Homo sapiens_hsa051100.57193058
115Cholinergic synapse_Homo sapiens_hsa047250.57140097
116Melanoma_Homo sapiens_hsa052180.56629947
117Glutamatergic synapse_Homo sapiens_hsa047240.55990016
118Vitamin B6 metabolism_Homo sapiens_hsa007500.55544018
119Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55496700
120Epstein-Barr virus infection_Homo sapiens_hsa051690.55173385
121Chemokine signaling pathway_Homo sapiens_hsa040620.54246183
122Apoptosis_Homo sapiens_hsa042100.53912498
123cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53668018
124Herpes simplex infection_Homo sapiens_hsa051680.52807534
125Protein digestion and absorption_Homo sapiens_hsa049740.49748394

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